Papers that used NIH HPC Systems resources

Papers that used Biowulf or Helix resources

If you have published research that has made significant use of these systems, please let us know by sending email to staff@hpc.nih.gov

2019 to date (106 papers)

Subtle predictive movements reveal actions regardless of social context McMahon, EG; Zheng, CY; Pereira, F; Gonzalez, R; Ungerleider, LG; Vaziri-Pashkam, M; J Vis, DOI://10.1167/19.7.16 (2019)
Evidence for the Interaction of A3 Adenosine Receptor Agonists at the Drug-Binding Site(s) of Human P-glycoprotein (ABCB1) Abel, B; Tosh, DK; Durell, SR et al. Mol. Pharmacol., DOI://10.1124/mol.118.115295 (2019)
Eye in a Disk: eyeIntegration Human Pan-Eye and Body Transcriptome Database Version 1.0 Swamy, V; McGaughey, D; Invest. Ophthalmol. Vis. Sci., DOI://10.1167/iovs.19-27106 (2019)

Meta-analysis of GWA studies provides new insights on the genetic architecture of skin pigmentation in recently admixed populations Lona-Durazo, F; Hernandez-Pacheco, N; Fan, S et al. BMC Genet., DOI://10.1186/s12863-019-0765-5 (2019)
Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis Deniset, JF; Belke, D; Lee, WY et al. Immunity, DOI://10.1016/j.immuni.2019.06.010 (2019)
Amino-acid inserts of HIV-1 capsid (CA) induce CA degradation and abrogate viral infectivity: Insights for the dynamics and mechanisms of HIV-1 CA decomposition Amano, M; Bulut, H; Tamiya, S; Nakamura, T; Koh, Y; Mitsuya, H; Sci Rep, DOI://10.1038/s41598-019-46082-2 (2019)
Novel Heterozygous Variants in KMT2D Associated with Holoprosencephaly Tekendo-Ngongang, C; Kruszka, P; Martinez, AF; Muenke, M; Clin. Genet., DOI://10.1111/cge.13598 (2019)
A critical review of five machine learning-based algorithms for predicting protein stability changes upon mutation Fang, J Brief. Bioinformatics, DOI://10.1093/bib/bbz071 (2019)
CPF Recruitment to Non-canonical Transcription Termination Sites Triggers Heterochromatin Assembly and Gene Silencing Vo, TV; Dhakshnamoorthy, J; Larkin, M et al. Cell Rep, DOI://10.1016/j.celrep.2019.05.107 (2019)

The structure-activity profile of mercaptobenzamides' anti-HIV activity suggests that thermodynamics of metabolism is more important than binding affinity to the target Nikolayevskiy, H; Robello, M; Scerba, MT et al. Eur J Med Chem, DOI://10.1016/j.ejmech.2019.06.020 (2019)
Author Correction: Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis Vogt, EJ; Tokuhiro, K; Guo, M et al. Nat Commun, DOI://10.1038/s41467-019-10935-1 (2019)
Maternal BMI-Increasing Genetic Risk Score and Fetal Weights among Diverse US Ethnic Groups Shrestha, D; Rahman, ML; Hinkle, SN; Workalemahu, T; Tekola-Ayele, F; Obesity (Silver Spring), DOI://10.1002/oby.22499 (2019)
RASA2 and NF1; two-negative regulators of Ras with complementary functions in melanoma Arafeh, R; Di Pizio, A; Elkahloun, AG; Dym, O; Niv, MY; Samuels, Y; Oncogene, DOI://10.1038/s41388-018-0578-4 (2019)
Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP Li, M; Wang, Y; Banerjee, R et al. Elife, DOI://10.7554/eLife.47060 (2019)
Deep learning-based muscle segmentation and quantification at abdominal CT: application to a longitudinal adult screening cohort for sarcopenia assessment Graffy, PM; Liu, J; Pickhardt, PJ; Burns, JE; Yao, J; Summers, RM; Br J Radiol, DOI://10.1259/bjr.20190327 (2019)

A parameterized digital 3D model of the Rhesus macaque face for investigating the visual processing of social cues Murphy, AP; Leopold, DA; J. Neurosci. Methods, DOI://10.1016/j.jneumeth.2019.06.001 (2019)
Small posterior fossa in Chiari I malformation affected families is significantly linked to 1q43-44 and 12q23-24.11 using whole exome sequencing Musolf, AM; Ho, WSC; Long, KA et al. Eur. J. Hum. Genet., DOI://10.1038/s41431-019-0457-7 (2019)
Association of Step Volume and Intensity With All-Cause Mortality in Older Women Lee, IM; Shiroma, EJ; Kamada, M; Bassett, DR; Matthews, CE; Buring, JE; JAMA Intern Med, DOI://10.1001/jamainternmed.2019.0899 (2019)
Novel Inter-omic Analysis Reveals Relationships Between Diverse Gut Microbiota and Host Immune Dysregulation in HLA-B27-Induced Experimental Spondyloarthritis Gill, T; Brooks, SR; Rosenbaum, JT; Asquith, M; Colbert, RA; , DOI://10.1002/art.41018 (2019)
Disordered RNA chaperones can enhance nucleic acid folding via local charge screening Holmstrom, ED; Liu, Z; Nettels, D; Best, RB; Schuler, B; Nat Commun, DOI://10.1038/s41467-019-10356-0 (2019)
Aicardi-Goutières syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast cancer Deasy, SK; Uehara, R; Vodnala, SK et al. PLoS Genet., DOI://10.1371/journal.pgen.1008020 (2019)

Fully automated prostate whole gland and central gland segmentation on MRI using holistically nested networks with short connections Cheng, R; Lay, N; Roth, HR et al. J Med Imaging (Bellingham), DOI://10.1117/1.JMI.6.2.024007 (2019)
Correlation between Disease Severity and the Intestinal Microbiome in Mycobacterium tuberculosis-Infected Rhesus Macaques Namasivayam, S; Kauffman, KD; McCulloch, JA et al. MBio, DOI://10.1128/mBio.01018-19 (2019)
Smartphone Level Test Measures Disability in Several Neurological Domains for Patients With Multiple Sclerosis Boukhvalova, AK; Fan, O; Weideman, AM et al. Front Neurol, DOI://10.3389/fneur.2019.00358 (2019)
A chromosome-scale assembly of the major African malaria vector Anopheles funestus Ghurye, J; Koren, S; Small, ST et al. Gigascience, DOI://10.1093/gigascience/giz063 (2019)
An integrative Bayesian approach to matrix-based analysis in neuroimaging Chen, G; Bürkner, PC; Taylor, PA et al. Hum Brain Mapp, DOI://10.1002/hbm.24686 (2019)
REC114 Partner ANKRD31 Controls Number, Timing, and Location of Meiotic DNA Breaks Boekhout, M; Karasu, ME; Wang, J et al. Mol. Cell, DOI://10.1016/j.molcel.2019.03.023 (2019)

The Crystal Structure of Bacterial Cytochrome bc1 in Complex with Azoxystrobin Reveals a Conformation Switch of the Rieske Iron-Sulfur Protein Subunit Esser, L; Zhou, F; Yu, CA; Xia, D; J. Biol. Chem., DOI://10.1074/jbc.RA119.008381 (2019)
Atomic resolution cryo-EM structure of a native-like CENP-A nucleosome aided by an antibody fragment Zhou, BR; Yadav, KNS; Borgnia, M et al. Nat Commun, DOI://10.1038/s41467-019-10247-4 (2019)
XL-DNase-seq: improved footprinting of dynamic transcription factors Oh, KS; Ha, J; Baek, S; Sung, MH; Epigenetics Chromatin, DOI://10.1186/s13072-019-0277-6 (2019)
Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium Kobayashi, T; Voisin, B; Kim, DY et al. Cell, DOI://10.1016/j.cell.2018.12.031 (2019)
The skin transcriptome in hidradenitis suppurativa uncovers an antimicrobial and sweat gland gene signature which has distinct overlap with wounded skin Coates, M; Mariottoni, P; Corcoran, DL et al. PLoS ONE, DOI://10.1371/journal.pone.0216249 (2019)
The Transcriptome of the Salivary Glands of Amblyomma aureolatum Reveals the Antimicrobial Peptide Microplusin as an Important Factor for the Tick Protection Against Rickettsia rickettsii Infection Martins, LA; Malossi, CD; Galletti, MFBM et al. Front Physiol, DOI://10.3389/fphys.2019.00529 (2019)
Whole-Genome Sequences of Salmonella enterica Serovar I 4,[5],12:i:- Isolates from Swine Gonzalez, S; Harvey, RB; Scott, HM et al. Microbiol Resour Announc, DOI://10.1128/MRA.00223-19 (2019)
TFE3 Xp11.2 Translocation Renal Cell Carcinoma Mouse Model Reveals Novel Therapeutic Targets and Identifies GPNMB as a Diagnostic Marker for Human Disease Baba, M; Furuya, M; Motoshima, T et al. Mol. Cancer Res., DOI://10.1158/1541-7786.MCR-18-1235 (2019)
Banana (Musa acuminata) transcriptome profiling in response to rhizobacteria: Bacillus amyloliquefaciens Bs006 and Pseudomonas fluorescens Ps006 Gamez, RM; Rodríguez, F; Vidal, NM et al. BMC Genomics, DOI://10.1186/s12864-019-5763-5 (2019)
Early-childhood social reticence predicts SCR-BOLD coupling during fear extinction recall in preadolescent youth Michalska, KJ; Feldman, JS; Ivie, EJ et al. Dev Cogn Neurosci, DOI://10.1016/j.dcn.2018.12.003 (2019)
miR-155 harnesses Phf19 to potentiate cancer immunotherapy through epigenetic reprogramming of CD8+ T cell fate Ji, Y; Fioravanti, J; Zhu, W et al. Nat Commun, DOI://10.1038/s41467-019-09882-8 (2019)
Physical Activity Patterns and Mortality: The Weekend Warrior and Activity Bouts Shiroma, EJ; Lee, IM; Schepps, MA; Kamada, M; Harris, TB; Med Sci Sports Exerc, DOI://10.1249/MSS.0000000000001762 (2019)

Heritability and genetic variance of dementia with Lewy bodies Guerreiro, R; Escott-Price, V; Hernandez, DG et al. Neurobiol. Dis., DOI://10.1016/j.nbd.2019.04.004 (2019)
Differential Brain Mechanisms of Selection and Maintenance of Information during Working Memory Quentin, R; King, JR; Sallard, E et al. J. Neurosci., DOI://10.1523/JNEUROSCI.2764-18.2019 (2019)
High dimensional mediation analysis with latent variables Derkach, A; Pfeiffer, RM; Chen, TH; Sampson, JN; Biometrics, DOI://10.1111/biom.13053 (2019)
Characterization of the Phosphorylation Site of GRTH/DDX25 and Protein Kinase A Binding Interface Provides Structural Basis for the Design of a Non-Hormonal Male Contraceptive Raju, M; Hassan, SA; Kavarthapu, R; Anbazhagan, R; Dufau, ML; Sci Rep, DOI://10.1038/s41598-019-42857-9 (2019)
Frontal alpha asymmetry moderates the relations between behavioral inhibition and social-effect ERN Harrewijn, A; Buzzell, GA; Debnath, R; Leibenluft, E; Pine, DS; Fox, NA; Biol Psychol, DOI://10.1016/j.biopsycho.2018.12.014 (2019)
Identification of Neoantigen-Reactive Tumor-Infiltrating Lymphocytes in Primary Bladder Cancer Leko, V; McDuffie, LA; Zheng, Z et al. J. Immunol., DOI://10.4049/jimmunol.1801022 (2019)

Evolution of All-Atom Protein Force Fields to Improve Local and Global Properties Zerze, GH; Zheng, W; Best, RB; Mittal, J; J Phys Chem Lett, DOI://10.1021/acs.jpclett.9b00850 (2019)
The mechanism of PI3Kα activation at the atomic level Zhang, M; Jang, H; Nussinov, R; Chem Sci, DOI://10.1039/c8sc04498h (2019)
Association Between Childhood Anhedonia and Alterations in Large-Scale Resting-State Networks and Task-Evoked Activation Pornpattananangkul, N; Leibenluft, E; Pine, DS; Stringaris, A; JAMA Psychiatry, DOI://10.1001/jamapsychiatry.2019.0020 (2019)
SOX2 Epidermal Overexpression Promotes Cutaneous Wound Healing via Activation of EGFR/MEK/ERK Signaling Mediated by EGFR Ligands Uchiyama, A; Nayak, S; Graf, R et al. J. Invest. Dermatol., DOI://10.1016/j.jid.2019.02.004 (2019)
Automated segmentation and quantification of aortic calcification at abdominal CT: application of a deep learning-based algorithm to a longitudinal screening cohort Graffy, PM; Liu, J; O'Connor, S; Summers, RM; Pickhardt, PJ; Abdom Radiol (NY), DOI://10.1007/s00261-019-02014-2 (2019)
A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex Marabelli, C; Marrocco, B; Pilotto, S et al. Cell Rep, DOI://10.1016/j.celrep.2019.03.061 (2019)

Halogen bond interactions of novel HIV-1 protease inhibitors (PI)(GRL-001-15 and GRL-003-15) with the flap of protease are critical for their potent activity against wild-type and multi-PI-resistant HIV-1 variants Hattori, SI; Hayashi, H; Bulut, H et al. Antimicrob. Agents Chemother., DOI://10.1128/AAC.02635-18 (2019)
Parkinson's disease age at onset genome-wide association study: Defining heritability, genetic loci, and α-synuclein mechanisms Blauwendraat, C; Heilbron, K; Vallerga, CL et al. Mov. Disord., DOI://10.1002/mds.27659 (2019)
Absolute risks of cervical precancer among women who fulfill exiting guidelines based on HPV and cytology cotesting Landy, R; Schiffman, M; Sasieni, PD et al. Int. J. Cancer, DOI://10.1002/ijc.32268 (2019)
Inference for case-control studies with incident and prevalent cases Maziarz, M; Liu, Y; Qin, J; Pfeiffer, RM; Biometrics, DOI://10.1111/biom.13023 (2019)
Human Influenza A Virus Hemagglutinin Glycan Evolution Follows a Temporal Pattern to a Glycan Limit Altman, MO; Angel, M; Košík, I et al. MBio, DOI://10.1128/mBio.00204-19 (2019)
Shared genetic underpinnings of childhood obesity and adult cardiometabolic diseases Tekola-Ayele, F; Lee, A; Workalemahu, T; Sánchez-Pozos, K; Hum. Genomics, DOI://10.1186/s40246-019-0202-x (2019)

Human-Origin Influenza A (H3N2) Reassortant Viruses in Swine, Southeast Mexico Nelson, MI; Souza, CK; Trovão, NS et al. Emerging Infect. Dis., DOI://10.3201/eid2504.180779 (2019)
Posture-dependent dose coefficients of mesh-type ICRP reference computational phantoms for photon external exposures Yeom, YS; Han, H; Choi, C et al. Phys Med Biol, DOI://10.1088/1361-6560/ab0917 (2019)
Revisiting Volumes of Lipid Components in Bilayers Nagle, JF; Venable, RM; Maroclo-Kemmerling, E; Tristram-Nagle, S; Harper, PE; Pastor, RW; J Phys Chem B, DOI://10.1021/acs.jpcb.8b12010 (2019)
Single-cell chromatin immunocleavage sequencing (scChIC-seq) to profile histone modification Ku, WL; Nakamura, K; Gao, W et al. Nat. Methods, DOI://10.1038/s41592-019-0361-7 (2019)
Biophysical mechanisms in the mammalian respiratory oscillator re-examined with a new data-driven computational model Phillips, RS; John, TT; Koizumi, H; Molkov, YI; Smith, JC; Elife, DOI://10.7554/eLife.41555 (2019)
A Bayesian hierarchical logistic regression model of multiple informant family health histories Lin, J; Myers, MF; Koehly, LM; Marcum, CS; BMC Med Res Methodol, DOI://10.1186/s12874-019-0700-5 (2019)

Automated Computational Detection, Quantitation, and Mapping of Mitosis in Whole-Slide Images for Clinically Actionable Surgical Pathology Decision Support Puri, M; Hoover, SB; Hewitt, SM et al. J Pathol Inform, DOI://10.4103/jpi.jpi_59_18 (2019)
Contrasting roles of the RSC and ISW1/CHD1 chromatin remodelers in RNA polymerase II elongation and termination Ocampo, J; Chereji, RV; Eriksson, PR; Clark, DJ; Genome Res., DOI://10.1101/gr.242032.118 (2019)
Control and Regulation of Substrate Selection in Cytoplasmic and Mitochondrial Catabolic Networks. A Systems Biology Analysis Cortassa, S; Aon, MA; Sollott, SJ; Front Physiol, DOI://10.3389/fphys.2019.00201 (2019)
CMCdG, a Novel Nucleoside Analog with Favorable Safety Features, Exerts Potent Activity against Wild-Type and Entecavir-Resistant Hepatitis B Virus Higashi-Kuwata, N; Hayashi, S; Das, D et al. Antimicrob. Agents Chemother., DOI://10.1128/AAC.02143-18 (2019)
Subset testing and analysis of multiple phenotypes Derkach, A; Pfeiffer, RM; Genet. Epidemiol., DOI://10.1002/gepi.22199 (2019)
Semi-Automated 3D Segmentation of Human Skeletal Muscle Using Focused Ion Beam-Scanning Electron Microscopic Images Caffrey, B; Maltsev, AV; Gonzalez-Freire, M; Hartnell, LM; Ferrucci, L; Subramaniam, S; J. Struct. Biol., DOI://10.1016/j.jsb.2019.03.008 (2019)
Representation and relative abundance of cell-type selective markers in whole-kidney RNA-Seq data Clark, JZ; Chen, L; Chou, CL; Jung, HJ; Lee, JW; Knepper, MA; Kidney Int., DOI://10.1016/j.kint.2018.11.028 (2019)
Activity and structural analysis of GRL-117C: a novel small molecule CCR5 inhibitor active against R5-tropic HIV-1s Nakata, H; Maeda, K; Das, D et al. Sci Rep, DOI://10.1038/s41598-019-41080-w (2019)
Cloning and characterization of a novel aspartate/glutamate racemase from the acorn worm Saccoglossus kowalevskii Uda, K; Ishizuka, N; Edashige, Y; Kikuchi, A; Radkov, AD; Moe, LA; Comp. Biochem. Physiol. B, Biochem. Mol. Biol., DOI://10.1016/j.cbpb.2019.03.006 (2019)
S Values for neuroimaging procedures on Korean pediatric and adult head computational phantoms Villoing, D; Lee, AK; Choi, HD; Lee, C; Radiat Prot Dosimetry, DOI://10.1093/rpd/ncy287 (2019)
Inactivating Mutation in IRF8 Promotes Osteoclast Transcriptional Programs and Increases Susceptibility to Tooth Root Resorption Thumbigere-Math, V; Foster, BL; Bachu, M et al. J. Bone Miner. Res., DOI://10.1002/jbmr.3690 (2019)
Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine Tekola-Ayele, F; Lee, A; Workalemahu, T et al. Sci Rep, DOI://10.1038/s41598-019-40834-w (2019)

Accounting for random observation time in risk prediction with longitudinal markers: An imputation approach Han, Y; Liu, D; Stat Methods Med Res, DOI://10.1177/0962280219833089 (2019)
Synthesis and evaluation of two new candidate high-affinity full agonist PET radioligands for imaging 5-HT1B receptors Lindberg, A; Lu, S; Nag, S et al. Nucl. Med. Biol., DOI://10.1016/j.nucmedbio.2019.01.005 (2019)
An insight into the sialotranscriptome and virome of Amazonian anophelines Scarpassa, VM; Debat, HJ; Alencar, RB et al. BMC Genomics, DOI://10.1186/s12864-019-5545-0 (2019)
Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting Chauhan, G; Adams, HHH; Satizabal, CL et al. Neurology, DOI://10.1212/WNL.0000000000006851 (2019)
Isothermal Titration Calorimetry of Be2+ with Phosphatidylserine Models Guides All-Atom Force-Field Development for LipidIon Interactions Leonard, AN; Klauda, JB; Sukharev, S; J Phys Chem B, DOI://10.1021/acs.jpcb.8b11884 (2019)
Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses Kanekiyo, M; Joyce, MG; Gillespie, RA et al. Nat. Immunol., DOI://10.1038/s41590-018-0305-x (2019)
Dosimetric Impact of a New Computational Voxel Phantom Series for the Japanese Atomic Bomb Survivors: Children and Adults Griffin, K; Paulbeck, C; Bolch, W et al. Radiat. Res., DOI://10.1667/RR15267.1 (2019)
The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity Gautam, S; Fioravanti, J; Zhu, W et al. Nat. Immunol., DOI://10.1038/s41590-018-0311-z (2019)
Spatial Attention Deficits Are Causally Linked to an Area in Macaque Temporal Cortex Bogadhi, AR; Bollimunta, A; Leopold, DA; Krauzlis, RJ; Curr. Biol., DOI://10.1016/j.cub.2019.01.028 (2019)
Gustatory responses in macaque monkeys revealed with fMRI: Comments on taste, taste preference, and internal state Kaskan, PM; Dean, AM; Nicholas, MA; Mitz, AR; Murray, EA; Neuroimage, DOI://10.1016/j.neuroimage.2018.10.005 (2019)
Simultaneous targeting of linked loci in mouse embryos using base editing Lee, HK; Willi, M; Smith, HE et al. Sci Rep, DOI://10.1038/s41598-018-33533-5 (2019)
Molecular Dynamics Simulations of Membrane Permeability Venable, RM; Krämer, A; Pastor, RW; Chem. Rev., DOI://10.1021/acs.chemrev.8b00486 (2019)

Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration Ratnapriya, R; Sosina, OA; Starostik, MR et al. Nat. Genet., DOI://10.1038/s41588-019-0351-9 (2019)
Exome genotyping and linkage analysis identifies two novel linked regions and replicates two others for myopia in Ashkenazi Jewish families Simpson, CL; Musolf, AM; Li, Q et al. BMC Med. Genet., DOI://10.1186/s12881-019-0752-8 (2019)
Brain-wide cellular resolution imaging of Cre transgenic zebrafish lines for functional circuit-mapping Tabor, KM; Marquart, GD; Hurt, C et al. Elife, DOI://10.7554/eLife.42687 (2019)
Interpretation of spectroscopic data using molecular simulations for the secondary active transporter BetP Leone, V; Waclawska, I; Kossmann, K et al. J. Gen. Physiol., DOI://10.1085/jgp.201812111 (2019)
Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis Bandres-Ciga, S; Noyce, AJ; Hemani, G et al. Ann. Neurol., DOI://10.1002/ana.25431 (2019)
Whole Transcriptome Analysis of Renal Intercalated Cells Predicts Lipopolysaccharide Mediated Inhibition of Retinoid X Receptor alpha Function Saxena, V; Fitch, J; Ketz, J et al. Sci Rep, DOI://10.1038/s41598-018-36921-z (2019)

Distinct Clinical and Pathological Features of Melorheostosis Associated With Somatic MAP2K1 Mutations Jha, S; Fratzl-Zelman, N; Roschger, P et al. J. Bone Miner. Res., DOI://10.1002/jbmr.3577 (2019)
The prevalence of germline DICER1 pathogenic variation in cancer populations Kim, J; Schultz, KAP; Hill, DA; Stewart, DR; Mol Genet Genomic Med, DOI://10.1002/mgg3.555 (2019)
Sequence Variation Associated with SLC12A5 Gene Expression Is Linked to Brain Structure and Function in Healthy Adults Gregory, MD; Kippenhan, JS; Callicott, JH et al. Cereb. Cortex, DOI://10.1093/cercor/bhy344 (2019)
Structure and function of an ectopic Polycomb chromatin domain De, S; Cheng, Y; Sun, MA; Gehred, ND; Kassis, JA; Sci Adv, DOI://10.1126/sciadv.aau9739 (2019)
Interleukin-12 receptor β2 from grass carp: Molecular characterization and its involvement in Aeromonas hydrophila-induced intestinal inflammation Song, XH; Tang, J; Gao, TT et al. Fish Shellfish Immunol., DOI://10.1016/j.fsi.2019.01.016 (2019)
Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Epigenomic Program to Reduce Allergic Pathology Schwartz, DM; Farley, TK; Richoz, N et al. Immunity, DOI://10.1016/j.immuni.2018.12.014 (2019)

A conserved dimer interface connects ERH and YTH family proteins to promote gene silencing Xie, G; Vo, TV; Thillainadesan, G et al. Nat Commun, DOI://10.1038/s41467-018-08273-9 (2019)
The Emergence and Functional Fitness of Memory CD4+ T Cells Require the Transcription Factor Thpok Ciucci, T; Vacchio, MS; Gao, Y et al. Immunity, DOI://10.1016/j.immuni.2018.12.019 (2019)
The mitochondrial type IB topoisomerase drives mitochondrial translation and carcinogenesis Baechler, SA; Factor, VM; Dalla Rosa, I et al. Nat Commun, DOI://10.1038/s41467-018-07922-3 (2019)
Levels of early-childhood behavioral inhibition predict distinct neurodevelopmental pathways to pediatric anxiety Abend, R; Swetlitz, C; White, LK et al. Psychol Med, DOI://10.1017/S0033291718003999 (2019)
The phenotypic landscape of a Tbc1d24 mutant mouse includes convulsive seizures resembling human early infantile epileptic encephalopathy Tona, R; Chen, W; Nakano, Y et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddy445 (2019)
Secondary Metabolites from the Fungus Dictyosporium sp. and Their MALT1 Inhibitory Activities Tran, TD; Wilson, BAP; Henrich, CJ et al. J. Nat. Prod., DOI://10.1021/acs.jnatprod.8b00871 (2019)

Interface-Based Structural Prediction of Novel Host-Pathogen Interactions Guven-Maiorov, E; Tsai, CJ; Ma, B; Nussinov, R; Methods Mol. Biol., DOI://10.1007/978-1-4939-8736-8_18 (2019)

2018 (425 papers)

Agreement in Histological Assessment of Mitotic Activity Between Microscopy and Digital Whole Slide Images Informs Conversion for Clinical Diagnosis Wei, BR; Halsey, CH; Hoover, SB et al. Acad Pathol, DOI://10.1177/2374289519859841 (2018)
Using Devices to Assess Physical Activity and Sedentary Behavior in a Large Cohort Study, the Women's Health Study Lee, IM; Shiroma, EJ; Evenson, KR; Kamada, M; LaCroix, AZ; Buring, JE; J Meas Phys Behav, DOI://10.1123/jmpb.2018-0005 (2018)
Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells Mudd, JC; Busman-Sahay, K; DiNapoli, SR et al. Nat Commun, DOI://10.1038/s41467-018-05528-3 (2018)
GWAS of epigenetic aging rates in blood reveals a critical role for TERT Lu, AT; Xue, L; Salfati, EL et al. Nat Commun, DOI://10.1038/s41467-017-02697-5 (2018)
Human retinoic acid-regulated CD161+ regulatory T cells support wound repair in intestinal mucosa Povoleri, GAM; Nova-Lamperti, E; Scottà, C et al. Nat. Immunol., DOI://10.1038/s41590-018-0230-z (2018)

Genome-wide Identification of Structure-Forming Repeats as Principal Sites of Fork Collapse upon ATR Inhibition Shastri, N; Tsai, YC; Hile, S et al. Mol. Cell, DOI://10.1016/j.molcel.2018.08.047 (2018)
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation Teumer, A; Chaker, L; Groeneweg, S et al. Nat Commun, DOI://10.1038/s41467-018-06356-1 (2018)
Dynamic analysis of human tyrosinase intra-melanosomal domain and mutant variants to further understand oculocutaneous albinism type 1 Farney, SK; Dolinska, MB; Sergeev, YV; J Anal Pharm Res, DOI://10.15406/japlr.2018.07.00293 (2018)
Conserved mRNA-granule component Scd6 targets Dhh1 to repress translation initiation and activates Dcp2-mediated mRNA decay in vivo Zeidan, Q; He, F; Zhang, F; Zhang, H; Jacobson, A; Hinnebusch, AG; PLoS Genet., DOI://10.1371/journal.pgen.1007806 (2018)
Intraclass correlation: Improved modeling approaches and applications for neuroimaging Chen, G; Taylor, PA; Haller, SP et al. Hum Brain Mapp, DOI://10.1002/hbm.23909 (2018)
Decrypting the Heat Activation Mechanism of TRPV1 Channel by Molecular Dynamics Simulation Wen, H; Zheng, W; Biophys. J., DOI://10.1016/j.bpj.2017.10.034 (2018)

Re-annotation of eight Drosophila genomes Yang, H; Jaime, M; Polihronakis, M et al. Life Sci Alliance, DOI://10.26508/lsa.201800156 (2018)
Patterns of Physical Activity and Sedentary Behavior for Older Adults with Alzheimer's Disease, Mild Cognitive Impairment, and Cognitively Normal in Hong Kong Lu, Z; Harris, TB; Shiroma, EJ; Leung, J; Kwok, T; J. Alzheimers Dis., DOI://10.3233/JAD-180805 (2018)
A small single-domain protein folds through the same pathway on and off the ribosome Guinn, EJ; Tian, P; Shin, M; Best, RB; Marqusee, S; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1810517115 (2018)
Metabolic remodelling of glucose, fatty acid and redox pathways in the heart of type 2 diabetic mice Cortassa, S; Caceres, V; Tocchetti, CG et al. J. Physiol. (Lond.), DOI://10.1113/JP276824 (2018)
Dose coefficients of mesh-type ICRP reference computational phantoms for idealized external exposures of photons and electrons Yeom YS; Choi C; et al Nuclear Engineering and Technology, doi://10.1016/j.net.2018.12.006 (2018)
The shape of the bacterial ribosome exit tunnel affects cotranslational protein folding Kudva, R; Tian, P; Pardo-Avila, F et al. Elife, DOI://10.7554/eLife.36326 (2018)

On the convergence of multi-scale free energy simulations König, G; Brooks, BR; Thiel, W; York, DM; Mol Simul, DOI://10.1080/08927022.2018.1475741 (2018)
Investigation of a Cluster of Sphingomonas koreensis Infections Johnson, RC; Deming, C; Conlan, S et al. N. Engl. J. Med., DOI://10.1056/NEJMoa1803238 (2018)
Hydrogen-bond dependent conformational switching: a computational challenge from experimental thermochemistry Luccarelli, J; Paton, RS; J. Org. Chem., DOI://10.1021/acs.joc.8b02436 (2018)
Intrinsic Dynamics of a Human Gene Reveal the Basis of Expression Heterogeneity Rodriguez, J; Ren, G; Day, CR; Zhao, K; Chow, CC; Larson, DR; Cell, DOI://10.1016/j.cell.2018.11.026 (2018)
Prevalence of pathogenic/likely pathogenic variants in the 24 cancer genes of the ACMG Secondary Findings v2.0 list in a large cancer cohort and ethnicity-matched controls Kim, J; Luo, W; Wang, M et al. Genome Med, DOI://10.1186/s13073-018-0607-5 (2018)
A dysbiotic microbiome triggers TH17 cells to mediate oral mucosal immunopathology in mice and humans Nicolas Dutzan, Tetsuhiro Kajikawa, Loreto Abusleme et al. Mucosal Immunity, 10.1126/scitranslmed.aat0797 (2018)

Amyloid Fibril Design: Limiting Structural Polymorphism in Alzheimer's Aβ Protofilaments Bartomiej Tywoniuk, Ye Yuan, Sarah McCartan, Beata Maria Szyd&#;owska, Florentina Tofoleanu, Bernard R. Brooks, and Nicolae-Viorel Buchete J. Phys. Chem B, 10.1021/acs.jpcb.8b07423 (2018)
Probing the hras-1Y i-motif with small molecules Sara N. Journey, Stephanie L. Alden, Will M. Hewitt, Megan L. Peach, Marc C. Nicklaus and John S. Schneekloth Jr Med. Chem. Commun.,, 10.1039/C8MD00311D (2018)
Renal compartment-specific genetic variation analyses identify new pathways in chronic kidney disease Qiu, C; Huang, S; Park, J et al. Nat. Med., DOI://10.1038/s41591-018-0194-4 (2018)
Finding the baby in the bath water - evidence for task-specific changes in resting state functional connectivity evoked by training Steel, A; Thomas, C; Trefler, A; Chen, G; Baker, CI; Neuroimage, DOI://10.1016/j.neuroimage.2018.12.038 (2018)
Dynamic transcriptome profiling dataset of vaccinia virus obtained from long-read sequencing techniques Tombácz, D; Prazsák, I; Szucs, A; Dénes, B; Snyder, M; Boldogkoi, Z; Gigascience, DOI://10.1093/gigascience/giy139 (2018)
From Molecules to Mechanisms: Functional Proteomics and Its Application to Renal Tubule Physiology Rinschen, MM; Limbutara, K; Knepper, MA; Payne, DM; Pisitkun, T; Physiol. Rev., DOI://10.1152/physrev.00057.2017 (2018)

RNA-Protein Interactions Prevent Long RNA Duplex Formation: Implications for the Design of RNA-Based Therapeutics Bindewald, E; Dai, L; Kasprzak, WK; Kim, T; Gu, S; Shapiro, BA; Molecules, DOI://10.3390/molecules23123329 (2018)
In Silico Mutagenesis: Decreasing the Immunogenicity of Botulinum Toxin Type A Evander Emeltan Tjoa, S; Maria Vianney, Y; Emantoko Dwi Putra, S; J. Biomol. Struct. Dyn., DOI://10.1080/07391102.2018.1559100 (2018)
A Divergent Strain of Culex pipiens-Associated Tunisia Virus in the Malaria Vector Anopheles epiroticus Debat, HJ; Ribeiro, JMC; Microbiol Resour Announc, DOI://10.1128/MRA.01026-18 (2018)
The Inner Ear Heat Shock Transcriptional Signature Identifies Compounds That Protect Against Aminoglycoside Ototoxicity Ryals, M; Morell, RJ; Martin, D et al. Front Cell Neurosci, DOI://10.3389/fncel.2018.00445 (2018)
A versatile mouse model of epitope-tagged histone H3.3 to study epigenome dynamics Bachu, M; Tamura, T; Chen, C et al. J. Biol. Chem., DOI://10.1074/jbc.RA118.005550 (2018)
Genetic analysis of neurodegenerative diseases in a pathology cohort Blauwendraat C, Pletnikova O, Geiger, JT et al Neurobiology of Aging, 10.1016/j.neurobiolaging.2018.11.007 (2018)

Metagenomic Discovery of 83 New Human Papillomavirus Types in Patients with Immunodeficiency Pastrana, DV; Peretti, A; Welch, NL et al. mSphere, DOI://10.1128/mSphereDirect.00645-18 (2018)
Conformational stability and dynamics of the cancer-associated isoform Δ133p53β are modulated by p53 peptides and p53-specific DNA Lei, J; Qi, R; Tang, Y et al. FASEB J., DOI://10.1096/fj.201801973R (2018)
Persistent upregulation of the β-tubulin tubb6, linked to muscle regeneration, is a source of microtubule disorganization in dystrophic muscle Randazzo, D; Khalique, U; Belanto, JJ et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddy418 (2018)
hnRNP L-dependent protection of normal mRNAs from NMD subverts quality control in B cell lymphoma Kishor, A; Ge, Z; Hogg, JR; EMBO J., DOI://10.15252/embj.201899128 (2018)
Structural Characterization of Biomolecules through Atomistic Simulations Guided by DEER Measurements Marinelli, F; Fiorin, G; Structure, DOI://10.1016/j.str.2018.10.013 (2018)
Linear mixed models for association analysis of quantitative traits with next-generation sequencing data Chiu, CY; Yuan, F; Zhang, BS et al. Genet. Epidemiol., DOI://10.1002/gepi.22177 (2018)

Peptidylarginine deiminases 2 and 4 modulate innate and adaptive immune responses in TLR-7-dependent lupus Liu, Y; Lightfoot, YL; Seto, N et al. JCI Insight, DOI://10.1172/jci.insight.124729 (2018)
A temporal deconvolution algorithm for multiecho functional MRI Cesar Caballero Gaudes ; Peter A. Bandettini ; Javier Gonzalez-Castillo 2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018), 10.1109/ISBI.2018.8363649 (2018)
Folding pathway of an Ig domain is conserved on and off the ribosome Tian, P; Steward, A; Kudva, R et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1810523115 (2018)
Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury Harrison, OJ; Linehan, JL; Shih, HY et al. Science, DOI://10.1126/science.aat6280 (2018)
Mosaic Y loss is moderately associated with solid tumor risk Loftfield, E; Zhou, W; Yeager, M; Chanock, SJ; Freedman, ND; Machiela, MJ; Cancer Res., DOI://10.1158/0008-5472.CAN-18-2566 (2018)
AbDesigner3D: a structure-guided tool for peptide-based antibody production Saethang, T; Hodge, K; Kimkong, I; Payne, DM; Knepper, MA; Pisitkun, T; Bioinformatics, DOI://10.1093/bioinformatics/bty055 (2018)

Helios is a key transcriptional regulator of outer hair cell maturation Chessum, L; Matern, MS; Kelly, MC et al. Nature, DOI://10.1038/s41586-018-0728-4 (2018)
Whole-genome sequencing of 175 Mongolians uncovers population-specific genetic architecture and gene flow throughout North and East Asia Bai, H; Guo, X; Narisu, N et al. Nat. Genet., DOI://10.1038/s41588-018-0250-5 (2018)
Comparing the performance of selected variant callers using synthetic data and genome segmentation Bian, X; Zhu, B; Wang, M et al. BMC Bioinformatics, DOI://10.1186/s12859-018-2440-7 (2018)
Proximity-CLIP provides a snapshot of protein-occupied RNA elements in subcellular compartments Benhalevy, D; Anastasakis, DG; Hafner, M; Nat. Methods, DOI://10.1038/s41592-018-0220-y (2018)
Direct observation of topoisomerase IA gate dynamics Mills, M; Tse-Dinh, YC; Neuman, KC; Nat. Struct. Mol. Biol., DOI://10.1038/s41594-018-0158-x (2018)
An integrative systems biology approach for precision medicine in diabetic kidney disease Mulder, S; Hamidi, H; Kretzler, M; Ju, W; Diabetes Obes Metab, DOI://10.1111/dom.13416 (2018)

Acetylation of Cytidine in mRNA Promotes Translation Efficiency Arango, D; Sturgill, D; Alhusaini, N et al. Cell, DOI://10.1016/j.cell.2018.10.030 (2018)
TRPV1 pore turret dictates distinct DkTx and capsaicin gating Geron, M; Kumar, R; Zhou, W; Faraldo-Gómez, JD; Vásquez, V; Priel, A; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1809662115 (2018)
How to fold and protect mitochondrial ribosomal RNA with fewer guanines Hosseini, M; Roy, P; Sissler, M; Zirbel, CL; Westhof, E; Leontis, N; Nucleic Acids Res., DOI://10.1093/nar/gky762 (2018)
Influence of Fetal and Maternal Genetic Susceptibility to Obesity on Birthweight in African Ancestry Populations Shrestha, D; Rahman, ML; Workalemahu, T; Zhu, C; Tekola-Ayele, F; Front Genet, DOI://10.3389/fgene.2018.00511 (2018)
Mutational and Phenotypic Spectra of KCNE1 deficiency in Jervell and Lange-Nielsen Syndrome and Romano-Ward Syndrome Faridi, R; Tona, R; Brofferio, A et al. Hum. Mutat., DOI://10.1002/humu.23689 (2018)
Self-adaptive multiscaling algorithm for efficient simulations of many-protein systems in crowded conditions Hassan, SA Phys Chem Chem Phys, DOI://10.1039/c8cp05517c (2018)

hsegHMM: hidden Markov model-based allele-specific copy number alteration analysis accounting for hypersegmentation Choo-Wosoba, H; Albert, PS; Zhu, B; BMC Bioinformatics, DOI://10.1186/s12859-018-2412-y (2018)
Characterization of spatial and temporal development of Type I and Type II hair cells in the mouse utricle using new cell-type-specific markers McInturff, S; Burns, JC; Kelley, MW; Biol Open, DOI://10.1242/bio.038083 (2018)
Single-cell RNA sequencing of the mammalian pineal gland identifies two pinealocyte subtypes and cell type-specific daily patterns of gene expression Mays, JC; Kelly, MC; Coon, SL et al. PLoS ONE, DOI://10.1371/journal.pone.0205883 (2018)
HJURP antagonizes CENP-A mislocalization driven by the H3.3 chaperones HIRA and DAXX Nye, J; Sturgill, D; Athwal, R; Dalal, Y; PLoS ONE, DOI://10.1371/journal.pone.0205948 (2018)
Current progress and future opportunities in applications of bioinformatics for biodefense and pathogen detection: report from the Winter Mid-Atlantic Microbiome Meet-up, College Park, MD, January 10, 2018 Meisel, JS; Nasko, DJ; Brubach, B et al. Microbiome, DOI://10.1186/s40168-018-0582-5 (2018)
Targeted deletion of an NRL- and CRX-regulated alternative promoter specifically silences FERM and PDZ domain containing 1 (Frmpd1) in rod photoreceptors Campla, CK; Mast, H; Dong, L et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddy388 (2018)
Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination Steklov, M; Pandolfi, S; Baietti, MF et al. Science, DOI://10.1126/science.aap7607 (2018)
The effect of repeated stimulated granulocyte donations on hematopoietic indexes in donors: a 24-year donor center experience Szymanski, J; Troendle, J; Leitman, S; Hong, H; Yau, YY; Cantilena, C; Transfusion, DOI://10.1111/trf.15000 (2018)
Mechanism of FACT removal from transcribed genes by anticancer drugs curaxins Chang, HW; Valieva, ME; Safina, A et al. Sci Adv, DOI://10.1126/sciadv.aav2131 (2018)
Quantifying differences between passive and task-evoked intrinsic functional connectivity in a large-scale brain simulation Ulloa, A; Horwitz, B; Brain Connect, DOI://10.1089/brain.2018.0620 (2018)
Transcriptome signature for dietary fructose-specific changes in rat renal cortex: A quantitative approach to physiological relevance Gonzalez-Vicente, A; Garvin, JL; Hopfer, U; PLoS ONE, DOI://10.1371/journal.pone.0201293 (2018)
High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping Czerniecki, SM; Cruz, NM; Harder, JL et al. Cell Stem Cell, DOI://10.1016/j.stem.2018.04.022 (2018)

A Comparison of QM/MM Simulations with and without the Drude Oscillator Model Based on Hydration Free Energies of Simple Solutes König, G; Pickard, FC; Huang, J et al. Molecules, DOI://10.3390/molecules23102695 (2018)
--Mitochondrial ATP synthase dimers spontaneously associate due to a long-range membrane-induced force Anselmi, C; Davies, KM; Faraldo-Gómez, JD; J. Gen. Physiol., DOI://10.1085/jgp.201812033 (2018)
Collecting duct principal, but not intercalated, cell prorenin receptor regulates renal sodium and water excretion Ramkumar, N; Stuart, D; Mironova, E et al. Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00122.2018 (2018)
RNA sequencing of kidney distal tubule cells reveals multiple mediators of chronic aldosterone action Poulsen, SB; Limbutara, K; Fenton, RA; Pisitkun, T; Christensen, BM; Physiol. Genomics, DOI://10.1152/physiolgenomics.00084.2017 (2018)
Approaches to the discovery of non-invasive urinary biomarkers of prostate cancer Jedinak, A; Loughlin, KR; Moses, MA; Oncotarget, DOI://10.18632/oncotarget.25946 (2018)
Sequence-based searching of custom proteome and transcriptome databases Medvar, B; Sarkar, A; Knepper, M; Pisitkun, T; Physiol Rep, DOI://10.14814/phy2.13846 (2018)
BRG1 governs glucocorticoid receptor interactions with chromatin and pioneer factors across the genome Hoffman, JA; Trotter, KW; Ward, JM; Archer, TK; Elife, DOI://10.7554/eLife.35073 (2018)
Amycomicin is a potent and specific antibiotic discovered with a targeted interaction screen Pishchany, G; Mevers, E; Ndousse-Fetter, S et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1807613115 (2018)
JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies Sanchez, GAM; Reinhardt, A; Ramsey, S et al. J. Clin. Invest., DOI://10.1172/JCI98814 (2018)
Mitochondrial chaotic dynamics: Redox-energetic behavior at the edge of stability Kembro, JM; Cortassa, S; Lloyd, D; Sollott, SJ; Aon, MA; Sci Rep, DOI://10.1038/s41598-018-33582-w (2018)
A function-blocking CD47 antibody modulates extracellular vesicle-mediated intercellular signaling between breast carcinoma cells and endothelial cells Kaur, S; Elkahloun, AG; Singh, SP; Arakelyan, A; Roberts, DD; J Cell Commun Signal, DOI://10.1007/s12079-017-0428-0 (2018)
Statistics for Immunologists Curr Protoc Immunol, 1934-368X (2018)

Practical issues in using generalized estimating equations for inference on transitions in longitudinal data: What is being estimated Bible, J; Albert, PS; Simons-Morton, BG; Liu, D; Stat Med, DOI://10.1002/sim.8014 (2018)
Whole-exome sequencing of nevoid basal cell carcinoma syndrome families and review of Human Gene Mutation Database PTCH1 mutation data Gianferante, DM; Rotunno, M; Dean, M et al. Mol Genet Genomic Med, DOI://10.1002/mgg3.498 (2018)
Renal release of Ac-SDKP is part of an antifibrotic peptidergic system in the kidney Romero, CA; Kumar, N; Nakagawa, P et al. Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00270.2018 (2018)
Expanded skin virome in DOCK8-deficient patients Tirosh, O; Conlan, S; Deming, C et al. Nat. Med., DOI://10.1038/s41591-018-0211-7 (2018)
Nuclear Transcriptomes of the Seven Neuronal Cell Types That Constitute the Drosophila Mushroom Bodies Shih, MM; Davis, FP; Henry, GL; Dubnau, J; G3 (Bethesda), DOI://10.1534/g3.118.200726 (2018)
A fast adaptive algorithm for computing whole-genome homology maps Chirag Jain, Sergey Koren, Alexander Dilthey, Adam M Phillippy, and Srinivas Aluru Bioinformatics, doi://10.1093/bioinformatics/bty597 (2018)

Integrated Epigenetic Mapping of Human and Mouse Salivary Gene Regulation Michael, DG; Pranzatelli, TJF; Warner, BM; Yin, H; Chiorini, JA; J. Dent. Res., DOI://10.1177/0022034518806518 (2018)
Clonal expansion and compartmentalized maintenance of rhesus macaque NK cell subsets Wu, C; Espinoza, DA; Koelle, SJ et al. Sci Immunol, DOI://10.1126/sciimmunol.aat9781 (2018)
RefSeq database growth influences the accuracy of k-mer-based lowest common ancestor species identification Nasko, DJ; Koren, S; Phillippy, AM; Treangen, TJ; Genome Biol., DOI://10.1186/s13059-018-1554-6 (2018)
Non-canonical Drosophila X chromosome dosage compensation and repressive topologically associated domains Lee, H; Oliver, B; Epigenetics Chromatin, DOI://10.1186/s13072-018-0232-y (2018)
Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke Cole, JW; Xu, H; Ryan, K et al. PLoS ONE, DOI://10.1371/journal.pone.0206554 (2018)
Genomic and Transcriptomic Characterization Links Cell Lines with Aggressive Head and Neck Cancers Cheng, H; Yang, X; Si, H et al. Cell Rep, DOI://10.1016/j.celrep.2018.10.007 (2018)

Body-weight dependent dose coefficients for adults exposed to idealised external photon fields Lienard A Chang David Borrego and Choonsik Lee J. Radiological Protection, vol 38, no 4 (2018)
Organ Dose Estimation accounting for uncertainty for pediatric and young adult CT scans in the United Kingdom Lee, C; Journy, N; Moroz, BE et al. Radiat Prot Dosimetry, DOI://10.1093/rpd/ncy184 (2018)
Molecular Determinants of Aβ42 Adsorption to Amyloid Fibril Surfaces Bellaiche, MMJ; Best, RB; J Phys Chem Lett, DOI://10.1021/acs.jpclett.8b02375 (2018)
Argonaute2 attenuates active transcription by limiting RNA Polymerase II elongation in Drosophila melanogaster Nazer, E; Dale, RK; Palmer, C; Lei, EP; Sci Rep, DOI://10.1038/s41598-018-34115-1 (2018)
Enhanced expression and distinctive characterization of a long-acting FGF21 and its potential to alleviate nonalcoholic steatohepatitis Yin, J; Bao, L; Chen, R; Gao, W; Gao, X; Yao, W; Biochimie, DOI://10.1016/j.biochi.2018.05.020 (2018)
Brain regions modulated during covert visual attention in the macaque Bogadhi, AR; Bollimunta, A; Leopold, DA; Krauzlis, RJ; Sci Rep, DOI://10.1038/s41598-018-33567-9 (2018)
Variable population prevalence estimates of germline TP53 variants: A gnomAD-based analysis de Andrade, KC; Frone, MN; Wegman-Ostrosky, T et al. Hum. Mutat., DOI://10.1002/humu.23673 (2018)
De novo assembly of haplotype-resolved genomes with trio binning Koren, S; Rhie, A; Walenz, BP et al. Nat. Biotechnol., DOI://10.1038/nbt.4277 (2018)
Structural interpretation of DNA-protein hydroxyl-radical footprinting experiments with high resolution using HYDROID Shaytan, AK; Xiao, H; Armeev, GA et al. Nat Protoc, DOI://10.1038/s41596-018-0048-z (2018)
Cell-type-specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes Zhang, T; Choi, J; Kovacs, MA et al. Genome Res., DOI://10.1101/gr.233304.117 (2018)
Peptide-MHC (pMHC) binding to a human antiviral T cell receptor induces long-range allosteric communication between pMHC- and CD3-binding sites Rangarajan, S; He, Y; Chen, Y et al. J. Biol. Chem., DOI://10.1074/jbc.RA118.003832 (2018)
Molecular Recognition between Aβ-Specific Single-Domain Antibody and Aβ Misfolded Aggregates Mingzhen Zhang, Jie Zheng, Ruth Nussinov and Buyong Ma Antibodies, doi:10.3390/antib7030025 (2018)

Comparison of the umbrella sampling and the double decoupling method in binding free energy predictions for SAMPL6 octa-acid host-guest challenges Nishikawa, N; Han, K; Wu, X; Tofoleanu, F; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-018-0166-2 (2018)
Single-Molecule Analysis Reveals Linked Cycles of RSC Chromatin Remodeling and Ace1p Transcription Factor Binding in Yeast Mehta, GD; Ball, DA; Eriksson, PR et al. Mol. Cell, DOI://10.1016/j.molcel.2018.09.009 (2018)
Optimizing and evaluating biomarker combinations as trial-level general surrogates Gabriel, EE; Sachs, MC; Daniels, MJ; Halloran, ME; Stat Med, DOI://10.1002/sim.7996 (2018)
Global genetic insight contributed by consanguineous Pakistani families segregating hearing loss Richard, EM; Santos-Cortez, RL; Faridi, R et al. Hum. Mutat., DOI://10.1002/humu.23666 (2018)
Accelerating QM/MM Free Energy Computations via Intramolecular Force Matching Hudson, PS; Boresch, S; Rogers, DM; Woodcock, HL; J Chem Theory Comput, DOI://10.1021/acs.jctc.8b00517 (2018)
Loss of functional connectivity is an early imaging marker in primary lateral sclerosis Clark, MG; Smallwood Shoukry, R; Huang, CJ; Danielian, LE; Bageac, D; Floeter, MK; Amyotroph Lateral Scler Frontotemporal Degener, DOI://10.1080/21678421.2018.1517180 (2018)

QuagmiR: A Cloud-based Application for IsomiR Big Data Analytics Bofill-De Ros, X; Chen, K; Chen, S et al. Bioinformatics, DOI://10.1093/bioinformatics/bty843 (2018)
Estimating onset time from longitudinal data in the presence of measurement error with application to estimating gestational age from maternal anthropometry during pregnancy Ortega-Villa, AM; Albert, PS; Stat Med, DOI://10.1002/sim.7955 (2018)
CRISPro: An Automated Pipeline for Protein Conformation Stabilization by Proline Rawi, R; Shen, CH; Kwong, PD; Chuang, GY; J Chem Inf Model, DOI://10.1021/acs.jcim.8b00592 (2018)
Impact of induced anxiety on neural responses to monetary incentives Gorka, AX; Fuchs, B; Grillon, C; Ernst, M; Soc Cogn Affect Neurosci, DOI://10.1093/scan/nsy082 (2018)
Antigen binding allosterically promotes Fc receptor recognition Zhao, J; Nussinov, R; Ma, B; MAbs, DOI://10.1080/19420862.2018.1522178 (2018)
Progressing super-enhancer landscape during mammary differentiation controls tissue-specific gene regulation Lee, HK; Willi, M; Shin, HY; Liu, C; Hennighausen, L; Nucleic Acids Res., DOI://10.1093/nar/gky891 (2018)
Early life disadvantage and adult adiposity: tests of sensitive periods during childhood and behavioural mediation in adulthood Gilman, SE; Huang, YT; Jimenez, MP et al. Int J Epidemiol, DOI://10.1093/ije/dyy199 (2018)
An explicit-solvent hybrid QM and MM approach for predicting pKa of small molecules in SAMPL6 challenge Prasad, S; Huang, J; Zeng, Q; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-018-0167-1 (2018)
Origin of Internal Friction in Disordered Proteins Depends on Solvent Quality Zheng, W; Hofmann, H; Schuler, B; Best, RB; J Phys Chem B, DOI://10.1021/acs.jpcb.8b07425 (2018)
Force matching as a stepping stone to QM/MM CB[8] host/guest binding free energies: a SAMPL6 cautionary tale Hudson, PS; Han, K; Woodcock, HL; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-018-0165-3 (2018)
Mutation frequency is not increased in CRISPR-Cas9-edited mice Willi, M; Smith, HE; Wang, C; Liu, C; Hennighausen, L; Nat. Methods, DOI://10.1038/s41592-018-0148-2 (2018)
A Bayesian multi-dimensional couple-based latent risk model with an application to infertility Hwang, BS; Chen, Z; Louis, GMB; Albert, PS; Biometrics, DOI://10.1111/biom.12972 (2018)

Nutrient-Driven O-GlcNAcylation at Promoters Impacts Genome-Wide RNA Pol II Distribution Krause, MW; Love, DC; Ghosh, SK et al. Front Endocrinol (Lausanne), DOI://10.3389/fendo.2018.00521 (2018)
Evidence for the critical role of transmembrane helices 1 and 7 in substrate transport by human P-glycoprotein (ABCB1) Sajid, A; Lusvarghi, S; Chufan, EE; Ambudkar, SV; PLoS ONE, DOI://10.1371/journal.pone.0204693 (2018)
Visualization and Interpretation of Convolutional Neural Network Predictions in Detecting Pneumonia in Pediatric Chest Radiographs S. Rajaraman, S. Candemir, I. Kim, G. Thoma, S. Antani Appl. Sci. , doi://10.3390/app8101715 (2018)
Genetic history of Chad Shriner, D; Rotimi, CN; Am. J. Phys. Anthropol., DOI://10.1002/ajpa.23711 (2018)
Principles of nucleosome organization revealed by single-cell micrococcal nuclease sequencing Lai, B; Gao, W; Cui, K et al. Nature, DOI://10.1038/s41586-018-0567-3 (2018)
Identifying core biological processes distinguishing human eye tissues with precise systems-level gene expression analyses and weighted correlation networks Bryan, JM; Fufa, TD; Bharti, K; Brooks, BP; Hufnagel, RB; McGaughey, DM; Hum. Mol. Genet., DOI://10.1093/hmg/ddy239 (2018)

Structural elements required for coupling ion and substrate transport in the neurotransmitter transporter homolog LeuT Zhang, YW; Tavoulari, S; Sinning, S; Aleksandrova, AA; Forrest, LR; Rudnick, G; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1716870115 (2018)
Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia Kim, MY; Yu, KR; Kenderian, SS et al. Cell, DOI://10.1016/j.cell.2018.05.013 (2018)
Extensive sex differences at the initiation of genetic recombination Brick, K; Thibault-Sennett, S; Smagulova, F et al. Nature, DOI://10.1038/s41586-018-0492-5 (2018)
Transcriptional outcomes and kinetic patterning of gene expression in response to NF-κB activation Zhao, M; Joy, J; Zhou, W et al. PLoS Biol., DOI://10.1371/journal.pbio.2006347 (2018)
Whole genome sequencing data for two individuals of Pakistani descent Khan, SY; Kabir, F; M'Hamdi, O et al. Sci Data, DOI://10.1038/sdata.2018.174 (2018)
Peptide and Protein Structure Prediction with a Simplified Continuum Solvent Model Steinbach, PJ J Phys Chem B, DOI://10.1021/acs.jpcb.8b07264 (2018)
Proteomic approaches in kidney disease biomarker discovery Wu, Q; Fenton, RA; Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00421.2018 (2018)
Relation between single-molecule properties and phase behavior of intrinsically disordered proteins Dignon, GL; Zheng, W; Best, RB; Kim, YC; Mittal, J; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1804177115 (2018)
Robust Hund rule without Coulomb repulsion and exclusion principle in quantum antiferromagnetic chains of composite half spins Duki, SF; Yu, YK; J Phys Condens Matter, DOI://10.1088/1361-648X/aae169 (2018)
Random forest based classification of alcohol dependence patients and healthy controls using resting state MRI Zhu, X; Du, X; Kerich, M; Lohoff, FW; Momenan, R; Neurosci. Lett., DOI://10.1016/j.neulet.2018.04.007 (2018)
Half blind superiority tests for clinical trials of anti-infective drugs Follmann, D; Brittain, E; Lumbard, K; Stat Med, DOI://10.1002/sim.7954 (2018)
A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A Ciftci-Yilmaz, S; Au, WC; Mishra, PK et al. Genetics, DOI://10.1534/genetics.118.301305 (2018)

DNA methylation age is accelerated in alcohol dependence Rosen, AD; Robertson, KD; Hlady, RA et al. Transl Psychiatry, DOI://10.1038/s41398-018-0233-4 (2018)
Dynamics of Genome Alterations in Crohn's Disease-Associated Colorectal Carcinogenesis Hirsch, D; Wangsa, D; Zhu, YJ et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-0630 (2018)
EWS-FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine-glycine biosynthesis Sen, N; Cross, AM; Lorenzi, PL et al. Mol. Carcinog., DOI://10.1002/mc.22849 (2018)
Time-varying whole-brain functional network connectivity coupled to task engagement Hua X, Gonzalez-Castillo J, Handwerker D, Bandettini P Network Neuro Science, doi://10.1162/netn_a_00051 (2018)
Prediction of CB[8] host-guest binding free energies in SAMPL6 using the double-decoupling method Han K, Hudson PS, Jones MR et al J. Comp-Aided Mol. Des., doi:///10.1007/s10822-018-0144-8 (2018)
Conformational Dynamics of Chromatin Fibers: Comparison of Monte Carlo Simulations with Force Spectroscopy Davood Norouzi, Victor B.Zhurkin Biophysical J. , doi://10.1016/j.bpj.2018.06.032 (2018)

Designing deep neural networks to automate segmentation for serial block-face electron microscopy Matthew Guay ; Zeyad Emam ; Adam Anderson ; Richard Leapman 2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018), doi://10.1109/ISBI.2018.8363603 (2018)
Multiple claudin-claudin cis interfaces are required for tight junction strand formation and inherent flexibility Zhao, J; Krystofiak, ES; Ballesteros A et al. Comm. Biol. , doi://10.1038/s42003-018-0051-5 (2018)
Calmodulin (CaM) Activates PI3Kα by Targeting the "Soft" CaM-Binding Motifs in Both the nSH2 and cSH2 Domains of p85α Zhang M, Li Z, Wang G et al. J. Phys. Chem B, doi://10.1021/acs.jpcb.8b05982 (2018)
Functional and physical interaction between yeast Hsp90 and Hsp70 Kravats, AN; Hoskins, JR; Reidy, M et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1719969115 (2018)
Aneuploidy, TP53 mutation, and amplification of MYC correlate with increased intratumor heterogeneity and poor prognosis of breast cancer patients Oltmann, J; Heselmeyer-Haddad, K; Hernandez, LS et al. Genes Chromosomes Cancer, DOI://10.1002/gcc.22515 (2018)
Neurophysiological Changes Associated with Antidepressant Response to Ketamine Not Observed in a Negative Trial of Scopolamine in Major Depressive Disorder Park, L; Furey, M; Nugent, AC et al. Int. J. Neuropsychopharmacol., DOI://10.1093/ijnp/pyy051 (2018)

The High Genetic Barrier of EFdA/MK-8591 Stems from Strong Interactions with the Active Site of Drug-Resistant HIV-1 Reverse Transcriptase Takamatsu, Y; Das, D; Kohgo, S et al. Cell Chem Biol, DOI://10.1016/j.chembiol.2018.07.014 (2018)
Mapping discontinuous epitopes for MRK-16, UIC2 and 4E3 antibodies to extracellular loops 1 and 4 of human P-glycoprotein Vahedi, S; Lusvarghi, S; Pluchino, K et al. Sci Rep, DOI://10.1038/s41598-018-30984-8 (2018)
Trac-looping measures genome structure and chromatin accessibility Lai, B; Tang, Q; Jin, W et al. Nat. Methods, DOI://10.1038/s41592-018-0107-y (2018)
Heterogeneity of calcium clock functions in dormant, dysrhythmically and rhythmically firing single pacemaker cells isolated from SA node Kim, MS; Maltsev, AV; Monfredi, O et al. Cell Calcium, DOI://10.1016/j.ceca.2018.07.002 (2018)
Targeted RNA-sequencing for the quantification of measurable residual disease in acute myeloid leukemia Dillon, LW; Hayati, S; Roloff, GW et al. Haematologica, DOI://10.3324/haematol.2018.203133 (2018)
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure Sung, YJ; Winkler, TW; de Las Fuentes, L et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2018.01.015 (2018)
Proteomic determination of the lysine acetylome and phosphoproteome in the rat native inner medullary collecting duct Hyndman, KA; Yang, CR; Jung, HJ; Umejiego, EN; Chou, CL; Knepper, MA; Physiol. Genomics, DOI://10.1152/physiolgenomics.00029.2018 (2018)
Experience-dependent structural plasticity targets dynamic filopodia in regulating dendrite maturation and synaptogenesis Sheng, C; Javed, U; Gibbs, M et al. Nat Commun, DOI://10.1038/s41467-018-05871-5 (2018)
Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa Li, L; Jiao, X; D'Atri, I et al. PLoS Genet., DOI://10.1371/journal.pgen.1007504 (2018)
Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours Ma, X; Liu, Y; Liu, Y et al. Nature, DOI://10.1038/nature25795 (2018)
Argonaute-miRNA Complexes Silence Target mRNAs in the Nucleus of Mammalian Stem Cells Sarshad, AA; Juan, AH; Muler, AIC et al. Mol. Cell, DOI://10.1016/j.molcel.2018.07.020 (2018)
Identification of Retinal Ganglion Cell Firing Patterns Using Clustering Analysis Supplied with Failure Diagnosis Ghahari, A; Kumar, SR; Badea, TC; Int J Neural Syst, DOI://10.1142/S0129065718500089 (2018)

TM6SF2 Promotes Lipidation and Secretion of Hepatitis C Virus in Infected Hepatocytes Boyer, A; Park, SB; de Boer, Y; Li, Q; Liang, TJ; Gastroenterology, DOI://10.1053/j.gastro.2018.08.027 (2018)
A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity Béziat, V; Li, J; Lin, JX et al. Sci Immunol, DOI://10.1126/sciimmunol.aat4956 (2018)
Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease Yao, C; Chen, G; Song, C et al. Nat Commun, DOI://10.1038/s41467-018-05512-x (2018)
Dysregulated neutrophil responses and neutrophil extracellular trap formation and degradation in PAPA syndrome Mistry, P; Carmona-Rivera, C; Ombrello, AK et al. Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2018-213746 (2018)
Distributed cortical structural properties contribute to motor cortical excitability and inhibition Dayan, E; López-Alonso, V; Liew, SL; Cohen, LG; Brain Struct Funct, DOI://10.1007/s00429-018-1722-1 (2018)
Absolute and relative pKa predictions via a DFT approach applied to the SAMPL6 blind challenge Zeng, Q; Jones, MR; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-018-0150-x (2018)

Conformational ensemble of disordered proteins probed by solvent Paramagnetic Relaxation Enhancement (sPRE) Kooshapur, H; Schwieters, C; Tjandra, N; Angew. Chem. Int. Ed. Engl., DOI://10.1002/anie.201807365 (2018)
Predictors of mosaic chromosome Y loss and associations with mortality in the UK Biobank Loftfield, E; Zhou, W; Graubard, BI et al. Sci Rep, DOI://10.1038/s41598-018-30759-1 (2018)
On testing for spatial correspondence between maps of human brain structure and function Alexander-Bloch, AF; Shou, H; Liu, S et al. Neuroimage, DOI://10.1016/j.neuroimage.2018.05.070 (2018)
Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs Matthies, D; Bae, C; Toombes, GE et al. Elife, DOI://10.7554/eLife.37558 (2018)
A DNA methylation biomarker of alcohol consumption Liu, C; Marioni, RE; Hedman, ÅK et al. Mol. Psychiatry, DOI://10.1038/mp.2016.192 (2018)
Targeting the HTLV-I-Regulated BATF3/IRF4 Transcriptional Network in Adult T Cell Leukemia/Lymphoma Nakagawa, M; Shaffer, AL; Ceribelli, M et al. Cancer Cell, DOI://10.1016/j.ccell.2018.06.014 (2018)

Feasibility and accuracy of UF/NCI phantoms and Monte Carlo retrospective dosimetry in children treated on National Wilms Tumor Study protocols Kalapurakal, JA; Gopalakrishnan, M; Mille, M et al. Pediatr Blood Cancer, DOI://10.1002/pbc.27395 (2018)
Structure and energetic basis of overrepresented λ light chain in systemic light chain amyloidosis patients Zhao, J; Zhang, B; Zhu, J; Nussinov, R; Ma, B; Biochim. Biophys. Acta, DOI://10.1016/j.bbadis.2017.12.009 (2018)
A coevolution-guided model for the rotor of the bacterial flagellar motor Khan, S; Guo, TW; Misra, S; Sci Rep, DOI://10.1038/s41598-018-30293-0 (2018)
Allosteric KRas4B Can Modulate SOS1 Fast and Slow Ras Activation Cycles Liao, TJ; Jang, H; Fushman, D; Nussinov, R; Biophys. J., DOI://10.1016/j.bpj.2018.07.016 (2018)
A Muscle-Specific Enhancer RNA Mediates Cohesin Recruitment and Regulates Transcription In trans Tsai, PF; Dell'Orso, S; Rodriguez, J et al. Mol. Cell, DOI://10.1016/j.molcel.2018.06.008 (2018)
Re-analysis of Whole Genome Sequence Data From 279 Ancient Eurasians Reveals Substantial Ancestral Heterogeneity Shriner, D Front Genet, DOI://10.3389/fgene.2018.00268 (2018)

A multiprotein supercomplex controlling oncogenic signalling in lymphoma Phelan, JD; Young, RM; Webster, DE et al. Nature, DOI://10.1038/s41586-018-0290-0 (2018)
Effects of Human Sex Chromosome Dosage on Spatial Chromosome Organization Jowhar, Z; Shachar, S; Gudla, PR et al. Mol. Biol. Cell, DOI://10.1091/mbc.E18-06-0359 (2018)
Glutamatergic Signaling Drives Ketamine-Mediated Response in Depression: Evidence from Dynamic Causal Modeling Gilbert, JR; Yarrington, JS; Wills, KE; Nugent, AC; Zarate, CA; Int. J. Neuropsychopharmacol., DOI://10.1093/ijnp/pyy041 (2018)
Reliably picking the best endpoint Follmann, D Stat Med, DOI://10.1002/sim.7927 (2018)
Association of Coffee Drinking With Mortality by Genetic Variation in Caffeine Metabolism: Findings From the UK Biobank Loftfield, E; Cornelis, MC; Caporaso, N; Yu, K; Sinha, R; Freedman, N; JAMA Intern Med, DOI://10.1001/jamainternmed.2018.2425 (2018)
Cone-rod homeobox CRX controls presynaptic active zone formation in photoreceptors of mammalian retina Assawachananont, J; Kim, SY; Kaya, KD; Fariss, R; Roger, JE; Swaroop, A; Hum. Mol. Genet., DOI://10.1093/hmg/ddy272 (2018)

Prediction of CB[8] host-guest binding free energies in SAMPL6 using the double-decoupling method Han, K; Hudson, PS; Jones, MR; Nishikawa, N; Tofoleanu, F; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-018-0144-8 (2018)
ATAC2GRN: optimized ATAC-seq and DNase1-seq pipelines for rapid and accurate genome regulatory network inference Pranzatelli, TJF; Michael, DG; Chiorini, JA; BMC Genomics, DOI://10.1186/s12864-018-4943-z (2018)
Presynaptic Inhibition Selectively Gates Auditory Transmission to the Brainstem Startle Circuit Tabor, KM; Smith, TS; Brown, M; Bergeron, SA; Briggman, KL; Burgess, HA; Curr. Biol., DOI://10.1016/j.cub.2018.06.020 (2018)
Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse Tubbs, A; Sridharan, S; van Wietmarschen, N et al. Cell, DOI://10.1016/j.cell.2018.07.011 (2018)
Modelling the structure of a ceRNA-theoretical, bipartite microRNA-mRNA interaction network regulating intestinal epithelial cellular pathways using R programming Robinson, JM; Henderson, WA; BMC Res Notes, DOI://10.1186/s13104-018-3126-y (2018)
Cryo-EM of the dynamin polymer assembled on lipid membrane Kong, L; Sochacki, KA; Wang, H et al. Nature, DOI://10.1038/s41586-018-0378-6 (2018)

Decoding microglia responses to psychosocial stress reveals blood-brain barrier breakdown that may drive stress susceptibility Lehmann, ML; Weigel, TK; Cooper, HA; Elkahloun, AG; Kigar, SL; Herkenham, M; Sci Rep, DOI://10.1038/s41598-018-28737-8 (2018)
Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points Heuston, EF; Keller, CA; Lichtenberg, J et al. Epigenetics Chromatin, DOI://10.1186/s13072-018-0195-z (2018)
Dual Roles for Ikaros in Regulation of Macrophage Chromatin State and Inflammatory Gene Expression Oh, KS; Gottschalk, RA; Lounsbury, NW et al. J. Immunol., DOI://10.4049/jimmunol.1800158 (2018)
A Fast Approximate Algorithm for Mapping Long Reads to Large Reference Databases Jain, C; Dilthey, A; Koren, S; Aluru, S; Phillippy, AM; J. Comput. Biol., DOI://10.1089/cmb.2018.0036 (2018)
NLM at ImageCLEF 2018 Visual Question Answering in the Medical Domain Asma Ben Abacha, Soumya Gayen, Jason J Lau, Sivaramakrishnan Rajaraman, and Dina Demner-Fushman ImageCLEF 2018 (2018)
Scalable Biomedical Image Synthesis with GAN Canas, K; Ubiera, B; Liu, X; Liu Y Proceedings of the Practice and Experience on Advanced Research Computing Article No. 95 , doi://10.1145/3219104.3229261 (2018)

The Energetics and Physiological Impact of Cohesin Extrusion Vian, L; Pekowska, A; Rao, SSP et al. Cell, DOI://10.1016/j.cell.2018.03.072 (2018)
Genetic selection of athletic success in sport-hunting dogs Kim, J; Williams, FJ; Dreger, DL et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1800455115 (2018)
Transcriptional signature primes human oral mucosa for rapid wound healing Iglesias-Bartolome, R; Uchiyama, A; Molinolo, AA et al. Sci Transl Med, DOI://10.1126/scitranslmed.aap8798 (2018)
Efficient experimental designs for isotropic generalized diffusion tensor MRI (IGDTI) Avram, AV; Sarlls, JE; Hutchinson, E; Basser, PJ; Magn Reson Med, DOI://10.1002/mrm.26656 (2018)
PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity van Setten, J; Brody, JA; Jamshidi, Y et al. Nat Commun, DOI://10.1038/s41467-018-04766-9 (2018)
Circulating cell-free DNA as a biomarker of tissue injury: Assessment in a cardiac xenotransplantation model Agbor-Enoh, S; Chan, JL; Singh, A et al. J. Heart Lung Transplant., DOI://10.1016/j.healun.2018.04.009 (2018)

Patient iPSC-derived neural stem cells exhibit phenotypes in concordance with the clinical severity of Mucopolysaccharidosis I Swaroop, M; Brooks, MJ; Gieser, L; Swaroop, A; Zheng, W; Hum. Mol. Genet., DOI://10.1093/hmg/ddy259 (2018)
Genetic diversity of noroviruses circulating in a pediatric cohort in Bangladesh Nelson, MI; Mahfuz, M; Chhabra, P et al. J. Infect. Dis., DOI://10.1093/infdis/jiy454 (2018)
Role of gamma-amino-butyric acid in the dorsal anterior cingulate in age-associated changes in cognition Marenco, S; Meyer, C; van der Veen, JW et al. Neuropsychopharmacology, DOI://10.1038/s41386-018-0134-5 (2018)
Reliability of neural activation and connectivity during implicit face emotion processing in youth Haller, SP; Kircanski, K; Stoddard, J et al. Dev Cogn Neurosci, DOI://10.1016/j.dcn.2018.03.010 (2018)
Anionic Phospholipids Bind to and Modulate the Activity of Human TRESK Background K+ Channel Giblin, JP; Etayo, I; Castellanos, A; Andres-Bilbe, A; Gasull, X; Mol. Neurobiol., DOI://10.1007/s12035-018-1244-0 (2018)
Frequency of Loss of Function Variants in LRRK2 in Parkinson Disease Blauwendraat, C; Reed, X; Kia, DA et al. JAMA Neurol, DOI://10.1001/jamaneurol.2018.1885 (2018)

ADAM17-Deficient Mice Model the Transcriptional Signature of Human Atopic Dermatitis Woodring, T; Kobayashi, T; Kim, D; Nagao, K; J. Invest. Dermatol., DOI://10.1016/j.jid.2018.04.021 (2018)
BMX-mediated regulation of multiple tyrosine kinases contributes to castration resistance in prostate cancer Chen, S; Cai, C; Sowalsky, AG et al. Cancer Res., DOI://10.1158/0008-5472.CAN-17-3615 (2018)
7 T MRI reveals hippocampal structural abnormalities associated with memory intrusions in childhood-onset schizophrenia Zhou, D; Liu, S; Zhou, X et al. Schizophr. Res., DOI://10.1016/j.schres.2018.07.023 (2018)
Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits Haljas, K; Amare, AT; Alizadeh, BZ et al. Psychosom Med, DOI://10.1097/PSY.0000000000000555 (2018)
Hepatitis B virus deregulates cell cycle to promote viral replication and a premalignant phenotype Xia, Y; Cheng, X; Li, Y; Valdez, K; Chen, W; Liang, TJ; J. Virol., DOI://10.1128/JVI.00722-18 (2018)
PfCDPK1 is critical for malaria parasite gametogenesis and mosquito infection Bansal, A; Molina-Cruz, A; Brzostowski, J et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1715443115 (2018)

The major depressive disorder GWAS-supported variant rs10514299 in TMEM161B-MEF2C predicts putamen activation during reward processing in alcohol dependence Muench, C; Schwandt, M; Jung, J; Cortes, CR; Momenan, R; Lohoff, FW; Transl Psychiatry, DOI://10.1038/s41398-018-0184-9 (2018)
Whole Blood Gene Expression Associated with Clinical Biological Age Lin, H; Lunetta, KL; Zhao, Q et al. J. Gerontol. A Biol. Sci. Med. Sci., DOI://10.1093/gerona/gly164 (2018)
Ultra-high resolution blood volume fMRI and BOLD fMRI in humans at 9.4 T: Capabilities and challenges Huber, L; Tse, DHY; Wiggins, CJ et al. Neuroimage, DOI://10.1016/j.neuroimage.2018.06.025 (2018)
Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent Smith, CE; Follis, JL; Dashti, HS et al. Mol Nutr Food Res, DOI://10.1002/mnfr.201700347 (2018)
Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas Campbell, JD; Yau, C; Bowlby, R et al. Cell Rep, DOI://10.1016/j.celrep.2018.03.063 (2018)
Structural analysis of influenza vaccine virus-like particles reveals a multicomponent organization McCraw, DM; Gallagher, JR; Torian, U et al. Sci Rep, DOI://10.1038/s41598-018-28700-7 (2018)

Postnatal developmental dynamics of cell type specification genes in Brn3a/Pou4f1 Retinal Ganglion Cells Muzyka, VV; Brooks, M; Badea, TC; Neural Dev, DOI://10.1186/s13064-018-0110-0 (2018)
The Sleep Inbred Panel, a Collection of Inbred Drosophila melanogaster with Extreme Long and Short Sleep Duration Serrano Negron, YL; Hansen, NF; Harbison, ST; G3 (Bethesda), DOI://10.1534/g3.118.200503 (2018)
Deep-learning-assisted Volume Visualization Cheng, HC; Cardone, A; Jain, S et al. IEEE Trans Vis Comput Graph, DOI://10.1109/TVCG.2018.2796085 (2018)
Conformational analysis of replica exchange MD: Temperature-dependent Markov networks for FF amyloid peptides Brajesh Narayan, Colm Herbert, Ye Yuan, Brian J. Rodriguez, Bernard R. Brooks, and Nicolae-Viorel Buchete J. Chem. Phys., 10.1063/1.5027580 (2018)
Recurrent genomic copy alterations deregulate the transcriptome and key signaling networks in head and neck cancer cell lines and tumors with worse prognosis Hui Cheng, Xinping Yang, Han Si, Anthony Saleh, Wenming Xiao, Jamie Coupar, Susanne M. Gollin, Robert L. Ferris, Natalia Issaeva, Wendell G. Yarbrough, Mark E. Prince, Thomas E. Carey, Carter Van Waes and Zhong Chen Cancer Research, 10.1158/1538-7445.AM2018-5346 (2018)
A feasibility study to reduce misclassification error in occupational dose estimates for epidemiological studies using body size-dependent computational phantoms Sarah Kim, Lienard Chang, Elizabeth Mosher, Choonik Lee, and Choonsik IEEE Transactions on Radiation and Plasma Medical Sciences, 0.1109/TRPMS.2018.2847227 (2018)

Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium Merino, J; Dashti, HS; Li, SX et al. Mol. Psychiatry, DOI://10.1038/s41380-018-0079-4 (2018)
Investigation of the seasonal microbiome of Anopheles coluzzii mosquitoes in Mali Krajacich, BJ; Huestis, DL; Dao, A et al. PLoS ONE, DOI://10.1371/journal.pone.0194899 (2018)
Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair Linehan, JL; Harrison, OJ; Han, SJ et al. Cell, DOI://10.1016/j.cell.2017.12.033 (2018)
Visualizing Deep Learning Activations for Improved Malaria Cell Classification Rajaraman S, Antani SK, Jaeger S Proceedings of Machine Learning Research (PMLR), v69, p40-47 (2018)
Comparing deep learning models for population screening using chest radiography Rajaraman S, Antani SK, Candemir S, Xue Z, Abuya J, Kohli M, Alderson P, Thoma GR Proc. SPIE 10575, Medical Imaging 2018: Computer-Aided Diagn (2018)
Strand-specific Dual RNA-seq of Bronchial Epithelial cells Infected with Influenza A/H3N2 Viruses Reveals Splicing of Gene Segment 6 and Novel Host-Virus Interactions Fabozzi, G; Oler, AJ; Liu, P et al. J. Virol., DOI://10.1128/JVI.00518-18 (2018)

Building Blocks of the Outer Membrane: Calculating a general elastic energy model for β-barrel membrane proteins Lessen, HJ; Fleming, PJ; Fleming, KG; Sodt, AJ; J Chem Theory Comput, DOI://10.1021/acs.jctc.8b00377 (2018)
Influence of gut microbiome on mucosal immune activation and SHIV viral transmission in naive macaques Sui, Y; Dzutsev, A; Venzon, D et al. Mucosal Immunol, DOI://10.1038/s41385-018-0029-0 (2018)
Parameterization of the CHARMM All-Atom Force Field for Ether Lipids and Model Linear Ethers Leonard, AN; Pastor, RW; Klauda, JB; J Phys Chem B, DOI://10.1021/acs.jpcb.8b02743 (2018)
MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma Yohe, ME; Gryder, BE; Shern, JF et al. Sci Transl Med, DOI://10.1126/scitranslmed.aan4470 (2018)
The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma Ricketts, CJ; De Cubas, AA; Fan, H et al. Cell Rep, DOI://10.1016/j.celrep.2018.06.032 (2018)
NCR+ ILC3 maintain larger STAT4 reservoir via T-BET to regulate type 1 features upon IL-23 stimulation in mice Mikami, Y; Scarno, G; Zitti, B et al. Eur. J. Immunol., DOI://10.1002/eji.201847480 (2018)
Integrative Bayesian Analysis Identifies Rhabdomyosarcoma Disease Genes Xu, L; Zheng, Y; Liu, J et al. Cell Rep, DOI://10.1016/j.celrep.2018.06.006 (2018)
N-Myc Downstream-Regulated Gene 1 Restricts Hepatitis C Virus Propagation by Regulating Lipid Droplet Biogenesis and Viral Assembly Schweitzer, CJ; Zhang, F; Boyer, A; Valdez, K; Cam, M; Liang, TJ; J. Virol., DOI://10.1128/JVI.01166-17 (2018)
An epigenetic mechanism for cavefish eye degeneration Gore, AV; Tomins, KA; Iben, J et al. Nat Ecol Evol, DOI://10.1038/s41559-018-0569-4 (2018)
Geographic clonal tracking in macaques provides insights into HSPC migration and differentiation Wu, C; Espinoza, DA; Koelle, SJ et al. J. Exp. Med., DOI://10.1084/jem.20171341 (2018)
Defects in the Alternative Splicing-Dependent Regulation of REST Cause Deafness Nakano, Y; Kelly, MC; Rehman, AU et al. Cell, DOI://10.1016/j.cell.2018.06.004 (2018)
Arl2-Mediated Allosteric Release of Farnesylated KRas4B from Shuttling Factor PDEδ Ozdemir, ES; Jang, H; Gursoy, A; Keskin, O; Nussinov, R; J Phys Chem B, DOI://10.1021/acs.jpcb.8b04347 (2018)

Targeting Notch1 and IKKa enhanced NF-κB activation in CD133+ Skin Cancer Stem Cells Quan, XX; Voong Hawk, N; Chen, W et al. Mol. Cancer Ther., DOI://10.1158/1535-7163.MCT-17-0421 (2018)
An Autonomic Network: Synchrony Between Slow Rhythms of Pulse and Brain Resting State Is Associated with Personality and Emotions Shokri-Kojori, E; Tomasi, D; Volkow, ND; Cereb. Cortex, DOI://10.1093/cercor/bhy144 (2018)
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein Kang, Y; Kuybeda, O; de Waal, PW et al. Nature, DOI://10.1038/s41586-018-0215-y (2018)
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries Feitosa, MF; Kraja, AT; Chasman, DI et al. PLoS ONE, DOI://10.1371/journal.pone.0198166 (2018)
Tightly Integrated Genomic and Epigenomic Data Mining Using Tensor Decomposition Fang, J Bioinformatics, DOI://10.1093/bioinformatics/bty513 (2018)
Morphometric analysis and neuroanatomical mapping of the zebrafish brain Gupta, T; Marquart, GD; Horstick, EJ; Tabor, KM; Pajevic, S; Burgess, HA; Methods, DOI://10.1016/j.ymeth.2018.06.008 (2018)

Guide RNA selection for CRISPR-Cas9 transfections in Plasmodium falciparum Ribeiro, JM; Garriga, M; Potchen, N et al. Int. J. Parasitol., DOI://10.1016/j.ijpara.2018.03.009 (2018)
Neoadjuvant-intensive androgen deprivation therapy selects for prostate tumor foci with diverse subclonal oncogenic alterations Sowalsky, AG; Ye, H; Bhasin, M et al. Cancer Res., DOI://10.1158/0008-5472.CAN-18-0610 (2018)
Late manifestation of alloantibody-associated injury and clinical pulmonary antibody-mediated rejection: Evidence from cell-free DNA analysis Agbor-Enoh, S; Jackson, AM; Tunc, I et al. J. Heart Lung Transplant., DOI://10.1016/j.healun.2018.01.1305 (2018)
A subregion-based burden test for simultaneous identification of susceptibility loci and subregions within Zhu, B; Mirabello, L; Chatterjee, N; Genet. Epidemiol., DOI://10.1002/gepi.22134 (2018)
Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma Schmitz, R; Wright, GW; Huang, DW et al. N. Engl. J. Med., DOI://10.1056/NEJMoa1801445 (2018)
HPV integration hijacks and multimerizes a cellular enhancer to generate a viral-cellular super-enhancer that drives high viral oncogene expression Warburton, A; Redmond, CJ; Dooley, KE et al. PLoS Genet., DOI://10.1371/journal.pgen.1007179 (2018)
Publisher Correction: Cryo-EM structure of human rhodopsin bound to an inhibitory G protein Kang, Y; Kuybeda, O; de Waal, PW et al. Nature, DOI://10.1038/s41586-018-0302-0 (2018)
ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming Mishra, P; Tang, W; Putluri, V et al. J. Clin. Invest., DOI://10.1172/JCI93815 (2018)
Innate and adaptive lymphocytes sequentially shape the gut microbiota and lipid metabolism Mao, K; Baptista, AP; Tamoutounour, S et al. Nature, DOI://10.1038/nature25437 (2018)
Normative brain size variation and brain shape diversity in humans Reardon, PK; Seidlitz, J; Vandekar, S et al. Science, DOI://10.1126/science.aar2578 (2018)
Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay Duverger, O; Carlson, JC; Karacz, CM et al. PLoS Genet., DOI://10.1371/journal.pgen.1007168 (2018)
Microbiology catches the cryo-EM bug Earl, LA; Falconieri, V; Subramaniam, S; Curr. Opin. Microbiol., DOI://10.1016/j.mib.2018.02.012 (2018)

Sialome diversity of ticks revealed by RNAseq of single tick salivary glands Perner, J; Kropáčková, S; Kopáček, P; Ribeiro, JMC; PLoS Negl Trop Dis, DOI://10.1371/journal.pntd.0006410 (2018)
RiboSketch: Versatile Visualization of Multi-stranded RNA and DNA Secondary Structure Lu, JS; Bindewald, E; Kasprzak, W; Shapiro, BA; Bioinformatics, DOI://10.1093/bioinformatics/bty468 (2018)
Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density Alonso, N; Estrada, K; Albagha, OME et al. Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2017-212469 (2018)
Structure-Guided Modification of Heterocyclic Antagonists of the P2Y14 Receptor Yu, J; Ciancetta, A; Dudas, S; Duca, S; Lottermoser, J; Jacobson, KA; J. Med. Chem., DOI://10.1021/acs.jmedchem.8b00168 (2018)
A coupled-clock system drives the automaticity of human sinoatrial nodal pacemaker cells Tsutsui, K; Monfredi, OJ; Sirenko-Tagirova, SG et al. Sci Signal, DOI://10.1126/scisignal.aap7608 (2018)
AptaSUITE: A Full-Featured Bioinformatics Framework for the Comprehensive Analysis of Aptamers from HT-SELEX Experiments Hoinka, J; Backofen, R; Przytycka, TM; Mol Ther Nucleic Acids, DOI://10.1016/j.omtn.2018.04.006 (2018)

Modifier locus mapping of a transgenic F2 mouse population identifies CCDC115 as a novel aggressive prostate cancer modifier gene in humans Winter, JM; Curry, NL; Gildea, DM et al. BMC Genomics, DOI://10.1186/s12864-018-4827-2 (2018)
The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma McBride, MJ; Pulice, JL; Beird, HC et al. Cancer Cell, DOI://10.1016/j.ccell.2018.05.002 (2018)
Exploring Substrate Binding in the Extracellular Vestibule of MhsT by Atomistic Simulations and Markov Models Abramyan, AM; Quick, M; Xue, C; Javitch, JA; Shi, L; J Chem Inf Model, DOI://10.1021/acs.jcim.8b00175 (2018)
Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers Hodges, HC; Stanton, BZ; Cermakova, K et al. Nat. Struct. Mol. Biol., DOI://10.1038/s41594-017-0007-3 (2018)
Chromatic: WebAssembly-Based Cancer Genome Viewer Finney, R; Meerzaman, D; Cancer Inform, DOI://10.1177/1176935118771972 (2018)
HiCTMap: Detection and analysis of chromosome territory structure and position by high-throughput imaging Jowhar, Z; Gudla, PR; Shachar, S et al. Methods, DOI://10.1016/j.ymeth.2018.01.013 (2018)

DNA Methylation and Regulatory Elements during Chicken Germline Stem Cell Differentiation He, Y; Zuo, Q; Edwards, J et al. Stem Cell Reports, DOI://10.1016/j.stemcr.2018.03.018 (2018)
Evaluation and comparison of predictive individual-level general surrogates Gabriel, EE; Sachs, MC; Halloran, ME; Biostatistics, DOI://10.1093/biostatistics/kxx037 (2018)
Cracking the DNA Code for V(D)J Recombination Kim, MS; Chuenchor, W; Chen, X et al. Mol. Cell, DOI://10.1016/j.molcel.2018.03.008 (2018)
DLX3-Dependent STAT3 Signaling in Keratinocytes Regulates Skin Immune Homeostasis Bhattacharya, S; Kim, JC; Ogawa, Y et al. J. Invest. Dermatol., DOI://10.1016/j.jid.2017.11.033 (2018)
Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer Zacharakis, N; Chinnasamy, H; Black, M et al. Nat. Med., DOI://10.1038/s41591-018-0040-8 (2018)
Emergence and Evolution of Novel Reassortant Influenza A Viruses in Canines in Southern China Chen, Y; Trovão, NS; Wang, G et al. MBio, DOI://10.1128/mBio.00909-18 (2018)

Rapid Classification and Identification of Multiple Microorganisms with Accurate Statistical Significance via High-Resolution Tandem Mass Spectrometry Alves, G; Wang, G; Ogurtsov, AY et al. J. Am. Soc. Mass Spectrom., DOI://10.1007/s13361-018-1986-y (2018)
Multivalent Display Using Hybrid Virus Nanoparticles Brown, SD Methods Mol. Biol., DOI://10.1007/978-1-4939-7893-9_10 (2018)
Correction: Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations Liang, J; Le, TH; Velez Edwards, DR et al. PLoS Genet., DOI://10.1371/journal.pgen.1007345 (2018)
In-depth investigations of adolescents and adults with holoprosencephaly identify unique characteristics Weiss, K; Kruszka, P; Guillen Sacoto, MJ et al. Genet. Med., DOI://10.1038/gim.2017.68 (2018)
Genome-Wide Mapping of DNA Accessibility and Binding Sites for CREB and C/EBPβ in Vasopressin-Sensitive Collecting Duct Cells Jung, HJ; Raghuram, V; Lee, JW; Knepper, MA; J. Am. Soc. Nephrol., DOI://10.1681/ASN.2017050545 (2018)
Discovering a binary CTCF code with a little help from BORIS Lobanenkov, VV; Zentner, GE; Nucleus, DOI://10.1080/19491034.2017.1394536 (2018)
T-cell responses to TP53 "hotspot" mutations and unique neoantigens expressed by human ovarian cancers Deniger, DC; Pasetto, A; Robbins, PF et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-0573 (2018)
Trait paranoia shapes inter-subject synchrony in brain activity during an ambiguous social narrative Finn, ES; Corlett, PR; Chen, G; Bandettini, PA; Constable, RT; Nat Commun, DOI://10.1038/s41467-018-04387-2 (2018)
Computational Modeling of Mitochondrial Function from a Systems Biology Perspective Cortassa, S; Sollott, SJ; Aon, MA; Methods Mol. Biol., DOI://10.1007/978-1-4939-7831-1_14 (2018)
High burden of birthweight-lowering genetic variants in Africans and Asians Tekola-Ayele, F; Workalemahu, T; Amare, AT; BMC Med, DOI://10.1186/s12916-018-1061-3 (2018)
SWI/SNF and RSC cooperate to reposition and evict promoter nucleosomes at highly expressed genes in yeast Rawal, Y; Chereji, RV; Qiu, H et al. Genes Dev., DOI://10.1101/gad.312850.118 (2018)
Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence Vera-Ramirez, L; Vodnala, SK; Nini, R; Hunter, KW; Green, JE; Nat Commun, DOI://10.1038/s41467-018-04070-6 (2018)

Characterization of Hemagglutinin Antigens on Influenza Virus and within Vaccines Using Electron Microscopy Gallagher, JR; McCraw, DM; Torian, U et al. Vaccines (Basel), DOI://10.3390/vaccines6020031 (2018)
Comparative Population Genomics Analysis of the Mammalian Fungal Pathogen Pneumocystis Cissé, OH; Ma, L; Wei Huang, D et al. MBio, DOI://10.1128/mBio.00381-18 (2018)
Mapping the neuroanatomic substrates of cognition in familial attention deficit hyperactivity disorder Muster, R; Choudhury, S; Sharp, W; Kasparek, S; Sudre, G; Shaw, P; Psychol Med, DOI://10.1017/S0033291718001241 (2018)
Variation in human chromosome 21 ribosomal RNA genes characterized by TAR cloning and long-read sequencing Kim, JH; Dilthey, AT; Nagaraja, R et al. Nucleic Acids Res., DOI://10.1093/nar/gky442 (2018)
Clinically Relevant Cytotoxic Immune Cell Signatures and Clonal Expansion of T-Cell Receptors in High-risk MYCN-not-amplified Human Neuroblastoma Wei, JS; Kuznetsov, IB; Zhang, S et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-0599 (2018)
Functional screening of FGFR4-driven tumorigenesis identifies PI3K/mTOR inhibition as a therapeutic strategy in rhabdomyosarcoma McKinnon, T; Venier, R; Yohe, M et al. Oncogene, DOI://10.1038/s41388-017-0122-y (2018)

The distinct structural preferences of tau protein repeat domains Li, X; Dong, X; Wei, G; Margittai, M; Nussinov, R; Ma, B; Chem. Commun. (Camb.), DOI://10.1039/c8cc01263f (2018)
Atomic Resolution Cryo-EM Structure of β-Galactosidase Bartesaghi, A; Aguerrebere, C; Falconieri, V et al. Structure, DOI://10.1016/j.str.2018.04.004 (2018)
Graph-Theoretic Analysis of Monomethyl Phosphate Clustering in Ionic Solutions Han, K; Venable, RM; Bryant, AM et al. J Phys Chem B, DOI://10.1021/acs.jpcb.7b10730 (2018)
Identification of Novel Targets for Lung Cancer Therapy Using an Induced Pluripotent Stem Cell Model Shukla, V; Rao, M; Zhang, H et al. Ann Am Thorac Soc, DOI://10.1513/AnnalsATS.201707-610MG (2018)
Neutrophil subsets and their gene signature associate with vascular inflammation and coronary atherosclerosis in lupus Carlucci, PM; Purmalek, MM; Dey, AK et al. JCI Insight, DOI://10.1172/jci.insight.99276 (2018)
Molecular dynamics simulations of lipid nanodiscs Pourmousa, M; Pastor, RW; Biochim. Biophys. Acta, DOI://10.1016/j.bbamem.2018.04.015 (2018)

Epigenome-Wide Association Study of Soluble Tumor Necrosis Factor Receptor 2 Levels in the Framingham Heart Study Mendelson, MM; Johannes, R; Liu, C et al. Front Pharmacol, DOI://10.3389/fphar.2018.00207 (2018)
Experimental and Computational Protocols for Studies of Cross-Seeding Amyloid Assemblies Ren, B; Hu, R; Zhang, M et al. Methods Mol. Biol., DOI://10.1007/978-1-4939-7811-3_27 (2018)
Replica Exchange Molecular Dynamics: A Practical Application Protocol with Solutions to Common Problems and a Peptide Aggregation and Self-Assembly Example Qi, R; Wei, G; Ma, B; Nussinov, R; Methods Mol. Biol., DOI://10.1007/978-1-4939-7811-3_5 (2018)
Dynamic Behavior of RNA Nanoparticles Analyzed by AFM on a Mica/Air Interface Sajja, S; Chandler, M; Fedorov, D et al. Langmuir, DOI://10.1021/acs.langmuir.8b00105 (2018)
Iron homeostasis regulates facultative heterochromatin assembly in adaptive genome control Gallagher, PS; Larkin, M; Thillainadesan, G et al. Nat. Struct. Mol. Biol., DOI://10.1038/s41594-018-0056-2 (2018)
Germline gain-of-function myeloid differentiation primary response gene-88 (MYD88) mutation in a child with severe arthritis Sikora, KA; Bennett, JR; Vyncke, L et al. J. Allergy Clin. Immunol., DOI://10.1016/j.jaci.2018.01.027 (2018)

iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications Ou, J; Ball, JM; Luan, Y et al. Cell, DOI://10.1016/j.cell.2018.03.010 (2018)
Whole-Exome Sequencing to Identify Rare Variants and Gene Networks That Increase Susceptibility to Scleroderma in African Americans Gourh, P; Remmers, EF; Boyden, SE et al. , DOI://10.1002/art.40541 (2018)
Irritability Trajectories, Cortical Thickness, and Clinical Outcomes in a Sample Enriched for Preschool Depression Pagliaccio, D; Pine, DS; Barch, DM; Luby, JL; Leibenluft, E; J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2018.02.010 (2018)
Temporal Variability of Oral Microbiota over 10 Months and the Implications for Future Epidemiologic Studies Vogtmann, E; Hua, X; Zhou, L et al. Cancer Epidemiol. Biomarkers Prev., DOI://10.1158/1055-9965.EPI-17-1004 (2018)
Day length is associated with physical activity and sedentary behavior among older women Schepps, MA; Shiroma, EJ; Kamada, M; Harris, TB; Lee, IM; Sci Rep, DOI://10.1038/s41598-018-25145-w (2018)
Position-specific intron retention is mediated by the histone methyltransferase SDG725 Wei, G; Liu, K; Shen, T et al. BMC Biol., DOI://10.1186/s12915-018-0513-8 (2018)

A draft genome sequence for the Ixodes scapularis cell line, ISE6 Miller, JR; Koren, S; Dilley, KA et al. F1000Res, DOI://10.12688/f1000research.13635.1 (2018)
Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group Hibar, DP; Westlye, LT; Doan, NT et al. Mol. Psychiatry, DOI://10.1038/mp.2017.73 (2018)
Insulin promoter in human pancreatic β cells contacts diabetes susceptibility loci and regulates genes affecting insulin metabolism Jian, X; Felsenfeld, G; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1803146115 (2018)
Organization of the core respiratory network: Insights from optogenetic and modeling studies Ausborn, J; Koizumi, H; Barnett, WH et al. PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1006148 (2018)
Dealing with competing risks in clinical trials: How to choose the primary efficacy analysis Troendle, JF; Leifer, ES; Kunz, L; Stat Med, DOI://10.1002/sim.7800 (2018)
A cleavage product of Polycystin-1 is a mitochondrial matrix protein that affects mitochondria morphology and function when heterologously expressed Lin, CC; Kurashige, M; Liu, Y et al. Sci Rep, DOI://10.1038/s41598-018-20856-6 (2018)

Insufficient evidence for pathogenicity of SNCA His50Gln (H50Q) in Parkinson's disease Blauwendraat, C; Kia, DA; Pihlstrøm, L et al. Neurobiol. Aging, DOI://10.1016/j.neurobiolaging.2017.12.012 (2018)
A multicohort, longitudinal study of cerebellar development in attention deficit hyperactivity disorder Shaw, P; Ishii-Takahashi, A; Park, MT et al. J Child Psychol Psychiatry, DOI://10.1111/jcpp.12920 (2018)
Morphometric Similarity Networks Detect Microscale Cortical Organization and Predict Inter-Individual Cognitive Variation Seidlitz, J; Váša, F; Shinn, M et al. Neuron, DOI://10.1016/j.neuron.2017.11.039 (2018)
Feedforward Inhibition Allows Input Summation to Vary in Recurrent Cortical Networks Histed, MH eNeuro, DOI://10.1523/ENEURO.0356-17.2018 (2018)
Homeobox transcription factor DLX4 is not necessary for skin development and homeostasis Bhattacharya, S; Duverger, O; Brooks, SR; Morasso, MI; Exp. Dermatol., DOI://10.1111/exd.13503 (2018)
Single-tubule RNA-Seq uncovers signaling mechanisms that defend against hyponatremia in SIADH Lee, JW; Alsady, M; Chou, CL et al. Kidney Int., DOI://10.1016/j.kint.2017.06.008 (2018)

SIRT1 is a transcriptional enhancer of the glucocorticoid receptor acting independently to its deacetylase activity Suzuki, S; Iben, JR; Coon, SL; Kino, T; Mol. Cell. Endocrinol., DOI://10.1016/j.mce.2017.09.012 (2018)
Outcomes of Children and Adolescents with Advanced Hereditary Medullary Thyroid Carcinoma Treated with Vandetanib Kraft, IL; Akshintala, S; Zhu, Y et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-17-2101 (2018)
A mutational comparison of adult and adolescent and young adult (AYA) colon cancer Tricoli, JV; Boardman, LA; Patidar, R et al. Cancer, DOI://10.1002/cncr.31136 (2018)
Comprehensive Synthesis of Amino Acid-Derived Thiazole Peptidomimetic Analogues to Understand the Enigmatic Drug/Substrate-Binding Site of P-Glycoprotein Patel, BA; Abel, B; Barbuti, AM et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.7b01340 (2018)
Massively Parallel Single Nucleus Transcriptional Profiling Defines Spinal Cord Neurons and Their Activity during Behavior Sathyamurthy, A; Johnson, KR; Matson, KJE et al. Cell Rep, DOI://10.1016/j.celrep.2018.02.003 (2018)
Effects on gene expression and behavior of untagged short tandem repeats: the case of arginine vasopressin receptor 1a (AVPR1a) and externalizing behaviors Landefeld, CC; Hodgkinson, CA; Spagnolo, PA et al. Transl Psychiatry, DOI://10.1038/s41398-018-0120-z (2018)

Interrogating the Functions of PRDM9 Domains in Meiosis Thibault-Sennett, S; Yu, Q; Smagulova, F et al. Genetics, DOI://10.1534/genetics.118.300565 (2018)
Using standard microbiome reference groups to simplify beta-diversity analyses and facilitate independent validation Maziarz, M; Pfeiffer, RM; Wan, Y; Gail, MH; Bioinformatics, DOI://10.1093/bioinformatics/bty297 (2018)
Electrophysiological heterogeneity of pacemaker cells in the rabbit intercaval region, including the SA node: insights from recording multiple ion currents in each cell Monfredi, O; Tsutsui, K; Ziman, B; Stern, MD; Lakatta, EG; Maltsev, VA; Am. J. Physiol. Heart Circ. Physiol., DOI://10.1152/ajpheart.00253.2016 (2018)
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay Baird, TD; Cheng, KC; Chen, YC et al. Elife, DOI://10.7554/eLife.33178 (2018)
Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors Giannelou, A; Wang, H; Zhou, Q et al. Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2017-212401 (2018)
A joint spatial factor analysis model to accommodate data from misaligned areal units with application to Louisiana social vulnerability Nethery, RC; Sandler, DP; Zhao, S; Engel, LS; Kwok, RK; Biostatistics, DOI://10.1093/biostatistics/kxy016 (2018)

Somatic activating mutations in MAP2K1 cause melorheostosis Kang, H; Jha, S; Deng, Z et al. Nat Commun, DOI://10.1038/s41467-018-03720-z (2018)
Characterization of clinically used oral antiseptics as quadruplex-binding ligands Calabrese, DR; Zlotkowski, K; Alden, S et al. Nucleic Acids Res., DOI://10.1093/nar/gky084 (2018)
Analysis of the 9p21.3 sequence associated with coronary artery disease reveals a tendency for duplication in a CAD patient Kouprina, N; Liskovykh, M; Lee, NCO et al. Oncotarget, DOI://10.18632/oncotarget.24567 (2018)
A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope Zhou, T; Zheng, A; Baxa, U et al. Immunity, DOI://10.1016/j.immuni.2018.02.013 (2018)
Statistical power comparisons at 3T and 7T with a GO / NOGO task Torrisi, S; Chen, G; Glen, D et al. Neuroimage, DOI://10.1016/j.neuroimage.2018.03.071 (2018)
Gcn4 Binding in Coding Regions Can Activate Internal and Canonical 5' Promoters in Yeast Rawal, Y; Chereji, RV; Valabhoju, V et al. Mol. Cell, DOI://10.1016/j.molcel.2018.03.007 (2018)

Deep sequencing of the mitochondrial genome reveals common heteroplasmic sites in NADH dehydrogenase genes Liu, C; Fetterman, JL; Liu, P et al. Hum. Genet., DOI://10.1007/s00439-018-1873-4 (2018)
A Latent Variable Approach to Differentiating Neural Mechanisms of Irritability and Anxiety in Youth Kircanski, K; White, LK; Tseng, WL et al. JAMA Psychiatry, DOI://10.1001/jamapsychiatry.2018.0468 (2018)
The impact of aging on primate hematopoiesis as interrogated by clonal tracking Yu, KR; Espinoza, DA; Wu, C et al. Blood, DOI://10.1182/blood-2017-08-802033 (2018)
A method for determining haploid and triploid genotypes and their association with vascular phenotypes in Williams syndrome and 7q11.23 duplication syndrome Gregory, MD; Kolachana, B; Yao, Y et al. BMC Med. Genet., DOI://10.1186/s12881-018-0563-3 (2018)
A Novel Method to Extend a Partial-Body CT for the Reconstruction of Dose to Organs beyond the Scan Range Kuzmin, GA; Mille, MM; Jung, JW et al. Radiat. Res., DOI://10.1667/RR14999.1 (2018)
Association of Methylation Signals With Incident Coronary Heart Disease in an Epigenome-Wide Assessment of Circulating Tumor Necrosis Factor α Aslibekyan, S; Agha, G; Colicino, E et al. JAMA Cardiol, DOI://10.1001/jamacardio.2018.0510 (2018)

Inferring properties of disordered chains from FRET transfer efficiencies Zheng, W; Zerze, GH; Borgia, A; Mittal, J; Schuler, B; Best, RB; J Chem Phys, DOI://10.1063/1.5006954 (2018)
Genome-wide Analyses Identify KIF5A as a Novel ALS Gene Nicolas, A; Kenna, KP; Renton, AE et al. Neuron, DOI://10.1016/j.neuron.2018.02.027 (2018)
Quantification of Human Microbiome Stability Over Six Months: Implications for Epidemiologic Studies Sinha, R; Goedert, JJ; Vogtmann, E et al. Am. J. Epidemiol., DOI://10.1093/aje/kwy064 (2018)
IL1RN Variation Influences both Disease Susceptibility and Response to Human Recombinant IL-1RA Therapy in Systemic Juvenile Idiopathic Arthritis Arthur, VL; Shuldiner, E; Remmers, EF et al. , DOI://10.1002/art.40498 (2018)
Emollient use alters skin barrier and microbes in infants at risk for developing atopic dermatitis Glatz, M; Jo, JH; Kennedy, EA et al. PLoS ONE, DOI://10.1371/journal.pone.0192443 (2018)
A trapped human PPM1A-phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity Debnath, S; Kosek, D; Tagad, HD et al. J. Biol. Chem., DOI://10.1074/jbc.RA117.001213 (2018)

Default Mode Connectivity in Major Depressive Disorder Measured Up to 10 Days After Ketamine Administration Evans, JW; Szczepanik, J; Brutsché, N; Park, LT; Nugent, AC; Zarate, CA; Biol. Psychiatry, DOI://10.1016/j.biopsych.2018.01.027 (2018)
An Extended Guinier Analysis for Intrinsically Disordered Proteins Zheng, W; Best, RB; J. Mol. Biol., DOI://10.1016/j.jmb.2018.03.007 (2018)
ZFR coordinates crosstalk between RNA decay and transcription in innate immunity Haque, N; Ouda, R; Chen, C; Ozato, K; Hogg, JR; Nat Commun, DOI://10.1038/s41467-018-03326-5 (2018)
Lifestyle, metabolite, and genetic determinants of formate concentrations in a cross-sectional study in young, healthy adults Brosnan, JT; Mills, JL; Ueland, PM et al. Am. J. Clin. Nutr., DOI://10.1093/ajcn/nqx065 (2018)
Shep regulates Drosophila neuronal remodeling by controlling transcription of its chromatin targets Chen, D; Dale, RK; Lei, EP; Development, DOI://10.1242/dev.154047 (2018)
Balancing Force Field Protein-Lipid Interactions To Capture Transmembrane Helix-Helix Association Domanski, J; Sansom, MSP; Stansfeld, PJ; Best, RB; J Chem Theory Comput, DOI://10.1021/acs.jctc.7b00983 (2018)
Targeting loss of the Hippo signaling pathway in NF2-deficient papillary kidney cancers Sourbier, C; Liao, PJ; Ricketts, CJ et al. Oncotarget, DOI://10.18632/oncotarget.24112 (2018)
Metabolic profiles of triple-negative and luminal A breast cancer subtypes in African-American identify key metabolic differences Tayyari, F; Gowda, GAN; Olopade, OF et al. Oncotarget, DOI://10.18632/oncotarget.24433 (2018)
Gestational cytokine concentrations and neurocognitive development at 7 years Ghassabian, A; Albert, PS; Hornig, M et al. Transl Psychiatry, DOI://10.1038/s41398-018-0112-z (2018)
LMTK3 confers chemo-resistance in breast cancer Stebbing, J; Shah, K; Lit, LC et al. Oncogene, DOI://10.1038/s41388-018-0197-0 (2018)
A deep insight into the male and female sialotranscriptome of adult Culex tarsalis mosquitoes Ribeiro, JMC; Martin-Martin, I; Moreira, FR; Bernard, KA; Calvo, E; Insect Biochem. Mol. Biol., DOI://10.1016/j.ibmb.2018.03.001 (2018)
Argonaute2 and LaminB modulate gene expression by controlling chromatin topology Nazer, E; Dale, RK; Chinen, M; Radmanesh, B; Lei, EP; PLoS Genet., DOI://10.1371/journal.pgen.1007276 (2018)

In Vitro Modeling of Human Germ Cell Development Using Pluripotent Stem Cells Zhao, Y; Ye, S; Liang, D et al. Stem Cell Reports, DOI://10.1016/j.stemcr.2018.01.001 (2018)
Evidence of subgroups in smokers as revealed in clinical measures and evaluated by neuroimaging data: a preliminary study Ding, X; Salmeron, BJ; Wang, J; Yang, Y; Stein, EA; Ross, TJ; Addict Biol, DOI://10.1111/adb.12620 (2018)
Mechanism of Darunavir (DRV)'s High Genetic Barrier to HIV-1 Resistance: A Key V32I Substitution in Protease Rarely Occurs, but Once It Occurs, It Predisposes HIV-1 To Develop DRV Resistance Aoki, M; Das, D; Hayashi, H et al. MBio, DOI://10.1128/mBio.02425-17 (2018)
Co-evolutionary fitness landscapes for sequence design Tian, P; Louis, JM; Baber, JL; Aniana, A; Best, R; Angew. Chem. Int. Ed. Engl., DOI://10.1002/anie.201713220 (2018)
An Efficient Single-Cell RNA-Seq Approach to Identify Neoantigen-Specific T Cell Receptors Lu, YC; Zheng, Z; Robbins, PF et al. Mol. Ther., DOI://10.1016/j.ymthe.2017.10.018 (2018)
Nanopore sequencing and assembly of a human genome with ultra-long reads Jain, M; Koren, S; Miga, KH et al. Nat. Biotechnol., DOI://10.1038/nbt.4060 (2018)

Impact of time-of-day on diffusivity measures of brain tissue derived from diffusion tensor imaging Thomas, C; Sadeghi, N; Nayak, A et al. Neuroimage, DOI://10.1016/j.neuroimage.2018.02.026 (2018)
Verdazyl-ribose: A new radical for solid-state dynamic nuclear polarization at high magnetic field Thurber, KR; Le, TN; Changcoco, V; Brook, DJR; J. Magn. Reson., DOI://10.1016/j.jmr.2018.02.016 (2018)
An insight into the salivary gland and fat body transcriptome of Panstrongylus lignarius (Hemiptera: Heteroptera), the main vector of Chagas disease in Peru Nevoa, JC; Mendes, MT; da Silva, MV; Soares, SC; Oliveira, CJF; Ribeiro, JMC; PLoS Negl Trop Dis, DOI://10.1371/journal.pntd.0006243 (2018)
Minoxidil improves vascular compliance, restores cerebral blood flow and alters extracellular matrix gene expression in a model of chronic vascular stiffness Knutsen, R; Beeman, SC; Broekelmann, TJ et al. Am. J. Physiol. Heart Circ. Physiol., DOI://10.1152/ajpheart.00683.2017 (2018)
Highly Disordered Amyloid-β Monomer Probed by Single-Molecule FRET and MD Simulation Meng, F; Bellaiche, MMJ; Kim, JY; Zerze, GH; Best, RB; Chung, HS; Biophys. J., DOI://10.1016/j.bpj.2017.12.025 (2018)
Ketamine has distinct electrophysiological and behavioral effects in depressed and healthy subjects Nugent, AC; Ballard, ED; Gould, TD et al. Mol. Psychiatry, DOI://10.1038/s41380-018-0028-2 (2018)

Identification of Casz1 as a Regulatory Protein Controlling T Helper Cell Differentiation, Inflammation, and Immunity Bhaskaran, N; Liu, Z; Saravanamuthu, SS et al. Front Immunol, DOI://10.3389/fimmu.2018.00184 (2018)
GRL-079, a Novel HIV-1 Protease Inhibitor, Is Extremely Potent against Multidrug-Resistant HIV-1 Variants and Has a High Genetic Barrier against the Emergence of Resistant Variants Delino NS, Aoki M, Hayashi H, Hattori SI, Chang SB, Takamatsu Y, Martyr CD, Das D, Ghosh AK, Mitsuya H Antimicrob Agents Chemother. , doi: 10.1128/AAC.02060-17 (2018)
Design and statistical considerations for studies evaluating the efficacy of a single dose of the human papillomavirus (HPV) vaccine Sampson, JN; Hildesheim, A; Herrero, R; Gonzalez, P; Kreimer, A; Gail, MH; Contemp Clin Trials, DOI://10.1016/j.cct.2018.02.010 (2018)
Estimating recurrence and incidence of preterm birth subject to measurement error in gestational age: A hidden Markov modeling approach Albert, PS Stat Med, DOI://10.1002/sim.7624 (2018)
Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas Cobo, I; Martinelli, P; Flández, M et al. Nature, DOI://10.1038/nature25751 (2018)
Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells Hu, G; Cui, K; Fang, D et al. Immunity, DOI://10.1016/j.immuni.2018.01.013 (2018)

Extreme disorder in an ultrahigh-affinity protein complex Borgia, A; Borgia, MB; Bugge, K et al. Nature, DOI://10.1038/nature25762 (2018)
Assessment of PCXMC for patients with different body size in chest and abdominal x ray examinations: a Monte Carlo simulation study Borrego, D; Lowe, EM; Kitahara, CM; Lee, C; Phys Med Biol, DOI://10.1088/1361-6560/aab13e (2018)
Epigenome comparisons reveal linkage between gene expression and postnatal remodeling of chromatin domain topology Howard, BH; Hirai, TH; Russanova, VR; PLoS ONE, DOI://10.1371/journal.pone.0191033 (2018)
Dose coefficients for children and young adolescents exposed to external neutron fields Griffin, KT; Mille, M; Lee, C; J Radiol Prot, DOI://10.1088/1361-6498/aab126 (2018)
Structural Modulation of Human Amylin Protofilaments by Naturally Occurring Mutations Tofoleanu, F; Yuan, Y; Pickard, FC; Tywoniuk, B; Brooks, BR; Buchete, NV; J Phys Chem B, DOI://10.1021/acs.jpcb.7b12083 (2018)
CD63, MHC class 1, and CD47 identify subsets of extracellular vesicles containing distinct populations of noncoding RNAs Kaur, S; Elkahloun, AG; Arakelyan, A et al. Sci Rep, DOI://10.1038/s41598-018-20936-7 (2018)

Ridding fMRI data of motion-related influences: Removal of signals with distinct spatial and physical bases in multiecho data Power, JD; Plitt, M; Gotts, SJ et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1720985115 (2018)
The Antimicrobial Peptide CRAMP Is Essential for Colon Homeostasis by Maintaining Microbiota Balance Yoshimura, T; McLean, MH; Dzutsev, AK et al. J. Immunol., DOI://10.4049/jimmunol.1602073 (2018)
Transient Receptor Potential Channels TRPM4 and TRPC3 Critically Contribute to Respiratory Motor Pattern Formation but not Rhythmogenesis in Rodent Brainstem Circuits Koizumi, H; John, TT; Chia, JX et al. eNeuro, DOI://10.1523/ENEURO.0332-17.2018 (2018)
Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of Bacterial Plasmids Conferring Carbapenem Resistance Weingarten, RA; Johnson, RC; Conlan, S et al. MBio, DOI://10.1128/mBio.02011-17 (2018)
Raf-1 Cysteine-Rich Domain Increases the Affinity of K-Ras/Raf at the Membrane, Promoting MAPK Signaling Li, S; Jang, H; Zhang, J; Nussinov, R; Structure, DOI://10.1016/j.str.2018.01.011 (2018)
5-Azacytidine prevents relapse and produces long-term complete remissions in leukemia xenografts treated with Moxetumomab pasudotox Müller, F; Cunningham, T; Stookey, S et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1714512115 (2018)

Global changes of H3K27me3 domains and Polycomb group protein distribution in the absence of recruiters Spps or Pho Brown, JL; Sun, MA; Kassis, JA; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1716299115 (2018)
Precise genome-wide mapping of single nucleosomes and linkers in vivo Chereji, RV; Ramachandran, S; Bryson, TD; Henikoff, S; Genome Biol., DOI://10.1186/s13059-018-1398-0 (2018)
The klotho-related protein KLPH (lctl) has preferred expression in lens and is essential for expression of clic5 and normal lens suture formation Fan, J; Lerner, J; Wyatt, MK et al. Exp. Eye Res., DOI://10.1016/j.exer.2018.02.001 (2018)
Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer Klein, AP; Wolpin, BM; Risch, HA et al. Nat Commun, DOI://10.1038/s41467-018-02942-5 (2018)
Self-reported executive function and hoarding in adults with obsessive-compulsive disorder Samuels, J; Bienvenu, OJ; Krasnow, J et al. Compr Psychiatry, DOI://10.1016/j.comppsych.2017.11.009 (2018)
Sequence determinants of protein phase behavior from a coarse-grained model Dignon, GL; Zheng, W; Kim, YC; Best, RB; Mittal, J; PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1005941 (2018)

Genomic Heterogeneity Within Individual Prostate Cancer Foci Impacts Predictive Biomarkers of Targeted Therapy VanderWeele, DJ; Finney, R; Katayama, K et al. Eur Urol Focus, DOI://10.1016/j.euf.2018.01.006 (2018)
Extended amygdala connectivity changes during sustained shock anticipation Torrisi, S; Gorka, AX; Gonzalez-Castillo, J et al. Transl Psychiatry, DOI://10.1038/s41398-017-0074-6 (2018)
Estimation Approaches of Sufficient Reduction under Kronecker Product Structure Wei Wang Master's Thesis, George Washington University, Washington DC (2018)
Unraveling the molecular mechanism of interactions of the Rho GTPases Cdc42 and Rac1 with the scaffolding protein IQGAP2 Ozdemir, ES; Jang, H; Gursoy, A et al. J. Biol. Chem., DOI://10.1074/jbc.RA117.001596 (2018)
Binding kinetics of ultrasmall gold nanoparticles with proteins André Lira, Rodrigo Ferreira, Ricardo Torquato, Huaying Zhao, Maria Luiza Oliva, Sergio A. Hassan, Peter Schuck and Alioscka A Sousa Nanoscale, DOI: 10.1039/C7NR06810G (2018)
SpotLearn: Convolutional Neural Network for Detection of Fluorescence In Situ Hybridization (FISH) Signals in High-Throughput Imaging Approaches Prabhakar Gudla, Koh Nakayama, Gianluca Pegoraro, Tom Misteli Cold Spring Harb Symp Quant Biol, 10.1101/sqb.2017.82.033761 (2018)

Cleavage of TL1A Differentially Regulates Its Effects on Innate and Adaptive Immune Cells Ferdinand, JR; Richard, AC; Meylan, F; Al-Shamkhani, A; Siegel, RM; J. Immunol., DOI://10.4049/jimmunol.1700891 (2018)
De novo assembly of the complex genome of Nippostrongylus brasiliensis using MinION long reads Eccles, D; Chandler, J; Camberis, M et al. BMC Biol., DOI://10.1186/s12915-017-0473-4 (2018)
Accelerometer-Measured Physical Activity and Sedentary Behavior in Relation to All-Cause Mortality: The Women's Health Study Lee, IM; Shiroma, EJ; Evenson, KR; Kamada, M; LaCroix, AZ; Buring, JE; Circulation, DOI://10.1161/CIRCULATIONAHA.117.031300 (2018)
Altered avalanche dynamics in a developmental NMDAR hypofunction model of cognitive impairment Seshadri, S; Klaus, A; Winkowski, DE; Kanold, PO; Plenz, D; Transl Psychiatry, DOI://10.1038/s41398-017-0060-z (2018)
Single-cell analysis reveals cancer stem cell heterogeneity in hepatocellular carcinoma Zheng, H; Pomyen, Y; Hernandez, MO et al. Hepatology, DOI://10.1002/hep.29778 (2018)
Prediction of nearest neighbor effects on backbone torsion angles and NMR scalar coupling constants in disordered proteins Shen, Y; Roche, J; Grishaev, A; Bax, A; Protein Sci., DOI://10.1002/pro.3292 (2018)

2017 (401 papers)

Effects of spatial fMRI resolution on the classification of naturalistic movies Mandelkow, H; de Zwart, JA; Duyn, JH; Neuroimage, DOI://10.1016/j.neuroimage.2017.08.053 (2017)
Lipid and Peptide Diffusion in Bilayers: The Saffman-Delbrück Model and Periodic Boundary Conditions Venable R; Ingolfsson H; Lerner MG et al J. Phys. Chem. B, DOI: 10.1021/acs.jpcb.6b09111 (2017)
Extracellular vesicles, exosomes and shedding vesicles in regenerative medicine - a new paradigm for tissue repair Bjørge, IM; Kim, SY; Mano, JF; Kalionis, B; Chrzanowski, W; Biomater Sci, DOI://10.1039/c7bm00479f (2017)
Automatic magnetic resonance prostate segmentation by deep learning with holistically nested networks Cheng, R; Roth, HR; Lay, N et al. J Med Imaging (Bellingham), DOI://10.1117/1.JMI.4.4.041302 (2017)
The emerging importance and challenges of the human mycobiome Kong, HH; Morris, A; Virulence, DOI://10.1080/21505594.2017.1279780 (2017)
Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells Lin, JX; Du, N; Li, P et al. Nat Commun, DOI://10.1038/s41467-017-01477-5 (2017)

BRD4 facilitates DNA damage response and represses CBX5/Heterochromatin protein 1 (HP1) Pongas, G; Kim, MK; Min, DJ et al. Oncotarget, DOI://10.18632/oncotarget.17572 (2017)
Bitopic fluorescent antagonists of the A2A adenosine receptor based on pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine functionalized congeners Duroux, R; Ciancetta, A; Mannes, P et al. Medchemcomm, DOI://10.1039/C7MD00247E (2017)
Haploinsufficiency of ZNF462 is associated with craniofacial anomalies, corpus callosum dysgenesis, ptosis, and developmental delay Weiss, K; Wigby, K; Fannemel, M et al. Eur. J. Hum. Genet., DOI://10.1038/ejhg.2017.86 (2017)
Longitudinal Structural and Functional Differences Between Proportional and Poor Motor Recovery After Stroke Guggisberg, AG; Nicolo, P; Cohen, LG; Schnider, A; Buch, ER; Neurorehabil Neural Repair, DOI://10.1177/1545968317740634 (2017)
STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes: Functional dissection of the Il2ra gene locus Li, P; Mitra, S; Spolski, R et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1714019114 (2017)
Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis van Rooij, FJA; Qayyum, R; Smith, AV et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2016.11.016 (2017)

Testis-specific transcriptional regulators selectively occupy BORIS-bound CTCF target regions in mouse male germ cells Rivero-Hinojosa, S; Kang, S; Lobanenkov, VV; Zentner, GE; Sci Rep, DOI://10.1038/srep41279 (2017)
Common Molecular Subtypes Among Asian Hepatocellular Carcinoma and Cholangiocarcinoma Chaisaingmongkol, J; Budhu, A; Dang, H et al. Cancer Cell, DOI://10.1016/j.ccell.2017.05.009 (2017)
Visualizing abnormalities in chest radiographs through salient network activations in Deep Learning Rajaraman S, Antani SK, Xue Z, Candemir S, Jaeger S, Thoma GR Proc. IEEE Life Sciences Conference (LSC), Sydney, Australia, 10.1109/LSC.2017.826814 (2017)
PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability Gryder, BE; Yohe, ME; Chou, HC et al. Cancer Discov, DOI://10.1158/2159-8290.CD-16-1297 (2017)
Parental bonding and hoarding in obsessive-compulsive disorder Chen, D; Bienvenu, OJ; Krasnow, J et al. Compr Psychiatry, DOI://10.1016/j.comppsych.2016.11.004 (2017)
Systems-level identification of PKA-dependent signaling in epithelial cells Isobe, K; Jung, HJ; Yang, CR et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1709123114 (2017)
Characterization of an Immunogenic Mutation in a Patient with Metastatic Triple-Negative Breast Cancer Assadipour, Y; Zacharakis, N; Crystal, JS et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-16-1423 (2017)
Association of red cell distribution width with all-cause and cardiovascular-specific mortality in African American and white adults: a prospective cohort study Tajuddin, SM; Nalls, MA; Zonderman, AB; Evans, MK; J Transl Med, DOI://10.1186/s12967-017-1313-6 (2017)
Sieve analysis using the number of infecting pathogens Follmann, D; Huang, CY; Biometrics, DOI://10.1111/biom.12833 (2017)
Meat Consumption During Pregnancy and Substance Misuse Among Adolescent Offspring: Stratification of TCN2 Genetic Variants Hibbeln, JR; SanGiovanni, JP; Golding, J et al. Alcohol. Clin. Exp. Res., DOI://10.1111/acer.13494 (2017)
Applying rigor and reproducibility standards to assay donor-derived cell-free DNA as a non-invasive method for detection of acute rejection and graft injury after heart transplantation Agbor-Enoh, S; Tunc, I; De Vlaminck, I et al. J. Heart Lung Transplant., DOI://10.1016/j.healun.2017.05.026 (2017)
A Systems Biology Approach to Investigating Sex Differences in Cardiac Hypertrophy Harrington, J; Fillmore, N; Gao, S et al. J Am Heart Assoc, DOI://10.1161/JAHA.117.005838 (2017)

Broadly protective murine monoclonal antibodies against influenza B virus target highly conserved neuraminidase epitopes Wohlbold, TJ; Podolsky, KA; Chromikova, V et al. Nat Microbiol, DOI://10.1038/s41564-017-0011-8 (2017)
Genome-wide association meta-analysis of fish and EPA+DHA consumption in 17 US and European cohorts Mozaffarian, D; Dashti, HS; Wojczynski, MK et al. PLoS ONE, DOI://10.1371/journal.pone.0186456 (2017)
Amygdala Contributions to Stimulus-Reward Encoding in the Macaque Medial and Orbital Frontal Cortex during Learning Rudebeck, PH; Ripple, JA; Mitz, AR; Averbeck, BB; Murray, EA; J. Neurosci., DOI://10.1523/JNEUROSCI.0933-16.2017 (2017)
Genome-wide identification of histone H2A and histone variant H2A.Z-interacting proteins by bPPI-seq Zhang, Y; Ku, WL; Liu, S et al. Cell Res., DOI://10.1038/cr.2017.112 (2017)
Deciphering the olfactory repertoire of the tiger mosquito Aedes albopictus Lombardo, F; Salvemini, M; Fiorillo, C et al. BMC Genomics, DOI://10.1186/s12864-017-4144-1 (2017)
Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS Taskesen, E; Mishra, A; van der Sluis, S et al. Sci Rep, DOI://10.1038/s41598-017-09320-z (2017)

Shelterin components mediate genome reorganization in response to replication stress Mizuguchi, T; Taneja, N; Matsuda, E et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1705527114 (2017)
The Interplay between Long- and Short-Range Temporal Correlations Shapes Cortex Dynamics across Vigilance States Meisel, C; Klaus, A; Vyazovskiy, VV; Plenz, D; J. Neurosci., DOI://10.1523/JNEUROSCI.0448-17.2017 (2017)
Insights Into Onchocerca volvulus Population Biology Through Multilocus Immunophenotyping Norice-Tra, CT; Ribeiro, J; Bennuru, S et al. J. Infect. Dis., DOI://10.1093/infdis/jix394 (2017)
Dynamic landscape of alternative polyadenylation during retinal development Hu, W; Li, S; Park, JY et al. Cell. Mol. Life Sci., DOI://10.1007/s00018-016-2429-1 (2017)
An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype Direk, N; Williams, S; Smith, JA et al. Biol. Psychiatry, DOI://10.1016/j.biopsych.2016.11.013 (2017)
Erratum. Gene-Environment Interactions of Circadian-Related Genes for Cardiometabolic Traits. Diabetes Care 2015;38:1456-1466 Dashti, HS; Follis, JL; Smith, CE et al. Diabetes Care, DOI://10.2337/dc17-er10a (2017)

Crystal Structures of Diaryliodonium Fluorides and Their Implications for Fluorination Mechanisms Lee, YS; Chun, JH; Hodošček, M; Pike, VW; Chemistry, DOI://10.1002/chem.201604803 (2017)
Pyrimidine Nucleotides Containing a (S)-Methanocarba Ring as P2Y6 Receptor Agonists Toti, KS; Jain, S; Ciancetta, A et al. Medchemcomm, DOI://10.1039/C7MD00397H (2017)
High-Resolution CBV-fMRI Allows Mapping of Laminar Activity and Connectivity of Cortical Input and Output in Human M1 Huber, L; Handwerker, DA; Jangraw, DC et al. Neuron, DOI://10.1016/j.neuron.2017.11.005 (2017)
CTCF-Mediated Enhancer-Promoter Interaction Is a Critical Regulator of Cell-to-Cell Variation of Gene Expression Ren, G; Jin, W; Cui, K et al. Mol. Cell, DOI://10.1016/j.molcel.2017.08.026 (2017)
Bromodomain and Extraterminal Protein Inhibitor JQ1 Suppresses Thyroid Tumor Growth in a Mouse Model Zhu, X; Enomoto, K; Zhao, L et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-16-0914 (2017)
SNF2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance and Proper Replication Taneja, N; Zofall, M; Balachandran, V et al. Mol. Cell, DOI://10.1016/j.molcel.2017.02.006 (2017)

Untimely expression of gametogenic genes in vegetative cells causes uniparental disomy Folco, HD; Chalamcharla, VR; Sugiyama, T et al. Nature, DOI://10.1038/nature21372 (2017)
KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis Murgai, M; Ju, W; Eason, M et al. Nat. Med., DOI://10.1038/nm.4400 (2017)
ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer Shukla, V; Rao, M; Zhang, H et al. Cancer Res., DOI://10.1158/0008-5472.CAN-17-0570 (2017)
NFκB Promotes Ovarian Tumorigenesis via Classical Pathways That Support Proliferative Cancer Cells and Alternative Pathways That Support ALDH+ Cancer Stem-like Cells House, CD; Jordan, E; Hernandez, L et al. Cancer Res., DOI://10.1158/0008-5472.CAN-17-0366 (2017)
The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins Wang, AH; Juan, AH; Ko, KD et al. Mol. Cell, DOI://10.1016/j.molcel.2017.09.016 (2017)
Serum starvation of ARPE-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration Rajapakse, D; Peterson, K; Mishra, S; Wistow, G; Exp. Cell Res., DOI://10.1016/j.yexcr.2017.10.036 (2017)

Molecular-based diagnosis of multiple sclerosis and its progressive stage Barbour, C; Kosa, P; Komori, M et al. Ann. Neurol., DOI://10.1002/ana.25083 (2017)
Loci associated with skin pigmentation identified in African populations Crawford, NG; Kelly, DE; Hansen, MEB et al. Science, DOI://10.1126/science.aan8433 (2017)
eIF1A residues implicated in cancer stabilize translation preinitiation complexes and favor suboptimal initiation sites in yeast Martin-Marcos, P; Zhou, F; Karunasiri, C et al. Elife, DOI://10.7554/eLife.31250 (2017)
Polygenic risk score and heritability estimates reveals a genetic relationship between ASD and OCD Guo, W; Samuels, JF; Wang, Y et al. Eur Neuropsychopharmacol, DOI://10.1016/j.euroneuro.2017.03.011 (2017)
Molecular basis of CENP-C association with the CENP-A nucleosome at yeast centromeres Xiao, H; Wang, F; Wisniewski, J et al. Genes Dev., DOI://10.1101/gad.304782.117 (2017)
Correction: The complex genetics of gait speed: genome-wide meta-analysis approach Ben-Avraham, D; Karasik, D; Verghese, J et al. Aging (Albany NY), DOI://10.18632/aging.101260 (2017)
T-Cell Transfer Therapy Targeting Mutant KRAS Rosenberg, SA; Tran, E; Robbins, PF; N. Engl. J. Med., DOI://10.1056/NEJMc1616637 (2017)
Effect of Threat on Right dlPFC Activity during Behavioral Pattern Separation Balderston, NL; Hsiung, A; Ernst, M; Grillon, C; J. Neurosci., DOI://10.1523/JNEUROSCI.0717-17.2017 (2017)
GATE: an efficient procedure in study of pleiotropic genetic associations Zhang, W; Yang, L; Tang, LL et al. BMC Genomics, DOI://10.1186/s12864-017-3928-7 (2017)
Progressive and Multi-path Holistically Nested Neural Networks for Pathological Lung Segmentation from CT Images Harrison A.P., Xu Z., George K., Lu L., Summers R.M., Mollura D.J. In: Descoteaux M., Maier-Hein L., Franz A., Jannin P., Colli, 10.1007/978-3-319-66179-7-71 (2017)
Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease Warren, CR; O'Sullivan, JF; Friesen, M et al. Cell Stem Cell, DOI://10.1016/j.stem.2017.01.010 (2017)
An Adult Mouse Thyroid Side Population Cell Line that Exhibits Enriched Epithelial-Mesenchymal Transition Murata, T; Iwadate, M; Takizawa, Y et al. Thyroid, DOI://10.1089/thy.2016.0130 (2017)
NRF1 coordinates with DNA methylation to regulate spermatogenesis Wang, J; Tang, C; Wang, Q et al. FASEB J., DOI://10.1096/fj.201700093R (2017)
Two Distinct Actin Networks Mediate Traction Oscillations to Confer Focal Adhesion Mechanosensing Wu, Z; Plotnikov, SV; Moalim, AY; Waterman, CM; Liu, J; Biophys. J., DOI://10.1016/j.bpj.2016.12.035 (2017)
'Final common pathway' of human cancer immunotherapy: targeting random somatic mutations Tran, E; Robbins, PF; Rosenberg, SA; Nat. Immunol., DOI://10.1038/ni.3682 (2017)
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 Expression Parkhurst, M; Gros, A; Pasetto, A et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-16-2680 (2017)
The Distinct Transcriptional Response of the Midgut of Amblyomma sculptum and Amblyomma aureolatum Ticks to Rickettsia rickettsii Correlates to Their Differences in Susceptibility to Infection Martins, LA; Galletti, MFBM; Ribeiro, JM et al. Front Cell Infect Microbiol, DOI://10.3389/fcimb.2017.00129 (2017)
Defining Disease, Diagnosis, and Translational Medicine within a Homeostatic Perturbation Paradigm: The National Institutes of Health Undiagnosed Diseases Program Experience Gall, T; Valkanas, E; Bello, C et al. Front Med (Lausanne), DOI://10.3389/fmed.2017.00062 (2017)
Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations Hu, Y; Tanaka, T; Zhu, J et al. J. Lipid Res., DOI://10.1194/jlr.P071860 (2017)
Binding of protofibrillar Aβ trimers to lipid bilayer surface enhances Aβ structural stability and causes membrane thinning Dong, X; Sun, Y; Wei, G; Nussinov, R; Ma, B; Phys Chem Chem Phys, DOI://10.1039/c7cp05959k (2017)
Temporal similarity perfusion mapping: A standardized and model-free method for detecting perfusion deficits in stroke Song, S; Bokkers, RPH; Luby, M et al. PLoS ONE, DOI://10.1371/journal.pone.0185552 (2017)
Genome Wide Association Study (GWAS) between Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD) Ritter, ML; Guo, W; Samuels, JF et al. Front Mol Neurosci, DOI://10.3389/fnmol.2017.00083 (2017)
Extending electrostatics of dielectric spheres to arbitrary charge distributions with applications to biosystems T. P. Doerr, O. I. Obolensky, and Yi-Kuo Yu Phys. Rev. E , doi://10.1103/PhysRevE.96.062414 (2017)
The full transcription map of mouse papillomavirus type 1 (MmuPV1) in mouse wart tissues Xue, XY; Majerciak, V; Uberoi, A et al. PLoS Pathog., DOI://10.1371/journal.ppat.1006715 (2017)

Reduced Local and Increased Long-Range Functional Connectivity of the Thalamus in Autism Spectrum Disorder Tomasi, D; Volkow, ND; Cereb. Cortex, DOI://10.1093/cercor/bhx340 (2017)
Highly Efficient Cpf1-Mediated Gene Targeting in Mice Following High Concentration Pronuclear Injection Watkins-Chow, DE; Varshney, GK; Garrett, LJ et al. G3 (Bethesda), DOI://10.1534/g3.116.038091 (2017)
CDC14A Phosphatase is Essential for Hearing and Male Fertility in Mouse and Human Imtiaz, A; Belyantseva, IA; Beirl, AJ et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddx440 (2017)
Identifying subgroups of enhanced predictive accuracy from longitudinal biomarker data using tree-based approaches: applications to fetal growth Foster, JC; Liu, D; Albert, PS; Liu, A; J R Stat Soc Ser A Stat Soc, DOI://10.1111/rssa.12182 (2017)
Effects of HLA-B27 on Gut Microbiota in Experimental Spondyloarthritis Implicate an Ecological Model of Dysbiosis Gill, T; Asquith, M; Brooks, SR; Rosenbaum, JT; Colbert, RA; Arthritis Rheumatol., DOI://10.1002/art.40405 (2017)
Generation and characterization of Kctd15 mutations in zebrafish Heffer, A; Marquart, GD; Aquilina-Beck, A; Saleem, N; Burgess, HA; Dawid, IB; PLoS ONE, DOI://10.1371/journal.pone.0189162 (2017)

Selection for long and short sleep duration in Drosophila melanogaster reveals the complex genetic network underlying natural variation in sleep Harbison, ST; Serrano Negron, YL; Hansen, NF; Lobell, AS; PLoS Genet., DOI://10.1371/journal.pgen.1007098 (2017)
Structural mechanisms of centromeric nucleosome recognition by the kinetochore protein CENP-N Chittori, S; Hong, J; Saunders, H et al. Science, DOI://10.1126/science.aar2781 (2017)
Identity-by-Descent Mapping Identifies Major Locus for Serum Triglycerides in Amerindians Largely Explained by an APOC3 Founder Mutation Hsueh, WC; Nair, AK; Kobes, S et al. Circ Cardiovasc Genet, DOI://10.1161/CIRCGENETICS.117.001809 (2017)
Detecting treatment differences in group sequential longitudinal studies with covariate adjustment Jeffries, NO; Troendle, JF; Geller, NL; Biometrics, DOI://10.1111/biom.12837 (2017)
Comparison of Additive and Polarizable Models with Explicit Treatment of Long-Range Lennard-Jones Interactions using Alkane Simulations Leonard, AN; Simmonett, AC; Pickard, FC et al. J Chem Theory Comput, DOI://10.1021/acs.jctc.7b00948 (2017)
Structural basis for nucleotide-modulated p97 association with the ER membrane Tang, WK; Zhang, T; Ye, Y; Xia, D; Cell Discov, DOI://10.1038/celldisc.2017.45 (2017)
Molecular Anatomy of the Developing Human Retina Hoshino, A; Ratnapriya, R; Brooks, MJ et al. Dev. Cell, DOI://10.1016/j.devcel.2017.10.029 (2017)
Arginine Kinases from the Precious Corals Corallium rubrum and Paracorallium japonicum: Presence of Two Distinct Arginine Kinase Gene Lineages in Cnidarians Matsuo, T; Yano, D; Uda, K; Iwasaki, N; Suzuki, T; Protein J., DOI://10.1007/s10930-017-9745-7 (2017)
The emergence and evolution of influenza A (H1α) viruses in swine in Canada and the United States Nelson, MI; Culhane, MR; Trovão, NS et al. J. Gen. Virol., DOI://10.1099/jgv.0.000924 (2017)
Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq Chen, L; Lee, JW; Chou, CL et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1710964114 (2017)
Graph theory reveals amygdala modules consistent with its anatomical subdivisions Caparelli, EC; Ross, TJ; Gu, H; Liang, X; Stein, EA; Yang, Y; Sci Rep, DOI://10.1038/s41598-017-14613-4 (2017)
Exploring Effects of Sex and Diet on Drosophila melanogaster Head Gene Expression Jaime, MDLA; Hurtado, J; Loustalot-Laclette, MR; Oliver, B; Markow, T; J Genomics, DOI://10.7150/jgen.22393 (2017)

Lasting deficit in inhibitory control with mild traumatic brain injury Xu, B; Sandrini, M; Levy, S et al. Sci Rep, DOI://10.1038/s41598-017-14867-y (2017)
CRISPR/Cas9-mediated gene knockout is insensitive to target copy number but is dependent on guide RNA potency and Cas9/sgRNA threshold expression level Yuen, G; Khan, FJ; Gao, S et al. Nucleic Acids Res., DOI://10.1093/nar/gkx843 (2017)
Structural host-microbiota interaction networks Guven-Maiorov, E; Tsai, CJ; Nussinov, R; PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1005579 (2017)
New Multiple Sclerosis Disease Severity Scale Predicts Future Accumulation of Disability Weideman, AM; Barbour, C; Tapia-Maltos, MA et al. Front Neurol, DOI://10.3389/fneur.2017.00598 (2017)
Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions Kim, J; Sturgill, D; Sebastian, R et al. Mol. Cell, DOI://10.1016/j.molcel.2017.11.021 (2017)
Dosage-Dependent Expression Variation Suppressed on the Drosophila Male X Chromosome Lee, H; Cho, DY; Wojtowicz, D et al. G3 (Bethesda), DOI://10.1534/g3.117.300400 (2017)
Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance Rosshart, SP; Vassallo, BG; Angeletti, D et al. Cell, DOI://10.1016/j.cell.2017.09.016 (2017)
Integrative Genomic Analysis of Coincident Cancer Foci Implicates CTNNB1 and PTEN Alterations in Ductal Prostate Cancer Gillard, M; Lack, J; Pontier, A et al. Eur Urol Focus, DOI://10.1016/j.euf.2017.12.003 (2017)
Dynamic regulation of lysine acetylation: the balance between acetyltransferase and deacetylase activities Hyndman, KA; Knepper, MA; Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00313.2017 (2017)
Holistic segmentation of the lung in cine MRI Kovacs, W; Hsieh, N; Roth, H et al. J Med Imaging (Bellingham), DOI://10.1117/1.JMI.4.4.041310 (2017)
Transcriptomic profiling of the human brain reveals that altered synaptic gene expression is associated with chronological aging Dillman, AA; Majounie, E; Ding, J et al. Sci Rep, DOI://10.1038/s41598-017-17322-0 (2017)
Identification of essential genes for cancer immunotherapy Patel, SJ; Sanjana, NE; Kishton, RJ et al. Nature, DOI://10.1038/nature23477 (2017)

In vivo tropism of Salmonella Typhi toxin to cells expressing a multiantennal glycan receptor Yang, YA; Lee, S; Zhao, J et al. Nat Microbiol, DOI://10.1038/s41564-017-0076-4 (2017)
Local and global anatomy of antibody-protein antigen recognition Wang, M; Zhu, D; Zhu, J; Nussinov, R; Ma, B; J. Mol. Recognit., DOI://10.1002/jmr.2693 (2017)
A digital 3D atlas of the marmoset brain based on multi-modal MRI Liu, C; Ye, FQ; Chern-Chyi Yen, C et al. Neuroimage, DOI://10.1016/j.neuroimage.2017.12.004 (2017)
Automated quality assessment of structural magnetic resonance images in children: Comparison with visual inspection and surface-based reconstruction White, T; Jansen, PR; Muetzel, RL et al. Hum Brain Mapp, DOI://10.1002/hbm.23911 (2017)
OCT4 supports extended LIF-independent self-renewal and maintenance of transcriptional and epigenetic networks in embryonic stem cells He, R; Xhabija, B; Al-Qanber, B; Kidder, BL; Sci Rep, DOI://10.1038/s41598-017-16611-y (2017)
Power Analysis for Genetic Association Test (PAGEANT) provides insights to challenges for rare variant association studies Derkach, A; Zhang, H; Chatterjee, N; Bioinformatics, DOI://10.1093/bioinformatics/btx770 (2017)

Demystifying P2Y1 Receptor Ligand Recognition through Docking and Molecular Dynamics Analyses Ciancetta, A; O'Connor, RD; Paoletta, S; Jacobson, KA; J Chem Inf Model, DOI://10.1021/acs.jcim.7b00528 (2017)
A STAT3-dependent transcriptional circuitry inhibits cytotoxic gene expression in T cells Ciucci, T; Vacchio, MS; Bosselut, R; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1711160114 (2017)
Landscape of immunogenic tumor antigens in successful immunotherapy of virally induced epithelial cancer Stevanović, S; Pasetto, A; Helman, SR et al. Science, DOI://10.1126/science.aak9510 (2017)
HiHiMap: single-cell quantitation of histones and histone posttranslational modifications across the cell cycle by high-throughput imaging Zane, L; Chapus, F; Pegoraro, G; Misteli, T; Mol. Biol. Cell, DOI://10.1091/mbc.E16-12-0870 (2017)
Natural Language Processing for Large-Scale Medical Image Analysis Using Deep Learning Hoo-Chang Shin, Le Lu, Ronald M. Summers in Deep Learning for Medical Image Analysis, Elsevier , (p405-421) (2017)
Allometric Analysis Detects Brain Size-Independent Effects of Sex and Sex Chromosome Complement on Human Cerebellar Organization Mankiw, C; Park, MTM; Reardon, PK et al. J. Neurosci., DOI://10.1523/JNEUROSCI.2158-16.2017 (2017)

Excessive burden of lysosomal storage disorder gene variants in Parkinson's disease Robak, LA; Jansen, IE; van Rooij, J et al. Brain, DOI://10.1093/brain/awx285 (2017)
Insights into functions of the H channel of cytochrome c oxidase from atomistic molecular dynamics simulations Sharma, V; Jambrina, PG; Kaukonen, M; Rosta, E; Rich, PR; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1708628114 (2017)
Conventional and pioneer modes of glucocorticoid receptor interaction with enhancer chromatin in vivo Johnson, TA; Chereji, RV; Stavreva, DA; Morris, SA; Hager, GL; Clark, DJ; Nucleic Acids Res., DOI://10.1093/nar/gkx1044 (2017)
A joint model for multivariate hierarchical semicontinuous data with replications Kassahun-Yimer, W; Albert, PS; Lipsky, LM; Nansel, TR; Liu, A; Stat Methods Med Res, DOI://10.1177/0962280217738141 (2017)
Phosphorylated Calmodulin Promotes PI3K Activation by Binding to the SH2 Domains Zhang, M; Jang, H; Gaponenko, V; Nussinov, R; Biophys. J., DOI://10.1016/j.bpj.2017.09.008 (2017)
Prediction of Host-Pathogen Interactions for Helicobacter pylori by Interface Mimicry and Implications to Gastric Cancer Guven-Maiorov, E; Tsai, CJ; Ma, B; Nussinov, R; J. Mol. Biol., DOI://10.1016/j.jmb.2017.10.023 (2017)
Physiological and pathophysiological implications of PGE2 and the PGE2 synthases in the kidney Wang, J; Liu, M; Zhang, X; Yang, G; Chen, L; Prostaglandins Other Lipid Mediat., DOI://10.1016/j.prostaglandins.2017.10.006 (2017)
Genetic Analysis of Inherited Retinal Diseases in Indigenous Southern African Populations Lisa Jane Roberts (R. Ramesar & A. Swaroop, thesis advisors) PhD thesis, University of Cape Town (2017)
Independence between pre-mRNA splicing and DNA methylation in an isogenic minigene resource Kyster K. Nanan, Cody Ocheltree, David Sturgill, Mariana D. Mandler, Maria Prigge, Garima Varma, Shalini Oberdoerffer Nucleic Acids Res., doi://10.1093/nar/gkx900 (2017)
Analysis of Gap Times Based on Panel Count Data With Informative Observation Times and Unknown Start Time Ling Ma and Rajeshwari Sundaram J. Am. Stat. Assoc, doi://10.1080/01621459.2016.1246369 (2017)
Multimodal mapping of the brain's functional connectivity and the adult outcome of attention deficit hyperactivity disorder Sudre, G; Szekely, E; Sharp, W; Kasparek, S; Shaw, P; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1705229114 (2017)
The Kölliker-Fuse nucleus orchestrates the timing of expiratory abdominal nerve bursting Barnett, WH; Jenkin, SEM; Milsom, WK et al. J. Neurophysiol., DOI://10.1152/jn.00499.2017 (2017)

PaRSnIP: Sequence-Based Protein Solubility Prediction using Gradient Boosting Machine Rawi, R; Mall, R; Kunji, K; Shen, CH; Kwong, PD; Chuang, GY; Bioinformatics, DOI://10.1093/bioinformatics/btx662 (2017)
Subset- and tissue-defined STAT5 thresholds control homeostasis and function of innate lymphoid cells Villarino, AV; Sciumè, G; Davis, FP et al. J. Exp. Med., DOI://10.1084/jem.20150907 (2017)
Unpicking the determinants of amide NHO[double bond, length as m-dash]C hydrogen bond strength with diphenylacetylene molecular balances Luccarelli, J; Jones, IM; Thompson, S; Hamilton, AD; Org. Biomol. Chem., DOI://10.1039/c7ob02026k (2017)
Peptide dimerization-dissociation rates from replica exchange molecular dynamics Leahy, CT; Kells, A; Hummer, G; Buchete, NV; Rosta, E; J Chem Phys, DOI://10.1063/1.5004774 (2017)
Identification of UT-A1-and AQP2 interacting proteins in rat inner medullary collecting duct Chou, CL; Hwang, G; Hageman, DJ et al. Am. J. Physiol., Cell Physiol., DOI://10.1152/ajpcell.00082.2017 (2017)
Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex Guo, TW; Bartesaghi, A; Yang, H et al. Cell, DOI://10.1016/j.cell.2017.09.006 (2017)

How Many Protein Sequences Fold to a Given Structure? A Coevolutionary Analysis Tian, P; Best, RB; Biophys. J., DOI://10.1016/j.bpj.2017.08.039 (2017)
The FUT2 secretor variant p.Trp154Ter influences serum vitamin B12 concentration via holo-haptocorrin, but not holo-transcobalamin, and is associated with haptocorrin glycosylation Velkova, A; Diaz, JEL; Pangilinan, F et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddx369 (2017)
A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency Aoki, M; Hayashi, H; Rao, KV et al. Elife, DOI://10.7554/eLife.28020 (2017)
A functional connectivity-based neuromarker of sustained attention generalizes to predict recall in a reading task Jangraw, DC; Gonzalez-Castillo, J; Handwerker, DA et al. Neuroimage, DOI://10.1016/j.neuroimage.2017.10.019 (2017)
MELD: Mixed effects for large datasets Nielson, DM; Sederberg, PB; PLoS ONE, DOI://10.1371/journal.pone.0182797 (2017)
MicroRNA Signature of Cigarette Smoking and Evidence for a Putative Causal Role of MicroRNAs in Smoking-Related Inflammation and Target Organ Damage Willinger, CM; Rong, J; Tanriverdi, K et al. Circ Cardiovasc Genet, DOI://10.1161/CIRCGENETICS.116.001678 (2017)

De novo Assembly of a New Solanum pennellii Accession Using Nanopore Sequencing Schmidt, MH; Vogel, A; Denton, AK et al. Plant Cell, DOI://10.1105/tpc.17.00521 (2017)
Rapid Nanopore Sequencing of Plasmids and Resistance Gene Detection in Clinical Isolates Lemon, JK; Khil, PP; Frank, KM; Dekker, JP; J. Clin. Microbiol., DOI://10.1128/JCM.01069-17 (2017)
Molecular Dynamics Simulations of Ceramide and Ceramide-Phosphatidylcholine Bilayers Wang, E; Klauda, JB; J Phys Chem B, DOI://10.1021/acs.jpcb.7b08967 (2017)
CHD7 deficiency delays leukemogenesis in mice induced by CBFB-MYH11 Zhen, T; Kwon, E; Zhao, L et al. Blood, DOI://10.1182/blood-2017-04-780106 (2017)
TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF Seberg, HE; Van Otterloo, E; Loftus, SK et al. PLoS Genet., DOI://10.1371/journal.pgen.1006636 (2017)
Molecular architecture underlying fluid absorption by the developing inner ear Honda, K; Kim, SH; Kelly, MC et al. Elife, DOI://10.7554/eLife.26851 (2017)

Moderate blast exposure alters gene expression and levels of amyloid precursor protein Gill, J; Cashion, A; Osier, N et al. Neurol Genet, DOI://10.1212/NXG.0000000000000186 (2017)
Preclinical testing of the glycogen synthase kinase-3β inhibitor tideglusib for rhabdomyosarcoma Bharathy, N; Svalina, MN; Settelmeyer, TP et al. Oncotarget, DOI://10.18632/oncotarget.18520 (2017)
Novel near-diploid ovarian cancer cell line derived from a highly aneuploid metastatic ovarian tumor Rozenblum, E; Sotelo-Silveira, JR; Kim, GY et al. PLoS ONE, DOI://10.1371/journal.pone.0182610 (2017)
SMYD5 controls heterochromatin and chromosome integrity during embryonic stem cell differentiation Kidder, BL; He, R; Wangsa, D et al. Cancer Res., DOI://10.1158/0008-5472.CAN-17-0828 (2017)
GRL-09510, a Unique P2-Crown-Tetrahydrofuranylurethane -Containing HIV-1 Protease Inhibitor, Maintains Its Favorable Antiviral Activity against Highly-Drug-Resistant HIV-1 Variants in vitro Amano, M; Miguel Salcedo-Gómez, P; Yedidi, RS et al. Sci Rep, DOI://10.1038/s41598-017-12052-9 (2017)
Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains Murray, DT; Kato, M; Lin, Y et al. Cell, DOI://10.1016/j.cell.2017.08.048 (2017)
Evaluation and comparison of predictive individual-level general surrogates Erin E. Gabriel, Michael C. Sachs, M. Elizabeth Halloran Biostatistics, doi://10.1093/biostatistics/kxx037 (2017)
Piecewise Polynomial Approximations To The Icrp 116 Effective Dose Coefficients: Photons And Neutrons M. M. Mille N. E. Hertel P. M. Bergstrom C. Lee Radiation Protection Dosimetry, doi://10.1093/rpd/ncx112 (2017)
Estimating onset time from longitudinal and cross-sectional data with an application to estimating gestational age from longitudinal maternal anthropometry during pregnancy and neonatal anthropometry at birth Ana Maria Ortega-Villa, Katherine L. Grantz, Paul S. Albert J. Roy. Stat. Soc., DOI: 10.1111/rssa.12312 (2017)
Decline of long-range temporal correlations in the human brain during sustained wakefulness Meisel, C; Bailey, K; Achermann, P; Plenz, D; Sci Rep, DOI://10.1038/s41598-017-12140-w (2017)
Mechanisms of recognition of amyloid-β (Aβ) monomer, oligomer, and fibril by homologous antibodies Zhao, J; Nussinov, R; Ma, B; J. Biol. Chem., DOI://10.1074/jbc.M117.801514 (2017)
Topological structure determination of RNA using small angle X-ray scattering Bhandari, YR; Fan, L; Fang, X et al. J. Mol. Biol., DOI://10.1016/j.jmb.2017.09.006 (2017)

Nuclease activity gives an edge to host-defense peptide piscidin 3 over piscidin 1, rendering it more effective against persisters and biofilms Libardo, MDJ; Bahar, AA; Ma, B et al. FEBS J., DOI://10.1111/febs.14263 (2017)
Atropos: specific, sensitive, and speedy trimming of sequencing reads Didion, JP; Martin, M; Collins, FS; PeerJ, DOI://10.7717/peerj.3720 (2017)
Direct comparison of performance of single nucleotide variant calling in human genome with alignment-based and assembly-based approaches Wu, L; Yavas, G; Hong, H; Tong, W; Xiao, W; Sci Rep, DOI://10.1038/s41598-017-10826-9 (2017)
Temporal interpolation alters motion in fMRI scans: Magnitudes and consequences for artifact detection Power, JD; Plitt, M; Kundu, P; Bandettini, PA; Martin, A; PLoS ONE, DOI://10.1371/journal.pone.0182939 (2017)
Paired Expression Analysis of Tumor Cell Surface Antigens Orentas, RJ; Sindiri, S; Duris, C et al. Front Oncol, DOI://10.3389/fonc.2017.00173 (2017)
High-precision registration between zebrafish brain atlases using symmetric diffeomorphic normalization Marquart, GD; Tabor, KM; Horstick, EJ et al. Gigascience, DOI://10.1093/gigascience/gix056 (2017)
Global Inhibition with Specific Activation: How p53 and MYC Redistribute the Transcriptome in the DNA Double-Strand Break Response Porter, JR; Fisher, BE; Baranello, L et al. Mol. Cell, DOI://10.1016/j.molcel.2017.07.028 (2017)
Regulation of Noncoding Transcriptome in Developing Photoreceptors by Rod Differentiation Factor NRL Zelinger, L; Karakülah, G; Chaitankar, V et al. Invest. Ophthalmol. Vis. Sci., DOI://10.1167/iovs.17-21805 (2017)
Higher-than-expected population prevalence of potentially pathogenic germline TP53 variants in individuals unselected for cancer history de Andrade, KC; Mirabello, L; Stewart, DR et al. Hum. Mutat., DOI://10.1002/humu.23320 (2017)
Novel signal transducer and activator of transcription 1 mutation disrupts small ubiquitin-related modifier conjugation causing gain of function Sampaio, EP; Ding, L; Rose, SR et al. J. Allergy Clin. Immunol., DOI://10.1016/j.jaci.2017.07.027 (2017)
Statistical Methods for Standard Membrane-Feeding Assays to Measure Transmission Blocking or Reducing Activity in Malaria Bruce J. Swihart, Michael P. Fay & Kazutoyo Miura Journal of the American Statistical Association, doi://10.1080/01621459.2017.1356313 (2017)
The LDB1 Complex Co-opts CTCF for Erythroid Lineage-Specific Long-Range Enhancer Interactions Lee, J; Krivega, I; Dale, RK; Dean, A; Cell Rep, DOI://10.1016/j.celrep.2017.05.072 (2017)

MLL4 prepares the enhancer landscape for Foxp3 induction via chromatin looping Placek, K; Hu, G; Cui, K et al. Nat. Immunol., DOI://10.1038/ni.3812 (2017)
Therapeutic Antibodies to Ganglioside GD2 Evolved from Highly Selective Germline Antibodies Sterner, E; Peach, ML; Nicklaus, MC; Gildersleeve, JC; Cell Rep, DOI://10.1016/j.celrep.2017.07.050 (2017)
High-SETD8 inactivates p53 in neuroblastoma Veschi, V; Thiele, CJ; Oncoscience, DOI://10.18632/oncoscience.344 (2017)
Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation Kieffer-Kwon, KR; Nimura, K; Rao, SSP et al. Mol. Cell, DOI://10.1016/j.molcel.2017.07.013 (2017)
Anti-Inflammatory Chromatinscape Suggests Alternative Mechanisms of Glucocorticoid Receptor Action Oh, KS; Patel, H; Gottschalk, RA et al. Immunity, DOI://10.1016/j.immuni.2017.07.012 (2017)
Hydroxyl-radical footprinting combined with molecular modeling identifies unique features of DNA conformation and nucleosome positioning Alexey K. Shaytan, Hua Xiao, Grigoriy A. Armeev, Carl Wu, David Landsman, Anna R. Panchenko Nucleic Acids Res. , doi://10.1093/nar/gkx616 (2017)

Functional Subpopulations of Neurons in a Macaque Face Patch Revealed by Single-Unit fMRI Mapping Soo Hyun Park, Brian E. Russ, David B.T. McMahon, Kenji W. Koyano, Rebecca A. Berman, David A. Leopold Neuron, doi://10.1016/j.neuron.2017.07.014 (2017)
Palmitoylation contributes to membrane curvature in Influenza A virus assembly and hemagglutinin-mediated membrane fusion Chlanda, P; Mekhedov, E; Waters, H et al. J. Virol., DOI://10.1128/JVI.00947-17 (2017)
Survival in adults and children with systemic lupus erythematosus: a systematic review and Bayesian meta-analysis of studies from 1950 to 2016 Tektonidou, MG; Lewandowski, LB; Hu, J; Dasgupta, A; Ward, MM; Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2017-211663 (2017)
Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity Monahan, Z; Ryan, VH; Janke, AM et al. EMBO J., DOI://10.15252/embj.201696394 (2017)
Stabilization of diastolic calcium signal via calcium pump regulation of complex local calcium releases and transient decay in a computational model of cardiac pacemaker cell with individual release channels Maltsev, AV; Maltsev, VA; Stern, MD; PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1005675 (2017)
A very simple, re-executable neuroimaging publication Ghosh, SS; Poline, JB; Keator, DB et al. F1000Res, DOI://10.12688/f1000research.10783.2 (2017)

A Novel Method To Estimate Lymphocyte Dose And Application To Pediatric And Young Adult Ct Patients In The United Kingdom Choonsik Lee, Lindsay M. Morton, Amy Berrington de Gonzalez Radiation Dosimetry, doi://10.1093/rpd/ncx084 (2017)
Does accounting for seizure frequency variability increase clinical trial power Goldenholz, DM; Goldenholz, SR; Moss, R et al. Epilepsy Res., DOI://10.1016/j.eplepsyres.2017.07.013 (2017)
Katanin spiral and ring structures shed light on power stroke for microtubule severing Zehr, E; Szyk, A; Piszczek, G; Szczesna, E; Zuo, X; Roll-Mecak, A; Nat. Struct. Mol. Biol., DOI://10.1038/nsmb.3448 (2017)
A common SLC26A4-linked haplotype underlying non-syndromic hearing loss with enlargement of the vestibular aqueduct Chattaraj, P; Munjal, T; Honda, K et al. J. Med. Genet., DOI://10.1136/jmedgenet-2017-104721 (2017)
Task-based dynamic functional connectivity: Recent findings and open questions Gonzalez-Castillo, J; Bandettini, PA; Neuroimage, DOI://10.1016/j.neuroimage.2017.08.006 (2017)
Genetic background-dependent role of Egr1 for eyelid development Oh, J; Wang, Y; Chen, S et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1705848114 (2017)
A Two-Step Approach for Analysis of Nonignorable Missing Outcomes in Longitudinal Regression: an Application to Upstate KIDS Study Liu, D; Yeung, EH; McLain, AC; Xie, Y; Buck Louis, GM; Sundaram, R; Paediatr Perinat Epidemiol, DOI://10.1111/ppe.12382 (2017)
The prevalence of DICER1 pathogenic variation in population databases Kim, J; Field, A; Schultz, KAP; Hill, DA; Stewart, DR; Int. J. Cancer, DOI://10.1002/ijc.30907 (2017)
Systematic Investigation of Multi-TLR Sensing Identifies Regulators of Sustained Gene Activation in Macrophages Lin, B; Dutta, B; Fraser, IDC; Cell Syst, DOI://10.1016/j.cels.2017.06.014 (2017)
Combining Multiple Resting-State fMRI Features during Classification: Optimized Frameworks and Their Application to Nicotine Addiction Ding, X; Yang, Y; Stein, EA; Ross, TJ; Front Hum Neurosci, DOI://10.3389/fnhum.2017.00362 (2017)
Neanderthal-Derived Genetic Variation Shapes Modern Human Cranium and Brain Gregory, MD; Kippenhan, JS; Eisenberg, DP et al. Sci Rep, DOI://10.1038/s41598-017-06587-0 (2017)
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney Wain, LV; Vaez, A; Jansen, R et al. Hypertension, DOI://10.1161/HYPERTENSIONAHA.117.09438 (2017)

Genome Organization Drives Chromosome Fragility Canela, A; Maman, Y; Jung, S et al. Cell, DOI://10.1016/j.cell.2017.06.034 (2017)
Genomic and metabolic characterization of a chromophobe renal cell carcinoma cell line model (UOK276) Yang, Y; Vocke, CD; Ricketts, CJ et al. Genes Chromosomes Cancer, DOI://10.1002/gcc.22476 (2017)
A population-specific reference panel empowers genetic studies of Anabaptist populations Hou, L; Kember, RL; Roach, JC et al. Sci Rep, DOI://10.1038/s41598-017-05445-3 (2017)
Global alteration of the drug-binding pocket of human P-glycoprotein (ABCB1) by substitution of fifteen conserved residues reveals a negative correlation between substrate size and transport efficiency Vahedi, S; Chufan, EE; Ambudkar, SV; Biochem. Pharmacol., DOI://10.1016/j.bcp.2017.07.014 (2017)
Histone demethylases UTX and JMJD3 are required for NKT cell development in mice Northrup, D; Yagi, R; Cui, K et al. Cell Biosci, DOI://10.1186/s13578-017-0152-8 (2017)
How to control for unmeasured confounding in an observational time-to-event study with exposure incidence information: the treatment choice Cox model Troendle, J; Leifer, E; Zhang, Z; Yong, S; Tewes, H Stat. Med. , DOI: 10.1002/sim.7377 (2017)
Chromosome 3q22-29 amplification is linked to increased expression of multiple genes in key pathways deregulated in head and neck cancer tumors and cell lines Cheng H, Yang X, Si H et al. Cancer Research, DOI: 10.1158/1538-7445.AM2017-4374 (2017)
Facultative CTCF sites moderate mammary super-enhancer activity and regulate juxtaposed gene in non-mammary cells Willi, M; Yoo, KH; Reinisch, F et al. Nat Commun, DOI://10.1038/ncomms16069 (2017)
Deep Learning and Convolutional Neural Networks for Medical Image Computing: Precision Medicine, High Performance and Large-Scale Datasets edited by Le Lu, Yefeng Zheng, Gustavo Carneiro, Lin Yang Advances in Computer Vision and Pattern Recognition (2017)
Scaffolding of long read assemblies using long range contact information Ghurye, J; Pop, M; Koren, S; Bickhart, D; Chin, CS; BMC Genomics, DOI://10.1186/s12864-017-3879-z (2017)
Proper joint analysis of summary association statistics requires the adjustment of heterogeneity in SNP coverage pattern Han Zhang, William Wheeler, Lei Song, Kai Yu Briefings in Bioinformatics, doi://10.1093/bib/bbx072 (2017)
Oncogenic Activation of the RNA Binding Protein NELFE and MYC Signaling in Hepatocellular Carcinoma Dang, H; Takai, A; Forgues, M et al. Cancer Cell, DOI://10.1016/j.ccell.2017.06.002 (2017)

Longitudinal profiling reveals a persistent intestinal dysbiosis triggered by conventional anti-tuberculosis therapy Namasivayam, S; Maiga, M; Yuan, W et al. Microbiome, DOI://10.1186/s40168-017-0286-2 (2017)
Staphylococcus aureus and Staphylococcus epidermidis strain diversity underlying pediatric atopic dermatitis Byrd, AL; Deming, C; Cassidy, SKB et al. Sci Transl Med, DOI://10.1126/scitranslmed.aal4651 (2017)
Computer algorithms for automated detection and analysis of local Ca2+ releases in spontaneously beating cardiac pacemaker cells Maltsev, AV; Parsons, SP; Kim, MS et al. PLoS ONE, DOI://10.1371/journal.pone.0179419 (2017)
Genomic Analyses Reveal the Influence of Geographic Origin, Migration, and Hybridization on Modern Dog Breed Development Parker, HG; Dreger, DL; Rimbault, M et al. Cell Rep, DOI://10.1016/j.celrep.2017.03.079 (2017)
Clusters of calcium release channels harness the Ising phase transition to confine their elementary intracellular signals Maltsev, AV; Maltsev, VA; Stern, MD; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1701409114 (2017)
Pattern-mixture models with incomplete informative cluster size: application to a repeated pregnancy study Ashok Chaurasia, Danping Liu, Paul S. Albert Royal Statistical Society: Applied Statistics, DOI: 10.1111/rssc.12226 (2017)

Biopsy-guided learning with deep convolutional neural networks for Prostate Cancer detection on multiparametric MRI Tsehay Y, Lay N et al Biomedical Imaging, doi://10.1109/ISBI.2017.7950602 (2017)
Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers Steve TR, Li W-Q, Shi J, et al. Hum. Mol. Genet. , DOI: https://doi.org/10.1093/hmg/ddx188 (2017)
Structural studies of the endotoxin sensing protein Factor C McClymont, Karen PhD thesis, University of Glasgow (2017)
Type 2 diabetes, glucose, insulin, BMI, and ischemic stroke subtypes: Mendelian randomization study Larsson, SC; Scott, RA; Traylor, M et al. Neurology, DOI://10.1212/WNL.0000000000004173 (2017)
Whole-Genome Sequencing Overrules a Suspected Case of Carbapenem-Resistant Enterobacter cloacae Transmission Chen, M; Conlan, S; Lau, AF et al. J. Clin. Microbiol., DOI://10.1128/JCM.00915-17 (2017)
Defining the Neural Substrate of the Adult Outcome of Childhood ADHD: A Multimodal Neuroimaging Study of Response Inhibition Szekely, E; Sudre, GP; Sharp, W; Leibenluft, E; Shaw, P; Am J Psychiatry, DOI://10.1176/appi.ajp.2017.16111313 (2017)

Growth Inhibition of Colon Cancer and Melanoma Cells by Versiol Derivatives from a Paraconiothyrium Species Cho, N; Ransom, TT; Sigmund, J et al. J. Nat. Prod., DOI://10.1021/acs.jnatprod.7b00170 (2017)
De novo transcriptome assembly of loggerhead sea turtle nesting of the Colombian Caribbean Hernández-Fernández, J; Pinzón, A; Mariño-Ramírez, L; Genom Data, DOI://10.1016/j.gdata.2017.06.005 (2017)
Conserved and species-specific molecular denominators in mammalian skeletal muscle aging Mercken, EM; Capri, M; Carboneau, BA et al. NPJ Aging Mech Dis, DOI://10.1038/s41514-017-0009-8 (2017)
Pandemic (H1N1) 2009 influenza A virus infection associated with respiratory signs in sloth bears (Melursus ursinus) Boedeker, NC; Nelson, MI; Killian, ML; Torchetti, MK; Barthel, T; Murray, S; Zoonoses Public Health, DOI://10.1111/zph.12370 (2017)
Characterizing cis-regulatory variation in the transcriptome of histologically normal and tumor-derived pancreatic tissues Zhang, M; Lykke-Andersen, S; Zhu, B et al. Gut, DOI://10.1136/gutjnl-2016-313146 (2017)
Actin Filament Strain Promotes Severing and Cofilin Dissociation Schramm, AC; Hocky, GM; Voth, GA; Blanchoin, L; Martiel, JL; De La Cruz, EM; Biophys. J., DOI://10.1016/j.bpj.2017.05.016 (2017)

Genome-Wide Association Study to Identify Susceptibility Loci That Modify Radiation-Related Risk for Breast Cancer After Childhood Cancer Lindsay M. Morton Joshua N. Sampson Gregory T. Armstrong et al. J. Natl. Cancer. Inst., DOI: https://doi.org/10.1093/jnci/djx058 (2017)
Insights into the binding mode of MEK type-III inhibitors. A step towards discovering and designing allosteric kinase inhibitors across the human kinome Zhao, Z; Xie, L; Bourne, PE; PLoS ONE, DOI://10.1371/journal.pone.0179936 (2017)
The Transcription Factor T-bet Limits Amplification of Type I IFN Transcriptome and Circuitry in T Helper 1 Cells Iwata, S; Mikami, Y; Sun, HW et al. Immunity, DOI://10.1016/j.immuni.2017.05.005 (2017)
Flexible-Body Motions of Calmodulin and the Farnesylated Hypervariable Region Yield a High-Affinity Interaction Enabling K-Ras4B Membrane Extraction Jang, H; Banerjee, A; Chavan, T; Gaponenko, V; Nussinov, R; J. Biol. Chem., DOI://10.1074/jbc.M117.785063 (2017)
The Transcriptome of the Didelphis virginiana Opossum Kidney OK Proximal Tubule Cell Line Eshbach, ML; Sethi, R; Avula, R et al. Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00228.2017 (2017)
Graphite-Templated Amyloid Nanostructures Formed by A Potential Pentapeptide Inhibitor for Alzheimer's disease: A Combined Study of Real-Time Atomic Force Microscopy and Molecular Dynamics Simulations Li, N; Jang, H; Yuan, M et al. Langmuir, DOI://10.1021/acs.langmuir.7b00414 (2017)

Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study Noyce, AJ; Kia, DA; Hemani, G et al. PLoS Med., DOI://10.1371/journal.pmed.1002314 (2017)
Socioeconomic disadvantage, gestational immune activity, and neurodevelopment in early childhood Gilman, SE; Hornig, M; Ghassabian, A et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1617698114 (2017)
Workflow and web application for annotating NCBI BioProject transcriptome data Vera Alvarez, R; Medeiros Vidal, N; Garzón-Martínez, GA; Barrero, LS; Landsman, D; Mariño-Ramírez, L; Database (Oxford), DOI://10.1093/database/bax008 (2017)
NeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases Blauwendraat, C; Faghri, F; Pihlstrom, L et al. Neurobiol. Aging, DOI://10.1016/j.neurobiolaging.2017.05.009 (2017)
Mitochondrial respiration and ROS emission during β-oxidation in the heart: An experimental-computational study Cortassa, S; Sollott, SJ; Aon, MA; PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1005588 (2017)
Overexpression of ATP-Binding Cassette Subfamily G Member 2 Confers Resistance to Phosphatidylinositol 3-Kinase Inhibitor PF-4989216 in Cancer Cells Wu, CP; Murakami, M; Hsiao, SH et al. Mol. Pharm., DOI://10.1021/acs.molpharmaceut.7b00277 (2017)

Intrinsic protein disorder in oncogenic KRAS signaling Nussinov, R; Jang, H; Tsai, CJ et al. Cell. Mol. Life Sci., DOI://10.1007/s00018-017-2564-3 (2017)
Monte Carlo simulations of randomized clinical trials in epilepsy DM Goldenholz, J Tharayil, R Moss, E Myers, WH Theodore Annals of Clinical and Translational Neurology, DOI: 10.1002/acn3.426 (2017)
Heightened amygdala responsiveness in s-carriers of 5-HTTLPR genetic polymorphism reflects enhanced cortical rather than subcortical inputs: An MEG study Luo, Q; Holroyd, T; Mitchell, D et al. Hum Brain Mapp, DOI://10.1002/hbm.23616 (2017)
Prostate Cancer: A Correlative Study of Multiparametric MR Imaging and Digital Histopathology Kwak, JT; Sankineni, S; Xu, S et al. Radiology, DOI://10.1148/radiol.2017160906 (2017)
Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31 Freeman, LA; Demosky, SJ; Konaklieva, M et al. J. Pharmacol. Exp. Ther., DOI://10.1124/jpet.117.240457 (2017)
Mediator binds to boundaries of chromosomal interaction domains and to proteins involved in DNA looping, RNA metabolism, chromatin remodeling, and actin assembly Chereji, RV; Bharatula, V; Elfving, N et al. Nucleic Acids Res., DOI://10.1093/nar/gkx491 (2017)
High-fidelity PCR enzyme with DNA-binding domain facilitates de novo gene synthesis Dolgova, AS; Stukolova, OA; 3 Biotech, DOI://10.1007/s13205-017-0745-2 (2017)
Release of Cytochrome C from Bax Pores at the Mitochondrial Membrane Zhang, M; Zheng, J; Nussinov, R; Ma, B; Sci Rep, DOI://10.1038/s41598-017-02825-7 (2017)
Threat of shock increases excitability and connectivity of the intraparietal sulcus Balderston, NL; Hale, E; Hsiung, A et al. Elife, DOI://10.7554/eLife.23608 (2017)
Identification and Analysis of Protein Phosphorylation by Mass Spectrometry DE McNulty, TW Sikorski, RS Annan in 'Analysis of Protein Post-Translational Modifications by , ed John R. Griffiths, Richard D. Unwin. Wiley (2017)
Whole-brain connectivity dynamics reflect both task-specific and individual-specific modulation: A multitask study Xie, H; Calhoun, VD; Gonzalez-Castillo, J et al. Neuroimage, DOI://10.1016/j.neuroimage.2017.05.050 (2017)
Combined single molecule experimental and computational approaches for understanding the unfolding pathway of a viral translation enhancer that participates in a conformational switch Le, MT; Kasprzak, WK; Shapiro, BA; Simon, AE; RNA Biol, DOI://10.1080/15476286.2017.1325069 (2017)

Phosphorylated SIRT1 associates with replication origins to prevent excess replication initiation and preserve genomic stability Utani, K; Fu, H; Jang, SM et al. Nucleic Acids Res., DOI://10.1093/nar/gkx468 (2017)
Tumor-Infiltrating Lymphocyte Therapy and Neoantigens Robbins, PF Cancer J, DOI://10.1097/PPO.0000000000000267 (2017)
PDEδ Binding to Ras Isoforms Provides a Route to Proper Membrane Localization Muratcioglu, S; Jang, H; Gursoy, A; Keskin, O; Nussinov, R; J Phys Chem B, DOI://10.1021/acs.jpcb.7b03035 (2017)
Deficiency of Complement 1r Subcomponent in Early-Onset Systemic Lupus Erythematosus: The Role of Disease-Modifying Alleles in a Monogenic Disease Demirkaya, E; Zhou, Q; Smith, CK et al. , DOI://10.1002/art.40158 (2017)
Dynamic enhancer function in the chromatin context Goldstein, I; Hager, GL; Wiley Interdiscip Rev Syst Biol Med, DOI://10.1002/wsbm.1390 (2017)
Bivariate Genomic Footprinting Detects Changes in Transcription Factor Activity Baek, S; Goldstein, I; Hager, GL; Cell Rep, DOI://10.1016/j.celrep.2017.05.003 (2017)

Mechanics of post-fusion exocytotic vesicle Stephens, T; Wu, Z; Liu, J; Phys Biol, DOI://10.1088/1478-3975/aa6ad6 (2017)
Brownian ratchet mechanisms of ParA-mediated partitioning Hu, L; Vecchiarelli, AG; Mizuuchi, K; Neuman, KC; Liu, J; Plasmid, DOI://10.1016/j.plasmid.2017.05.002 (2017)
BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency Afzali, B; Grönholm, J; Vandrovcova, J et al. Nat. Immunol., DOI://10.1038/ni.3753 (2017)
Pathology of callosal damage in ALS: An ex-vivo, 7 T diffusion tensor MRI study Agustin M. Cardenas, Joelle E. Sarlls, Justin Y. Kwan, Devin Bageac, Zachary S. Gala, Laura E. Danielian, Abhik Ray-Chaudhury, Hao-Wei Wang, Karla L. Miller, Sean Foxley, Saad Jbabdid, Robert C. Welsh, Mary Kay Floeter NeuroImage: Clinical, doi://10.1016/j.nicl.2017.04.024 (2017)
Unsupervised Joint Mining of Deep Features and Image Labels for Large-Scale Radiology Image Categorization and Scene Recognition Xiaosong Wang, Le Lu, Hoo-chang Shin, Lauren Kim, Mohammadhadi Bagheri, Isabella Nogues, Jianhua Yao, Ronald M. Summers IEEE Winter Conference on Applications of Computer Vision, DOI 10.1109/WACV.2017.116 (2017)
Simulating clinical trials with and without intracranial EEG data Goldenholz D, Tharayil J, Kuzniecky R, et al. Epilepsia Open, DOI: 10.1002/epi4.12038 (2017)

Drosophila melanogaster positive transcriptional elongation factors regulate metabolic and sex-biased expression in adults Yang, H; Basquin, D; Pauli, D; Oliver, B; BMC Genomics, DOI://10.1186/s12864-017-3755-x (2017)
Pias3 is necessary for dorso-ventral patterning and visual response of retinal cones but is not required for rod photoreceptor differentiation Campla, CK; Breit, H; Dong, L; Gumerson, JD; Roger, JE; Swaroop, A; Biol Open, DOI://10.1242/bio.024679 (2017)
Human ancestry correlates with language and reveals that race is not an objective genomic classifier Baker, JL; Rotimi, CN; Shriner, D; Sci Rep, DOI://10.1038/s41598-017-01837-7 (2017)
Conformational Changes in Active and Inactive States of Human PP2Cα Characterized by Hydrogen/Deuterium Exchange-Mass Spectrometry Mazur, SJ; Gallagher, ES; Debnath, S et al. Biochemistry, DOI://10.1021/acs.biochem.6b01220 (2017)
A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated with Reduced Energy Expenditure in American Indians Piaggi, P; Masindova, I; Muller, YL et al. Diabetes, DOI://10.2337/db16-1565 (2017)
Molecular codes for cell type specification in Brn3 retinal ganglion cells Sajgo, S; Ghinia, MG; Brooks, M et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1618551114 (2017)

A population MRI brain template and analysis tools for the macaque Seidlitz, J; Sponheim, C; Glen, D et al. Neuroimage, DOI://10.1016/j.neuroimage.2017.04.063 (2017)
Calmodulin and PI3K Signaling in KRAS Cancers Nussinov, R; Wang, G; Tsai, CJ et al. Trends Cancer, DOI://10.1016/j.trecan.2017.01.007 (2017)
Median Analysis of Repeated Measures Associated with Recurrent Events in Presence of Terminal Event Sundaram, R; Ma, L; Ghoshal, S; Int J Biostat, DOI://10.1515/ijb-2016-0057 (2017)
fastMitoCalc: an ultra-fast program to estimate mitochondrial DNA copy number from whole-genome sequences Qian, Y; Butler, TJ; Opsahl-Ong, K et al. Bioinformatics, DOI://10.1093/bioinformatics/btw835 (2017)
The isomeric preference of an atypical dopamine transporter inhibitor contributes to its selection of the transporter conformation Abramyan, AM; Stolzenberg, S; Li, Z; Loland, CJ; Noé, F; Shi, L; ACS Chem Neurosci, DOI://10.1021/acschemneuro.7b00094 (2017)
Behavioral and Neural Sustained Attention Deficits in Disruptive Mood Dysregulation Disorder and Attention-Deficit/Hyperactivity Disorder Pagliaccio, D; Wiggins, JL; Adleman, NE et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2017.02.008 (2017)
Synthesis of Dopamine in E.coli Using Plasmid Based Expression System and Its Marked Effect on Host Growth Profiles Das, A; Verma, A; Mukherjee, KJ; Prep. Biochem. Biotechnol., DOI://10.1080/10826068.2017.1320291 (2017)
Immunocompetent mouse allograft models for development of therapies to target breast cancer metastasis Yang, Y; Yang, HH; Hu, Y et al. Oncotarget, DOI://10.18632/oncotarget.15695 (2017)
Transposable elements in the Anopheles funestus transcriptome Fernández-Medina, RD; Carareto, CMA; Struchiner, CJ; Ribeiro, JMC; Genetica, DOI://10.1007/s10709-017-9964-z (2017)
fMRI clustering and false-positive rates Cox, RW; Chen, G; Glen, DR; Reynolds, RC; Taylor, PA; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1614961114 (2017)
Sequence and Structural Analyses Reveal Distinct and Highly Diverse Human CD8(+) TCR Repertoires to Immunodominant Viral Antigens Chen, G; Yang, X; Ko, A et al. Cell Rep, DOI://10.1016/j.celrep.2017.03.072 (2017)
Power Grid Protection of the Muscle Mitochondrial Reticulum Glancy, B; Hartnell, LM; Combs, CA et al. Cell Rep, DOI://10.1016/j.celrep.2017.03.063 (2017)

Brain-derived neurotrophic factor Val(66)Met genotype and ovarian steroids interactively modulate working memory-related hippocampal function in women: a multimodal neuroimaging study Wei, SM; Baller, EB; Kohn, PD et al. Mol. Psychiatry, DOI://10.1038/mp.2017.72 (2017)
The Molecular Revolution in Cutaneous Biology: Investigating the Skin Microbiome Kong, HH; Segre, JA; J. Invest. Dermatol., DOI://10.1016/j.jid.2016.07.045 (2017)
Brownian Ratchet Mechanism for Faithful Segregation of Low-Copy-Number Plasmids Hu, L; Vecchiarelli, AG; Mizuuchi, K; Neuman, KC; Liu, J; Biophys. J., DOI://10.1016/j.bpj.2017.02.039 (2017)
H3K4 demethylase KDM5B regulates global dynamics of transcription elongation and alternative splicing in embryonic stem cells He, R; Kidder, BL; Nucleic Acids Res., DOI://10.1093/nar/gkx251 (2017)
Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly Schneider, VA; Graves-Lindsay, T; Howe, K et al. Genome Res., DOI://10.1101/gr.213611.116 (2017)
FMRI Clustering in AFNI: False-Positive Rates Redux Cox, RW; Chen, G; Glen, DR; Reynolds, RC; Taylor, PA; Brain Connect, DOI://10.1089/brain.2016.0475 (2017)

A novel perivascular cell population in the zebrafish brain Venero Galanternik, M; Castranova, D; Gore, AV et al. Elife, DOI://10.7554/eLife.24369 (2017)
Intrinsic Functional Connectivity of the Central Nucleus of the Amygdala and Bed Nucleus of the Stria Terminalis Gorka, AX; Torrisi, S; Shackman, AJ; Grillon, C; Ernst, M; Neuroimage, DOI://10.1016/j.neuroimage.2017.03.007 (2017)
Hydrophobic-Hydrophilic Forces in Protein Folding Durell, SR; Ben-Naim, A; Biopolymers, DOI://10.1002/bip.23020 (2017)
Detection of genetic loci associated with plasma fetuin-A: A meta-analysis of genome-wide association studies from the CHARGE Consortium Jensen, MK; Jensen, RA; Mukamal, KJ et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddx091 (2017)
Molecular convergence in ex vivo models of Diamond-Blackfan anemia O'Brien, KA; Farrar, JE; Vlachos, A et al. Blood, DOI://10.1182/blood-2017-01-760462 (2017)
A New Natural Product Analog of Blasticidin S Reveals Cellular Uptake Facilitated by the NorA Multidrug Transporter Davison, JR; Lohith, KM; Wang, X et al. Antimicrob. Agents Chemother., DOI://10.1128/AAC.02635-16 (2017)
A big data approach to the development of mixed-effects models for seizure count data Tharayil, JJ; Chiang, S; Moss, R; Stern, JM; Theodore, WH; Goldenholz, DM; Epilepsia, DOI://10.1111/epi.13727 (2017)
Retrospective correction of frequency drift in spectral editing: The GABA editing example van der Veen, JW; Marenco, S; Berman, KF; Shen, J; NMR Biomed, DOI://10.1002/nbm.3725 (2017)
Engineering efficient production of itaconic acid from diverse substrates in Escherichia coli Chang, P; Chen, GS; Chu, HY; Lu, KW; Shen, CR; J. Biotechnol., DOI://10.1016/j.jbiotec.2017.03.026 (2017)
REEP6 mediates trafficking of a subset of Clathrin-coated vesicles and is critical for rod photoreceptor function and survival Veleri, S; Nellissery, J; Mishra, B et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddx111 (2017)
Stable functional networks exhibit consistent timing in the human brain Chapeton, JI; Inati, SK; Zaghloul, KA; Brain, DOI://10.1093/brain/aww337 (2017)
Multi-echo fMRI: A review of applications in fMRI denoising and analysis of BOLD signals Kundu, P; Voon, V; Balchandani, P; Lombardo, MV; Poser, BA; Bandettini, PA; Neuroimage, DOI://10.1016/j.neuroimage.2017.03.033 (2017)
Characterization of four arginine kinases in the ciliate Paramecium tetraurelia: Investigation on the substrate inhibition mechanism Yano, D; Suzuki, T; Hirokawa, S; Fuke, K; Suzuki, T; Int. J. Biol. Macromol., DOI://10.1016/j.ijbiomac.2017.03.133 (2017)
An investigation of doubt in obsessive-compulsive disorder Samuels, J; Bienvenu, OJ; Krasnow, J et al. Compr Psychiatry, DOI://10.1016/j.comppsych.2017.03.004 (2017)
Gramicidin A Channel Formation Induces Local Lipid Redistribution II: A 3D Continuum Elastic Model Sodt, AJ; Beaven, AH; Andersen, OS; Im, W; Pastor, RW; Biophys. J., DOI://10.1016/j.bpj.2017.01.035 (2017)
APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast Saini, N; Roberts, SA; Sterling, JF; Malc, EP; Mieczkowski, PA; Gordenin, DA; DNA Repair (Amst.), DOI://10.1016/j.dnarep.2017.03.003 (2017)
Automatic MR prostate segmentation by deep learning with holistically-nested networks Ruida Cheng ; Holger R. Roth ; Nathan Lay ; Le Lu ; Baris Turkbey ; William Gandler ; Evan S. McCreedy ; Peter Choyke ; Ronald M. Summers ; Matthew J. McAuliffe Proc. SPIE 10133, Medical Imaging 2017, doi:10.1117/12.2254558 (2017)
Common and rare exonic MUC5B variants associated with type 2 diabetes in Han Chinese Chen, G; Zhang, Z; Adebamowo, SN et al. PLoS ONE, DOI://10.1371/journal.pone.0173784 (2017)

Macrophilone A: Structure Elucidation, Total Synthesis, and Functional Evaluation of a Biologically Active Iminoquinone from the Marine Hydroid Macrorhynchia philippina Zlotkowski, K; Hewitt, WM; Yan, P et al. Org. Lett., DOI://10.1021/acs.orglett.7b00496 (2017)
Expressed Structurally-stable Inverted Duplicates in Mammalian Genomes as Functional Noncoding Elements Chen, ZX; Oliver, B; Zhang, YE; Gao, G; Long, M; Genome Biol Evol, DOI://10.1093/gbe/evx054 (2017)
Korean Pediatric and Adult Head Computational Phantoms and Application to Photon Specific Absorbed Fractions Calculations Villoing, D; McMillan, D; Kim, KP et al. Radiat Prot Dosimetry, DOI://10.1093/rpd/ncx009 (2017)
Functional assessment of CTCF sites at cytokine-sensing mammary enhancers using CRISPR/Cas9 gene editing in mice Lee, HK; Willi, M; Wang, C et al. Nucleic Acids Res., DOI://10.1093/nar/gkx185 (2017)
Flexible CRISPR library construction using parallel oligonucleotide retrieval Read, A; Gao, S; Batchelor, E; Luo, J; Nucleic Acids Res., DOI://10.1093/nar/gkx181 (2017)
Determining Cysteines Available for Covalent Inhibition Across the Human Kinome Zhao, Z; Liu, Q; Bliven, S; Xie, L; Bourne, PE; J. Med. Chem., DOI://10.1021/acs.jmedchem.6b01815 (2017)

DNase-active TREX1 frame-shift mutants induce serologic autoimmunity in mice Sakai, T; Miyazaki, T; Shin, DM et al. J. Autoimmun., DOI://10.1016/j.jaut.2017.03.001 (2017)
The Role of TM5 in Na2 Release and the Conformational Transition of Neurotransmitter:Sodium Symporters toward the Inward-Open State Stolzenberg, S; Li, Z; Quick, M et al. J. Biol. Chem., DOI://10.1074/jbc.M116.757153 (2017)
Whole-Exome Sequencing for Diagnosis of Turner Syndrome: Toward Next-Generation Sequencing and Newborn Screening Murdock, DR; Donovan, FX; Chandrasekharappa, SC et al. J. Clin. Endocrinol. Metab., DOI://10.1210/jc.2016-3414 (2017)
Neuroanatomic, epigenetic and genetic differences in monozygotic twins discordant for attention deficit hyperactivity disorder Chen, YC; Sudre, G; Sharp, W et al. Mol. Psychiatry, DOI://10.1038/mp.2017.45 (2017)
Predicting drug-drug interactions through drug structural similarities and interaction networks incorporating pharmacokinetics and pharmacodynamics knowledge Takeda, T; Hao, M; Cheng, T; Bryant, SH; Wang, Y; J Cheminform, DOI://10.1186/s13321-017-0200-8 (2017)
Modulation of opioid receptor affinity and efficacy via N-substitution of 9β-hydroxy-5-(3-hydroxyphenyl)morphan: Synthesis and computer simulation study Truong, PM; Hassan, SA; Lee, YS et al. Bioorg. Med. Chem., DOI://10.1016/j.bmc.2017.02.064 (2017)

Computational Study of the Forces Driving Aggregation of Ultrasmall Nanoparticles in Biological Fluids Hassan, SA ACS Nano, DOI://10.1021/acsnano.7b00981 (2017)
Whole exome sequencing in the Framingham Heart Study identifies rare variation in HYAL2 that influences platelet aggregation Eicher, JD; Chen, MH; Pitsillides, AN et al. Thromb. Haemost., DOI://10.1160/TH16-09-0677 (2017)
Identification of β-Catenin-Interacting Proteins in Nuclear Fractions of Native Rat Collecting Duct Cells Hwang, JR; Chou, CL; Medvar, B; Knepper, MA; Jung, HJ; Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00054.2017 (2017)
Canu: scalable and accurate long-read assembly via adaptive k-mer weighting and repeat separation Koren, S; Walenz, BP; Berlin, K; Miller, JR; Bergman, NH; Phillippy, AM; Genome Res., DOI://10.1101/gr.215087.116 (2017)
BTBD18 Regulates a Subset of piRNA-Generating Loci through Transcription Elongation in Mice Zhou, L; Canagarajah, B; Zhao, Y et al. Dev. Cell, DOI://10.1016/j.devcel.2017.02.007 (2017)
A large outbreak of acute gastroenteritis in Shippensburg, Pennsylvania, 1972 revisited: evidence for common source exposure to a recombinant GII.Pg/GII.3 norovirus Johnson, JA; Parra, GI; Levenson, EA; Green, KY; Epidemiol. Infect., DOI://10.1017/S0950268817000498 (2017)

Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits Yao, C; Joehanes, R; Johnson, AD et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2017.02.003 (2017)
Effect of Detergent Micelle Environment on P-glycoprotein (ABCB1)-Ligand Interactions Shukla, S; Abel, B; Chufan, EE; Ambudkar, SV; J. Biol. Chem., DOI://10.1074/jbc.M116.771634 (2017)
Single-molecule sequencing and chromatin conformation capture enable de novo reference assembly of the domestic goat genome Bickhart, DM; Rosen, BD; Koren, S et al. Nat. Genet., DOI://10.1038/ng.3802 (2017)
Analysis of large versus small dogs reveals three genes on the canine X chromosome associated with body weight, muscling and back fat thickness Plassais, J; Rimbault, M; Williams, FJ; Davis, BW; Schoenebeck, JJ; Ostrander, EA; PLoS Genet., DOI://10.1371/journal.pgen.1006661 (2017)
SMYD5 regulates H4K20me3-marked heterochromatin to safeguard ES cell self-renewal and prevent spurious differentiation Kidder, BL; Hu, G; Cui, K; Zhao, K; Epigenetics Chromatin, DOI://10.1186/s13072-017-0115-7 (2017)
Genome-wide siRNA screen of genes regulating the LPS-induced NF-κB and TNF-α responses in mouse macrophages Li, N; Katz, S; Dutta, B; Benet, ZL; Sun, J; Fraser, ID; Sci Data, DOI://10.1038/sdata.2017.8 (2017)
Genome-wide siRNA screen of genes regulating the LPS-induced TNF-α response in human macrophages Sun, J; Katz, S; Dutta, B; Wang, Z; Fraser, ID; Sci Data, DOI://10.1038/sdata.2017.7 (2017)
FMRI Clustering in AFNI: False Positive Rates Redux Robert W. Cox, Gang Chen, Daniel R. Glen, Richard C. Reynolds, Paul A. Taylor Brain Connectivity, DOI: 10.1089/brain.2016.047 (2017)
Permanganate/S1 Nuclease Footprinting Reveals Non-B DNA Structures with Regulatory Potential across a Mammalian Genome Kouzine, F; Wojtowicz, D; Baranello, L et al. Cell Syst, DOI://10.1016/j.cels.2017.01.013 (2017)
Circulating tumor cells capture disease evolution in advanced prostate cancer Lack, J; Gillard, M; Cam, M; Paner, GP; VanderWeele, DJ; J Transl Med, DOI://10.1186/s12967-017-1138-3 (2017)
The effects of shared information on semantic calculations in the gene ontology Bible, PW; Sun, HW; Morasso, MI; Loganantharaj, R; Wei, L; Comput Struct Biotechnol J, DOI://10.1016/j.csbj.2017.01.009 (2017)
Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer Liu, Q; Acharya, P; Dolan, MA et al. Nat. Struct. Mol. Biol., DOI://10.1038/nsmb.3382 (2017)

Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies Hedman, ÅK; Mendelson, MM; Marioni, RE et al. Circ Cardiovasc Genet, DOI://10.1161/CIRCGENETICS.116.001487 (2017)
Ultra-High-Field fMRI Reveals a Role for the Subiculum in Scene Perceptual Discrimination Hodgetts, CJ; Voets, NL; Thomas, AG; Clare, S; Lawrence, AD; Graham, KS; J. Neurosci., DOI://10.1523/JNEUROSCI.3225-16.2017 (2017)
Circulating miRNA Associated with Posttraumatic Stress Disorder in a Cohort of Military Combat Veterans Christiana G. Martin, Hyungsuk Kim, Sijung Yun, Whitney Livingston, Joseph Fetta, Vincent Mysliwiec, Tristin Baxter, Jessica M. Gill Psychiatry Research, doi://10.1016/j.psychres.2017.01.081 (2017)
The dynamic mechanism of RASSF5 and MST kinase activation by Ras Liao, TJ; Jang, H; Tsai, CJ; Fushman, D; Nussinov, R; Phys Chem Chem Phys, DOI://10.1039/c6cp08596b (2017)
Genome-Wide Identification of Basic Helix-Loop-Helix and NF-1 Motifs Underlying GR Binding Sites in Male Rat Hippocampus Pooley, JR; Flynn, BP; Grøntved, L et al. Endocrinology, DOI://10.1210/en.2016-1929 (2017)
Multivariate meta-analysis with an increasing number of parameters Boca, SM; Pfeiffer, RM; Sampson, JN; Biom J, DOI://10.1002/bimj.201600013 (2017)
Anopheline salivary protein genes and gene families: an evolutionary overview after the whole genome sequence of sixteen Anopheles species Arcà, B; Lombardo, F; Struchiner, CJ; Ribeiro, JM; BMC Genomics, DOI://10.1186/s12864-017-3579-8 (2017)
Somatic mutations in murine models of leukemia and lymphoma: Disease specificity and clinical relevance Goldberg, L; Gough, SM; Lee, F et al. Genes Chromosomes Cancer, DOI://10.1002/gcc.22451 (2017)
Genetic regulatory signatures underlying islet gene expression and type 2 diabetes Varshney, A; Scott, LJ; Welch, RP et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1621192114 (2017)
A novel DLX3-PKC integrated signaling network drives keratinocyte differentiation Palazzo, E; Kellett, MD; Cataisson, C et al. Cell Death Differ., DOI://10.1038/cdd.2017.5 (2017)
Folding behavior of a T-shaped, ribosome-binding translation enhancer implicated in a wide-spread conformational switch Le, MT; Kasprzak, WK; Kim, T et al. Elife, DOI://10.7554/eLife.22883 (2017)
Messenger RNA and MicroRNA transcriptomic signatures of cardiometabolic risk factors McManus, DD; Rong, J; Huan, T et al. BMC Genomics, DOI://10.1186/s12864-017-3533-9 (2017)

Thiazole-valine peptidomimetic (TTT-28) antagonizes multidrug resistance in vitro and in vivo by selectively inhibiting the efflux activity of ABCB1 Wang, YJ; Patel, BA; Anreddy, N et al. Sci Rep, DOI://10.1038/srep42106 (2017)
iPSCs and fibroblast subclones from the same fibroblast population contain comparable levels of sequence variations Kwon, EM; Connelly, JP; Hansen, NF et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1616035114 (2017)
Insights from NMR Spectroscopy into the Conformational Properties of Man-9 and Its Recognition by Two HIV Binding Proteins Shahzad-Ul-Hussan, S; Sastry, M; Lemmin, T et al. Chembiochem, DOI://10.1002/cbic.201600665 (2017)
Dense genotyping of immune-related loci implicates host responses to microbial exposure in Behçet's disease susceptibility Takeuchi, M; Mizuki, N; Meguro, A et al. Nat. Genet., DOI://10.1038/ng.3786 (2017)
MNase-Sensitive Complexes in Yeast: Nucleosomes and Non-histone Barriers Chereji, RV; Ocampo, J; Clark, DJ; Mol. Cell, DOI://10.1016/j.molcel.2016.12.009 (2017)
Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing Jansen, IE; Ye, H; Heetveld, S et al. Genome Biol., DOI://10.1186/s13059-017-1147-9 (2017)

Amyloid β Ion Channels in a Membrane Comprising Brain Total Lipid Extracts Lee, J; Kim, YH; T Arce, F et al. ACS Chem Neurosci, DOI://10.1021/acschemneuro.7b00006 (2017)
Secretory Expression and Characterization of Chinese Narcissus GNA-Like Lectin in Pichia pastoris Li, X; Zhang, P; Zhang, N et al. Appl. Biochem. Biotechnol., DOI://10.1007/s12010-017-2408-5 (2017)
Hybrid assembly of the large and highly repetitive genome of Aegilops tauschii, a progenitor of bread wheat, with the MaSuRCA mega-reads algorithm Zimin, AV; Puiu, D; Luo, MC et al. Genome Res., DOI://10.1101/gr.213405.116 (2017)
Hedgehog Signaling Inhibitors Fail to Reduce Merkel Cell Carcinoma Viability Carroll, TM; Williams, JS; Daily, K et al. J. Invest. Dermatol., DOI://10.1016/j.jid.2017.01.008 (2017)
Differential methylation of genes in individuals exposed to maternal diabetes in utero Chen, P; Piaggi, P; Traurig, M et al. Diabetologia, DOI://10.1007/s00125-016-4203-1 (2017)
ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans Lyons, JJ; Liu, Y; Ma, CA et al. J. Exp. Med., DOI://10.1084/jem.20161435 (2017)

Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies Joehanes, R; Zhang, X; Huan, T et al. Genome Biol., DOI://10.1186/s13059-016-1142-6 (2017)
Frequent inactivating germline mutations in DNA repair genes in patients with Ewing sarcoma Brohl, AS; Patidar, R; Turner, CE et al. Genet. Med., DOI://10.1038/gim.2016.206 (2017)
Gleason Score 7 Prostate Cancers Emerge through Branched Evolution of Clonal Gleason Pattern 3 and 4 Sowalsky, AG; Kissick, HT; Gerrin, SJ et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-16-2414 (2017)
Dose coefficients for ICRP reference pediatric phantoms exposed to idealised external gamma fields Chang, LA; Simon, SL; Jorgensen, TJ; Schauer, DA; Lee, C; J Radiol Prot, DOI://10.1088/1361-6498/aa559e (2017)
Actin dynamics and competition for myosin monomer govern the sequential amplification of myosin filaments Beach, JR; Bruun, KS; Shao, L et al. Nat. Cell Biol., DOI://10.1038/ncb3463 (2017)
SDHD promoter mutations ablate GABP transcription factor binding in melanoma Zhang, T; Xu, M; Makowski, MM et al. Cancer Res., DOI://10.1158/0008-5472.CAN-16-0919 (2017)

Functionally-interdependent shape-switching nanoparticles with controllable properties Halman, JR; Satterwhite, E; Roark, B et al. Nucleic Acids Res., DOI://10.1093/nar/gkx008 (2017)
Static and Evolving Norovirus Genotypes: Implications for Epidemiology and Immunity Parra, GI; Squires, RB; Karangwa, CK et al. PLoS Pathog., DOI://10.1371/journal.ppat.1006136 (2017)
Novel genetic loci associated with hippocampal volume Hibar, DP; Adams, HH; Jahanshad, N et al. Nat Commun, DOI://10.1038/ncomms13624 (2017)
Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach Mendelson, MM; Marioni, RE; Joehanes, R et al. PLoS Med., DOI://10.1371/journal.pmed.1002215 (2017)
Quantitative stability of hematopoietic stem and progenitor cell clonal output in rhesus macaques receiving transplants Koelle, SJ; Espinoza, DA; Wu, C et al. Blood, DOI://10.1182/blood-2016-07-728691 (2017)
Designer Drugs 2.0 Huestis, MA; Tyndale, RF; Clin. Pharmacol. Ther., DOI://10.1002/cpt.575 (2017)
Sequence of Reston Virus Isolate AZ-1435, an Ebolavirus Isolate Obtained during the 1989-1990 Reston Virus Epizootic in the United States Cornish, JP; Diaz, L; Ricklefs, SM et al. Genome Announc, DOI://10.1128/genomeA.01448-16 (2017)
An Estimation of Hybrid Quantum Mechanical Molecular Mechanical Polarization Energies for Small Molecules Using Polarizable Force-Field Approaches Huang, J; Mei, Y; König, G et al. J Chem Theory Comput, DOI://10.1021/acs.jctc.6b01125 (2017)
Familial Mutations May Switch Conformational Preferences in α-Synuclein Fibrils Xu, L; Ma, B; Nussinov, R; Thompson, D; ACS Chem Neurosci, DOI://10.1021/acschemneuro.6b00406 (2017)
High fat diet-induced changes of mouse hepatic transcription and enhancer activity can be reversed by subsequent weight loss Siersbæk, M; Varticovski, L; Yang, S et al. Sci Rep, DOI://10.1038/srep40220 (2017)
The primacy of NF1 loss as the driver of tumorigenesis in neurofibromatosis type 1-associated plexiform neurofibromas Pemov, A; Li, H; Patidar, R et al. Oncogene, DOI://10.1038/onc.2016.464 (2017)
Performing Skin Microbiome Research: A Method to the Madness Kong, HH; Andersson, B; Clavel, T et al. J. Invest. Dermatol., DOI://10.1016/j.jid.2016.10.033 (2017)

Characterization of the disassembly and reassembly of the HBV glycoprotein surface antigen, a pliable nanoparticle vaccine platform Gallagher, JR; Torian, U; McCraw, DM; Harris, AK; Virology, DOI://10.1016/j.virol.2016.12.025 (2017)
The Papillomavirus Episteme: a major update to the papillomavirus sequence database Van Doorslaer, K; Li, Z; Xirasagar, S et al. Nucleic Acids Res., DOI://10.1093/nar/gkw879 (2017)
Genetic stability of genome-scale deoptimized RNA virus vaccine candidates under selective pressure Le Nouën, C; McCarty, T; Brown, M et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1619242114 (2017)
Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting Doria-Rose, NA; Altae-Tran, HR; Roark, RS et al. PLoS Pathog., DOI://10.1371/journal.ppat.1006148 (2017)
An insight into the sialome of Hyalomma excavatum Ribeiro, JM; Slovák, M; Francischetti, IM; Ticks Tick Borne Dis, DOI://10.1016/j.ttbdis.2016.08.011 (2017)
Data integration in physiology using Bayes' rule and minimum Bayes' factors: deubiquitylating enzymes in the renal collecting duct Xue, Z; Chen, JX; Zhao, Y; Medvar, B; Knepper, MA; Physiol. Genomics, DOI://10.1152/physiolgenomics.00120.2016 (2017)

Human Neuronal Calcium Sensor-1 Protein Avoids Histidine Residues To Decrease pH Sensitivity Gong, Y; Zhu, Y; Zou, Y; Ma, B; Nussinov, R; Zhang, Q; J Phys Chem B, DOI://10.1021/acs.jpcb.6b11094 (2017)
Structural studies of influenza virus RNPs by electron microscopy indicate molecular contortions within NP supra-structures Gallagher, JR; Torian, U; McCraw, DM; Harris, AK; J. Struct. Biol., DOI://10.1016/j.jsb.2016.12.007 (2017)
Computational models of the neural control of breathing Molkov, YI; Rubin, JE; Rybak, IA; Smith, JC; Wiley Interdiscip Rev Syst Biol Med, DOI://10.1002/wsbm.1371 (2017)
EBI2 overexpression in mice leads to B1 B-cell expansion and chronic lymphocytic leukemia-like B-cell malignancies Niss Arfelt, K; Barington, L; Benned-Jensen, T et al. Blood, DOI://10.1182/blood-2016-02-697185 (2017)
The cell cycle restricts activation-induced cytidine deaminase activity to early G1 Wang, Q; Kieffer-Kwon, KR; Oliveira, TY et al. J. Exp. Med., DOI://10.1084/jem.20161649 (2017)
The bald and the beautiful: hairlessness in domestic dog breeds Parker, HG; Harris, A; Dreger, DL; Davis, BW; Ostrander, EA; Philos. Trans. R. Soc. Lond., B, Biol. Sci., DOI://10.1098/rstb.2015.0488 (2017)

Neural Markers in Pediatric Bipolar Disorder and Familial Risk for Bipolar Disorder Wiggins, JL; Brotman, MA; Adleman, NE et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2016.10.009 (2017)
ADORA1 mutations are not a common cause of Parkinson's disease and dementia with Lewy bodies Blauwendraat, C; Nalls, MA; Federoff, M et al. Mov. Disord., DOI://10.1002/mds.26886 (2017)
Temporal association of ORCA/LRWD1 to late-firing origins during G1 dictates heterochromatin replication and organization Wang, Y; Khan, A; Marks, AB et al. Nucleic Acids Res., DOI://10.1093/nar/gkw1211 (2017)
Acquired somatic mutations in PNH reveal long-term maintenance of adaptive NK cells independent of HSPCs Corat, MA; Schlums, H; Wu, C et al. Blood, DOI://10.1182/blood-2016-08-734285 (2017)
Whole exome sequencing in 75 high-risk families with validation and replication in independent case-control studies identifies TANGO2, OR5H14, and CHAD as new prostate cancer susceptibility genes Karyadi, DM; Geybels, MS; Karlins, E et al. Oncotarget, DOI://10.18632/oncotarget.13646 (2017)
Long-term monitoring of cardiorespiratory patterns in drug-resistant epilepsy Goldenholz, DM; Kuhn, A; Austermuehle, A et al. Epilepsia, DOI://10.1111/epi.13606 (2017)
Assessing variation across 8 established East Asian loci for type 2 diabetes mellitus in American Indians: Suggestive evidence for new sex-specific diabetes signals in GLIS3 and ZFAND3 Muller, YL; Piaggi, P; Chen, P et al. Diabetes Metab. Res. Rev., DOI://10.1002/dmrr.2869 (2017)
Estimating the Heritability of Structural and Functional Brain Connectivity in Families Affected by Attention-Deficit/Hyperactivity Disorder Sudre, G; Choudhuri, S; Szekely, E et al. JAMA Psychiatry, DOI://10.1001/jamapsychiatry.2016.3072 (2017)
Oculocutaneous albinism type 1: link between mutations, tyrosinase conformational stability, and enzymatic activity Dolinska, MB; Kus, NJ; Farney, SK; Wingfield, PT; Brooks, BP; Sergeev, YV; Pigment Cell Melanoma Res, DOI://10.1111/pcmr.12546 (2017)
DLX3-Dependent Regulation of Ion Transporters and Carbonic Anhydrases is Crucial for Enamel Mineralization Duverger, O; Ohara, T; Bible, PW; Zah, A; Morasso, MI; J. Bone Miner. Res., DOI://10.1002/jbmr.3022 (2017)
Untangling the relatedness among correlations, Part II: Inter-subject correlation group analysis through linear mixed-effects modeling Chen, G; Taylor, PA; Shin, YW; Reynolds, RC; Cox, RW; Neuroimage, DOI://10.1016/j.neuroimage.2016.08.029 (2017)
Topographical and physiological differences of the skin mycobiome in health and disease Jo, JH; Kennedy, EA; Kong, HH; Virulence, DOI://10.1080/21505594.2016.1249093 (2017)
Empirically derived patterns of psychiatric symptoms in youth: A latent profile analysis Kircanski, K; Zhang, S; Stringaris, A et al. J Affect Disord, DOI://10.1016/j.jad.2016.09.016 (2017)
Absolute binding free energy calculations of CBClip host-guest systems in the SAMPL5 blind challenge Lee, J; Tofoleanu, F; Pickard, FC et al. J. Comput. Aided Mol. Des., DOI://10.1007/s10822-016-9968-2 (2017)
Immobilized MutS-Mediated Error Removal of Microchip-Synthesized DNA Wan, W; Wang, D; Gao, X; Hong, J; Methods Mol. Biol., DOI://10.1007/978-1-4939-6343-0_17 (2017)
Perfluoroalkyl Chemicals, Menstrual Cycle Length, and Fecundity: Findings from a Prospective Pregnancy Study Lum, KJ; Sundaram, R; Barr, DB; Louis, TA; Buck Louis, GM; Epidemiology, DOI://10.1097/EDE.0000000000000552 (2017)
Anxiety Patients Show Reduced Working Memory Related dlPFC Activation During Safety and Threat Balderston, NL; Vytal, KE; O'Connell, K et al. Depress Anxiety, DOI://10.1002/da.22518 (2017)

2016 (412 papers)

Direct Regulation of Alternative Splicing by SMAD3 through PCBP1 Is Essential to the Tumor-Promoting Role of TGF-β Tripathi, V; Sixt, KM; Gao, S et al. Mol. Cell, DOI://10.1016/j.molcel.2016.09.013 (2016)

Functional connectivity during masked and unmasked face emotion processing in bipolar disorder Tseng, WL; Thomas, LA; Harkins, E et al. Psychiatry Res Neuroimaging, DOI://10.1016/j.pscychresns.2016.10.006 (2016)
Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase Puppala, AK; French, RL; Matthies, D; Baxa, U; Subramaniam, S; Simonović, M; Sci Rep, DOI://10.1038/srep32563 (2016)
Ionic immune suppression within the tumour microenvironment limits T cell effector function Eil, R; Vodnala, SK; Clever, D et al. Nature, DOI://10.1038/nature19364 (2016)
The transcription factor BACH2 promotes tumor immunosuppression Roychoudhuri, R; Eil, RL; Clever, D et al. J. Clin. Invest., DOI://10.1172/JCI82884 (2016)
BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers Roychoudhuri, R; Clever, D; Li, P et al. Nat. Immunol., DOI://10.1038/ni.3441 (2016)
Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche Clever, D; Roychoudhuri, R; Constantinides, MG et al. Cell, DOI://10.1016/j.cell.2016.07.032 (2016)

Memory T cell-driven differentiation of naive cells impairs adoptive immunotherapy Klebanoff, CA; Scott, CD; Leonardi, AJ et al. J. Clin. Invest., DOI://10.1172/JCI81217 (2016)
Drugging Ras GTPase: a comprehensive mechanistic and signaling structural view Lu, S; Jang, H; Gu, S; Zhang, J; Nussinov, R; Chem Soc Rev, DOI://10.1039/c5cs00911a (2016)
Human-Mouse Chimeras with Normal Expression and Function Reveal That Major Domain Swapping Is Tolerated by P-Glycoprotein (ABCB1) Pluchino, KM; Hall, MD; Moen, JK et al. Biochemistry, DOI://10.1021/acs.biochem.5b01064 (2016)
Pioneer factors and ATP-dependent chromatin remodeling factors interact dynamically: A new perspective: Multiple transcription factors can effect chromatin pioneer functions through dynamic interactions with ATP-dependent chromatin remodeling factors Swinstead, EE; Paakinaho, V; Presman, DM; Hager, GL; Bioessays, DOI://10.1002/bies.201600137 (2016)
Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant Li, J; Woods, SL; Healey, S et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2016.03.001 (2016)
Deep genome sequencing and variation analysis of 13 inbred mouse strains defines candidate phenotypic alleles, private variation and homozygous truncating mutations Doran, AG; Wong, K; Flint, J; Adams, DJ; Hunter, KW; Keane, TM; Genome Biol., DOI://10.1186/s13059-016-1024-y (2016)
A Small Number of Residues Can Determine if Linker Histones Are Bound On or Off Dyad in the Chromatosome Zhou, BR; Feng, H; Ghirlando, R; Li, S; Schwieters, CD; Bai, Y; J. Mol. Biol., DOI://10.1016/j.jmb.2016.08.016 (2016)
Comparing Brain Morphometry Across Multiple Childhood Psychiatric Disorders Gold, AL; Brotman, MA; Adleman, NE et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2016.08.008 (2016)
Toward elucidating the heat activation mechanism of the TRPV1 channel gating by molecular dynamics simulation Wen, H; Qin, F; Zheng, W; Proteins, DOI://10.1002/prot.25177 (2016)
Identification of therapeutic targets applicable to clinical strategies in ovarian cancer Kim, MK; Caplen, N; Chakka, S et al. BMC Cancer, DOI://10.1186/s12885-016-2675-5 (2016)
Blind prediction of distribution in the SAMPL5 challenge with QM based protomer and pK a corrections Pickard, FC; König, G; Tofoleanu, F et al. J. Comput. Aided Mol. Des., DOI://10.1007/s10822-016-9955-7 (2016)
Childhood peer network characteristics: genetic influences and links with early mental health trajectories Szekely, E; Pappa, I; Wilson, JD et al. J Child Psychol Psychiatry, DOI://10.1111/jcpp.12493 (2016)

Outcome of the First wwPDB/CCDC/D3R Ligand Validation Workshop Adams, PD; Aertgeerts, K; Bauer, C et al. Structure, DOI://10.1016/j.str.2016.02.017 (2016)
Partition coefficients for the SAMPL5 challenge using transfer free energies Jones, MR; Brooks, BR; Wilson, AK; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-016-9964-6 (2016)
Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III Esser, L; Zhou, F; Zhou, Y et al. J. Biol. Chem., DOI://10.1074/jbc.M116.744391 (2016)
An Open Pilot Study of Training Hostile Interpretation Bias to Treat Disruptive Mood Dysregulation Disorder Stoddard, J; Sharif-Askary, B; Harkins, EA et al. J Child Adolesc Psychopharmacol, DOI://10.1089/cap.2015.0100 (2016)
Estimation of FST and the Impact of de novo Mutation Shriner, D; Chen, G; Adeyemo, A; Rotimi, CN; Hum. Hered., DOI://10.1159/000477782 (2016)
Neuroendocrine Tumor of the Pancreas as a Manifestation of Cowden Syndrome: A Case Report Neychev, V; Sadowski, SM; Zhu, J et al. J. Clin. Endocrinol. Metab., DOI://10.1210/jc.2015-3684 (2016)
Robust spike sorting of retinal ganglion cells tuned to spot stimuli Ghahari, A; Badea, TC; Conf Proc IEEE Eng Med Biol Soc, DOI://10.1109/EMBC.2016.7591054 (2016)
Assessing the reproducibility of exome copy number variations predictions Hong, CS; Singh, LN; Mullikin, JC; Biesecker, LG; Genome Med, DOI://10.1186/s13073-016-0336-6 (2016)
Whole Genome Sequencing of Newly Established Pancreatic Cancer Lines Identifies Novel Somatic Mutation (c.2587G>A) in Axon Guidance Receptor Plexin A1 as Enhancer of Proliferation and Invasion Sorber, R; Teper, Y; Abisoye-Ogunniyan, A et al. PLoS ONE, DOI://10.1371/journal.pone.0149833 (2016)
Computation of Hydration Free Energies Using the Multiple Environment Single System Quantum Mechanical/Molecular Mechanical Method König, G; Mei, Y; Pickard, FC et al. J Chem Theory Comput, DOI://10.1021/acs.jctc.5b00874 (2016)
Identifying Host Genetic Variants Associated with Microbiome Composition by Testing Multiple Beta Diversity Matrices Hua, X; Goedert, JJ; Landi, MT; Shi, J; Hum. Hered., DOI://10.1159/000448733 (2016)
Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data Shi, J; Park, JH; Duan, J et al. PLoS Genet., DOI://10.1371/journal.pgen.1006493 (2016)
Lineage-Specific and Non-specific Cytokine-Sensing Genes Respond Differentially to the Master Regulator STAT5 Zeng, X; Willi, M; Shin, HY; Hennighausen, L; Wang, C; Cell Rep, DOI://10.1016/j.celrep.2016.11.079 (2016)
Block network mapping approach to quantitative trait locus analysis Shreif, ZZ; Gatti, DM; Periwal, V; BMC Bioinformatics, DOI://10.1186/s12859-016-1351-8 (2016)
Meta-analysis of quantitative pleiotropic traits for next-generation sequencing with multivariate functional linear models Chiu, CY; Jung, J; Chen, W et al. Eur. J. Hum. Genet., DOI://10.1038/ejhg.2016.170 (2016)
Towards understanding the structural basis of partial agonism at the dopamine D3 receptor Michino, M; Boateng, CA; Donthamsetti, P et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.6b01148 (2016)
Comparison of parametric and machine methods for variable selection in simulated Genetic Analysis Workshop 19 data Holzinger, ER; Szymczak, S; Malley, J et al. BMC Proc, DOI://10.1186/s12919-016-0021-1 (2016)
From 20th Century Metabolic Wall Charts to 21st Century Systems Biology: Database of Mammalian Metabolic Enzymes Corcoran, CC; Grady, CR; Pisitkun, T; Parulekar, J; Knepper, MA; Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00601.2016 (2016)

Lipid and Peptide Diffusion in Bilayers: The Saffman-Delbrück Model and Periodic Boundary Conditions Venable, RM; Ingólfsson, HI; Lerner, MG et al. J Phys Chem B, DOI://10.1021/acs.jpcb.6b09111 (2016)
DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases Ligthart, S; Marzi, C; Aslibekyan, S et al. Genome Biol., DOI://10.1186/s13059-016-1119-5 (2016)
Structure-Based Scaffold Repurposing for G Protein-Coupled Receptors: Transformation of Adenosine Derivatives into 5HT2B/5HT2C Serotonin Receptor Antagonists Tosh, DK; Ciancetta, A; Warnick, E; Crane, S; Gao, ZG; Jacobson, KA; J. Med. Chem., DOI://10.1021/acs.jmedchem.6b01183 (2016)
Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications Ombrello, MJ; Arthur, VL; Remmers, EF et al. Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2016-210324 (2016)
Mechanisms of Evolution in High-Consequence Drug Resistance Plasmids He, S; Chandler, M; Varani, AM; Hickman, AB; Dekker, JP; Dyda, F; MBio, DOI://10.1128/mBio.01987-16 (2016)
Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study Shi, J; Hua, X; Zhu, B et al. PLoS Med., DOI://10.1371/journal.pmed.1002162 (2016)

Mapping Complex Traits in a Diversity Outbred F1 Mouse Population Identifies Germline Modifiers of Metastasis in Human Prostate Cancer Winter, JM; Gildea, DE; Andreas, JP et al. Cell Syst, DOI://10.1016/j.cels.2016.10.018 (2016)
Sparse multidimensional iterative lineshape-enhanced (SMILE) reconstruction of both non-uniformly sampled and conventional NMR data Ying, J; Delaglio, F; Torchia, DA; Bax, A; J. Biomol. NMR, DOI://10.1007/s10858-016-0072-7 (2016)
A comparison study of multivariate fixed models and Gene Association with Multiple Traits (GAMuT) for next-generation sequencing Chiu, CY; Jung, J; Wang, Y et al. Genet. Epidemiol., DOI://10.1002/gepi.22014 (2016)
Robust skull stripping using multiple MR image contrasts insensitive to pathology Roy, S; Butman, JA; Pham, DL; Neuroimage, DOI://10.1016/j.neuroimage.2016.11.017 (2016)
Association of Irritability and Anxiety With the Neural Mechanisms of Implicit Face Emotion Processing in Youths With Psychopathology Stoddard, J; Tseng, WL; Kim, P et al. JAMA Psychiatry, DOI://10.1001/jamapsychiatry.2016.3282 (2016)
Allosteric control of antibody-prion recognition through oxidation of a disulfide bond between the CH and CL chains Zhao, J; Nussinov, R; Ma, B; Protein Eng. Des. Sel., DOI://10.1093/protein/gzw065 (2016)
Early generated B1 B cells with restricted BCRs become chronic lymphocytic leukemia with continued c-Myc and low Bmf expression Hayakawa, K; Formica, AM; Brill-Dashoff, J et al. J. Exp. Med., DOI://10.1084/jem.20160712 (2016)
Molecular Diagnosis of Inherited Retinal Diseases in Indigenous African Populations by Whole-Exome Sequencing Roberts, L; Ratnapriya, R; du Plessis, M; Chaitankar, V; Ramesar, RS; Swaroop, A; Invest. Ophthalmol. Vis. Sci., DOI://10.1167/iovs.16-19785 (2016)
High-level expression of improved thermo-stable alkaline xylanase variant in Pichia Pastoris through codon optimization, multiple gene insertion and high-density fermentation Lu, Y; Fang, C; Wang, Q; Zhou, Y; Zhang, G; Ma, Y; Sci Rep, DOI://10.1038/srep37869 (2016)
Stage-Specific Transcriptome and Proteome Analyses of the Filarial Parasite Onchocerca volvulus and Its Wolbachia Endosymbiont Bennuru, S; Cotton, JA; Ribeiro, JM et al. MBio, DOI://10.1128/mBio.02028-16 (2016)
NRL-Regulated Transcriptome Dynamics of Developing Rod Photoreceptors Kim, JW; Yang, HJ; Brooks, MJ et al. Cell Rep, DOI://10.1016/j.celrep.2016.10.074 (2016)
Integrative network analysis reveals molecular mechanisms of blood pressure regulation Tianxiao Huan, Qingying Meng et al. Mol Syst Biol., doi: 10.15252/msb.20145399 (2016)

C. elegans DAF-2 as a Model for Human Insulin Receptoropathies David A. Bulger, Tetsunari Fukushige, Sijung Yun, Robert K. Semple, John A. Hanover, and Michael W. Krause Genes|Genomes|Genetics, doi:10.1534/g3.116.03718 (2016)
Generation and differentiation of induced pluripotent stem cells reveal ankylosing spondylitis risk gene expression in bone progenitors Gerlinde Layh-Schmitt, Shajia Lum Fatemehm Navid, Stephen R. Brooks, Emily Lazowick, Kathryn M. Davis, Cristina Montagna, Massimo Gadina, Robert A. Colbert Clinical Rheumatology, doi:10.1007/s10067-016-3469-5 (2016)
Whole-genome sequence, SNP chips and pedigree structure: building demographic profiles in domestic dog breeds to optimize genetic-trait mapping Dreger, DL; Rimbault, M; Davis, BW; Bhatnagar, A; Parker, HG; Ostrander, EA; Dis Model Mech, DOI://10.1242/dmm.027037 (2016)
Two Na+ Sites Control Conformational Change in a Neurotransmitter Transporter Homolog Sotiria Tavoulari, Eleonora Margheritis, Anu Nagarajan, David C. DeWitt, Yuan -Wei Zhang, Edwin Rosado, Silvia Ravera, Elizabeth Rhoades, Lucy R. Forrest and Gary Rudnick J Biol Chem. , doi: 10.1074/jbc.M115.692012. (2016)
Techniques for blood volume fMRI with VASO: From low-resolution mapping towards sub-millimeter layer-dependent applications Huber, L; Ivanov, D; Handwerker, DA et al. Neuroimage, DOI://10.1016/j.neuroimage.2016.11.039 (2016)
The genome of Onchocerca volvulus, agent of river blindness Cotton, JA; Bennuru, S; Grote, A et al. Nat Microbiol, DOI://10.1038/nmicrobiol.2016.216 (2016)

Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity Esser, L; Zhou, F; Pluchino, KM et al. J. Biol. Chem., DOI://10.1074/jbc.M116.755884 (2016)
Physiological basis of vascular autocalibration (VasA): Comparison to hypercapnia calibration methods Kazan, SM; Huber, L; Flandin, G; Ivanov, D; Bandettini, P; Weiskopf, N; Magn Reson Med, DOI://10.1002/mrm.26494 (2016)
Serine/Threonine Phosphatases and Aquaporin-2 Regulation in Renal Collecting Duct Sophia LeMaire, Viswanathan Raghuram, Cameron R. Grady, Christina M. Pickering, Chung-Lin Chou, Ezigbobiara N Umejiego, Mark A. Knepper Am. J. Physiol. - Renal Physiol. , DOI: 10.1152/ajprenal.00455.2016 (2016)
Identification of a novel lipid binding motif in apolipoprotein B by the analysis of hydrophobic cluster domains Scott M. Gordon, Mohsen Pourmousa, Maureen Sampson, Denis Sviridov, Rafique Islam, B. Scott Perrin Jr., Georgina Kemeh, Richard W. Pastor, Alan T. Remaley Biochimica et Biophysica Acta - Membranes, doi://10.1016/j.bbamem.2016.10.019 (2016)
Convergence and Sampling in Determining Free Energy Landscapes for Membrane Protein Association Jan Domanski, George Hedger, Robert B. Best, Phillip James Stansfeld, and Mark S. P. Sansom J. Phys. Chem. B, doi://10.1021/acs.jpcb.6b08445 (2016)
Transcriptome Profiling of NIH3T3 Cell Lines Expressing Opsin and the P23H Opsin Mutant Identifies Candidate Drugs for the Treatment of Retinitis Pigmentosa Yuanyuan Chen, Matthew J. Brooks, Linn Gieser, Anand Swaroop, Krzysztof Palczewski Pharmacological Research, doi://10.1016/j.phrs.2016.10.031 (2016)
RNA-seq analyses of the midgut from blood- and serum-fed Ixodes ricinus ticks Perner, J; Provazník, J; Schrenková, J; Urbanová, V; Ribeiro, JM; Kopáček, P; Sci Rep, DOI://10.1038/srep36695 (2016)
Transgenic mouse model of IgM(+) lymphoproliferative disease mimicking Waldenström macroglobulinemia Tompkins, VS; Sompallae, R; Rosean, TR et al. Blood Cancer J, DOI://10.1038/bcj.2016.95 (2016)
Mechanism of O2 diffusion and reduction in FeFe hydrogenases Adam Kubas, Christophe Orain et al. Nature Chemistry, doi:10.1038/nchem.2592 (2016)
Variance Decomposition for Single-Subject task-based fMRI activity estimates across many sessions Javier Gonzalez-Castillo, Gang Chen, Thomas E. Nichols, Peter A. Bandettini NeuroImage, doi://10.1016/j.neuroimage.2016.10.024 (2016)
Explicit Incorporation of Hard and Soft Protein-Protein Interactions Into Models for Crowding Effects in Binary and Ternary Protein Mixtures I. Comparison of Approximate Analytical Solutions With Numerical Simulation Travis Hoppe, and Allen P. Minton J. Phys. Chem. B, DOI: 10.1021/acs.jpcb.6b07736 (2016)
Resting State Connectivity of the Human Habenula at Ultra-High Field Salvatore Torrisi, Camilla L. Nord, Nicholas L. Balderston, Jonathan P. Roiser, Christian Grillon, Monique Ernst NeuroImage, 10.1016/j.neuroimage.2016.10.034 (2016)
The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts Saini, N; Roberts, SA; Klimczak, LJ et al. PLoS Genet., DOI://10.1371/journal.pgen.1006385 (2016)
Deriving frequency-dependent spatial patterns in MEG-derived resting state sensorimotor network: A novel multiband ICA technique Nugent, A. C., Luber, B., Carver, F. W., Robinson, S. E., Coppola, R. and Zarate, C. A. Hum. Brain Mapp., doi:10.1002/hbm.23417 (2016)
Additional Rare Variant Analysis in Parkinson's Disease Cases with and Without Known Pathogenic Mutations: Evidence for Oligogenic Inheritance Steven J. Lubbe, Valentina Escott-Price et al. Human Molecular Genetics, doi://10.1093/hmg/ddw348 (2016)
Longitudinal imaging in C9orf72 mutation carriers: Relationship to phenotype Mary Kay Floeter, Devin Bageac, Laura E. Danielian, Laura E. Braun, Bryan J. Traynor, , Justin Kwan NeuroImage: Clinical, doi://10.1016/j.nicl.2016.10.014 (2016)
Roles of H3K27me2 and H3K27me3 Examined during Fate Specification of Embryonic Stem Cells Juan, AH; Wang, S; Ko, KD et al. Cell Rep, DOI://10.1016/j.celrep.2016.09.087 (2016)
Light induced structural changes of the photoprotein mnemiopsin: Characterization and contribution in photoinactivation Pashandi, Z; Molakarimi, M; Sajedi, RH; Taghdir, M; Naderi-Manesh, H; J. Photochem. Photobiol. B, Biol., DOI://10.1016/j.jphotobiol.2016.10.018 (2016)
Racial differences in microRNA and gene expression in hypertensive women Dluzen, DF; Noren Hooten, N; Zhang, Y et al. Sci Rep, DOI://10.1038/srep35815 (2016)
Structural Characterization of Arginine Fingers: Identification of an Arginine Finger for the Pyrophosphatase dUTPases Gergely N Nagy, Reynier Suardiaz, Anna Lopata, Oliver Ozohanics, Karoly Vekey, Bernard R. Brooks, Ibolya Leveles, Judit Toth, Beata G Vertessy, and Edina Rost JACS, doi://10.1021/jacs.6b09012 (2016)
Molecular lock regulates binding of glycine to a primitive NMDA receptor Alvin Yu, Robert Alberstein, Alecia Thomas, Austin Zimmet, Richard Grey, Mark L. Mayer, and Albert Y. Lau PNAS, doi: 10.1073/pnas.1607010113 (2016)
Sources and implications of whole-brain fMRI signals in humans Jonathan D Power, Mark Plitt, Timothy O Laumann, Alex Martin Neuroimage, doi://10.1016/j.neuroimage.2016.09.038 (2016)
Diagnosis of Parkinson's disease on the basis of clinical-genetic classification: a population-based modelling study Mike A. Nalls, Cory Y. McLean et al. Lancet Neurol., doi: 10.1016/S1474-4422(15)00178-7 (2016)
Microenvironmental Gene Expression Plasticity Among Individual Drosophila melanogaster Lin, Y; Chen, ZX; Oliver, B; Harbison, ST; G3 (Bethesda), DOI://10.1534/g3.116.035444 (2016)

A RUNX2-Mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells Shin, MH; He, Y; Marrogi, E et al. PLoS Genet., DOI://10.1371/journal.pgen.1005884 (2016)
Sp5 and Sp8 recruit β-catenin and Tcf1-Lef1 to select enhancers to activate Wnt target gene transcription Kennedy, MW; Chalamalasetty, RB; Thomas, S; Garriock, RJ; Jailwala, P; Yamaguchi, TP; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1519994113 (2016)
Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number Lyons, JJ; Yu, X; Hughes, JD et al. Nat. Genet., DOI://10.1038/ng.3696 (2016)
Hydrogen Bonding to the substrate is not required for Rieske iron-sulfur protein docking to the quinol oxidation site of complex III Lothar Esser, Fei Zhou, Yihui Zhou, Yumei Xiao, Wai-kwan Tang, Chang-An Yu, Zhaohai Qin and Di Xia J. Biol. Chem., doi: 10.1074/jbc.M116.744391 (2016)
SARAH Domain-Mediated MST2-RASSF Dimeric Interactions Goar Sànchez-Sanz , Bartomiej Tywoniuk , David Matallanas, David Romano, Lan K. Nguyen, Boris N. Kholodenko, Edina Rosta , Walter Kolch , Nicolae-Viorel Buchete PLoS Computational Biology, doi://10.1371/journal.pcbi.1005051 (2016)
Systems-level analysis reveals selective regulation of Aqp2 gene expression by vasopressin Sandoval, PC; Claxton, JS; Lee, JW; Saeed, F; Hoffert, JD; Knepper, MA; Sci Rep, DOI://10.1038/srep34863 (2016)
Evaluation of KIR3DL1/KIR3DS1 polymorphism in Behçet's disease Erer, B; Takeuchi, M; Ustek, D et al. Genes Immun., DOI://10.1038/gene.2016.36 (2016)
Rapid development of a DNA vaccine for Zika virus Dowd, KA; Ko, SY; Morabito, KM et al. Science, DOI://10.1126/science.aai9137 (2016)
Blind prediction of distribution in the SAMPL5 challenge with QM based protomer and pKa corrections Frank C. Pickard IV, Gerhard König, Florentina Tofoleanu, Juyong Lee, Andrew C. Simmonett, Yihan Shao, Jay W. Ponder, Bernard R. Brooks J. Computer-Aided Molecular Design, DOI: 10.1007/s10822-016-9955-7 (2016)
A Modified P1 Moiety Enhances in vitro Antiviral Activity against Various Multi-Drug-Resistant HIV-1 Variants and in vitro CNS Penetration Properties of a Novel Nonpeptidic Protease Inhibitor, GRL-10413 Masayuki Amano, Pedro Miguel Salcedo-Gomez, Rui Zhao, Ravikiran S. Yedidi, Debananda Das, Haydar Bulut, Nicole S. Delino, Sheri Venkata Reddy, Arun K. Ghosh and Hiroaki Mitsuya Antimicrobial Agents and Chemotherapy, doi: 10.1128/AAC.01428-16 (2016)
Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations BH Chen, M-F Hivert et al. Diabetes, doi://10.2337/db16-0470 (2016)
On the Selective Packaging of Genomic RNA by HIV-1 Mauricio Comas-Garcia, Sean R. Davis and Alan Rein Viruses, doi://10.3390/v8090246 (2016)

Behavioral and Neural Sustained Attention Deficits in Bipolar Disorder and Familial Risk for Bipolar Disorder David Pagliaccio, Jillian Lee Wiggins, et al. Biological Psychiatry, doi://10.1016/j.biopsych.2016.09.006 (2016)
Mutations of SGO2 and CLDN14 collectively cause coincidental Perrault syndrome R Faridi, AR Rehman et al. Clinical Genetics, DOI: 10.1111/cge.12867 (2016)
CYP2A6 genetic variation alters striatal-cingulate circuits, network hubs, and executive processing in smokers Sufang Li, Yihong Yang, Ewa Hoffmann, Rachel F. Tyndale, Elliot A. Stein Biological Psychiatry, doi://10.1016/j.biopsych.2016.09.013 (2016)
Absolute binding free energies for octa-acids and guests in SAMPL5 Florentina Tofoleanu, Juyong Lee, Frank C. Pickard IV, Gerhard Kzönig, Jing Huang, Minkyung Baek, Chaok Seok, Bernard R. Brooks J. Computer-Aided Molecular Design, DOI: 10.1007/s10822-016-9965-5 (2016)
Introduction, evolution, and dissemination of influenza A viruses in exhibition swine, USA, 2009-2013 Martha I. Nelson, Karla M. Stucker, et al. J. Virology, doi: 10.1128/JVI.01457-16 (2016)
Differential cytokine sensitivities of STAT5-dependent enhancers rely on Stat5 autoregulation Willi, M; Yoo, KH; Wang, C; Trajanoski, Z; Hennighausen, L; Nucleic Acids Res., DOI://10.1093/nar/gkw844 (2016)
Novel genetic loci underlying human intracranial volume identified through genome-wide association Adams, HH; Hibar, DP; Chouraki, V et al. Nat. Neurosci., DOI://10.1038/nn.4398 (2016)
DNA methylation-based measures of biological age: meta-analysis predicting time to death Chen, BH; Marioni, RE; Colicino, E et al. Aging (Albany NY), DOI://10.18632/aging.101020 (2016)
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals Ehret, GB; Ferreira, T; Chasman, DI et al. Nat. Genet., DOI://10.1038/ng.3667 (2016)
Characterization and phosphoproteomic analysis of a human immortalized podocyte model of Fabry disease generated using CRISPR/Cas9 technology Pereira, EM; Labilloy, A; Eshbach, ML et al. Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00283.2016 (2016)
Alternative Isoform Analysis of Ttc8 Expression in the Rat Pineal Gland Using a Multi-Platform Sequencing Approach Reveals Neural Regulation Hartley, SW; Mullikin, JC; Klein, DC; Park, M; , ; Coon, SL; PLoS ONE, DOI://10.1371/journal.pone.0163590 (2016)
Oncogenic Mutations Differentially Affect Bax Monomer, Dimer, and Oligomeric Pore Formation in the Membrane Mingzhen Zhang, Jie Zheng, Ruth Nussinov, Buyong Ma Scientific Reports, 10.1038/srep33340 (2016)
Integrative Transcriptome Analyses of Metabolic Responses in Mice Define Pivotal LncRNA Metabolic Regulators Yang, L; Li, P; Yang, W et al. Cell Metab., DOI://10.1016/j.cmet.2016.08.019 (2016)
REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants Ioannidis, NM; Rothstein, JH; Pejaver, V et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2016.08.016 (2016)
Daily physical activity patterns from hip- and wrist-worn accelerometers Shiroma, EJ; Schepps, MA; Harezlak, J et al. Physiol Meas, DOI://10.1088/0967-3334/37/10/1852 (2016)
Association of Superoxide Dismutase 2 (SOD2) Genotype with Gray Matter Volume Shrinkage in Chronic Alcohol Users: Replication and Further Evaluation of an Addiction Gene Panel Gitik M, Srivastava V, Hodgkinson CA, Shen PH, Goldman D, Meyerhoff DJ Int. J. Neuropsychopharmacol., DOI://10.1093/ijnp/pyw033 (2016)
DNA Transposition at Work Hickman, AB; Dyda, F; Chem. Rev., DOI://10.1021/acs.chemrev.6b00003 (2016)
Expression, purification and identification of a thermolysin-like protease, neutral protease I, from Aspergillus oryzae with the Pichia pastoris expression system Ma, X; Liu, Y; Li, Q et al. Protein Expr. Purif., DOI://10.1016/j.pep.2016.08.008 (2016)

The African diaspora: history, adaptation and health Rotimi CN, Tekola-Ayele F, Baker JL, Shriner D Curr. Opin. Genet. Dev., DOI://10.1016/j.gde.2016.08.005 (2016)
3D-printed head models for navigated non-invasive brain stimulation Dayan, E; Thompson, RM; Buch, ER; Cohen, LG; Clin Neurophysiol, DOI://10.1016/j.clinph.2016.08.011 (2016)
Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder Hou, L; Bergen, SE; Akula, N et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddw181 (2016)
Distinct fMRI Responses to Self-Induced versus Stimulus Motion during Free Viewing in the Macaque Russ, BE; Kaneko, T; Saleem, KS; Berman, RA; Leopold, DA; J. Neurosci., DOI://10.1523/JNEUROSCI.1152-16.2016 (2016)
A genome-wide association study in multiple system atrophy Sailer, A; Scholz, SW; Nalls, MA et al. Neurology, DOI://10.1212/WNL.0000000000003221 (2016)
An efficient protocol for obtaining accurate hydration free energies using quantum chemistry and reweighting from molecular dynamics simulations Frank C. Pickard, Gerhard Koenig, Andrew C. Simmonett, Yihan Shao, Bernard R. Brooks Bioorganic & Medicinal Chemistry, doi://10.1016/j.bmc.2016.08.031 (2016)

Skin microbiome before development of atopic dermatitis: Early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year s: Kennedy EA, Connolly J, O'B Hourihane J, Fallon PG, McLean WI, Murray D, Jo J-H, Segre JA, Kong HH, Irvine AD J. Allergy and Clinical Immunology , doi: 10.1016/j.jaci.2016.07.029 (2016)
Effects of Gene Dose, Chromatin, and Network Topology on Expression in Drosophila melanogaster Hangnoh Lee, Dong-Yeon Cho, Cale Whitworth, Robert Eisman, Melissa Phelps, John Roote, Thomas Kaufman, Kevin Cook, Steven Russell, Teresa Przytycka, Brian Oliver PLoS Genetics, doi://10.1371/journal.pgen.1006295 (2016)
Diverse Human Skin Fungal Communities in Children Converge in Adulthood Jo, JH; Deming, C; Kennedy, EA et al. J. Invest. Dermatol., DOI://10.1016/j.jid.2016.05.130 (2016)
A Model for Transposition of the Colistin Resistance Gene mcr-1 by ISApl1 Snesrud, E; He, S; Chandler, M et al. Antimicrob. Agents Chemother., DOI://10.1128/AAC.01457-16 (2016)
Transferability of genome-wide associated loci for asthma in African Americans Faruque, MU; Chen, G; Doumatey, AP et al. J Asthma, DOI://10.1080/02770903.2016.1188941 (2016)
Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease Zhou, Q; Yu, X; Demirkaya, E et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1612594113 (2016)

GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium Matteini, AM; Tanaka, T; Karasik, D et al. Aging Cell, DOI://10.1111/acel.12468 (2016)
Quantifying antiepileptic drug effects using intrinsic excitability measures Christian Meisel, Dietmar Plenz, Andreas Schulze-Bonhage, Heinz Reichmann Epilepsia, DOI: 10.1111/epi.13517 (2016)
Genetic causes of moderate to severe hearing loss point to modifiers S. Naz, A. Imtiaz et al. Clinical Genetics, DOI: 10.1111/cge.12856 (2016)
Bi-allelic Truncating Mutations in CEP78, Encoding Centrosomal Protein 78, Cause Cone-Rod Degeneration with Sensorineural Hearing Loss Prasanthi Namburi, Rinki Ratnapriya et al. Am. J. Hum. Genet., doi://10.1016/j.ajhg.2016.07.010 (2016)
Structural basis of kainate subtype glutamate receptor desensitization Joel R. Meyerson, Sagar Chittori, Alan Merk, Prashant Rao, Tae Hee Han, Mihaela Serpe, Mark L. Mayer & Sriram Subramaniam Nature, doi:10.1038/nature19352 (2016)
Probing the Action of Chemical Denaturant on an Intrinsically Disordered Protein by Simulation and Experiment Wenwei Zheng, Alessandro Borgia, Karin Buholzer, Alexander Grishaev, Benjamin Schuler, and Robert B. Best JACS, DOI: 10.1021/jacs.6b05443 (2016)

Consistent View of Polypeptide Chain Expansion in Chemical Denaturants from Multiple Experimental Methods A Borgia, W Zheng, et al. JACS, DOI: 10.1021/jacs.6b05917 (2016)
HMGN proteins modulate chromatin regulatory sites and gene expression during activation of naïve B cells Zhang, S; Zhu, I; Deng, T et al. Nucleic Acids Res., DOI://10.1093/nar/gkw323 (2016)
Analysis of Ly49 gene transcripts in mature NK cells supports a role for the Pro1 element in gene activation, not gene expression McCullen MV, Li H, Cam M, Sen SK, McVicar DW, Anderson SK Genes Immun., DOI://10.1038/gene.2016.31 (2016)
Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans Evans, DS; Avery, CL; Nalls, MA et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddw284 (2016)
Altered Human Memory Modification in the Presence of Normal Consolidation Censor N, Buch ER, Nader K, Cohen LG Cereb. Cortex, DOI://10.1093/cercor/bhv180 (2016)
Calculating distribution coefficients based on multi-scale free energy simulations: an evaluation of MM and QM/MM explicit solvent simulations of water-cyclohexane transfer in the SAMPL5 challenge König, G; Pickard, FC; Huang, J et al. J. Comput. Aided Mol. Des., DOI://10.1007/s10822-016-9936-x (2016)

Pleiotropic Analysis of Lung Cancer and Blood Triglycerides Zuber, V; Marconett, CN; Shi, J et al. J. Natl. Cancer Inst., DOI://10.1093/jnci/djw167 (2016)
Three-Dimensional Digital Template Atlas of the Macaque Brain Reveley, C; Gruslys, A; Ye, FQ et al. Cereb. Cortex, DOI://10.1093/cercor/bhw248 (2016)
Early-Childhood Social Reticence Predicts Brain Function in Preadolescent Youths During Distinct Forms of Peer Evaluation Jarcho JM, Davis MM, Shechner T, Degnan KA, Henderson HA, Stoddard J, Fox NA, Leibenluft E, Pine DS, Nelson EE Psychol Sci., doi: 10.1177/0956797616638319 (2016)
Global diversity in the TAS2R38 bitter taste receptor: revisiting a classic evolutionary PROPosal Risso DS, Mezzavilla M et al. Sci Rep., doi: 10.1038/srep25506 (2016)
A Deep Insight into the Sialome of Male and Female Aedes aegypti Mosquitoes Ribeiro JM, Martin-Martin I, Arcà B, Calvo E PLoS One., doi: 10.1371/journal.pone.0151400 (2016)
Noise Estimation and Reduction in Multispectral Magnetic Resonance Images Bouhrara M, Bonny JM, Ashinsky B, Maring M, Spencer R IEEE Trans Med Imaging, DOI://10.1109/TMI.2016.2601243 (2016)

Internal Proteins of the Procapsid and Mature Capsids of Herpes Simplex Virus 1 Mapped by Bubblegram Imaging Wu W, Newcomb WW, Cheng N, Aksyuk A, Winkler DC, Steven AC J Virol. , doi: 10.1128/JVI.03224-15 (2016)
A Deep Insight into the Sialome of Rhodnius neglectus, a Vector of Chagas Disease Santiago PB, Assumpcao TC et al. PLoS Negl Trop Dis., doi: 10.1371/journal.pntd.0004581 (2016)
A Class of Diacylglycerol Acyltransferase 1 Inhibitors Identified by a Combination of Phenotypic High-throughput Screening, Genomics, and Genetics Tschapalda K, Zhang YQ et al. EBioMedicine., doi: 10.1016/j.ebiom.2016.04.014 (2016)
Age-related differences in the neural correlates of trial-to-trial variations of reaction time Adleman NE, Chen G, Reynolds RC, Frackman A, Razdan V, Weissman DH, Pine DS, Leibenluft E Dev Cogn Neurosci., doi: 10.1016/j.dcn.2016.05.001. (2016)
Copy Number Variation in TAS2R Bitter Taste Receptor Genes: Structure, Origin, and Population Genetics Roudnitzky N, Risso D, Drayna D, Behrens M, Meyerhof W, Wooding SP Chem Senses., DOI: 10.1093/chemse/bjw067 (2016)
Linking Genes and Brain Development of Honeybee Workers: A Whole-Transcriptome Approach Vleurinck C, Raub S, Sturgill D, Oliver B, Beye M PLoS One, doi: 10.1371/journal.pone.0157980 (2016)

Preliminary differences in resting state MEG functional connectivity pre- and post-ketamine in major depressive disorder Nugent AC, Robinson SE, Coppola R, Zarate CA Psychiatry Res, DOI://10.1016/j.pscychresns.2016.06.006 (2016)
Structure-Based Screening of Uncharted Chemical Space for Atypical Adenosine Receptor Agonists Rodríguez, D; Chakraborty, S; Warnick, E et al. ACS Chem. Biol., DOI://10.1021/acschembio.6b00357 (2016)
Amygdala response to explicit sad face stimuli at baseline predicts antidepressant treatment response to scopolamine in major depressive disorder Szczepanik, J; Nugent, AC; Drevets, WC; Khanna, A; Zarate, CA; Furey, ML; Psychiatry Res, DOI://10.1016/j.pscychresns.2016.06.005 (2016)
Global intron retention mediated gene regulation during CD4+ T cell activation Ni, T; Yang, W; Han, M et al. Nucleic Acids Res., DOI://10.1093/nar/gkw591 (2016)
An interactive web-based application for Comprehensive Analysis of RNAi-screen Data Dutta B, Azhir A et al. Nature Communications, doi: 10.1038/ncomms10578. (2016)
Neural Correlates of Irritability in Disruptive Mood Dysregulation and Bipolar Disorders Wiggins JL, Brotman MA, Adleman NE, Kim P, Oakes AH, Reynolds RC, Chen G, Pine DS, Leibenluft E Am J Psychiatry., doi: 10.1176/appi.ajp.2015.15060833 (2016)

Genomic insights into the Ixodes scapularis tick vector of Lyme disease Gulia-Nuss M, Nuss AB et al. Nat Commun. , doi: 10.1038/ncomms10507 (2016)
Prefrontal GABA Levels Measured With Magnetic Resonance Spectroscopy in Patients With Psychosis and Unaffected Siblings Marenco S, Meyer C, Kuo S, van der Veen JW, Shen J, DeJong K, Barnett AS, Apud JA, Dickinson D, Weinberger DR, Berman KF Am J Psychiatry, doi: 10.1176/appi.ajp.2015 (2016)
Rare copy number variants implicated in posterior urethral valves Boghossian NS, Sicko RJ et al Am J Med Genet A., doi: 10.1002/ajmg.a.37493 (2016)
Computational evaluation of exome sequence data using human and model organism phenotypes improves diagnostic efficiency Bone WP, Washington NL et al. Genet Med, doi: 10.1038/gim.2015.137 (2016)
TCRβ repertoire of CD4+ and CD8+ T cells is distinct in richness, distribution, and CDR3 amino acid composition Li HM, Hiroi T, Zhang Y, Shi A, Chen G, De S, Metter EJ, Wood WH rd, Sharov A, Milner JD, Becker KG, Zhan M, Weng NP J Leukoc Biol., doi: 10.1189/jlb.6A0215-071RR (2016)
Neural correlates of masked and unmasked face emotion processing in youth with severe mood dysregulation Tseng WL, Thomas LA, Harkins E, Pine DS, Leibenluft E, Brotman MA Soc Cogn Affect Neurosci, doi: 10.1093/scan/nsv087 (2016)

Evolving specificity of tRNA 3-methyl-cytidine-32 (m3C32) modification: a subset of tRNAsSer requires N6-isopentenylation of A37 Arimbasseri, AG; Iben, J; Wei, FY et al. RNA, DOI://10.1261/rna.056259.116 (2016)
Estimating relative risk of a log-transformed exposure measured in pools Mitchell EM, Plowden TC, Schisterman EF Stat Med, DOI://10.1002/sim.7075 (2016)
Phosphorylation of residues inside the SNARE complex suppresses secretory vesicle fusion Malmersjo, S; Di Palma, S; Diao, J et al. EMBO J., DOI://10.15252/embj.201694071 (2016)
Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration Yu Chen, Grazyna Palczewska, et al. Sci Signal. , doi: 10.1126/scisignal.aag0245 (2016)
A simple but useful way to assess fMRI scan qualities Jonathan D. Power NeuroImage, doi:10.1016/j.neuroimage.2016.08.009 (2016)
Conformational dynamics of cancer-associated MyD88-TIR domain mutant L252P (L265P) allosterically tilts the landscape toward homo-dimerization Chendi Zhan, Ruxi Qi, Guanghong Wei, Emine Guven-Maiorov, Ruth Nussinov and Buyong Ma Protein Engineering, Design and Selection, doi: 10.1093/protein/gzw033 (2016)

Altered striatal intrinsic functional connectivity in pediatric anxiety Dorfman J, Benson B, Farber M, Pine D, Ernst M Neuropsychologia, doi: 10.1016/j.neuropsychologia.2016.03.019 (2016)
Next-generation sequencing reveals substantial genetic contribution to dementia with Lewy bodies Geiger, JT; Ding, J; Crain, B et al. Neurobiol. Dis., DOI://10.1016/j.nbd.2016.06.004 (2016)
Commonalities in Development of Pure Breeds and Population Isolates Revealed in the Genome of the Sardinian Fonni's Dog Dreger, DL; Davis, BW; Cocco, R et al. Genetics, DOI://10.1534/genetics.116.192427 (2016)
An Enantiomer of an Oral Small-Molecule TSH Receptor Agonist Exhibits Improved Pharmacologic Properties Neumann, S; Padia, U; Cullen, MJ et al. Front Endocrinol (Lausanne), DOI://10.3389/fendo.2016.00105 (2016)
Coffee Drinking Is Widespread in the United States but Usual Intake Varies by Key Demographic and Lifestyle Factors Erikka Loftfield, Neal D Freedman, Kevin W Dodd, Emily Vogtmann, Qian Xiao, Rashmi Sinha, and Barry I Graubard J. Nutrition, doi: 10.3945/jn.116.233940 (2016)
PreSMA stimulation changes task-free functional connectivity in the fronto-basal-ganglia that correlates with response inhibition efficiency Xu, B; Sandrini, M; Wang, WT et al. Hum Brain Mapp, DOI://10.1002/hbm.23236 (2016)

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals John D. Eicher, Nathalie Chami, et al. Am. J. Hum. Genet. , doi://10.1016/j.ajhg.2016.05.005 . (2016)
AptaTRACE Elucidates RNA Sequence-Structure Motifs from Selection Trends in HT-SELEX Experiments Phuong Dao, Jan Hoinka, Mayumi Takahashi, Jiehua Zhou, Michelle Ho, Yijie Wang, Fabrizio Costa, John J. Rossi, Rolf Backofen, John Burnett, Teresa M. Przytycka Cell Systems, doi:10.1016/j.cels.2016.07.003 (2016)
C-5-Modified Tetrahydropyrano-Tetrahydofuran-Derived Protease Inhibitors (PIs) Exert Potent Inhibition of the Replication of HIV-1 Variants Highly Resistant to Various PIs, including Darunavir Manabu Aoki, Hironori Hayashi, Ravikiran S. Yedidi, Cuthbert D. Martyr, Yuki Takamatsu, Hiromi Aoki-Ogat, Teruya Nakamura, Hirotomo Nakata, Debananda Das, Yuriko Yamagata, Arun K. Ghosh and Hiroaki Mitsuya J. Virology, doi: 10.1128/JVI.01829-15 (2016)
SMAC mimetic birinapant plus radiation eradicates human head and neck cancers with genomic amplifications of cell death genes FADD and BIRC2 Danielle F Eytan, Grace E Snow, Sophie Carlson, Adeeb Derakhshan, Anthony Saleh, Stephen Schiltz, Hui Cheng, Suresh Mohan, Shaleeka Cornelius, Jamie F Coupar, Anastasia L. Sowers, Lidia Hernandez, James B. Mitchell, Christina M. Annunziata, Zhong Chen, Carter Van Waes Cancer Research, DOI: 10.1158/0008-5472.CAN-15-3317 (2016)
Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies. Demirkan A, Lahti J et al Psychol Med, doi: 10.1017/S0033291715002081 (2016)
Modeling RNA topological structures using small angle X-ray scattering Yuba R. Bhandari, Wei Jiang, Eric A. Stahlberg, Jason R. Stagno, Yun-Xing Wang Methods, doi:10.1016/j.ymeth.2016.04.015 (2016)

Comparing biomarkers as trial level general surrogates Erin E Gabriel, Michael J. Daniels, M. Elizabeth Halloran Biometrics, DOI: 10.1111/biom.12513 (2016)
Diffusive Dynamics of Contact Formation in Disordered Polypeptides Gül H. Zerze, Jeetain Mittal, and Robert B. Best Phys. Rev. Lett., doi://10.1103/PhysRevLett.116.068102 (2016)
Genome-wide cooperation by HAT Gcn5, remodeler SWI/SNF, and chaperone Ydj1 in promoter nucleosome eviction and transcriptional activation Hongfang Qiu, Razvan V. Chereji, Cuihua Hu, Hope A. Cole, Yashpal Rawal, David J. Clark, and Alan G. Hinnebusch Genome Research, doi: 10.1101/gr.196337.115 (2016)
The evolutionary turnover of recombination hot spots contributes to speciation in mice Fatima Smagulova, Kevin Brick, Yongmei Pu, R. Daniel Camerini-Otero, and Galina V. Petukhova Genes. Dev. , doi: 10.1101/gad.270009.115 (2016)
Origins of the 2009 H1N1 influenza pandemic in swine in Mexico Ignacio Mena, Martha I Nelson, et al. eLife, doi://10.7554/eLife.16777 (2016)
A Powerful Procedure for Pathway-Based Meta-analysis Using Summary Statistics Identifies 43 Pathways Associated with Type II Diabetes in European Populations Han Zhang, William Wheeler, Paula L. Hyland, Yifan Yang, Jianxin Shi, Nilanjan Chatterjee, and Kai Yu PLoS Genetics, doi: 10.1371/journal.pgen.1006122 (2016)

Evaluation of multi-echo ICA denoising for task based fMRI studies: Block designs, rapid event-related designs, and cardiac-gated fMRI Javier Gonzalez-Castillo, Puja Panwar, Laura C. Buchanan, Cesar Caballero-Gaudes, Daniel A. Handwerker, David C. Jangraw, Valentinos Zachariou, Souheil Inati, Vinai Roopchansingh, John A. Derbyshire, Peter A. Bandettini NeuroImage, doi:10.1016/j.neuroimage.2016.07.049 (2016)
Rare Variants Analysis of Cutaneous Malignant Melanoma Genes in Parkinson's Disease S.J. Lubbe, V. Escott-Price et al, the Melanoma Meta-Analysis Consortium, the International Parkinson's Disease Genomics Consortium Neurobiology of Aging, doi:10.1016/j.neurobiolaging.2016.07.013 (2016)
Crystal structure of the antigen-binding fragment of a monoclonal antibody specific for the multidrug-resistance-linked ABC transporter human P-glycoprotein Lothar Esser, Suneet Shukla, Fei Zhou, Suresh V. Ambudkar and Di Xia Acta Cryst. F, doi:10.1107/S2053230X16009778 (2016)
Certified DNA Reference Materials to Compare HER2 Gene Amplification Measurements Using Next-Generation Sequencing Methods Chih-Jian Lih, Han Si et al. J. Mol. Diag. , doi:10.1016/j.jmoldx.2016.05.008 (2016)
Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses Joyce, MG; Wheatley, AK; Thomas, PV et al. Cell, DOI://10.1016/j.cell.2016.06.043 (2016)
Characterizing human lung tissue microbiota and its relationship to epidemiological and clinical features Yu, G; Gail, MH; Consonni, D et al. Genome Biol., DOI://10.1186/s13059-016-1021-1 (2016)

Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies Joshi, AD; Andersson, C; Buch, S et al. Gastroenterology, DOI://10.1053/j.gastro.2016.04.007 (2016)
Polybrominated Diphenyl Ethers: Structure Determination and Trends in Antibacterial Activity Liu, H; Lohith, K; Rosario, M et al. J. Nat. Prod., DOI://10.1021/acs.jnatprod.6b00229 (2016)
Association of Maternal Prepregnancy Dyslipidemia With Adult Offspring Dyslipidemia in Excess of Anthropometric, Lifestyle, and Genetic Factors in the Framingham Heart Study Mendelson MM, Lyass A, O'Donnell CJ, D'Agostino RB, Levy D JAMA Cardiol, DOI://10.1001/jamacardio.2015.0304 (2016)
Comparison of Sedentary Estimates between activPAL and Hip- and Wrist-Worn ActiGraph Koster, A; Shiroma, EJ; Caserotti, P et al. Med Sci Sports Exerc, DOI://10.1249/MSS.0000000000000924 (2016)
Design strategies to address the effect of hydrophobic epitope on stability and in vitro assembly of modular virus-like particle Tekewe, A; Connors, NK; Middelberg, AP; Lua, LH; Protein Sci., DOI://10.1002/pro.2953 (2016)
South (S)- and North (N)-Methanocarba-7-Deazaadenosine Analogues as Inhibitors of Human Adenosine Kinase Kiran S. Toti, Danielle Osborne, Antonella Ciancetta, Detlev Boison, and Kenneth A. Jacobson J. Med. Chem. , DOI: 10.1021/acs.jmedchem.6b00689 (2016)

Change in Epigenome-Wide DNA Methylation Over 9 Years and Subsequent Mortality: Results From the InCHIANTI Study Moore, AZ; Hernandez, DG; Tanaka, T et al. J. Gerontol. A Biol. Sci. Med. Sci., DOI://10.1093/gerona/glv118 (2016)
Computational study of the inhibitory mechanism of the kinase CDK5 hyperactivity by peptide p5 and derivation of a pharmacophore A. Cardone, M. Brady, R. Sriram, H. C. Pant, S. A. Hassan J. Computer-Aided Molecular Design, DOI: 10.1007/s10822-016-9922-3 (2016)
A Comparison Study of Fixed and Mixed Effect Models for Gene Level Association Studies of Complex Traits Ruzong Fan, Chi-yang Chiu, Jeesun Jung, Daniel E. Weeks, Alexander F. Wilson, Joan E. Bailey-Wilson, Christopher I. Amos, Zhen Chen, James L. Mills and Momiao Xiong Genetic Epidemiology, DOI: 10.1002/gepi.21984 (2016)
Mutational Spectrum of MYO15A and the Molecular Mechanisms of DFNB3 Human Deafness Atteeq U. Rehman, Jonathan E. Bird, Rabia Faridi, Mohsin Shahzad, Sujay Shah, Kwanghyuk Lee, Shaheen N. Khan, Ayesha Imtiaz, Zubair M. Ahmed, Saima Riazuddin, Regie Lyn P. Santos- Cortez, Wasim Ahmad, Suzanne M. Leal, Sheikh Riazuddin, Thomas B. Friedman Human Mutation, DOI: 10.1002/humu.23042 (2016)
Transmission-blocking activity is determined by transmission-reducing activity and number of control oocysts in Plasmodium falciparum standard membrane-feeding assay Kazutoyo Miura, Bruce J. Swihart, Bingbing Deng, Luwen Zhou, Thao P. Pham, Ababacar Diouf, Timothy Burton, Michael P. Fay, Carole A. Long Vaccine, doi:10.1016/j.vaccine.2016.06.066 (2016)
Tyrosine-sulfated V2 peptides inhibit HIV-1 infection via coreceptor mimicry Raffaello Cimbro, Francis C. Peterson, Qingbo Liu, Christina Guzzo, Peng Zhang, Huiyi Miao, Donald Van Ryk, Xavier Ambroggio, Darrell E. Hurt, Luca De Gioia, Brian F. Volkman, Michael A. Dolan, Paolo Lusso EBioMedicine, doi:10.1016/j.ebiom.2016.06.037 (2016)
Complete Genome Sequence of a Klebsiella pneumoniae Strain Carrying blaNDM-1 on a Multidrug Resistance Plasmid Conlan S, Lau AF, , Palmore TN, Frank KM, Segre JA Genome Announc, DOI://10.1128/genomeA.00664-16 (2016)
A Cascade of Wnt, Eda, and Shh Signaling Is Essential for Touch Dome Merkel Cell Development Xiao, Y; Thoresen, DT; Miao, L et al. PLoS Genet., DOI://10.1371/journal.pgen.1006150 (2016)
Defining the neuroanatomic basis of motor coordination in children and its relationship with symptoms of attention-deficit/hyperactivity disorder Shaw, P; Weingart, D; Bonner, T et al. Psychol Med, DOI://10.1017/S0033291716000660 (2016)
Common Variation in the DOPA Decarboxylase (DDC) Gene and Human Striatal DDC Activity In Vivo Eisenberg, DP; Kohn, PD; Hegarty, CE et al. Neuropsychopharmacology, DOI://10.1038/npp.2016.31 (2016)
Improving Motor Corticothalamic Communication After Stroke Using Real-Time fMRI Connectivity-Based Neurofeedback Liew, SL; Rana, M; Cornelsen, S et al. Neurorehabil Neural Repair, DOI://10.1177/1545968315619699 (2016)
Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits Chami, N; Chen, MH; Slater, AJ et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2016.05.007 (2016)

Pathogenic role of B-cell receptor signaling and canonical NF-κB activation in mantle cell lymphoma Saba, NS; Liu, D; Herman, SE et al. Blood, DOI://10.1182/blood-2015-11-681460 (2016)
Chromatin Landscape of the IRF Genes and Role of the Epigenetic Reader BRD4 Bachu, M; Dey, A; Ozato, K; J. Interferon Cytokine Res., DOI://10.1089/jir.2015.0179 (2016)
Fine-tuning of CD8(+) T-cell effector functions by targeting the 2B4-CD48 interaction Lissina, A; Ambrozak, DR; Boswell, KL et al. Immunol. Cell Biol., DOI://10.1038/icb.2016.17 (2016)
Dataset of Arabidopsis plants that overexpress FT driven by a meristem-specific KNAT1 promoter Duplat-Bermúdez, L; Ruiz-Medrano, R; Landsman, D; Mariño-Ramírez, L; Xoconostle-Cázares, B; Data Brief, DOI://10.1016/j.dib.2016.06.002 (2016)
Structure-Based Design of 3-(4-Aryl-1H-1,2,3-triazol-1-yl)-Biphenyl Derivatives as P2Y14 Receptor Antagonists Anna Junker, Ramachandran Balasubramanian, Antonella Ciancetta, Elisa Uliassi, Evgeny Kiselev, Chiara Martiriggiano, Kevin Trujillo, Giorgi Mtchedlidze, Leah Birdwell, Kyle A. Brown, T. Kendall Harden, and Kenneth A. Jacobson J. Med. Chem. , DOI: 10.1021/acs.jmedchem.6b00044 (2016)
Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases Salman M. Tajuddin, Ursula M. Schick et al. Am. J. Hum. Genet., doi:10.1016/j.ajhg.2016.05.003 (2016)

Plasmid Dynamics in KPC-Positive Klebsiella pneumoniae during Long-Term Patient Colonization Conlan, S; Park, M; Deming, C et al. MBio, DOI://10.1128/mBio.00742-16 (2016)
The genetic regulatory signature of type 2 diabetes in human skeletal muscle Scott, LJ; Erdos, MR; Huyghe, JR et al. Nat Commun, DOI://10.1038/ncomms11764 (2016)
Coarse Master Equations for Binding Kinetics of Amyloid Peptide Dimers Cathal T. Leahy, Ronan D. Murphy, Gerhard Hummer, Edina Rosta, and Nicolae-Viorel Buchete J. Phys. Chem. Lett., DOI: 10.1021/acs.jpclett.6b00518 (2016)
Recruitment of Rod Photoreceptors from Short-Wavelength-Sensitive Cones during the Evolution of Nocturnal Vision in Mammals Jung-Woong Kim, Hyun-Jin Yang, Adam Phillip Oel, Matthew John Brooks, Li Jia, David Charles Plachetzki, Wei Li, William Ted Allison, Anand Swaroop Developmental Cell, doi:10.1016/j.devcel.2016.05.023 (2016)
Enhanced exo-inulinase activity and stability by fusion of an inulin-binding module Shun-Hua Zhou, Yuan Liu, Yu-Juan Zhao, Zhe Chi, Zhen-Ming Chi, Guang-Lei Liu Applied Microbiology and Biotechnology, doi:10.1007/s00253-016-7587-4 (2016)
Ring Catalog: A resource for designing self-assembling RNA nanostructures Parlea, L; Bindewald, E; Sharan, R et al. Methods, DOI://10.1016/j.ymeth.2016.04.016 (2016)

Decreased subcortical volumes in alcohol dependent individuals: effect of polysubstance use disorder Grodin EN, Momenan R Addict Biol, DOI://10.1111/adb.12421 (2016)
Compressed Sensing Electron Tomography for Determining Biological Structure Matthew D. Guay, Wojciech Czaja, Maria A. Aronova & Richard D. Leapman Nature, doi:10.1038/srep27614 (2016)
Next generation sequencing technology and genomewide data analysis: Perspectives for retinal research Vijender Chaitankar, Gokhan Karakulah, Rinki Ratnapriya, Felipe O. Giuste, Matthew J. Brooks, Anand Swaroop Progress in Retinal and Eye Research, doi:10.1016/j.preteyeres.2016.06.001 (2016)
Taz1-Shelterin Promotes Facultative Heterochromatin Assembly at Chromosome-Internal Sites Containing Late Replication Origins Zofall M, Smith DR, Mizuguchi T, Dhakshnamoorthy J, Grewal SI Mol. Cell, DOI://10.1016/j.molcel.2016.04.034 (2016)
The homeoprotein DLX3 and tumor suppressor p53 co-regulate cell cycle progression and squamous tumor growth Palazzo, E; Kellett, M; Cataisson, C et al. Oncogene, DOI://10.1038/onc.2015.380 (2016)
Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8 Soto, C; Ofek, G; Joyce, MG et al. PLoS ONE, DOI://10.1371/journal.pone.0157409 (2016)

Impact of Type 2 Diabetes on Impaired Kidney Function in Sub-Saharan African Populations Adebamowo, SN; Adeyemo, AA; Tekola-Ayele, F et al. Front Endocrinol (Lausanne), DOI://10.3389/fendo.2016.00050 (2016)
Mapping of Ebolavirus Neutralization by Monoclonal Antibodies in the ZMapp Cocktail Using Cryo-Electron Tomography and Studies of Cellular Entry Erin E. H. Tran, Elizabeth A. Nelson, Pranay Bonagiri, James A. Simmons, Charles J. Shoemaker, Connie S . Schmaljohn, Gary P. Kobinger, Larry Zeitlin, Sriram Subramaniam, and Judith M. White J. Virol., doi:10.1128/JVI.00406-16 (2016)
Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response M L Nickerson, N Witte, K M Im, S Turan, C Owens, K Misner, S X Tsang, Z Cai, S Wu, M Dean, J C Costello and D Theodorescu Oncogene, doi: 10.1038/onc.2016.172 (2016)
Regulation of normal B-cell differentiation and malignant B-cell survival by OCT2 Hodson, DJ; Shaffer, AL; Xiao, W et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1600557113 (2016)
A replicator-specific binding protein essential for site-specific initiation of DNA replication in mammalian cells Zhang, Y; Huang, L; Fu, H et al. Nat Commun, DOI://10.1038/ncomms11748 (2016)
Decreased Expression of Retinoid X Receptors During Human and Azoxymethane-induced Colorectal Carcinogenesis in the Rat Hao, X; Xiao, H; Ju, J; Hewitt, SM; Morse, HC; Anticancer Res., 1791-7530 (2016)

Chemoreception and neuroplasticity in respiratory circuits William H. Barnett, Ana P. Abdala, Julian F.R. Paton, Ilya A. Rybak, Daniel B. Zoccal, Yaroslav I. Molkov Experimental Neurology, doi:10.1016/j.expneurol.2016.05.036 (2016)
A novel complete-case analysis to determine statistical significance between treatments in an intention-to-treat population of randomized clinical trials involving missing data Wei Liu, Jinhui Ding Stat. Methods in Med. Res. , doi: 10.1177/0962280216651307 (2016)
H19ICR mediated transcriptional silencing does not require target promoter methylation Gebert C, Rong Q, Jeong S, Iben J, Pfeifer K Biochem. Biophys. Res. Commun., DOI://10.1016/j.bbrc.2016.05.042 (2016)
Urinary Metabolite Risk Biomarkers of Lung Cancer: A Prospective Cohort Study Haznadar, M; Cai, Q; Krausz, KW et al. Cancer Epidemiol. Biomarkers Prev., DOI://10.1158/1055-9965.EPI-15-1191 (2016)
Polycomb Ezh2 controls the fate of GABAergic neurons in the embryonic cerebellum Feng, X; Juan, AH; Wang, HA; Ko, KD; Zare, H; Sartorelli, V; Development, DOI://10.1242/dev.132902 (2016)
Prenatal immune programming of the sex-dependent risk for major depression Gilman, SE; Cherkerzian, S; Buka, SL; Hahn, J; Hornig, M; Goldstein, JM; Transl Psychiatry, DOI://10.1038/tp.2016.91 (2016)
Transcriptomic analysis of Arabidopsis overexpressing flowering locus T driven by a meristem-specific promoter that induces early flowering Duplat-Bermúdez, L; Ruiz-Medrano, R; Landsman, D; Mariño-Ramírez, L; Xoconostle-Cázares, B; Gene, DOI://10.1016/j.gene.2016.04.060 (2016)
Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery Alan Merk , Alberto Bartesaghi , Soojay Banerjee , Veronica Falconieri , Prashant Rao , Mindy I. Davis , Rajan Pragani , Matthew B. Boxer , Lesley A. Earl , Jacqueline L.S. Milne , Sriram Subramaniam Cell, doi://10.1016/j.cell.2016.05.040 show (2016)
Robertsonian translocations modify genomic distribution of γH2AFX and H3.3 in mouse germ cells Fayer S, Yu Q, Kim J, Moussette S, Camerini-Otero RD, Naumova AK Mamm. Genome, DOI://10.1007/s00335-016-9630-2 (2016)
Proinflammatory and lipid biomarkers mediate metabolically healthy obesity: A proteomics study Doumatey AP, Zhou J, Zhou M, Prieto D, Rotimi CN, Adeyemo A Obesity (Silver Spring), DOI://10.1002/oby.21482 (2016)
Genome-wide association study identifies 74 loci associated with educational attainment Okbay, A; Beauchamp, JP; Fontana, MA et al. Nature, DOI://10.1038/nature17671 (2016)
Structural Basis for the Failure of the C1 Domain of Ras Guanine Nucleotide Releasing Protein 2 (RasGRP2) to Bind Phorbol Ester with High Affinity Czikora, A; Lundberg, DJ; Abramovitz, A et al. J. Biol. Chem., DOI://10.1074/jbc.M116.725333 (2016)
Encoding of Touch Intensity But Not Pleasantness in Human Primary Somatosensory Cortex Case, LK; Laubacher, CM; Olausson, H; Wang, B; Spagnolo, PA; Bushnell, MC; J. Neurosci., DOI://10.1523/JNEUROSCI.1130-15.2016 (2016)
Trajectories of microsecond molecular dynamics simulations of nucleosomes and nucleosome core particles Alexey K. Shaytan, Grigoriy A. Armeev, Alexander Goncearenco, Victor B. Zhurkin, David Landsman, Anna R. Panchenko Data in Brief, doi:10.1016/j.dib.2016.04.073 (2016)
A Transcriptionally Inactive ATF2 Variant Drives Melanomagenesis Giuseppina Claps, Yann Cheli, Tongwu Zhang, Marzia Scortegagna, Eric Lau, Hyungsoo Kim, Jianfei Qi, Jian-Liang Li, Brian James, Andreas Dzung, Mitchell P. Levesque, Reinhard Dummer, Nicholas K. Hayward, Marcus Bosenberg, Kevin M. Brown, Ze'ev A. Ronai Cell Reports, doi:10.1016/j.celrep.2016.04.072 (2016)
Untangling the relatedness among correlations, part I: Nonparametric approaches to inter-subject correlation analysis at the group level Gang Chen, Yong-Wook Shin, Paul A. Taylor, Daniel Glen, Richard C. Reynolds, Robert B. Israel, Robert W. Cox NeuroImage, doi:10.1016/j.neuroimage.2016.05.023 (2016)
Confidence assignment for mass spectrometry based peptide identifications via the extreme value distribution Gelio Alves and Yi-Kuo Yu Bioinformatics, doi: 10.1093/bioinformatics/btw22 (2016)
A single endoplasmic reticulum aminopeptidase-1 protein allotype is a strong risk factor for Behçet's disease in HLA-B*51 carriers. Takeuchi, M; Ombrello, MJ; Kirino, Y et al. Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2015-209059 (2016)

Ancient Human Migration after Out-of-Africa Shriner D, Tekola-Ayele F, Adeyemo A, Rotimi CN Sci Rep, DOI://10.1038/srep26565 (2016)
Comprehensive Database of Human E3 Ubiquitin Ligases: Application to Aquaporin-2 Regulation Barbara Medvar, Viswanathan Raghuram, Trairak Pisitkun, Abhijit Sarkar, Mark A. Knepper Physiological Genomics, DOI: 10.1152/physiolgenomics.00031.2016 (2016)
Identification of modes of interactions between 9-aminoacridine hydrochloride hydrate and serum proteins by low and high resolution spectroscopy and molecular modeling Piyali Mitra, Uttam Pal, Nakul Chandra Maiti, Anirban Ghosh, Anirban Bhunia and Samita Basu Roy. Soc. Chem. , DOI: 10.1039/C6RA04140J (2016)
OptSSeq: High-throughput sequencing readout of growth enrichment defines optimal gene expression elements for homoethanologenesis Indro Neil Ghosh, and Robert Landick ACS Synthetic Biology, DOI: 10.1021/acssynbio.6b00121 (2016)
Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes Stoehr, A; Yang, Y; Patel, S et al. Cardiovasc. Res., DOI://10.1093/cvr/cvw081 (2016)
Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions Villarino A, Laurence A, Robinson GW, Bonelli M, Dema B, Afzali B, Shih HY, Sun HW, Brooks SR, Hennighausen L, Kanno Y, O'Shea JJ Elife, doi: 10.7554/eLife.08384 (2016)

Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality Han-Yu Shih, Giuseppe Sciumè, Yohei Mikami, Liying Guo, Hong-Wei Sun, Stephen R. Brooks, Joseph F. Urban Jr., Fred P. Davis, Yuka Kanno, John J. O'Shea Cell, doi:10.1016/j.cell.2016.04.029 (2016)
BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin Ballachanda N Devaiah, Chanelle Case-Borden, Anne Gegonne, Chih Hao Hsu, Qingrong Chen, Daoud Meerzaman, Anup Dey, Keiko Ozato & Dinah S Singer Nature Structural & Molecular Biology, doi:10.1038/nsmb.3228 (2016)
Temporal Stability of the Human Skin Microbiome Julia Oh, Allyson L. Byrd , Morgan Park , NISC Comparative Sequencing Program, Heidi H. Kong, Julia A. Segre Cell, doi://10.1016/j.cell.2016.04.008 (2016)
Colorectal Cancer and the Human Gut Microbiome: Reproducibility with Whole-Genome Shotgun Sequencing Emily Vogtmann, Xing Hua, Georg Zeller, Shinichi Sunagawa, Anita Y. Voigt, Rajna Hercog, James J. Goedert, Jianxin Shi, Peer Bork, Rashmi Sinha PLoS One, doi://10.1371/journal.pone.0155362 (2016)
Cryo-EM analysis of the conformational landscape of human P-glycoprotein (ABCB1) during its catalytic cycle Gabriel Frank, Suneet Shukla, Prashant Rao, Mario J Borgnia, Alberto Bartesaghi, Alan Merk, Aerfa Mobin, Lothar Esser, Lesley A. Earl, Michael M Gottesman, Di Xia, Suresh V. Ambudkar, and Sriram Subramaniam Molecular Pharmacology, doi: 10.1124/mol.116.104190 (2016)
Predicting motor improvement after stroke with clinical assessment and diffusion tensor imaging Buch, ER; Rizk, S; Nicolo, P; Cohen, LG; Schnider, A; Guggisberg, AG; Neurology, DOI://10.1212/WNL.0000000000002675 (2016)

Analysis of mcDESPOT- and CPMG-derived parameter estimates for two-component nonexchanging systems Bouhrara M, Reiter DA, Celik H, Fishbein KW, Kijowski R, Spencer RG Magn Reson Med, DOI://10.1002/mrm.25801 (2016)
Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody Kong, R; Xu, K; Zhou, T et al. Science, DOI://10.1126/science.aae0474 (2016)
Interferon Regulator Factor 8 (IRF8) Limits Ocular Pathology during HSV-1 Infection by Restraining the Activation and Expansion of CD8+ T Cells Sun, L; St Leger, AJ; Yu, CR et al. PLoS ONE, DOI://10.1371/journal.pone.0155420 (2016)
Structural Determinants of Misfolding in Multidomain Proteins Pengfei Tian and Robert B. Best PLoS Computational Biology, 10.1371/journal.pcbi.1004933 (2016)
Delineation of Polypharmacology across the Human Structural Kinome Using a Functional Site Interaction Fingerprint Approach Zhao Z, Xie L, Xie L, Bourne PE J. Med. Chem., DOI://10.1021/acs.jmedchem.5b02041 (2016)
Distinct epigenetic features of differentiation-regulated replication origins Smith, OK; Kim, R; Fu, H et al. Epigenetics Chromatin, DOI://10.1186/s13072-016-0067-3 (2016)
Learned Value Shapes Responses to Objects in Frontal and Ventral Stream Networks in Macaque Monkeys Kaskan, PM; Costa, VD; Eaton, HP et al. Cereb. Cortex, DOI://10.1093/cercor/bhw113 (2016)
PA-seq for Global Identification of RNA Polyadenylation Sites of Kaposi's Sarcoma-Associated Herpesvirus Transcripts Ni T, Majerciak V, Zheng ZM, Zhu J Curr Protoc Microbiol, DOI://10.1002/cpmc.1 (2016)
Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G Stewart-Jones, GB; Soto, C; Lemmin, T et al. Cell, DOI://10.1016/j.cell.2016.04.010 (2016)
CLIP-seq to Identify KSHV ORF57-Binding RNA in Host B Cells Ma Y, Liu P, Majerciak V, Zhu J, Zheng ZM Curr Protoc Microbiol, DOI://10.1002/cpmc.3 (2016)
Sparse signal representation in digital and biological system Matthew Guay PhD Thesis, University of Maryland (2016)
Genome Sequence of the Banana Plant Growth-Promoting Rhizobacterium Pseudomonas fluorescens PS006 Gamez, RM; Rodríguez, F; Ramírez, S et al. Genome Announc, DOI://10.1128/genomeA.00329-16 (2016)

Identification of an Immunogenic Subset of Metastatic Uveal Melanoma Rothermel, LD; Sabesan, AC; Stephens, DJ et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-15-2294 (2016)
Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways Psaila, B; Barkas, N; Iskander, D et al. Genome Biol., DOI://10.1186/s13059-016-0939-7 (2016)
Regional Variations in Brain Gyrification Are Associated with General Cognitive Ability in Humans Michael D. Gregory, J. Shane Kippenhan, Dwight Dickinson, Jessica Carrasco, Venkata S. Mattay, Daniel R. Weinberger, Karen F. Berman Current Biology, doi:10.1016/j.cub.2016.03.021 (2016)
A Common Polymorphism in HIBCH Influences Methylmalonic Acid Concentrations in Blood Independently of Cobalamin Anne M. Molloy, Faith Pangilinan , et al. Am. J. Hum. Genet., DOI:10.1016/j.ajhg.2016.03.005 show (2016)
Arginine kinase from Myzostoma cirriferum, a basal member of annelids Daichi Yano, Sayo Mimura, Kouji Uda, Tomohiko Suzuki Comparative Biochemistry and Physiology Part B: Biochemistry, doi:10.1016/j.cbpb.2016.04.004 (2016)
TNF-α modulates genome-wide redistribution of ΔNp63α/TAp73 and NF-κB cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer Si, H; Lu, H; Yang, X et al. Oncogene, DOI://10.1038/onc.2016.112 (2016)
DR-TAMAS: Diffeomorphic Registration for Tensor Accurate Alignment of Anatomical Structures Irfanoglu, MO; Nayak, A; Jenkins, J et al. Neuroimage, DOI://10.1016/j.neuroimage.2016.02.066 (2016)
Challenges in studying the structures of metal- amyloid oligomers related to type 2 diabetes, parkinson's disease, and alzheimer's disease Vered Wineman-Fisher, Daniel Nir Bloch, Yifat Miller Coordination Chemistry Reviews, doi:10.1016/j.ccr.2016.04.010 (2016)
Using cryo-EM to map small ligands on dynamic metabolic enzymes: Studies with glutamate dehydrogenase Mario J. Borgnia, Soojay Banerjee, Alan Merk, Doreen Matthies, Alberto Bartesaghi, Prashant Rao, Jason Pierson, Lesley A. Earl, Veronica Falconieri, Sriram Subramaniam, and Jacqueline L. S. Milne Molecular Pharmacology, doi: 10.1124/mol.116.103382 (2016)
Membrane-associated Ras dimers are isoform-specific: K-Ras dimers differ from H-Ras dimers Hyunbum Jang, Serena Muratcioglu, Attila Gursoy, Ozlem Keskin, Ruth Nussinov Biochemical J., DOI: 10.1042/BCJ20160031 (2016)
Plasmid-Based Materials as Multiplex Quality Controls and Calibrators for Clinical Next-Generation Sequencing Assays David J. Sims, Robin D. Harrington, Eric C. Polley, Thomas D. Forbes, Michele G. Mehaffey, Paul M. McGregor III, Corinne E. Camalier, Kneshay N. Harper, Courtney H. Bouk, Biswajit Das, Barbara A. Conley, James H. Doroshow, P. Mickey Williams, Chih-Jian Lih J. Molecular Diagnostics, doi:10.1016/j.jmoldx.2015.11.008 (2016)
High-level expression of Proteinase K from Tritirachium album Limber in Pichia pastoris using multi-copy expression strains Yang, H; Zhai, C; Yu, X et al. Protein Expr. Purif., DOI://10.1016/j.pep.2016.02.006 (2016)

Laminopathies disrupt epigenomic developmental programs and cell fate Perovanovic, J; Dell'Orso, S; Gnochi, VF et al. Sci Transl Med, DOI://10.1126/scitranslmed.aad4991 (2016)
Structure-based designing of sordarin derivative as potential fungicide with pan-fungal activity Biprashekhar Chakrabortya, Nikunjkumar Vinodray Sejpalb, Pavan V. Payghana, Nanda Ghoshala, Jayati Sengupta J. Mol. Graph. Model. , doi:10.1016/j.jmgm.2016.03.013 (2016)
BIG: A large-scale data integration tool for renal physiology Yue Zhao, Chin-Rang Yang, Viswanathan Raghuram, Jaya Parulekar, Mark A. Knepper Am. J. Physiol. Renal Physiol. , DOI: 10.1152/ajprenal.00249.2016 (2016)
Tracking brain arousal fluctuations with fMRI Chang, C; Leopold, DA; Schölvinck, ML et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1520613113 (2016)
The Ancient Evolutionary History of Polyomaviruses Buck, CB; Van Doorslaer, K; Peretti, A et al. PLoS Pathog., DOI://10.1371/journal.ppat.1005574 (2016)
An Integrated Genome-Wide Systems Genetics Screen for Breast Cancer Metastasis Susceptibility Genes Ling Bai, Howard H. Yang, Ying Hu, Anjali Shukla, Ngoc-Han Ha, Anthony Doran, Farhoud Faraji, Natalie Goldberger, Maxwell P. Lee, Thomas Keane, Kent W. Hunter PLoS Genetics, doi://10.1371/journal.pgen.1005989 (2016)

Biallelic BRCA2 Mutations Shape the Somatic Mutational Landscape of Aggressive Prostate Tumors Brennan Decker, Danielle M. Karyadi, Brian W. Davis, Eric Karlins, Lori S. Tillmans, Janet L. Stanford, Stephen N. Thibodeau, Elaine A. Ostrander Am. J. Hum. Genet. , doi:10.1016/j.ajhg.2016.03.003 (2016)
Characterization of influenza vaccine hemagglutinin complexes by cryo-electron microscopy and image analyses reveals structural polymorphisms Dustin M. McCraw, John R. Gallagher and Audray K. Harris Clin. Vaccine Immunol. , oi:10.1128/CVI.00085-16 (2016)
Adaptation of pancreatic islet cyto-architecture during development Deborah A Striegel, Manami Hara and Vipul Periwal Physical Biology, doi://10.1088/1478-3975/13/2/025004 (2016)
Low-frequency and common genetic variation in ischemic stroke R Malik, M Traylor et al. Neurology, doi://10.1212/WNL.0000000000002528 (2016)
Comparison of normalization and differential expression analyses using RNA-Seq data from 726 individual Drosophila melanogaster Lin Y, Golovnina K, Chen ZX, Lee HN, Negron YL, Sultana H, Oliver B, Harbison ST BMC Genomics, doi: 10.1186/s12864-015-2353-z (2016)
Purine (N)-Methanocarba Nucleoside Derivatives Lacking an Exocyclic Amine as Selective A3 Adenosine Receptor Agonists Tosh, DK; Ciancetta, A; Warnick, E et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.5b01998 (2016)

Novel Analogues of (R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity Zou, MF; Keck, TM; Kumar, V et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.5b01612 (2016)
Fatty Acid Oxidation is Impaired in An Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease Menezes LF, Lin CC, Zhou F, Germino GG EBioMedicine, 2352-3964 (2016)
Temperature-Dependent Conformational Properties of Human Neuronal Calcium Sensor-1 Protein Revealed by All-Atom Simulations Zhu Y, Ma B, Qi R, Nussinov R, Zhang Q J Phys Chem B, DOI://10.1021/acs.jpcb.5b12299 (2016)
Linear Discriminant Analysis Achieves High Classification Accuracy for the BOLD fMRI Response to Naturalistic Movie Stimuli Mandelkow, H; de Zwart, JA; Duyn, JH; Front Hum Neurosci, DOI://10.3389/fnhum.2016.00128 (2016)
Evidence for N-Terminal Myristoylation of Tetrahymena Arginine Kinase Using Peptide Mass Fingerprinting Analysis Shou Motomura, Tomohiko Suzuki Protein J. , doi://10.1007/s10930-016-9663-0 (2016)
Axial superresolution via multiangle TIRF microscopy with sequential imaging and photobleaching Yan Fu, Peter W. Winter, Raul Rojas, Victor Wang, Matthew McAuliffe, and George H. Patterson PNAS, doi: 10.1073/pnas.1516715113 (2016)

Novel Analogues of (R)-5-(Methylamino)-5, 6-dihydro-4 H-imidazo [4, 5, 1-ij] quinolin-2 (1 H)-one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity Mu-Fa Zou, Thomas M. Keck, Vivek Kumar, Prashant Donthamsetti, Mayako Michino, Caitlin Burzynski, Catherine Schweppe, Alessandro Bonifazi, R. Benjamin Free, David R. Sibley, Aaron Janowsky, Lei Shi, Jonathan A. Javitch, and Amy Hauck Newman J. Med. Chem. , DOI: 10.1021/acs.jmedchem.5b01612 (2016)
Repertoires of Spike Avalanches Are Modulated by Behavior and Novelty Tiago L. Ribeiro, Sidarta Ribeiro and Mauro Copelli Frontiers in Neural Circuits, doi:///10.3389/fncir.2016.00016 (2016)
Characterization of the platelet transcriptome by RNA sequencing in patients with acute myocardial infarction Eicher, JD; Wakabayashi, Y; Vitseva, O et al. Platelets, DOI://10.3109/09537104.2015.1083543 (2016)
Distinguishing highly similar gene isoforms with a clustering-based bioinformatics analysis of PacBio single-molecule long reads Liang, M; Raley, C; Zheng, X et al. BioData Min, DOI://10.1186/s13040-016-0090-8 (2016)
The Human Physiome: how standards, software and innovative service infrastructures are providing the building blocks to make it achievable Nickerson, D; Atalag, K; de Bono, B et al. Interface Focus, DOI://10.1098/rsfs.2015.0103 (2016)
Structure and function of the AAA+ ATPase p97/Cdc48p Xia D, Tang WK, Ye Y Gene, DOI://10.1016/j.gene.2016.02.042 (2016)

Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome Falcone, EL; Abusleme, L; Swamydas, M et al. Microbiome, DOI://10.1186/s40168-016-0159-0 (2016)
MultiDimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A Report from the Center for Cancer Research Wendy Chang, Andrew Brohl, Rajesh Patidar, Sivasish Sindiri, Jack F. Shern, Jun S. Wei, Young K. Song, Marielle E Yohe, Berkley E. Gryder, Shile Zhang, Kathleen A Calzone, Nityashree Shivaprasad, Xinyu Wen, Thomas Badgett, Markku Miettinen, Kip R Hartman, James C League-Pascual, Toby Trahair, Brigitte C. Widemann, Melinda S. Merchant, Rosandra N Kaplan, Jimmy C Lin, and Javed Khan Clinical Cancer Research, doi: 10.1158/1078-0432.CCR-15-2717 (2016)
Erratum: The evolutionary turnover of recombination hot spots contributes to speciation in mice Smagulova, F; Brick, K; Pu, Y; Camerini-Otero, RD; Petukhova, GV; Genes Dev., DOI://10.1101/gad.280677.116 (2016)
Aberrant intrinsic functional connectivity within and between corticostriatal and temporal-parietal networks in adults and youth with bipolar disorder Stoddard, J; Gotts, SJ; Brotman, MA et al. Psychol Med, DOI://10.1017/S0033291716000143 (2016)
Cajal bodies are linked to genome conformation Qiuyan Wang, Iain A. Sawyer, Myong-Hee Sung, David Sturgill, Sergey P. Shevtsov, Gianluca Pegoraro, Ofir Hakim, Songjoon Baek, Gordon L. Hager & Miroslav Dundr Nature Communications, doi:10.1038/ncomms10966 (2016)
Cryo-electron Microscopy Structures of Chimeric Hemagglutinin Displayed on a Universal Influenza Vaccine Candidate Erin E. H. Tran, Kira A. Podolsky, Alberto Bartesaghi, Oleg Kuybeda, Giovanna Grandinetti, Teddy John Wohlbold, Gene S. Tan, Raffael Nachbagauer, Peter Palese, Florian Krammer, Sriram Subramaniam mBio, doi: 10.1128/mBio.00257-16 (2016)

Subtle in-scanner motion biases automated measurement of brain anatomy from in vivo MRI Aaron Alexander-Bloch, Liv Clasen, Michael Stockman, Lisa Ronan, Francois Lalonde, Jay Giedd and Armin Raznahan Human Brain Mapping, DOI: 10.1002/hbm.23180 (2016)
Detection of benign prostatic hyperplasia nodules in T2W MR images using fuzzy decision forest Nathan Lay ; Sabrina Freeman ; Baris Turkbey ; Ronald Summers SPIE Proceedings, doi:10.1117/12.2217906 (2016)
2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition Soojay Banerjee, Alberto Bartesaghi, Alan Merk, Prashant Rao, Stacie L. Bulfer, Yongzhao Yan, Neal Green, Barbara Mroczkowski, R. Jeffrey Neitz, Peter Wipf, Veronica Falconieri, Raymond J. Deshaies, Jacqueline L. S. Milne, Donna Huryn, Michelle Arkin, Sriram Subramaniam Science, DOI: 10.1126/science.aad7974 (2016)
Design and synthesis of small molecule-sulfotyrosine mimetics that inhibit HIV-1 entry Dogo-Isonagie, C; Lee, SL; Lohith, K et al. Bioorg. Med. Chem., DOI://10.1016/j.bmc.2016.02.044 (2016)
Detection and Whole-Genome Sequencing of Carbapenemase-Producing Aeromonas hydrophila Isolates from Routine Perirectal Surveillance Culture Hughes, HY; Conlan, SP; Lau, AF et al. J. Clin. Microbiol., DOI://10.1128/JCM.03229-15 (2016)
Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers Robles, AI; Traverso, G; Zhang, M et al. Gastroenterology, DOI://10.1053/j.gastro.2015.12.036 (2016)
Emerging Functions of Natural IgM and Its Fc Receptor FCMR in Immune Homeostasis Wang, H; Coligan, JE; Morse, HC; Front Immunol, DOI://10.3389/fimmu.2016.00099 (2016)
caOmicsV: an R package for visualizing multidimensional cancer genomic data Zhang H, Meltzer PS, Davis SR BMC Bioinformatics, DOI://10.1186/s12859-016-0989-6 (2016)
A molecular threshold for effector CD8(+) T cell differentiation controlled by transcription factors Blimp-1 and T-bet Xin, A; Masson, F; Liao, Y et al. Nat. Immunol., DOI://10.1038/ni.3410 (2016)
Brain-Derived Neurotrophic Factor Val66Met Polymorphism Affects the Relationship Between an Anxiety-Related Personality Trait and Resting Regional Cerebral Blood Flow Wei, SM; Eisenberg, DP; Nabel, KG et al. Cereb. Cortex, DOI://10.1093/cercor/bhw072 (2016)
Redox-induced activation of the proton pump in the respiratory complex I Vivek Sharma, Galina Belevich, Ana P. Gamiz-Hernandez, Tomasz Ròg, Ilpo Vattulainen, Marina L. Verkhovskaya Mårten Wikström, Gerhard Hummer, and Ville R. I. Kaila PNAS, doi://10.1073/pnas.1503761112 (2016)
High-level expression and characterization of a novel serine protease in Pichia pastoris by multi-copy integration Min Shu, Wei Shen, Shihui Yang , Xiaojuan Wang , Fei Wang , Yaping Wang , Lixin Ma Enzyme and Microbioal Technology, doi:10.1016/j.enzmictec.2016.06.007 (2016)

NMDA Receptors Multiplicatively Scale Visual Signals and Enhance Directional Motion Discrimination in Retinal Ganglion Cells Poleg-Polsky A, Diamond JS Neuron, DOI://10.1016/j.neuron.2016.02.013 (2016)
MEGSA: A Powerful and Flexible Framework for Analyzing Mutual Exclusivity of Tumor Mutations Xing Hua, Paula L. Hyland, Jing Huang, Lei Song, Bin Zhu, Neil E. Caporaso, Maria Teresa Landi, Nilanjan Chatterjee, and Jianxin Shi Am J. Hum. Genet. , doi://10.1016/j.ajhg.2015.12.021 (2016)
Characterizing the Covalent Targets of a Small Molecule Inhibitor of the Lysine Acetyltransferase P300 Shrimp JH, Sorum AW, Garlick JM, Guasch L, Nicklaus MC, Meier JL ACS Med Chem Lett, DOI://10.1021/acsmedchemlett.5b00385 (2016)
Plasticity of Sensorimotor Networks: Multiple Overlapping Mechanisms Buch, ER; Liew, SL; Cohen, LG; Neuroscientist, DOI://10.1177/1073858416638641 (2016)
Critical Nucleus Structure and Aggregation Mechanism of the C-terminal Fragment of Copper-Zinc Superoxide Dismutase Protein Zou Y, Sun Y, Zhu Y, Ma B, Nussinov R, Zhang Q ACS Chem Neurosci, DOI://10.1021/acschemneuro.5b00242 (2016)
Seeking Optimal Region-Of-Interest (ROI) Single-Value Summary Measures for fMRI Studies in Imaging Genetics Tong, Y; Chen, Q; Nichols, TE et al. PLoS ONE, DOI://10.1371/journal.pone.0151391 (2016)

Microscopic interpretation of folding φ-values using the transition path ensemble Robert B. Best and Gerhard Hummer PNAS, doi: 10.1073/pnas.1520864113 (2016)
Structural insights of a PI3K/mTOR dual inhibitor with the morpholino-triazine scaffold Takako Takeda, Yanli Wang , Stephen H. Bryant J. Computer-Aided Molecular Design, doi://10.1007/s10822-016-9905-4 (2016)
Modulation of Folding Internal Friction by Local and Global Barrier Heights Wenwei Zheng, David de Sancho, and Robert B. Best J. Phys. Chem. Letters, DOI: 10.1021/acs.jpclett.6b00329 (2016)
The ISW1 and CHD1 ATP-dependent chromatin remodelers compete to set nucleosome spacing in vivo Josefina Ocampo, Razvan V. Chereji, Peter R. Eriksson and David J. Clark Nucleic Acids Research, doi://10.1093/nar/gkw068 (2016)
Biointeractions of ultrasmall glutathione-coated gold nanoparticles: effect of small size variations Alioscka A. Sousa, Sergio A. Hassan, Luiza L. Knittel, Andrea Balbo, Maria A. Aronova, Patrick H. Brown, Peter Schuck and Richard D. Leapman Nanoscale, DOI: 10.1039/C5NR07642K (2016)
The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes Rinschen, MM; Bharill, P; Wu, X et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddw016 (2016)

Mucolipidosis types II and III and non-syndromic stuttering are associated with different variants in the same genes Raza, MH; Domingues, CE; Webster, R et al. Eur. J. Hum. Genet., DOI://10.1038/ejhg.2015.154 (2016)
The Use of Minimal RNA Toeholds to Trigger the Activation of Multiple Functionalities Afonin, KA; Viard, M; Tedbury, P et al. Nano Lett., DOI://10.1021/acs.nanolett.5b04676 (2016)
Deep Convolutional Neural Networks for Computer-Aided Detection: CNN Architectures, Dataset Characteristics and Transfer Learning Hoo-Chang Shin Holger R. Roth ; Mingchen Gao ; Le Lu ; Ziyue Xu ; Isabella Nogues ; Jianhua Yao ; Daniel Mollura ; Ronald M. Summers IEEE Transactions on Medical Imaging, OI 10.1109/TMI.2016.2528162 (2016)
Preterm birth and air pollution: Critical windows of exposure for women with asthma Pauline Mendola, Maeve Wallace, Beom Seuk Hwang, Danping Liu, Candace Robledo, Tuija Mӓnnistö, Rajeshwari Sundaram, Seth Sherman, Qi Ying, Katherine L. Grantz J. Allergy Clin. Immunology, doi:10.1016/j.jaci.2015.12.1309 (2016)
Necdin is a breast cancer metastasis suppressor that regulates the transcription of c-Myc Minnkyong Lee, Sarah M. Beggs, Derek Gildea, Sujata Bupp, Jens Lichtenberg, Niraj S. Trivedi, NISC Comparative Sequencing Program, Ying Hu, David M. Bodine, and Nigel P.S. Crawford1 Oncotarget, doi: 10.18632/oncotarget.5230 (2016)
Genome-wide footprinting: ready for prime time? Myong-Hee Sung, Songjoon Baek & Gordon L Hager Nature Methods, doi:10.1038/nmeth.3766 (2016)

A Comparison of Methods to Reweight from Classical Molecular Simulations to QM/MM Potentials Eric Christopher Dybeck, Gerhard König, Bernard R. Brooks, and Michael R. Shirts J. Chem. Theory. Comput, DOI: 10.1021/acs.jctc.5b01188 (2016)
Multistrand Structure Prediction of Nucleic Acid Assemblies and Design of RNA Switches Eckart Bindewald, Kirill A. Afonin, Mathias Viard, Paul Zakrevsky, Taejin Kim, and Bruce A. Shapiro Nano Letters, DOI: 10.1021/acs.nanolett.5b04651 (2016)
Understanding the Mechanism of the Hydrogen Abstraction from Arachidonic Acid Catalyzed by the Human Enzyme 15-Lipoxygenase-2. A Quantum Mechanics/Molecular Mechanics Free Energy Simulation Reynier Suardiaz, Pablo Garcia Jambrina, Laura Masgrau, Ángels Gonzàlez-Lafont, Edina Rosta, and Josè M. Lluch J. Chem. Theory. Comput, DOI: 10.1021/acs.jctc.5b01236 (2016)
Impact of time-of-day on brain morphometric measures derived from T₁-weighted magnetic resonance imaging Aaron Trefler, Neda Sadeghi, Adam G. Thomas, Carlo Pierpaoli, Chris I. Baker, Cibu Thomas Neuroimage, doi:10.1016/j.neuroimage.2016.02.034 (2016)
Production of small cysteine-rich effector proteins in Escherichia coli for structural and functional studies Xiaoxiao Zhang, Neal Nguyen, Susan Breen, Megan A. Outram, Peter N. Dodds, Bostjan Kobe, Peter S. Solomon and Simon J. Williams Molecular Plant Pathology, DOI: 10.1111/mpp.12385 (2016)
Deubiquitylation of protein cargo is not an essential step in exosome formation Alyssa R. Huebner, Lei Cheng, Poorichaya Somparn, Mark A. Knepper, Robert A. Fenton and Trairak Pisitkun Molecular and Cellular Proteomics, doi: 10.1074/mcp.M115.054965 (2016)

Enhancer of Rudimentary Cooperates with Conserved RNA-Processing Factors to Promote Meiotic mRNA Decay and Facultative Heterochromatin Assembly Sugiyama, T; Thillainadesan, G; Chalamcharla, VR et al. Mol. Cell, DOI://10.1016/j.molcel.2016.01.029 (2016)
Mechanism of Protein Molecule Isolation by IR Laser Ablation of Droplet Beam Kensuke Komatsu, Takuya Nirasawa, Mariko Hoshino-Nagasaka, and Jun-ya Kohno J. Phys. Chem. A, DOI: 10.1021/acs.jpca.5b10873 (2016)
A Helitron transposon reconstructed from bats reveals a novel mechanism of genome shuffling in eukaryotes Grabundzija, I; Messing, SA; Thomas, J et al. Nat Commun, DOI://10.1038/ncomms10716 (2016)
A genome landscape of SRSF3-regulated splicing events and gene expression in human osteosarcoma U2OS cells Ajiro M, Jia R, Yang Y, Zhu J, Zheng ZM Nucleic Acids Res., DOI://10.1093/nar/gkv1500 (2016)
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients Alena Gros, Maria R Parkhurst, Eric Tran, Anna Pasetto, Paul F Robbins, Sadia Ilyas, Todd D Prickett, Jared J Gartner, Jessica S Crystal, Ilana M Roberts, Kasia Trebska-McGowan, John R Wunderlich, James C Yang & Steven A Rosenberg Nature Medicine, doi:10.1038/nm.4051 (2016)
Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts Liang Ma, Zehua Chen, Da Wei Huang et. al. Nature Communications, doi:10.1038/ncomms10740 (2016)

Gene-Based Association Analysis for Censored Traits Via Fixed Effect Functional Regressions. Fan R, Wang Y, Yan Q, Ding Y, Weeks DE, Lu Z, Ren H, Cook RJ, Xiong M, Swaroop A, Chew EY, Chen W Genet Epidemiol. , doi: 10.1002/gepi.21947 (2016)
Finite sample pointwise confidence intervals for a survival distribution with right-censored data Michael P. Fay and Erica H. Brittain Statistics in Medicine, DOI: 10.1002/sim.6905 (2016)
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept Franke, B; Stein, JL; Ripke, S et al. Nat. Neurosci., DOI://10.1038/nn.4228 (2016)
High-throughput single-molecule screen for small-molecule perturbation of splicing and transcription kinetics Day CR, Chen H, Coulon A, Meier JL, Larson DR, Methods, DOI://10.1016/j.ymeth.2015.11.025 (2016)
Resolving the Complexity of Human Skin Metagenomes Using Single-Molecule Sequencing Yu-Chih Tsai, Sean Conlan, Clayton Deming, NISC Comparative Sequencing Program, Julia A. Segre, Heidi H. Kong Jonas Korlach, and Julia Oh mBio, doi: 10.1128/mBio.01948-15 (2016)
Recessive mutations of TMC1 associated with moderate to severe hearing loss Ayesha Imtiaz , Azra Maqsood , Atteeq U. Rehman, Robert J. Morell, Jeffrey R. Holt, Thomas B. Friedman, Sadaf Naz Neurogenetics, DOI 10.1007/s10048-016-0477-1 (2016)

Light-regulated Molecular Trafficking in a Synthetic Water-soluble Host Jesús del Barrio, Sean T. J. Ryan, Pablo G. Jambrina, Edina Rosta, and Oren A Scherman JACS, DOI: 10.1021/jacs.5b11642 (2016)
Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating Doreen Matthies, Olivier Dalmas, Mario J. Borgnia, Pawel K. Dominik, Alan Merk, Prashant Rao, Bharat G. Reddy, Shahidul Islam, Alberto Bartesaghi, Eduardo Perozo, Sriram Subramaniam Cell, doi:10.1016/j.cell.2015.12.055 (2016)
Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin Chanhyung Bae, Claudio Anselmi, Jeet Kalia, Andres Jara-Oseguera, Charles D Schwieters, Dmitriy Krepkiy ,Chul Won Lee, Eun-Hee Kim, Jae Il Kim, Josè D Faraldo-Gòmez and Kenton J Swartz eLife, DOI: http://dx.doi.org/10.7554/eLife.11273 (2016)
Self-aggregation and coaggregation of the p53 core fragment with its aggregation gatekeeper variant Jiangtao Lei , Ruxi Qi , Guanghong Wei , Ruth Nussinov and Buyong Ma Phys. Chem. Chem. Phys., DOI: 10.1039/C5CP06538K (2016)
Cutting Edge: Expression of IRF8 in Gastric Epithelial Cells Confers Protective Innate Immunity against Helicobacter pylori Infection Yan, M; Wang, H; Sun, J et al. J. Immunol., DOI://10.4049/jimmunol.1500766 (2016)
Genome-Wide Chromatin Landscape Transitions Identify Novel Pathways in Early Commitment to Osteoblast Differentiation Thompson B, Varticovski L, Baek S, Hager GL PLoS ONE, DOI://10.1371/journal.pone.0148619 (2016)

Vibratory Urticaria Associated with a Missense Variant in ADGRE2 Boyden, SE; Desai, A; Cruse, G et al. N. Engl. J. Med., DOI://10.1056/NEJMoa1500611 (2016)
Drug repurposing to target Ebola virus replication and virulence using structural systems pharmacology Zhao Z, Martin C, Fan R, Bourne PE, Xie L BMC Bioinformatics, DOI://10.1186/s12859-016-0941-9 (2016)
Identifying subgroups of enhanced predictive accuracy from longitudinal biomarker data by using tree-based approaches: applications to fetal growth Jared C. Foster, Danping Liu, Paul S. Albert and Aiyi Liu Journal of the Royal Statistical Society: Series A (Statisti, 10.1111/rssa.12182 (2016)
How Does Hyperphopsphorylation Promote Tau Aggregation and Modulate Filament Structure and Stability? Liang Xu, Jie Zheng, Martin Margittai, Ruth Nussinov, and Buyong Ma ACS Chemical Neuroscience, 10.1021/acschemneuro.5b00294 (2016)
In vivo tissue has non-linear rheological behavior distinct from 3D biomimetic hydrogels, as determined by AMOTIV microscopy Blehm BH, Devine A, Staunton JR, Tanner K Biomaterials, DOI://10.1016/j.biomaterials.2015.12.019 (2016)
Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium van den Berg, SM; de Moor, MH; Verweij, KJ et al. Behav. Genet., DOI://10.1007/s10519-015-9735-5 (2016)
Draft Genome Sequence of a Klebsiella pneumoniae Carbapenemase-Positive Sequence Type 111 Pseudomonas aeruginosa Strain Dotson GA, , Dekker JP, Palmore TN, Segre JA, Conlan S Genome Announc, DOI://10.1128/genomeA.01663-15 (2016)
The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1 Dell'Orso, S; Wang, AH; Shih, HY et al. Cell Rep, 2211-1247 (2016)
Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice Davies, B; Hatton, E; Altemose, N et al. Nature, DOI://10.1038/nature16931 (2016)
r2VIM: A new variable selection method for random forests in genome-wide association studies Silke Szymczak, Emily Holzinger, Abhijit Dasgupta, James D. Malley, Anne M. Molloy, James L. Mills, Lawrence C. Brody, Dwight Stambolian and Joan E. Bailey-Wilson BioData Mining, 10.1186/s13040-016-0087-3 (2016)
Identification of Microorganisms by High Resolution Tandem Mass Spectrometry with Accurate Statistical Significance Gelio Alves, Guanghui Wang, Aleksey Y. Ogurtsov, Steven K. Drake, Marjan Gucek, Anthony F. Suffredini, David B. Sacks, Yi-Kuo Yu J Am Soc Mass Spectrom 27:194-210, 10.1007/s13361-015-1271-2 (2016)
CircInteractome: A web tool for exploring circular RNAs and their interacting proteins and microRNAs Dudekula, DB; Panda, AC; Grammatikakis, I; De, S; Abdelmohsen, K; Gorospe, M; RNA Biol, DOI://10.1080/15476286.2015.1128065 (2016)

Somatic mutational landscape of AML with inv(16) or t(8;21) identifies patterns of clonal evolution in relapse leukemia Sood, R; Hansen, NF; Donovan, FX et al. Leukemia, DOI://10.1038/leu.2015.141 (2016)
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function Pattaro, C; Teumer, A; Gorski, M et al. Nat Commun, DOI://10.1038/ncomms10023 (2016)
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels Kilpeläinen, TO; Carli, JF; Skowronski, AA et al. Nat Commun, DOI://10.1038/ncomms10494 (2016)
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk Lu, Y; Day, FR; Gustafsson, S et al. Nat Commun, DOI://10.1038/ncomms10495 (2016)
Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium Ma, Y; Follis, JL; Smith, CE et al. Am. J. Clin. Nutr., DOI://10.3945/ajcn.115.112987 (2016)
Is the MC1R variant p. R160W associated with Parkinson's? Lubbe, SJ; Escott-Price, V; Brice, A et al. Ann. Neurol., DOI://10.1002/ana.24527 (2016)

Comparison of the Conformations of KRAS Isoforms, K-Ras4A and K-Ras4B, Points to Similarities and Significant Differences Mayukh Chakrabarti, Hyunbum Jang, and Ruth Nussinov J. Phys. Chem. B, DOI: 10.1021/acs.jpcb.5b11110 (2016)
Risk of End-stage Renal Disease in Patients with Lupus Nephritis, 1970 to 2015 A systematic review and Bayesian meta-analysis Maria G. Tektonidou, Abhijit Dasgupta and Michael M. Ward Arthritis and Rheumatology, DOI: 10.1002/art.39594 (2016)
Coupling of the Non-Amyloid-Component (NAC) Domain and the KTK(E/Q)GV Repeats Stabilize the α-Synuclein Fibrils Liang Xu, Ruth Nussinov, Buyong Ma Eur. J. Med. Chem. , doi:10.1016/j.ejmech.2016.01.044 (2016)
Novel nucleosomal particles containing core histones and linker DNA but no histone H1 Cole, HA; Cui, F; Ocampo, J et al. Nucleic Acids Res., DOI://10.1093/nar/gkv943 (2016)
The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl Dine, JL; O'Sullivan, CC; Voeller, D et al. Breast Cancer Res. Treat., DOI://10.1007/s10549-015-3673-z (2016)
Epigenetic regulation of hematopoiesis by DNA methylation Gore, AV; Athans, B; Iben, JR et al. Elife, DOI://10.7554/eLife.11813 (2016)

Role of the D1-D2 Linker of Human VCP/p97 in the Asymmetry and ATPase Activity of the D1-domain Tang WK, Xia D Sci Rep, DOI://10.1038/srep20037 (2016)
Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study Liping Hou, Urs Heilbronner et al. Lancet, doi:10.1016/S0140-6736(16)00143-4 (2016)
Autosomal-Recessive Hearing Impairment due to Rare Missense Variants within S1PR2 Regie Lyn P. Santos-Cortez, Rabia Faridi, Atteeq U. Rehman et al. American Journal of Human Genetics, doi://10.1016/j.ajhg.2015.12.004 (2016)
Post-transcriptional Control of Tumor Cell Autonomous Metastatic Potential by CCR4-NOT Deadenylase CNOT7 Faraji, F; Hu, Y; Yang, HH et al. PLoS Genet., DOI://10.1371/journal.pgen.1005820 (2016)
Nanopore Sequencing as a Rapidly Deployable Ebola Outbreak Tool Thomas Hoenen, Allison Groseth, Kyle Rosenke et al. Emerging Infectious Diseases, doi: 10.3201/eid2202.151796. (2016)
Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment Zhong, C; Cui, K; Wilhelm, C et al. Nat. Immunol., DOI://10.1038/ni.3318 (2016)

Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for Cellular Therapy Sukumar, M; Liu, J; Mehta, GU et al. Cell Metab., DOI://10.1016/j.cmet.2015.11.002 (2016)
Reliability of 7T (1) H-MRS measured human prefrontal cortex glutamate, glutamine, and glutathione signals using an adapted echo time optimized PRESS sequence: A between- and within-sessions investigation Lally, N; An, L; Banerjee, D et al. J Magn Reson Imaging, DOI://10.1002/jmri.24970 (2016)
A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration de Vries, PS; Chasman, DI; Sabater-Lleal, M et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddv454 (2016)
Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes Lorenzi, H; Khan, A; Behnke, MS et al. Nat Commun, DOI://10.1038/ncomms10147 (2016)
PubChem Substance and Compound databases Kim, S; Thiessen, PA; Bolton, EE et al. Nucleic Acids Res., DOI://10.1093/nar/gkv951 (2016)
SBR-Blood: systems biology repository for hematopoietic cells Lichtenberg, J; Heuston, EF; Mishra, T; Keller, CA; Hardison, RC; Bodine, DM; Nucleic Acids Res., DOI://10.1093/nar/gkv1263 (2016)

GABBR1 and SLC6A1, Two Genes Involved in Modulation of GABA Synaptic Transmission, Influence Risk for Alcoholism: Results from Three Ethnically Diverse Populations Enoch, MA; Hodgkinson, CA; Shen, PH et al. Alcohol. Clin. Exp. Res., DOI://10.1111/acer.12929 (2016)
SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery Saxena, N; Maio, N; Crooks, DR et al. J. Natl. Cancer Inst., DOI://10.1093/jnci/djv287 (2016)
Evolutionary Dynamics of Influenza A Viruses in US Exhibition Swine Nelson, MI; Wentworth, DE; Das, SR et al. J. Infect. Dis., DOI://10.1093/infdis/jiv399 (2016)

2015 (339 papers)

Bayesian dose-response analysis for epidemiological studies with complex uncertainty in dose estimation Deukwoo Kwon, F. Owen Hoffman, Brian E. Moroz, Steven L. Simon Statistics in Medicine, DOI: 10.1002/sim.6635 (2015)
Augmented trial designs for evaluation of principal surrogates Erin E. Gabriel and Dean Follmann Biostatistics, 10.1093/biostatistics/kxv055 (2015)
Dimerization of the SP1 Region of HIV-1 Gag Induces a Helical Conformation and Association into Helical Bundles: Implications for Particle Assembly Datta, SA; Clark, PK; Fan, L et al. J. Virol., DOI://10.1128/JVI.02061-15 (2015)

Multivariate classification of smokers and nonsmokers using SVM-RFE on structural MRI images Ding X, Yang Y, Stein EA, Ross TJ Hum Brain Mapp, DOI://10.1002/hbm.22956 (2015)
The higher level of complexity of K-Ras4B activation at the membrane Hyunbum Jang, Avik Banerjee, Tanmay S. Chavan, Shaoyong Lu, Jian Zhang, Vadim Gaponenko and Ruth Nussinov FASEB J. , doi: 10.1096/fj.15-279091 (2015)
Mixed group of Rhizobiales microbes in lung and blood of a patient with fatal pulmonary illness Shyh-Ching Lo, Guo-Chiuan Hung, Bing jie Li, Haiyan Lei, Tianwei Li, Kenjiro Nagamine, Shien Tsai, Mark J Zucker, Ludmilla Olesnicky Int J Clin Exp Patho, 8(11), 13834-13852. (2015)
Meta-analysis of Complex Diseases at Gene Level by Generalized Functional Linear Models Ruzong Fan, Yifan Wang, Chi-yang Chiu, Wei Chen, Haobo Ren, Yun Li, Michael Boehnke, Christopher I. Amos, Jason H. Moore, Momiao Xiong Genetics, DOI: 10.1534/genetics.115.180869 (2015)
TET-catalyzed oxidation of intragenic 5-methylcytosine regulates CTCF-dependent alternative splicing Ryan J Marina, David Sturgill, Marc A Bailly, Morgan Thenoz, Garima Varma, Maria F Prigge, Kyster K Nanan, Sanjeev Shukla, Nazmul Haque, Shalini Oberdoerffer EMBO J., DOI 10.15252/embj.201593235 (2015)
RNA Polymerase III Output Is Functionally Linked to tRNA Dimethyl-G26 Modification Arimbasseri, AG; Blewett, NH; Iben, JR et al. PLoS Genet., DOI://10.1371/journal.pgen.1005671 (2015)

Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design Jason Gorman, Cinque Soto, Max M Yang, et al. Nature Structural and Molecular Biology, doi:10.1038/nsmb.3144 (2015)
ADAR2 affects mRNA coding sequence edits with only modest effects on gene expression or splicing in vivo Allissa A. Dillman, Mark R. Cookson & Dagmar Galter RNA Biology, DOI://10.1080/15476286.2015.1110675 (2015)
Controlled DNA double-strand break induction in mice reveals post-damage transcriptome stability Jeongkyu Kim, David Sturgill, Andy D. Tran, David A. Sinclair and Philipp Oberdoerffer Nucleic Acids Research, doi: 10.1093/nar/gkv1482 (2015)
Distributed acoustic cues for caller identity in macaque vocalization Makoto Fukushima, Alex M. Doyle, Matthew P. Mullarkey, Mortimer Mishkin, Bruno B. Averbeck Royal Society Open Science, DOI: 10.1098/rsos.150432 (2015)
Socioeconomic disadvantage and neural development from infancy through early childhood Chin-Lun Hung, G; Hahn, J; Alamiri, B et al. Int J Epidemiol, DOI://10.1093/ije/dyv303 (2015)
Directed and persistent movement arises from mechanochemistry of the ParA/ParB system Hu L, Vecchiarelli AG, Mizuuchi K, Neuman KC, Liu J Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1505147112 (2015)

Assessment of established HDL-C loci for association with HDL-C levels and type 2 diabetes in Pima Indians Anup K. Nair, Paolo Piaggi, Nellie A. McLean, Manmeet Kaur, Sayuko Kobes, William C. Knowler, Clifton Bogardus, Robert L. Hanson, Leslie J. Baier Diabetologia, doi://10.1007/s00125-015-3835-x (2015)
Genome-wide association study identifies African-ancestry specific variants for metabolic syndrome Tekola-Ayele, F; Doumatey, AP; Shriner, D et al. Mol. Genet. Metab., DOI://10.1016/j.ymgme.2015.10.008 (2015)
High-Affinity Interaction of the K-Ras4B Hypervariable Region with the Ras Active Site Tanmay S. Chavan, Hyunbum Jang, Lyuba Khavrutskii, Sherwin J. Abraham, Avik Banerjee, Benjamin C. Freed, Liv Johannessen, Sergey G. Tarasov, Vadim Gaponenko, Ruth Nussinov4, Nadya I. Tarasova Biophys. J. , doi:10.1016/j.bpj.2015.09.034 (2015)
Coupling between histone conformations and DNA geometry in nucleosomes on a microsecond timescale: atomistic insights into nucleosome functions Alexey K. Shaytan, Grigoriy A. Armeev, Alexander Goncearenco, Victor B. Zhurkin, David Landsman, Anna R. Panchenko J. Mol. Biol., doi:10.1016/j.jmb.2015.12.004 (2015)
Evolutionary context for the association of γ-globin, serum uric acid, and hypertension in African Americans Shriner, D; Kumkhaek, C; Doumatey, AP et al. BMC Med. Genet., DOI://10.1186/s12881-015-0249-z (2015)
Drug-Protein Hydrogen Bonds Govern the Inhibition of the ATP Hydrolysis of the Multidrug Transporter P-glycoprotein Eduardo E. Chufan, Khyati Kapoor, Suresh V. Ambudkar Biochemical Pharmacology, doi:10.1016/j.bcp.2015.12.007 (2015)

MYCN controls an alternative RNA splicing program in high-risk metastatic neuroblastoma Shile Zhang, Jun S. Wei1 , Samuel Q. Li , Tom C. Badgett , Young K. Song , Saurabh Agarwal , Cristian Coarfa , Catherine Tolman , Laura Hurd , Hongling Liao , Jianbin He , Xinyu Wen , Zhihui Liu , Carol J. Thiele , Frank Westermann , Shahab Asgharzadeh , Robert C. Seeger , John M. Maris , Jamie M. Guidry Auvil , Malcolm A. Smith , Eric D. Kolaczyk , Jason Shohet , Javed Khan Cancer Letters, doi://10.1016/j.canlet.2015.11.045 (2015)
Multi-modal characterization of rapid anterior hippocampal volume increase associated with aerobic exercise Adam G. Thomas, Andrea Dennis, Nancy B. Rawlings, Charlotte J. Stagg, Lucy Matthews, Martyn Morris, Shannon H. Kolind, Sean Foxley, Mark Jenkinson, Thomas E. Nichols, Helen Dawes, Peter A. Bandettini, Heidi Johansen-Berg NeuroImage, doi:10.1016/j.neuroimage.2015.10.090 (2015)
Allosteric stabilization of the amyloid-β peptide hairpin by the fluctuating N-terminal Liang Xu , Ruth Nussinov and Buyong Ma Chem. Commun., DOI: 10.1039/C5CC08107F (2015)
Intrinsic excitability measures track antiepileptic drug action and uncover increasing/decreasing excitability over the wake/sleep cycle Christian Meisel, Andreas Schulze-Bonhage, Dean Freestone, Mark James Cook, Peter Achermann, Dietmar Plenz PNAS, doi: 10.1073/pnas.1513716112 (2015)
Transcriptional and Chromatin Regulation during Fasting - The Genomic Era Goldstein I, Hager GL Trends Endocrinol. Metab., DOI://10.1016/j.tem.2015.09.005 (2015)
Genome Sequence of the Banana Plant Growth-Promoting Rhizobacterium Bacillus amyloliquefaciens BS006 Rocío M. Gamez, Fernando Rodríguez, Johan F. Bernal, Richa Agarwala, David Landsman, Leonardo Mariño-Ramírez Genome Announc., doi: 10.1128/genomeA.01391-15 (2015)

Evaluation of Genome Wide Association Study Associated Type 2 Diabetes Susceptibility Loci in Sub Saharan Africans Adeyemo, AA; Tekola-Ayele, F; Doumatey, AP et al. Front Genet, DOI://10.3389/fgene.2015.00335 (2015)
HIV Therapeutics and Methods of Making and Using Same Paolo Lusso and Raffaelo Cimbro Patent, United States Patent Application 20150313990 (2015)
NCICT: a computational solution to estimate organ doses for pediatric and adult patients undergoing CT scans Choonsik Lee, Kwang Pyo Kim, Wesley E Bolch, Brian E Moroz and Les Folio J. Radiological Protection, doi:10.1088/0952-4746/35/4/891 (2015)
Reduction of All-Atom Protein Folding Dynamics to One-Dimensional Diffusion Wenwei Zheng and Robert B. Best J. Phys. Chem. , DOI: 10.1021/acs.jpcb.5b09741 (2015)
Transient misfolding dominates multidomain protein folding Alessandro Borgia, Katherine R. Kemplen, Madeleine B. Borgia, Andrea Soranno, Sarah Shammas, Bengt Wunderlich, Daniel Nettels, Robert B. Best, Jane Clarke & Benjamin Schuler Nature Communications, doi:10.1038/ncomms9861 (2015)
Replicate exome-sequencing in a multiple-generation family: improved interpretation of next-generation sequencing data Praveen F. Cherukuri, Valerie Maduro, Karin V. Fuentes-Fajardo, Kevin Lam, David R. Adams, Cynthia J. Tifft, James C. Mullikin, William A. Gahl, Cornelius F. Boerkoel and NISC Comparative Sequencing Program BMC Genomics, doi:10.1186/s12864-015-2107-y (2015)

HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis Michael J. Ombrello, Elaine F. Remmers, Ioanna Tachmazidou et al and the International Childhood Arthritis Genetics (INCHARGE) Consortium PNAS, doi: 10.1073/pnas.1520779112 (2015)
Estimation of interaction effects using pooled biospecimens in a case-control study Michelle R. Danaher, Paul S. Albert, Aninyda Roy and Enrique F. Schisterman Statistics in Medicine, DOI: 10.1002/sim.6798 (2015)
Epstein-Barr virus from Burkitt Lymphoma biopsies from Africa and South America share novel LMP-1 promoter and gene variations Lei H, Li T, Li B, Tsai S, Biggar RJ, Nkrumah F, Neequaye J, Gutierrez M, Epelman S, Mbulaiteye SM, Bhatia K, Lo SC Sci Rep., doi: 10.1038/srep16706 (2015)
A 3D Searchable Database of Transgenic Zebrafish Gal4 and Cre Lines for Functional Neuroanatomy Studies Gregory D. Marquart, Kathryn M. Tabor, Mary Brown, Jennifer L. Strykowski, Gaurav K. Varshney, Matthew C. LaFave, Thomas Mueller, Shawn M. Burgess, Shin-ichi Higashijima and Harold A. Burgess Frontiers in Neural Circuits, doi://10.3389/fncir.2015.00078 (2015)
A Novel MHC-I Surface Targeted for Binding by the MCMV m06 Immunoevasin Revealed by Solution NMR Sgourakis NG, May NA, Boyd LF, Ying J, Bax A, Margulies DH J. Biol. Chem., DOI://10.1074/jbc.M115.689661 (2015)
GTP Binding and Oncogenic Mutations May Attenuate Hypervariable Region (HVR)-Catalytic Domain Interactions in Small GTPase K-Ras4B, Exposing the Effector Binding Site Lu S, Banerjee A, Jang H, Zhang J, Gaponenko V, Nussinov R J. Biol. Chem., DOI://10.1074/jbc.M115.664755 (2015)

Epidermal devices for noninvasive, precise, and continuous mapping of macrovascular and microvascular blood flow Webb, RC; Ma, Y; Krishnan, S et al. Sci Adv, DOI://10.1126/sciadv.1500701 (2015)
Clinical feasibility of using mean apparent propagator (MAP) MRI to characterize brain tissue microstructure Alexandru V. Avram, Joelle E. Sarlls, Alan S. Barnett, Evren Özarslan, Cibu Thomas, M. Okan Irfanoglu, Elizabeth Hutchinson, Carlo Pierpaoli, Peter J. Basser NeuroImage, doi:10.1016/j.neuroimage.2015.11.027 (2015)
Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma Bogen, D; Wei, JS; Azorsa, DO et al. Oncotarget, DOI://10.18632/oncotarget.6208 (2015)
Phenotypic variance explained by local ancestry in admixed African Americans Shriner, D; Bentley, AR; Doumatey, AP et al. Front Genet, DOI://10.3389/fgene.2015.00324 (2015)
Distribution and evolution of the serine/aspartate racemase family in invertebrates Kouji Uda, Keita Abe, Yoko Dehara, Kiriko Mizobata, Natsumi Sogawa, Yuki Akagi, Mai Saigan, Atanas D. Radkov, Luke A. Moe Amino Acids, doi://10.1007/s00726-015-2092-0 (2015)
Selectivity in the Use of Gi/o Proteins Is Determined by the DRF Motif in CXCR6 and Is Cell-Type Specific Satya P. Singh, John F. Foley, Hongwei H. Zhang, Darrell E. Hurt, Jennifer L. Richards, Craig S. Smith, Fang Liao, and Joshua M. Farber Molecular Pharmacology, doi: 10.1124/mol.115.099960 (2015)

The Structural Basis of Actin Organization by Vinculin and Metavinculin Laura Y. Kim, Peter M. Thompson, Hyunna T. Lee, Mihir Pershad, Sharon L. Campbell, Gregory M. Alushin J. Mol. Biol. , doi:10.1016/j.jmb.2015.09.031 (2015)
Analysis of SLC16A11 variants in 12,811 American Indians: genotype-obesity interaction for type 2 diabetes and an association with RNASEK expression Michael Traurig, Robert L. Hanson, Alejandra Marinelarena, Sayuko Kobes, Paolo Piaggi, Shelley Cole, Joanne E. Curran, John Blangero, Harald Göring, Satish Kumar, Robert G. Nelson, Barbara V. Howard, William C. Knowler, Leslie J. Baier and Clifton Bogardus Diabetes, doi: 10.2337/db15-0571 (2015)
In Search of a Cure for Proteostasis-Addicted Cancer: A AAA Target Revealed Xia D, Ye Y Cancer Cell, DOI://10.1016/j.ccell.2015.10.006 (2015)
Genome-wide estimate of the heritability of Multiple System Atrophy M. Federoff, T.R. Price, A. Sailer, S. Scholz, D. Hernandez, A. Nicolas, A.B. Singleton, M. Nalls, H. Houlden Parkinsonism and Related Disorders, doi:10.1016/j.parkreldis.2015.11.005 (2015)
Reprogramming of Polycomb-Mediated Gene Silencing in Embryonic Stem Cells by the miR-290 Family and the Methyltransferase Ash1l Chryssa Kanellopoulou, Timothy Gilpatrick, Gokhul Kilaru, Patrick Burr, Cuong K. Nguyen, Aaron Morawski, Michael J. Lenardo, Stefan A. Muljo Stem Cell Reports, doi:10.1016/j.stemcr.2015.10.001 (2015)
Resting-state functional connectivity and presynaptic monoamine signaling in Alcohol Dependence Zhu X, Dutta N, Helton SG, Schwandt M, Yan J, Hodgkinson CA, Cortes CR, Kerich M, Hall S, Sun H, Phillips M, Momenan R, Lohoff FW Hum Brain Mapp., doi: 10.1002/hbm.22951 (2015)

ColoWeb: a resource for analysis of colocalization of genomic features Kim R, Smith OK, Wong WC, Ryan AM, Ryan MC, Aladjem MI BMC genomics, doi: 10.1186/s12864-015-1345-3. (2015)
Effects of the C-Terminal Tail on the Conformational Dynamics of Human Neuronal Calcium Sensor-1 Protein Zhu, Y; Yang, S; Qi, R et al. J Phys Chem B, DOI://10.1021/acs.jpcb.5b07962 (2015)
Methylated cytosines mutate to transcription factor binding sites that drive tetrapod evolution Ximiao He, Desiree Tillo, Jeff Vierstra, Khund-Sayeed Syed, Callie Deng, Jordan G. Ray, John Stamatoyannopoulos, Peter C. Fitzgerald and Charles Vinson Genome Biol. and Evol. , doi: 10.1093/gbe/evv205 (2015)
Sequence-and Temperature-Dependent Properties of Unfolded and Disordered Proteins from Atomistic Simulations Gül H. Zerze, Robert B Best, and Jeetain Mittal J. Phys. Chem. B, DOI: 10.1021/acs.jpcb.5b08619 (2015)
Proteomic Profiling of Nuclear Fractions from Native Renal Inner Medullary Collecting Duct Cells Christina M. Pickering, Cameron R. Grady, Barbara Medvar, Milad Emamian, Pablo Concha Sandoval, Yue Zhao, Chin-Rang Yang, Hyun Jun Jung, Chung-Lin Chou, Mark A. Knepper Physiol Genomics., DOI: 10.1152/physiolgenomics.00090.2015 (2015)
Structure dependent hydrophobic and hydrophilic interactions between nickel(II) Schiff base complexes and serum albumins: Spectroscopic and docking studies Banabithi Koley Seth, Aurkie Ray, Mousumi Banerjee, Teerna Bhattacharyya, Dhananjay Bhattacharyya, Samita Basu J. Luminescence, doi:10.1016/j.jlumin.2015.11.009 (2015)
Integrated genome-wide analysis of genomic changes and gene regulation in human adrenocortical tissue samples Gara, SK; Wang, Y; Patel, D et al. Nucleic Acids Res., DOI://10.1093/nar/gkv908 (2015)
A Transcriptional Map of the Renal Tubule: Linking Structure to Function Kretzler, M; Ju, W; J. Am. Soc. Nephrol., DOI://10.1681/ASN.2015030242 (2015)
Cell Migration and Invadopodia Formation Require a Membrane-binding Domain of CARMIL2 M. Hunter Lanier, Patrick McConnell and John A. Cooper J. Biol. Chem. , doi: 10.1074/jbc.M115.676882 (2015)
TCF21 hypermethylation in genetically quiescent clear cell sarcoma of the kidney Saskia L. Gooskens, Samantha Gadd, Jaime M. Guidry Auvil, Daniela S. Gerhard, Javed Khan, Rajesh Patidar, Daoud Meerzaman, Qing-Rong Chen, Chih Hao Hsu, Chunhua Yan, Cu Nguyen, Ying Hu, Charles G. Mullighan, Jing Ma, Lawrence J. Jennings, Ronald R. de Krijger, Marry M. van den Heuvel-Eibrink, Malcolm A. Smith, Nicole Ross, Julie M. Gastier-Foster, Elizabeth J. Perlman Oncotarget 6(18):15828-15841 (2015)
An insight into the sialome of the horse fly, Tabanus bromius Ribeiro JM, Kazimirova M, Takac P, Andersen JF, Francischetti IM Insect Biochem. Mol. Biol., DOI://10.1016/j.ibmb.2015.09.002 (2015)
Molecular mechanisms in genetically defined autoinflammatory diseases: disorders of amplified danger signaling de Jesus AA, Canna SW, Liu Y, Goldbach-Mansky R. Annu Rev Immunol., doi: 10.1146/annurev-immunol-032414-112227 (2015)

Functional connectivity classification of autism identifies highly predictive brain features but falls short of biomarker standards Plitt M, Barnes KA, Martin A Neuroimage Clin., doi: 10.1016/j.nicl.2014.12.013. (2015)
Effects of the Mu opioid receptor polymorphism (OPRM1 A118G) on pain regulation, placebo effects and associated personality trait measures Peciña M, Love T, Stohler CS, Goldman D, Zubieta JK Neuropsychopharmacology, doi: 10.1038/npp.2014.272 (2015)
Calculation of Organ Doses for a Large Number of Patients Undergoing CT Examinations Amir Bahadori, Diana Miglioretti, Randell Kruger, Michael Flynn, Sheila Weinmann, Rebecca Smith-Bindman and Choonsik Lee Medical Physics and Informatics, DOI:10.2214/AJR.14.14135 (2015)
Survival of human lymphoma cells requires B-cell receptor engagement by self-antigens Ryan M. Young, Tianyi Wu, Roland Schmitz, Moez Dawood, Wenming Xiao, James D. Phelan, Weihong Xu, Laurence Menard, Eric Meffre, Wing-Chung C. Chan, Elaine S. Jaffe, Randy D. Gascoyne, Elìas Campo, Andreas Rosenwald, German Ott, Jan Delabie, Lisa M. Rimsza, and Louis M. Staudt PNAS, doi: 10.1073/pnas.1514944112 (2015)
Shifts in connectivity during procedural learning after motor cortex stimulation; a combined transcranial magnetic stimulation /functional magnetic resonance imaging study Adam Steel, Sunbin Song, Devin Bageac, Kristine M. Knutson, Ziad S. Saad, Stephen J. Gotts, Eric M. Wassermann, Leonora Wilkinson Cortex, doi:10.1016/j.cortex.2015.10.004 (2015)
Genome Sequences of Multidrug-Resistant Salmonella enterica Serovar Paratyphi B (dT+) and Heidelberg Strains from the Colombian Poultry Chain Pilar Donado-Godoy, Johan F. Bernal, Fernando Rodrìguez, Yolanda Gomez, Richa Agarwala, David Landsman, Leonardo Mariño-Ramìrez Genome Announc., doi: 10.1128/genomeA.01265-15 (2015)

The transcriptional landscape of age in human peripheral blood Peters, MJ; Joehanes, R; Pilling, LC et al. Nat Commun, DOI://10.1038/ncomms9570 (2015)
Empirical Optimization of Interactions between Proteins and Chemical Denaturants in Molecular Simulations Wenwei Zheng, Alessandro Borgia, Madeleine B. Borgia, Benjamin Schuler, and Robert B. Best J. Chem. Theory and Computation, DOI: 10.1021/acs.jctc.5b00778 (2015)
Computational Methods for Structural and Functional Studies of Alzheimer's Amyloid Ion Channels Hyunbum Jang, Fernando Teran Arce, Joon Lee, Alan L. Gillman, Srinivasan Ramachandran, Bruce L. Kagan, Ratnesh Lal, Ruth Nussinov Protein Amyloid Aggregation, doi://10.1007/978-1-4939-2978-8-16 (2015)
Single-cell RNA-Seq resolves cellular complexity in sensory organs from the neonatal inner ear Burns JC, Kelly MC, Hoa M, Morell RJ, Kelley MW Nature Communications, doi: 10.1038/ncomms9557. (2015)
Characterization of the metastatic phenotype of a panel of established osteosarcoma cells Ren, L; Mendoza, A; Zhu, J et al. Oncotarget, DOI://10.18632/oncotarget.5177 (2015)
Interleaved Text/Image Deep Mining on a Large-Scale Radiology Database for Automated Image Interpretation Hoo-Chang Shin, Le Lu, Lauren Kim, Ari Seff, Jianhua Yao, Ronald M. Summers IEEE CVPR , p. 1090-1099 (2015)

Longitudinal clinical trials with adaptive choice of follow-up time Jeffries N, Geller NL Biometrics, doi: 10.1111/biom.12287. E (2015)
Preparation and Crystallization of Riboswitches Alla Peselis, Ang Gao, Alexander Serganov Nucleic Acids Crystallography, doi://10.1007/978-1-4939-2763-0_3 (2015)
Effects of Neural Morphology and Input Distribution on Synaptic Processing by Global and Focal NMDA-Spikes Poleg-Polsky, A PLoS ONE, DOI://10.1371/journal.pone.0140254 (2015)
Dependence of negative-mode electrospray ionization response factors on mobile phase composition and molecular structure for newly-authenticated neutral acylsucrose metabolites Banibrata Ghosh and A. Daniel Jones Analyst, DOI: 10.1039/c4an02124j (2015)
Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumors Peter M. Moyle, Wei Dai, Tzu-Yu Liu, Waleed M. Hussein, Pirashanthini Maruthayanar, James W. Wells, Nigel A.J. McMillan, Mariusz Skwarczynski, Istvan Toth Bioorg. Med. Chem. Lett., doi:10.1016/j.bmcl.2015.10.049 (2015)
Establishment of Par-Polarized Cortical Domains via Phosphoregulated Membrane Motifs Matthew J. Bailey, Kenneth E. Prehoda Developmental Cell, doi://10.1016/j.devcel.2015.09.016 (2015)

MST2-RASSF protein-protein interactions through SARAH domains Goar Sànchez-Sanz, David Matallanas, Lan K. Nguyen, Boris N. Kholodenko, Edina Rosta, Walter Kolch and Nicolae-Viorel Buchete Briefings in Bioinformatics, doi://10.1093/bib/bbv070 (2015)
Uncovering effects of antibiotics on the host and microbiota using transkingdom gene networks Morgun, A; Dzutsev, A; Dong, X et al. Gut, DOI://10.1136/gutjnl-2014-308820 (2015)
Subassemblies and asymmetry in assembly of herpes simplex virus procapsid Aksyuk, AA; Newcomb, WW; Cheng, N et al. MBio, DOI://10.1128/mBio.01525-15 (2015)
GNL3 and SKA3 are novel prostate cancer metastasis susceptibility genes Minnkyong Lee, Kendra A. Williams, Ying Hu, Jonathan Andreas, Shashank J. Patel, Suiyuan Zhang, Nigel P. S. Crawford Clin Exp Metastasis, DOI 10.1007/s10585-015-9745-y (2015)
Putative Prostate Cancer Risk SNP in an Androgen Receptor-Binding Site of the Melanophilin Gene Illustrates Enrichment of Risk SNPs in Androgen Receptor Target Sites Huajie Bu, Narisu Narisu, Bettina Schlick, Johannes Rainer, Thomas Manke, Georg Schäfer, Lorenza Pasqualini, Peter Chines, Michal R. Schweiger, Christian Fuchsberger and Helmut Klocker Human Mutation, DOI: 10.1002/humu.22909 (2015)
Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity Hirahara K, Onodera A, Villarino AV, Bonelli M, Sciumè G, Laurence A3 Sun HW, Brooks SR, Vahedi, Shih HY, Gutierrez-Cruz, Iwata S, Suzuki, Mikami Y, Okamoto Y, Nakayama T, Holland SM, Hunter CA, Kanno Y, O'Shea JJ Immunity, doi: 10.1016/j.immuni.2015.04.014. (2015)

Efficient test for nonlinear dependence of two continuous variables Wang Y, Li Y, Cao H, Xiong M, Shugart YY, Jin L BMC Bioinformatics, doi: 10.1186/s12859-015-0697-7 (2015)
Whole-genome association analysis of treatment response in obsessive-compulsive disorder Qin H, Samuels JF, Wang Y et al. Mol. Psychiatr., doi: 10.1038/mp.2015.32 (2015)
The CENP-A N-tail confers epigenetic stability to centromeres via the CENP-T branch of the CCAN in fission yeast Folco HD, Campbell CS, May KM, Espinoza C, Oegema K, Hardwick KG, Grewal SI, Desai A Curr. Biology, doi: 10.1016/j.cub.2014.11.060 (2015)
RNA sequencing of the nephron transcriptome: A technical note Jae Wook Lee Kidney Research & Clinical Practice, doi:10.1016/j.krcp.2015.08.008 (2015)
Targeted Proteomics-Driven Computational Modeling of Macrophage S1P Chemosensing Manes, NP; Angermann, BR; Koppenol-Raab, M et al. Mol. Cell Proteomics, DOI://10.1074/mcp.M115.048918 (2015)
Genome-wide profiling of nucleosome sensitivity and chromatin accessibility in Drosophila melanogaster Razvan V. Chereji, Tsung-Wai Kan, Magda K. Grudniewska, Alexander V. Romashchenko, Eugene Berezikov, Igor F. Zhimulev, Victor Guryev, Alexandre V. Morozov and Yuri M. Moshkin Nucleic Acids Research, doi: 10.1093/nar/gkv978 (2015)
Identification of Scedosporium boydii catalase A1 gene, a reactive oxygen species detoxification factor highly expressed in response to oxidative stress and phagocytic cells Mina, Staerck et al Fungal Biology, doi:10.1016/j.funbio.2015.09.007 (2015)
Deep Proteomic Profiling of Vasopressin-Sensitive Collecting Duct Cells. II. Bioinformatic Analysis of Vasopressin Signaling Chin-Rang Yang, Viswanathan Raghuram, Milad Emamian, Pablo Concha Sandoval, Mark A. Knepper Am. J. Physiol. - Cell Physiol. , DOI: 10.1152/ajpcell.00214.2015 (2015)
Exposure of chick embryos to cadmium changes the extra-embryonic vascular branching pattern and alters expression of VEGF-A and VEGF-R2 Anna Kaskova Gheorghescu, Bartlomiej Tywoniuk, Johannes Duess, Nicolae-Viorel Buchete, Jennifer Thompson Toxicology & Applied Pharmacology, doi://10.1016/j.taap.2015.09.004 (2015)
Quantitative evaluation of positive φ angle propensity in flexible regions of proteins from three-bond J couplings Jung Ho Lee, Jinfa Ying and Ad Bax Phys. Chem. Chem. Phys., DOI: 10.1039/C5CP04542H (2015)
Turning Cucurbit[8]uril into a Supramolecular Nanoreactor for Asymmetric Catalysis Lifei Zheng, Silvia Sonzini, Masyitha Ambarwati, Edina Rosta, Oren A. Scherman and Andreas Herrmann Angewandte Chemie , DOI: 10.1002/anie.201505628 (2015)
Comparison against 186 canid whole-genome sequences reveals survival strategies of an ancient clonally transmissible canine tumor Brennan Decker, Brian W Davis, Maud Rimbault, Adrienne H Long, Eric Karlins, Heidi G Parker, Vidhya Jagannathan, Rebecca Reiman, Cord Drögemüller, Jason J Corneveaux, Erica S Chapman, Jeffery M Trent, Tosso Leeb, Matthew J Huentelman, Robert K Wayne, Danielle M Karyadi and Elaine A Ostrander Genome Research, doi: 10.1101/gr.190314.115 (2015)

Distinct profiles for mitochondrial t-RNAs and small nucleolar RNAs in locally invasive and metastatic colorectal cancer Lai Xu, Joseph Ziegelbauer, Rong Wang, Wells W Wu, Rong-Fong Shen, Hartmut H Juhl, Yaqin Zhang, and Amy S Rosenberg Clinical Cancer Research, doi: 10.1158/1078-0432.CCR-15-0737 (2015)
Plasma Levels of Soluble IL-2 Receptor α Associations With Clinical Cardiovascular Events and Genome-Wide Association Scan Peter Durda, Jeremy Sabourin, Ethan M. Lange, Mike A. Nalls, Josyf C. Mychaleckyj, Nancy Swords Jenny, Jin Li, Jeremy Walston, Tamara B. Harris, Bruce M. Psaty, William Valdar, Yongmei Liu, Mary Cushman, Alex P. Reiner, Russell P. Tracy, Leslie A. Lange Arteriosclerosis, Thrombosis and Vascular Biology, doi: 10.1161/ATVBAHA.115.305289 (2015)
Single Nucleotide Specific Targeting of the Tf1 Retrotransposon Promoted by the DNA-Binding Protein Sap1 of Schizosaccharomyces pombe Anthony Hickey, Caroline Esnault, Anasuya Majumdar, Atreyi Ghatak Chatterjee, James R. Iben, Philip G. McQueen, Andrew X. Yang, Takeshi Mizuguchi, Shiv I. S. Grewal and Henry L. Levin Genetics, doi: 10.1534/genetics.115.181602 (2015)
Pressure-induced structural transition of mature HIV-1 Protease from a combined NMR/MD simulation approach Julien Roche, John M. Louis, Ad Bax and Robert B. Best Proteins, DOI: 10.1002/prot.24931 (2015)
Histone H3 Lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiation Sugata Manna, Jong Kyong Kim, Catherine Baugé, Margaret Cam, Yongmei Zhao, Jyoti Shetty, Melanie S. Vacchio, Ehydel Castro, Bao Tran, Lino Tessarollo & Rémy Bosselut Nature Communications, doi:10.1038/ncomms9152 (2015)
Tautomerism of Warfarin: Combined Chemoinformatics, Quantum Chemical, and NMR Investigation Laura Guasch, Megan L. Peach, and Marc C Nicklaus J. Org. Chem. , DOI: 10.1021/acs.joc.5b01370 (2015)

Comparative analyses of CTCF and BORIS occupancies uncover two distinct classes of CTCF binding genomic regions Elena M. Pugacheva, Samuel Rivero-Hinojosa, Celso A. Espinoza, et al. Genome Biol. , doi: 10.1186/s13059-015-0736-8 (2015)
Triangulating the sexually dimorphic brain through high-resolution neuroimaging of murine sex chromosome aneuploidies Raznahan, A; Lue, Y; Probst, F et al. Brain Struct Funct, DOI://10.1007/s00429-014-0875-9 (2015)
TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow Yang, Q; Li, F; Harly, C et al. Nat. Immunol., DOI://10.1038/ni.3248 (2015)
Assessing FOXO1A as a potential susceptibility locus for type 2 diabetes and obesity in American Indians Yunhua L. Muller, Robert L. Hanson, Gregory Wiessner, Lori Nieboer, Sayuko Kobes, Paolo Piaggi, Mahdi Abdussamad, Chidinma Okani, William C. Knowler, Clifton Bogardus andLeslie J. Baier Obesity, DOI: 10.1002/oby.21236 (2015)
Correlation of magnetic resonance imaging with digital histopathology in prostate Jin Tae Kwak, Sandeep Sankineni, Sheng Xu, Baris Turkbey, Peter L. Choyke, Peter A. Pinto, Maria Merino, Bradford J. Wood Int. J. CARS, DOI 10.1007/s11548-015-1287-x (2015)
Novel Human-like Influenza A Viruses Circulate in Swine in Mexico and Chile Martha Nelson, Marie R. Culhane, Albert Rovira, Montserrat Torremorell, Pedro Guerrero, and Julio Norambuena PLoS Currents, doi: 10.1371/currents.outbreaks.c8b3207c9bad98474eca3013fa933ca6 (2015)

Three dysconnectivity patterns in treatment-resistant schizophrenia patients and their unaffected siblings Wang J, Cao H, Liao Y et al. Neuroimage Clin. , doi: 10.1016/j.nicl.2015.03.017 (2015)
The jigsaw puzzle of sequence phenotype inference: Piecing together Shannon entropy, importance sampling, and Empirical Bayes Shreif Z, Striegel DA, Periwal V J. Theoretical Biology, doi: 10.1016/j.jtbi.2015.06.010. (2015)
A Deep Insight Into the Sialotranscriptome of the Chagas Disease Vector, Panstrongylus megistus (Hemiptera: Heteroptera) Ribeiro JM, Schwarz A, Francischetti IM J. Med. Entomol., DOI://10.1093/jme/tjv023 (2015)
Defining the Domain Arrangement of the Mammalian Target of Rapamycin Complex Component Rictor Protein Zhou P, Zhang N, Nussinov R, Ma B J. Comput. Biol., DOI://10.1089/cmb.2015.0103 (2015)
Deep Proteomic Profiling of Vasopressin-Sensitive Collecting Duct Cells. I. Virtual Western Blots and Molecular Weight Distributions Chin-Rang Yang, Pumipat Tongyoo, Milad Emamian, Pablo Concha Sandoval, Viswanathan Raghuram, Mark A. Knepper Am. J. Physiol. - Cell Physiol. , DOI: 10.1152/ajpcell.00213.2015 (2015)
Impact of conscious intent on chunking during motor learning Sunbin Song and Leonardo Cohen Learning & Memory, doi: 10.1101/lm.035824.114 (2015)

Small Retinoprotective Peptides Reveal a Receptor-binding Region on Pigment Epithelium-derived Factor Jason Kenealey, Preeti Subramanian, Antonella Comitato, Jeanee Bullock, Laura Keehan, Federica Polato, David Hoover, Valeria Marigo and S. Patricia Becerra J. Biol. Chem. , doi: 10.1074/jbc.M115.645846 (2015)
Amylin-Aβ oligomers at atomic resolution using molecular dynamics simulations: a link between Type 2 diabetes and Alzheimer's disease Michal Baram , Yoav Atsmon-Raz , Buyong Ma , Ruth Nussinov and Yifat Miller Phys. Chem. Chem. Phys., DOI: 10.1039/C5CP03338A (2015)
A Bayesian joint model of menstrual cycle length and fecundity Kirsten J. Lum, Rajeshwari Sundaram, Germaine M. Buck Louis andThomas A. Louis Biometrics, DOI: 10.1111/biom.12379 (2015)
Revealing the fate of cell surface human P-glycoprotein (ABCB1): The lysosomal degradation pathway Katayama, K; Kapoor, K; Ohnuma, S et al. Biochim. Biophys. Acta, DOI://10.1016/j.bbamcr.2015.06.001 (2015)
An Improved F(st) Estimator Chen, G; Yuan, A; Shriner, D et al. PLoS ONE, DOI://10.1371/journal.pone.0135368 (2015)
Genome-wide association study of neocortical Lewy-related pathology Terhi Peuralinna, Liisa Myllykangas, Minna Oinas,, Mike A. Nalls, Hannah A. D. Keage, Veli-Matti Isoviita, Miko Valori, Tuomo Polvikoski, Anders Paetau, Raimo Sulkava, Paul G. Ince, Julia Zaccai, Carol Brayne, Bryan J. Traynor, John Hardy, Andrew B. Singleton and Pentti J. Tienari Annalls of Clinical and Translational Neurology, DOI: 10.1002/acn3.231 (2015)

Confusing placebo effect with natural history in epilepsy: A big data approach Goldenholz DM, Moss R, Scott J, Auh S, Theodore WH Ann. Neurol., DOI://10.1002/ana.24470 (2015)
Possible Human Papillomavirus 38 Contamination of Endometrial Cancer RNA Sequencing Samples in The Cancer Genome Atlas Database Majid Kazemian, Min Ren, Jian-Xin Lin, Wei Liao, Rosanne Spolski and Warren J. Leonard J. Virology, doi: 10.1128/JVI.00822-15 (2015)
The Beta Cell in Its Cluster: Stochastic Graphs of Beta Cell Connectivity in the Islets of Langerhans Deborah A. Striegel, Manami Hara, Vipul Periwal PLoS Computational Biology, DOI: 10.1371/journal.pcbi.1004423 (2015)
Baseline genetic associations in the Parkinson's Progression Markers Initiative (PPMI) Mike A. Nalls, Margaux F. Keller, Dena G. Hernandez, Lan Chen, David J. Stone , Andrew B. Singleton, andon behalf of the Parkinson's Progression Marker Initiative (PPMI) investigators Movement Disorders, DOI: 10.1002/mds.26374 (2015)
Presenilin 1 Maintains Lysosomal Ca2+ Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification Ju-Hyun Lee, Mary Kate McBrayer, Devin M. Wolfe, Luke J. Haslett, Asok Kumar, Yutaka Sato, Pearl P.Y. Lie, Panaiyur Mohan, Erin E. Coffey, Uday Kompella, Claire H. Mitchell, Emyr Lloyd-Evans, Ralph A. Nixon Cell Reports , doi:10.1016/j.celrep.2015.07.050 (2015)
Modeling ligand recognition at the P2Y12 receptor in light of X-ray structural information Paoletta, S; Sabbadin, D; von Kügelgen, I et al. J. Comput. Aided Mol. Des., DOI://10.1007/s10822-015-9858-z (2015)
Gα13 Stimulates the Tyrosine Phosphorylation of Ric-8A Mingda Yan, Ji Ha, Danny Dhanasekaran J. Molecular Signaling, doi://10.5334/1750-2187-10-3 (2015)
Molecular structure of monomorphic peptide fibrils within a kinetically trapped hydrogel network Katelyn Nagy-Smith, Eric Moore, Joel Schneider, and Robert Tycko PNAS, doi: 10.1073/pnas.1509313112 (2015)
Divergence from the classical hydroboration reactivity; boron containing materials through a hydroboration cascade of small cyclic dienes Anna Andreou, Michal Leskes, Pablo G. Jambrina, Gary J. Tustin, Clare P. Grey, Edina Rosta, and Oren A. Scherman Chemical Science, DOI: 10.1039/b000000x (2015)
ABCC8 R1420H loss-of-function variant in a Southwest American Indian community: association with increased birth weight and doubled risk of type 2 diabetes Leslie J. Baier, Yunhua Li Muller, Maria Sara Remedi, Michael Traurig, Paolo Piaggi, Gregory Wiessner, Ke Huang, Alyssa Stacy, Sayuko Kobes, Jonathan Krakoff, Peter H. Bennett, Robert G. Nelson, William C. Knowler, Robert L. Hanson, Colin G. Nichols and Clifton Bogardus Diabetes, doi: 10.2337/db15-0459 (2015)
Comprehensive assembly of novel transcripts from unmapped human RNA-Seq data and their association with cancer Majid Kazemian, Min Ren, Jian‐Xin Lin, Wei Liao, Rosanne Spolski, Warren J Leonard Molecular Systems Biology, DOI 10.15252/msb.156172 (2015)
A β Stretching-and-Packing Cross-Seeding Mechanism Can Trigger Tau Protein Aggregation Ruxi Qi, Yin Luo, Guanghong Wei, Ruth Nussinov, and Buyong Ma J. Phys. Chem Letters, DOI: 10.1021/acs.jpclett.5b01447 (2015)

Membrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory Zoe Cournia, Toby W. Allen et al. J. Membrane Biology, DOI: 10.1007/s00232-015-9802-0 (2015)
Mechanical properties of lipid bilayers from molecular dynamics simulation Richard M. Venable, Frank L.H. Brown, Richard W. Pastor Chemistry and Physics of Lipids, doi:10.1016/j.chemphyslip.2015.07.014 (2015)
Runx1 is required for hematopoietic defects and leukemogenesis in Cbfb-MYH11 knock-in mice Hyde RK, Zhao L, Alemu L, Liu PP Leukemia, DOI://10.1038/leu.2015.58 (2015)
PTH and Vitamin D Repress DMP1 in Cementoblasts Wang L, Tran AB, Nociti FH Jr, Thumbigere-Math V, Foster BL, Krieger CC, Kantovitz KR, Novince CM, Koh AJ, McCauley LK, Somerman MJ J Dent Res. , doi: 10.1177/0022034515599726 (2015)
4'-modified nucleoside analogs: Potent inhibitors active against entecavir-resistant hepatitis B virus Takamatsu Y, Tanaka Y, Kohgo S,, Murakami S, Singh K, Das D, Venzon DJ, Amano M, Higashi-Kuwata N, Aoki M, Delino NS, Hayashi S, Takahashi S, Sukenaga Y, Haraguchi K, Sarafianos SG, Maeda K, Mitsuya H Hepatology, doi: 10.1002/hep.27962 (2015)
Super-enhancers: Asset management in immune cell genomes Steven Witte, John J. O'Shea, Golnaz Vahedi Trends in Immunology, doi: 10.1016/j.it.2015.07.005. (2015)

Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection Hadi M Yassine, Jeffrey C Boyington, Patrick M McTamney, Chih-Jen Wei, Masaru Kanekiyo, Wing-Pui Kong, John R Gallagher, Lingshu Wang, Yi Zhang, M Gordon Joyce, Daniel Lingwood, Syed M Moin, Hanne Andersen, Yoshinobu Okuno, Srinivas S Rao, Audray K Harris, Peter D Kwong, John R Mascola, Gary J Nabel & Barney S Graham Nature Medicine, doi:10.1038/nm.3927 (2015)
Mapsnp: an R package to plot a genomic map for single nucleotide polymorphisms Zhang F, Xu Y, Cao H, Jin C, Cheng Z, Wang G, Shugart YY PLoS One, doi: 10.1371/journal.pone.0123609 (2015)
Distinct transcriptome profiles differentiate nonsteroidal anti-inflammatory drug-dependent from nonsteroidal anti-inflammatory drug-independent food-induced anaphylaxis Muñoz-Cano R, Pascal M, Bartra J, Picado C, Valero A, Kim DK, Brooks S, Ombrello M, Metcalfe DD, Rivera J, Olivera A J Allergy Clin Immunol. , doi: 10.1016/j.jaci.2015.05.042. (2015)
Resting state connectivity of the bed nucleus of the stria terminalis at ultra-high field Salvatore Torrisi, Katherine O'Connell, Andrew Davis, Richard Reynolds, Nicholas Balderston, Julie Fudge, Christian Grillon and Monique Ernst Human Brain Mapping, DOI: 10.1002/hbm.22899 (2015)
Metabolic mapping of A3 adenosine receptor agonist MRS5980 Fang ZZ, Tosh DK, Tanaka N, Wang H, Krausz KW, O'Connor R, Jacobson KA, Gonzalez FJ Biochem Pharmacol., doi: 10.1016/j.bcp.2015.07.007. (2015)
RAG Represents a Widespread Threat to the Lymphocyte Genome Grace Teng, Yaakov Maman, Wolfgang Resch, Min Kim, Arito Yamane, Jason Qian, Kyong-Rim Kieffer-Kwon, Malay Mandal, Yanhong Ji, Eric Meffre, Marcus R. Clark, Lindsay G. Cowell, Rafael Casellas, David G. Schatz Cell, doi:10.1016/j.cell.2015.07.009 (2015)

Variation in the Williams syndrome GTF2I gene and anxiety proneness interactively affect prefrontal cortical response to aversive stimuli Jabbi M, Chen Q, Turner N, Kohn P, White M, Kippenhan JS, Dickinson D, Kolachana B, Mattay V, Weinberger DR, Berman KF Transl Psychiatry., doi: 10.1038/tp.2015.98. (2015)
Improved Expression and Characterization of a Multidomain Xylanase from Thermoanaerobacterium aotearoense SCUT27 in Bacillus subtilis Xiongliang Huang, Zhe Li, Chenyu Du, Jufang Wang, and Shuang Li J. Agric. Food Chem., DOI: 10.1021/acs.jafc.5b01259 (2015)
Areas of Brain Damage Underlying Increased Reports of Behavioral Disinhibition Knutson, KM; Dal Monte, O; Schintu, S et al. J Neuropsychiatry Clin Neurosci, DOI://10.1176/appi.neuropsych.14060126 (2015)
Opposing roles of STAT1 and STAT3 in IL-21 function in CD4+ T cells Wan, CK; Andraski, AB; Spolski, R et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1511711112 (2015)
Gene-Gene Interaction Among WNT Genes for Oral Cleft in Trios Li Q, Kim Y, Suktitipat B, Hetmanski JB, Marazita ML, Duggal P, Beaty TH, Bailey-Wilson JE Genet Epidemiol., doi: 10.1002/gepi.21888. (2015)
Convergent BOLD and Beta-Band Activity in Superior Temporal Sulcus and Frontolimbic Circuitry Underpins Human Emotion Cognition Jabbi M, Kohn PD, Nash T, Ianni A, Coutlee C, Holroyd T, Carver FW, Chen Q, Cropp B, Kippenhan JS, Robinson SE, Coppola R, Berman KF Cerebral Cortex, doi: 10.1093/cercor/bht427. (2015)

An Integrative Genomic Study Implicates the Post-Synaptic Density in the Pathogenesis of Bipolar Disorder Akula N, Wendland JR, Choi KH, McMahon FJ Neuropsychopharmacology, doi: 10.1038/npp.2015.218 (2015)
A mutation of MET, encoding hepatocyte growth factor receptor, is associated with human DFNB97 hearing loss Mujtaba G, Schultz JM, Imtiaz A, Morell RJ, Friedman TB, Naz S J. Med. Genet., DOI://10.1136/jmedgenet-2015-103023 (2015)
Directional dominance on stature and cognition in diverse human populations Joshi, PK; Esko, T; Mattsson, H et al. Nature, DOI://10.1038/nature14618 (2015)
A two-state mixed hidden Markov model for risky teenage driving behavior John C. Jackson, Paul S. Albert, and Zhiwei Zhang Ann. Appl. Stat., doi:10.1214/14-AOAS765 (2015)
Women Workers and Women at Home Are Equally Inactive: NHANES 2003-2006 Steeves JA, Murphy RA, Zipunnikov V, Strath SJ, Harris TB Med Sci Sports Exerc, DOI://10.1249/MSS.0000000000000582 (2015)
Novel genomic signals of recent selection in an Ethiopian population Tekola-Ayele, F; Adeyemo, A; Chen, G et al. Eur. J. Hum. Genet., DOI://10.1038/ejhg.2014.233 (2015)

Genome Analysis of Latin American Cervical Cancer: Frequent Activation of the PIK3CA Pathway Hong Lou, Guillermo Villagran, Joseph F. Boland, Kate M Im, Sarita Polo, Weiyin Zhou, Ushie Odey, Eligia Juàrez-Torres, Ingrid Medina-Martìnez, Edgar Roman-Basaure, Jason Mitchell, David Roberson, Julie Sawitzke, Lisa Garland, Maria Rodrìguez-Herrera, David Wells, Jennifer Troyer, Francisco Castillo, Sara Bass, Xijun Zhang, Miriam Castillo, Bert Gold, Hesler Morales, Meredith Yeager, Jaime Berumen, Enrique Alvirez, Eduardo Gharzouzi, and Michael Dean Clinical Cancer Research, doi:10.1158/1078-0432.CCR-14-1837 (2015)
Bolaamphiphiles as Carriers for siRNA Delivery: From Chemical Syntheses to Practical Applications Kshitij Gupta, Kirill A. Afonin, Mathias Viarda, Virginia Herrero, Wojciech Kasprzak, Ioannis Kagiampakis, Taejin Kim, Alexey Y. Koyfman, Anu Puri, Marissa Stepler, Alison Sappe, Vineet N. KewalRamani, Sarina Grinberg, Charles Linder, Eliahu Heldman, Robert Blumenthal, Bruce A. Shapiro J. Controlled Release, doi:10.1016/j.jconrel.2015.06.041 (2015)
Classification of occupational activity categories using accelerometry: NHANES 2003-2004 Steeves JA, Tudor-Locke C, Murphy RA, King GA, Fitzhugh EC, Harris TB Int J Behav Nutr Phys Act, DOI://10.1186/s12966-015-0235-z (2015)
MitoRCA-seq reveals unbalanced cytocine to thymine transition in Polg mutant mice Ni T, Wei G, Shen T, Han M, Lian Y, Fu H, Luo Y, Yang Y, Liu J, Wakabayashi Y, Li Z, Finkel T, Xu H, Zhu J Scientific Reports, doi: 10.1038/srep12049. (2015)
A Systems Level Analysis of Vasopressin-mediated Signaling Networks in Kidney Distal Convoluted Tubule Cells Lei Cheng, Qi Wu, Marleen L. A. Kortenoeven, Trairak Pisitkun, Robert A. Fenton Sci. Rep. , doi: 10.1038/srep12829 (2015)
Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci Demerath, EW; Guan, W; Grove, ML et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddv161 (2015)

Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations Sonia Shah, Marc J. Bonder, Riccardo E. Marioni et al. Am. J. Hum. Genet. , doi:/10.1016/j.ajhg.2015.05.014 (2015)
2.2 Å resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor Alberto Bartesaghi, Alan Merk, Soojay Banerjee, Doreen Matthies, Xiongwu Wu, Jacqueline L. S. Milne, Sriram Subramaniam Science, DOI: 10.1126/science.aab1576 (2015)
miR-23a impairs bone differentiation in osteosarcoma via down-regulation of GJA1 Gindin Y, Jiang Y, Francis P, Walker RL, Abaan OD, Zhu YJ, Meltzer PS Front Genet. , doi: 10.3389/fgene.2015.00233 (2015)
Motif signatures in stretch enhancers are enriched for disease-associated genetic variants Daniel X Quang, Michael R Erdos, Stephen C J Parker,and Francis S Collins Epigenetics Chromatin, doi: 10.1186/s13072-015-0015-7. (2015)
Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools Ding J, Sidore C, Butler TJ, Wing MK, Qian Y, Meirelles O, Busonero F, Tsoi LC, Maschio A, Angius A, Kang HM, Nagaraja R, Cucca F, Abecasis GR, Schlessinger D PLoS Genetics, doi: 10.1371/journal.pgen.1005306 (2015)
EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion Yang XP, Jiang K, Hirahara K, Vahedi G, Afzali B, Sciume G, Bonelli M, Sun HW, Jankovic D, Kanno Y, Sartorelli V, O'Shea JJ, Laurence A Scientific Reports, doi: 10.1038/srep10643 (2015)

Recurrent Mutations in the Basic Domain of TWIST2 Cause Ablepharon Macrostomia and Barber-Say Syndromes Marchegiani, S; Davis, T; Tessadori, F et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2015.05.017 (2015)
Metabolic Regulation of Histone Acetyltransferases by Endogenous Acyl-CoA Cofactors Montgomery DC, Sorum AW, Guasch L, Nicklaus MC, Meier JL Chem Biol., doi: 10.1016/j.chembiol.2015.06.015. (2015)
RNA-Seq analysis of high NaCl-induced gene expression Izumi Y, Yang W, Zhu J, Burg MB, Ferraris JD Physiol Genomics., doi: 10.1152/physiolgenomics.00057.2015 (2015)
Transcriptome dynamics of developing photoreceptors in three-dimensional retina cultures recapitulates temporal sequence of human cone and rod differentiation revealing cell surface markers and gene networks Kaewkhaw R, Kaya KD, Brooks M, Homma K, Zou J, Chaitankar V, Rao M, Swaroop A Stem Cells, doi: 10.1002/stem.2122. (2015)
Positing, fitting, and selecting regression models for pooled biomarker data Mitchell EM, Lyles RH, Schisterman EF Stat Med, DOI://10.1002/sim.6496 (2015)
Dietary fatty acids modulate associations between genetic variants and circulating fatty acids in plasma and erythrocyte membranes: Meta-analysis of nine studies in the CHARGE consortium Smith, CE; Follis, JL; Nettleton, JA et al. Mol Nutr Food Res, DOI://10.1002/mnfr.201400734 (2015)

An Insight into the Sialome of the Lone Star Tick, Amblyomma americanum, with a Glimpse on Its Time Dependent Gene Expression Karim S, Ribeiro JM PLoS ONE, DOI://10.1371/journal.pone.0131292 (2015)
Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder , ; de Moor, MH; van den Berg, SM et al. JAMA Psychiatry, DOI://10.1001/jamapsychiatry.2015.0554 (2015)
GTP-Dependent K-Ras Dimerization Muratcioglu S, Chavan TS, Freed BC, Jang H, Khavrutskii L, Freed RN, Dyba MA, Stefanisko K, Tarasov SG, Gursoy A, Keskin O, Tarasova NI, Gaponenko V, Nussinov R Structure, doi: 10.1016/j.str.2015.04.019 (2015)
New monogenic autoinflammatory diseases--a clinical overview Canna SW, Goldbach-Mansky R Semin Immunopathol. , oi: 10.1007/s00281-015-0493-5 (2015)
Tracking ongoing cognition in individuals using brief, whole-brain functional connectivity patterns Javier Gonzalez-Castillo, Colin W. Hoy, Daniel A. Handwerker, Meghan E. Robinson, Laura C. Buchanan, Ziad S. Saad, and Peter A. Bandettini PNAS, doi: 10.1073/pnas.1501242112 (2015)
Forgetting the best when predicting the worst: Preliminary observations on neural circuit function in adolescent social anxiety Jarcho JM, Romer AL, Shechner T, Galvan A, Guyer AE, Leibenluft E, Pine DS, Nelson EE Dev Cogn Neurosci. , doi: 10.1016/j.dcn.2015.03.002 (2015)

Influenza A Viruses of Human Origin in Swine, Brazil Martha I. Nelson , Rejane Schaefer, Danielle Gava, Maurìcio Egĩdio Cantão, and Janice Reis Ciacci-Zanella Emerg Infect Dis. , doi://10.3201/eid2108.141891 (2015)
Acute and recent air pollution exposure and cardiovascular events at labour and delivery Tuija Männistö, Pauline Mendola, Katherine Laughon Grantz, Kira Leishear, Rajeshwari Sundaram, Seth Sherman, Qi Ying, Danping Liu Heart, doi:10.1136/heartjnl-2014-307366 (2015)
Proteomic analysis of the kidney filtration barrier�Problems and perspectives Markus M. Rinschen Thomas Benzing, Kavee Limbutara and Trairak Pisitkun Proteomics Clinical Applications, DOI: 10.1002/prca.201400201 (2015)
Homologous Mutation to Human BRAF V600E Is Common in Naturally Occurring Canine Bladder Cancer--Evidence for a Relevant Model System and Urine-Based Diagnostic Test Decker B, Parker HG, Dhawan D, Kwon EM, Karlins E, Davis BW, Ramos-Vara JA, Bonney PL, McNiel EA, Knapp DW, Ostrander EA Mol Cancer Res, doi: 10.1158/1541-7786.MCR-14-0689 (2015)
Nucleosome adaptability conferred by sequence and structural variations in histone H2A-H2B dimers Shaytan AK, Landsman D, Panchenko AR Curr Opin Struct Biol., doi: 10.1016/j.sbi.2015.02.004 (2015)
Possible HPV38 contamination of endometrial cancer RNA-Seq samples in The Cancer Genome Atlas database Majid Kazemian, Min Ren, Jian-Xin Lin, Wei Liao, Rosanne Spolski and Warren J. Leonard J. Virology, doi: 10.1128/JVI.00822-15 (2015)

Assessment of Cancer Cell Line Representativeness Using Microarrays for Merkel Cell Carcinoma Kenneth Daily, Amy Coxon, Jonathan S Williams, Chyi-Chia R Lee, Daniel G Coit, Klaus J Busam and Isaac Brownell J. Investigative Dermatology, doi:10.1038/jid.2014.518 (2015)
Shared genetic basis for migraine and ischemic stroke Rainer Malik, Tobias Freilinger et al. Neurology, doi: 10.1212/WNL.0000000000001606 (2015)
Quantitative Interpretation of FRET Experiments via Molecular Simulation: Force Field and Validation Robert B. Best, Hagen Hofmann, Daniel Nettell, Benjamin Schuler Biochemistry, doi:10.1016/j.bpj.2015.04.038 (2015)
Coupling of Zinc-Binding and Secondary Structure in Nonfibrillar Aβ40 Peptide Oligomerization Xu L, Shan S, Chen Y, Wang X, Nussinov R, Ma B J Chem Inf Model, DOI://10.1021/acs.jcim.5b00063 (2015)
DNA methylome and transcriptome sequencing in human ovarian granulosa cells links age-related changes in gene expression to gene body methylation and 3'-end GC density Yu B, Russanova VR, Gravina S, Hartley S, Mullikin JC, Ignezweski A6 Graham J, Segars JH, DeCherney AH, Howard BH Oncotarget, 6(6): 3627-3643. (2015)
Gene Level Meta-Analysis of Quantitative Traits by Functional Linear Models Ruzong Fan, Yifan Wang, Michael Boehnke, Wei Chen, Yun Li, Haobo Ren, Iryna Lobach and Momiao Xiong Genetics, doi: 10.1534/genetics.115.178343 (2015)

Homology modeling of larger proteins guided by chemical shifts Yang Shen & Ad Bax Nature Methods, doi:10.1038/nmeth.3437 (2015)
Conformational processing of oncogenic v-Src kinase by the molecular chaperone Hsp90 Edgar E. Boczek , Lasse G. Reefschläger, Marco Dehling, Tobias J. Struller , Elisabeth Häusler , Andreas Seidl , Ville R. I. Kaila , and Johannes Buchner PNAS, oi: 10.1073/pnas.1424342112 (2015)
Etiologic Ischemic Stroke Phenotypes in the NINDS Stroke Genetics Network Hakan Ay, Ethem Murat Arsava, Gunnar Andsberg et al. Stroke, doi: 10.1161/STROKEAHA.114.007362 (2015)
Insertion Sequence IS26 Reorganizes Plasmids in Clinically Isolated Multidrug-Resistant Bacteria by Replicative Transposition He, S; Hickman, AB; Varani, AM et al. MBio, DOI://10.1128/mBio.00762-15 (2015)
Identification of microRNAs specific for epithelial cell adhesion molecule�positive tumor cells in hepatocellular carcinoma Junfang Ji, Xin Zheng, Marshonna Forgues, Taro Yamashita, Eliane L. Wauthier, Lola M. Reid, Xinyu Wen, Young Song, Jun S. Wei, Javed Khan, Snorri S. Thorgeirsson andXin Wei Wang Hepatology, doi: 10.1002/hep.27886. (2015)
High-level expression of human arginase I in Pichia pastoris and its immobilization on chitosan to produce L-ornithine Xue Zhang, Jin Liu, Xianhong Yu, Fei Wang, Li Yi, Zhezhe Li, Yunyun Liu, and Lixin Macorresponding author BMC Biotechnol. , doi: 10.1186/s12896-015-0184-2 (2015)
Expression and Characterization of the RKOD DNA Polymerase in Pichia pastoris Fei Wang, Shuntang Li, Hui Zhao, Lu Bian, Liang Chen, Zhen Zhang, Xing Zhong, Lixin Ma, Xiaolan Yu PLoS One, doi: 10.1371/journal.pone.0131757 (2015)
Model-free functional connectivity and impulsivity correlates of alcohol dependence: a resting-state study Zhu X, Cortes CR, Mathur K, Tomasi D, Momenan R Addict Biol. , doi: 10.1111/adb.12272 (2015)
Pretreatment Differences in BOLD Response to Emotional Faces Correlate with Antidepressant Response to Scopolamine Furey ML, Drevets WC, Szczepanik J, Khanna A, Nugent A, Zarate CA Int. J. Neuropsychopharmacol., DOI://10.1093/ijnp/pyv028 (2015)
Sliding Motility, Biofilm Formation, and Glycopeptidolipid Production in Mycobacterium colombiense Strains Maya-Hoyos M, Leguizam�n J, Mari�o-Ram�rez L, Soto CY Biomed Res Int. , doi: 10.1155/2015/419549 (2015)
Gene expression markers of age-related inflammation in two human cohorts Pilling LC, Joehanes R, Melzer D, Harries LW, Henley W, Dupuis J, Lin H, Mitchell M, Hernandez D, Ying SX, Lunetta KL, Benjamin EJ, Singleton A, Levy D, Munson P, Murabito JM, Ferrucci L Exp Gerontol. , doi: 10.1016/j.exger.2015.05.012 (2015)
The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence P Suchankova, J Yan, M L Schwandt, B L Stangl, E C Caparelli, R Momenan, E Jerlhag, J A Engel, C A Hodgkinson, M Egli, M F Lopez, H C Becker, D Goldman, M Heilig, V A Ramchandani, and L Leggio Transl Psychiatry. , doi: 10.1038/tp.2015.68 (2015)

Topological polymorphism of the two-start chromatin fiber Norouzi D, Zhurkin VB Biophys. J., doi: 10.1016/j.bpj.2015.04.015 (2015)
A genome-wide association study of suicidal behavior Galfalvy H, Haghighi F, Hodgkinson C, Goldman D, Oquendo MA, Burke A, Huang YY, Giegling I, Rujescu D, Bureau A, Turecki G, Mann JJ Am J Med Genet B Neuropsychiatr Genet. , doi: 10.1002/ajmg.b.32330 (2015)
Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors Zhou T, Lynch RM, Chen L et al. Cell, doi: 10.1016/j.cell.2015.05.007 (2015)
Group Differences in MEG-ICA Derived Resting State Networks: Application to Major Depressive Disorder Allison C. Nugent, Stephen E. Robinson, Richard Coppola, Maura L. Furey, Carlos A. Zarate Jr NeuroImage, doi:10.1016/j.neuroimage.2015.05.051 (2015)
APOL1 G1 genotype modifies the association between HDLC and kidney function in African Americans Bentley, AR; Divers, J; Shriner, D et al. BMC Genomics, DOI://10.1186/s12864-015-1645-7 (2015)
A liver-enriched long non-coding RNA, lncLSTR, regulates systemic lipid metabolism in mice Li P, Ruan X, Yang L, Kiesewetter K, Zhao Y, Luo H, Chen Y, Gucek M, Zhu J, Cao H Cell Metabolism, doi: 10.1016/j.cmet.2015.02.004 (2015)

24, 25-Dihydroxyvitamin D 3 and Vitamin D Status of Community-Dwelling Black and White Americans Anders H. Berg, Camille E. Powe, Michele K. Evans, Julia Wenger, Guillermo Ortiz, Alan B. Zonderman, Pirianthini Suntharalingam, Kathryn Lucchesi, Neil R. Powe, S. Ananth Karumanchi, and Ravi I. Thadhani Clinical Chemistry, doi:10.1373/clinchem.2015.240051 (2015)
A cis-eQTL in PFKFB2 is associated with diabetic nephropathy, adiposity and insulin secretion in American Indians Muller YL, Piaggi P, Hanson RL, Kobes S, Bhutta S, Abdussamad M, Leak-Johnson T, Kretzler M, Huang , Weil EJ, Nelson RG, Knowler WC, Bogardus C, Baier LJ Hum Mol Genet. , doi: 10.1093/hmg/ddv040 (2015)
Converging evidence implicates the abnormal microRNA system in schizophrenia. Zhang F, Xu Y, Shugart YY, Yue W, Qi G, Yuan G, Cheng Z, Yao J, Wang J, Wang G, Cao H, Guo W, Zhou Z, Wang Z, Tian L, Jin C, Yuan J, Liu C, Zhang D Schizophrenia Bulletin, doi: 10.1093/schbul/sbu (2015)
Endoplasmic reticulum-associated amino-peptidase 1 and rheumatic disease: genetics Ombrello MJ, Kastner DL, Remmers EF Curr Opin Rheumatol, DOI://10.1097/BOR.0000000000000189 (2015)
Confirmation of genetic variants associated with lethal prostate cancer in a cohort of men from hereditary prostate cancer families Karyadi DM, Zhao S, He Q, McIntosh L, Wright JL, Ostrander EA, Feng Z, Stanford JL. Int. J. Cancer, doi: 10.1002/ijc.29241 (2015)
Baseline working memory activation deficits in dimensional anxious depression as detected by magnetoencephalography Ionescu, DF; Nugent, AC; Luckenbaugh, DA et al. Acta Neuropsychiatr, DOI://10.1017/neu.2014.46 (2015)
Mutation-targeted therapy with sunitinib or everolimus in patients with advanced low-grade or intermediate-grade neuroendocrine tumours of the gastrointestinal tract and pancreas with or without cytoreductive surgery: protocol for a phase II clinical trial Neychev, V; Steinberg, SM; Cottle-Delisle, C et al. BMJ Open, DOI://10.1136/bmjopen-2015-008248 (2015)
Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project Paul L. Auer, Mike Nalls, James F. Meschia, et al. JAMA Neurology, doi:10.1001/jamaneurol.2015.0582 (2015)
Aβ(1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease Yiling Xiao, Buyong Ma, Dan McElheny, Sudhakar Parthasarathy, Fei Long, Minako Hoshi, Ruth Nussinov & Yoshitaka Ishii Nat Struct Mol Biol, doi:10.1038/nsmb.2991 (2015)
Infrared, Raman, and Ultraviolet Absorption Spectra and Theoretical Calculations and Structure of 2,3,5,6-Tetrafluoropyridine in its Ground and Excited Electronic States Hong-Li Sheu, Praveenkumar Boopalachandran, Sunghwan Kim, Jaan Laane Chemical Physics, doi:10.1016/j.chemphys.2015.04.011 (2015)
PAPST, a User Friendly and Powerful Java Platform for ChIP-Seq Peak Co-Localization Analysis and Beyond Paul W. Bible , Yuka Kanno, Lai Wei, Stephen R. Brooks, John J. O'Shea, Maria I. Morasso, Rasiah Loganantharaj, Hong-Wei Sun PLoS One, DOI: 10.1371/journal.pone.0127285 (2015)
Deep Sequencing Analysis of the Ixodes ricinus Haemocytome Kotsyfakis M, Kopáček P, Franta Z, Pedra JH, Ribeiro JM PLoS Negl Trop Dis, DOI://10.1371/journal.pntd.0003754 (2015)

Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus Tinoush Moulaei, Kabamba B Alexandre, Shilpa R Shenoy, Joel R Meyerson, Lauren RH Krumpe, Brian Constantine, Jennifer Wilson, Robert W Buckheit, Jr., James B McMahon, Sriram Subramaniam, Alexander Wlodawer, Barry R O'Keefe Retrovirology, doi: 10.1186/s12977-014-0127-3 (2015)
High-level expression and characterization of a thermophilic β-mannanase from Aspergillus niger in Pichia pastoris Shi Yu, Zhezhe Li, Yaping Wang, Wanping Chen, Lin Fu, Wei Tang, Chen Chen, Yunyun Liu, Xue Zhang, Lixin Ma Biotechnology Letters, doi://10.1007/s10529-015-1848-7 (2015)
Vasopressin-regulated miRNAs and AQP2-targeting miRNAs in kidney collecting duct cells Jae-Eun Kim, Hyun Jun Jung, Yu-Jung Lee, Tae-Hwan Kwon Am. J. Physiol. - Renal Physiol., DOI: 10.1152/ajprenal.00334.2014 (2015)
Cooperativity and evolution of Tetrahymena two-domain arginine kinase Noriko Okazaki, Shou Motomura, Nanaka Okazoe, Daichi Yano, Tomohiko Suzuki Int. J. Biological Macromolecules, doi:10.1016/j.ijbiomac.2015.05.034 (2015)
New findings support the association of DISC1 genetic variants with susceptibility to schizophrenia in the Han Chinese population Luo X, Jin C, Zhou Z, Shugart YY, Liu X, Zhang F, Zhang F, Zhu J, Wang Y, Cheng Z Psychiatry Res., doi: 10.1016/j.psychres.2015.05.115 (2015)
Combined influence of linker DNA and histone tails on nucleosome dynamics as revealed by microsecond molecular dynamics simulations Alexey K. Shaytana, Grigoriy A. Armeev, Alexander Goncearenco, Victor B. Zhurkin, David Landsman & Anna R. Panchenkoa J Biomol Struct Dyn., doi: 10.1080/07391102.2015.1032630. (2015)

Transcriptional activation by the thyroid hormone receptor through ligand-dependent receptor recruitment and chromatin remodelling Lars Grøntved, Joshua J. Waterfall, Dong Wook Kim, Songjoon Baek, Myong-Hee Sung, Li Zhao, Jeong Won Park, Ronni Nielsen, Robert L. Walker, Yuelin J. Zhu, Paul S. Meltzer, Gordon L. Hager & Sheue-yann Cheng Nature Communications, doi:10.1038/ncomms8048 (2015)
Elucidation of RNA binding regions of gonadotropin-regulated testicular RNA helicase (GRTH/DDX25) to transcripts of a chromatin remodeling protein essential for spermatogenesis Ruifeng Yang, Chon-Hwa Tsai-Morris, Jung Hoon Kang, Maria L. Dufau Hormone Molecular Biology and Clinical Investigation, DOI: 10.1515/hmbci-2015-0004 (2015)
A combined coarse-grained and all-atom simulation of TRPV1 channel gating and heat activation Wenjun Zheng and Feng Qin J. Gen. Physiol. , doi: 10.1085/jgp.201411335 (2015)
Mixed model and estimating equation approaches for zero inflation in clustered binary response data with application to a dating violence study Kara A. Fulton, Danping Liu, Denise L. Haynie, and Paul S. Albert The Annals of Applied Statistics, doi:10.1214/14-AOAS791 (2015)
Cortisol Stress Response in Men and Women Modulated Differentially by the Mu-Opioid Receptor Gene Polymorphism OPRM1 A118G Lovallo WR, Enoch MA, Acheson A, Cohoon AJ, Sorocco KH, Hodgkinson CA, Vincent AS, Glahn DC, Goldman D Neuropsychopharmacology., doi: 10.1038/npp.2015.101 (2015)
The DNA repair endonuclease Mus81 facilitates fast DNA replication in the absence of exogenous damage Fu H, Martin MM, Regairaz M, Huang L, You Y, Lin CM, Ryan M, Kim R, Shimura T, Pommier Y, Aladjem M Nature Communications, doi: 10.1038/ncomms7746. (2015)

miR-26a and miR-384-5p are required for LTP maintenance and spine enlargement Gu QH, Yu D, Hu Z, Liu X, Yang Y, Luo Y, Zhu J, Li Z Nature Communications, doi: 10.1038/ncomms7789 (2015)
High incidence of unrecognized visceral/neurological late-onset Niemann-Pick disease, type C1, predicted by analysis of massively parallel sequencing data sets Wassif CA, Cross JL, Iben J, Sanchez-Pulido L, Cougnoux A, Platt FM, Ory DS, Ponting CP, Bailey-Wilson JE, Biesecker LG, Porter FD Genet Med. , doi: 10.1038/gim.2015.25. (2015)
Molecular profiling and targeted therapy for advanced thoracic malignancies: a biomarker-derived, multiarm, multihistology phase II basket trial Lopez-Chavez A, Thomas A, Rajan A, Raffeld M, Morrow B, Kelly R, Carter CA, Guha U, Killian K, Lau CC, Abdullaev Z, Xi L, Pack S, Meltzer PS, Corless CL, Sandler A, Beadling C, Warrick A, Liewehr DJ, Steinberg SM, Berman A, Doyle A, Szabo E, Wang Y, Giaccone G J Clin Oncol. , doi: 10.1200/JCO.2014.58.2007 (2015)
p53 loss increases the osteogenic differentiation of bone marrow stromal cells He Y, de Castro LF, Shin MH, Dubois W, Yang HH, Jiang S, Mishra PJ, Ren L, Gou H, Lal A, Khanna C, Merlino G, Lee M, Robey PG, Huang J. Stem Cells, doi: 10.1002/stem.1925. (2015)
Commensal-dendritic-cell interaction specifies a unique protective skin immune signature Naik S, Bouladoux N, Linehan JL, Han SJ, Harrison OJ, Wilhelm C, Conlan S, Himmelfarb S, Byrd AL, Deming C, Quinones M, Brenchley JM, Kong HH, Tussiwand R, Murphy KM, Merad M, Segre JA, Belkaid Y Nature, doi: 10.1038/nature14052 (2015)
Automated prostate cancer detection using T2-weighted and high-b-value diffusion-weighted magnetic resonance imaging Jin Tae Kwak, Sheng Xu, Bradford J. Wood, Baris Turkbey, Peter L. Choyke, Peter A. Pinto, Shijun Wang and Ronald M. Summers Medical Physics, doi://10.1118/1.4918318 (2015)

SNPfisher: tools for probing genetic variation in laboratory-reared zebrafish Matthew G. Butler, James R. Iben, Kurt C. Marsden, Jonathan A. Epstein, Michael Granato and Brant M. Weinstein Development, doi: 10.1242/dev.118786 (2015)
X Chromosome and Autosome Dosage Responses in Drosophila melanogaster Heads Zhen-Xia Chen and Brian Oliver Genes | Genomes | Genetics, doi://10.1534/g3.115.017632 (2015)
Dissecting the Roles of MicroRNAs in Coronary Heart Disease via Integrative Genomic Analyses Tianxiao Huan, Jian Rong, Kahraman Tanriverdi, Qingying Meng, Anindya Bhattacharya, David D. McManus, Roby Joehanes, Themistocles L. Assimes, Ruth McPherson, Nilesh J. Samani, Jeanette Erdmann, Heribert Schunkert, Coronary ARteryDIsease Genome wide Replication and Meta-analysis (CARDIoGRAM) Consortium, Paul Courchesne, Peter J. Munson, Andrew D. Johnson, Christopher J. O'Donnell, Bin Zhang, Martin G. Larson, Jane E. Freedman, Daniel Levy, Xia Yang Arteriosclerosis, Thrombosis, and Vascular Biology, doi: 10.1161/ATVBAHA.114.305176 (2015)
Mutations decouple proton transfer from phosphate cleavage in the dUTPase catalytic reaction Anna Lopata, Pablo G. Jambrina, Pankaz K. Sharma, Bernard R. Brooks, Judit Toth, Beata G. Vertessy, and Edina Rosta ACS Catalysis, DOI: 10.1021/cs502087f (2015)
Pleiotropy Analysis of Quantitative Traits at Gene Level by Multivariate Functional Linear Models Wang Y, Liu A, Mills JL, Boehnke M, Wilson AF, Bailey-Wilson JE, Xiong M, Wu CO, Fan R Genet Epidemiol., doi: 10.1002/gepi.21895 (2015)
Modeling the effect of codon translation rates on co-translational protein folding mechanisms of arbitrary complexity Luca Caniparoli and Edward P. O'Brien J. Chem. Phys., doi://10.1063/1.4916914 (2015)

A Functional Data Analysis Approach for Circadian Patterns of Activity of Teenage Girls Ruzong Fan, Victoria Chen, Yunlong Xie, Lanlan Yin, Sungduk Kim, Paul S Albert, Bruce Simons-Morton J. Circadian Rhythms, DOI: 10.5334/jcr.ac (2015)
Continual Reintroduction of Human Pandemic H1N1 Influenza A Viruses into Swine in the United States, 2009 to 2014 Martha I. Nelson, Jered Stratton, Mary Lea Killian, Alicia Janas-Martindale and Amy L. Vincent J. Virology, doi: 10.1128/JVI.00459-15 (2015)
Global migration of influenza A viruses in swine Martha I. Nelson, Cècile Viboud, Amy L. Vincent, Marie R. Culhane, Susan E. Detmer, David E. Wentworth, Andrew Rambaut, Marc A. Suchard, Edward C. Holmes & Philippe Lemey Nature Communications, doi:10.1038/ncomms7696 (2015)
Towards predicting metastatic progression of melanoma based on gene expression data Yuanyuan Li, Juno M. Krahn, Gordon P. Flake, David M. Umbach andLeping Li Pigment Cell and Melanoma Research, DOI: 10.1111/pcmr.12374 (2015)
An Integrated Bayesian Nonparametric Approach for Stochastic and Variability Orders in ROC Curve Estimation: An Application to Endometriosis Diagnosis Beom Seuk Hwang & Zhen Chena* J. Am. Stat. Assoc., DOI:10.1080/01621459.2015.1023806 (2015)
Identification of Mutational Hot Spots for Substrate Diffusion: Application to Myoglobin David De Sancho, Adam Kubas, Po-Hung Wang, Jochen Blumberger, and Robert B. Best J. Chem. Theory Comput. , DOI: 10.1021/ct5011455 (2015)

Genome-wide identification of microRNA expression quantitative trait loci Tianxiao Huan, Jian Rong, Chunyu Liu, Xiaoling Zhang, Kahraman Tanriverdi, Roby Joehanes, Brian H. Chen, Joanne M. Murabito, Chen Yao, Paul Courchesne, Peter J. Munson, Christopher J. O'Donnell, Nancy Cox, Andrew D. Johnson, Martin G. Larson, Daniel Levy & Jane E. Freedman Nature Communications, doi:10.1038/ncomms7601 (2015)
Molecular modeling of the human P2Y14 receptor: A template for structure-based design of selective agonist ligands Kevin Trujillo, Silvia Paoletta, Evgeny Kiselev, Kenneth A. Jacobson Bioorganic & Medicinal Chemistry, doi:10.1016/j.bmc.2015.03.042 (2015)
Detection and characterization of nonspecific, sparsely populated binding modes in the early stages of complexation Antonio Cardone, Aaron Bornstein, Harish C. Pant, Mary Brady, Ram Sriram and Sergio A. Hassan J. Computational Chemistry, DOI: 10.1002/jcc.23883 (2015)
An Apela RNA-Containing Negative Feedback Loop Regulates p53-Mediated Apoptosis in Embryonic Stem Cells Li M, Gou H, Tripathi BK, Huang J, Jiang S, Dubois W, Waybright T, Lei M, Shi J, Zhou M, Huang J Cell Stem Cell , doi: 10.1016/j.stem.2015.04.002 (2015)
Single-unit activity during natural vision: diversity, consistency, and spatial sensitivity among AF face patch neurons McMahon DB, Russ BE, Elnaiem HD, Kurnikova AI, Leopold DA J. Neurosci., DOI://10.1523/JNEUROSCI.3825-14.2015 (2015)
Expression, Activation and Characterization of Porcine Trypsin in Pichia pastoris GS115 Min Shu, Wei Shen, Xiaojuan Wang, Fei Wang, Lixin Ma, , Chao Zhai Protein Expression and Purification, Protein Expression and Purification (2015)
The Structure of an Oxalate Oxidoreductase Provides Insight into Microbial 2-Oxoacid Metabolism Marcus I. Gibson, Edward J. Brignole, Elizabeth Pierce, Mehmet Can Stephen W. Ragsdale, and Catherine L. Drennan Biochemistry, DOI: 10.1021/acs.biochem.5b00521 (2015)
Mutation rate and genotype variation of Ebola virus from Mali case sequences T. Hoenen, D. Safronetz, A. Groseth, K. R. Wollenberg, O. A. Koita, B. Diarra, I. S. Fall, F. C. Haidara, F. Diallo, M. Sanogo, Y. S. Sarro, A. Kone, A. C. G. Togo, A. Traore, M. Kodio, A. Dosseh, K. Rosenke, E. de Wit, F. Feldmann, H. Ebihara, V. J. Munster, K. C. Zoon, H. Feldmann, S. Sow Science, DOI: 10.1126/science.aaa5646 (2015)
Deep Sequencing in Microdissected Renal Tubules Identifies Nephron Segment-Specific Transcriptomes Jae Wook Lee, Chung-Lin Chou and Mark A. Knepper J. Am. Soc. Nephrology, doi: 10.1681/ASN.2014111067 (2015)
S Values for 131I based on the ICRP Adult Voxel Phantoms Stephanie Lamart, Steven L. Simon, Andre Bouville, Brian E. Moroz and Choonsik Lee Radiation Protection Dosimetry, doi: 10.1093/rpd/ncv016 (2015)
Engineering of customized meganucleases via in vitro compartmentalization and in cellulo optimization Ryo Takeuchi, Michael Choi, Barry L. Stoddard Methods Mol Biol., doi: 10.1007/978-1-4939-1862-1_6 (2015)
The relationship between glucose metabolism, resting-state fMRI BOLD signal, and GABAA-binding potential: a preliminary study in healthy subjects and those with temporal lobe epilepsy Nugent AC, Martinez A, D'Alfonso A, Zarate CA, Theodore WH J. Cereb. Blood Flow Metab., DOI://10.1038/jcbfm.2014.228 (2015)

Is visual registration equivalent to semiautomated registration in prostate biopsy Kwak, JT; Hong, CW; Pinto, PA et al. Biomed Res Int, DOI://10.1155/2015/394742 (2015)
Rare variants in neuronal excitability genes influence risk for bipolar disorder Ament SA, Szelinger S, Glusman G, Ashworth J, Hou L, Akula N, Shekhtman T, Badner JA, Brunkow ME, Mauldin DE, Stittrich AB, Rouleau K, Detera-Wadleigh SD, Nurnberger JI Jr, Edenberg HJ, Gershon ES, Schork N; Bipolar Genome Study, Price ND, Gelinas R, Hood L, Craig D, McMahon FJ, Kelsoe JR, Roach JC PNAS, doi: 10.1073/pnas.1424958112 (2015)
Computational and experimental studies of reassociating RNA/DNA hybrids containing split functionalities Afonin KA, Bindewald E, Kireeva M, Shapiro BA Methods Enzymol. , doi: 10.1016/bs.mie.2014.10.058 (2015)
Common genetic variants influence human subcortical brain structures Hibar DP, Stein JL, Renteria ME et al. Nature, doi: 10.1038/nature14101 (2015)
Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium Li Q, Wojciechowski R, Simpson CL et al. Human Genetics, doi: 10.1007/s00439-014-1500-y. (2015)
The bigger they are, the harder they fall: A topical review on sedimented solutes for solid-state NMR Enrico Ravera Concepts in Magnetic Resonance, DOI: 10.1002/cmr.a.21318 (2015)
Renal Type A Intercalated Cells Contain Albumin in Organelles with Aldosterone-Regulated Abundance Thomas Buus Jensen, Muhammad Umar Cheema, Agata Szymiczek, Helle Hasager Damkier, and Jeppe Praetorius PLoS One, doi: 10.1371/journal.pone.0124902 (2015)
A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension Tianxiao Huan , Tõnu Esko , Marjolein J. Peters et al. PLoS Genetics, DOI: 10.1371/journal.pgen.1005035 (2015)
Nucleus detection using gradient orientation information and linear least squares regression Jin Tae Kwak ; Stephen M. Hewitt ; Sheng Xu ; Peter A. Pinto ; Bradford J. Wood Proc. SPIE Medical Imaging 2015, doi:10.1117/12.2081413 (2015)
Characterization of the p300 Taz2-p53 TAD2 complex and comparison with the p300 Taz2-p53 TAD1 complex Miller Jenkins, LM; Feng, H; Durell, SR et al. Biochemistry, DOI://10.1021/acs.biochem.5b00044 (2015)
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility Jennifer Wessel, Audrey Y Chu, Sara M Willems et al. Nature Communications, doi: 10.1038/ncomms6897 (2015)
A Rapid and Simple Screening Method to Identify Conditions for Enhanced Stability of Modular Vaccine Candidates Alemu Tekewe, Natalie K. Connorsa , Frank Sainsbury, Nani Wibowo, Linda H.L. Lua, Anton P.J. Middelberg Biochemical Engg. Journal, doi:10.1016/j.bej.2015.04.004 (2015)
Computational Structural Analysis of C-Terminal Residues of Proteins Containing Transmembrane Regions M.C. Rishyakulya, K.M. Saravanan Int. J. Comp. Biol. 4(1):44-54 (2015)
Clonality and Evolutionary History of Rhabdomyosarcoma Li Chen , Jack F. Shern , Jun S. Wei, Marielle E. Yohe, Young K. Song, Laura Hurd, Hongling Liao, Daniel Catchpoole, Stephen X. Skapek, Frederic G. Barr, Douglas S. Hawkins, Javed Khan PLos Genetics, DOI: 10.1371/journal.pgen.1005075 (2015)
Practice Structure Improves Unconscious Transitional Memories by Increasing Synchrony in a Premotor Network. Song S, Gotts SJ, Dayan E, Cohen LG. J. Cognitive Neuroscience, doi:10.1162/jocna00796 (2015)
Tissue- and time-dependent transcription in Ixodes ricinus salivary glands and midguts when blood feeding on the vertebrate host Kotsyfakis M, Schwarz A, Erhart J, Ribeiro JM Sci Rep, DOI://10.1038/srep09103 (2015)
Permutation Testing for Treatment-Covariate Interactions and Subgroup Identification Jared C. Foster, Bin Nan, Lei Shen, Niko Kaciroti, Jeremy M. G. Taylor Statistics in Bioscience, DOI 10.1007/s12561-015-9125-9 (2015)
Burden of Serious Infections in Adults With Systemic Lupus Erythematosus: A National Population-Based Study, 1996-2011 Maria G. Tektonidou, Zhong Wang, Abhijit Dasgupta and Michael M. Ward Arthritis Care and Research, DOI: 10.1002/acr.22575 (2015)

Synthesis and cell-selective antitumor properties of amino acid conjugated tumor-associated carbohydrate antigen-coated gold nanoparticles Biswas S, Medina SH, Barchi JJ Carbohydr. Res., DOI://10.1016/j.carres.2014.11.002 (2015)
Chromatin Architecture Reorganization during Stem Cell Differentiation Dixon JR, Jung I, Selvaraj S, Shen Y, Antosiewicz-Bourget JE, Lee AY, Ye Z, Kim A, Rajagopal N, Xie W, Diao Y, Liang J, Zhao H, Lobanenkov VV, Ecker JR, Thomson JA, Ren B Nature, doi: 10.1038/nature14222 (2015)
Dependence of Internal Friction on Folding Mechanism Wenwei Zheng, David De Sancho, Travis Hoppe, and Robert B. Best JACS, DOI: 10.1021/ja511609u (2015)
Mechanisms of Membrane Binding of Small GTPase K-Ras4B Farnesylated Hypervariable Region Hyunbum Jang, Sherwin J. Abraham, Tanmay S. Chavan, Ben Hitchinson, Lyuba Khavrutskii, Nadya I. Tarasova, Ruth Nussinov and Vadim Gaponenko J. Biol. Chem. , doi: 10.1074/jbc.M114.620724 (2015)
Predicting the Impact of Missense Mutations on Protein-Protein Binding Affinity Minghui Li, Marharyta Petukh, Emil Alexov, and Anna R. Panchenko J Chem Theory Comput., doi: 10.1021/ct401022c (2015)
Quantitative residue-specific protein backbone torsion angle dynamics from concerted measurement of 3J couplings Lee JH, Li F, Grishaev A, Bax A. J Am Chem Soc. , doi: 10.1021/ja512593s (2015)

Genome accessibility is widely preserved and locally modulated during mitosis Hsiung CC, Morrissey CS, Udugama M, Frank CL, Keller CA, Baek S, Giardine B, Crawford GE, Sung MH, Hardison RC, Blobel GA Genome Res. , doi: 10.1101/gr.180646 (2015)
Structure and dynamics of the fibronectin-III domains of Aplysia californica cell adhesion molecules Catherine M. Kelly , Julien Muzard , Bernard R. Brooks , Gil Lee and Nicolae-Viorel Buchete Phys. Chem. Chem. Phys., DOI: 10.1039/C4CP05307A (2015)
A Novel Tricyclic Ligand-Containing Nonpeptidic HIV-1 Protease Inhibitor, GRL-0739, Effectively Inhibits the Replication of Multidrug-Resistant HIV-1 Variants and Has a Desirable Central Nervous System Penetration Property In Vitro Masayuki Amano, Yasushi Tojo, Pedro Miguel Salcedo-Gòmez, Garth L. Parham, Prasanth R. Nyalapatla, Debananda Das, Arun K. Ghosh and Hiroaki Mitsuya Antimicrob Agents Chemother., doi: 10.1128/AAC.04757-14 (2015)
Identification of common genetic variants controlling transcript isoform variation in human whole blood Xiaoling Zhang, Roby Joehanes, Brian H Chen, Tianxiao Huan, Saixia Ying, Peter J Munson, Andrew D Johnson, Daniel Levy & Christopher J O'Donnell Nature Genetics, doi:10.1038/ng.3220 (2015)
Whole-genome sequencing to understand the genetic architecture of common gene expression and biomarker phenotypes Andrew R. Wood, Marcus A. Tuke, Mike Nalls et al. Hum Mol Genet., doi: 10.1093/hmg/ddu560 (2015)
Visualizing transient dark states by NMR spectroscopy Anthis NJ, Clore GM Q. Rev. Biophys., DOI://10.1017/S0033583514000122 (2015)

Functional MRI mapping of dynamic visual features during natural viewing in the macaque Russ BE, Leopold DA Neuroimage, DOI://10.1016/j.neuroimage.2015.01.012 (2015)
Analysis of the contribution of experimental bias, experimental noise, and inter-subject biological variability on the assessment of developmental trajectories in diffusion MRI studies of the brain Sadeghi, N; Nayak, A; Walker, L et al. Neuroimage, DOI://10.1016/j.neuroimage.2014.12.084 (2015)
Systems biology of polycystic kidney disease: a critical review Menezes LF, Germino GG Wiley Interdiscip Rev Syst Biol Med, DOI://10.1002/wsbm.1289 (2015)
High-Level Expression of Endo-β-N-Acetylglucosaminidase H from Streptomyces plicatus in Pichia pastoris and Its Application for the Deglycosylation of Glycoproteins Fei Wang, Xiaojuan Wang, Xiaolan Yu, Lin Fu, Yunyun Liu, Lixin Ma , Chao Zhai PLoS One, DOI: 10.1371/journal.pone.0120458 (2015)
A Genome-wide Association Study of Myasthenia Gravis Alan E. Renton, Hannah A. Pliner, Carlo Provenzano et al. JAMA Neurology, doi:10.1001/jamaneurol.2014.4103 (2015)
An Equilibrium Model for the Combined Effect of Macromolecular Crowding and Surface Adsorption on the Formation of Linear Protein Fibrils Travis Hoppe1, Allen P. Minton Biophys. J. , doi:10.1016/j.bpj.2014.12.033 (2015)

DNA methylation age of blood predicts all-cause mortality in later life Marioni, RE, Shah, S, McRae, AF, Chen, BH, Colicino, E, Harris, SE, Gibson, J, Henders, AK, Redmond, P, Cox, SR, Pattie, A, Corley, J, Murphy, L, Martin, NG, Montgomery, GW, Feinberg, AP, Fallin, M, Multhaup, ML, Jaffe, AE, Joehanes, R, Schwartz, J, Just, AC, Lunetta, KL, Murabito, JM, Starr, JM, Horvath, S, Baccarelli, AA, Levy, D, Visscher, PM, Wray, NR & Deary, IJ Genome Biology, doi://10.1186/s13059-015-0584-6 (2015)
Addressing population-specific multiple testing burdens in genetic association studies Sobota, RS; Shriner, D; Kodaman, N et al. Ann. Hum. Genet., DOI://10.1111/ahg.12095 (2015)
Stretch-Enhancers Delineate Disease-Associated Regulatory Nodes in T Cells Golnaz Vahedi, Yuka Kanno, Yasuko Furumoto, Kan Jiang, Stephen C. J. Parker, Michael R. Erdos, Sean R. Davis, Rahul Roychoudhuri, Nicholas P. Restifo, Massimo Gadina, Zhonghui Tang, Yijun Ruan, Francis S. Collins, Vittorio Sartorelli & John J. O'Shea Nature, doi:10.1038/nature14154 (2015)
Allosteric Effects of the Oncogenic RasQ61L Mutant on Raf-RBD. Fetics SK, Guterres H, Kearney BM, Buhrman G, Ma B, Nussinov R, Mattos C Structure, doi: 10.1016/j.str.2014.12.017 (2015)
Dynamics of chromatin accessibility and long-range interactions in response to glucocorticoid pulsing Stavreva DA, Coulon A, Baek S, Sung MH, John S, Stixova L, Tesikova M, Hakim O, Miranda T, Hawkins M, Stamatoyannopoulos JA, Chow CC, Hager GL Genome Res. , doi: 10.1101/gr.184168.114 (2015)
Role of contingency in striatal response to incentive in adolescents with anxiety Benson BE, Guyer AE, Nelson EE, Pine DS, Ernst M Cogn Affect Behav Neurosci, DOI://10.3758/s13415-014-0307-6 (2015)

The NAD(+)-dependent SIRT1 deacetylase translates a metabolic switch into regulatory epigenetics in skeletal muscle stem cells Ryall, JG; Dell'Orso, S; Derfoul, A et al. Cell Stem Cell, DOI://10.1016/j.stem.2014.12.004 (2015)
Efficient Data Mining for Local Binary Pattern in Texture Image Analysis Jin Tae Kwak, , Sheng Xu , Bradford J. Wood Expert Systems with Applications, doi:10.1016/j.eswa.2015.01.055 (2015)
What's Next for Next-Gen Sequencing? MaryAnn Labant Genetic Engineering and Biotechnology News, doi:10.1089/gen.35.03.02. (2015)
Vasopressin-responsive miRNAs and AQP2-targeting miRNAs in kidney collecting duct cells Jae-Eun Kim , Hyun Jun Jung , Yu-Jung Lee , Tae-Hwan Kwon Am. J. Physiol. - Renal Physiol., DOI: 10.1152/ajprenal.00334.2014 (2015)
A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins Guntur Fibriansah, Joanne L. Tan et al. Nature Communications, doi:10.1038/ncomms7341 (2015)
Design, Synthesis, and Application of Spinach Molecular Beacons Triggered by Strand Displacement Sanchita Bhadra, Andrew D. Ellington Methods in Enzymology, doi:10.1016/bs.mie.2014.10.049 (2015)

Transcriptional profiles reveal a stepwise developmental program of memory CD8(+) T cell differentiation Roychoudhuri, R; Lefebvre, F; Honda, M et al. Vaccine, DOI://10.1016/j.vaccine.2014.10.007 (2015)
Optimizing the order of hypotheses in serial testing of multiple endpoints in clinical trials. Zhang Z, Wang C, Troendle JF. Stat. Med., doi: 10.1002/sim.6425. (2015)
CENP-A nucleosomes localize to transcription factor hotspots and subtelomeric sites in human cancer cells Rajbir K Athwal, Marcin P Walkiewicz, Songjoon Baek, Song Fu, Minh Bui, Jordi Camps, Thomas Ried, Myong-Hee Sung and Yamini Dalal Epigenetics and Chromatin, doi:10.1186/1756-8935-8-2 (2015)
Coupled-Cluster Studies of Extensive Green Fluorescent Protein Models Using the Reduced Virtual Space Approach Robert Send , Carl-Mikael Suomivuori , Ville R. I. Kaila , and Dage Sundholm J. Phys. Chem. B, DOI: 10.1021/jp5120898 (2015)
Myosin II controls cellular branching morphogenesis and migration in three dimensions by minimizing cell-surface curvature Elliott, H; Fischer, RS; Myers, KA et al. Nat. Cell Biol., DOI://10.1038/ncb3092 (2015)
Withdrawal from long-term methamphetamine self-administration 'normalizes' neurometabolites in rhesus monkeys: a (1) H MR spectroscopy study Yang S, Belcher AM, Chefer S, Vaupel DB, Schindler CW, Stein EA, Yang Y. Addict Biol., doi: 10.1111/adb.12078. (2015)

Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma Shakhova, O; Cheng, P; Mishra, PJ et al. PLoS Genet., DOI://10.1371/journal.pgen.1004877 (2015)
Molecular basis of the polyspecificity of P-glycoprotein (ABCB1): recent biochemical and structural studies Chufan EE, Sim HM, Ambudkar SV Adv Cancer Res, doi: 10.1016/bs.acr.2014.10.003 (2015)
fMRI functional connectivity applied to adolescent neurodevelopment Ernst M, Torrisi S, Balderston N, Grillon C, Hale EA. Annu Rev Clin Psychol., doi: 10.1146/annurev-clinpsy-032814-112753 (2015)
A systematic heritability analysis of the human whole blood transcriptome. Huan T, Liu C, Joehanes R, Zhang X, Chen BH, Johnson AD, Yao C, Courchesne P, O'Donnell CJ, Munson PJ, Levy D. Human Genetics (2015)
Detecting Functional Connectivity during Audiovisual Integration with MEG: a Comparison of Connectivity Metrics. Ard TD, Carver F, Holroyd T, Horwitz B, Coppola R. Brain Connect. (2015)
Cerebro-cerebellar connectivity is increased in primary lateral sclerosis Meoded A, Morrissette AE, Katipally R, Schanz O, Gotts SJ, Floeter MK Neuroimage Clin, DOI://10.1016/j.nicl.2014.12.009 (2015)

Functional mapping of face-selective regions in the extrastriate visual cortex of the marmoset Hung, CC; Yen, CC; Ciuchta, JL et al. J. Neurosci., DOI://10.1523/JNEUROSCI.2659-14.2015 (2015)
Modulation of Alzheimer's Aβ protofilament-membrane interactions by lipid headgroups. Tofoleanu F, Brooks BR, Buchete NV. ACS Chem Neurosci., doi://abs/10.1021/cn500277f (2015)
Insights into the Mechanism of Inhibition of CXCR4: Identification of Piperidinylethanamine Analogs as Anti-HIV-1 Inhibitors Das D, Maeda K, Hayashi Y, Gavande N, Desai DV, Chang SB, Ghosh AK, Mitsuya H Antimicrob Agents Chemother., pii: AAC.04654-14. (2015)
Variable selection method for the identification of epistatic models Holzinger ER, Szymczak S, Dasgupta A, Malley J, Li Q, Bailey-Wilson JE Pac Symp Biocomput, 2335-6936 (2015)
CDD: NCBI's conserved domain database Marchler-Bauer, A; Derbyshire, MK; Gonzales, NR et al. Nucleic Acids Res., DOI://10.1093/nar/gku1221 (2015)
Analysis of soluble protein entry into primary cilia using semipermeabilized cells David K. Breslow, Maxence V. Nachury Methods in Cell Biology, doi:10.1016/bs.mcb.2014.12.006 (2015)

NRG1, ERBB4 and AKT1 Epistasis Increases Schizophrenia Risk and is Biologically Validated via Functional Neuroimaging in Healthy Controls Nicodemus KK, Law AJ, Radulescu E, Luna A, Kolachana B, Vakkalanka R, Rujescu D, Giegling I, Straub RE, McGee K, Gold B, Dean M, Muglia P, Callicott JH, Tan HY, Weinberger DR. Arch Gen Psychiatry, doi: 10.1001/archgenpsychiatry.2010.117 (2015)
Maturation of the HIV-1 core by a non-diffusional phase transition Frank GA, Narayan K, Bess JW Jr, Del Prete GQ, Wu X, Moran A, Hartnell LM, Earl LA, Lifson JD, Subramaniam S Nature Communications, doi: 10.1038/ncomms6854 (2015)
Meta-analysis of Correlated Traits via Summary Statistics from GWASs with an Application in Hypertension Xiaofeng Zhu, Tao Feng, Bamidele O. Tayo et al. Am J Hum Genet., doi: 10.1016/j.ajhg.2014.11.011. (2015)
Protein structural information derived from NMR chemical shift with the neural network program TALOS-N Shen Y, Bax A Methods Mol. Biol., DOI://10.1007/978-1-4939-2239-0_2 (2015)
BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones Kanno T, Kanno Y, LeRoy G, Campos E, Sun HW, Brooks SR, Vahedi G, Heightman TD, Garcia BA, Reinberg D, Siebenlist U, O'Shea JJ, Ozato K Nat Struct Mol Biol., doi: 10.1038/nsmb.2912 (2015)
Structures of oxalate oxidoreductase : C₂ activation by a microbial TPP-dependent ferredoxin oxidoreductase Gibson, Marcus Ian PhD Thesis, MIT Dept of Chemistry (2015)

2014 (190 papers)

Telomere attrition and candidate gene mutations preceding monosomy 7 in aplastic anemia. Dumitriu B, Feng X, Townsley DM, Ueda Y, Yoshizato T, Calado RT, Yang Y, Wakabayashi Y, Kajigaya S, Ogawa S, Zhu J, Young NS Blood, doi://10.1182/blood-2014-10-607572 (2014)
Polymorphism in Self-Assembly of Peptide-Based β-Hairpin Contributes to Network Morphology and Hydrogel Mechanical Rigidity Yifat Miller, Buyong Ma, and Ruth Nussinov J. Phys. Chem. B, DOI: 10.1021/jp511485n (2014)
Prospective Associations of Coronary Heart Disease Loci in African Americans Using the MetaboChip: The PAGE Study Nora Franceschini, Yijuan Hu, Alex P. Reiner, et al. PLoS One, DOI: 10.1371/journal.pone.0113203 (2014)
Behçet disease-associated MHC class I residues implicate antigen binding and regulation of cell-mediated cytotoxicity. Ombrello MJ, Kirino Y, de Bakker PI, Gül A, Kastner DL, Remmers EF PNAS, doi: 10.1073/pnas.1406575111 (2014)
Integrated transcriptome analysis of mouse spermatogenesis Margolin G, Khil PP, Kim J, Bellani MA, Camerini-Otero RD BMC Genomics, doi: 10.1186/1471-2164-15-39 (2014)
Integromic Analysis of Genetic Variation and Gene Expression Identifies Networks for Cardiovascular Disease Phenotypes Chen Yao, Brian H. Chen, Roby Joehanes, et al. Circulation, doi: 10.1161/CIRCULATIONAHA.114.010696 (2014)

Sex- and Tissue-Specific Functions of Drosophila Doublesex Transcription Factor Target Genes Clough E, Jimenez E, Kim YA, Whitworth C, Neville MC, Hempel LU, Pavlou HJ, Chen ZX, Sturgill D, Dale RK, Smith HE, Przytycka TM, Goodwin SF, Van Doren M, Oliver B Dev. Cell, doi: 10.1016/j.devcel.2014.11.021 (2014)
Leveraging Local identity-by-descent increases the power of Case/Control GWAS with Related Individuals Joshua N Sampson, Bill Wheeler, Peng Li, Jianxin Shi Ann Appl Stat. 8(2):974-998. (2014)
Genome sequencing accuracy by RCA-seq versus long PCR template cloning and sequencing in identification of human papillomavirus type 58 Wang X, Li Y, Ni T, Xie X, Zhu J, Zheng ZM Cell Biosci. , doi: 10.1186/2045-3701-4-5 (2014)
Complex interactions of transcription factors in mediating cytokine biology in T cells Li P, Spolski R, Liao W, Leonard WJ. Immunol Rev, doi: 10.1111/imr.12199. (2014)
Opposing actions of IL-2 and IL-21 on Th9 differentiation correlate with their differential regulation of BCL6 expression Liao W, Spolski R, Li P, Du N, West EE, Ren M, Mitra S, Leonard WJ. PNAS, doi: 10.1073/pnas.1301138111 (2014)
Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo. Rudicell RS1, Kwon YD, Ko SY et al. Journal of Virology, doi: 10.1128/JVI.02213-14 (2014)

High Accuracy of Karplus Equations for Relating Three-Bond J Couplings to Protein Backbone Torsion Angles Fang Li, Jung Ho Lee, Alexander Grishaev, Jinfa Ying and Ad Bax Eur. J. Chem. Phys. Chem. , DOI: 10.1002/cphc.201402704 (2014)
Challenges and solutions for gene identification in the presence of familial locus heterogeneity Atteeq U Rehman, Regie Lyn P Santos-Cortez et al. Eur. J. Human Genetics, doi: 10.1038/ejhg.2014.266 (2014)
Linear Energy Relationships in Ground State Proton Transfer and Excited State Proton-Coupled Electron Transfer Ana-Patricia Gàmiz-Hernàndez , Artiom Magomedov , Gerhard Hummer , and Ville R. I. Kaila J. Phys. Chem. B, DOI: 10.1021/jp508790n (2014)
B Cell Super-Enhancers and Regulatory Clusters Recruit AID Tumorigenic Activity Jason Qian, Qiao Wang, Marei Dose et al. Cell, doi:10.1016/j.cell.2014.11.013 (2014)
Free energies from dynamic weighted histogram analysis using unbiased Markov state model Edina Rosta and Gerhard Hummer J. Chem. Theory Comput., DOI: 10.1021/ct500719p (2014)
High-resolution genome-wide DNA methylation maps of mouse primary female dermal fibroblasts and keratinocytes Raghunath Chatterjee, Ximiao He, Di Huang, Peter Fitzgerald, Andrew Smith and Charles Vinson Epigenetics and Chromatin, doi:10.1186/1756-8935-7-35 (2014)

Nucleosomes are enriched at the boundaries of hypomethylated regions (HMRs) in mouse dermal fibroblasts and keratinocytes Ximiao He, Raghunath Chatterjee, Desiree Tillo, Andrew Smith, Peter FitzGerald and Charles Vinson Epigenetics and Chromatin, doi:10.1186/1756-8935-7-34 (2014)
Genetic diversity is a predictor of mortality in humans Bihlmeyer NA, Brody JA, et al. BMC Genetics, doi:10.1186/s12863-014-0159-7 (2014)
TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4(+) T cell fate and interact with Runx3 to silence Cd4 in CD8(+) T cells Steinke FC, Yu S, Zhou X, He B, Yang W, Zhou B, Kawamoto H, Zhu J, Tan K8, Xue HH Naturesteinc Immunol. , doi: 10.1038/ni.2897. (2014)
Brain Structural Substrates of Reward Dependence during Behavioral Performance Dayan E, Hamann JM, Averbeck BB, Cohen LG J. Neurosci. , doi: 10.1523/JNEUROSCI.3141-14.2014 (2014)
Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2 Zhou Q, Yang D, Ombrello AK, et al. N. Engl. J. Med. , doi: 10.1056/NEJMoa1307361 (2014)
Modern perspectives on numerical modeling of cardiac pacemaker cell Maltsev VA, Yaniv Y, Maltsev AV, Stern MD, Lakatta EG J. Pharmacological Sci. , doi://10.1254/jphs.13R04CR (2014)

Risk estimation using probability machines. Dasgupta A1, Szymczak S, Moore JH, Bailey-Wilson JE, Malley JD BioData Min. , doi: 10.1186/1756-0381-7-2. (2014)
Rbfox3 controls the biogenesis of a subset of microRNAs Kim KK, Yang Y, Zhu J, Adelstein RS, Kawamoto S. Nat Struct Mol Biol., doi: 10.1038/nsmb.2892 (2014)
Bayesian analysis of individual electron microscopy images: Towards structures of dynamic and heterogeneous biomolecular assemblies Pilar Cossio and Gerhard Hummer J Struct Biol. , doi: 10.1016/j.jsb.2013.10.006 (2014)
Valence-specific effects of BDNF Val66Met polymorphism on dopaminergic stress and reward processing in humans Peciña M, Martìnez-Jauand M, Love T, Heffernan J, Montoya P, Hodgkinson C, Stohler CS, Goldman D, Zubieta JK. J. Neurosci., doi: 10.1523/JNEUROSCI.2152-13 (2014)
Comparative phosphoproteomic analysis of mammalian glomeruli reveals conserved podocin C-terminal phosphorylation as a determinant of slit diaphragm complex architecture Markus M. Rinschen, Caroline Pahmeyer, Trairak Pisitkun, Nicole Schnell, Xiongwu Wu, Martina Maa, Malte P. Bartram, Tobias Lamkemeyer, Bernhard Schermer, Thomas Benzing andPaul T. Brinkkoetter Proteomics, DOI: 10.1002/pmic.201400235 (2014)
A Systems Genetics Approach Identifies CXCL14, ITGAX, and LPCAT2 as Novel Aggressive Prostate Cancer Susceptibility Genes Kendra A. Williams, Minnkyong Lee, Ying Hu et al. PLoS Genetics, doi: 10.1371/journal.pgen.1004809 (2014)

Charge Neutralization of the Central Lysine Cluster in Prion Protein (PrP) Promotes PrPSc-Like Folding of Recombinant PrP Amyloids Bradley R. Groveman, Allison Kraus, Lynne D. Raymond, Michael A. Dolan, Kelsie J. Anson, David W. Dorward and Byron Caughey J. Biol. Chem. , doi: 10.1074/jbc.M114.619627 (2014)
Pathogenic Ischemic Stroke Phenotypes in the NINDS-Stroke Genetics Network Hakan Ay, Ethem Murat Arsava et al. Stroke, doi: 10.1161/STROKEAHA.114.007362 (2014)
Variant GADL1 and response to lithium in bipolar I disorder Consortium on Lithium Genetics, Hou L, Heilbronner U, Rietschel M, Kato T, Kuo PH, McMahon FJ, Schulze TG. N. Engl. J. Med. , doi: 10.1056/NEJMc1401817#SA4 (2014)
Investigation of the interactions between the EphB2 receptor and SNEW peptide variants Buyong Ma, Stephanie Kolb, Michael Diprima, Molleshree Karna, Giovanna Tosato, Qiqi Yang, Qiang Huang, and Ruth Nussinov Growth Factors, DOI: 10.3109/08977194.2014.985786 (2014)
Self-assembled monolayers improve protein distribution on holey carbon cryo-EM supports Joel R. Meyerson, Prashant Rao, Janesh Kumar, Sagar Chittori, Soojay Banerjee, Jason Pierson, Mark L. Mayer & Sriram Subramaniam Nature, doi:10.1038/srep07084 (2014)
Diversity and dynamics of the Drosophila transcriptome. Brown JB, Boley N, Eisman R, May GE et al Nature, doi:10.1038/nature12962 (2014)

Database of osmoregulated proteins in mammalian cells Cameron R. Grady , Mark A. Knepper , Maurice B. Burg , Joan D. Ferraris Physiological Reports, DOI: 10.14814/phy2.12180 (2014)
Simple subgroup approximations to optimal treatment regimes from randomized clinical trial data Jared C. Foster, Jeremy M.G. Taylor, Niko Kaciroti and Bin Nan Biostatistics, doi: 10.1093/biostatistics/kxu049 (2014)
Mitochondrial DNA Sequence Variation Associated With Peripheral Nerve Function in the Elderly Shana M. Katzman, Elsa S. Strotmeyer, Michael A. Nalls et al. J. Gerontology A, doi: 10.1093/gerona/glu175 (2014)
Role of solvation in pressure-induced helix stabilization Robert B. Best, Cayla Miller and Jeetain Mittal J. Chem. Physics, doi:///10.1063/1.4901112 (2014)
Mass spectrometry based protein identification with accurate statistical significance assignment Gelio Alves and Yi-Kuo Yu Bioinformatics, doi: 10.1093/bioinformatics/btu717 (2014)
Modeling vocalization with ECoG cortical activity recorded during vocal production in the macaque monkey Makoto Fukushima, Richard C Saunders, Naotaka Fujii, Bruno B Averbeck, Mortimer Mishkin Engineering in Medicine and Biology, DOI://10.1109/EMBC.2014.6945188 (2014)

DNA recombination. Recombination initiation maps of individual human genomes Pratto, F; Brick, K; Khil, P; Smagulova, F; Petukhova, GV; Camerini-Otero, RD; Science, DOI://10.1126/science.1256442 (2014)
Development and Implementation of (Q)SAR Modeling Within the CHARMMing Web-User Interface Iwona E. Weidlich, Yuri Pevzner, Benjamin T. Miller, Igor V. Filippov, H. Lee Woodcock, and Bernard R. Brooks J. Comp. Chem., DOI: 10.1002/jcc.23765 (2014)
Master Regulators, Regulatory Networks, and Pathways of Glioblastoma Subtypes Serdar Bozdag, Aiguo Li, Mehmet Baysan, and Howard A Fine Cancer Informatics, doi: 10.4137/CIN.S14027 (2014)
Variants associated with type 2 diabetes identified by the transethnic meta-analysis study: assessment in American Indians and evidence for a new signal in LPP Nair AK, Muller YL, McLean NA, Abdussamad M, Piaggi P, Kobes S, Weil EJ, Curtis JM, Nelson RG, Knowler WC, Hanson RL, Baier LJ Diabetologia, doi: 10.1007/s00125-014-3351-4 (2014)
DLX3 regulates bone mass by targeting genes supporting osteoblast differentiation and mineral homeostasis in vivo Isaac J, Erthal J, Gordon J, Duverger O, Sun HW, Lichtler AC, Stein GS, Lian JB, Morasso MI Cell Death Differ. , doi: 10.1038/cdd.2014.82 (2014)
Human syndromes of immunodeficiency and dysregulation are characterized by distinct defects in T-cell receptor repertoire development. Yu X, Almeida JR2, Darko S et al. J Allergy Clin Immunol., doi: 10.1016/j.jaci.2013.11.018. (2014)

Autosomal recessive phosphoglucomutase 3 (PGM3) mutations link glycosylation defects to atopy, immune deficiency, autoimmunity, and neurocognitive impairment. Zhang Y, Yu X, Ichikawa M et al. J Allergy Clin Immunol. , doi: 10.1016/j.jaci.2014.02.013 (2014)
FAAH selectively influences placebo effects Peciña M, Martìnez-Jauand M, Hodgkinson C, Stohler CS, Goldman D, Zubieta JK Molecular Psychiatry, doi: 10.1038/mp.2013.124 (2014)
Essential dynamics analysis captures the concerted motion of the integrin-binding site in jerdostatin, an RTS disintegrin Luisa Calvanese, Lucia Falcigno andGabriella D'Auria Biopolymers, DOI: 10.1002/bip.22578 (2014)
Role of the Fast Kinetics of Pyroglutamate-Modified Amyloid-β Oligomers in Membrane Binding and Membrane Permeability Joon Lee, Alan L. Gillman, Hyunbum Jang, Srinivasan Ramachandran, Bruce L. Kagan, Ruth Nussinov, Fernando Teran Arce Biochemistry, doi: 10.1021/bi500587p (2014)
Pathogenic Properties of Alzheimer's β-Amyloid Identified from Structure-Property Patient-Phenotype Correlations Manish K. Tiwari and Kasper P. Kepp Dalt. Transac. , DOI: 10.1039/C4DT03122A (2014)
Using fMRI to decode true thoughts independent of intention to conceal Yang Z, Huang Z, Gonzalez-Castillo J, Dai R, Northoff G, Bandettini P NeuroImage, doi: 10.1016/j.neuroimage.2014.05.034 (2014)

Probing the Flexibility of Tropomyosin and Its Binding to Filamentous Actin Using Molecular Dynamics Simulations Wenjun Zheng, Bipasha Barua, and Sarah E. Hitchcock-DeGregori Biophysical J. , doi: 10.1016/j.bpj.2013.09.003 (2014)
Cohesin-dependent globules and heterochromatin shape 3D genome architecture in S. pombe Takeshi Mizuguchi, Geoffrey Fudenberg, Sameet Mehta, Jon-Matthew Belton, Nitika Taneja, Hernan Diego Folco, Peter FitzGerald, Job Dekker, Leonid Mirny, Jemima Barrowman & Shiv I. S. Grewal Nature, doi:10.1038/nature13833 (2014)
Direct Evidence for a Peroxide Intermediate and a Reactive Enzyme-Substrate-Dioxygen Configuration in a Cofactor-free Oxidase Soi Bui, David von Stetten, Pablo G. Jambrina, Thierry Prangé, Nathalie Colloc'h, Daniele de Sanctis, Antoine Royant, Edina Rosta and Roberto A. Steiner Angewandte Chemie, DOI: 10.1002/anie.201405485 (2014)
Sequential monte carlo tracking of the marginal artery by multiple cue fusion and random forest regression Kevin M. Cherry, Brandon Peplinski, Lauren Kim, Shijun Wang, Le Lu, Weidong Zhang, Jianfei Liu, Zhuoshi Wei, Ronald M. Summers Medical Image Analysis, DOI: 10.1016/j.media.2014.09.006 (2014)
Balanced Protein-Water Interactions Improve Properties of Disordered Proteins and Non-Specific Protein Association Robert B. Best, Wenwei Zheng, and Jeetain Mittal J. Chem. Theory and Computation, DOI: 10.1021/ct500569b (2014)
Phactr3/Scapinin, a Member of Protein Phosphatase 1 and Actin Regulator (Phactr) Family, Interacts with the Plasma Membrane via Basic and Hydrophobic Residues in the N-Terminus Akihiro Itoh, Atsushi Uchiyama, Shunichiro Taniguchi, and Junji Sagara PLoS One, doi: 10.1371/journal.pone.0113289 (2014)
Crystal structure of a c-di-AMP riboswitch reveals an internally pseudo-dimeric RNA Christopher P Jones andAdrian R Ferr�-D'Amarè EMBO J., DOI: 10.15252/embj.201489209 (2014)
A system for multilocus chromosomal integration and transformation-free selection marker rescue Michael S. Siddiqui, Atri Choksi andChristina D. Smolke Yeast Research, DOI: 10.1111/1567-1364.12210 (2014)
Biogeography and individuality shape function in the human skin metagenome Julia Oh, Allyson L. Byrd, Clay Deming, Sean Conlan, NISC Comparative Sequencing Program, Heidi H. Kong & Julia A. Segre Nature, doi:10.1038/nature13786 (2014)
Combining one-sample confidence procedures for inference in the two-sample case Michael P. Fay, Michael A. Proschan andErica Brittain Biometrics, DOI: 10.1111/biom.12231 (2014)
Certain adenylated non-coding RNAs, including 5' leader sequences of primary microRNA transcripts, accumulate in mouse cells following depletion of the RNA helicase MTR4 Dorweiler JE, Ni T, Zhu J, Munroe SH, Anderson JT PLoS One, doi: 10.1371/journal.pone.0099430. (2014)
miR-191 and miR-135 are required for long-lasting spine remodelling associated with synaptic long-term depression Hu Z, Yu D, Gu QH, Yang Y, Tu K, Zhu J, Li Z Nature Communications, doi: 10.1038/ncomms4263 (2014)
Determination of the allelic frequency in Smith-Lemli-Opitz syndrome by analysis of massively parallel sequencing data sets Cross JL, Iben J, Simpson CL, Thurm A, Swedo S, Tierney E, Bailey-Wilson JE, Biesecker LG, Porter FD, Wassif CA Clin. Genet. , doi: 10.1111/cge.12425. (2014)
Activated STING in a Vascular and Pulmonary Syndrome Liu Y, Jesus AA, Marrero B et al. New England J. Medicine, doi: 10.1056/NEJMoa1312625. (2014)
An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome Scott W Canna, Adriana A de Jesus, Sushanth Gouni, Stephen R Brooks, Bernadette Marrero, Yin Liu, Michael A DiMattia, Kristien J M Zaal, Gina A Montealegre Sanchez, Hanna Kim, Dawn Chapelle, Nicole Plass, Yan Huang, Alejandro V Villarino, Angelique Biancotto, Thomas A Fleisher, Joseph A Duncan, John J O'Shea, Susanne Benseler, Alexei Grom, Zuoming Deng, Ronald M Laxer & Raphaela Goldbach-Mansky Nature Genetics, doi:10.1038/ng.3089 (2014)
DNA copy number evolution in Drosophila cell lines Hangnoh Lee, C Joel McManus et al. Genome Biology, doi:10.1186/gb-2014-15-8-r70 (2014)
Joint analysis of longitudinal and survival data measured on nested timescales by using shared parameter models: an application to fecundity data Alexander C. McLain, Rajeshwari Sundaram and Germaine M. Buck Louis Applied Statistics, DOI: 10.1111/rssc.12075 (2014)
DNase Footprint Signatures Are Dictated by Factor Dynamics and DNA Sequence Myong-Hee Sung, Michael J. Guertin, Songjoon Baek, Gordon L. Hager Molecular Cell, DOI: 10.1016/j.molcel.2014.08.016 (2014)

Correcting for the free energy costs of bond or angle constraints in molecular dynamics simulations Gerhard König, , Bernard R. Brooks Biochim. et Biophys. Acta, DOI: 10.1016/j.bbagen.2014.09.001 (2014)
Genetic polymorphisms in the 9p21 region associated with risk of multiple cancers Wen-Qing Li, Ruth M. Pfeiffer, Paula L. Hyland, Jianxin Shi, Fangyi Gu, Zhaoming Wang, Samsiddhi Bhattacharjee, Jun Luo, Xiaoqin Xiong, Meredith Yeager, Xiang Deng, Nan Hu, Philip R. Taylor, Demetrius Albanes, Neil E. Caporaso, Susan M. Gapstur, Laufey Amundadottir, Stephen J. Chanock, Nilanjan Chatterjee, Maria Teresa Landi, Margaret A. Tucker, Alisa M. Goldstein and Xiaohong R. Yang Carcinogenesis, doi: 10.1093/carcin/bgu203 (2014)
Enhanced expression of the codon-optimized exo-inulinase gene from the yeast Meyerozyma guilliermondii in Saccharomyces sp. W0 and bioethanol production from inulin Guang-Lei Liu, Ge-Yi Fu, Zhe Chi and Zhen-Ming Chi Bioenergy and Biofuels, doi://10.1007/s00253-014-6079-7 (2014)
Efficiently computing pathway free energies: New approaches based on chain-of-replica and Non-Boltzmann Bennett reweighting schemes Phillip S. Hudson, Justin K. White, Fiona L. Kearns, Milan Hodoscek, Stefan Boresch, H. Lee Woodcock Biochim. et Biophys. Acta, DOI: 10.1016/j.bbagen.2014.09.016 (2014)
Common genetic variation in and near the melanocortin 4 receptor gene (MC4R) is associated with body mass index in American Indian adults and children. Muller YL, Thearle MS, Piaggi P, Hanson RL, Hoffman D, Gene B, Mahkee D, Huang K, Kobes S, Votruba S, Knowler WC, Bogardus C, Baier LJ. Human Genetics, doi://10.1007/s00439-014-1477-6 (2014)
Neuronal or hemodynamic? Grappling with the functional MRI signal Bandettini PA Brain Connect, doi: 10.1089/brain.2014.0288. (2014)

A knowledge base of vasopressin actions in the kidney Akshay Sanghi, Matthew Zaringhalam, Callan C Corcoran, Fahad Saeed, Jason D. Hoffert, Pablo C Sandoval, Trairak Pisitkun, Mark A. Knepper Am. J. Physiol. - Renal Physiol., DOI: 10.1152/ajprenal.00012.2014 (2014)
Generalized Functional Linear Models for Gene-Based Case-Control Association Studies Ruzong Fan, Yifan Wang, James L. Mills, Tonia C. Carter, Iryna Lobach, Alexander F. Wilson, Joan E. Bailey-Wilson, Daniel E. Weeks and Momiao Xiong Genetic Epidemiology, DOI: 10.1002/gepi.21840 (2014)
Conformational dynamics and aggregation behavior of piezoelectric diphenylalanine peptides in an external electric field Catherine M. Kelly, Thomas Northey, Kate Ryan, Bernard R. Brooks, Andrei Kholkin, Brian J. Rodriguez, Nicolae-Viorel Buchete Biophysical Chemistry, DOI: 10.1016/j.bpc.2014.08.009 (2014)
Free-Propagator Reweighting Integrator for Single-Particle Dynamics in Reaction-Diffusion Models of Heterogeneous Protein-Protein Interaction Systems Margaret Johnson and Gerhard Hummer Physical Review X, DOI: 10.1103/PhysRevX.4.031037 (2014)
metaseq: a Python package for integrative genome-wide analysis reveals relationships between chromatin insulators and associated nuclear mRNA Dale RK, Matzat LH, Lei EP Nucleic Acids Research, doi: 10.1093/nar/gku644 (2014)
Deletion of aryl hydrocarbon receptor AHR in mice leads to subretinal accumulation of microglia and RPE atrophy Soo-Young Kim, Hyun-Jin Yang, Yi-Sheng Chang, Jung-woong Kim, Matthew Brooks, Emily Y. Chew, Wai T. Wong, Robert Fariss, Rivka Rachel, Tiziana Cogliati, Haohua Qian and Anand Swaroop Investigative Opthalmology and Visual Science, doi: 10.1167/iovs.14-15091 (2014)

Modeling longitudinal data with a random change point and no time-zero: Applications to inference and prediction of the labor curve Alexander C. McLain and Paul S. Albert Biometrics, DOI: 10.1111/biom.12218 (2014)
Molecular origins of internal friction effects on protein-folding rates de Sancho D, Sirur A, Best RB Nature Communications, doi: 10.1038/ncomms5307 (2014)
Design and rationale for a genome-wide association study of ischemic stroke subtypes James F. Meschia, Donna K. Arnett, Hakan Ay et al. Stroke, doi: 10.1161/STROKEAHA.113.001857 (2014)
Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations Chen Wu, Zhaoming Wang, Xin Song et al. Nature Genetics, doi:10.1038/ng.3064 (2014)
Systematic Genetic Analysis Identifies Cis-eQTL Target Genes Associated with Glioblastoma Patient Survival Qing-Rong Chen, Ying Hu, Chunhua Yan, Kenneth Buetow, Daoud Meerzaman PLoS One, DOI: 10.1371/journal.pone.0105393 (2014)
Structural Insight into Tau Protein's Paradox of Intrinsically Disordered Behavior, Self-Acetylation Activity, and Aggregation Yin Luo, Buyong Ma, Ruth Nussinov, and Guanghong Wei J. Phys. Chem. Lett, DOI: 10.1021/jz501457f (2014)

Impaired corticopontocerebellar tracts underlie pseudobulbar affect in motor neuron disorders Mary Kay Floeter, Rohan Katipally, Meredith P. Kim, Olivia Schanz, Matthew Stephen, Laura Danielian, Tianxia Wu, Edward D. Huey, and Avner Meoded Neurology, doi: 10.1212/WNL.0000000000000693 (2014)
Programmable Nanoscaffolds that Control Ligand Display to a G Protein Coupled-Receptor in Membranes allow Dissection of Multivalent Effects Andrew V. Dix, Steven M Moss, Khai Phan, Travis Hoppe, Silvia Paoletta, Eszter Kozma, Zhan-Guo Gao, Stewart R. Durell, Kenneth A. Jacobson, and Daniel H. Appella J. Am. Chem. Soc. , DOI: 10.1021/ja504288s (2014)
Identification of Three Noncontiguous Regions on Bacillus anthracis Plasmid pXO1 That Are Important for Its Maintenance Andrei P. Pomerantsev, Zanetta Chang, Catherine Rappole and Stephen H. Leppla J. Bacteriology, doi: 10.1128/JB.01747-14 (2014)
Random Single Amino Acid Deletion Sampling Unveils Structural Tolerance and the Benefits of Helical Registry Shift on GFP Folding and Structure James A.J. Arpino, Samuel C. Reddington, Lisa M. Halliwell, Pierre J. Rizkallah, D. Dafydd Jones Structure, DOI: 10.1016/j.str.2014.03.014 (2014)
Optimizing area under the ROC curve using semi-supervised learning Shijun Wang, Diana Li, Nicholas Petrick, Berkman Sahiner, Marius George Linguraru, Ronald M. Summers Pattern Recognition, DOI: 10.1016/j.patcog.2014.07.025 (2014)
Trans-ethnic Meta-analysis of White Blood Cell Phenotypes MF Keller, AP Reiner et al. Human Molecular Genetics, doi://10.1093/hmg/ddu401 (2014)

NeuroX, a Fast and Efficient Genotyping Platform for Investigation of Neurodegenerative Diseases Mike A. Nalls, Jose Bras, Dena G. Hernandez, et al. Neurobiology of Aging, DOI: 10.1016/j.neurobiolaging.2014.07.028 (2014)
A Novel MMP12 Locus Is Associated with Large Artery Atherosclerotic Stroke Using a Genome-Wide Age-at-Onset Informed Approach Traylor M et al. PLoS Genetics, DOI: 10.1371/journal.pgen.1004469 (2014)
Structural mechanism of glutamate receptor activation and desensitization Joel R. Meyerson, Janesh Kumar, Sagar Chittori, Prashant Rao, Jason Pierson, Alberto Bartesaghi, Mark L. Mayer & Sriram Subramaniam Nature, doi:10.1038/nature13603 (2014)
Structure of β-galactosidase at 3.2-Å resolution obtained by cryo-electron microscopy Alberto Bartesaghi, Doreen Matthies, Soojay Banerjee, Alan Merk, and Sriram Subramaniam PNAS, doi://10.1073/pnas.1402809111 (2014)
Dynamics differentiate between active and inactive inteins Melissa Cronin, Michael J. Coolbaug, David Nellis, Jianwei Zhu, David W. Wood, Ruth Nussinov, Buyong Ma Eur. J. Med. Chem., DOI: 10.1016/j.ejmech.2014.07.094 (2014)
Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease MA Nalls, N Pankratz, CM Lill et al. Nature Genetics, doi:10.1038/ng.3043 (2014)

Differentiating BOLD and non-BOLD signals in fMRI time series from anesthetized rats using multi-echo EPI at 11.7T Prantik Kundu, Mathieu D. Santin, Peter A. Bandettini, Edward T. Bullmore, Alexandra Petiet NeuroImage, DOI: 10.1016/j.neuroimage.2014.07.025 (2014)
A robust association test for detecting genetic variants with heterogeneous effects Kai Yu and Han Zhang Biostatistics, doi: 10.1093/biostatistics/kxu036 (2014)
Image-Guided Synthesis Reveals Potent Blood-Brain Barrier Permeable Histone Deacetylase Inhibitors Young Jun Seo, Yeona Kang, Lisa Muench, Alicia Reid, Shannon Caesar, Logan Jean, Florence Wagner, Edward Holson, Stephen J. Haggarty, Philipp Weiss, Payton King, Pauline Carter, Nora D. Volkow, Joanna S. Fowler, Jacob M. Hooker, and Sung Won Kim ACS Chemical Neurosciene, DOI: 10.1021/cn500021p (2014)
Structural Basis of hAT Transposon End Recognition by Hermes, an Octameric DNA Transposase from Musca domestica Alison B. Hickman, Hosam E. Ewis, Xianghong Li, Joshua A. Knapp, Thomas Laver, Anna-Louise Doss, Gökhan Tolun, Alasdair C. Steven, Alexander Grishaev, Ad Bax, Peter W. Atkinson, Nancy L. Craig, Fred Dyda Cell, DOI: 10.1016/j.cell.2014.05.037 (2014)
Parallel in-register intermolecular β-sheet architectures for prion seeded PrP amyloids Bradley R. Groveman, Michael A. Dolan, Lara M. Taubner, Allison Kraus, Reed B. Wickner and Byron Caughey J. Biol. Chem. , doi: 10.1074/jbc.M114.578344 (2014)
The Three Mycobacterium Tuberculosis Antigen 85 Isoforms have Unique Substrates and Activities Determined by Non-active Site Regions Keriann M. Backus, Michael A. Dolan, Conor S. Barry, Maju Joe, Peter McPhie, Helena I.M. Boshoff, Todd L. Lowary, Benjamin G. Davis and Clifton E. Barry III J. Biol. Chem. , doi: 10.1074/jbc.M114.581579 (2014)

Accounting for length-bias and selection effects in estimating the distribution of menstrual cycle length Kirsten J. Lum, Rajeshwari Sundaram, Thomas A. Louis Biostatistics, doi: 10.1093/biostatistics/kxu035 (2014)
Genome-Wide Analysis of the Heritability of Amyotrophic Lateral Sclerosis MF Keller, L Ferrucci, AB Singleton et al. JAMA Neurology, doi:10.1001/jamaneurol.2014.1184 (2014)
The Genomic Landscape of the Ewing Sarcoma Family of Tumors Reveals Recurrent STAG2 Mutation Andrew S. Brohl, David A. Solomon, Wendy Chang et al. PLoS Genetics, DOI: 10.1371/journal.pgen.1004475 (2014)
Spatial Localization of the Ebola Virus Glycoprotein Mucin-Like Domain Determined by Cryo-Electron Tomography Erin E. H. Tran, James A. Simmons, Alberto Bartesaghi, Charles J. Shoemaker, Elizabeth Nelson, Judith M. White and Sriram Subramaniam J. Virology, doi: 10.1128/JVI.00870-14 (2014)
Integrated Design of Antibodies for Systems Biology Using AbDesigner Trairak Pisitkun, Patrick Dummer, Poorichaya Somparn, Nattiya Hirankarn, Jeffrey B Kopp and Mark A Knepper Proteomics and Bioinformatics, doi://10.4172/jpb.1000307 (2014)
Parkinson's disease in GTP cyclohydrolase 1 mutation carriers Niccoló E. Mencacci, Ioannis U. Isaias, Martin M. Reich et al. Brain, doi: 10.1093/brain/awu179 (2014)

Brain Network Informed Subject Community Detection In Early-Onset Schizophrenia Zhi Yang, Yong Xu, Ting Xu, Colin W. Hoy, Daniel A. Handwerker, Gang Chen, Georg Northoff, Xi-Nian Zuo & Peter A. Bandettini Scientific Reports, doi:10.1038/srep05549 (2014)
Role of Albumin in the Formation and Stabilization of Nanoparticle Aggregates in Serum Studied by Continuous Photon Correlation Spectroscopy and Multiscale Computer Simulations Ashwinkumar A. Bhirde , Sergio A Hassan , Erick Harr , and Xiaoyuan Chen J. Phys. Chem. C, DOI: 10.1021/jp5034068 (2014)
Comparative validation of the D. melanogaster modENCODE transcriptome annotation ZX Chen, D Sturgill, J Qu, H Jiang et al. Genome Research, doi://10.1101/gr.159384.113 (2014)
Phosphoproteomic Analysis Reveals Regulatory Mechanisms at the Kidney Filtration Barrier Markus M. Rinschen, Xiongwu Wu, Tim K�nig, Trairak Pisitkun, Henning Hagmann, Caroline Pahmeyer, Tobias Lamkemeyer, Priyanka Kohli, Nicole Schnell, Bernhard Schermer, Stuart Dryer, Bernard R. Brooks, Pedro Beltrao, Marcus Krueger, Paul T. Brinkkoetter, Thomas Benzing J Am Soc Nephrol., doi: 10.1681/ASN.2013070760 (2014)
Common genetic variation in the glucokinase gene (GCK) is associated with type 2 diabetes and rates of carbohydrate oxidation and energy expenditure Muller YL, Piaggi P, Hoffman D, Huang K, Gene B, Kobes S, Thearle MS, Knowler WC, Hanson RL, Baier LJ, Bogardus C Diabetologia, doi: 10.1007/s00125-014-3234-8 (2014)
Task Dependence, Tissue Specificity, and Spatial Distribution of Widespread Activations in Large Single-Subject Functional MRI Datasets at 7T Javier Gonzalez-Castillo, Colin W. Hoy, Daniel A. Handwerker, Vinai Roopchansingh, Souheil J. Inati, Ziad S. Saad, Robert W. Cox and Peter A. Bandettini Cerebral Cortex, doi://10.1093/cercor/bhu148 (2014)

Corpus Callosum Size Is Highly Heritable in Humans, and May Reflect Distinct Genetic Influences on Ventral and Rostral Regions Girma Woldehawariat, Pedro E. Martinez, Peter Hauser, David M. Hoover, Wayne W. C. Drevets, Francis J. McMahon PLoS One, DOI: 10.1371/journal.pone.0099980 (2014)
Thermodynamic, Dynamic and Solvational Properties of PDEδ Binding to Farnesylated Cystein: A Model Study for Uncovering the Molecular Mechanism of PDEδ Interaction with Prenylated Proteins S. Suladze, S. Ismail, and R. Winter J. Phys. Chem. B, DOI: 10.1021/jp411466r (2014)
Inhibition of Paracoccidioides lutzii Pb01 Isocitrate Lyase by the Natural Compound Argentilactone and Its Semi-Synthetic Derivatives Renata Silva do Prado, Ricardo Justino Alves et al PLoS One, DOI: 10.1371/journal.pone.0094832 (2014)
Genome-wide association analysis identifies six new loci associated with forced vital capacity Loth DW, Artigas MS, Gharib SA et al. Nat Genet., doi: 10.1038/ng.3011. (2014)
Introductions and evolution of human-origin seasonal influenza A viruses in multinational swine populations Martha I. Nelson, David E. Wentworth, Marie R. Culhane, Amy L. Vincent, Cecile Viboud, Matthew P. LaPointe, Xudong Lin, Edward C. Holmes and Susan E. Detmer J. Virology, doi: 10.1128/JVI.01080-14 (2014)
The evolutionary dynamics of influenza A and B viruses in the tropical city of Managua, Nicaragua Martha I. Nelson, Angel Balmaseda, Guillermina Kuan, Saira Saborio, Xudong Lin, Rebecca A. Halpin, Timothy B. Stockwell, David E. Wentworth, Eva Harris, Aubree Gordon Virology, DOI: 10.1016/j.virol.2014.05.025 (2014)
Highly efficient production of peptides: N-glycosidase F for N-glycomics analysis Ling Hua, b, Xin Gao, Xiaopan Yang, Deyou Wan, Chunpeng He, Jiyue Cao, Haifeng Song Protein Expression and Purification, DOI: 10.1016/j.pep.2014.02.004 (2014)
Approaches to retrospective sampling for longitudinal transition regression models Sally Hunsberger, Paul S. Albert, and Marie Thoma Statistics and Its Interface 7:75-85, doi://10.4310/SII.2014.v7.n1.a9 (2014)
Identification and Characterization of Seminal Fluid Proteins in the Asian Tiger Mosquito, Aedes albopictus Kathryn E. Boes, José M. C. Ribeiro, Alex Wong, Laura C. Harrington, Mariana F. Wolfner, and Laura K. Sirot PLoS Neglected Tropical Diseases, doi: 10.1371/journal.pntd.0002946 (2014)
Marginal analysis of measurement agreement among multiple raters with non-ignorable missing ratings Zhen Chen and Yunlong Xie Statistics and Its Interface 7:113-120, doiL//10.4310/SII.2014.v7.n1.a12 (2014)
Linear mixed models for multiple outcomes using extended multivariate skew-t distributions Binbing Yu, A. James O'Malley, and Pulak Ghosh Statistics and Its Interface 7:101-111, doi://10.4310/SII.2014.v7.n1.a11 (2014)
Matched longitudinal analysis of biomarkers associated with survival Lori E. Dodd, Reed F. Johnson, Joseph E. Blaney and Dean Follmann Clinical & Vaccine Immunology, doi: 10.1128/CVI.00252-14 (2014)

Frontotemporal dementia and its subtypes: a genome-wide association study Ferrari R, Hernandez D, Nalls M et al. The Lancet Neurology, DOI: 10.1016/S1474-4422(14)70065-1 (2014)
Activity and Architecture of Pyroglutamate Modified Amyloid-β (AβpE3-42) Pores Alan L Gillman , Hyunbum Jang , Joon Lee , Srinivasan Ramachandran , Bruce L. Kagan , Ruth Nussinov , and Fernando Teran Arce J. Phys. Chem. B, DOI: 10.1021/jp5040954 (2014)
Computational Tools and Algorithms for Designing Customized Synthetic Genes Nathan Gould, Oliver Hendy, and Dimitris Papamichail Front Bioeng Biotechnol, doi: 10.3389/fbioe.2014.00041 (2014)
Role of LDB1 in the transition from chromatin looping to transcription activation. Krivega I, Dale RK, Dean A. Genes Dev., doi: 10.1101/gad.239749.114 (2014)
Implicit treatment of solvent dispersion forces in protein simulations Sergio A Hassan Journal of Computational Chemistry, DOI: 10.1002/jcc.23655 (2014)
Conscious recall of different aspects of skill memory Sunbin Song & Leonardo G Cohen Frontiers in Behavioural Neuroscience, doi:10.3389/fnbeh.2014.00233 (2014)

A novel role of CDX1 in embryonic epicardial development Chu M, Wang L, Wang H, Shen T, Yang Y, Sun Y, Tang N, Ni T, Zhu J, Mailman RB, Wang Y PLoS One, doi: 10.1371/journal.pone.0103271 (2014)
Pre-fusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy Alberto Bartesaghi, Alan Merk, Mario J. Borgnia, Jacqueline L. S. Milne, and Sriram Subramaniam Nat Struct Mol Biol., doi: 10.1038/nsmb.2711 (2014)
The spatial structure of resting state connectivity stability on the scale of minutes Javier Gonzalez-Castillo, Daniel A Handwerker, Meghan E. Robinson, Colin Wier Hoy, Laura Cathleen Buchanan, Ziad S Saad and Peter A Bandettini Frontiers in Neuroscience, DOI://10.3389/fnins.2014.00138 (2014)
The RNA-binding protein Rumpelstiltskin antagonizes gypsy chromatin insulator function in a tissue-specific manner. King MR, Matzat LH, Dale RK, Lim SJ, Lei EP J. Cell. Sci., doi: 10.1242/jcs.151126 (2014)
Use of LC-MS/MS and Bayes' Theorem to Identify Protein Kinases That Phosphorylate Aquaporin-2 at Ser256 Davis Bradford, Viswanathan Raghuram, Justin L.L. Wilson, Chung-Lin Chou, Jason D. Hoffert, Mark A. Knepper, Trairak Pisitkun Am. J. Physiol. - Cell Physiol. , DOI: 10.1152/ajpcell.00377.2012 (2014)
Nill-Schiff base complex as an enzyme inhibitor of hen egg white lysozyme: a crystallographic and spectroscopic study Banabithi Koley Seth, Aurkie Ray, Sampa Biswas and Samita Basu Metallomics, DOI: 10.1039/C4MT00098F (2014)

Identification of the Genomic Insertion Site of Pmel-1 TCR α and β Transgenes by Next-Generation Sequencing Yun Ji, Natalie Abrams, Wei Zhu, Eddie Salinas, Zhiya Yu, Douglas C. Palmer, Parthav Jailwala, Zulmarie Franco, Rahul Roychoudhuri, Eric Stahlberg, Luca Gattinoni, Nicholas P. Restifo PLoS One, DOI: 10.1371/journal.pone.0096650 (2014)
Combination of longitudinal biomarkers in predicting binary events Danping Liu and Paul S Albert Biostatistics, doi: 10.1093/biostatistics/kxu020 (2014)
Rare missense variants in POT1 predispose to familial cutaneous malignant melanoma Shi J, Yang XR, Ballew B Nature Genetics, doi: 10.1038/ng.2941 (2014)
Pleiotropic genes for metabolic syndrome and inflammation Kraja AT, Chasman DI, North KE et al. Molecular Genetics & Metabolism, doi://10.1016/j.ymgme.2014.04.007 (2014)
Perturbation of nuclear spin polarizations in solid state NMR of nitroxide-doped samples by magic-angle spinning without microwaves Kent R. Thurber and Robert Tycko J. Chem. Phys. , DOI: 10.1063/1.4874341 (2014)
Rhythmic Bursting in the Pre-Bötzinger Complex: Mechanisms and Models Ilya A. Rybak, Yaroslav I. Molkov, Patrick E. Jasinski, Natalia A. Shevtsova, Jeffrey C. Smith Progress in Brain Research, doi://10.1016/B978-0-444-63274-6.00001-1 (2014)

Early targets of lithium in rat kidney inner medullary collecting duct include p38 and ERK1/2 Francesco Trepiccione, Trairak Pisitkun, Jason D Hoffert, Søren B Poulsen, Giovambattista Capasso, Søren Nielsen, Mark A Knepper, Robert A Fenton and Birgitte M Christensen Kidney International, doi: 10.1038/ki.2014.107 (2014)
Electrostatics, hydration, and proton transfer dynamics in the membrane domain of respiratory complex I Ville R. I. Kaila, Mârten Wikström and Gerhard Hummer PNAS, doi: 10.1073/pnas.1319156111 (2014)
Hierarchical clustering of ryanodine receptors enables emergence of a calcium clock in sinoatrial node cells Michael D. Stern, Larissa A. Maltseva, Magdalena Juhaszova, Steven J. Sollott, Edward G. Lakatta, and Victor A. Maltsev J. Gen. Physiol. , doi: 10.1085/jgp.201311123 (2014)
Progress in the search for histidine acid phosphatase inhibitors in Francisella tularensis Ruoyi Pu DS Thesis, U. Texas (2014)
Conserved hydrogen-bonding network of P2 bis-tetrahydrofuran containing HIV-1 protease inhibitors (PI) with protease active site amino acid-backbone aid in their activity against PI-resistant HIV Ravikiran S. Yedidi, Harisha Garimella, Manabu Aoki, Hiromi Aoki, Darshan V. Desai, Simon B. Chang, David A. Davis, W. Sean Fyvie, Joshua D. Kaufman, David W. Smith, Debananda Das, Paul T. Wingfield, Kenji Maeda, Arun K. Ghosh and Hiroaki Mitsuya Antimicrob Agents Chemother., doi://10.1128/AAC.00107-14 (2014)
Non-invasive urinary metabolomic profiling identifies diagnostic and prognostic markers in lung cancer Ewy A Mathe, Andrew D Patterson, Majda Haznadar, Soumen K Manna, Kristopher W. Krausz, Elise D Bowman, Peter G. Shields, Jeffrey R. Idle, Philip B Smith, Katsuhiro Anami, Dickran Kazandjian, Emmanuel Hatzakis, Frank J Gonzalez, and Curtis C. Harris Cancer Res., doi:10.1158/0008-5472.CAN-14-0109 (2014)

Impact of subdomain D1 of the short form S1b of the human prolactin receptor on its inhibitory action on the function of the long form of the receptor induced by prolactin J.-H. Kang, S.A. Hassan, 1, P. Zhao, C.H. Tsai-Morris, M.L. Dufau Biochim. et Biophys. Acta, doi://10.1016/j.bbagen.2014.04.006 (2014)
A Fast and Powerful Tree-Based Association Test for Detecting Complex Joint Effects in Case-Control Studies Han Zhang, William Wheeler, Zhaoming Wang, Philip R. Taylor and Kai Yu Bioinformatics, doi://10.1093/bioinformatics/btu186 (2014)
Post-Translational Decrease in Respiratory Chain Proteins in the Polg Mutator Mouse Brain David N. Hauser, Allissa A. Dillman, Jinhui Ding, Yan Li, Mark R. Cookson PLoS One, DOI: 10.1371/journal.pone.0094646 (2014)
Studies on Inhibition of Respiratory Cytochrome bc1 Complex by the Fungicide Pyrimorph Suggest a Novel Inhibitory Mechanism Yu-Mei Xiao, Lothar Esser, Fei Zhou, Chang Li, Yi-Hui Zhou, Chang-An Yu, Zhao-Hai Qin, Di Xia PLoS One, DOI: 10.1371/journal.pone.0093765 (2014)
Regulation of a novel isoform of Receptor Expression Enhancing Protein REEP6 in rod photoreceptors by bZIP transcription factor NRL Hong Hao, Shobi Veleri, Bo Sun, Douglas S. Kim, Patrick W. Keeley, Jung-Woong Kim, Hyun-Jin Yang, Sharda P. Yadav, Souparnika H. Manjunath, Raman Sood, Paul Liu, Benjamin E. Reese and Anand Swaroop Human Molecular Genetics, doi: 10.1093/hmg/ddu143 (2014)
Distributed MRI reconstruction using gadgetron-based cloud computing Hui Xue, Souheil Inati, Thomas Sangild Sørensen, Peter Kellman and Michael S. Hansen Magnetic Resonance in Medicine, DOI: 10.1002/mrm.25213 (2014)

Hemoglobinopathic erythrocytes affect the intraerythrocytic multiplication of Plasmodium falciparum in vitro Svetlana Glushakova, Amanda Balaban, Philip G. McQueen, Rosane Coutinho, Jeffery L. Miller, Ralph Nossal, Rick M. Fairhurst, Joshua Zimmerberg J. Infectious Diseases, doi:10.1093/infdis/jiu203 (2014)
A potent anti-dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface Guntur Fibriansah, Joanne L Tan,Scott A Smith, Adamberage R Alwis, Thiam-Seng Ng, Victor A Kostyuchenko, Kristie D Ibarra, Jiaqi Wang, Eva Harris, Aravinda Silva, James E Crowe, and Shee-Mei Lok EMBO Molecular Medicine, doi: 10.1002/emmm.201303404 (2014)
A mixture of transition models for heterogeneous longitudinal ordinal data: with applications to longitudinal bacterial vaginosis data Kyeongmi Cheon, Marie E. Thoma, Xiangrong Kong and Paul S. Albert Statistics in Medicine, DOI: 10.1002/sim.6151 (2014)
Abdominal lymphadenopathy detection using random forest Kevin M. Cherry, Shijun Wang, Evrim B. Turkbey, Ronald M. Summers SPIE Proceedings, Volume 9035, Lung, Chest, and Abdomen II, doi:10.1117/12.2043837 (2014)
VTET: a variable threshold exact test for identifying disease-associated copy number variations enriched in short genomic regions Jianxin Shi, Xiaohong R. Yang, Neil E. Caporaso, Maria T. Landi, and Peng Li Frontiers in Genetics, doi://10.3389/fgene.2014.00053 (2014)
Accuracy Evaluation of the Unified P-Value from Combining Correlated P-Values Gelio Alves and Yi-Kuo Yu PLoS One, doi: 10.1371/journal.pone.0091225 (2014)

Differential Coding of Conspecific Vocalizations in the Ventral Auditory Cortical Stream Makoto Fukushima, Richard C. Saunders, David A. Leopold, Mortimer Mishkin, and Bruno B. Averbeck J. Neuroscience, doi: 10.1523/JNEUROSCI.3969-13.2014 (2014)
Contradictions in X-ray structures of intermediates in the photocycle of photoactive yellow protein Ville R. I. Kaila, Friedrich Schotte, Hyun Sun Cho, Gerhard Hummer & Philip A. Anfinrud Nature Chemistry, doi:10.1038/nchem.1898 (2014)
Practice and sleep form different aspects of skill Sunbin Song & Leonardo G. Cohen Nature Communications, doi:10.1038/ncomms4407 (2014)
Temperature-dependent solvation modulates the dimensions of disordered proteins René Wuttke, Hagen Hofmann, Daniel Nettels, Madeleine B. Borgia, Jeetain Mittal, Robert B. Best, and Benjamin Schuler PNAS, doi: 10.1073/pnas.1313006111 (2014)
Hypoosmotic Expression of Dunaliella bardawil ζ-Carotene Desaturase Is Attributed to a Hypoosmolarity-Responsive Element Different from Other Key Carotenogenic Genes Yong-Min Lao, Lan Xiao, Li-Xin Luo and Jian-Guo Jiang Plant Physiology, doi://10.1104/pp.114.235390 (2014)
Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue Jianxin Shi, Crystal N. Marconett, Jubao Duan et al. Nature Communications, doi:10.1038/ncomms4365 (2014)

Disordered amyloidogenic peptides may insert into the membrane and assemble into common cyclic structural motifs Hyunbum Jang, Fernando Teran Arce, Srinivasan Ramachandran, Bruce L. Kagan, Ratnesh Lal and Ruth Nussinov Chem. Soc. Rev., doi://10.1039/C3CS60459D (2014)
Abnormal cortical growth in schizophrenia targets normative modules of synchronized development Aaron F. Alexander-Bloch, Philip T. Reiss, Judith Rapoport, Harry McAdams, Jay N. Giedd, Ed T. Bullmore, Nitin Gogtay Biological Psychiatry, doi://10.1016/j.biopsych.2014.02.010 (2014)
Calcium Inhibition of Ribonuclease H1 Two-Metal Ion Catalysis Edina Rosta, Wei Yang, and Gerhard Hummer JACS, DOI: 10.1021/ja411408x (2014)
Multiscale free energy simulations: An efficient method for connecting classical MD simulations to QM or QM/MM free energies using Non-Boltzmann Bennett reweighting schemes Gerhard König, Phillip Stephen Hudson, Stefan Boresch, and H. Lee Woodcock J. Chem. Theory & Computation, DOI: 10.1021/ct401118k (2014)
A Network Characteristic That Correlates Environmental and Genetic Robustness Zeina Shreif, Vipul Periwal PLoS Computational Biology, DOI: 10.1371/journal.pcbi.1003474 (2014)
A GCH1 haplotype confers sex-specific susceptibility to pain crises and altered endothelial function in adults with sickle cell anemia Inna Belfer, Victoria Youngblood et al. Am. J. Hematology, DOI: 10.1002/ajh.23613 (2014)

Meta-analysis of Loci Associated with Age at Natural Menopause in African-American Women CTL Chen, C-T Liu, GK Chen, et al Human Molecular Genetics, doi: 10.1093/hmg/ddu041 (2014)
Predicting hydration free energies with a hybrid QM/MM approach: an evaluation of implicit and explicit solvation models in SAMPL4 Gerhard König, Frank C. Pickard IV, Ye Mei, Bernard R. Brooks J. Computer-Aided Molecular Design, doi://10.1007/s10822-014-9708-4 (2014)
Predicting Stroke Through Genetic Risk Functions CA Ibrahim-Verbaas,M Fornage, JC Bis, et al Stroke, doi: 10.1161/STROKEAHA.113.003044 (2014)
Multilocus Genetic Risk Score Associates With Ischemic Stroke in Case-Control and Prospective Cohort Studies R Malik, S Bevan, M Nalls et al Stroke, doi: 10.1161/STROKEAHA.113.002938 (2014)
Reverse regression: A method for joint analysis of multiple endpoints in randomized clinical trials Zhiwei Zhang Statistica Sinica, doi://10.5705/ss.2010.111 (2014)
Using single cell sequencing data to model the evolutionary history of a tumor Kyung In Kim and Richard Simon BMC Bioinformatics :27, doi: 10.1186/1471-2105-15-27 (2014)

Comprehensive Genomic Analysis of Rhabdomyosarcoma Reveals a Landscape of Alterations Affecting a Common Genetic Axis in Fusion-Positive and Fusion-Negative Tumors Jack F. Shern, Li Chen, Juliann Chmielecki, et al. Cancer Discovery, doi:10.1158/2159-8290.CD-13-0639 (2014)
Fluorescence excitation and ultraviolet absorption spectra and theoretical calculations for benzocyclobutane: Vibrations and structure of its excited S1(π,π*) electronic state Hee Won Shin, Esther J. Ocola, Sunghwan Kim and Jaan Laane J. Chem. Phys., doi://10.1063/1.4858412 (2014)
Spectral Tuning of Rhodopsin and Visual Cone Pigments Xiuwen Zhou , Dage Sundholm , Tomasz Adam Wesolowski , and Ville R. I. Kaila J.Am.Chem.Soc., DOI: 10.1021/ja411864m (2014)
RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder N Akula, J Barb, X Jiang, J R Wendland, K H Choi, S K Sen, L Hou, D T W Chen, G Laje, K Johnson, B K Lipska, J E Kleinman, H Corrada-Bravo, S Detera-Wadleigh, P J Munson and F J McMahon Molecular Psychiatry, doi: 10.1038/mp.2013.170 (2014)

2013 (141 papers)

PhosSA: Fast and accurate phosphorylation site assignment algorithm for mass spectrometry data Fahad Saeed, Trairak Pisitkun, Jason D Hoffert, Sara Rashidian, Guanghui Wang, Marjan Gucek and Mark A Knepper Proteome Sci. , doi: 10.1186/1477-5956-11-S1-S14 (2013)
Molecular insights into the reversible formation of tau protein fibrils Yin Luo, Paul Dinkel, Xiang Yu, Martin Margittai, Jie Zheng, Ruth Nussinov, Guanghong Wei and Buyong Ma Chem. Commun., DOI: 10.1039/C3CC00241A (2013)
Developing a library of recognition proteins using FimH as a protein scaffold Rochelle Nguyen Master's Thesis, U. Washington (2013)
Interactome Maps of Mouse Gene Regulatory Domains Reveal Basic Principles of Transcriptional Regulation Kyong-Rim Kieffer-Kwon, Zhonghui Tang, Ewy Mathe et al. Cell, doi://10.1016/j.cell.2013.11.039 (2013)
Design of RNA splicing analysis null models for post hoc filtering of Drosophila head RNA-Seq data with the splicing analysis kit (Spanki) David Sturgill, John H Malone, Xia Sun, Harold E Smith, Leonard Rabinow, Marie-Laure Samson and Brian Oliver BMC Bioinformatics, doi:10.1186/1471-2105-14-320 (2013)
Theta band activity in response to emotional expressions and its relationship with gamma band activity as revealed by MEG and advanced beamformer source imaging Qian Luo, Xi Cheng, Tom Holroyd, Duo Xu, Frederick W. Carver and James Blair Frontiers in Human Neuroscience, doi: 10.3389/fnhum.2013.00940 (2013)
Overfitting, generalization, and MSE in class probability estimation with high-dimensional data Kyung In Kim, Richard Simon Biometric Journal, DOI: 10.1002/bimj.201300083 (2013)
Radionuclide labeling and evaluation of candidate radioligands for PET imaging of histone deacetylase in the brain Young Jun Seo, Lisa Muench, Alicia Reid, Jinzhu Chen, Yeona Kang, Jacob M. Hooker, Nora D. Volkow, Joanna S. Fowler, Sung Won Kim Bioorganic and Medicinal Chemistry Letters 23:6700-6705 (2013)

An integrated systems genetics screen reveals the transcriptional structure of inherited predisposition to metastatic disease Farhoud Faraji, Ying Hu, Gang Wu, Natalie E. Goldberger, Renard C. Walker, Jinghui Zhang and Kent W. Hunter Genome Research, doi: 10.1101/gr.166223.113 (2013)
Efficacy of Cyclin Dependent Kinase 4 Inhibitors as Potent Neuroprotective Agents against Insults Relevant to Alzheimer's Disease Priyankar Sanphui, Sumit Kumar Pramanik, Nandini Chatterjee, Ponnusamy Moorthi, Biswadip Banerji, Subhas Chandra Biswas PLoS One, doi: 10.1371/journal.pone.0078842 (2013)
Multiple Transport-Active Binding Sites Are Available for a Single Substrate on Human P-Glycoprotein (ABCB1) Eduardo E. Chufan, Khyati Kapoor, Hong-May Sim, Satyakam Singh, Tanaji T. Talele, Stewart R. Durell, Suresh V. Ambudkar PLoS One, DOI: 10.1371/journal.pone.0082463 (2013)
Prediction of the location and size of the stomach using patient characteristics for retrospective radiation dose estimation following radiotherapy Stephanie Lamart, Rebecca Imran, Steven L Simon, Kazutaka Doi, Lindsay M Morton, Rochelle E Curtis, Choonik Lee, Vladimir Drozdovitch, Roberto Maass-Moreno, Clara C Chen, Millie Whatley, Donald L Miller, Karel Pacak and Choonsik Lee Physics in Medicine and Biology, doi:10.1088/0031-9155/58/24/8739 (2013)
Optimization of virus detection in cells using massively parallel sequencing Shasta D. McClenahan, Christine Uhlenhaut, Philip R. Krause Biologicals, DOI://10.1016/j.biologicals.2013.11.002 (2013)
Whole exome sequencing identifies variation in CYB5A and RNF10 associated with adiposity and type 2 diabetes. Huang K, Nair AK, Muller YL, Piaggi P, Bian L, Del Rosario M, Knowler WC, Kobes S, Hanson RL, Bogardus C, Baier LJ. Obesity, doi: 10.1002/oby.20647 (2013)
Antimicrobial activity of eugenol and cinnamaldehyde against extended spectrum beta lactamase producing enterobacteriaceae by in vitro and molecular docking analysis Lena Dhara, Anusri Tripathi Eur.J.Integrative Med., 10.1016/j.eujim.2013.08.005 (2013)
Efficient logistic regression designs under an imperfect population identifier Paul S. Albert, Aiyi Liu, Tonja Nansel Biometrics, DOI: 10.1111/biom.12106 (2013)
Molecular Isotopic Distribution Analysis (MIDAs) with Adjustable Mass Accuracy Gelio Alves, Aleksey Y. Ogurtsov, Yi-Kuo Yu J. Am. Soc. for Mass Spectrometry, doi://10.1007/s13361-013-0733-7 (2013)
Vitamin D-Binding Protein and Vitamin D Status of Black Americans and White Americans Camille E. Powe, , Michele K. Evans, Julia Wenger, Alan B. Zonderman, Anders H. Berg, Michael Nalls, Hector Tamez, Dongsheng Zhang, Ishir Bhan, S. Ananth Karumanchi, Neil R. Powe, and Ravi Thadhani New England J. Medicine, DOI: 10.1056/NEJMoa1306357 (2013)
PW02-001 - Exome sequencing for autoinflammatory disorders SE Boyden, Q Zhou, I Aksentijevich and DL Kastner Pediatric Rheumatology, doi:10.1186/1546-0096-11-S1-A141 (2013)
Endogenous Carbamylation of Renal Medullary Proteins J'Neka S. Claxton, Pablo C. Sandoval, Gary Liu, Chung-Lin Chou, Jason D. Hoffert, and Mark A. Knepper PLoS One, doi: 10.1371/journal.pone.0082655 (2013)

Interpreting the effects of altered brain anatomical connectivity on fMRI functional connectivity: a role for computational neural modeling Barry Horwitz, Chuhern Hwang, and Jeff Alstott Frontiers in Human Neuroscience, doi: 10.3389/fnhum.2013.00649 (2013)
Shared Genetic Susceptibility to Ischemic Stroke and Coronary Artery Disease Dichgans, Malik et al. Stroke, doi: 10.1161/STROKEAHA.113.002707 (2013)
Mtr4-like Protein Coordinates Nuclear RNA Processing for Heterochromatin Assembly and for Telomere Maintenance Nathan N. Lee, Venkata R. Chalamcharla, Francisca Reyes-Turcu, Sameet Mehta, Martin Zofall, Vanivilasini Balachandran, Jothy Dhakshnamoorthy, Nitika Taneja, Soichiro Yamanaka, 5, Ming Zhou, Shiv I.S. Grewal Cell, doi://10.1016/j.cell.2013.10.027 (2013)
Testing multiple biological mediators simultaneously Simina M. Boca, Rashmi Sinha, Amanda J. Cross, Steven C. Moore and Joshua N. Sampson Bioinformatics, doi: 10.1093/bioinformatics/btt633 (2013)
Variational Optimization of an All-Atom Implicit Solvent Force Field To Match Explicit Solvent Simulation Data Sandro Bottaro, Kresten Lindorff-Larsen, and Robert B. Best J. Chem. Theory and Computation, DOI: 10.1021/ct400730n (2013)
Mechanism of Membrane Permeation Induced by Synthetic β-Hairpin Peptides Kshitij Gupta, Hyunbum Jang, Kevin Harlen, Anu Puri, Ruth Nussinov, Joel P. Schneider, Robert Blumenthal Biophys. J. , doi: 10.1016/j.bpj.2013.09.040 (2013)

Ebola Virus RNA Editing Depends on the Primary Editing Site Sequence and an Upstream Secondary Structure Masfique Mehedi, Thomas Hoenen, Shelly Robertson, Stacy Ricklefs, Michael A. Dolan, Travis Taylor, Darryl Falzarano, Hideki Ebihara, Stephen F. Porcella, Heinz Feldmann PLoS Pathogens, doi:10.1371/journal.ppat.1003677 (2013)
Massively Parallel Sequencing Reveals an Accumulation of De Novo Mutations and an Activating Mutation of LPAR1 in a Patient with Metastatic Neuroblastoma JS Wei, P Johansson, L Chen et al PLoS One, doi:10.1371/journal.pone.0077731 (2013)
Mitochondrial DNA sequence associations with dementia and amyloid-β in elderly African Americans GJ Tranah, JS Yokoyoma, SM Katzman et al. Neurobiology of Aging, doi:/10.1016/j.neurobiolaging.2013.05.02 (2013)
Functional Linear Models for Association Analysis of Quantitative Traits Ruzong Fan, Yifan Wang, James L. Mills, Alexander F. Wilson, Joan E. Bailey-Wilson, Momiao Xiong Genetic Epidemiology, DOI: 10.1002/gepi.21757 (2013)
Singular Value Decomposition of the Radial Distribution Function for Hard Sphere and Square Well Potentials Travis Hoppe PLoS One, doi:10.1371/journal.pone.0075792 (2013)
Brain Docosahexaenoic Acid [DHA] Incorporation and Blood Flow Are Increased in Chronic Alcoholics: A Positron Emission Tomography Study Corrected for Cerebral Atrophy J.C. Umhau, W. Zhou, S. Thada et al PLoS One, doi:10.1371/journal.pone.0075333 (2013)

Cyclic N-Terminal Loop of Amylin Forms Non Amyloid Fibers Stephanie M. Cope, Sandip Shinde, Robert B. Best, Giovanna Ghirlanda, Sara M. Vaiana Biophys. J. , doi: 10.1016/j.bpj.2013.08.026 (2013)
Infrared, Raman, and Ultraviolet Absorption Spectra and Theoretical Calculations and Structure of 2, 6-Difluoropyridine in its Ground and Excited Electronic States Hong-Li Sheu, Sunghwan Kim, and Jaan Laane J. Phys. Chem. A, DOI://10.1021/jp407592r (2013)
Assessment of Parkinson's disease risk loci in Greece E. Kara, G. Xiromerisiou, C. Spanaki et al Neurobiology of Aging, doi://10.1016/j.neurobiolaging.2013.07.011 (2013)
Sequential Monte Carlo Tracking for Marginal Artery Segmentation on CT Angiography by Multiple Cue Fusion Shijun Wang, Brandon Peplinski, Le Lu, Weidong Zhang, Jianfei Liu, Zhuoshi Wei, Ronald M. Summers Medical Image Computing and Computer-Assisted Intervention 8150:518-525 (2013)
Strategies for developing prediction models from genome-wide association studies. Jincao Wu, Ruth M. Pfeiffer andMitchell H. Gail Genet Epidemiol. , doi: 10.1002/gepi.21762 (2013)
Phosphate release coupled to rotary motion of F1-ATPase Kei-ichi Okazaki and Gerhard Hummer PNAS, doi: 10.1073/pnas.1305497110 (2013)
Genome-wide analysis of blood pressure variability and ischemic stroke Yadav, S; Cotlarciuc, I; Munroe, PB et al. Stroke, DOI://10.1161/STROKEAHA.113.002186 (2013)
Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation Gangqing Hu, Qingsong Tang, Suveena Sharma, Fang Yu, Thelma M Escobar, Stefan A Muljo, Jinfang Zhu & Keji Zhao Nature Immunology, doi:10.1038/ni.2712 (2013)
Specific and Non-Specific Protein Association in Solution: Computation of Solvent Effects and Prediction of First-Encounter Modes for Efficient Configurational Bias Monte Carlo Simulations Antonio Cardone , Harish C. Pant , and Sergio A Hassan J. Phys. Chem. B, DOI: 10.1021/jp4050594 (2013)
Molecular Structure of β-Amyloid Fibrils in Alzheimer's Disease Brain Tissue Jun-Xia Lu, Wei Qiang, Wai-Ming Yau, Charles D. Schwieters, Stephen C. Meredith, Robert Tycko Cell, doi: 10.1016/j.cell.2013.08.035 (2013)
A fast multilocus test with adaptive SNP selection for large-scale genetic-association studies Han Zhang, Jianxin Shi, Faming Liang, William Wheeler, Rachael Stolzenberg-Solomon and Kai Yu Eur. J. Human Genetics, doi: 10.1038/ejhg.2013.201 (2013)
Sequence selectivity of the cleavage sites induced by topoisomerase I inhibitors: a molecular dynamics study Fung-Ming Siu and Yves Pommier Nucleic Acids Research, doi://10.1093/nar/gkt791 (2013)
Gene Synthesis Method Based on Overlap Extension PCR and DNAWorks Program Gang Li, Bing-Xue Dong, Yu-Huan Liu, Chang-Jie Li, Li-Ping Zhang Synthetic Biology - Methods in Molecular Biology 1073:9-17 (2013)
Proteomic profiling of the rat renal proximal convoluted tubule in response to chronic metabolic acidosis Dana Marie Freund Ph.D. Thesis, Colorado State University (2013)
Effect of acute acid-base disturbances on ErbB1/2 tyrosine phosphorylation in rabbit renal proximal tubules Lara A. Skelton, Walter F. Boron Am. J. Physiol. - Renal Physiol., DOI: 10.1152/ajprenal.00307.2013 (2013)
Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases for genome engineering applications Sarah Baxter Ph.D thesis, U. Washington (2013)
Genetic comorbidities in Parkinson's disease MA Nalls,M Saad et al. Human Molecular Genetics, doi: 10.1093/hmg/ddt465 (2013)
Familial Alzheimer's Disease Osaka Mutant (ΔE22) β-Barrels Suggest an Explanation for the Different Aβ1-40/42 Preferred Conformational States Observed by Experiment Hyunbum Jang , Fernando Teran Arce , Srinivasan Ramachandran , Bruce L. Kagan , Ratnesh Lal , and Ruth Nussinov J. Phys. Chem. B, DOI: 10.1021/jp405389n (2013)

Life and death of a cardiac calcium spark Michael D. Stern, Eduardo Ríos, and Victor A. Maltsev J. Gen. Physiol. , doi: 10.1085/jgp.201311034 (2013)
Conformational Analysis of NMDA Receptor GluN1, GluN2, and GluN3 Ligand-Binding Domains Reveals Subtype-Specific Characteristics Yongneng Yao, John Belcher, Anthony J. Berger, Mark L. Mayer, Albert Y. Lau Structure, doi: 10.1016/j.str.2013.07.011 (2013)
Correlated vibrations in ion-pair dynamics in mechanoactivation identify functional domains of force-dependent titin kinase Ming-Chya Wu, Jeffrey G. Forbes and Kuan Wang Soft Matter, DOI: 10.1039/C3SM51539G (2013)
Genome-Wide Association of Body Fat Distribution in African Ancestry Populations Suggests New Loci Ching-Ti Liu, Keri L. Monda, Kira C. Taylor et al PLoS Genetics, doi:10.1371/journal.pgen.1003681 (2013)
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition Alika K Maunakea, Iouri Chepelev, Kairong Cui and Keji Zhao Cell Research, doi: 10.1038/cr.2013.110 (2013)
RCircos: an R package for Circos 2D track plots Hongen Zhang, Paul Meltzer, Sean Davis BMC Bioinformatics, doi:10.1186/1471-2105-14-244 (2013)

Top3 β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation Xu D, Shen W, Guo R, Xue Y, Peng W, Sima J, Yang J, Sharov A, Srikantan S, Yang J, Fox D 3rd, Qian Y, Martindale JL, Piao Y, Machamer J, Joshi SR, Mohanty S, Shaw AC, Lloyd TE, Brown GW, Ko MS, Gorospe M, Zou S, Wang W. Nature Neuroscience, doi: 10.1038/nn.3479 (2013)
Computational detection of abundant long-range nucleotide covariation in Drosophila genomes Eckart Bindewald and Bruce A Shapiro RNA, doi: 10.1261/rna.037630.112 (2013)
Multi-SNP Analysis of GWAS Data Identifies Pathways Associated with Nonalcoholic Fatty Liver Disease Qing-Rong Chen, Rosemary Braun, Ying Hu, Chunhua Yan, Elizabeth M. Brunt, Daoud Meerzaman, Arun J. Sanyal, Kenneth Buetow PLoS One, doi:10.1371/journal.pone.0065982 (2013)
Genomic Analysis of Stress Response against Arsenic in Caenorhabditis elegans Surasri N. Sahu, Jada Lewis, Isha Patel, Serdar Bozdag, Jeong H. Lee, Robert Sprando, and Hediye Nese Cinar PLoS One, doi://10.1371/journal.pone.0066431 (2013)
Genome-wide meta-analysis identifies new susceptibility loci for migraine Anttila, V; Winsvold, BS; Gormley, P et al. Nat. Genet., DOI://10.1038/ng.2676 (2013)
Reduced thalamic volumes in major depressive disorder AC Nugent, RM Davis, CA Zarate Jr, WC Drevets Psych. Res. Neuroimaging, doi://10.1016/j.pscychresns.2013.05.004 (2013)

Graph theoretical analysis of resting magnetoencephalographic functional connectivity networks Lindsay Rutter, Sreenivasan R. Nadar, Tom Holroyd, Frederick W. Carver, Jose Apud, Daniel R. Weinberger and Richard Coppola Frontiers in Computational Neuroscience, doi://10.3389/fncom.2013.00093 (2013)
Evaluation of the Use of Surrogate Tissues for Calculating Radiation Dose to Lymphatic Nodes from External Photon Beams Stephanie Lamart, Brian E. Moroz and Choonsik Lee Radiation Protection Dosimetry, doi: 10.1152/ajprenal.00210.2013 (2013)
Visual Phrase Learning and Its Application in Computed Tomographic Colonography Shijun Wang, Matthew McKenna, Zhuoshi Wei, Jiamin Liu, Peter Liu, Ronald M. Summers Medical Image Computing and Computer-Assisted Intervention 8149:243 (2013)
Ordinal latent variable models and their application in the study of newly licensed teenage drivers John C Jackson, Paul S. Albert, Zhiwei Zhang and Bruce Simons-Morton Appl. Statist. , DOI: 10.1111/j.1467-9876.2012.01065.x (2013)
Striatal dopamine release and genetic variation of the serotonin 2C receptor in humans Brian J Mickey, Benjamin J Sanford, Tiffany M Love, Pei-Hong Shen, Colin Hodgkinson, Christian S Stohler, David Goldman, Jon-Kar Zubieta J Neurosci., doi: 10.1523/JNEUROSCI.1260-12.2012 (2013)
DRD2/ANKK1 Taq1A polymorphism (rs1800497) has opposing effects on D2/3 receptor binding in healthy controls and patients with major depressive disorder Savitz J, Hodgkinson CA, Martin-Soelch C, Shen PH, Szczepanik J, Nugent AC, Herscovitch P, Grace AA, Goldman D, Drevets WC Int J Neuropsychopharmacol., doi: 10.1017/S146114571300045X (2013)

DockoMatic 2.0: High Throughput Inverse Virtual Screening and Homology Modeling Casey Bullock , Nic Cornia , Reed Jacob , Andrew Remm , Thomas Peavey , Ken Weekes , Chris Mallory , Julia Thom Oxford , Owen M. McDougal , and Timothy Lyon Andersen J. Chem. Inf. and Modeling, DOI: 10.1021/ci400047w (2013)
Contribution of nucleosome binding preferences and co-occurring DNA sequences to transcription factor binding X He, R Chatterjee, S John, H Bravo, Bk Sathyanarayana, SC Biddie, PC FitzGerald, JA Stamatoyannopoulos, GL Hager, C Vinson BMC Genomics, doi:10.1186/1471-2164-14-428 (2013)
Probing the transient dark state of substrate binding to GroEL by relaxation-based solution NMR David S. Libich, Nicolas L. Fawzia, Jinfa Ying, and G. Marius Clore PNAS, doi: 10.1073/pnas.1305715110 (2013)
HASP server: a database and structural visualization platform for comparative models of influenza A hemagglutinin proteins Xavier I Ambroggio, Jennifer Dommer, Vivek Gopalan, Eleca J Dunham, Jeffery K Taubenberger and Darrell E Hurt BMC Bioinformatics, doi:10.1186/1471-2105-14-197 (2013)
Host immune constraints on malaria transmission: insights from population biology of within-host parasites Philip G McQueen, Kim C Williamson and F Ellis McKenzie Malaria Journal, doi:10.1186/1475-2875-12-206 (2013)
VLDP web server: a powerful geometric tool for analysing protein structures in their environment Jérémy Esque, Sylvain Léonard, Alexandre G. de Brevern and Christophe Oguey Nucleic Acids Research, doi: 10.1093/nar/gkt509 (2013)

mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex. Dillman AA, Hauser DN, Gibbs JR, Nalls MA, McCoy MK, Rudenko IN, Galter D, Cookson MR. Nature Neuroscience, doi: 10.1038/nn.3332 (2013)
Proteome-Wide Measurement of Protein Half-Lives and Translation Rates in Vasopressin-Sensitive Collecting Duct Cells Pablo C. Sandoval, Dane H. Slentz, Trairak Pisitkun, Fahad Saeed, Jason D. Hoffert and Mark A. Knepper J. Am. Soc. Nephrologu, doi: 10.1681/ASN.2013030279 (2013)
Anatomical coupling among distributed cortical regions in youth varies as a function of individual differences in vocabulary abilities Nancy Raitano Lee, Armin Raznahan, Gregory L. Wallace, Aaron Alexander-Bloch, Liv S. Clasen, Jason P. Lerch, Jay N. Giedd Human Brain Mapping, DOI://10.1002/hbm.22299 (2013)
Serum Iron Levels and the Risk of Parkinson Disease: A Mendelian Randomization Study I Pichler, F Del Greco et al. PLoS Medicine, doi:10.1371/journal.pmed.1001462 (2013)
HIV-1 Envelope Glycoprotein Trimers Display Open Quaternary Conformation When Bound to the gp41 Membrane-Proximal External-Region-Directed Broadly Neutralizing Antibody Z13e1 Audray K. Harris, Alberto Bartesaghi, Jacqueline L. S. Milne and Sriram Subramaniam J. Virology, doi:10.1128/JVI.03284-12 (2013)
DRD2 polymorphisms modulate reward and emotion processing, dopamine neurotransmission and openness to experience Peciña M, Mickey BJ, Love T, Wang H, Langenecker SA, Hodgkinson C, Shen PH, Villafuerte S, Hsu D, Weisenbach SL, Stohler CS, Goldman D, Zubieta JK Cortex, doi: 10.1016/j.cortex.2012.01.010 (2013)

Prefrontal white matter impairment in substance users depends upon the catechol-o-methyl transferase (COMT) val158met polymorphism Zhang X, Lee MR, Salmeron BJ, Stein DJ, Hong LE, Geng X, Ross TJ, Li N, Hodgkinson C, Shen PH, Yang Y, Goldman D, Stein EA. Neuroimage, doi: 10.1016/j.neuroimage.2012.11.056 (2013)
The functional DRD3 Ser9Gly polymorphism (rs6280) is pleiotropic, affecting reward as well as movement Savitz J, Hodgkinson CA, Martin-Soelch C, Shen PH, Szczepanik J, Nugent A, Herscovitch P, Grace AA, Goldman D, Drevets WC. PLoS One, doi: 10.1371/journal.pone.0054108 (2013)
Association of genetic variation in pharmacodynamic factors with methadone dose required for effective treatment of opioid addiction Levran O, Peles E, Randesi M, Shu X, Ott J, Shen PH, Adelson M, Kreek MJ. Pharmacogenomics, doi: 10.2217/pgs.13.58 (2013)
Atomic-resolution structural information from scattering experiments on macromolecules in solution Jürgen Köfinger & Gerhard Hummer Phys. Rev. E , DOI:10.1103/PhysRevE.87.052712 (2013)
Evolutionary Pressure on the Topology of Protein Interface Interaction Networks Margaret E Johnson & Gerhard Hummer J. Phys. Chem. B, DOI: 10.1021/jp402944e (2013)
Genome-wide localization of exosome components to active promoters and chromatin insulators in Drosophila Lim SJ, Boyle PJ, Chinen M, Dale RK, Lei EP Nucleic Acids Research, doi: 10.1093/nar/gkt037 (2013)

A compendium of RNA-binding motifs for decoding gene regulation Ray D1, Kazan H, Cook KB, et al. Nature, doi: 10.1038/nature12311 (2013)
Messenger RNA is a functional component of a chromatin insulator complex Matzat LH1, Dale RK, Lei EP EMBO Rep., DOI: 10.1038/embor.2013.118 (2013)
Global analysis of the effects of the V2 receptor antagonist satavaptan on protein phosphorylation in collecting duct. Hoffert JD, Pisitkun T, Saeed F, Wilson JL, Knepper MA Am J Physiol Renal Physiol., DOI: 10.1152/ajprenal.00497.2013 (2013)
CAMS-RS: Clustering Algorithm for Large-Scale Mass Spectrometry Data Using Restricted Search Space and Intelligent Random Sampling Saeed F, Hoffert JD, Knepper MA IEEE/ACM Trans Comput Biol Bioinform., doi://10.1109/TCBB.2013.152 (2013)
A Genome-wide Map of CTCF Multivalency Redefines the CTCF Code Hirotaka Nakahashi, Kyong-Rim Kieffer Kwon, Wolfgang Resch, Laura Vian, Marei Dose, Diana Stavreva, Ofir Hakim, Nathanael Pruett, Steevenson Nelson, Arito Yamane, Jason Qian, Wendy Dubois, Scott Welsh, Robert D. Phair, B. Franklin Pugh, Victor Lobanenkov, Gordon L. Hager, and Rafael Casellas Cell Reports, doi://10.1016/j.celrep.2013.04.024 (2013)
Global Regulation of Promoter Melting in Naive Lymphocytes Fedor Kouzine, Damian Wojtowicz, Arito Yamane, Wolfgang Resch, Kyong-Rim Kieffer-Kwon, Russell Bandle, Steevenson Nelson, Hirotaka Nakahashi, Parirokh Awasthi, Lionel Feigenbaum, Herve Menoni, Jan Hoeijmakers, Wim Vermeulen, Hui Ge, Teresa M. Przytycka, David Levens, and Rafael Casellas Cell , doi://10.1016/j.cell.2013.04.033 (2013)
Therapeutic Response in Feline Sandhoff Disease Despite Immunity to Intracranial Gene Therapy Bradbury AM, Cochran JN, McCurdy VJ, Johnson AK et al Mol. Ther. , doi: 10.1038/mt.2013.86 (2013)
A next generation sequencing approach to constructing a genetic map for Populus tremula Tahir Mujtaba Master's Thesis, Swedish University of Agricultural Science (2013)
A 5′-Flanking Region of Gonadotropin-Regulated Testicular RNA Helicase (GRTH/DDX25) Gene Directs Its Cell-Specific Androgen-Regulated Gene Expression in Testicular Germ Cells Raghuveer Kavarthapu, Chon-Hwa Tsai-Morris, Masato Fukushima, James Pickel and Maria L. Dufau Endocrinology, doi: 10.1210/en.2012-2230 (2013)
Improving Peptide Identification Sensitivity in Shotgun Proteomics by Stratification of Search Space Gelio Alves and Yi-Kuo Yu J. Proteome Research, DOI: 10.1021/pr301139y (2013)
Strategies for recombinant protein production in maize Xing Xu PhD Thesis, Iowa State University (2013)
A simplified representation of anisotropic charge distributions within proteins Travis Hoppe J. Chem. Phys., doi://10.1063/1.4803099 (2013)
Proteomic Profiling and Pathway Analysis of the Response of Rat Renal Proximal Convoluted Tubules to Metabolic Acidosis Kevin L. Schauer, Dana M Freund, Jessica E. Prenni, and Norman P. Curthoys Renal Physiology, doi: 10.1152/ajprenal.00210.2013 (2013)
Three-Dimensional Structure of CAP-Gly Domain of Mammalian Dynactin Determined by Magic Angle Spinning NMR Spectroscopy: Conformational Plasticity and Interactions with End Binding Protein EB1 S. Yan, G. Hou, CD Schwieters, S Ahmed, JC Williams T Polenova J. Mol. Biol. , doi://10.1016/j.jmb.2013.04.027 (2013)
CG methylated microarrays identify a novel methylated sequence bound by the CEBPB| ATF4 heterodimer that is active in vivo Ishminder K. Mann, Raghunath Chatterjee, Jianfei Zhao et al. Genome Research, doi:10.1101/gr.146654.112 (2013)
Pointwise confidence intervals for a survival distribution with small samples or heavy censoring Michael P. Fay, Erica H. Brittain and Michael A. Proschan Biostatistics, doi: 10.1093/biostatistics/kxt016 (2013)
Degenerate polymerase chain reaction strategy with DNA microarray for detection of multiple and various subtypes of virus during blood screening K. Takizawa, T. Nakashima, T Mizukami et al. Transfusion, DOI: 10.1111/trf.12193 (2013)
Genome-wide association study of age at menarche in African-American women EW Demerath, C-T Liu, N Franceschini et al. Human Molecular Genetics, doi: 10.1093/hmg/ddt181 (2013)

Reconciling Mediating and Slaving Roles of Water in Protein Conformational Dynamics Li Zhao, Wenzhao Li, and Pu Tian PLoS One, doi://10.1371/journal.pone.0060553 (2013)
Vasopressin and the regulation of aquaporin-2 Justin L. L. Wilson, Carlos A. Miranda, Mark A. Knepper Clinical and Experimental Nephrology, doi://10.1007/s10157-013-0789-5 (2013)
Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: Systematic review and meta-analysis of 14 015 stroke cases and pooled analysis of primary biomarker data from up to 60 883 individuals TA Khan, T Shah, D Prieto et al. Int. J. Epidemiol. , doi: 10.1093/ije/dyt034 (2013)
Controlling the local false discovery rate in the adaptive Lasso Joshua N Sampson & Nilanjan Chatterjee Biostatistics, doi: 10.1093/biostatistics/kxt008 (2013)
Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli GA Snyder, C Cirl, J Jiang et al PNAS, doi: 10.1073/pnas.1215770110 (2013)
A crossed random effects modeling approach for estimating diagnostic accuracy from ordinal ratings without a gold standard Yunlong Xie, Zhen Chen, Paul S. Albert Statistics in Medicine, DOI: 10.1002/sim.5784 (2013)

Pharmacophore and 3D-QSAR Characterization of 6-arylquinazolin-4-amines as Cdc2-like kinase 4 (Clk4) and Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A (Dyrk1A) Inhibitors Yongmei Pan , Yanli Wang, and Stephen H. Bryant J. Chem. Inf. Model. , DOI: 10.1021/ci300625c (2013)
Effects of pre-existing anti-carrier immunity and antigenic element multiplicity on efficacy of a modular virus-like particle vaccine Yap P. Chuan, Tania Rivera-Hernandez, Nani Wibowo, Natalie K. Connors, Yang Wu, Fiona K. Hughes, Linda H. L. Lua, Anton P. J. Middelberg Biotech. & Bioengg. , DOI: 10.1002/bit.24907 (2013)
Global Analysis of Neuronal Phosphoproteome Regulation by Chondroitin Sulfate Proteoglycans Panpan Yu, Trairak Pisitkun, Guanghui Wang, Rong Wang, Yasuhiro Katagiri, Marjan Gucek, Mark A. Knepper, Herbert M. Geller PLoS One, doi:10.1371/journal.pone.0059285 (2013)
The alkaline pectate lyase PEL168 of Bacillus subtilis heterologously expressed in Pichia pastoris is more stable and efficient for degumming ramie fiber Chengjie Zhang, Jia Yao,Cheng Zhou,Liangwei Mao, Guimin Zhang, Yanhe Ma BMC Biotechnology, doi:10.1186/1472-6750-13-26 (2013)
In Silico, In Vitro, and In Vivo Studies Indicate the Potential Use of Bolaamphiphiles for Therapeutic siRNAs Delivery Taejin Kim, Kirill A. Afonin, Mathias Viard, Alexey Y Koyfman, Selene Sparks, Eliahu Heldman, Sarina Grinberg, Charles Linder, Robert P Blumenthal and Bruce A Shapiro Mol. Therapy - Nuc. Acids, doi:10.1038/mtna.2013.5 (2013)
RNAi triggered by specialized machinery silences developmental genes and retrotransposons Soichiro Yamanaka, Sameet Mehta, Francisca E. Reyes-Turcu, Fanglei Zhuang, Ryan T. Fuchs, Yikang Rong, Gregory B. Robb & Shiv I. S. Grewal Nature, doi:10.1038/nature11716 (2013)

Transcription-dependent dynamic supercoiling is a short-range genomic force Fedor Kouzine, Ashutosh Gupta, Laura Baranello, Damian Wojtowicz, Khadija Ben-Aissa, Juhong Liu, Teresa M Przytycka & David Levens Nature Structural & Molecular Biology, doi:10.1038/nsmb.2517 (2013)
X-Ray crystallographic structural characteristics of Arabidopsis hemoglobin I and their functional implications Nitika Mukhi, Sonali Dhindwal, Sheetal Uppal, Pravindra Kumar, Jagreet Kaur, Suman Kundu Biochim. et Biophys. Acta, doi://10.1016/j.bbapap.2013.02.024 (2013)
Engineering strategy to improve peptide analogs: from structure-based computational design to tumor homing David Zanuy, Francisco J. Sayago, Guillem Revilla-López, Gema Ballano, Lilach Agemy, Venkata Ramana Kotamraju, Ana I. Jiménez, Carlos Cativiela, Ruth Nussinov, April M. Sawvel, Galen Stucky, Erkki Ruoslahti, Carlos Alemán J. Computer-Aided Mol. Design, doi:10.1007/s10822-012-9623-5 (2013)
A novel taurocyamine kinase found in the protist Phytophthora infestans Kouji Uda, Michihiro Hoshijima, Tomohiko Suzuki Comp. Biochem. Phys. Part B: Biochem & Mol. Bio. , doi://10.1016/j.cbpb.2013.03.003 (2013)
Structure and accessibility of HA trimers on intact 2009 H1N1 pandemic influenza virus to stem region-specific neutralizing antibodies AK Harris, JR Meyerson, Y Matsuoka, O Kuybeda, A Moran, D Bliss, SR Das, JW Yewdell, G Sapiro, K Subbarao, and S Subramaniam PNAS, doi: 10.1073/pnas.1214913110 (2013)
Gene Synthesis by Assembly of Deoxyuridine-Containing Oligonucleotides Romualdas Vaisvila, Jurate Bitinaite Methods in Molecular Biology, doi: 10.1007/978-1-62703-293-3_12 (2013)

The Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of Calcineurin Simina Grigoriu, Rachel Bond, Pilar Cossio, Jennifer A. Chen, Nina Ly, Gerhard Hummer, Rebecca Page, Martha S. Cyert, Wolfgang Peti PLoS Biology, doi:10.1371/journal.pbio.1001492 (2013)
Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network Z Chen, H Tang, R Qayyum, UM Schick, MA Nalls et al. Human Molecular Genetics, doi: 10.1093/hmg/ddt087 (2013)
Common Variants Within Oxidative Phosphorylation Genes Influence Risk of Ischemic Stroke and Intracerebral Hemorrhage CD Anderson, A Biffi, MA Nalls, et al. & the International Stroke Genetics Consortium Stroke, doi: 10.1161/STROKEAHA.112.672089 (2013)
Antedependence models for nonstationary categorical longitudinal data with ignorable missingness likelihood-based inference Yunlong Xie, Dale Zimmerman Statistics in Medicine, DOI: 10.1002/sim.5763 (2013)
Sequence dependence of C-end rule peptides in binding and activation of neuropilin-1 receptor David Zanuy, Rohith Kotla, Ruth Nussinov, Tambet Teesalu, Kazuki N. Sugahara, Carlos Alemán, Nurit Haspel J. Struct. Biol. , doi://10.1016/j.jsb.2013.02.006 (2013)
Electrostatic spectral tuning mechanism of the green fluorescent protein Ville R. I. Kaila , Robert Send and Dage Sundholm Phys. Chem. Chem. Phys., DOI: 10.1039/C3CP00058C (2013)

Alzheimer's disease: Which type of amyloid-preventing drug agents to employ? Hyunbum Jang , Laura Connelly , Fernando Teran Arce , Srinivasan Ramachandran , Ratnesh Lal , Bruce L Kagan and Ruth Nussinov Phys. Chem. Chem. Phys., DOI: 10.1039/C3CP00017F (2013)
Control of breathing by interacting pontine and pulmonary feedback loops Yaroslav I. Molkov, Bartholomew J. Bacak, Thomas E. Dick, and Ilya A. Rybak Frontiers in Neural Circuits, doi: 10.3389/fncir.2013.00016 (2013)
Protein charge and mass contribute to the spatio-temporal dynamics of protein-protein interactions in a minimal proteome Yu Xu, Hong Wang, Ruth Nussinov, Buyong Ma Proteomics, DOI: 10.1002/pmic.201100540 (2013)
Differential requirements for mRNA folding partially explain why highly expressed proteins evolve slowly C Park, X Chen, J-R Yang, J Zhang PNAS, doi: 10.1073/pnas.1218066110 (2013)
The Val158Met COMT polymorphism is a modifier of the age at onset in Parkinson's disease with a sexual dimorphism S Klebe, J-L Golmard, MA Nalls et al, French Parkinson's Disease Genetics Study Group and the International Parkinson's Disease Genomics Consortium J Neurol Neurosurg Psychiatry , doi:10.1136/jnnp-2012-304475 (2013)
The Convergence of Maturational Change and Structural Covariance in Human Cortical Networks Aaron Alexander-Bloch, Armin Raznahan, Ed Bullmore, and Jay Giedd J. Neuroscience , doi: 10.1523/JNEUROSCI.3554-12.2013 (2013)

Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer Li-Jun Di, Jung S. Byun, Madeline M. Wong, Clay Wakano, Tara Taylor, Sven Bilke, Songjoon Baek, Kent Hunter, Howard Yang, Maxwell Lee, Cecilia Zvosec, Galina Khramtsova, Fan Cheng, Charles M. Perou, C. Ryan Miller, Rachel Raab, Olufunmilayo I. Olopade & Kevin Gardner Nature Communications, doi:10.1038/ncomms2438 (2013)
Ischemic stroke is associated with the ABO locus: The EuroCLOT study FMK Williams, AM Carter, PG Hysi et al and EuroCLOT Investigators, the Wellcome Trust Case Control Consortium 2, MORGAM, MetaStroke and the International Stroke Genetics Consortium Annals of Neurology, DOI: 10.1002/ana.23838 (2013)
Initial Assessment of the Pathogenic Mechanisms of the Recently Identified Alzheimer Risk Loci P Holton, M Ryten, MA Nalls et al. Annals of Human Genetics, DOI: 10.1111/ahg.12000 (2013)
Alternative Complex III from phototrophic bacteria and its electron acceptor auracyanin Erica L.W. Majumder, Jeremy D. King, Robert E. Blankenship Biochim. et Biophys. Acta - Bioenergetics, doi://10.1016/j.bbabio.2013.01.008 (2013)
Identification of Early Replicating Fragile Sites that Contribute to Genome Instability JH Barlow, RB Faryabi, E Callen, N Wong, A Malhowski, H Tang Chen, G Gutierrez-Cruz, H-W Sun, P McKinnon, G Wright, R Casellas, DF Robbiani, L Staudt, O Fernandez-Capetillo, A Nussenzweig Cell, doi://10.1016/j.cell.2013.01.006 (2013)
Genetic variation associated with circulating monocyte count in the eMERGE Network DR Crosslin, A McDavid, N Weston et al Hum. Mol. Genetics, doi: 10.1093/hmg/ddt010 (2013)

PI(4,5)P2-Mediated Cell Signaling: Emerging Principles and PTEN as a Paradigm for Regulatory Mechanism Arne Gericke, Nicholas R. Leslie, Mathias Lösche, Alonzo H. Ross Adv Exp Med Biol, doi: 10.1007/978-94-007-6331-9_6 (2013)

2012 (146 papers)

An efficient algorithm for clustering of large-scale mass spectrometry data Saeed F, Pisitkun T, Knepper MA, Hoffert JD Proceedings (IEEE Int Conf Bioinformatics Biomed), doi://10.1109/BIBM.2012.6392738 (2012)
A Dual Polybasic Motif Determines Phosphoinositide Binding and Regulation in the P2X Channel Family Louis-Philippe Bernier, Dominique Blais, É ́ric Boué-Grabot, Philippe Séguéla PLoS One 7:1-9, doi: 10.1371/journal.pone.0040595 (2012)
Estimating Diagnostic Accuracy of Raters Without a Gold Standard by Exploiting a Group of Experts Zhang B, Chen Z, Albert PS. Biometrics, doi: 10.1111/j.1541-0420.2012.01789.x (2012)
Entropy of single-file water in (6,6) carbon nanotubes Aparna Waghe, Jayendran C. Rasaiah, and Gerhard Hummer J. Chem. Phys. , doi://10.1063/1.4737842 (2012)
Assessment of the Effect of 24-Hour Aldosterone Administration on Protein Abundance in Fluorescence-Sorted Mouse Distal Renal Tubules by Mass Spectrometry Jensen T.B., Pisitkun T., Hoffert J.D., Jensen U.B., Fenton R.A, Praetorius H.A, Knepper M.A, Praetorius J. Nephron Physiology, DOI:10.1159/000346832 (2012)
On the Origins of the Linear Free Energy Relationships: Exploring the Nature of the Off-Diagonal Coupling Elements in SN2 Reactions Edina Rosta and Arieh Warshal J Chem Theory Comput. , doi: 10.1021/ct2009329 (2012)
An efficient dynamic programming algorithm for phosphorylation site assignment of large-scale mass spectrometry data Fahad Saeed, Trairak Pisitkun, Jason D. Hoffert, Guanghui Wang, Marjan Gucek, and Mark A. Knepper Proceedings of IEEE Int Conf Bioinformatics Biomed, doi://10.1109/BIBMW.2012.6470210 (2012)
Cell population-specific expression analysis of human cerebellum A Kuhn, A Kumar, A Beilina, A Dillman, MR Cookson, AB Singleton BMC Genomics, doi:10.1186/1471-2164-13-610 (2012)
Both Genome Segments Contribute to the Pathogenicity of Very Virulent Infectious Bursal Disease Virus Olivier Escaffre, Cyril Le Nouën, Michel Amelot, Xavier Ambroggio, Kristen M. Ogden, Olivier Guionie, Didier Toquin, Hermann Müller, Mohammed R. Islam and Nicolas Eterradossi J. Virology, doi: 10.1128/JVI.02360-12 (2012)
Using dissociation energies to predict observability of b- and y-peaks in mass spectra of short peptides. II. Results for hexapeptides with non-polar side chains O. I. Obolensky, Wells W. Wu, Rong-Fong Shen, Yi-Kuo Yu Rapid Comm. in Mass. Spec., DOI: 10.1002/rcm.6451 (2012)
Melatonin inhibits matrix metalloproteinase-9 activity by binding to its active site Deep Sankar Rudra, Uttam Pal, Nakul Chandra Maiti, Russel J. Reiter, Snehasikta Swarnakar J. Pineal Research, DOI: 10.1111/jpi.12034 (2012)

RPA Accumulation during Class Switch Recombination Represents 5'-3' DNA-End Resection during the S-G2/M Phase of the Cell Cycle Arito Yamane, Davide F. Robbiani, Wolfgang Resch, Anne Bothmer, Hirotaka Nakahashi, Thiago Oliveira, Philipp C. Rommel, Eric J. Brown, Andre Nussenzweig, Michel C. Nussenzweig, Rafael Casellas Cell Reports, doi://10.1016/j.celrep.2012.12.006, (2012)
Molecular structures of trimeric HIV-1 Env in complex with small antibody derivatives Joel R. Meyerson, Erin E. H. Tran, Oleg Kuybeda, Weizao Chen, Dimiter S. Dimitrov, Andrea Gorlani, Theo Verrips, Jeffrey D. Lifson, and Sriram Subramaniam PNAS, doi:10.1073/pnas.1214810110 (2012)
Effect of compatible and noncompatible osmolytes on the enzymatic activity and thermal stability of bovine liver catalase H. Sepasi Tehrani, A.A. Moosavi-Movahedia, H. Ghourchian, F. Ahmad, A. Kiany, M.S. Atri, Sh Ariaeenejad, K. Kavousi & A.A. Sabourya J. Biomol. Struct. Dynamics, DOI:10.1080/07391102.2012.742460 (2012)
RNA Interference Mediated Inhibition of Dengue Virus Multiplication and Entry in HepG2 Cells MA Alhoot, SM Wang, SD Sekaran PLoS One, RNA Interference Mediated Inhibition of Dengue Virus Multiplication and Entry in HepG2 Cells (2012)
On the edge of web-based multiple sequence alignment services Nguyen, Ken D. Tsinghua Science and Technology 17(6):629-637 (2012)
Using dissociation energies to predict observability of b- and y-peaks in mass spectra of short peptides. O. I. Obolensky, Wells W. Wu, Rong-Fong Shen, Yi-Kuo Yu Rapid Comm. in Mass. Spec., DOI: 10.1002/rcm.6451 (2012)

Mechanisms for the Insertion of Toxic, Fibril-like β-Amyloid Oligomers into the Membrane Hyunbum Jang , Laura Connelly , Fernando Teran Arce , Srinivasan Ramachandran , Bruce L. Kagan , Ratnesh Lal , and Ruth Nussinov J. Chem. Theory Compt. , DOI: 10.1021/ct300916f (2012)
Structural Ensemble of an Intrinsically Disordered Polypeptide Jeetain Mittal , Tae Hyeon Yoo , George Georgiou , and Thomas Michael Truskett J. Phys. Chem. B, DOI: 10.1021/jp308984e (2012)
STATs Shape the Active Enhancer Landscape of T Cell Populations Golnaz Vahedi, Hayato Takahashi, Shingo Nakayamada, Hong-wei Sun, Vittorio Sartorelli, Yuka Kanno, John J. O'Shea Cell, doi://10.1016/j.cell.2012.09.044, (2012)
Screening system for orthogonal suppressor tRNAs based on the species-specific toxicity of suppressor tRNAs Hong Tian, Danni Deng, Jie Huang, Dongning Yao, Xiaowei Xu, Xiangdong Gao Biochimie, doi://10.1016/j.biochi.2012.12.010 (2012)
Structural and Mechanistic Investigations of Phosphothreonine Lyase Class of Enzymes Alok Gopalkrishna Shenoy Graduate Thesis, Utah State University (2012)
Evaluation of Gene Association Methods for Coexpression Network Construction and Biological Knowledge Discovery Sapna Kumari, Jeff Nie, Huann-Sheng Chen, Hao Ma, Ron Stewart, Xiang Li, Meng-Zhu Lu, William M. Taylor, Hairong Wei PLoS One, doi:10.1371/journal.pone.0050411 (2012)
Common genetic variation near the Connexin-43 gene is associated with resting heart rate in African Americans: A Genome-wide Association Study of 13,372 participants R Deo, MA Nalls, CL Avery, JG Smith et al. Heart Rhythm, doi://10.1016/j.hrthm.2012.11.014 (2012)
Protein Secondary Structure Determination by Constrained Single-Particle Cryo-Electron Tomography Alberto Bartesaghi, Federico Lecumberry, Guillermo Sapiro, Sriram Subramaniam Structure 20(12):2003-2013 (2012)
A Systematic Approach for Development of an OPLS-Like Force Field and Its Application to Hydrofluorocarbons Eugene Paulechka , Kenneth Kroenlein , Andrei Kazakov , and Michael Frenkel J. Phys. Chem. B, DOI: 10.1021/jp309119h (2012)
The Impact of Ancestry and Common Genetic Variants on QT Interval in African Americans JG Smith, CL Avery, DS Evans, MA Nalls et al. Circulation: Cardiovascular Genetics, doi: 10.1161/CIRCGENETICS.112.962787 (2012)
The effect of spatial smoothing on fMRI decoding of columnar-level organization with linear support vector machine Masaya Misaki, Wen-Ming Luh, Peter A. Bandettini J. Neuroscience Methods, doi://10.1016/j.jneumeth.2012.11.004 (2012)
Candidate Gene Association Study of BMI-Related Loci, Weight, and Adiposity in Old Age Rachel A. Murphy, Michael A. Nalls, Margaux Keller, Melissa Garcia, Stephen B. Kritchevsky, Frances A. Tylavsky, Anne B. Newman, Gregory J. Tranah, Gudny Eiriksdottir, Vilmundur Gudnason and Tamara B. Harris J. Gerontology A, doi: 10.1093/gerona/gls227 (2012)

Conformational Exploration of Two Peptides and Their Hybrid Polymer Conjugates: Potentialities as Self-Aggregating Materials Nurit Haspel, Adéle D. Laurent, David Zanuy , Ruth Nussinov, Carlos Aleman, Jordi Puiggali, and Guillermo Revilla-López J. Phys. Chem. B, DOI: 10.1021/jp3043363 (2012)
Watching a signaling protein function in real time via 100-ps time-resolved Laue crystallography F Schotte, HS Cho, VRI Kaila, H Kamikubo, N Dashdorj, ER Henry, TJ Graber, R Henning, M Wulff, G Hummer, M Kataoka, and PA Anfinrud PNAS, doi: 10.1073/pnas.1210938109 (2012)
Effects of the BDNF Val66Met Polymorphism on White Matter Microstructure in Healthy Adults H Tost, T Alam, M Geramita, C Rebsch, B Kolachana, D Dickinson, BA Verchinski, H Lemaitre, AS Barnett, JW Trampush, DR Weinberger and S Marenco Neuropsychopharmacology , doi: 10.1038/npp.2012.214 (2012)
Sodium and calcium mechanisms of rhythmic bursting in excitatory neural networks of the pre-Bötzinger complex: a computational modelling study Patrick E. Jasinski, Yaroslav I. Molkov, Natalia A. Shevtsova, Jeffrey C. Smith, Ilya A. Rybak Eur. J. Neuroscience, DOI: 10.1111/ejn.12042 (2012)
Effects of image contrast on functional MRI image registration Javier Gonzalez-Castillo, Kristen N. Duthie, Ziad S. Saad, Carlton Chu, Peter A. Bandettini, Wen-Ming Luh NeuroImage, doi://10.1016/j.neuroimage.2012.10.076 (2012)
Accurate decoding of sub-TR timing differences in stimulations of sub-voxel regions from multi-voxel response patterns Masaya Misaki, Wen-Ming Luh, Peter A. Bandettini NeuroImage, doi://10.1016/j.neuroimage.2012.10.069, (2012)

Novel Loci Associated with PR Interval in a Genome-Wide Association Study of Ten African American Cohorts AM Butler, X Yin, DS Evans, MA Nalls et al. Circulation: Cardiovascular Genetics, doi: 10.1161/CIRCGENETICS.112.963991 (2012)
Response of the Mitochondrial Proteome of Rat Renal Proximal Convoluted Tubules to Chronic Metabolic Acidosis D Freund, JE Prenni, NP Curthoys Renal Physiology, ,doi: 10.1152/ajprenal.00526.2012 (2012)
PTEN: An Intercellular Peacekeeper? Nick R. Leslie Science Signaling, DOI: 10.1126/scisignal.2003685 (2012)
Gene Silencing Mediated by siRNA-binding Fusion Proteins Is Attenuated by Double-stranded RNA-binding Domain Structure James C Geoghegan, Brian L Gilmore and Beverly L Davidson Molecular Therapy Nucleic Acids, doi:10.1038/mtna.2012.43 (2012)
A collaborative framework for 3D alignment and classification of heterogeneous subvolumes in cryo-electron tomography Oleg Kuybeda, Gabriel A. Frank, Alberto Bartesaghi, Mario Borgnia, Sriram Subramaniam , Guillermo Sapiro J. Struct. Biol. , doi://10.1016/j.jsb.2012.10.010 (2012)
Novel inhibitors of a Grb2 SH3C domain interaction identified by a virtual screen Philip C. Simister, James Luccarelli, Sam Thompson, Daniel H. Appella, Stephan M. Feller , Andrew D. Hamilton Bioorganic & Medicinal Chemistry, doi://10.1016/j.bmc.2012.10.023 (2012)

Statistical tests for detecting associations with groups of genetic variants: generalization, evaluation, and implementation John Ferguson, William Wheeler, YiPing Fu, Ludmila Prokunina-Olsson, Hongyu Zhao and Joshua Sampson Eur. J. Hum. Genetics, doi: 10.1038/ejhg.2012.220 (2012)
Imputation of Exome Sequence Variants into Population- Based Samples and Blood-Cell-Trait-Associated Loci in African Americans: NHLBI GO Exome Sequencing Project Paul L. Auer, Jill M. Johnsen, Andrew D. Johnson et al. Am. J. Hum. Genet., doi://10.1016/j.ajhg.2012.08.031 (2012)
SHAVE: shrinkage estimator measured for multiple visits increases power in GWAS of quantitative traits Osorio D Meirelles, Jun Ding, Toshiko Tanaka, Serena Sanna, Hsih-Te Yang, Dawood B Dudekula, Francesco Cucca, Luigi Ferrucci, Goncalo Abecasis and David Schlessinger European J. Hum. Genetics, doi: 10.1038/ejhg.2012.215 (2012)
Membrane Association of the PTEN Tumor Suppressor: Electrostatic Interaction with Phosphatidylserine-Containing Bilayers and Regulatory Role of the C-Terminal Tail Siddharth S. Shenoy, Hirsh Nanda, c, Mathias Lösche J. Struct. Biol. , doi://10.1016/j.jsb.2012.10.003, (2012)
Characterization of synonymous codon usage bias in the pseudorabies virus US1 gene Meili Li, Zhiyao Zhao, Jianhong Chen, Bingyun Wang, Zi Li, Jian Li and Mingsheng Cai Virologica Sinica, DOI: 10.1007/s12250-012-3270-9 (2012)
Overlapping ETS and CRE Motifs (G/CCGGAAGTGACGTCA) Preferentially Bound by GABPα and CREB Proteins Raghunath Chatterjee, Jianfei Zhao, Ximiao He, Andrey Shlyakhtenko, Ishminder Mann, Joshua J. Waterfall, Paul Meltzer, B. K. Sathyanarayana, Peter C. FitzGerald, Charles Vinson Genes | Genomes | Genetics, doi://10.1534/g3.112.004002 (2012)

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies M Traylor, M Farrall, EG Holliday et al & International Stroke Genetics Consortium The Lancet Neurology, doi://10.1016/S1474-4422(12)70234-X, (2012)
Siblings with Ischemic Stroke Study (SWISS): Results of a Genome-wide Scan for Stroke Loci JF. Meschia, M Nalls, M Matarin, TG. Brott, RD. Brown, Jr., J Hardy, B Kissela, SS. Rich, A Singleton, D Hernandez, L Ferrucci, K Pearce, M Keller, BB. Worrall, for the Siblings with Ischemic Stroke Study (SWISS) Investigators Stroke, doi: 10.1161/STROKEAHA.111.620484 (2012)
Effect of Complement CR1 on Brain Amyloid Burden During Aging and Its Modification byAPOEGenotype M Thambisetty, Y An, M Nalls et al for the Baltimore Longitudinal Study of Aging and the Alzheimer's Disease Neuroimaging Initiative Biological Psychiatry, doi://10.1016/j.biopsych.2012.08.015 (2012)
CPhos: a program to calculate and visualize evolutionarily conserved functional phosphorylation sites Boyang Zhao, Trairak Pisitkun, Jason D. Hoffert, Mark A. Knepper, Fahad Saeed Proteomics, DOI: 10.1002/pmic.201200189 (2012)
Quantitative Phosphoproteomics in Nuclei of Vasopressin-Sensitive Renal Collecting Duct Cells Steven J. Bolger, Patricia A. Gonzales Hurtado, Jason D. Hoffert, Fahad Saeed, Trairak Pisitkun, and Mark A. Knepper Am J Physiol Cell Physiol, doi:10.1152/ajpcell.00260.2012 (2012)
Are Myocardial Infarction-Associated Single-Nucleotide Polymorphisms Associated With Ischemic Stroke? Cheng YC, Anderson CD, Bione S et al Stroke, doi: 10.1161/STROKEAHA.111.632075 (2012)

Lin28b Reprograms Adult Bone Marrow Hematopoietic Progenitors to Mediate Fetal-Like Lymphopoiesis Joan Yuan, Cuong K. Nguyen, Xiuhuai Liu, Chrysi Kanellopoulou, Stefan A. Muljo Science 335 (6073):1195-1200 (2012)
The development and application of transposon mutagenesis and unnatural amino acid mutagenesis technologies Jia Liu Ph.D Thesis, U. Maryland (2012)
Mouse model of endemic Burkitt translocations reveals the long-range boundaries of Ig-mediated oncogene deregulation AL Kovalchuk, C Ansarah-Sobrinho, O Hakim, W Resch, Helena Tolarová, W Dubois, A Yamane, M Takizawa, IKlein, GL Hager, HC Morse III, M Potter, MC Nussenzweig, and R Casellas PNAS, doi: 10.1073/pnas.1200106109 (2012)
Testing associations of copy number variations in genome-wide association studies Jianxin Shi and Peng Li Statistica Sinica, doi://10.5705/ss.2012.071s (2012)
Systems Biology in Physiology: The Vasopressin Signaling Network in Kidney Mark A. Knepper Am. J. Physiol. - Cell Physiol. , doi: 10.1152/ajpcell.00270.2012 (2012)
Comparing the Expected Misclassification Cost for Two Classifiers Based on Estimates From the Same Sample James F. Troendle, Kai F. Yu, Peter H. Westfall, Gene Pennello & Enrique F. Schisterman Statistics in Biopharmaceutical Research, DOI:10.1080/19466315.2012.695263 (2012)

Theory for cross effect dynamic nuclear polarization under magic-angle spinning in solid state nuclear magnetic resonance: The importance of level crossings Kent Thurber and Robert Tycko J. Chem. Phys. , doi://10.1063/1.4747449 (2012)
Prediction of variable translation rate effects on cotranslational protein folding Edward P. O'Brien, Michele Vendruscolo & Christopher M. Dobson Nature Communications, doi:10.1038/ncomms1850 (2012)
Directed evolution reveals requisite sequence elements in the functional expression of P450 2F1 in Escherichia coli JBYH Behrendorff, CD Moore, K-H Kim, D-H Kim, CA Smith, WA Johnston, C-H Yun, GS Yost, and EMJ Gillam Chemical Research in Toxicology, DOI: 10.1021/tx300281g (2012)
Using Genome-wide Complex Trait Analysis to quantify 'missing heritability' in Parkinson's disease MF Keller, M Saad, et al and International Parkinson's Disease Genomics Consortium and the Wellcome Trust Case Control Consortium 2 Human Molecular Genetics, doi: 10.1093/hmg/dds335 (2012)
Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics R Schmitz, RM Young et al Nature, doi:10.1038/nature11378 (2012)
Automated subcortical segmentation using FIRST: Test-retest reliability, interscanner reliability, and comparison to manual segmentation Allison C. Nugent, David A. Luckenbaugh, Suzanne E. Wood, Wendy Bogers, Carlos A. Zarate Jr., Wayne C Drevets Human Brain Mapping, DOI: 10.1002/hbm.22068 (2012)

Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone φ, ψ and Side-Chain χ1 and χ2 Dihedral Angles Robert B. Best, Xiao Zhu, Jihyun Shim, Pedro E. M. Lopes, Jeetain Mittal, Michael Feig, and Alexander D. MacKerell, Jr. J. Chem. Theory Comput., DOI: 10.1021/ct300400x (2012)
Profibrogenic chemokines and viral evolution predict rapid progression of hepatitis C to cirrhosis Patrizia Farci, Kurt Wollenberg, Giacomo Diaz, Ronald E. Engle, Maria Eliana Lai, Paul Klenerman, Robert H. Purcell, Oliver G. Pybus, and Harvey J. Alter PNAS, doi: 10.1073/pnas.1210592109 (2012)
Multiple Testing of Composite Null Hypotheses in Heteroscedastic Models Wenguang Sun & Alexander C. McLain Journal of the American Statistical Association 107(498):637-687 (2012)
Use of support vector machines for disease risk prediction in genome-wide association studies: Concerns and opportunities F Mittag, F Büchel, M Saad, A Jahn, C Schulte, Z Bochdanovits, J Simón-Sánchez, MA Nalls, M Keller, DG Hernandez, JR Gibbs, S Lesage, A Brice, P Heutink, M Martinez, NW Wood, J Hardy, AB Singleton, A Zell, T Gasser, M Sharma for the International Parkinson's Disease Genomics Consortium (IPDGC) Human Mutation, DOI: 10.1002/humu.22161 (2012)
Drying Transition in the Hydrophobic Gate of the GLIC Channel Blocks Ion Conduction Fangqiang Zhu and Gerhard Hummer Biophys. J. 103(2):219-227, doi://10.1016/j.bpj.2012.06.003 (2012)
Structural Mechanism of Trimeric HIV-1 Envelope Glycoprotein Activation Erin E. H. Tran, Mario J. Borgnia, Oleg Kuybeda, David M. Schauder, Alberto Bartesaghi, Gabriel A. Frank, Guillermo Sapiro, Jacqueline L. S. Milne, Sriram Subramaniam PLoS Pathogens, doi:10.1371/journal.ppat.1002797 (2012)
The impact of random-effect misspecification on percentile estimation for longitudinal growth data Kyeongmi Cheon, Paul S. Albert, Zhiwei Zhang Statistics in Medicine, DOI: 10.1002/sim.5437 (2012)
Mitochondrial DNA Sequence Variation Associated with Dementia and Cognitive Function in the Elderly Tranah GJ, Nalls MA, Katzman SM, Yokoyama JS, Lam ET, Zhao Y, Mooney S, Thomas F, Newman AB, Liu Y, Cummings SR, Harris TB, Yaffe K J. Alzheimer's Disease, doi://10.3233/JAD-2012-120466 (2012)
Weighted logrank tests for interval censored data when assessment times depend on treatment Michael P. Fay, Joanna H. Shih Statistics in Medicine, DOI: 10.1002/sim.5447 (2012)
Genetic Contributions to Individual Differences in Vulnerability to Addiction and Abilities to Quit George R. Uhl and Tomas Drgon in Drug Abuse and Addiction in Mental Illness, DOI: 10.1007/978-1-4614-3375-0-7 (2012)
Understanding Neuroplastic Effects of Transcranial Direct Current Stimulation through Analysis of Dynamics of Large-Scale Brain Networks Anusha Venkatakrishnan Ph.D. Thesis, University of Maryland (2012)
Design and Assembly of Large Synthetic DNA Constructs Aleksandr E. Miklos, Randall A. Hughes, Andrew D. Ellington Current Protocols in Molecular Biology, DOI: 10.1002/0471142727.mb0323s99 (2012)

Leptin regulates dopamine responses to sustained stress in humans Paul R Burghardt, Tiffany M Love, Christian S. Stohler, Colin Hodgkinson, Pei-Hong Shen, Mary Ann Enoch, David Goldman, Jon-Kar Zubieta J. Neurosci. , doi: 10.1523/JNEUROSCI.2521-12.2012 (2012)
Estimating ancestral proportions in a multi-ethnic US sample: implications for studies of admixed populations Orna Levran, Olaoluwakitan Awolesi, Pei-Hong Shen, Miriam Adelson, and Mary Jeanne Kreek Human Genomics, doi: 10.1186/1479-7364-6-2 (2012)
The Peptide-Receptive Transition State of MHC Class I Molecules: Insight from Structure and Molecular Dynamics Michael G. Mage, Michael A. Dolan, Rui Wang, Lisa F. Boyd, Maria Jamela Revilleza, Howard Robinson, Kannan Natarajan, Nancy B. Myers, Ted H. Hansen and David H. Margulies J. Immunol. , doi: 10.4049/jimmunol.1200831 (2012)
The Folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for B cell development Baba M, Keller JR, Sun HW, Resch W, Kuchen S, Suh HC, Hasumi H, Hasumi Y, Kieffer-Kwon KR, Gonzalez CG, Hughes RM, Klein ME, Oh HF, Bible P, Southon E, Tessarollo L, Schmidt LS, Linehan WM, Casellas R. Blood, DOI 10.1182/blood-2012-02-410407 (2012)
Identifying Protein Kinase Target Preferences Using Mass Spectrometry Jacqueline Douglass, Ruwan Gunaratne, Davis Bradford, Fahad Saeed, Jason D. Hoffert, Peter J. Steinbach, Mark A. Knepper, and Trairak Pisitkun Cell Physiol., doi: 10.1152/ajpcell.00166.2012 (2012)
Improving the CHARMM Force Field for Polyunsaturated Fatty Acid Chains Jeffery B. Klauda, Viviana Monje, Taehoon Kim, and Wonpil Im J. Phys. Chem. B, DOI: 10.1021/jp304056p (2012)

Crystal structure of a plectonemic RNA supercoil Jason R. Stagno, Buyong Ma, Jess Li, Amanda S. Altieri, R. Andrew Byrd & Xinhua Ji Nature Communications, doi:10.1038/ncomms1903 (2012)
Codon optimization for high level expression of human bone morphogenetic protein-2 in Escherichia coli Debbie S. Retnoningruma, H.T. Pramestia, P.Y. Santikaa, O. Valeriusb, S. Asjariea, T. Suciatia Prot. Expr. and Pur., doi://10.1016/j.pep.2012.05.010 (2012)
Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases Sarah Baxter, Abigail R. Lambert, Ryan Kuhar, Jordan Jarjour, Nadia Kulshina, Fabio Parmeggiani, Patrick Danaher, Jacob Gano, David Baker, Barry L. Stoddard and Andrew M. Scharenberg Nucleic Acids Research, doi: 10.1093/nar/gks502 (2012)
Trigger factor slows co-translational folding through kinetic trapping while sterically protecting the nascent chain from aberrant cytosolic interactions Edward P O'Brien, John Christodoulou, Michele Vendruscolo, and Christopher M. Dobson J. Am. Chem. Soc. , DOI: 10.1021/ja302305u (2012)
Genomic Analysis of Immune Response against Vibrio cholerae Hemolysin in Caenorhabditis elegans Surasri N. Sahu, Jada Lewis, Isha Patel, Serdar Bozdag, Jeong H. Lee, Joseph E. LeClerc, and Hediye Nese Cinar PLoS One, doi: 10.1371/journal.pone.0038200 (2012)
Spontaneous High-Gamma Band Activity Reflects Functional Organization of Auditory Cortex in the Awake Macaque Makoto Fukushima, Richard C. Saunders, David A. Leopold, Mortimer Mishkin, and Bruno B. Averbeck Neuron, DOI 10.1016/j.neuron.2012.04.014 (2012)

Mitochondrial DNA sequence variation is associated with free-living activity energy expenditure in the elderly Gregory J. Tranah, Ernest T. Lam, Shana M. Katzman, Michael A. Nalls, Yiqiang Zhao, Daniel S. Evans, Jennifer S. Yokoyama, Ludmila Pawlikowska, Pui-Yan Kwok, Sean Mooney, Stephen Kritchevsky, Bret H. Goodpaster, Anne B. Newman, Tamara B. Harris, Todd M. Manini, Steven R. Cummings, For the Health, Aging and Body Composition Study Biochim. et Biophys. Acta - Bioenergetics, doi://10.1016/j.bbabio.2012.05.012 (2012)
An online tool for calculation of free-energy balance for the renal inner medulla Ryan L. Vilbig, Abhijit Sarkar, Joseph Zischkau, Mark A. Knepper, and Trairak Pisitkun Am. J. Physiol. , doi: 10.1152/ajprenal.00147.2012 (2012)
Application of systems biology principles to protein biomarker discovery: Urinary exosomal proteome in renal transplantation Trairak Pisitkun, Maria T. Gandolfo, Samarjit Das, Mark A. Knepper, Serena M. Bagnasco Proteomics -- Clinical Applications, doi://10.1002/prca.201100108 (2012)
Methods of adjusted comparison of medians James F. Troendle, Zhiwei Zhang, Megan E. Mathews, Junchi Guo Biometrical Journal, DOI: 10.1002/bimj.201100220 (2012)
Characterization of a Dynamic String Method for the Construction of Transition Pathways in Molecular Reactions Margaret E. Johnson and Gerhard Hummer J. Phys. Chem. B, DOI: 10.1021/jp212611k (2012)
Tissue-Specific Regulation of Chromatin Insulator Function Leah H. Matzat, Ryan K. Dale, Nellie Moshkovich, and Elissa P. Lei PLoS Genetics, doi: 10.1371/journal.pgen.1003069 (2012)

A Subset-Based Approach Improves Power and Interpretation for the Combined Analysis of Genetic Association Studies of Heterogeneous Traits Samsiddhi Bhattacharjee, Preetha Rajaraman, Kevin B. Jacobs, William A. Wheeler, Beatrice S. Melin, Patricia Hartge, GliomaScan Consortium, Meredith Yeager, Charles C. Chung, Stephen J. Chanock, Nilanjan Chatterjee Am. J. Hum. Genet., doi:/10.1016/j.ajhg.2012.03.015 (2012)
Seeing is believing: video classification for computed tomographic colonography using multiple-instance learning. Shijun Wang, Matthew T McKenna, Tan B Nguyen, Joseph E Burns, Nicholas Petrick, Berkman Sahiner, Ronald M Summers IEEE Transactions on Medical Imaging 31 (5):1141 (2012)
Cross-seeding and Conformational Selection between Three- and Four-repeat Human Tau Proteins Xiang Yu, Yin Luo, Paul Dinkel, Jie Zheng, Guanghong Wei, Martin Margittai, Ruth Nussinov, Buyong Ma J. Biol. Chem., doi: 10.1074/jbc.M112.340794 (2012)
An Integrative Segmentation Method for Detecting Germline Copy Number Variations in SNP Arrays Jianxin Shi, Peng Li Genetic Epidemiology 36(4):373-383, DOI: 10.1002/gepi.21631 (2012)
Structural and Functional Consequences of Phosphate-Arsenate Substitutions in Selected Nucleotides: DNA, RNA, and ATP Yu Xu, Buyong Ma, and Ruth Nussinov J. Phys. Chem. B, doi: 10.1021/jp300307u (2012)
Imino Hydrogen Positions in Nucleic Acids from Density Functional Theory Validated by NMR Residual Dipolar Couplings Alexander Grishaev, Jinfa Ying, Ad Bax J. Am. Chem. Soc., doi: 10.1021/ja301775j (2012)
The transcriptome of Spodoptera exigua larvae exposed to different types of microbes Laura Pascual, Agata K. Jakubowska, Jose M. Blanca, Joaquin Cañizares, Juan Ferré, Gernot Gloeckner, Heiko Vogel, Salvador Herrero Insect Biochem. Mol. Bio. , doi://10.1016/j.ibmb.2012.04.003 (2012)
A Two-Platform Design for Next Generation Genome-Wide Association Studies Joshua N. Sampson, Kevin Jacobs, Zhaoming Wang, Meredith Yeager, Stephen Chanock, Nilanjan Chatterjee Genetic Epidemiology, doi: 10.1002/gepi.21634 (2012)
Postnatal development-and age-related changes in DNA-methylation patterns in the human genome Paraskevi Salpea, Valya R. Russanova, Tazuko H. Hirai, Thomae G. Sourlingas, Kalliope E. Sekeri-Pataryas, Roberto Romero, Jonathan Epstein and Bruce H. Howard Nucleic Acids Research, doi: 10.1093/nar/gks312 (2012)
Restraints on backbone conformations in solid state NMR studies of uniformly labeled proteins from quantitative amide¹⁵N-¹⁵N and carbonyl ¹³C-¹³C dipolar recoupling data Kan-Nian Hua, Wei Qiang, Guillermo A. Bermejo, Charles D. Schwieters, Robert Tycko J. Magnetic Resonance, doi:10.1016/j.jmr.2012.03.001 (2012)
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis The Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium Lancet, doi: 10.1016/S0140-6736(12)60110-X (2012)
Distinct contributions of human hippocampal theta to spatial cognition and anxiety Brian R. Cornwell, Nicole Arkin, Cassie Overstreet, Frederick W. Carver, Christian Grillon Hippocampus, doi: 10.1002/hipo.22019 (2012)

Simple models of human brain functional networks Petra E. Vértes, Aaron F. Alexander-Bloch, Nitin Gogtay, Jay N. Giedd, Judith L. Rapoport, and Edward T. Bullmore PNAS, doi: 10.1073/pnas.1111738109 (2012)
Computational tools for metabolic engineering Wilbert B. Copeland, Bryan A. Bartley, Deepak Chandran, Michal Galdzicki, Kyung H. Kim, Sean C. Sleight, Costas D. Maranas, Herbert M. Sauro Metabolic Engineering, doi:10.1016/j.ymben.2012.03.001 (2012)
Nickel (II)-Schiff base complex recognizing domain II of bovine and human serum albumin: Spectroscopic and docking studies Aurkie Ray, Banabithi Koley Seth, Uttam Pal, Samita Basu Spectrochimica Acta Part A: Molecular and Biomolecular Spect, doi:10.1016/j.saa.2012.02.060 (2012)
Modular engineering of a microbially-produced viral capsomere vaccine for influenza Nani Wibowo, Yap P. Chuan, Linda H.L. Lua, Anton P.J. Middelberg Chemical Engineering Science, doi:10.1016/j.ces.2012.04.001 (2012)
Predicting kinase-substrate interactions in the era of proteomics. Focus on “Identifying protein kinase target preferences using mass spectrometry” Ewout J. Hoorn and Marcel E. Meima Am J. Phyiol. Cell Physiol., 10.1152/ajpcell.00232.2012 (2012)
Search and Analysis of Identical Reverse Octapeptides in Unrelated Proteins Konda Mani Saravanan, Samuel Selvaraj Genomics, Proteomics & Bioinformatics, doi://10.1016/j.gpb.2012.11.005 (2012)

Self-consistent treatment of the local dielectric permittivity and electrostatic potential in solution for polarizable macromolecular force fields Sergio A Hassan J. Chem. Phys. , doi://10.1063/1.4742910 (2012)
Effects of Point Substitutions on the Structure of Toxic Alzheimer's β-Amyloid Channels: Atomic Force Microscopy and Molecular Dynamics Simulations Connelly L, Jang H, Arce FT, Ramachandran S, Kagan BL, Nussinov R, Lal R. Biochemistry, doi: 10.1021/bi300257e (2012)
Quantitative Proteomics Identifies Vasopressin-Responsive Nuclear Proteins in Collecting Duct Cells. Laura K. Schenk, Steven J. Bolger, Kelli Luginbuhl, Patricia A. Gonzales, Markus M. Rinschen, Ming-Jiun Yu, Jason D. Hoffert, Trairak Pisitkun and Mark A. Knepper J. Am. Soc. Nephrology, doi: 10.1681/ASN.2011070738 (2012)
Whole-brain, time-locked activation with simple tasks revealed using massive averaging and model-free analysis Javier Gonzalez-Castillo, Ziad S. Saad, Daniel A. Handwerker, Souheil J. Inati, Noah Brenowitz, and Peter A. Bandettini PNAS, doi: 10.1073/pnas.1121049109 (2012)
Comprehensive Research Synopsis and Systematic Meta-Analyses in Parkinson's Disease Genetics: The PDGene Database Lill CM , Roehr JT , McQueen MB , Kavvoura FK , Bagade S , et al. PLoS Genetics, doi:10.1371/journal.pgen.1002548 (2012)
Unraveling the ORE1 Regulon in Arabidopsis thaliana: Molecular and Functional Characterization of Up- and Down-stream Components von Lilian Paola Matallana-Ramírez PhD Thesis, University of Potsdam (2012)
SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome BA Liu, BW Engelmann, K Jablonowski, K Higginbotham, AB Stergachis and PD Nash Cell Communication and Signaling 10:27 (2012)
Optimization and Modeling of Protein Refolding Conditions Bernd Rainer Kurt Anselment PhD Thesis, Institute of Biochemical Engineering of the Technische Universit�t M�nchen (2012)
Cooperative Genome-Wide Analysis Shows Increased Homozygosity in Early Onset Parkinson's Disease Simón-Sánchez J , Kilarski LL , Nalls MA , Martinez M , Schulte C , et al. PLoS One, doi:10.1371/journal.pone.0028787 (2012)
Stochastic Modeling for the Expression of a Gene Regulated by Competing Transcription Factors Hsih-Te Yang, Minoru S. H. Ko PLoS One, doi:10.1371/journal.pone.0032376 (2012)
Marginal analysis of longitudinal count data in long sequences: Methods and applications to a driving study Zhiwei Zhang, Paul S. Albert, and Bruce Simons-Morton Ann.Appl.Stat. 6(1):27-54 (2012)
Theory and simulation of ion conduction in the pentameric GLIC channel Fangqiang Zhu and Gerhard Hummer J. Chem. Theory and Computation, doi: 10.1021/ct2009279 (2012)

A Meta-Analysis and Genome-Wide Association Study of Platelet Count and Mean Platelet Volume in African Americans Qayyum R , Snively BM , Ziv E , Nalls MA , Liu Y , et al. PLoS Genetics, doi:10.1371/journal.pgen.1002491 (2012)
Distinct Regulatory Mechanisms and Functions for p53-Activated and p53-Repressed DNA Damage Response Genes in Embryonic Stem Cells Mangmang Li, Yunlong He, Wendy Dubois, Xiaolin Wu, Jianxin Shi, Jing Huang Molecular Cell, doi:10.1016/j.molcel.2012.01.020 (2012)
Modeling fecundity in the presence of a sterile fraction using a semi-parametric transformation model for grouped survival data Alexander McLain, Rajeshwari Sundaram, Germaine Buck Louis Stat. Meth. in Med. Res. , doi: 10.1177/0962280212438646 (2012)
Pair diffusion, hydrodynamic interactions, and available volume in dense fluids Jeetain Mittal, Gerhard Hummer arXiv preprint, arXiv:1202.6039 (2012)
Sensitive mapping of recombination hotspots using sequencing-based detection of ssDNA Pavel P Khil, Fatima Smagulova, Kevin M Brick, R. Daniel Camerini-Otero and Galina V Petukhova Genome Res., doi:10.1101/gr.130583.111 (2012)
A Bayesian approach to mixture cure models with spatial frailties for population-based cancer relative survival data Binbing Yu, Ram C. Tiwari Canadian Journal of Statistics, doi: 10.1002/cjs.10135 (2012)

Using DNAWorks in Designing Oligonucleotides for PCR-Based Gene Synthesis. David Hoover Methods in Molecular Biology 852(3):215-223 (2012)
Comparison of Common Homology Modeling Algorithms: Application of User-Defined Alignments. Michael A. Dolan, James W. Noah and Darrell Hurt Methods in Molecular Biology 857:399-414 (2012)
The elusive phosphotyrosine: pinning down a rare species. Focus on “Large-scale phosphotyrosine proteomic profiling of rat renal collecting duct epithelium reveals predominance of proteins involved in cell polarity determination Carolyn M. Ecelbarger Am J Physiol Cell Physiol January 302:C16-C17 (2012)
Computational separation of conformational heterogeneity using cryo-electron tomography and 3D sub-volume averaging Gabriel A. Frank, Alberto Bartesaghi, Oleg Kuybeda, Mario J. Borgnia, Tommi A. White, Guillermo Sapiro, Sriram Subramaniam J. Struct. Biol. , doi:/10.1016/j.jsb.2012.01.004 (2012)
A Joint Mixed Effects Dispersion Model for Menstrual Cycle Length and Time-to-Pregnancy Alexander C. McLain, Kirsten J. Lum, Rajeshwari Sundaram Biometrics, doi: 10.1111/j.1541-0420.2011.01711.x (2012)
PDB Ligand Conformational Energies Calculated Quantum-Mechanically Markus Sitzmann, Iwona Wedlich, Igor V Filippov, Chenzhong Liao, Megan L. Peach, Wolf-Dietrich Ihlenfeldt, Rajeshri G Karki, Yulia V Borodina, Raul E Cachau, and Marc C Nicklaus J. Chem. Inf. Model. , doi: 10.1021/ci200595n (2012)

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke The International Stroke Genetics Consortium (ISGC), the Wellcome Trust Case Control Consortium et al. Nature Genetics, doi:10.1038/ng.1081 (2012)
A simple recipe for the non-expert bioinformaticist for building experimentally-testable hypotheses for proteins with no known homologs Alexander Zawaira and Youtaro Shibayama J. Struct. Funct. Genomics, doi://10.1007/s10969-012-9141-7 (2012)
DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes Ofir Hakim, Wolfgang Resch, Arito Yamane, Isaac Klein, Kyong-Rim Kieffer-Kwon, Mila Jankovic, Thiago Oliveira, Anne Bothmer, Ty C. Voss, Camilo Ansarah-Sobrinho, Ewy Mathe, Genqing Liang, Jesse Cobell, Hirotaka Nakahashi, Davide F. Robbiani, Andre Nussenzweig, Gordon L. Hager, Michel C. Nussenzweig & Rafael Casellas Nature, doi:10.1038/nature10909 (2012)
Bubblegrams Reveal the Inner Body of Bacteriophage φKZ Weimin Wu, Julie A. Thomas, Naiqian Cheng, Lindsay W. Black, Alasdair C. Steven Science 335 (6065):182 (2012)
Integrated cross-species transcriptional network analysis of metastatic susceptibility Ying Hu, Gang Wu, Michael Rusch, Luanne Lukes, Kenneth H. Buetow, Jinghui Zhang, and Kent W. Hunter PNAS, doi: 10.1073/pnas.1117872109 (2012)
All-D-Enantiomer of β-Amyloid Peptide Forms Ion Channels in Lipid Bilayers Ricardo Capone, Hyunbum Jang, Samuel A Kotler, Laura S Connelly, Fernando Teran Arce, Srinivasan Ramachandran, Bruce L. Kagan, Ruth Nussinov, and Ratnesh Lal J. Chem. Theory and Computation, doi: 10.1021/ct200885r (2012)
Inositol phosphate-induced stabilization of inositol 1, 3, 4, 5, 6-pentakisphosphate 2-kinase and its role in substrate specificity Varin Gosein, Ting-Fung Leung, Oren Krajden, Gregory J. Miller Protein Science, doi: 10.1002/pro.2049 (2012)
Probing Structural Features of Alzheimer's β-Amyloid Pores in Bilayers Using Site-Specific Amino Acid Substitutions Ricardo Capone, Hyunbum Jang, Samuel A Kotler, Bruce L. Kagan, Ruth Nussinov, and Ratnesh Lal J. Phys. Chem. B, doi: 10.1021/bi2017427 (2012)
Atomic Force Microscopy and MD Simulations Reveal Pore-Like Structures of All-D-Enantiomer of Alzheimer's β-Amyloid Peptide: Relevance to the Ion Channel Laura S Connelly, Fernando Teran Arce, Hyunbum Jang, Ricardo Capone, Samuel A Kotler, Srinivasan Ramachandran, Bruce L. Kagan, Ruth Nussinov, and Ratnesh Lal J. Phys. Chem. B, doi: 10.1021/jp2108126 (2012)

2011 (131 papers)

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies International Parkinson Disease Genomics Consortium Lancet, doi: 10.1016/S0140-6736(10)62345-8 (2011)
Comparing statistical methods for removing seasonal variation from vitamin D measurements in case-control studies Hong Zhang, Jiyoung Ahn, and Kai Yu Statistics and its Interface 3:85-93 (2011)
Antimicrobial Protegrin-1 Forms Amyloid-Like Fibrils with Rapid Kinetics Suggesting a Functional Link Hyunbum Jang, Fernando Teran Arce, Mirela Mustata, Srinivasan Ramachandran, Ricardo Capone, Ruth Nussinov, Ratnesh Lal Biophys. J., doi: 10.1016/j.bpj.2011.01.072 (2011)
Quantifying Protein-Protein Interactions Within Noncovalent Complexes Using Electrospray Ionization Mass Spectrometry Elisabetta Boeri Erba, Konstantin Barylyuk, Yang Yang, and Renato Zenobi Anal. Chem. 83(24):9251-9259 (2011)
Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes Klein IA, Resch W, Jankovic M, Oliveira T, Yamane A, Nakahashi H, Di Virgilio M, Bothmer A, Nussenzweig A, Robbiani DF, Casellas R, Nussenzweig MC. Cell 147(1):95-106 (2011)
Recombination mapping using Boolean logic and high-density SNP genotyping for exome sequence filtering Thomas C. Markello, Ted Han, Hannah Carlson-Donohoe, Chidi Ahaghotu, Ursula Harper, MaryPat Jones, Settara Chandrasekharappa, Yair Anikster, David R. Adams, NISC Comparative Sequencing Program, William A. Gahl, Cornelius F. Boerkoel Mol. Genetics & Metabolism, doi:10.1016/j.ymgme.2011.12.014 (2011)
Independent component analysis of resting brain activity reveals transient modulation of local cortical processing by transcranial direct current stimulation. Venkatakrishnan A, Contreras-Vidal JL, Sandrini M, Cohen LG. Conf Proc IEEE Eng Med Biol Soc. Aug:8102-5 (2011)
The Anatomical Distance of Functional Connections Predicts Brain Network Topology in Health and Schizophrenia Aaron F. Alexander-Bloch, Petra E. Vértes, Reva Stidd, François Lalonde, Liv Clasen, Judith Rapoport, Jay Giedd, Edward T. Bullmore and Nitin Gogtay Cerebral Cortex, doi:10.1093/cercor/bhr388 (2011)
Parietofrontal integrity determines neural modulation associated with grasping imagery after stroke Ethan R. Buch, Amirali Modir Shanechi, Alissa D. Fourkas, Cornelia Weber, Niels Birbaumer and Leonardo G. Cohen Brain, doi:10.1093/brain/awr331 (2011)

Analysis of Biological Features Associated with Meiotic Recombination Hot and Cold Spots in Saccharomyces cerevisiae Loren Hansen, Nak-Kyeong Kim, Leonardo Mariño-Ramírez, David Landsman PLoS One, doi:10.1371/journal.pone.0029711 (2011)
Tryptic y++ Fragment Ion Distributions Are Guided by Coulombic Repulsion Karl K. Irikura, John K. Merle and Yamil Sim´n-Manso J. Am. Soc. Mass Spec., doi:10.1007/s13361-011-0293-7 (2011)
Structural models of TREK channels and their gating mechanism Adina L Milac, Andriy Anishkin, Sarosh N Fatakia, Carson C Chow, Sergei Sukharev, and H Robert Guy Channels, doi: 10.4161/chan.5.1.13905 (2011)
Expression, purification and characterization of recombinant human serine proteinase inhibitor Kazal-type 6 (SPINK6) in Pichia pastoris Hairong Lu, Jinjiang Huang, Guodong Li, Kuikui Ge, Hongyu Wu, Qingshan Huang Protein Expression and Purification, doi:10.1016/j.pep.2011.12.004 (2011)
Overproduction of recombinant proteins in plants Erin Egelkrout, Vidya Rajan, John A. Howard Plant Science, doi:10.1016/j.plantsci.2011.12.005 (2011)
Condensin dysfunction in human cells induces nonrandom chromosomal breaks in anaphase, with distinct patterns for both unique and repeated genomic regions Alexander Samoshkin, Stanimir Dulev, Dmitry Loukinov, Jeffrey A. Rosenfeld and Alexander V. Strunnikov Chromosoma Biology of the Nucleus, doi: 10.1007/s00412-011-0353-6 (2011)

Effects of pH on proteins: Predictions for ensemble and single molecule pulling experiments Edward P O'Brien , Bernard R. Brooks , and Devarajan Thirumalai JACS, doi: 10.1021/ja206557y (2011)
Inherited Variation at Chromosome 12p13. 33, Including RAD52, Influences the Risk of Squamous Cell Lung Carcinoma Jianxin Shi, Nilanjan Chatterjee, Melissa Rotunno, Yufei Wang, Angela C. Pesatori, Dario Consonni, Peng Li, William Wheeler, Peter Broderick, Marc Henrion, Timothy Eisen, Zhaoming Wang, Wei Chen, Qiong Dong, Demetrius Albanes, Michael Thun, Margaret R. Spitz, Pier Alberto Bertazzi, Neil E. Caporaso, Stephen J. Chanock, Christopher I. Amos, Richard S. Houlston and Maria Teresa Landi Cancer Discovery, doi: 10.1158/2159-8290.CD-11-024 (2011)
Causal Inference on Quantiles with an Obstetric Application Zhiwei Zhang, Zhen Chen, James F. Troendle, and Jun Zhang Biometrics, doi: 10.1111/j.1541-0420.2011.01712.x (2011)
Does feature selection improve classification accuracy? Impact of sample size and feature selection on classification using anatomical magnetic resonance images Carlton Chu, Ai-Ling Hsu, Kun-Hsien Chou, Peter Bandettini, Ching-Po Lin, , and the Alzheimer's Disease Neuroimaging Initiative NeuroImage, doi:10.1016/j.neuroimage.2011.11.066 (2011)
Structural basis of anthrax edema factor neutralization by a neutralizing antibody Michelle Makiya, Michael Dolan, Liane Agulto, Robert Purcell, Zhaochun Chen Biochem. Biophys. Res. Comm., doi:10.1016/j.bbrc.2011.11.108 (2011)
High-level expression and characterization of a highly thermostable chitosanase from Aspergillus fumigatus in Pichia pastoris Xiaomei Chen, Chao Zhai, Lixin Kang, Chunhua Li, Hong Yan, Yuling Zhou, Xiaolan Yu and Lixin Ma Biotech. Letters, doi: 10.1007/s10529-011-0816-0 (2011)

Determination of Molecular Structures of HIV Envelope Glycoproteins using Cryo-Electron Tomography and Automated Sub-tomogram Averaging. Joel R. Meyerson, Tommi A. White et al J. Visualized Experiments, doi: 10.3791/2770 (2011)
Interaction of Merocyanine 540 with Serum Albumins: Photophysical and Binding Studies Mousumi Banerjee, Uttam Pal, Arijita Subudhhi, Abhijit Chakrabarti, Samita Basu J. Photochemistry and Photobiology B, doi:10.1016/j.jphotobiol.2011.12.005 (2011)
Gene Expression Databases for Kidney Epithelial Cells Jennifer C. Huling, Trairak Pisitkun, Jae H. Song, Ming-Jiun Yu, Jason D. Hoffert, and Mark A. Knepper Am. J. Physiol. - Renal Physiol., doi: 10.?1152/?ajprenal.?00457.?2011 doi: 10.?1152/?ajprenal.?00457.?2011 (2011)
Dynamics of the G protein-coupled vasopressin V2 receptor signaling network revealed by quantitative phosphoproteomics Jason D. Hoffert, Trairak Pisitkun, Fahad Saeed, Jae V. Song, Chung-Lin Chou and Mark A. Knepper Mol. Cell Proteomics, doi: 10.1074/mcp.M111.014613 (2011)
Standard reactions for comparative rate studies: Experiments on the dehydrochlorination reactions of 2-chloropropane, chlorocyclopentane, and chlorocyclohexane Iftikhar A. Awan, Donald R. Burgess Jr., Wing Tsang, Jeffrey A. Manion Int. J. Chem. Kinetics, doi: 10.1002/kin.20566 (2011)
Convergence and error estimation in free energy calculations using the weighted histogram analysis method Fangqiang Zhu, Gerhard Hummer J. Comp. Chem. , doi: 10.1002/jcc.21989 (2011)

The discovery of population differences in network community structure: New methods and applications to brain functional networks in schizophrenia Aaron Alexander-Bloch, Renaud Lambiotte, Ben Roberts, Jay Giedd, Nitin Gogtay, Ed Bullmore NeuroImage, doi:10.1016/j.neuroimage.2011.11.035 (2011)
A linear mixed model for predicting a binary event from longitudinal data under random effects misspecification Paul S. Albert Stat. Med., doi: 10.1002/sim.4405 (2011)
Antimicrobial Properties of Amyloid Peptides Bruce Kagan , Hyunbum Jang , Ricardo Capone , Fernando Teran Arce , Srinivasan Ramachandran , Ratnesh Lal , and Ruth Nussinov Molecular Pharmaceutics, doi: 10.1021/mp200419b (2011)
Extensive chromatin remodelling and establishment of transcription factor 'hotspots' during early adipogenesis Rasmus Siersbæk, Ronni Nielsen, Sam John, Myong-Hee Sung, Songjoon Baek, Anne Loft, Gordon L Hager and Susanne Mandrup Embo J. , doi:10.1038/emboj.2011.65 (2011)
Material Properties of Matrix Lipids Determine Conformation and Intermolecular Reactivity of a Diacetylenic Phosphatidylcholine in the Lipid Bilayer Anu Puri , Hyunbum Jang , Amichai Yavlovich , Athar M Masood , Timothy D. Veenstra , Carlos Luna , Helim Aranda-Espinoza , Ruth Nussinov , and Robert Blumenthal Langmuir, doi: 10.1021/la203453x (2011)
Expressão e caracterização de fragmentos de anticorpos recominanes Anti-CD3 humano em Pichia pastoris Sousa, Victor Edgard Tavares Master's thesis, University of Brasilia (2011)

Genome-Wide Association Analysis of Ischemic Stroke in Young Adults Yu-Ching Cheng, Jeffrey R. O'Connel et al Genes | Genomes | Genetics, doi: 10.1534/g3.111.001164 (2011)
Three-Dimensional Structures of Soluble CD4-Bound States of Trimeric Simian Immunodeficiency Virus Envelope Glycoproteins Determined by Using Cryo-Electron Tomography Tommi A. White, Alberto Bartesaghi, Mario J. Borgnia, M. Jason V. de la Cruz, Rachna Nandwani, James A. Hoxie, Julian W. Bess, Jeffrey D. Lifson, Jacqueline L. S. Milne and Sriram Subramaniam J. Virol., doi: 10.1128/?JVI.05297-11 (2011)
Dehydratase Mediated 1-Propanol Production in Metabolically Engineered Escherichia coli. Rachit Jain, Yajun Yan Microbial Cell Factories, doi:10.1186/1475-2859-10-97 (2011)
The Histone Database: an integrated resource for histones and histone fold-containing proteins Leonardo Mariño-Ramírez, Kevin M. Levine, Mario Morales, Suiyuan Zhang, R. Travis Moreland, Andreas D. Baxevanis and David Landsman J. Biol. Databases and Curation, doi: 10.1093/database/bar048 (2011)
Water-Exclusion Effects and Liquid-Structure Forces in Implicit Solvation Sergio A Hassan and Peter J Steinbach J. Phys. Chem. B, doi: 10.1021/jp208184e (2011)
Impact of surface roughness on diffusion of confined fluids William P. Krekelberg, Vincent K. Shen, Jeffrey R. Errington, and Thomas M. Truskett J. Chem. Phys. , doi:10.1063/1.3651478 (2011)
An electrostatic switch controls palmitoylation of the large conductance voltage-and calcium-activated potassium (BK) channel Owen Jeffries, Lijun Tian, Heather McClafferty & Michael J. Shipston. J. Biol. Chem. , doi: 10.1074/jbc.M111.224840 (2011)
Energetics of direct and water-mediated proton-coupled electron transfer. Ville R. I. Kaila and Gerhard Hummer JACS, doi: 10.1021/ja2082262 (2011)
Resting and Active States of the ERK2: HePTP Complex Dana M. Francis, Bartosz Rózycki, Antoni Tortajada, Gerhard Hummer, Wolfgang Peti, and Rebecca Page JACS, doi: 10.1021/ja2075136 (2011)
Dynamic water networks in cytochrome cbb3 oxidase Vivek Sharma, Mårten Wikströma, Ville R.I. Kaila Biochim. et Biophys. Acta, doi:10.1016/j.bbabio.2011.09.010 (2011)
Identification, Replication, and Fine-Mapping of Loci Associated with Adult Height in Individuals of African Ancestry N'Diaye A, Chen GK et al. PLoS Genetics, doi:10.1371/journal.pgen.1002298 (2011)
Synthesis and bio-evaluation of human macrophage migration inhibitory factor inhibitor to develop anti-inflammatory agent Athar Alama, Chinmay Pala, Manish Goyala, Milan Kumar Kundub, Rahul Kumara, Mohd Shameel Iqbala, Sumanta Deya, Samik Bindua, Souvik Sarkara, Uttam Palc, Nakul C. Maitic, Susanta Adhikarid, Uday Bandyopadhyay Bioorganic and Medicinal Chemistry, doi:10.1016/j.bmc.2011.10.056 (2011)

Investigation of Anatomical Thalamo-Cortical Connectivity and fMRI Activation in Schizophrenia Stefano Marenco, Jason L Stein, Antonina A Savostyanova, Fabio Sambataro, Hao-Yang Tan, Aaron L Goldman, Beth A Verchinski, Alan S Barnett, Dwight Dickinson, José A Apud, Joseph H Callicott, Andreas Meyer-Lindenberg and Daniel R Weinberger Neuropsychopharmacology, doi: 10.1038/npp.2011.215 (2011)
NHLBI-AbDesigner: An online tool for design of peptide-directed antibodies Trairak Pisitkun, Jason D. Hoffert, Fahad Saeed, and Mark A. Knepper Am. J. Cell. Physiol. , doi: 10.1152/ajpcell.00325.201 (2011)
A coarse-grained model for PEGylated lipids: the effect of PEGylation on size and shape of self-assembled structures Hwankyu Lee, Richard W. Pastor J. Phys. Chem. B, doi: 10.1021/jp2020148 (2011)
Oncogenically active MYD88 mutations in human lymphoma V.N. Ngo, R.M. Young, R. Schmitz et al Nature, doi:10.1038/nature09671 (2011)
Overexpression of synthesized cephalosporin C acylase containing mutations in the substrate transport tunnel Ying Wang, Huimin Yu, Wensi Song, Ming An, Jing Zhang, Hui Luo, Zhongyao Shen J. Biosci. Bioeng., doi:10.1016/j.jbiosc.2011.08.027 (2011)
Capsomer Vaccines Protect Mice from Vaginal Challenge with Human Papillomavirus Wai-Hong Wu, Elizabeth Gersch, Kihyuck Kwak, Subhashini Jagu, Balasubramanyam Karanam, Warner K. Huh, Robert L. Garcea, Richard B. S. Roden PLoS One, doi:10.1371/journal.pone.0027141 (2011)

N-Protonated Isomers as Gateways to Peptide Ion Fragmentation Fredrik Haeffner, John K. Merle and Karl K. Irikura J. Am. Soc. Mass Spec., doi: 10.1007/s13361-011-0241-6 (2011)
PubChem3D: Biologically relevant 3-D similarity Sunghwan Kim , Evan E Bolton and Stephen H Bryant J. Cheminform., doi:10.1186/1758-2946-3-26 (2011)
Genomic Risk Profiling of Ischemic Stroke: Results of an International Genome-Wide Association Meta-Analysis James F. Meschia, Andrew Singleton, Michael A. Nalls, Stephen S. Rich, Pankaj Sharma, Luigi Ferrucci, Mar Matarin, Dena G. Hernandez, Kerra Pearce, Thomas G. Brott, Robert D. Brown Jr., John Hardy, Bradford B. Worrall PLoS One, doi:10.1371/journal.pone.0023161 (2011)
Large-Scale Phosphotyrosine Proteomic Profiling of Rat Renal Collecting Duct Epithelium Reveals Predominance of Proteins Involved in Cell Polarity Determination Boyang Zhao, Mark A. Knepper, Chung-Lin Chou, and Trairak Pisitkun Cell Physiol. , doi: 10.?1152/ajpcell.00300.2011 (2011)
Logistic regression analysis of biomarker data subject to pooling and dichotomization Z. Zhang, A. Liu, R.H., Lyles, B. Mukherjee Statistics in Medicine, doi: 10.1002/sim.4367 (2011)
Generalized degrees of freedom and adaptive model selection in linear mixed-effects models Bo Zhang, Xiaotong Shen, Sunni L. Mumford Comp. Stats & Data Anal., doi:10.1016/j.csda.2011.09.001 (2011)

Flexible cullins in cullin-ring E3 ligases allosterically regulate ubiquitination Jin Liu and Ruth Nussinov J. Biol. Chem. , doi: 10.1074/jbc.M111.277236 (2011)
Application of a yeast two-hybrid based screening system in the identification of amyloid-beta aggregation inhibitors in pharmaceutical plants Li-Wei Wang, Yan-Fang Yang, Ying-Tao Zhang J. Chinese Pharm. Sciences 20(5):510-517 (2011)
Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo Shehab A Ismail, Yong-Xiang Chen, Alexandra Rusinova, Anchal Chandra, Martin Bierbaum, Lothar Gremer, Gemma Triola, Herbert Waldmann, Philippe I H Bastiaens & Alfred Wittinghofer Nature Chem. Bio. , doi:10.1038/nchembio.686 (2011)
In silico implementation of synthetic gene networks. Mario Andrea Marchisio Methods in Mol. Bio. , doi: 10.1007/978-1-61779-412-4_1 (2011)
Selective cell-surface labeling of the molecular motor protein prestin Ryan M. McGuire, Jonathan J. Silberg, Fred A. Pereira, c, Robert M. Raphael Biochem. Biophys. Res. Comm., doi://10.1016/j.bbrc.2011.05.121 (2011)
The Core of Ure2p Prion Fibrils Is Formed by the N-Terminal Segment in a Parallel Cross-? Structure: Evidence from Solid-State NMR Dmitry S. Kryndushkin, Reed B. Wickner, Robert Tycko J. Mol. Biol. , doi://10.1016/j.jmb.2011.03.067 (2011)
Latent class models for joint analysis of disease prevalence and high-dimensional semicontinuous biomarker data Bo Zhang, Zhen Chen and Paul S. Albert Biostatistics, doi: 10.1093/biostatistics/kxr024 (2011)
White Matter Microstructural Correlates of Superior Long-term Skill Gained Implicitly under Randomized Practice Sunbin Song, Nikhil Sharma, Ethan R. Buch and Leonardo G. Cohen Cerebral Cortex, doi: 10.1093/cercor/bhr247 (2011)
Genetic Association for Renal Traits among Participants of African Ancestry Reveals New Loci for Renal Function C-T Liu, MK Garnaas et al. PLoS Genetics, doi:10.1371/journal.pgen.1002264 (2011)
A Network-Based Approach to Prioritize Results from Genome-Wide Association Studies N. Akula, A. Baranova, D Seto, J Solka, MA Nalls, A Singleton, L Ferrucci, T Tanaka, S Bandinelli, YS Cho, YJ Kim, J-Y Lee, B-G Han, Bipolar Disorder Genome Study (BiGS) Consortium, The Wellcome Trust Case-Control Consortium, FJ McMahon PLoS One, doi:10.1371/journal.pone.0024220 (2011)
Conditional Allele Mouse Planner (CAMP): software to facilitate the planning and design of breeding strategies involving mice with conditional alleles Jason D. Hoffert, Trairak Pisitkun, R. Lance Miller. Transgenic Research, doi: 10.1007/s11248-011-9545-3 (2011)
Tackling Force-Field Bias in Protein Folding Simulations: Folding of Villin HP35 and Pin WW Domains in Explicit Water Jeetain MIttal and Robert B. Best Biophys. J. , doi: 10.1016/j.bpj.2010.05.005 (2011)

Rbx1 Flexible Linker Facilitates Cullin-RING Ligase Function Before Neddylation and After Deneddylation Jin Liu and Ruth Nussinov Biophys. J. , doi: 10.1016/j.bpj.2010.05.021 (2011)
Polymorphic Triple β-Sheet Structures Contribute to Amide Hydrogen/Deuterium (H/D) Exchange Protection in the Alzheimer Amyloid β42 Peptide Buyong Ma and Ruth Nussinov J. Biol. Chem. , doi: 10.1074/jbc.M111.241141 (2011)
Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials Holmes MV, Newcombe, P, Hubacek JA et a. The Lancet, doi:10.1016/S0140-6736 (2011)
Genome-wide Association Study for Serum Urate Concentrations and Gout among African Americans Identifies Genomic Risk Loci and a Novel URAT1 Loss-of-Function Allele Tin, A, Woordward OM et al. Hum. Mol. Genet., doi: 10.1093/hmg/ddr307 (2011)
Structural variants of IFNα preferentially promote antiviral functions Nancy Vázquez, Hana Schmeisser, Michael A. Dolan, Joseph Bekisz, Kathryn C. Zoon and Sharon M. Wahl Blood, doi:10.1182/blood-2010-12-325027 (2011)
Enhanced translation by Nucleolin via G-rich elements in coding and non-coding regions of target mRNAs Kotb Abdelmohsen, Kumiko Tominaga, Eun Kyung Lee, Subramanya Srikantan, Min-Ju Kang, Mihee M. Kim, Roza Selimyan, Jennifer L. Martindale, Xiaoling Yang, France Carrier, Ming Zhan, Kevin G. Becker and Myriam Gorospe Nucleic Acids Research, doi: 10.1093/nar/gkr488 (2011)

A Two-Stage Meta-Analysis Identifies Several New Loci for Parkinson's Disease. International Parkinson's Disease Genomics Consortium (IPDGC) and Wellcome Trust Case Control Consortium 2 (WTCCC2) PLoS Genetics, doi: 10.1371/journal.pgen.1002142 (2011)
A general Monte Carlo/simulated annealing algorithm for resonance assignment in NMR of uniformly labeled biopolymers Kan-Nian Hu, Wei Qiang and Robert Tycko J. Biomol. NMR, doi: 10.1007/s10858-011-9517-1 (2011)
Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures Audray Harris, Mario J. Borgnia, Dan Shi, Alberto Bartesaghi, Haifeng He, Robert Pejchal, Yun (Kenneth) Kang, Rafael Depetris, Andre J. Marozsan, Rogier W. Sanders, Per Johan Klasse, Jacqueline L. S. Milne, Ian A. Wilson, William C. Olson, John P. Moore, and Sriram Subramaniam PNAS, doi: 10.1073/pnas.1101414108 (2011)
Genome-Wide Association Study of White Blood Cell Count in 16,388 African Americans: the Continental Origins and Genetic Epidemiology Network (COGENT) Reiner AP, Lettre G, Nalls MA, Ganesh SK, Mathias R, et al. PLoS Genetics, doi:10.1371/journal.pgen.1002108 (2011)
Multiple Loci Are Associated with White Blood Cell Phenotypes Nalls MA, Couper DJ, Tanaka T, van Rooij FJA, Chen M-H, et al. PLoS Genetics, doi:10.1371/journal.pgen.1002113 (2011)
Phage display of tissue inhibitor of metalloproteinases-2 (TIMP-2): Identification of selective inhibitors of collagenase-1 (MMP-1) Harinath Bahudhanapati, Yingnan Zhang, Sachdev S. Sidhu and Keith Brew J. Biol. Chem. , doi: 10.1074/jbc.M111.253328 (2011)

Energetics and dynamics of proton transfer reactions along short water wires Ville R. I. Kaila and Gerhard Hummer Phys. Chem. Chem. Phys. , doi:10.1039/C1CP21112A (2011)
A survival analysis approach to modeling human fecundity Rajeshwari Sundaram, Alexander C. Mclain and Germaine M. Buck Louis Biostatistics, doi: 10.1093/biostatistics/kxr015 doi: 10.1093/biostatistics/kxr015 doi: 10.1093/biostatistics/kxr01 (2011)
Simulated Self-Assembly of the HIV-1 Capsid: Protein Shape and Native Contacts Are Sufficient for Two-Dimensional Lattice Formation Bo Chen and Robert Tycko Biophys. J. , doi: 10.1016/j.bpj.2011.05.025 (2011)
PubChem3D: Similar conformers Evan Bolton, Sunghwan Kim and Stephen H Bryant J. Cheminform. , doi: 10.1186/1758-2946-3-13. (2011)
Microscopic events in β-hairpin folding from alternative unfolded ensembles Robert Best & Jeetain Mittal PNAS, doi: 10.1073/pnas.1016685108 (2011)
The Role of Response Elements Organization in Transcription Factor Selectivity: The IFN-β Enhanceosome Example Yongping Pan, Ruth Nussinov PLoS Computational Biology, doi:10.1371/journal.pcbi.1002077 (2011)

Thermodynamics of Boroxine Formation from the Aliphatic Boronic Acid Monomers R-B (OH) 2 (R= H, H3C, H2N, HO, and F): A Computational Investigation Krishna L. Bhat, George D. Markham, Joseph D. Larkin, and Charles W. Bock J. Phys. Chem. A, doi: 10.1021/jp202409m (2011)
Agricultural intensification, priming for persistence and the emergence of Nipah virus: a lethal bat-borne zoonosis Juliet R. C. Pulliam, Jonathan H. Epstein, Jonathan Dushoff, Sohayati A. Rahman, Michel Bunning, Aziz A. Jamaluddin, Alex D. Hyatt, Hume E. Field, Andrew P. Dobson and Peter Daszak, the Henipavirus Ecology Research Group (HERG) Journal of the Royal Society Interface, doi: 10.1098/?rsif.2011.0223 (2011)
Tools for Vaccine Design: Prediction and Validation of Highly Immunogenic and Conserved Class II Epitopes and Development of Epitope-Driven Vaccines Manmohan Singh, Indresh K. Srivastava Anne S. De Groot, Matthew Ardito, Ryan Tassone, Paul Knopf, Leonard Moise, William Martin Development of Vaccines: From Discovery to Clinical Testing, John Wiley & Sons, doi: 10.1002/9781118023648.ch3 (2011)
Improved genetic association tests for an ordinal outcome representing the disease progression process Hong Zhang, Sholom Wacholder, Jing Qin, Allan Hildesheim, Kai Yu Genetic Epidemiology, doi: 10.1002/gepi.20599 (2011)
Roles of the four DNA polymerases of the crenarchaeon Sulfolobus solfataricus and accessory proteins in DNA replication Jeong-Yun Choi, Robert L. Eoff, Matthew G. Pence, Jian Wang, Martha V. Martin, Eun-Jin Kim, Lindsay M. Folkmann and F. Peter Guengerich J. Biol. Chem. , doi: 10.1074/jbc.M111.258038 (2011)
RNAi-independent role for Argonaute2 in CTCF/CP190 chromatin insulator function Moshkovich N, Nisha P, Boyle PJ, Thompson BA, Dale RK, Lei EP Genes Dev., doi: 10.1101/gad.16651211 (2011)

Polymorphism of amyloid β peptide in different environments: implications for membrane insertion and pore formation Fernando Terán Arce, Hyunbum Jang, Srinivasan Ramachandran, Preston B. Landon, Ruth Nussinov and Ratnesh Lal Soft Matter, doi: 10.1039/C1SM05162H (2011)
Catalytic Mechanism of RNA Backbone Cleavage by Ribonuclease H from QM/MM Simulations Edina Rosta , Marcin Nowotny , Wei Yang , and Gerhard Hummer JACS, doi: 10.1021/ja200173a (2011)
Diverse gene reprogramming events occur in the same spatial clusters of distal regulatory elements Ofir Hakim, Myong-Hee Sung, Ty C. Voss, Erik Splinter, Sam John, Peter J. Sabo, Robert E. Thurman, John A. Stamatoyannopoulos, Wouter de Laat, and Gordon L. Hager Genome Research, doi:10.1101/gr.111153.110 (2011)
The association between inflammation-related genes and serum androgen levels in men: The prostate, lung, colorectal, and ovarian study Tamra E. Meyer, Lisa W. Chu, Qizhai Li, Kai Yu, Philip S. Rosenberg, Idan Menashe, Anand P. Chokkalingam, Sabah M. Quraishi, Wen-Yi Huang, Jocelyn M. Weiss, Rudolf Kaaks, Richard B. Hayes, Stephen J. Chanock, Ann W. Hsing The Prostate, doi: 10.1002/pros.21407 (2011)
Cystine knot peptides binding to Alpha IIb Beta 3 integrins and methods of use Cochran, J, Silverman, AP, Kariolis, Mihalis S. US Patent application 20110136740 (2011)
Protein Tertiary Structure Prediction based on main chain angle using a hybrid Bees Colony Optimization Algorithm ZN Mahmood, M. Mahmuddin, M.N. Mahmood International Journal of Modern Physics: Conference Series, DOI: 10.1142/S201019451200520X (2011)
Cloning and overexpression of influenza a H1N1 NS1 protein in escherichia coli Ong, Lih Lih Masters thesis, Universiti Teknologi Malaysia (2011)
Synergistic interactions between repeats in tau protein and Aβ amyloids may be responsible for accelerated aggregation via polymorphic states Yifat Miller, Buyong Ma, and Ruth Nussinov Biochemistry, doi: 10.1021/bi200400u (2011)
Driving Forces Enable High-Titer Anaerobic 1-Butanol Synthesis in Escherichia coli Claire R. Shen, Ethan I. Lan, Yasumasa Dekishima, Antonino Baez, Kwang Myung Cho, and James C. Liao App. Env. Microbiology, doi:10.1128/AEM.03034-10 (2011)
A joint modeling approach to data with informative cluster size: Robustness to the cluster size model Zhen Chen, Bo Zhang, Paul S. Albert Statistics in Medicine, doi: 10.1002/sim.4239 (2011)
On the stability and ranking of predictors from random forest variable importance measures Kristin K Nicodemus Brief. Bioinfo., doi: 10.1093/bib/bbr016 (2011)
Human Insulin production in E.Coli: Gene optimization, Assembly, Cloning and Protein Expression Gamal Abd El-Aziz, Metwali M.Reda, S.H.Abdel-Aziz, EL-Rashdy M. Redwan J. Biotech. Res. 11:37 (2011)

Thermochemistry of imidazolium-based ionic liquids: experiment and first-principles calculations Sergey P. Verevkin, Vladimir N. Emel'yanenko, Dzmitry H. Zaitsau, Andreas Heintz, Chris D. Muzny and Michael Frenkel Phys. Chem. Chem. Phys., doi:10.1039/C0CP00747A (2011)
Intermittent Hypoxia-Induced Sensitization of Central Chemoreceptors Contributes to Sympathetic Nerve Activity during Late Expiration in Rats Yaroslav I. Molkov, Daniel B Zoccal, Davi J.A. Moraes, Julian F.R. Paton, Benedito H. Machado, and Ilya A Rybak J. Neurophysiol., doi: 10.?1152/jn.00070.2011 (2011)
Exploring the energy landscape of a molecular engineered analog of a tumor-homing peptide Guillem Revilla-López, Juan Torras, Ruth Nussinov, Carlos Alemán and David Zanuy Physical Chemistry Chemical Physics, doi: 10.1039/C0CP02572K (2011)
PubChem3D: Diversity of shape Evan Bolton, Sunghwan Kim, and Stephen Bryant J. Cheminform. , doi: 10.1186/1758-2946-3-9 (2011)
Crystal structure of basic 7S globulin, a xyloglucan-specific endo-β-1, 4-glucanase inhibitor protein-like protein from soybean lacking inhibitory activity against endo-β-glucanase Takuya Yoshizawa, Toshiyuki Shimizu, Mayuki Yamabe, Misako Taichi, Yuji Nishiuchi, Naoki Shichijo, Satoru Unzai, Hisashi Hirano, Mamoru Sato, Hiroshi Hashimoto FEBS Journal, doi: 10.1111/j.1742-4658.2011.08111.x (2011)
Conformational Relaxation and Water Penetration Coupled to Ionization of Internal Groups in Proteins Ana Damjanovic, Bernard R. Brooks, and Bertrand García-Moreno E J. Phys. Chem. , published online 23 Mar (2011)

Efficient Adaptively Weighted Analysis of Secondary Phenotypes in Case-Control Genome-Wide Association Studies Huilin Li and Mitchell Gail Human Heredity, DOI: 10.1159/000338943 (2011)
Structural basis of p38α regulation by hematopoietic tyrosine phosphatase Dana M Francis, Bartosz Rózycki, Dorothy Koveal, Gerhard Hummer, Rebecca Page & Wolfgang Peti Nature Chem. Bio. , doi:10.1038/nchembio.707 (2011)
Microscopic mechanism of nanocrystal formation from solution by cluster aggregation and coalescence Sergio A. Hassan J. Chem. Phys. 134:114508 (2011)
PubChem3D: a new resource for scientists Evan E Bolton, Jie Chen, Sunghwan Kim, Lianyi Han, Siqian He, Wenyao Shi, Vahan Simonyan, Yan Sun, Paul A Thiessen and Jiyao Wang, et al. J. Cheminform. 3:32 (2011)
Water Transport through Nanotubes with Varying Interaction Strength between Tube Wall and Water Matthew Melillo, Fangqiang Zhu, Mark A. Snyder, and Jeetain Mittal J. Phys. Chem. Letters (2011)
Large-scale Exploration of Gene-Gene Interactions in Prostate Cancer Using a Multistage Genome-wide Association Study Julia Ciampa, Meredith Yeager, Laufey Amundadottir, Kevin Jacobs, Peter Kraft, Charles Chung, Sholom Wacholder, Kai Yu, William Wheeler, Michael J Thun, W Ryan Divers, Susan Gapstur, Demetrius Albanes, Jarmo Virtamo, Stephanie Weinstein, Edward Giovannucci, Walter C Willet, Geraldine Cancel-Tassin, Olivier Cussenot, Antoine Valeri, David Hunter, Robert Hoover, Gilles Thomas, Stephen Chanock, and Nilanjan Chatterjee Cancer Res., doi: 10.1158/0008-5472.CAN-10-2646 (2011)

PubChem3D: Conformer generation. Evan E Bolton, Sunghwan Kim, and Stephen H Bryant J. Cheminform., doi: 10.1186/1758-2946-3-4 (2011)
Molecular-Level Examination of Cu2+ Binding Structure for Amyloid Fibrils of 40-Residue Alzheimer's β by Solid-State NMR Spectroscopy Sudhakar Parthasarathy, Fei Long, Yifat Miller, Yiling Xiao, Dan McElheny, Kent Thurber, Buyong Ma, Ruth Nussinov, and Yoshitaka Ishii JACS, published online 22 Feb (2011)
Symmetry-Based Self-Assembled Nanotubes Constructed Using Native Protein Structures: The Key Role of Flexible Linkers Buch, Idit; Tsai, Chung-Jung; J. Wolfson, Haim; Nussinov, Ruth Protein & Peptide Letters 18(4):362-372 (2011)
Genome-Wide Association Studies of the PR Interval in African Americans JG Smith, JW. Magnani, C Palmer, YA Meng, EZ Soliman, SK Musani, KF Kerr, RB Schnabel, SA Lubitz, N Sotoodehnia, S Redline, A Pfeufer, M Müller, DS Evans, MA Nalls, Y Liu, AB Newman, AB Zonderman, MK Evans, R Deo, PT Ellinor, DN Paltoo, C Newton-Cheh, E J Benjamin, R Mehra, A Alonso, SR Heckbert, ER Fox, Candidate-gene Association Resource (CARe) Consortium PLoS Genetics, doi:10.1371/journal.pgen.1001304 (2011)
Modelling batched Gaussian longitudinal weight data in mice subject to informative dropout Paul S. Albert, Joanna H Shih Stat. Meth. in Med. Res., doi: 10.1177/0962280210397886 (2011)
The Unique Alzheimer's β-Amyloid Triangular Fibril Has a Cavity along the Fibril Axis under Physiological Conditions Yifat Miller, Buyong Ma, and Ruth Nussinov J. Am. Chem. Soc., doi: 10.1021/ja1100273 (2011)

Novel HIV-1 protease inhibitors (PIs) containing a bicyclic P2 functional moiety, tetrahydropyrano-tetrahydrofuran, that are potent against multi-PI-resistant HIV-1 variants Kazuhiko Ide, Manabu Aoki, Masayuki Amano, Yasuhiro Koh, Ravikiran S. Yedidi, Debananda Das, Sofiya Leschenko, Bruno Chapsal, Arun K. Ghosh, and Hiroaki Mitsuya Antimicrob Agents Chemother., doi:10.1128/AAC.01540-10 (2011)
Binding of a C-end rule peptide to neuropilin-1 receptor: A molecular modeling approach Nurit Haspel , David Zanuy , Ruth Nussinov , Tambet Teesalu , Erkki Ruoslahti , and Carlos Aleman Biochemistry, doi: 10.1021/bi101662j (2011)
SAXS Ensemble Refinement of ESCRT-III CHMP3 Conformational Transitions Bartosz Rózycki, Young C. Kim and Gerhard Hummer Structure, doi:10.1016/j.str.2010.10.006 (2011)
Distinct DNA methylation changes highly correlated with chronological age in the human brain Dena G Hernandez, Michael A Nalls, J Raphael Gibbs, Sampath Arepalli, Marcel van der Brug, Sean Chong, Matthew Moore, Dan L Longo, Mark Cookson, Bryan J Traynor and Andrew Singleton Human Molecular Genetics, published online 7 Jan (2011)
An Audit Strategy for Progression-Free Survival Lori E. Dodd, Edward L. Korn, Boris Freidlin, Robert Gray, Suman Bhattacharya Biometrics, doi: 10.1111/j.1541-0420.2010.01539.x (2011)
Atomistic modeling of peptides bound to a chemically active surface: conformational implications David Curcó, Guillem Revilla-López, Carlos Alemán, David Zanuy J. Peptide Science, doi: 10.1002/psc.1321 (2011)
Genome-wide association study implicates PARD3B-based AIDS restriction Troyer, J.L., Nelson, G.W., Lautenberger, J.A., Chinn, L., McIntosh, C., Johnson, R.C., Sezgin, E., Kessing, B., Malasky, M., Hendrickson, S.L., Li, G., Pontius, J., Tang, M., An, P., Winkler, C.A., Limou, S., Le Clerc, S., Delaneau, O., Zagury, J.-F., Schuitemaker, H., van Manen, D., Bream, J.H., Gomperts, E.D., Buchbinder, S., Goedert, J.J., Kirk, G.D., O'Brien, S.J. J. Infect. Dis 203(10):1491-502 (2011)
De novo Synthesis and Expression of a Thermostable Xylanase from Geobacillus stearothermophilus in Escherichia coli Zhang Zhigang, Pei Xiaoqiong & Wu Zhongliu Chin. J. Appl. Environ. Biol., doi: 10.3724/SP.J.1145.2009.00271 (2011)

2010 (96 papers)

Polymorphic C-terminal β-sheet interactions determine the formation of fibril or ADDL-like globulomer for the Alzheimer Aβ42 dodecamer Buyong Ma and Ruth Nussinov J. Biol. Chem. , doi: 10.1074/jbc.M110.133488 (2010)
Patterns and Complexity in Biological Systems: A Study of Sequence Structure and Ontology-based Networks Kimberley Glass PhD thesis, University of Maryland. (2010)
Dependence of Protein Folding Stability and Dynamics on the Density and Composition of Macromolecular Crowders Jeetain Mittal and Robert B Best BIophys. J. 98(2):315-320 (2010)
Predicting In Vitro Drug Sensitivity using Random Forests Gregory Riddick, Hua Song, Susie Ahn, Jennifer Walling, Diego Borges-Rivera, Wei Zhang, and Howard A. Fine Bioinformatics, published online 5 Dec (2010)

Large-Scale Phosphoproteomic Analysis of Membrane Proteins in Renal Proximal and Distal Tubule Marina Feric, Boyang Zhao, Jason D. Hoffert, Trairak Pisitkun, and Mark A. Knepper Am. J. Physiol. - Cell Physiol. , doi: 10.1152/ajpcell.00360.2010 (2010)
Microarray Meta-Miner (MMM): An integrated method and a web tool to identify genes with similar expression profile Nagarajan, V.; Varma, S.; Hurt, D.; Yongjian Guo; Huyen, Y Computer Technology and Development, doi:10.1109/ICCTD.2010.5646068 (2010)
Atomic-Scale Simulations Confirm that Soluble β-Sheet-Rich Peptide Self-Assemblies Provide Amyloid Mimics Presenting Similar Conformational Properties Xiang Yu, Jingdai Wang, Jui-Chen Yang, Qiuming Wang, Stephen Z.D. Cheng, Ruth Nussinov, and Jie Zheng Biophys. J. 98(1):27-36 (2010)
Nonspecific binding limits the number of proteins in a cell and shapes their interaction networks Margaret E. Johnson and Gerhard Hummer PNAS, doi: 10.1073/pnas.1010954108 (2010)
Molecular Architectures of Trimeric SIV and HIV-1 Envelope Glycoproteins on Intact Viruses: Strain-Dependent Variation in Quaternary Structure Tommi A. White, Alberto Bartesaghi, Mario J. Borgnia, Joel R. Meyerson, M. Jason V. de la Cruz, Julian W. Bess, Rachna Nandwani, James A. Hoxie, Jeffrey D. Lifson, Jacqueline L. S. Milne, Sriram Subramaniam PLoS Pathogens, doi:10.1371/journal.ppat.1001249 (2010)
Nanoscale architecture of integrin-based cell adhesions Kanchanawong P, Shtengel G, Pasapera AM, Ramko EB, Davidson MW, Hess HF, Waterman CM. Nature 468(7323):580-4 (2010)

Accounting for multiple comparisons in a genome-wide association study (GWAS) Randall C Johnson, George W Nelson, Jennifer L Troyer, James A Lautenberger, Bailey D Kessing, Cheryl A Winkler, Stephen J O'Brien BMC Genomics 11:724 (2010)
Stability tests on known and misfolded structures with discrete and all atom molecular dynamics simulations Sijung Yun and Robert H Guy J. Mol. Graph. and Modeling, doi:10.1016/j.jmgm.2010.12.002 (2010)
Free-energy landscape of the GB1 hairpin in all-atom explicit solvent simulations with different force fields: Similarities and differences Robert B Best, Jeetain Mittal Proteins: Structure, Function and Bioinf, doi: 10.1002/prot.22972 (2010)
The Human Glucocorticoid Receptor as an RNA-Binding Protein: Global Analysis of Glucocorticoid Receptor-Associated Transcripts and Identification of a Target RNA Motif Ishmael FT, Fang X, Houser KR, Pearce K, Abdelmohsen K, Zhan M, Gorospe M, Stellato C. J. Immunol. , doi:10.4049/jimmunol.1001794 (2010)
Comprehensive engineering of Escherichia coli for enhanced expression of IgG antibodies Tomohiro Makinoa, Georgios Skretas, Tae Hyun Kang and George Georgiou Metabolic Engg. , doi:10.1016/j.ymben.2010.11.002 (2010)
Analysis of progression-free survival data using a discrete time survival model that incorporates measurements with and without diagnostic error Sally Hunsberger, Paul S Albert, Lori Dodd Clinical Trials, doi: 10.1177/1740774510384887 (2010)

Microscopic properties of nanopore water from its time-dependent dielectric response Jürgen Köfinger and Christoph Dellago Phy. Rev. B 82:205416 (2010)
Detecting sequence polymorphisms associated with meiotic recombination hotspots in the human genome Jie Zheng, Pavel P Khil, R Daniel Camerini-Otero and Teresa M Przytycka Genome Biology 11:R103, doi:10.1186/gb-2010-11-10-r103 (2010)
Expression of Recombinant Cytochromes c in E. coli. Yuri Londer Methods in Molecular Biology 705:123-150 (2010)
Analysis of the stabilities of hexameric amyloid-β (1-42) models using discrete molecular dynamics simulations Sijung Yun, Sajung Yun and H. Robert Guy J. Mol. Graphics and Modelling, doi:10.1016/j.jmgm.2010.11.008 (2010)
Crystal Structures Exploring the Origins of the Broader Specificity of Escherichia coli Heat-Labile Enterotoxin Compared to Cholera Toxin Holmner A, Mackenzie A, Okvist M, Jansson L, Lebens M, Teneberg S, Krengel U. J. Mol. Biol. , doi:10.1016/j.jmb.2010.11.060 (2010)
RAId_aPS: MS/MS Analysis with Multiple Scoring Functions and Spectrum-Specific Statistics Gelio Alves, Aleksey Y. Ogurtsov, and Yi-Kuo Yu PLoS One 5(11):e15438 (2010)
Origin of Twist-Bend Coupling in Actin Filaments Enrique M. De La Cruz, Jeremy Roland, Brannon R. McCullough, Laurent Blanchoin, Jean-Louis Martiel Biophys. J. , doi:10.1016/j.bpj.2010.07.009 (2010)
Approximating probabilities of correlated events Li QiZhai, Zheng Gang, Liu AiYi, Li ZhaoHai & Yu Kai Science China Mathematics 53(11):2937-2948 (2010)
Dockomatic-automated ligand creation and docking Casey W Bullock , Reed B Jacob , Owen M McDougal, Greg Hampikian and Tim Andersen BMC Research Notes, doi:10.1186/1756-0500-3-289 (2010)
Water in the Polar and Nonpolar Cavities of the Protein Interleukin-1β Hao Yin, Guogang Feng, G. Marius Clore, Gerhard Hummer, and Jayendran C. Rasaiah J. Phy. Chem. B, doi: 10.1021/jp108731r (2010)
Assigning statistical significance to proteotypic peptides via database searches Gelio Alves, Aleksey Ogurtsov, Yi-Kuo Yu J. Proteomics, doi:10.1016/j.jprot.2010.10.005 (2010)
A Computational Investigation of the Nitrogen-Boron Interaction in o-(N, N-Dialkylaminomethyl) arylboronate Systems Joseph D. Larkin, John S. Fossey, Tony D. James, Bernard R. Brooks, and Charles W. Bock J. Phys. Chem. A, doi: 10.1021/jp1087674 (2010)

Multiple imputation for estimating the risk of developing dementia and its impact on survival Binbing Yu, Jane S. Saczynski, Lenore Launer Biometrical Journal 52(5) :616-627 (2010)
Pore opening and closing of a pentameric ligand-gated ion channel Fangqiang Zhu and Gerhard Hummer PNAS, doi: 10.1073/pnas.1009313107 (2010)
Protein Simulations with an Optimized Water Model: Cooperative Helix Formation and Temperature-Induced Unfolded State Collapse Robert B Best and Jeetain Mittal J. Phys. Chem. B, doi: 10.1021/jp108618d (2010)
Nematic Order in Small Systems: Measuring the Elastic and Wall-Anchoring Constants in Vibrofluidized Granular Rods Jennifer Galanis, Ralph Nossal, Wolfgang Losert, and Daniel Harries Phys. Rev. Let. 105:168001 (2010)
β-Barrel Topology of Alzheimer's β-Amyloid Ion Channels Hyunbum Jang, Fernando Teran Arce, Srinivasan Ramachandran, Ricardo Capone, Ratnesh Lal, and Ruth Nussinov J. Mol. Biol. , doi:10.1016/j.jmb.2010.10.025 (2010)
Quantitative protein and mRNA profiling shows selective post-transcriptional control of protein expression by vasopressin in kidney cells Sookkasem Khositseth, Trairak Pisitkun, Dane H. Slentz, Guanghui Wang, Jason D. Hoffert, Mark A. Knepper* and Ming-Jiun Yu Molecular & Cellular Proteomics, doi: 10.1074/mcp.M110.004036 (2010)
An approach for jointly modeling multivariate longitudinal measurements and discrete time-to-event data Paul S. Albert and Joanna H. Shih Ann. Appl. Stat. 4(3):1517-1532 (2010)
Electrostatic Interactions and Binding Orientation of HIV-1 Matrix Studied by Neutron Reflectivity Hirsh Nanda, Siddhartha A.K. Datta, Frank Heinrich, Mathias L�sche, Alan Rein, Susan Krueger, Joseph E. Curtis Biophys. J. , doi: 10.1016/j.bpj.2010.07.062 (2010)
Biological Validation of Increased Schizophrenia Risk With NRG1, ERBB4, and AKT1 Epistasis via Functional Neuroimaging in Healthy Controls Kristin K. Nicodemus, Amanda J. Law, Eugenia Radulescu, Augustin Luna, Bhaskar Kolachana, Radhakrishna Vakkalanka, Dan Rujescu, Ina Giegling, Richard E. Straub, Kate McGee, Bert Gold, Michael Dean, Pierandrea Muglia, Joseph H. Callicott, Hao-Yang Tan, Daniel R. Weinberger Arch. Gen. Psych. 67(10):991-1001 (2010)
Conformational Profile of a Proline-Arginine Hybrid Guillermo Revilla-López, Ana I. Jiménez, Carlos Cativiela, Ruth Nussinov, Carlos Alemán, and David Zanuy J. Chem. Inf. and Modeling, doi: 10.1021/ci100135f (2010)
Mapping mouse IL-13 binding regions using structure modeling, molecular docking, and high-density peptide microarray analysis Satish K Madala, Michael A. Dolan, Deepak Sharma, Thirumalai R. Ramalingam, Mark S. Wilson, Margaret M. Mentink-Kane, Daniel C. Masison, Thomas A. Wynn Proteins: Structure, Function and Bioinf, doi: 10.1002/prot.22881 (2010)
Robust and accurate data enrichment statistics via distribution function of sum of weights. Stojmirovic A, Yu YK Bioinformatics, doi: 10.1093/bioinformatics/btq511 (2010)

Using Principal Components of Genetic Variation for Robust and Powerful Detection of Gene-Gene Interactions in Case-Control and Case-Only Studies Samsiddhi Bhattacharjee, Zhaoming Wang, Julia Ciampa, Peter Kraft, Stephen Chanock, Kai Yu and Nilanjan Chatterjee Am. J. Hum. Genet. 86(3):331-342 (2010)
Crystal structure of Lon protease: molecular architecture of gated entry to a sequestered degradation chamber Sun-Shin Cha1, Young Jun An, Chang Ro Lee, Hyun Sook Lee, Yeon-Gil Kim, Sang Jin Kim, Kae Kyoung Kwon, Gian Marco De Donatis, Jung-Hyun Lee, Michael R Maurizi and Sung Gyun Kang Embo J. , doi:10.1038/emboj.2010.226 (2010)
Models of membrane-bound Alzheimer's abeta peptide assemblies Yinon Shafrir, Stewart Durell, Nelson Arispe, H. Robert Guy Proteins, doi: 10.1002/prot.22853 (2010)
In Vitro Selection of Highly Darunavir-Resistant and Replication-Competent HIV-1 Variants by Using a Mixture of Clinical HIV-1 Isolates Resistant to Multiple Conventional Protease Inhibitors Yasuhiro Koh, Masayuki Amano, Tomomi Towata, Matthew Danish, Sofiya Leshchenko-Yashchuk, Debananda Das, Maki Nakayama, Yasushi Tojo, Arun K. Ghosh, and Hiroaki Mitsuya J. Virol. , doi:10.1128/JVI.00967-10 (2010)
Structural and Dynamic Determinants of Ligand Binding and Regulation of Cyclin-Dependent Kinase 5 by Pathological Activator p25 and Inhibitory Peptide CIP A. Cardone, S.A. Hassan, R.W. Albers, R.D. Sriram and H.C. Pant J. Mol. Biol., doi:10.1016/j.jmb.2010.06.040 (2010)
Hollow core of Alzheimer's Aβ42 amyloid observed by cryoEM is relevant at physiological pH Yifat Miller, Buyong Ma, Chung-Jung Tsai, Ruth Nussinov PNAS, 10.1073/pnas.1004704107 (2010)

Population dynamics of a pathogen: the conundrum of vivax malaria Philip G. McQueen Biophys. Revs. 2(3):111-120 (2010)
Scaling Factors and Uncertainties for ab Initio Anharmonic Vibrational Frequencies Russell D. Johnson, III, Karl K. Irikura, Raghu N. Kacker and Rdiger Kessel J. Chem. Theory. Comp., doi: 10.1021/ct100244d (2010)
Molecular Basis for the Structural Stability of an Enclosed β Barrel Loop Pu Tian and Harris D. Bernstein J. Mol. Biol. , doi:10.1016/j.jmb.2010.07.035 (2010)
Predictive Correlations Based on Large Experimental Datasets: Critical Constants for Pure Compounds Andrei Kazakov, Chris D. Muzny, Vladimir Diky, Robert D. Chirico and Michael Frenkel Fluid Phase Equilibria 298(1):131-142 (2010)
Using Cases to Strengthen Inference on the Association between Single Nucleotide Polymorphisms and a Secondary Phenotype in Genome-Wide Association Studies Huilin Li, Mitchell H. Gail, Sonja Berndt, and Nilanjan Chatterjee Genet. Epidemiol. 34(5):427-433 (2010)
Lysine120 Interactions with p53 Response Elements can Allosterically Direct p53 Organization Yongping Pan and Ruth Nussinov PLoS Computational Biology, doi: 10.1371/journal.pcbi.1000878. (2010)
Release of genotype 1 hepatitis E virus from cultured hepatoma and polarized intestinal cells depends on ORF3 protein and requires an intact PXXP motif Suzanne U. Emerson, Hanh T. Nguyen, Udana Torian, Danielle Burke, Ronald Engle and Robert H. Purcell J. Virol. , doi:10.1128/JVI.00593-10 (2010)
Structural Convergence Among Diverse, Toxic β-Sheet Ion Channels Hyunbum Jang, Fernando Teran Arce, Srinivasan Ramachandran, Ricardo Capone, Ratnesh Lal and Ruth Nussinov J. Phys. Chem. B, doi: 10.1021/jp104073k (2010)
The Influence of GABRA2, Childhood Trauma and their Interaction on Alcohol, Heroin and Cocaine Dependence Mary-Anne Enoch, Colin A Hodgkinson, Qiaoping Yuan, Pei-Hong Shen, David Goldman, Alec Roy Biol Psychiatry., doi: 10.1016/j.biopsych.2009.08.019 (2010)
Genome-wide association identifies candidate genes that influence the human electroencephalogram Colin A. Hodgkinson, Mary-Anne Enoch, Vibhuti Srivastava et al. PNAS, doi: 10.1073/pnas.0908134107 (2010)
Multiple chronic pain states are associated with a common amino acid�changing allele in KCNS1 Michael Costigan, Inna Belfer, Robert S. Griffin et al. Brain, doi: 10.1093/brain/awq195 (2010)
Haplotype-Based Study of the Association of Alcohol Metabolizing Genes with Alcohol Dependence in Four Independent Populations Jixia Liu, Zhifeng Zhou, Colin A. Hodgkinson, Qiaoping Yuan, Pei-Hong Shen, Connie J. Mulligan, Alex Wang, Rebecca R. Gray, Alec Roy, Matti Virkkunen, David Goldman, Mary-Anne Enoch Alcohol Clin Exp Res., doi: 10.1111/j.1530-0277.2010.01346.x (2010)
Mutations from a family-shuffling-library reveal amino acid residues responsible for the thermostability of endoglucanase CelA from Clostridium thermocellum Zhuo-Lin Yi and Zhong-Liu Wu Biotech. Letters, 10.1007/s10529-010-0363-0 (2010)
Rational design of an orthogonal tryptophanyl nonsense suppressor tRNA Randall A. Hughes and Andrew D. Ellington Nucleic Acids Research, doi:10.1093/nar/gkq521 (2010)
Phosphoproteomic profiling reveals vasopressin-regulated phosphorylation sites in collecting duct Bansal AD, Hoffert JD, Pisitkun T, Hwang S, Chou CL, Boja ES, Wang G, Knepper MA. J. Am. Soc. Nephrol. 21(2):303-15 (2010)
De novo structure generation using chemical shifts for proteins with high-sequence identity but different folds Shen Y, Bryan PN, He Y, Orban J, Baker D, Bax A. Protein Science 19(2):349-56 (2010)
Balance between α and β Structures in Ab Initio Protein Folding Robert B. Best and Jeetain Mittal J. Phys. Chem. B , doi: 10.1021/jp102575b (2010)
Tautomerism and Magnesium Chelation of HIV-1 Integrase Inhibitors: A Theoretical Study Chenzhong Liao and Marc C. Nicklaus Chem Med Chem, published online 8 Jun (2010)

FastMEDUSA: A parallelized tool to infer gene regulatory networks Serdar Bozdag, Aiguo Li, Stefan Wuchty, Howard A. Fine Bioinformatics, doi:10.1093/bioinformatics/btq275 (2010)
Structural basis of G protein-coupled receptor-G protein interactions Jianxin Hu, Yan Wang, Xiaohong Zhang, John R Lloyd, Jian Hua Li, Joel Karpiak, Stefano Costanzi, J¨rgen Wess Nature Chem. Biol., doi:10.1038/nchembio.385 (2010)
Antimicrobial Protegrin-1 Forms Ion Channels: Molecular Dynamic Simulation, Atomic Force Microscopy, and Electrical Conductance Studies Ricardo Capone, Mirela Mustata, Hyunbum Jang, Fernando Teran Arce, Ruth Nussinov, and Ratnesh Lal Biophys. J., doi: 10.1016/j.bpj.2010.02.024 (2010)
Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types Jeffery B. Klauda, Richard M. Venable, J. Alfredo Freites, Joseph W. O'Connor, Douglas J. Tobias, Carlos Mondragon-Ramirez, Igor Vorobyov, Alexander D. MacKerell, Jr. and Richard W. Pastor J. Phys. Chem. B, published online 24 May (2010)
Comparison of multivariate classifiers and response normalizations for pattern-information fMRI Masaya Misaki, Youn Kima, Peter A. Bandettini and Nikolaus Kriegeskorte Neuroimage, doi:10.1016/j.neuroimage.2010.05.051 (2010)
Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain J. Raphael Gibbs, Marcel P. van der Brug, Dena G. Hernandez, Bryan J. Traynor, Michael A. Nalls, Shiao-Lin Lai, Sampath Arepalli, Allissa Dillman, Ian P. Rafferty, Juan Troncoso, Robert Johnson, H. Ronald Zielke, Luigi Ferrucci, Dan L. Longo, Mark R. Cookson, Andrew B. Singleton PLoS Genetics 6(5):e1000952, doi:10.1371/journal.pgen.1000952 (2010)

Zinc ions promote Alzheimer Aβ aggregation via population shift of polymorphic states Yifat Miller, Buyong Ma, and Ruth Nussinov PNAS, published online 6 May (2010)
Efficient expression and purification of human aglycosylated Fcγ receptors in Escherichia coli Sang Taek Jung, Tae Hyun Kang, George Georgiou Biotech. and Bioengg., published online 7 May (2010)
Emotional Automaticity Is a Matter of Timing Qian Luo, Tom Holroyd, Catherine Majestic, Xi Cheng, Julia Schechter, and R. James Blair J. Neuroscience 30(17):5825-5829 (2010)
How Does the Reductase Help To Regulate the Catalytic Cycle of Cytochrome P450 3A4 Using the Conserved Water Channel? Dan Fishelovitch, Sason Shaik, Haim J. Wolfson and Ruth Nussinov J. Phys. Chem. B 114(17):5964-5970 (2010)
Improving polyp detection algorithms for CT colonography: Pareto front approach Adam Huang, Jiang Li, Ronald M. Summers, Nicholas Petrick, Amy K. Hara Pattern Recognition Letters, doi:10.1016/j.patrec.2010.03.013 (2010)
Solution conformation and dynamics of the HIV-1 integrase core domain Nicholas C. Fitzkee, James E. Masse, Yang Shen, David R. Davies, and Ad Bax J. Biol. Chem. , doi/10.1074/jbc.M110.113407 (2010)
Use of Multiple Assays Subject to Detection Limits With Regression Modeling in Assessing the Relationship Between Exposure and Outcome Albert, Paul S, Harel, Ofer, Perkins, Neil, Browne, Richard Epidemiology, doi: 10.1097/EDE.0b013e3181ce9eed (2010)
Low-Temperature Dynamic Nuclear Polarization at 9.4 Tesla With a 30 Milliwatt microwave source Kent R. Thurber, Wai-Ming Yau and Robert Tycko J. Magnetic Resonance :doi:10.1016/j.jmr.20 (2010)
Neural substrates of graphomotor sequence learning: A combined fMRI and kinematic study Bruce A. Swett, Jose L. Contreras-Vidal, Rasmus Birn and Allen R. Braun J. Neurophysiol., doi:10.1152/jn.00449.2009 (2010)
Extensive and Modular Intrinsically Disordered Segments in C. elegans TTN-1 and Implications in Filament Binding, Elasticity and Oblique Striation Jeffrey G. Forbes, Denise B. Flaherty, Kan Ma, Hiroshi Qadota, Guy M. Benian, and Kuan Wang J. Mol. Biol. , doi:10.1016 (2010)
A Novel Point Mutation in Helix 10 of the Human Glucocorticoid Receptor Causes Generalized Glucocorticoid Resistance by Disrupting the Structure of the Ligand-Binding Domain Nancy Nader, Bert E. Bachrach, Darrell E. Hurt, Sonia Gajula, Amy Pittman, Rachel Lescher, and Tomoshige Kino J. Clin. Endocrin. & Metab., published online 24 March (2010)
Engineering anti-VEGF disulfide-stabilized single chain antibody variable fragments (sc-dsFv) with phage displayed sc-dsFv libraries Yi-Jen Huang, Ing-Chien Chen, Chung-Ming Yu, Yu-Ching Lee, Hung-Ju Hsu, Anna Ching-Ching Tung, Hung-Ju Chang and An-Suei Yang J. Biol. Chem. , published online 12 Jan (2010)
Engineering Anti-vascular Endothelial Growth Factor Single Chain Disulfide-stabilized Antibody Variable Fragments (sc-dsFv) with Phage-displayed sc-dsFv Libraries Yi-Jen Huang, Ing-Chien Chen, Chung-Ming Yu, Yu-Ching Lee, Hung-Ju Hsu, Anna Tung Ching Ching, Hung-Ju Chang, An-Suei Yang J. Biol. Chem. 285:7880-7891 (2010)
Depletion forces drive polymer-like self-assembly in vibrofluidized granular materials Jennifer Galanis, Ralph Nossal, and Daniel Harries Soft Matter 6:1026-1034 (2010)
The behaviour of random forest permutation-based variable importance measures under predictor correlation Kristin Nicodemus, James Malley, Carolin Srobl, Andreas Ziegler BMC Bioinformatics 11:110 (2010)
Molecular Dynamics Reveal the Essential Role of Linker Motions in the Function of Cullin-RING E3 Ligases Jin Liu and Ruth Nussinov J. Mol. Biol. 396(5):1508-1523 (2010)
Quantitative phosphoproteomic analysis reveals vasopressin V2-receptor-dependent signaling pathways in renal collecting duct cells Markus M. Rinschen, Ming-Jiun Yu, Guanghui Wang, Emily S. Boja, Jason D. Hoffert, Trairak Pisitkun, and Mark A. Knepper PNAS, doi/10.1073/pnas.0910646107 (2010)
Noncoding RNA Gas5 Is a Growth Arrest-and Starvation-Associated Repressor of the Glucocorticoid Receptor Tomoshige Kino, Darrell E. Hurt, Takamasa Ichijo, Nancy Nader, and George P. Chrousos Sci. Signal. 3(107):ra8 (2010)

Functional Significance for an Heterogenous Ribonucleoprotein A18 (hnRNP A18) Signature RNA Motif in the 3'UTR of Ataxia Telengiectasia Mutated and RAD3 Related (ATR) Transcript Ruiqing Yang, Ming Zhan, Narasimha Rao Nalabothula, Qingyuan Yang, Fred E. Indig and France Carrier J. Biol. Chem., published online 26 Jan (2010)
Evidence of statistical epistasis between DISC1, CIT and NDEL1 impacting risk for schizophrenia: biological validation with functional neuroimaging Kristin K. Nicodemus, Joseph H. Callicott, Rachel G. Higier, Augustin Luna, Devon C. Nixon, Barbara K. Lipska, Radhakrishna Vakkalanka, Ina Giegling, Dan Rujescu, David St. Clair, Pierandrea Muglia, Yin Yao Shugart and Daniel R. Weinberger Human Genetics 10.1007:s00439-009-0782-y (2010)
Meta-analysis of genome-wide association data detects a risk locus for major mood disorders on chromosome 3p21. 1 Francis J McMahon, Nirmala Akula, Thomas G Schulze, Pierandrea Muglia, Federica Tozzi, Sevilla D Detera-Wadleigh, C J M Steele, René Breuer, Jana Strohmaier, Jens R Wendland, Manuel Mattheisen, Thomas W Mühleisen, Wolfgang Maier, Markus M Nöthen, Sven Cichon, Anne Farmer, John B Vincent, Florian Holsboer, Martin Preisig & Marcella Rietschel for the Bipolar Disorder Genome Study (BiGS) Consortium Nature Genetics 42:128-131 (2010)
Interfacial thermodynamics of confined water near molecularly rough surfaces Jeetain Mittal and Gerhard Hummer Faraday Discussions: Wetting Dynamics of Hydrophobic and Str (2010)
Genetic Crossovers Are Predicted Accurately by the Computed Human Recombination Map Pavel P. Khil and R. Daniel Camerini-Otero PLoS Genetics 6(1):e1000831 (2010)
Genome Wide Association for Addiction: Replicated Results and Comparisons of Two Analytic Approaches Tomas Drgon, Ping-Wu Zhang, Catherine Johnson, Donna Walther, Judith Hess, Michelle Nino, and George R. Uhl PLoS One 5(1):e8832 (2010)
Construction of synthetic open reading frame encoding human interferon alpha 2b for high expression in Escherichia coli and characterization of its gene product Debbie S. Retnoningrum, Ratih A. Ningruma, Yohanes N. Kurniawana, Ana Indrayatia and Heni Rachmawati J. Biotechnol. 145(2):193-198 (2010)
JAGS Version 2.2.0 user manual Martyn Plummer Testing of JAGS was carried out on Helix. (2010)

2009 (86 papers)

Preferred drifting along the DNA major groove and cooperative anchoring of the p53 core domain: mechanisms and scenarios Yongpin Pan and Ruth Nussinov J. Mol. Recognit. 23(2):232-40 (2009)
Computational Investigation of the Oxidative Deboronation of Boroglycine, H2N-CH2-B (OH) 2, Using H2O and H2O2 Larkin JD, Markham GD, Milkevitch M, Brooks BR, Bock CW. J. Phys. Chem. A 113(41):11028-34 (2009)
Modeling Familial Association of Ages at Onset of Disease in the Presence of Competing Risk Joanna Shih and Paul S Albert Biometrics, published online 9 Dec (2009)
JAGS v2.0 Martyn Plummer (2009)

Prediction of Xaa-Pro peptide bond conformation from sequence and chemical shifts Yang Shen and Ad Bax J. Biomolec. NMR 10.1007:s10858-009-9395-y (2009)
Homology modeling and molecular dynamics simulations of HgiDII methyltransferase in complex with DNA and S-adenosyl-methionine: Catalytic mechanism and interactions with DNA Juan A. Castelán-Vega, Alicia Jiménez-Alberto and Rosa M. Ribas-Aparicio J. Molecular Modeling 10.1007:s00894-009-0632-9 (2009)
An experimentally based computer search identifies unstructured membrane-binding sites in proteins: Application to class-I myosins, PAKs and CARMIL Hanna Brzeska, Jake Guag, Kirsten Remmert, Susan Chacko and Edward D. Korn J. Biol. Chem. 285:5738-5747 (2009)
Using Compressibility Factor as a Predictor of Confined Hard-Sphere Fluid Dynamics Jeetain Mittal J. Phys. Chem. B 113(42):13800-13804 (2009)
Prediction of Potency of Protease Inhibitors Using Free Energy Simulations with Polarizable Quantum Mechanics-Based Ligand Charges and a Hybrid Water Model Debananda Das, Yasuhiro Koh, Yasushi Tojo, Arun K. Ghosh and Hiroaki Mitsuya J. Chem. Inf. Mod. 49(12):2851-2862 (2009)
Misfolded Amyloid Ion Channels Present Mobile β-Sheet Subunits in Contrast to Conventional Ion Channels Hyunbum Jang, Fernando Teran Arce, Ricardo Capone, Srinivasan Ramachandran, Ratnesh Lal, and Ruth Nussinov Biophys. J. 97(11):3029-3037 (2009)

Effectiveness of Hair Bundle Motility as the Cochlear Amplifier Bora Sul and Kuni H. Iwasa Biophys. J. 97(10):2653-2663 (2009)
Oligonucleotide Design and Codon Optimization for PCR-based Gene Synthesis Paul Jamesen Steiner Master's Thesis, MIT (2009)
Symmetry-restrained molecular dynamics simulations improve homology models of potassium channels. Anishkin A, Milac AL, Guy HR. Proteins 78(4):932-949 (2009)
Electrophysiological investigation of prestin function: Impact of cysteine replacement and characterization of self-association during voltage stimulation Ryan M. McGuire PhD Thesis, Rice University (2009)
NF90 selectively represses the translation of target mRNAs bearing an AU-rich signature motif Yuki Kuwano, Rudolf Pullmann, Jr., Bernard S. Marasa, Kotb Abdelmohsen, Eun Kyung Lee, Xiaoling Yang, Jennifer L. Martindale, Ming Zhan and Myriam Gorospe Nucleic Acids Research 38(1):225-38 (2009)
Thermodynamic Perspective on the Dock-Lock Growth Mechanism of Amyloid Fibrils ? Edward P. O'Brien, Yuko Okamoto, John E. Straub, Bernard R. Brooks and D. Thirumalai J. Phys. Chem. B 113(43):14421-14430 (2009)

MicroRNA Expression in Squamous Cell Carcinoma and Adenocarcinoma of the Esophagus: Associations with Survival Ewy A. Mathé, Giang Huong Nguyen, Elise D. Bowman, Yiqiang Zhao, Anuradha Budhu, Aaron J. Schetter, Rosemary Braun, Mark Reimers, Kensuke Kumamoto, Duncan Hughes, Nasser K. Altorki, Alan G. Casson, Chang-Gong Liu, Xin Wei Wang, Nozomu Yanaihara, Nobutoshi Hagiwara, Andrew J. Dannenberg, Masao Miyashita, Carlo M. Croce and Curtis C. Harris Clin. Cancer. Res. 15:6192 (2009)
K3 Fragment of Amyloidogenic β2-Microglobulin Forms Ion Channels: Implication for Dialysis Related Amyloidosis Mirela Mustata, Ricardo Capone, Hyunbum Jang, Fernando Teran Arce, Srinivasan Ramachandran, Ratnesh Lal and Ruth Nussinov J. Am. Chem. Soc. 131(41):14938-14945 (2009)
Modeling Aqueous Solvent Effects through Local Properties of Water S.A. Hassan and E.L. Mehler , in Modeling Solvent Environments, Ed. M. Feig, Wiley-VCH (2009)
Evidence for a Partially Structured State of the Amylin Monomer Sara M. Vaiana, Robert B. Best, Wai-Ming Yau, William A. Eaton, and James Hofrichter Biophys. J. 97(11):2948-2957 (2009)
The Mechanism of Ubiquitination in the Cullin-RING E3 Ligase Machinery: Conformational Control of Substrate Orientation Jin Lui and Ruth Nussinov PLoS Computational Biology 5(10):e1000527 (2009)
Generalized Rosenfeld scalings for tracer diffusivities in not-so-simple fluids: Mixtures and soft particles William P. Krekelberg, Mark J. Pond, Gaurav Goel, Vincent K. Shen, Jeffrey R. Errington, Thomas M. Truskett Phys. Rev. E 80:061205 (2009)
Enhanced bacterial expression of several mammalian cytochrome P450s by codon optimization and chaperone coexpression Zhong-Liu Wu, Jing Qiao, Zhi-Gang Zhang, F. Peter Guengerich, Yan Liu and Xiao-Qiong Pei Biotechnology Letters 31(10):1589-1593 (2009)
Theoretical Characterization of Substrate Access/Exit Channels in the Human Cytochrome P450 3A4 Enzyme: Involvement of Phenylalanine Residues in the Gating Mechanism Dan Fishelovitch, Sason Shaik, Haim J. Wolfson, and Ruth Nussinov J. Phys. Chem B 113(39):13018-13025 (2009)
A simple and efficient algorithm for genome-wide homozygosity analysis in disease Wei Liu, Jinhui Ding, Jesse Raphael Gibbs, Sue Jane Wang, John Hardy & Andrew Singleton Molecular Systems Biology 5:304 (2009)
A fast mean-field method for large-scale high-dimensional data and its application in colonic polyp detection at CT colonography Shijun Wang, Ronald M Summers, Changshui Zhang IEEE International Joint Conference on Neural Networks ijcnn:32511-3258 (2009)
Polymorphism of Alzheimer's A β 17-42(p3) Oligomers: The Importance of the Turn Location and Its Conformation Yifat Miller, Buyong Ma, and Ruth Nussinov Biophys. J. 97(4):1168-1177 (2009)
RAId_deNovo: using de novo based spectrum-specific statistics to combine search results from multiple scoring functions and more Gelio Alves, Aleksey Y. Ogurtsov, Yi-Kuo Yu arXiv.org (2009)

Quantitative Mitochondrial Phosphoproteomics Using iTRAQ on an LTQ-Orbitrap with High Energy Collision Dissociation Emily Boja, Darci Phillips, Stephanie A French, Robert A. Harris, and Robert Stephen Balaban J. Proteome Research 8(10):4665-4675 (2009)
Molecular Dynamics Simulations of PIP 2 and PIP 3 in Lipid Bilayers: Determination of Ring Orientation, and the Effects of Surface Zheng Li, Richard M. Venable, Laura A. Rogers, Diana Murray, and Richard W. Pastor Biophys. J. 97(1):155-163 (2009)
Cooperativity Dominates the Genomic Organization of p53-Response Elements: A Mechanistic View Yongpin Pan and Ruth Nussinov PLoS Computational Biology :e1000448. (2009)
Functional but not structural changes associated with learning: An exploration of longitudinal Voxel-Based Morphometry (VBM) Thomas AG, Marrett S, Saad ZS, Ruff DA, Martin A, Bandettini PA. Neuroimage 48(1):117-25 (2009)
Phosphine Polymerization by Nitric Oxide: Experimental Characterization and Theoretical Predictions of Mechanism Yi-Lei Zhao, Jason W. Flora, William David Thweatt, Stephen L. Garrison, Carlos Gonzalez, K. N. Houk and Manuel Marquez Inorg. Chem. 48(3):1223-1231 (2009)
Protein Segments with Conformationally Restricted Amino Acids Can Control Supramolecular Organization at the Nanoscale David Zanuy, Gema Ballano, Ana I. Jimnez, Jordi Casanovas, Nurit Haspel, Carlos Cativiela, David Curc, Ruth Nussinov and Carlos Alemán J. Chem. Info. and Modeling 49(7):1623=9 (2009)

Amygdala function and 5-HTT gene variants in adolescent anxiety and major depressive disorder Lau JY, Goldman D, Buzas B, Fromm SJ, Guyer AE, Hodgkinson C, Monk CS, Nelson EE, Shen PH, Pine DS, Ernst M. Biol. Psychiatry , doi: 10.1016/j.biopsych.2008.08.037 (2009)
HTR3B is associated with alcoholism with antisocial behavior and alpha EEG power�an intermediate phenotype for alcoholism and co-morbid behaviors Ducci F, Enoch MA, Yuan Q, Shen PH, White KV, Hodgkinson C, Albaugh B, Virkkunen M, Goldman D. Alcohol, doi: 10.1016/j.alcohol.2008.09.005 (2009)
Association of Substance Use Disorders With Childhood Trauma but not African Genetic Heritage in an African American Cohort Ducci F, Roy A, Shen PH, Yuan Q, Yuan NP, Hodgkinson CA, Goldman LR, Goldman D. Am. J. Psychiatry, doi: 10.1176/appi.ajp.2009.08071068 (2009)
Kinetic Barriers of H-Atom Transfer Reactions in Alkyl, Allylic, and Oxoallylic Radicals as Calculated by Composite Ab Initio Methods Carrigan J. Hayes and Donald R. Burgess, Jr. J. Phys. Chem. A 113(11):2473-2482 (2009)
On the Mechanism of Nitrosoarene-Alkyne Cycloaddition Andrea Penoni, Giovanni Palmisano, Yi-Lei Zhao, Kendall N. Houk, Jerome Volkman and Kenneth M. Nicholas J. Am. Chem. Soc. 131(2):653-661 (2009)
Artificial reaction coordinate “tunneling” in free-energy calculations: The catalytic reaction of RNase H Edina Rosta, H. Lee Woodcock, Bernard R. Brooks, Gerhard Hummer J. Comput. Chem. 30(11):1634-41 (2009)
Building and assessing atomic models of proteins from structural templates: Learning and benchmarks Brinda Kizhakke Vallat, Jaroslaw Pillardy, Peter M�jek, Jaroslaw Meller, Thomas Blom, BaoQiang Cao, Ron Elber Proteins 76(4):930-945 (2009)
Imaging incorporation of circulating docosahexaenoic acid into the human brain using positron emission tomography John C. Umhau, Weiyin Zhou, Richard E. Carson, Stanley I. Rapoport, Alla Polozova, James Demar, Nahed Hussein, Abesh K. Bhattacharjee, Kaizong Ma, Giuseppe Esposito, Sharon Majchrzak, Peter Herscovitch, William C. Eckelman, Karen A. Kurdziel, and Norman Salem . Jr J. Lipid Res. 50(7):1259-68 (2009)
Error and efficiency of replica exchange molecular dynamics simulations Edina Rosta and Gerhard Hummer J. Chem. Phys. 131:165102 (2009)
Insights Into Crowding Effects on Protein Stability From a Coarse-Grained Model VK Shen, J Cheung, JR Errington, TM Truskett J. Biomech. Engg. 131(7):0710002 (2009)
The bis-Electrophile Diepoxybutane Cross-Links DNA to Human Histones but Does Not Result in Enhanced Mutagenesis in Recombinant Systems Elisabeth M. Loecken, Surendra Dasari, Salisha Hill, David L. Tabb and F. Peter Guengerich Chem. Res. Toxicol. 22(6):1069-1076 (2009)
Revealing the dimer dissociation and existence of a folded monomer of the mature HIV-2 protease Louis JM, Ishima R, Aniana A, Sayer JM. Protein Science 18(12):2442-53 (2009)

Molecular dynamics study of the structure and interparticle interactions of polyethylene glycol-conjugated PAMAM dendrimers Hwankyu Lee and Ronald G. Larson J. Phys. Chem. B 113(40):13202-13207 (2009)
Computer Assisted Analysis of Genes MV Fachal, M Furlan Reproductive Endocrinology Part 2:113-117 (2009)
Optimized Molecular Dynamics Force Fields Applied to the Helix-Coil Transition of Polypeptides Robert B Best, Gerhard Hummer J. Phys. Chem B 113(26):9004-9015 (2009)
Predictor Correlation Impacts Machine Learning Algorithms: Implications for Genomic Studies Kristin K. Nicodemus and James D. Malley Bioinformatics 25:1884-1889 (2009)
A Partially Linear Tree-based Regression Model for Multivariate Outcomes Kai Yu, William Wheeler, Qizhai Li, Andrew W. Bergen, Neil Caporaso, Nilanjan Chatterjee, and Jinbo Chen Biometrics, published online 10 May (2009)
A finite mixture survival model to characterize risk groups of neuroblastoma Sally Hunsberger, Paul S. Albert and Wendy B. London Stat. Med. 28:1301-1314 (2009)
Post-rituximab Burkitt transformation of PTLD: loss of CD20 expression accompanied by a switch in light-chain expression Yu-Yan Hwang, Kai Y. Wong, Rock Y. Y. Leung, Simon H. M. Wong, See-Ching Chan, Gopesh Srivastava and Wing Y. Au Annals of Hematology 89(1):1432-0584 (2009)
De novo protein structure generation from incomplete chemical shift assignments Yang Shen, Robert Vernon, David Baker, and Ad Bax J. Biomol. 43(2):63-78 (2009)
In Silico Molecular Engineering for a Targeted Replacement in a Tumor-Homing Peptide. Zanuy D, Flores-Ortega A, Jiménez AI, Calaza MI, Cativiela C, Nussinov R, Ruoslahti E, Alemán C. J. Phys. Chem. B 113(22):7879-89 (2009)
Widespread Reductions of Cortical Thickness in Schizophrenia and Spectrum Disorders and Evidence of Heritability Aaron L. Goldman, Lukas Pezawas, Venkata S. Mattay, Bruce Fischl, Beth A. Verchinski, Qiang Chen, Daniel R. Weinberger, Andreas Meyer-Lindenberg. Archives of General Psychiatry 66(5):467-477 (2009)
Gene Composer: database software for protein construct design, codon engineering, and gene synthesis Don Lorimer, Amy Raymond, John Walchli. Mark Mixon, Adrienne Barrow, Ellen Wallace, Rena Grice, Alex Burgin, Lance Stewart BMC Biotechnology 9:36 (2009)
Available states and available space: static properties that predict self-diffusivity of confined fluids Gaurav Goel, William P Krekelberg, Mark J Pond, Jeetain Mittal, Vincent K Shen, Jeffrey R Errington and Thomas M Truskett J. Stat. Mech., doi:10.1088/1742-5468/2009/04/P04006 (2009)

Identification of cis-regulatory elements in gene co-expression networks using A-GLAM. Mariño-Ramírez L, Tharakaraman K, Bodenreider O, Spouge J, Landsman D. Methods Mol. Biol. 541:1-22 (2009)
Thermostat Artifacts in Replica Exchange Molecular Dynamics Simulations Edina Rosta, Nicolae-Viorel Buchete and Gerhard Hummer J. Chem. Theory and Computation 5(5):1393-1399 (2009)
Pathway analysis by adaptive combination of P-values Kai Yu, Qizhai Li, Andrew W. Bergen, Ruth M. Pfeiffer, Philip S. Rosenberg, Neil Caporaso, Peter Kraft, Nilanjan Chatterjee Genetic Epidemiology 33(8):700-9 (2009)
Comparison of the Extended Isotropic Periodic Sum and Particle Mesh Ewald Methods for Simulations of Lipid Bilayers and Monolayers Richard M. Venable, Linda E. Chen and Richard W. Pastor J. Phys. Chem B 113(17):5855-5862 (2009)
Genetic background comparison using distance-based regression, with applications in population stratification evaluation and adjustment Qizhai Li, Sholom Wacholder, David J. Hunter, Robert N. Hoover, Stephen Chanock, Gilles Thomas, Kai Yu Genetic Epidemiology 33(5):432-441 (2009)
Self-guided langevin dynamics study of regulatory interactions in NtrC Ana Damjanovic, Betrand Garcia-Moreno E., Bernard R. Brooks Proteins: Structure, Function and Bioinformatics 76(4):1007-19 (2009)
Engineered Integrin Binding Peptides Cochran, Jennifer R., Kimura, Richard, Levin, Aron M., Silverman, Adam, Gambhir, Sanjiv S., Cheng, Zhen, Lahti, Jennifer Patent # 12/418376 (2009)
Different Patterns of Regulation for the Copper and Cadmium Metallothioneins of the Ectomycorrhizal Fungus Hebeloma cylindrosporum G. Ramesh, G. K. Podila, G. Gay, R. Marmeisse, and M. S. Reddy App. Env. Microbiology 75(8):2266-2274 (2009)
Hybrid Structural Model of the Complete Human ESCRT-0 Complex Xuefeng Ren, Daniel P. Kloer, Young C. Kim, Rodolfo Ghirlando, Layla F. Saidi, Gerhard Hummer and James H. Hurley Structure 17(3):406-416 (2009)
Combining heterogeneous features for colonic polyp detection in CTC based on semi-definite programming Shijun Wang ; Jianhua Yao ; Nicholas A. Petrick ; Ronald M. Summers SPIE Proceedings, doi:10.1117/12.811219 (2009)
Identification of active sites of biomolecules II: Saccharide and transition metal ion in aqueous solution Coskuner O, Bergeron DE, Rincon L, Hudgens JW, Gonzalez CA. J. Phys. Chem. A 113(11):2491-9 (2009)
Intramolecular Disulfide Bonds of the Prolactin Receptor Short Form are Required for its Inhibitory Action on the Function of the Long form of the Receptor Y-L. Xie, S. A. Hassan, A. M. Qazi, C. H. Tsai-Morris, and M. L. Dufau Mol. Cell. Biol. 29(10):2546-55 (2009)
Adjacency Method for Finding Connected Subsets of a Graph: An Application of Graph Theory to Spatial Statistics Jun Luo, Lan Huang, Mark Hachey, Ram Tiwari Comm. in Stat.: Simulation and Computation 38(5):1136-1151 (2009)
Genetic Studies on Stuttering Families Muhammed Hashim Raza PhD Thesis, University of the Punjab, Lahore, Pakistan (2009)
Large-scale production and characterization of an engineered human olfactory receptor Brian Lee Cook PhD thesis in Biological Engineering at MIT (2009)
Ionic Hydrogen-Bond Networks and Ion Solvation. 1. An Efficient Monte Carlo/Quantum Mechanical Method for Structural Search and Energy Computations: Ammonium/Water Yi-Lei Zhao, Michael Meot-Ner (Mautner) and Carlos Gonzalez J. Phys. Chem. A 113(12):2967-74 (2009)
Theory and simulation of macromolecular crowding effects on protein folding stability and kinetics Jeetain Mittal and Robert B. Best arXiv.org (2009)
High-Level Production, Solubilization and Purification of Synthetic Human GPCR Chemokine Receptors CCR5, CCR3, CXCR4 and CX3CR1 Hui Ren, Daoyong Yu, Baosheng Ge, Brian Cook, Zhinan Xu, and Shuguang Zhang PLoS ONE 4(2):e4509 (2009)

A Model for Fine Mapping in Family Based Association Studies Stefan Boehringer and Ruth M. Pfeiffer Hum. Heredit. 67(4):226-236 (2009)
The Factor VIIIa C2 Domain (Residues 2228-2240) Interacts with the Factor IXa Gla Domain in the Factor Xase Complex Tetsuhiro Soeda, Keiji Nogami, Katsumi Nishiya, Masahiro Takeyama, Kenichi Ogiwara, Yoichi Sakata, Akira Yoshioka, and Midori Shima J. Biol. Chem. 284(6):3379-3388 (2009)
Proteomic Analysis of Human Urinary Exosomes Patricia Amalia Gonzales Mancilla PhD thesis, U. Maryland (2009)
Optimizing computer-aided colonic polyp detection for CT colonography by evolving the Pareto front Jiang Li, Adam Huang, Jack Yao, Jiamin Liu, Robert L. Van Uitert, Nicholas Petrick, Ronald M. Summers Medical Physics 36:201-212 (2009)
Rigorous treatment of electrostatics for spatially varying dielectrics based on energy minimization O. I. Obolensky, T. P. Doerr, R. Ray, and Yi-Kuo Yu Bulletin of the American Physical Society 54:P40.00008 (2009)
Available states and available space: Static properties that predict dynamics of confined fluids Gaurav Goel, William P. Krekelberg, Mark J. Pond, Jeetain Mittal, Vincent K. Shen, Jeffrey R. Errington, Thomas M. Truskett J. Stat. Mech. :P04006 (2009)
A coarse-grained model for polyethylene oxide and polyethylene glycol: conformation and hydrodynamics. Lee H, de Vries AH, Marrink SJ, Pastor RW. J. Phys. Chem. B 113(40):13186-94 (2009)
Visual Awareness, Emotion, and Gamma Band Synchronization Qian Luo, Derek Mitchell, Xi Cheng, Krystal Mondillo, Daniel McCaffrey, Tom Holroyd, Frederick Carver, Richard Coppola and James Blair Cerebral Cortex 19(8):1896-1904 (2009)
Bayesian Inference for Smoking Cessation with a Latent Cure State Luo S, Crainiceanu, CM, Louis TA, Chatterjee, N Biometrics 65(3):970-8 (2009)
Bio-Sensing Nanodevice Zhang, Shuguang, Mershin, Andreas, Kaiser, Liselotte, Cook, Brian, Graveland-bikker, Johanna F., Prakash, Manu, Kong, David, Maguire, Yael Patent # 12/183916 (2009)

2008 (102 papers)

Dislocation nucleation during nanoindentation of aluminum R. J. Wagner, L. Ma, F. Tavazza, and L. E. Levine J. Applied Physics 104:114311 (2008)
Pathways and populations: stereoelectronic insights into the exocyclic torsion of 5-(hydroxymethyl) tetrahydropyran. Woodcock HL, Brooks BR, Pastor RW. JACS 130(20):6345-7 (2008)

Biological Entity Recognition with Conditional Random Fields Ying He and Mehmet Kayaalp AMIA Annu Symp Proc. 2008:293-297 (2008)
Lipid bilayer curvature and pore formation induced by charged linear polymers and dendrimers: the effect of molecular shape Hwankyu Lee and Ronald G. Larson J. Phys. Chem. B 112(39):12279-12285 (2008)
The point mutation A34F causes dimerization of GB1. JunGoo Jee, In-Ja L. Byeon, John M. Louis, Angela M. Gronenborn Proteins 71(3):1420-31 (2008)
RAId_DbS: mass-spectrometry based peptide identification web server with knowledge integration Alves G, Ogurtsov AY, Yu YK. BMC Genomics 9:505 (2008)
Enhancing peptide identification confidence by combining search methods. Alves G, Wu WW, Wang G, Shen RF, Yu YK J. Proteome Res. 7(8):3102-13 (2008)
Coarse-grained molecular dynamics studies of the concentration and size dependence of fifth-and seventh-generation PAMAM dendrimers on pore formation in DMPC bilayer Hwankyu Lee and Ronald G. Larson J. Phys. Chem. B 112(26):7778-7784 (2008)

RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways Marcel P. van der Brug, Jeff Blackinton, Jayanth Chandran, Ling-Yang Hao, Ashish Lal, Krystyna Mazan-Mamczarz, Jennifer Martindale, Chengsong Xie, Rili Ahmad, Kelly J. Thomas, Alexandra Beilina, J. Raphael Gibbs, Jinhui Ding, Amanda J. Myers, Ming Zhan, Huaibin Cai, Nancy M. Bonini, Myriam Gorospe and Mark R. Cookson PNAS 105(29):10244-10249 (2008)
Influence of the dye presence on the conformational preferences of CREKA, a tumor homing linear pentapeptide. Zanuy D, Curcó D, Nussinov R, Alemán C Biopolymers 92(2):83-93 (2008)
Analysis of Smoking Cessation Patterns Using a Stochastic Mixed-Effects Model With a Latent Cured State Sheng Luo, Ciprian M Crainiceanu, Thomas A Louis, Nilanjan Chatterjee J. Am. Stat. Assoc. 103(483):1002-1013 (2008)
Inference of non-centrality parameter of a truncated non-central chi-squared distribution Qizhai Li and Kai Yu J. Stat. Planning and Inference 139(7):2431-2444 (2008)
Static and dynamic correlations in water at hydrophobic interfaces Jeetain Mittal and Gerhard Hummer PNAS 105:20130-20135 (2008)
Thermodynamics and kinetics of protein folding under confinement Jeetain Mittal and Robert Best PNAS 105(51):20233-8 (2008)

Characterization of a protective Escherichia coli-expressed Plasmodium falciparum merozoite surface protein 3 indicates a non-linear, multi-domain structure Tsai CW, Duggan PF, Jin AJ, Macdonald NJ, Kotova S, Lebowitz J, Hurt DE, Shimp RL Jr, Lambert L, Miller LH, Long CA, Saul A, Narum DL. Mol. Biochem. Parasitol. 164(1):45-56 (2008)
Self-assembly of fused homo-oligomers to create nanotubes Buch I, Tsai CJ, Wolfson HJ, Nussinov R. Methods Mol. Biol. 474:117-31 (2008)
Regulation of a remote Shh forebrain enhancer by the Six3 homeoprotein Yongsu Jeong, Federico Coluccio Leskow, Kenia El-Jaick, Erich Roessler, Maximilian Muenke, Anastasia Yocum, Christele Dubourg, Xue Li, Xin Geng, Guillermo Oliver & Douglas J Epstein Nature Genetics 40:1348-1353 (2008)
Identification of a signature motif in target mRNAs of RNA-binding protein AUF1 Krystyna Mazan-Mamczarz, Yuki Kuwano, Ming Zhan, Elizabeth J. White, Jennifer L. Martindale, Ashish Lal and Myriam Gorospe Nucleic Acids Research 37(1):204-14 (2008)
GRL-02031, a Novel Nonpeptidic Protease Inhibitor (PI) Containing a Stereochemically Defined Fused Cyclopentanyltetrahydrofuran Potent against Multi-PI-Resistant HIV-1 In Vitro Yasuhiro Koh, Debananda Das, Sofiya Leschenko, Hirotomo Nakata, Hiromi Ogata-Aoki, Masayuki Amano, Maki Nakayama, Arun K. Ghosh, and Hiroaki Mitsuya Antimicrob Agents Chemother. 53(3):997-1006 (2008)
A class comparison method with filtering-enhanced variable selection for high-dimensional data sets Lara Lusa, Edward L. Korn, Lisa M. McShane Stat. Med 28:5834-5849 (2008)

Models of voltage-dependent conformational changes in NaChBac channels Shafrir Y, Durell SR, Guy HR. Biophys. J. 95(8):3663-76 (2008)
Prediction of evolutionarily conserved interologs in Mus musculus. Yellaboina S, Dudekula DB, Ko MS. BMC Genomics 9:465 (2008)
Comparing the Use of Gibbs Ensemble and Grand-Canonical Transition-Matrix Monte Carlo Methods to Determine Phase Equilibria Andrew S. Paluch, Vincent K. Shen and Jeffrey R. Errington Ind. Eng. Chem. Res. 47(13):4533-4541 (2008)
Molecular Dynamics Simulations of Perylene and Tetracene Librations: Comparison With Femtosecond Upconversion Data Tilman Rosales, Jianhua Xu, Xiongwu Wu, Milan Hodoscek, Patrik Callis, Bernard R. Brooks and Jay R. Knutson J. Phys. Chem. A 112(25):5593-5597 (2008)
Efficient cell-free production of olfactory receptors: Detergent optimization, structure, and ligand binding analyses Liselotte Kaiser, Johanna Graveland-Bikker, Dirk Steuerwald, Mélanie Vanberghem, Kara Herlihy, and Shuguang Zhang PNAS 105(41):15726-15731 (2008)
Models of Toxic β-Sheet Channels of Protegrin-1 Suggest a Common Subunit Organization Motif Shared with Toxic Alzheimer β-Amyloid Ion Channels. Jang H, Ma B, Lal R, Nussinov R. Biophys. J. 95(10):4631-42 (2008)

Computer Simulation of Ion Cluster Speciation in Concentrated Aqueous Solutions at Ambient Conditions Sergio A. Hassan J. Phys. Chem. B 112:10573-10584 (2008)
Study on allotopic expression of recoded human mitochondrial ND4L genes in mammalian cells Mou-Chieh Kao Master's thesis, National Tsing Hua University, Taiwan (2008)
Considerations for Lipid Force Field Development Jeffery B. Klauda, Richard M. Venable, Alexander D. MacKerell Jr., Richard W. Pastor in Computational Modeling of Membrane Bilayers, in Current Topics in Membranes Vol 60. (2008)
Developmental and epigenetic regulation of the human TLR3 gene Analia Porrás, Sarah Kozar, Valya Russanova, Paraskevi Salpea, Tazuko Hirai, Nicholas Sammons, Pooja Mittal, Ji Young Kim, Keiko Ozato, Roberto Romero and Bruce H. Howard Mol. Immunol. 46(1):27-36 (2008)
Glycosidic linkage conformation of methyl-α-mannopyranoside Orkid Coskuner, Denis E. Bergeron, Luis Rincon, Jeffrey W. Hudgens, and Carlos A. Gonzalez J. Chem. Phys. 129:045102 (2008)
Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways. Lenz G, Wright GW, Emre NC, Kohlhammer H, Dave SS, Davis RE, Carty S, Lam LT, Shaffer AL, Xiao W, Powell J, Rosenwald A, Ott G, Muller-Hermelink HK, Gascoyne RD, Connors JM, Campo E, Jaffe ES, Delabie J, Smeland EB, Rimsza LM, Fisher RI, Weisenburger DD, Chan WC, Staudt LM. PNAS 105(36):13520-5 (2008)

Ligand Exchange Reactions in the Formation of Diphosphine-Protected Gold Clusters Denis E. Bergeron, Orkid Coskuner, Jeffrey W. Hudgens, and Carlos A. Gonzalez J. Phys. Chem. C 112(33):12808-12814 (2008)
Evidence That Proline Focuses Movement of the Floppy Loop of Arylalkylamine N-Acetyltransferase (EC 2.3. 1.87) Jiri Pavlicek, Steven L. Coon, Surajit Ganguly, Joan L. Weller, Sergio A. Hassan, Dan L. Sackett, and David C. Klein J. Biol. Chem. 283(21):14552-14558 (2008)
NEIBank: Genomics and bioinformatics resources for vision research Graeme Wistow, Katherine Peterson, James Gao, Patee Buchoff, Cynthia Jaworski, Catherine Bowes-Rickman, Jessica N. Ebright, Michael A. Hauser, and David Hoover Molecular Vision 14:1327-1337 (2008)
mRNA Distribution and Heterologous Expression of Orphan Cytochrome P450 20A1 Katarina Stark, Zhong-Liu Wu, Cheryl J. Bartleson and F. Peter Guengerich Drug Metabolism and Disposition 36(9):1930-1937 (2008)
Molecular dynamics studies of polyethylene oxide and polyethylene glycol: Hydrodynamic radius and shape anisotropy Hwankyu Lee, Richard M. Venable, Alexander D. MacKerell, Jr. and Richard W. Pastor Biophysical Journal 95(4):1590-9 (2008)
Positron Emission Tomography Imaging Using an Inverse Agonist Radioligand to Assess Cannabinoid CB1 Receptors in Rodents Terry G, Liow J-S, Chernet E; Zoghbi SS, Phebus L, Felder CC, Tauscher J, Schaus JM, Pike VW, Halldin C, Innis RB. Neuroimage 41(3):690-8 (2008)

p53-Induced DNA Bending: The Interplay between p53-DNA and p53-p53 Interactions Yongpin Pan, Ruth Nussinov J. Phys. Chem. B 112(21):6716-24 (2008)
11C-Loperamide and its N-desmethyl radiometabolite are avid substrates for brain P-glycoprotein efflux Zoghbi SS, Liow J-S,Yasuno F, Hong J, Tuan E; Lazarova N, Gladding RL; Pike VW, Innis RB J. Nucl. Med. 49(4):649-56 (2008)
CHARMM Force Field Parameters for Nitroalkanes and Nitroarenes Klauda JB, Brooks BR J. Chem. Theory and Computation 4(1):107-115 (2008)
Binding-induced folding of a natively unstructured transcription factor Turjanski, A. G., Gutkind, J.S., Best, R. and Hummer. G. PLoS Computational Biology, e1000060 doi:10.1371 (2008)
Privileged scaffolds targeting reverse-turn and helix recognition Che, Ye & Marshall, Garland. Expert Opinion on Therapeutic Targets 12(1):101-114 (2008)
Study of a Synthetic Human Olfactory Receptor 17-4: Expression and Purification from an Inducible Mammalian Cell Line Brian L. Cook, Karin E. Ernberg, Hyeyoun Chung, and Shuguang Zhang PLoS One 3(8):e2920 (2008)

Genotype, haplotype and copy-number variation in worldwide human populations. Jakobsson M, Scholz SW, Scheet P, Gibbs JR, VanLiere JM, Fung HC, Szpiech ZA, Degnan JH, Wang K, Guerreiro R, Bras JM, Schymick JC, Hernandez DG, Traynor BJ, Simon-Sanchez J, Matarin M, Britton A, van de Leemput J, Rafferty I, Bucan M, Cann HM, Hardy JA, Rosenberg NA, Singleton AB. Nature 451(7181):998-1003 (2008)
Cluster Without Fluster: The Effect of Correlated Outcomes on Inference in Randomized Clinical Trials Proschan MA, Follmann, DA. Statistics in Medicine 27(6):795-809 (2008)
Sigma Stellation: A Design Strategy for Electron Boxes Irikura, Karl K J. Phys. Chem A 112:983-988 (2008)
Coordination Studies of Al-EDTA in Aqueous Solution Orkid Coskuner, Emily A. A. Jarvis J. Phys. Chem. 112(12):2628-2633 (2008)
Layering and Position-Dependent Diffusive Dynamics of Confined Fluids Jeetain Mittal, Thomas M. Truskett, Jeffrey R. Errington, and Gerhard Hummer Phys. Rev. Let. 100:145901 (2008)
Genetic variation in human NPY expression affects stress response and emotion Zhou Z, Zhu G, Hariri AR, Enoch MA et al. Nature, doi: 10.1038/nature06858 (2008)

Addictions biology: haplotype-based analysis for 130 candidate genes on a single array Hodgkinson CA, Yuan Q, Xu K, Shen PH, Heinz E, Lobos EA, Binder EB, Cubells J, Ehlers CL, Gelernter J, Mann J, Riley B, Roy A, Tabakoff B, Todd RD, Zhou Z, Goldman D. Alcohol and Alcoholism, doi: 10.1093/alcalc/agn032 (2008)
Common Genetic Origins for EEG, Alcoholism and Anxiety: The Role of CRH-BP Enoch MA, Shen PH, Ducci F, Yuan Q, Liu J, White KV, Albaugh B, Hodgkinson CA, Goldman D. PLoS One, doi: 10.1371/journal.pone.0003620 (2008)
Comprehensive Structural Studies of 2', 3'-Difluorinated Nucleosides: Comparison of Theory, Solution, and Solid State Joseph J. Barchi, Jr., Rajeshri G. Karki, Marc C. Nicklaus, Maqbool A. Siddiqui, Clifford George, Igor A. Mikhailopulo and Victor E. Marquez J. Am. Chem. Soc. 130(28):9048-9057 (2008)
A template-finding algorithm and a comprehensive benchmark for homology modeling of proteins Vallat BK, Pillardy J, Elber R. Proteins 72(3):910-28 (2008)
MAX-rank: a simple and robust genome-wide scan for case-control association studies. Li Q, Yu K, Li Z, Zheng G. Hum. Genet. 123(6):617-23 (2008)
Backbone relaxation coupled to the ionization of internal groups in proteins: A self-guided Langevin dynamics study Ana Damjanovic, Xiongwu Wu, Bertrand Garcia-Moreno and Bernard R Brooks Biophys. J. 95(9):4091-101 (2008)
The Cytoplasmic Terminus of Kaposi's Sarcoma-Associated Herpesvirus Glycoprotein B Is Not Essential for Virion Egress and Infectivity{triangledown} R. Subramanian, O. D'Auvergne, Haixia Kong, and K. G. Kousoulas J. Virol. 82(14):7144-7154 (2008)
Expression and purification of orphan cytochrome P450 4X1 and oxidation of anandamide Stark K, Dostalek M, Guengerich FP. FEBS J. 275(14):3706-17 (2008)
Towards an automatic classification of protein structural domains based on structural similarity Sam V, Tai CH, Garnier J, Gibrat JF, Lee B, Munson PJ. BMC Bioinformatics 9(1):74 (2008)
Endogenous retrotransposon sequences of the Schistosoma mansoni intermediate snail host, Biomphalaria glabrata Knight M, Bridger J, Ittiprasert W, Odoemelam E, Masabanda J, Miller A, Raghavan, N. Mobile Genetic Elements in Metazoan Para, Brindley PJ (ed). Landes Bioscience, in press. (2008)
The Imaging Probe Development Center and the Production of Molecular Imaging Probes Gary L Griffiths Curr. Chem. Genomics 1:65-69 (2008)
On estimating diagnostic accuracy from studies with multiple raters and partial gold standard evaluation Paul S. Albert and Lori E Dodd J. Am. Stat. Assoc 103(481):61-73 (2008)
In Situ Gas Phase Diagnostics for Hafnium Oxide Atomic Layer Deposition J.E. Maslar, W.S. Hurst, D.R. Burgess, W.A. Kimes, N.V. Nguyen, E.F. Moore, J.T. Hodges ECS Transactions 13(2):139-149 (2008)
Differences in Cysteine Protease Activity in Schistosoma mansoni-Resistant and-Susceptible Biomphalaria glabrata and Characterization of the Hepatopancreas Cathepsin B Full-length cDNA Jocelyn Myers, Wannaporn Ittiprasert, Nithya Raghavan, André Miller, and Matty Knight J. Parasitol. 94:3:659-668 (2008)
Molecular architecture of native HIV-1 gp 120 trimers Jun Liu, Alberto Bartesaghi, Mario J. Borgnia, Guillermo Sapiro & Sriram Subramaniam Nature 455:109-113 (2008)
Dissecting contact potentials for proteins: relative contributions of individual amino acids Buchete NV, Straub JE, Thirumalai D. Proteins 70(1):119-30 (2008)
Synthesis and evaluation of N-Methyl and S-Methyl 11C-Labeled 6-Methylthio-2-(4'-N,N-dimethylamino)phenylimidazo[1,2-a]pyridines as radioligands for imaging beta-amyloid plaques in Alzheimer's disease Cai L, Liow JS, Zoghbi SS, Cuevas J, Baetas C, Hong J, Shetty HU, Seneca NM, Brown AK, Gladding R, Temme SS, Herman MM, Innis RB, Pike VW. J. Med. Chem. 51(1):148-58 (2008)
Residual multiparticle entropy does not generally change sign near freezing Krekelberg WP, Shen VK, Errington JR, Truskett TM. J. Chem. Phys. 128(16):161101 (2008)

Synthesis and pharmacological effects of the enantiomers of the N-phenethyl analogues of the ortho and para e-and f-oxide-bridged phenylmorphans Josef Zezula, Lisa Singer, Anna K. Przyby, Akihiro Hashimoto, Christina M. Dersch, Richard B. Rothman, Jeffrey Deschamps, Yong Sok Lee, Arthur E. Jacobson and Kenner C. Rice Org. and Biomol. Chem. 6:2868-2883 (2008)
A pseudopotential for improving the packing of ellipsoidal protein structures determined by NMR C.D. Schwieters and G.M. Clore. J. Phys. Chem 112(19):6070-6073 (2008)
PCR-based gene synthesis to produce recombinant proteins for crystallization Damien Marsic, Ronny C Hughes, Miranda L Byrne-Steele and Joseph D Ng BMC Biotechnology 8:44 (2008)
Dynamics of Cholesterol Exchange in the OSBP-Related Protein Family Canagarajah, B., Hummer, G., Prinz, W. and Hurley, J. H. J. Mol. Biol. 378(3):737-48 (2008)
Population Substructure and Control Selection in Genome-Wide Association Studies Kai Yu, Zhaoming Wang, Qizhai Li, Sholom Wacholder, David J. Hunter, Robert N. Hoover, Stephen Chanock, and Gilles Thomas PLoS One 3(7):2551 (2008)
Testing logistic regression coefficients with clustered data and few positive outcomes Sally Hunsberger, Ed Korn, and Barry Graubard. Statistics in Medicine 27(8):1305-24 (2008)

Host Control of Malaria Infections: Constraints on Immune and Erythropoeitic Response Kinetics McQueen PG, McKenzie FE PLoS Computational Biology 4(8):e1000149 (2008)
Identification of the transition states in the inversion of 1, 4-benzodiazepines with the Ab Initio Replica Path Method Yong-Sok Lee, Victor W. Pike, and Milan Hodoscek. J. Phys. Chem A 112:1604-1611 (2008)
A frailty mixture cure model with application to hospital readmission cata Yu, B. Biometrical J. 50(3):386-94 (2008)
Efficient Approximation of P-value of the Maximum of Correlated Tests, with Applications to Genome-Wide Association Studies. Li Q.Z., Zheng G., Li Z.H. and Yu K. Annals of Human Genetics 72(3):397-406 (2008)
Probing potential binding modes of the p53 tetramer to DNA based on the symmetries encoded in p53 response elements Ma B, Levine AJ. Nucleic Acids Research 35(22):7733-7747 (2008)
Improved Classifier for Computer-aided Polyp Detection in CT Colonography by Nonlinear Dimensionality Reduction Shijun Wang, Jianhua Yao and Ronald M. Summers Med. Phys. 35(4):1377-86 (2008)

β2-microglobulin amyloid fragment organization and morphology and its comparison to Aβ suggests that amyloid aggregation pathways are sequence specific Zheng J, Jang H, Nussinov R. Biochemistry. Feb 26;47(8):2497-2509 (2008)
Morphology of Ion Clusters in Aqueous Electrolytes SA Hassan. Phys. Rev. E 77:03151 (2008)
Involvement of the second extracellular loop and transmembrane residues of CCR5 in inhibitor binding and HIV-1 fusion: insights into the mechanism of allosteric inhibition Maeda K, Das D, Yin PD, Tsuchiya K, Ogata-Aoki H, Nakata H, Norman RB, Hackney LA, Takaoka Y, Mitsuya H. J. Mol. Biol. 381:956-974 (2008)
Are Current Molecular Dynamics Force Fields too Helical? Robert B Best, Nicolae-Viorel Buchete and Gerhard Hummer Biophysical Letters 95(1):L07-9 (2008)
Concentration and crowding effects on protein stability from a coarse-grained model J. K. Cheung, V. K. Shen, J. R. Errington, and T. M. Truskett. in Statistical Mechanics of Cellular System, MH Zaman ed, Cambridge University Press. (2008)
Heritability of brain morphology related to schizophrenia: a large-scale automated magnetic resonance imaging segmentation study Goldman AL, Pezawas L, Mattay VS, Fischl B, Verchinski BA, Zoltick B, Weinberger DR, Meyer-Lindenberg A. Biol. Psychiatry 63(5):475-83 (2008)

Models of the Structure and Gating Mechanisms of the Pore Domain of the NaChBac Ion Channel Yinon Shafrir, Stewart R Durell and H. Robert Guy Biophys. J. 95(8):3650-62 (2008)
NIST Computational Chemistry Comparison and Benchmark Database Some of the calculations in the CCBD were performed by Russell Johnson on the Biowulf cluster. (2008)
Modeling Longitudinal Biomarker Data from Multiple Assays that Have Different Known Detection Limits Paul S. Albert Biometrics 64:527-537 (2008)
Application of 1-Aminocyclohexane Carboxylic Acid to Protein Nanostructure Computer Design. Rodriguez-Ropero F, Zanuy D, Casanovas J, Nussinov R, Aleman C. J Chem Inf Model. 48(2):333-43 (2008)
Calcium-dependent inactivation terminates calcium release in skeletal muscle of amphibians Eduardo Rios, Jingsong Zhou, Gustavo Brum, Bradley S. Launikonis, and Michael D. Stern. J. Gen. Physiol. 131(4):335-48 (2008)
Classification and 3D averaging with missing wedge correction in biological electron tomography A. Bartesaghi, P. Sprechmann, J. Liu, G. Randall, G. Sapiro and S. Subramaniam J. Struct. Biol. 162(3):436-450 (2008)

Detection of co-eluted peptides using database search methods Gelio Alves, Aleksey Y Ogurtsov, Siwei Kwok, Wells W Wu, Guanghui Wang, Rong-Fong Shen, and Yi-Kuo Yu Biol. Direct. 3:27 (2008)
Coarse Master Equations for Peptide Folding Dynamics N.V. Buchete and G. Hummer. J. Phys. Chem. B 112(19):6057-69 (2008)
Interfacial polar interactions affect gramicidin channel kinetics Rostovtseva, TK; Petrache, HI; Kazemi, N; Hassanzadeh, E; Bezrukov, SM; Biophys. J., DOI://10.1529/biophysj.107.120261 (2008)
Effective approaches for the production of heterologous proteins using the Thermococcus kodakaraensis-based translation system Takashi Endoha, Tamotsu Kanaia and Tadayuki Imanaka J. Biotech. 133(2):177-182 (2008)
Identification of the Active Sites of Biomolecules I: Methyl-alpha-mannopyranoside and Fe(III) Orkid Coskuner, Denis E. Bergeron, Luis Rincon, Jeffrey W. Hudgens, Carlos A. Gonzalez J. Phys. Chem. A 112(3):2940-2947 (2008)
Metabolic engineering of Escherichia coli for biosynthesis of hyaluronic acid Huimin Yua and Gregory Stephanopoulos Metabolic Engg. 10(1):24-32 (2008)

New structures help the modeling of toxic amyloidβ ion channels Jang H, Zheng J, Lal R, Nussinov R. Trends Biochem Sci. Feb;33(2):91-100 (2008)
Peptide folding kinetics from replica exchange molecular dynamics Nicolae-Viorel Buchete and Gerhard Hummer Phys. Rev. E 77:030902 (2008)
Structure and dynamics of Helix-0 of the N-BAR domain in Lipid Micelles and Bilayers Christian Löw, Ulrich Weininger, Hwankyu Lee, Kristian Schweimer, Ines Neundorf, Annette G. Beck-Sickinger, Richard W. Pastor and Jochen Balbach Biophys. J. 95(9):4315-23 (2008)
Reactions of Glyceraldehyde 3-Phosphate Dehydrogenase Sulfhydryl Groups with Bis-Electrophiles Produce DNA-Protein Cross-Links but Not Mutations Elisabeth M. Loecken and F. Peter Guengerich Chem. Res. Toxicol. 21(2):453-358 (2008)

2007 (82 papers)

Validating Pareto optimal operation parameters of polyp detection algorithms for CT colonography Jiang Li ; Adam Huang ; Nicholas Petrick ; Jianhua Yao ; Ronald M. Summers Proc. SPIE 6514, Medical Imaging 2007, doi:10.1117/12.707965 (2007)
Multiple comparisons distortions of parameter estimates Jeffries, NO. Biostatistics 8(2):500-4 (2007)

Engineering Metal Complexes of Chiral Pentaazacrowns as Privileged Reverse-turn Scaffolds. Y Che, Bernard Brooks, Dennis P Riley, Andrea JH Reaka, Garland R Marshall. Chemical Biology & Drug Design 69 (2) : 99-110 (2007)
RAId_DbS: Peptide identification using database searches with realistic statistics Alves G, Ogurtsov AY, Yu YK. Biol. Direct. 2:25 (2007)
Cysteine-cysteine contact preference leads to target-focusing in protein folding Sardiu ME, Cheung MS, Yu YK. Biophys. J. 93(3):938-51 (2007)
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project The ENCODE Project Consortium Nature 447:799-816 (2007)
The structure of receptor-associated protein (RAP) Donghan Lee, Joseph D. Walsh, Molly Migliorini, Ping Yu Tao Cai, Charles D. Schwieters, Susan Krueger, Dudley K. Strickland, and Yun-Xing Wang. Protein Science 16:1628-1640 (2007)
Accounting for Variability in Sample Size Estimation with Applications to Nonadherence and Estimation of Variance and Effect Size Fay, MP, Halloran, ME, Follmann, DA. Biometrics 63(2): 465-474 (2007)

Modeling the Alzheimer A β 17-42 Fibril Architecture: Tight Intermolecular Sheet-Sheet Association and Intramolecular Hydrated Cavities Zheng J, Jang H, Ma B, Tsai CJ, Nussinov R. Biophys. J. 93(9):3046-57 (2007)
Molecular and functional analyses of a novel class I secretory nuclease from the human pathogen, Leishmania donovani Joshi MB, Dwyer DM. J. Biol. Chem. 282(13):10079-95 (2007)
Induction of Epitope-Specific Neutralizing Antibodies against West Nile Virus Theodore Oliphant, Grant E. Nybakken, S. Kyle Austin, Qing Xu, Jonathan Bramson, Mark Loeb, Mark Throsby, Daved H. Fremont, Theodore C. Pierson, and Michael S. Diamond J. Virol. 81(21):11828-11839 (2007)
Ab Initio Modeling of Glycosyl Torsions and Anomeric Effects in a Model Carbohydrate: 2-Ethoxy Tetrahydropyran H. Lee Woodcock, Damian Moran, Richard W. Pastor, Alexander D. MacKerell, Jr. and Bernard R. Brooks Biophys. J. 93:1-10 (2007)
Analysis of failure time data with multilevel clustering, with application to the child vitamin a intervention trial in Nepal Shih JH, Lu SE. Biometrics 63(3):673-80 (2007)
Liquid-structure forces and electrostatic modulation of biomolecular interactions in solution SA Hassan. J. Phys. Chem B 111(1):227-41 (2007)
Natural resonance structures and aromaticity of the nucleobases Guangyu Sun & Marc Nicklaus. Theoretical Chemistry Accounts: Theory, 117(2): 323-332 (2007)
Understanding the structural and functional differences between mouse thyrotropin-releasing hormone receptors 1 and 2 Francesca Deflorian, Stanislav Engel, Anny-Odile Colson, Bruce M. Raaka, Marvin C. Gershengorn, Stefano Costanzi Proteins: Structure, Function and Bioinf 71(2):783 - 794 (2007)
Stability of Tubular Structures Based on β-Helical Proteins: Self-Assembled versus Polymerized Nanoconstructs and Wild-Type versus Mutated Sequences David Zanuy, Francisco Rodríguez-Ropero, Nurit Haspel, Jie Zheng, Ruth Nussinov, and Carlos Alem´n BIomacromolecules 8(10):3135-3146 (2007)
N-Nitrosation of amines by NO2 and NO: A theoretical study Yi-Lei Zhao, Stephen L. Garrison, Carlos Gonzalez, William David Thweatt, and Manuel Marquez J. Phys. Chem. A 111(11):2200-2205 (2007)
Exploring SCC-DFTB Paths for Mapping QM/MM Reaction Mechanisms H. Lee Woodcock, Milan Hodošček, and Bernard R. Brooks J. Phys. Chem A 111(26):5720-5728 (2007)
Comparative Study of the Effect of Tail Corrections on Surface Tension Determined by Molecular Simulation V. K. Shen, R. D. Mountain, and J. R. Errington. J. Phys. Chem B 111:6198 (2007)

A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release. Matarin M, Brown WM, Scholz S, Simon-Sanchez J, Fung HC, Hernandez D, Gibbs JR, De Vrieze FW, Crews C, Britton A, Langefeld CD, Brott TG, Brown RD Jr, Worrall BB, Frankel M, Silliman S, Case LD, Singleton A, Hardy JA, Rich SS, Meschia JF. Lancet Neurol. 6(5):414-20 (2007)
A physical picture of atomic motions within the Dickerson DNA dodecamer in solution derived from joint ensemble refinement against NMR and large-angle X-ray scattering data. Schwieters CD, Clore GM. Biochemistry 46(5):1152-66 (2007)
Sugar binding in lactose permease: anomeric state of a disaccharide influences binding structure. Klauda JB, Brooks BR. J Mol Biol. 367(5):1523-34 (2007)
Using Pareto fronts to evaluate polyp detection algorithms for CT colonography Adam Huang ; Jiang Li ; Ronald M. Summers ; Nicholas Petrick ; Amy K. Hara Medical Imaging: Computer-Aided Diagnosis, doi:10.1117/12.709426 (2007)
Spiral structure of Escherichia coli HUαβ provides foundation for DNA supercoiling Fusheng Guo and Sankar Adhya PNAS 104:4309-4314 (2007)
Two-sample Comparison Based on Prediction Error, with Applications to Candidate Gene Association Studies K. Yu, R. Martin, N. Rothman, T. Zheng, Q. Lan. Annals of Human Genetics 71 (1) :107- 118 (2007)
Preferred conformation of the glycosidic linkage of methyl-beta-mannose Coskuner O. J. Chem. Phys 127(1):015101 (2007)
Structure and Dynamics of Parallel β-Sheets, Hydrophobic Core, and Loops in Alzheimer's A β Fibrils Buchete NV, Hummer G. Biophys. J. 92(9):3032-9 (2007)
Molecular dynamics simulation of the P2Y 14 receptor. Ligand docking and identification of a putative binding site of the distal hexose moiety Ivanov, A. A.; Fricks, I; Harden, T. K.; Jacobson, K. A. Bioorg. Med. Chem. Lett. 17:761-766 (2007)
Calculation of the Free Energy and Cooperativity of Protein Folding Kentsis A, Gindin T, Mezei M, Osman R. PLoS One 2:e446 (2007)
Coarse-grained strategy for modeling protein stability in concentrated solutions. III: directional protein interactions J. K. Cheung, V. K. Shen, J. R. Errington, and T. M. Truskett. Biophys. J. 92:4316 (2007)
Context-specific amino acid substitution matrices and their use in the detection of protein homologs Goonesekere NC, Lee B. Proteins 71(2):910-919 (2007)
The Origin of Quantal Size Variation: Vesicular Glutamate Concentration Plays a Significant Role Xin-Sheng Wu, Lei Xue, Raja Mohan, Kenneth Paradiso, Kevin D. Gillis, and Ling-Gang Wu. J. Neurosc. 27(11):3046-3056 (2007)
Challenges in Projecting Clustering Results Across Gene Expression-Profiling Datasets Lara Lusa, Lisa M. McShane, James F. Reid, Loris De Cecco, Federico Ambrogi, Elia Biganzoli, Manuela Gariboldi, Marco A. Pierotti. J. National Cancer Institute 99(22): 1715-1723 (2007)
In Situ Monitoring of Hafnium Oxide Atomic Layer Deposition J.E. Maslar, W.S. Hurst, D.R. Burgess, Jr., W.A. Kimes, N.V. Nguyen, and E.F. Moore Frontiers of Char. and Metr. for Nanoelectrics (2007)
The bootstrap variance of the square of a sample mean Dodd, LE and Korn, EL. The American Statistician. 1(2):127-131 (2007)
qPrimerDepot: a primer database for quantitative real time PCR Wenwu Cui, Dennis D. Taub and Kevin Gardner Nucleic Acids Research 35:D805-D809 (2007)
Probes for Narcotic Receptor Mediated Phenomena. 34. Synthesis and Structure-Activity Relationships of a Potent μ-Agonist δ-Antagonist and an Exceedingly Potent Antinociceptive in the Enantiomeric C9-Substituted 5-(3-Hydroxyphenyl)-N-phenylethylmorphan Series Anne-C�cile Hiebel, Yong Sok Lee, Edward Bilsky, Denise Giuvelis, Jeffrey R. Deschamps, Damon A. Parrish, Mario D. Aceto, Everette L. May, Louis S. Harris, Andrew Coop, Christina M. Dersch, John S. Partilla, Richard B. Rothman, Kejun Cheng, Arthur E. Jacobson, and Kenner C. Rice J. Med. Chem. 50(16):3765-3776 (2007)
Effects of Chain Length on the Rates of CC Bond Dissociation in Linear Alkanes and Polyethylene Knyazev V J. Phys. Chem. A 111(19):3875-83 (2007)
Molecular modeling of the human P2Y2 receptor and design of a selective agonist, 2'-amino-2'-deoxy-2-thiouridine 5'-triphosphate. Ivanov AA, Ko H, Cosyn L, Maddileti S, Besada P, Fricks I, Costanzi S, Harden TK, Calenbergh SV, Jacobson KA. J. Med. Chem 50(6):1166-76 (2007)
Testing β-helix terminal coils stability by targeted substitutions with non-proteogenic amino acids: A molecular dynamics study D. Zanuy, F. Rodriguez-Ropero, R. Nussinov, C. Aleman. J. Struct. Biol. 160(2): 177-189 (2007)
Nanostructure Design Using Protein Building Blocks Enhanced by Conformationally Constrained Synthetic Residues Zheng J, Zanuy D, Haspel N, Tsai CJ, Alem C and Nussinov R. Biochemistry 46(5):1205 -1218 (2007)
Substrate-induced Conformational Changes and Dynamics of UDP-N-Acetylgalactosamine: Polypeptide N-Acetylgalactosaminyltransferase-2 Adina L Milac, Nicolae-Viorel Buchete, Timothy A Fritz, Gerhard Hummer, Lawrence A Tabak J. Mol. Biol. Oct 19;373(2):439-51 (2007)
A 2-Year Prospective Study of Human Papillomavirus Persistence among Women with a Cytological Diagnosis of Atypical Squamous Cells of Undetermined Significance or Low-Grade Squamous Intraepithelial Lesion Plummer M, Schiffman M, Castle PE, Maucort-Boulch D, Wheeler CM; ALTS Group. J Infect Dis. 195(11):1582-9 (2007)

Nimbus( BgI): An active non-LTR retrotransposon of the Schistosoma mansoni snail host Biomphalaria glabrata Raghavan N, Tettelin H, Miller A, Hostetler J, Tallon L, Knight M. Int. J. Parasitol. 37(12):1307-18 (2007)
Competition between Hydrogen Abstraction and Halogen Displacement in the Reaction of Br with CH3I, CH3Br, and CH3Cl Irikura, Karl K.; Francisco, J. S. J. Phys. Chem 111:6852-6859 (2007)
Elucidation of a C-Rich Signature Motif in Target mRNAs of RNA-Binding Protein TIAR Kim HS, Kuwano Y, Zhan M, Pullmann R Jr, Mazan-Mamczarz K, Li H, Kedersha N, Anderson P, Wilce MC, Gorospe M, Wilce JA. Mol. Cell. Biol. 27(19):6806-17 (2007)
Structural dynamics of the cooperative binding of organic molecules in the human cytochrome P450 3A4 Fishelovitch D, Hazan C, Shaik S, Wolfson HJ, Nussinov R. J Am Chem Soc. 14;129(6):1602-11 (2007)
Limits on variations in protein backbone dynamics from precise measurements of scalar couplings Vogeli B, Ying J, Grishaev A, Bax A. J. Am. Chem. Soc 129(30):9377-85 (2007)
Effects of chain length on the rates of C-C bond dissociation in linear alkanes and polyethylene Knyazev, VD J Phys Chem A, DOI://10.1021/jp066419e (2007)
Identification and regional distribution in rat brain of radiometabolites of the dopamine transporter PET radioligand [11C]PE2I Shetty HU, Zoghbi SS, Liow JS, Ichise M, Hong J, Musachio JL, Halldin C, Seidel J, Innis RB, Pike VW. Eur. J. Nucl. Med. Mol. Imaging 34(5):667-78 (2007)
Effect of a P-glycoprotein inhibitor, Cyclosporin A, on the disposition in rodent brain and blood of the 5-HT1A receptor radioligand, [11C](R)-(-)-RWAY Liow JS, Lu S, McCarron JA, Hong J, Musachio JL, Pike VW, Innis RB, Zoghbi SS. Synapse 61(2):96-105 (2007)
Electron Transport Pathway for a Streptomyces Cytochrome P450: Cytochrome P450 105D5-catalyzed fatty acid hydroxylation in Streptomyces Coelicolor A3 (2) Young-Jin Chun, Tsutomu Shimada, Raymundo Sanchez-Ponce, Martha V. Martin, Li Lei, Bin Zhao, Steven L. Kelly, Michael R. Waterman, David C. Lamb and F. Peter Guengerich J. Biol. Chem. 282:17486-17500 (2007)
A detailed transcript-level probe annotation reveals alternative splicing based microarray platform differences Joseph C Lee, David Stiles, Jun Lu, and Margaret C Cam. BMC Genomics 8: 284 (2007)
Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data. Schymick JC, Scholz SW, Fung HC, Britton A, Arepalli S, Gibbs JR, Lombardo F, Matarin M, Kasperaviciute D, Hernandez DG, Crews C, Bruijn L, Rothstein J, Mora G, Restagno G, Chio A, Singleton A, Hardy J, Traynor BJ. Lancet Neurol. 6(4):322-8 (2007)
The LeFE algorithm, embracing the complexity of gene expression in the interpretation of microarray data Eichler, GS, Reimers, M, Kane, D, Weinstein, JN. Genome Biology 8(9):R185 (2007)
Imputation Approaches for Estimating Diagnostic Accuracy for Multiple Tests from Partially Verified Designs Paul S. Albert. Biometrics 63:947-957 (2007)
An investigation of two multivariate permutation methods for controlling the false discovery proportion Edward L. Korn , Ming-Chung Li , Lisa M. McShane and Richard Simon. Statistics in Medicine 26:4428-4440 (2007)
A survey of genetic human cortical gene expression Myers AJ, Gibbs JR, Webster JA, Rohrer K, Zhao A, Marlowe L, Kaleem M, Leung D, Bryden L, Nath P, Zismann VL, Joshipura K, Huentelman MJ, Hu-Lince D, Coon KD, Craig DW, Pearson JV, Holmans P, Heward CB, Reiman EM, Stephan D, Hardy J. Nature Genetics 39(12):1494-9 (2007)
Changing the Charge Distribution of β-Helical-Based Nanostructures Can Provide the Conditions for charge transfer. Haspel N, Zanuy D, Zheng J, Aleman C, Wolfson H, Nussinov R. Biophys. J. 93(1):245-53 (2007)
Similar Binding Sites and Different Partners: Implications to Shared Proteins in Cellular Pathways Keskin O and Nussinov R. Structure 15:341-354 (2007)
Random Effects Modeling Approaches for Estimating ROC Curves from Repeated Ordinal Tests without a Gold Standard Paul Albert. Biometrics 63:593-602 (2007)

Conformational study of the protegrin-1 (PG-1) dimer interaction with lipid bilayers and its effect. Jang H, Ma B, Nussinov R. BMC Struct Biol. 2;7:21 (2007)
Molecular factors and biochemical pathways induced by febrile temperature in intraerythrocytic Plasmodium falciparum parasites Miranda S. M. Oakley, Sanjai Kumar, Vivek Anantharaman, Hong Zheng, Babita Mahajan, J. David Haynes, J. Kathleen Moch Rick Fairhurst Thomas F. McCutchan and L. Aravind. Infection and Immunity 75: 2012-2025 (2007)
Expression and Purification of Recombinant Wheat Translation Initiation Factors eIF1, eIF1A, eIF4A, eIF4B, eIF4F, eIF(iso)4F, and eIF5 Laura K. Mayberry, Michael D. Dennis, M. Leah Allen, Kelley Ruud Nitka, Patricia A. Murphy, Lara Campbell and Karen S. Browning Methods in Enzymology 430:397-408 (2007)
N-MYC Regulates Focal Adhesion Kinase Expression in Human Neuroblastoma Elizabeth A. Beierle, Angelica Trujillo, Abhilasha Nagaram, Elena V. Kurenova, Richard Finch, Xiaojie Ma, Jennifer Vella, William G. Cance and Vita M. Golubovskaya J. Biol. Chem. 282:12503-12516 (2007)
Calibrating E-values for MS2 database search methods Alves G, Ogurtsov AY, Wu WW, Wang G, Shen RF, Yu YK. Biol. Direct. 2:26 (2007)
Structural basis for p53 binding-induced DNA bending. Pan Y, Nussinov R. J Biol Chem. 5;282(1):691-9 (2007)
Confinement, entropy, and single-particle dynamics of equilibrium hard-sphere mixtures. Mittal J, Shen VK, Errington JR, Truskett TM. J Chem Phys. Oct 21;127(15):154513 (2007)
An Evaluation of Power and Type I Error of Single-Nucleotide Polymorphism Transmission/Disequilibrium-Based Statistical Methods under Different Family Structures, Missing Parental Data, and Population Stratification Kristin K. Nicodemus Augustin Luna and Yin Yao Shugart. Am. J. Hum. Genet. 80:178-185 (2007)
Density functional theory study of the clean and hydrated hematite (1[overline 1]02) surfaces Cynthia S. Lo, Kunaljeet S. Tanwar, Anne M. Chaka, and Thomas P. Trainor Phys. Rev. B 75(7):209901 (2007)
Density-functional study of magnetism in bare Au nanoclusters: Evidence of permanent size-dependent spin polarization without geometry relaxation Magyar, R. J.; Mujica, V.; Marquez, M.; Gonzalez, C. Phys. Rev. B 75(14):14421 (2007)
Optimized clonotypic analysis of T-cell receptor repertoire in immune reconstitution Packer AN, Muraro PA. Exp. Hematol. 35(3):516-21 (2007)
Neural dynamics for facial threat processing as revealed by gamma band synchronization using MEG Qian Luo, Tom Holroyd, Matthew Jones, Talma Hendler and James Blair Neuroimage 34:839-847 (2007)
Interfacing Q-Chem and CHARMM to perform QM/MM reaction path calculations. Woodcock HL 3rd, Hodoscek M, Gilbert AT, Gill PM, Schaefer HF 3rd, Brooks BR. J. Comput. Chem 28(9):1485-502 (2007)
Intrinsic Conformational Characteristics of α, α-Diphenylglycine Casanovas J, Zanuy D, Nussinov R, Aleman C. J. Org. Chem. 16;72(6):2174-81 (2007)
Identification and Biochemical Characterization of Unique Secretory Nucleases of the Human Enteric Pathogen, Entamoeba histolytica Glen C. McGugan, Jr., Manju B. Joshi, and Dennis M. Dwyer J. Biol. Chem. 282(43):31789-31802 (2007)
Use of constrained synthetic amino acids in β-helix proteins for conformational control. Zanuy D, Jimenez AI, Cativiela C, Nussinov R, Aleman C. J Phys Chem B. 111(12):3236-42 (2007)
Models of β-amyloid ion channels in the membrane suggest that channel formation in the bilayer is a Dynamic Process. Jang H, Zheng J, Nussinov R. Biophys. J. 93(6):1938-49 (2007)
Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4 Chih-chin Huang, Son N. Lam, Priyamvada Acharya, Min Tang, Shi-Hua Xiang, Syed Shahzad-ul Hussan, Robyn L. Stanfield, James Robinson, Joseph Sodroski, Ian A. Wilson, Richard Wyatt, Carole A. Bewley, Peter D. Kwong Science 317:1930-1934 (2007)

Protein recognition motifs: Design of peptidomimetics of helix surfaces Ye Che, Bernard Brooks, Garland R Marshall. Biopolymers 86(4):288 - 297 (2007)
Water dissociation in the presence of metal ions Coskuner O, Jarvis EA, Allison TC. Angew. Chem. Int. Ed 46(41): 7853 (2007)

2006 (57 papers)

Functionalized Self-Assembled Monolayers on Ultraflat Gold as Platforms for Single Molecule Force Spectroscopy and Imaging Yadavalli VK, Forbes JG, Wang K. Langmuir 22(16):6969-76 (2006)
Kinetic Study of the Gas-Phase Reaction of OH with Br2 Mikhail G. Bryukov, Barry Dellinger, and Vadim D. Knyazev J. Phys. Chem. A 110(29):9169-9174 (2006)
Surface-modulated motion switch: Capture and release of iron-sulfur protein in the cytochrome bc₁ complex Lothar Esser, Xing Gong, Shaoqing Yang, Linda Yu, Chang-An Yu and Di Xia PNAS 103(35):13045-13050 (2006)
System size and control parameter effects in reverse perturbation nonequilibrium molecular dynamics Mountain RD. J Chem Phys. 124(10):104109 (2006)

Membrane biophysics Joshua Zimmerberg. Current Biology 16:R272-R276 (2006)
De Novo Tubular Nanostructure Design Based on Self-Assembly of β-Helical Protein Motifs Nurit Haspel, David Zanuy, Carlos Alemán, Haim Wolfson and Ruth Nussinov Structure 14(7):1137-1148 (2006)
Structure by design: from single proteins and their building blocks to nanostructures Tsai C-J, Zheng J, Aleman C, Nussinov R. Trends in Biotechnoloy 24:449-454 (2006)
Constant surface tension molecular dynamics simulations of lipid bilayers with trehalose R. M. Venable, A. Skibinsky and R. W. Pastor. Molecular Simulation 32:849-855 (2006)
Effects of electric fields on proton transport through water chains S A Hassan, G Hummer and Y S Lee J. Chem. Phys 124:204510 (2006)
The MicroArray Quality Control (MAQC) project shows inter-and intraplatform reproducibility of gene expression measurements MAQC Consortium. Nature Biotechnology 24: 1151 - 1161 (2006)

Global similarity and local divergence in human and mouse gene co-expression networks. Tsaparas, P., Marino-Ramirez, L., Bodenreider, O., Koonin, E. V. and Jordan, I. K. BMC Evol Biol. 6:70 (2006)
Concordance of residual dipolar couplings, backbone order parameters and crystallographic B-factors for a small alpha/beta protein: a unified picture of high probability, fast atomic motions in proteins Clore GM, Schwieters CD. J. Mol. Biol. 355(5):879-86 (2006)
Determination of surface tension in binary mixtures using transition-matrix Monte Carlo V. K. Shen and J. R. Errington. J. Chem. Phys 124:24721 (2006)
Genes involved in DNA repair and nitrosamine metabolism and those located on chromosome 14q32 are dysregulated in nasopharyngeal carcinoma. Dodd LE, Sengupta S, Chen IH, den Boon JA, Cheng YJ, Westra W, Newton MA, Mittl BF, McShane L, Chen CJ, Ahlquist P, Hildesheim A. Cancer Epidemiol Biomarkers Prev. 15(11):2216-25 (2006)
Predicting domain-domain interactions using a parsimony approach Katia S Guimaraes, Raja Jothi, Elena Zotenko and Teresa M Przytycka. Genome Biol. 7(11): R104 (2006)
De novo peptide sequencing using exhaustive enumeration of peptide composition. Olson MT, Epstein JA, Yergey AL. J. Am. Soc. Mass. Spectrum 17(8):1041-9 (2006)

PET imaging of brain 5-HT1A receptors in rat in vivo with 18F-FCWAY and improvement by successful inhibition of radioligand defluorination with miconazole Tipre DN, Zoghbi SS, Liow JS, Green MV, Seidel J, Ichise M, Innis RB, Pike VW. J. Nucl. Med 47(2):345-53 (2006)
Chemical shift tensors of protonated base carbons in helical RNA and DNA from NMR relaxation and liquid crystal measurements. Ying J, Grishaev A, Bryce DL, Bax A. J. Am. Chem. Soc 128(35):11443-54 (2006)
Using RNA sample titrations to assess microarray platform performance and normalization techniques Shippy R et al. Nature Biotechnology 24: 1123-1131 (2006)
Interaction of Protegrin-1 with Lipid Bilayers: Membrane Thinning Effect Jang H, Ma B, Woolf TB., Nussinov R Biophysical J. 91:2848-2859 (2006)
The snail (Biomphalaria glabrata) genome project Raghavan N. and Knight M. Trends Parasitol. 22(4):148-51 (2006)
CisView: A Browser and Database of cis-regulatory Modules Predicted in the Mouse Genome Sharov A, Dudekula D, Ko MSH. DNA Research 13(3):123-34 (2006)

Using ancestry-informative markers to define populations and detect population stratification Enoch MA, Shen PH, Xu K, Hodgkinson C, Goldman D. J Psychopharmacol 20:19-26 (2006)
Augmented designs to assess immune response in vaccine trials Follmann, DA. Biometrics 62(4):1161-9 (2006)
“Similarity Trap” in Protein-Protein Interactions Could Be Carcinogenic: Simulations of p53 Core Domain Complexed with 53BP1 and BRCA1 BRCT Domains Liu J, Pan Y, Ma B, and Nussinov R. Structure 14(12):1811-21 (2006)
Engineering Cyclic Tetrapeptides Containing Chimeric Amino Acids as Preferred Reverse-Turn Scaffolds Ye Che and Garland Marshall. J. Med. Chem. 49 (1):111 -124, (2006)
Titin as a giant scaffold for integrating stress and Src homology domain 3-mediated signaling pathways Ma K, Forbes JG, Gutierrez-Cruz G, and Wang K. J. Biol Chem. 281(37):27539-56 (2006)
Development of small molecules designed to modulate protein-protein interactions Ye Che, Bernard Brooks, Garland Marshall. J. Computer-Aided Molecular Design 20(2): 109-130 (2006)

Structural Stability and Dynamics of an Amyloid-Forming Peptide GNNQQNY from the Yeast Prion Sup-35 Zheng J, Ma B, Tsai C-J, Nussinov R. Biophysical Journal 91: 824-833 (2006)
Development of a substrate-based cyclic phosphopeptide inhibitor of protein phosphatase 2Cδ, Wip1 Yamaguchi H, Durell SR, Feng H, Bai Y, Anderson CW, Appella E. Biochemistry 45(44):13193-202 (2006)
Computational Study of the Fibril Organization of Polyglutamine Repeats Reveals a Common Motif Identified in β-Helices David Zanuy, Kannan Gunasekaran, Arthur M. Lesk and Ruth Nussinov J. Mol. Biol. 358(1):330-345 (2006)
Dynamical motions of lipids and a finite size effect in simulations of bilayers Klauda JB, Brooks BR, Pastor RW. J Chem Phys. 125(14):144710 (2006)
The Stability of Monomeric Intermediates Controls Amyloid Formation: A{beta}25-35 and its N27Q Mutant Ma B, Nussinov R. Biophys. J. 90(10):3365-74 (2006)
Interpretation of Data and Identification of Information are Sine Qua Non for Modern Digital Information Services Ying He, and Mehmet Kayaalp. AMIA Annu Symp Proc. : 946 (2006)

Rat toxicogenomic study reveals analytical consistency across microarray platforms Guo, L, Edward K Lobenhofer, Charles Wang, Richard Shippy, Stephen C Harris, Lu Zhang, Nan Mei, Tao Chen, Damir Herman, Federico M Goodsaid, Patrick Hurban, Kenneth L Phillips, Jun Xu, Xutao Deng, Yongming Andrew Sun, Weida Tong, Yvonne P Dragan & Leming Shi Nature Biotechnology. 24: 1162 - 1169 (2006)
Parallel Computation and Visualization Tools for Codetermination Analysis of Multivariate Gene Expression Relations Edward B. Suh, Edward R. Dougherty, Seungchan Kim, Michael L. Bittner, Yidong Chen, Daniel E. Russ and Robert L. Martino Computational and Statistical Approaches to Genomics (2006)
SCIMS: A new algorithm for associating anticancer drug mechanisms with gene ontology categories Gabriel S. Eichler, Mark Reimers and John N. Weinstein Proc. Amer. Assoc. Cancer Res. 47:1565 (2006)
Getting practical with molecular chaperones VM Longshaw, WS Nicoll, M Botha, MH Ludewig, A Shonhai, LL Stephens and GL Blatch Protein Folding (2006)
Nucleation and cavitation of spherical, cylindrical, and slablike droplets and bubbles in small systems L. G. MacDowell, V. K. Shen, and J. R. Errington. J. Chem. Phys 125(3): 34705 (2006)
Altered HIV-1 Gag protein interactions with cyclophilin A (CypA) on the acquisition of H219Q and H219P substitutions in the CypA binding loop Gatanaga H, Das D, Suzuki Y, Yeh DD, Hussain KA, Ghosh AK, Mitsuya H. J Biol Chem. 281(2):1241-50 (2006)

Consensus features in amyloid fibrils: sheet-sheet recognition via a (polar or nonpolar) zipper structure Jie Zheng, Buyong Ma and Ruth Nussinov. Phys. Biol. 3: 1478-3975 (2006)
Impact of Cis-proline analogs on peptide conformation Ye Che, Garland R. Marshall. Biopolymers 81(5): 392 - 406 (2006)
Coarse-grained strategy for modeling protein stability in concentrated solutions. II: phase behavior. V. K. Shen, J. K. Cheung, J. R. Errington, and T. M. Truskett. Biophys. J. 90:1949 (2006)
The influence of tumor oxygenation on 18 F-FDG (Fluorine-18 Deoxyglucose) uptake: A mouse study using positron emission tomography (PET) Linda W Chan, Sebastien Hapdey, Sean English, Jurgen Seidel, Joann Carson, Anastasia L Sowers, Murali C Krishna, Michael V Green, James B Mitchell and Stephen L Bacharach. Radiation Oncology 1:3 (2006)
A Missense Mutation in the Seven-transmembrane Domain of the Human Ca2+ Receptor Converts a Negative Allosteric Modulator into a Positive Allosteric Modulator Jianxin Hu, Jiankang Jiang, Stefano Costanzi, Craig Thomas, Wu Yang, Jean H. M. Feyen, Kenneth A. Jacobson, and Allen M. Spiegel. J. Biol. Chem Vol. 281(3): 21558-21565 (2006)
The histone database: A comprehensive resource for histones and histone fold-containing proteins Marino-Ramirez, L., Hsu, B., Baxevanis, A. D. and Landsman, D Proteins 62:838-842 (2006)

Structural and Molecular Interactions of CCR5 Inhibitors with CCR5 Maeda K, Das D, Ogata-Aoki H, Nakata H, Miyakawa T, Tojo Y, Norman R, Takaoka Y, Ding J, Arnold GF, Arnold E, Mitsuya H. J Biol Chem. 281(18):12688-98 (2006)
ROC and confusion analysis of structure comparison methods identify the main causes of divergence from manual protein classification. Sam V, Tai CH, Garnier J, Gibrat JF, Lee B, Munson PJ. BMC Bioinformatics 7:206 (2006)
Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data. Fung HC, Scholz S, Matarin M, Simon-Sanchez J, Hernandez D, Britton A, Gibbs JR, Langefeld C, Stiegert ML, Schymick J, Okun MS, Mandel RJ, Fernandez HH, Foote KD, Rodriguez RL, Peckham E, De Vrieze FW, Gwinn-Hardy K, Hardy JA, Singleton A. Lancet Neurol. 5:911-916 (2006)
Multiple independent evolutionary solutions to core histone gene regulation Marino-Ramirez L, Jordan IK, Landsman D. Genome Biol. 7(12):R122 (2006)
Comparison of the Human and Worm p53 Structures Suggests a Way for Enhancing Stability Pan Y, Ma B, Levine AJ, Nussinov R. Biochemistry 45 (12):3925 -3933 (2006)
PET imaging of the dopamine transporter with 18F-FECNT: a polar radiometabolite confounds brain radioligand measurements Zoghbi SS, Shetty HU, Ichise M, Fujita M, Imaizumi M, Liow JS, Shah J, Musachio JL, Pike VW, Innis RB. J. Nucl. Med 47(3):520-7 (2006)

Appropriateness of some resampling-based inference procedures for assessing performance of prognostic classifiers derived from microarray data Lusa L, McShane LM, Radmacher MD, Shih JH, Wright GW, Simon R. Stat Med. 26(5):1102-13 (2006)
Co-evolutionary Rates of Functionally Related Yeast Genes Leonardo Marino-Ramirez, Olivier Bodenreider, Natalie Kantz and I. King Jordan Evolutionary Bioinformatics, Donald Forsdyke (ed), Springer (2006)
Comprehensive analysis of combinatorial regulation using the transcriptional regulatory network of yeast. Balaji S, Babu MM, Iyer LM, Luscombe NM, Aravind L. J. Mol. Biol. 360(1):213-27 (2006)
Automatic colonic polyp detection using multiobjective evolutionary techniques Jiang Li, Adam Huang, Jianhua Yao, and Ingmar Bitter, Nicholas Petrick, Ronald M. Summers, Perry J. Pickhardt, J. Richard Choi. In Medical Imaging 2006: Image Processing, Joseph M. Reinhardt, Josien P. W. Pluim (eds) (2006)
Backbone Conformational Preferences and Pseudorotational Ring Puckering of 1-Aminocyclopentane-1-carboxylic Acid Aleman C, Zanuy D, Casanovas J, Cativiela C, Nussinov R. J Phys Chem B 110 (42): 21264 -21271 (2006)

2005 (42 papers)

Score statistics of global sequence alignment from the energy distribution of a modified directed polymer and directed percolation problem Sardiu ME, Alves G, Yu Y-K. Phys. Rev. E 72: 061917 (2005)

Agonist-Induced Conformational Changes in Thyrotropin-Releasing Hormone Receptor Type I: Disulfide Cross-Linking and Molecular Modeling Approaches. Huang W, Osman R, Gershengorn MC. Biochemistry. 44(7):2419-2431 (2005)
CD4 binding partially locks the bridging sheet in gp120 but leaves the β2/3 strands flexible Pan Y, Ma B, Nussinov R. J Mol Biol. 350(3):514-27 (2005)
Robust accurate identification of peptides (RAId): deciphering MS2 data using a structured library search with de novo based statistics Alves G, Yu Y-K. Bioinformatics 21(19):3726-3732 (2005)
Molecular Dynamics Simulations of Alzheimer's beta-Amyloid Protofilaments Buchete NV, Tycko R, and Hummer G. Mol. Biol. 353 (4): 804-821 (2005)
PET imaging of brain with the beta-amyloid probe, [11C]6-OH-BTA-1, in a transgenic mouse model of Alzheimer's disease Toyama H, Ye D, Ichise M, Liow JS, Cai L, Jacobowitz D, Musachio JL, Hong J, Crescenzo M, Tipre D, Lu JQ, Zoghbi S, Vines DC, Seidel J, Katada K, Green MV, Pike VW, Cohen RM, Innis RB. Eur. J. Nucl. Med. Mol. Imaging 32(5):593-600 (2005)
Mutations in PIP5K3 are associated with François-Neetens mouchetée fleck corneal dystrophy Li S, Tiab L, Jiao X, Munier FL, Zografos L, Frueh BE, Sergeev Y, Smith J, Rubin B, Meallet MA, Forster RK, Hejtmancik JF, Schorderet DF. Am. J. Hum. Genet. 77(1):54-63 (2005)

Human P2Y(6) receptor: molecular modeling leads to the rational design of a novel agonist based on a unique conformational preference Costanzi S, Joshi BV, Maddileti S, Mamedova L, Gonzalez-Moa MJ, Marquez VE, Harden TK, Jacobson KA. J Med Chem. 48(26):8108-11 (2005)
In the quest for stable rescuing mutants of p53: computational mutagenesis of flexible loop L1. Pan Y, Ma B, Venkataraghavan RB, Levine AJ, Nussinov R. Biochemistry 44(5):1423-32 (2005)
Adjacent Gauche Stabilization in Linear Alkanes: Implications for Polymer Models and Conformational Analysis Jeffery B. Klauda, Richard W. Pastor, and Bernard R. Brooks J. Phys. Chem. 109(33):15684-15686 (2005)
An ab Initio Study on the Torsional Surface of Alkanes and Its Effect on Molecular Simulations of Alkanes and a DPPC Bilayer Klauda J, Brooks BR, MacKerell AD, Venable RM, Pastor RW. J. Phys. Chem. B 109 (11): 5300 -5311 (2005)
Energy landscape of amyloidogenic peptide oligomerization by parallel-tempering molecular dynamics simulation: significant role of Asn ladder. Tsai HH, Reches M, Tsai CJ, Gunasekaran K, Gazit E, Nussinov R. PNAS 102(23):8174-9 (2005)
Molecular architecture of a eukaryotic DNA transposase. Hickman AB, Perez ZN, Zhou L, Musingarimi P, Ghirlando R, Hinshaw JE, Craig NL, Dyda F. Nat Struct Mol Biol. 12: 715 - 721 (2005)

A Molecular Dynamics Study of the Response of Lipid Bilayers and Monolayers to Trehalose Skibinsky A, Venable RM, Pastor RW. Biophys. J. 89: 4111-4121 (2005)
Sequential testing for efficacy in clinical trials with non-transient effects James F. Troendle, Aiyi Liu, Chengqing Wu, Kai F. Yu. Statistics in Medicine 24(21):3239 - 3250 (2005)
Amino Acid Side Chain Interactions in the Presence of Salts Sergio A. Hassan J. Phys. Chem. 109(46):21989-21996 (2005)
Variable tick protein in two genomic groups of the relapsing fever spirochete Borrelia hermsii in western North America Porcella SF, Raffel SJ, Anderson DE Jr, Gilk SD, Bono JL, Schrumpf ME, Schwan TG. Infect. Immun. 73(10):6647-58 (2005)
Distinguishing Modes of Eukaryotic Gradient Sensing R. Skupsky, W. Losert, and R. J. Nossal Biophys. J. 89(4):2806-2823 (2005)
Bacterial 16S ribosomal DNA in house dust mite cultures Valerio CR, Murray P, Arlian LG, Slater JE. J. Allergy Clin. Immunol. 116(6):1296-300 (2005)

Accurate Determination of Leucine and Valine Side-chain Conformations using U-[15 N/13 C/2H]/[1H-(methine/methyl)-Leu/Val] Isotope Labeling, NOE Pattern Recognition, and Methine Cγ-Hγ/Cβ-Hβ Residual Dipolar Couplings: Application to the 34-kDa Enzyme IIAChitobiose Chun Tang, Junji Iwahara and G. Marius Clore J. Biomol. NMR 33(2):1573-5001 (2005)
Multiple comparisons between two groups on multiple Bernoulli outcomes while accounting for covariates. JF Troendle Stat. Med. 24(23):3581-91 (2005)
Polyproline and the “spectroscopic ruler” revisited with single-molecule fluorescence ? Schuler B, Lipman EA, Steinbach PJ, Kumke M, Eaton WA. PNAS 102(8):2754-9 (2005)
Measurement of Ribose Carbon Chemical Shift Tensors for A-form RNA by Liquid Crystal NMR Spectroscopy David L. Bryce, Alexander Grishaev, and Ad Bax. J. Am. Chem. Soc 127 (20):7387 -7396 (2005)
Molecular Dynamics Simulations of the Influenza Hemagglutinin Fusion Peptide in Micelles and Bilayers: Conformational Analysis of Peptide and Lipids Lague P, Roux B, Pastor RW. J. Mol. Biol 354: 1129-1141 (2005)
From quantum chemistry and the classical theory of polar liquids to continuum approximations in molecular mechanics calculations SA Hassan, EL Mehler. Int.Quantum Chem. 102(5): 986 - 1001 (2005)

A comparative study of amyloid fibril formation by residues 15-19 of the human calcitonin hormone: a single β-sheet model with a small hydrophobic core. Haspel N, Zanuy D, Ma B, Wolfson H, Nussinov R. J Mol Biol. 345(5):1213-27 (2005)
SspA is required for acid resistance in stationary phase by downregulation of H-NS in Escherichia coli Hansen AM, Qiu Y, Yeh N, Blattner FR, Durfee T, Jin DJ. Mol. Microbiol. 56(3):719-34 (2005)
Comparison of the protein-protein interfaces in the p53-DNA crystal structures: towards elucidation of the biological interface Ma B, Pan Y, Gunasekaran K, Venkataraghavan RB, Levine AJ, Nussinov R. PNAS 102(11):3988-93 (2005)
Comprehensive analysis of heterochromatin-and RNAi-mediated epigenetic control of the fission yeast genome Cam H, Sugiyama T, Chen ES, Chen X, Fitzgerald P, Grewal SI. Nat Genet. 37: 809 - 819 (2005)
Modelling longitudinal semicontinuous emesis volume data with serial correlation in an acupuncture clinical trial Paul S. Albert and Joannie Shen Appl. Statist. 54(4):707-720 (2005)
Ion Transport through Membrane-Spanning Nanopores Studied by Molecular Dynamics Simulations and Continuum Electrostatics Calculations Christine Peter and Gerhard Hummer. Biophys. J. 89:2222-2234 (2005)

Identification and functional outcome of mRNAs associated with RNA-binding protein TIA-1 Lopez de Silanes I, Galban S, Martindale JL, Yang X, Mazan-Mamczarz K, Indig FE, Falco G, Zhan M, Gorospe M. Mol. Cell. Biol. 25(21):9520-31 (2005)
The genome of bacteriophage K1F, a T7-like phage that has acquired the ability to replicate on K1 strains of Escherichia coli Scholl D, Merril C. J. Bacteriol. 187(24):8499-503 (2005)
Utilization of a Common Pathway for the Synthesis of High Affinity Macrocyclic Grb 2 SH 2 Domain-Binding Peptide Mimetics That Differ in the Configuration at One Ring Junction Zhen-Dan Shi, Rajeshri G. Karki, Karen M. Worthy, Lakshman K. Bindu, Marc C. Nicklaus, Robert J. Fisher, and Terrence R. Burke Jr. Chem. & Biodiversity 2:447-456 (2005)
Solution Structure of Enzyme IIAChitobiose from the N, N'-Diacetylchitobiose Branch of the Escherichia coli Phosphotransferase System ? Chun Tang, David C. Williams, Jr., Rodolfo Ghirlando, and G. Marius Clore. J. Biol. Chem 280, Issue 12:11770-11780 (2005)
Long dynamics simulations of proteins using atomistic force fields and a continuum representation of solvent effects: Calculation of structural and dynamic properties Li X, Hassan SA, Mehler EL. Proteins. 60(3):464 - 484 (2005)
Utilization of a common pathway for the synthesis of high affinity macrocyclic Grb2 SH2 domain-binding peptide mimetics that differ in the configuration at one ring junction Shi ZD, Karki RG, Worthy KM, Bindu LK, Nicklaus MC, Fisher RJ, Burke TR. Chem. & Biodivers 2:447-456 (2005)

Genome-wide assembly and analysis of alternative transcripts in mouse. Sharov AA, Dudekula DB, Ko MSH. Genome Res. 15:748-754 (2005)
Computed tomographic virtual colonoscopy computer-aided polyp detection in a screening population. Summers RM, Yao J, Pickhardt PJ, Franaszek M, Bitter I, Brickman D, Krishna V, Choi JR. Gastroenterology 129(6):1832-44 (2005)
Titin PEVK segment: charge-driven elasticity of the open and flexible polyampholyte Forbes JG, Jin AJ, Ma K, Gutierrez-Cruz G, Tsai WL, Wang K. J Muscle Res Cell Motil. 26(6-8):291-301 (2005)
Expression of estrogen receptor alpha exon-deleted mRNA variants in the human and non-human primate frontal cortex W.R. Perlman, M. Matsumoto, S. Beltaifa, T.M. Hyde, R.C. Saunders, M.J. Webster, D.R. Rubinow, J.E. Kleinman and C.S. Weickert Neuroscience 134(1):81-95 (2005)
Quantification of brain phosphodiesterase 4 in rat with (R)-[11C]Rolipram-PET Fujita M, Zoghbi SS, Crescenzo MS, Hong J, Musachio JL, Lu JQ, Liow JS, Seneca N, Tipre DN, Cropley VL, Imaizumi M, Gee AD, Seidel J, Green MV, Pike VW, Innis RB. Neuroimage 26(4):1201-10 (2005)

2004 (57 papers)

Nucleic acid transport through carbon nanotube membranes In-Chul Yeh and Gerhard Hummer. PNAS 101(33): 12177-12182 (2004)

Performance of a genetic algorithm for mass spectrometry proteomics Jeffries, NO. BMC Bioinformatics 5:180 (2004)
A Spontaneous Translational Fusion of Bacillus cereus PlcR and PapR Activates Transcription of PlcR-Dependent Genes in Bacillus anthracis via Binding with a Specific Palindromic Sequence Andrei P. Pomerantsev, Olga M. Pomerantseva, and Stephen H. Leppla Infection & Immunity 72(10):5814-5823 (2004)
Combinatorial modeling of protein folding kinetics: free energy profiles and rates Eric R. Henry and William A. Eaton Chemical Physics 307:163-185 (2004)
Dynamics of proton transfer in bacteriorhodopsin Lee YS, Krauss M. J Am Chem Soc. 126(7):2225-30 (2004)
Exploring peptide energy landscapes: A test of force fields and implicit solvent models. Steinbach PJ. Proteins 57(4):665-677 (2004)
Correcting log ratios for signal saturation in cDNA microarrays Dodd LE, Korn EL, McShane LM, Chandramouli GV, Chuang EY. Bioinformatics 20(16):2685-93 (2004)
An efficient algorithm for generating two-way contingency tables with fixed marginal totals and arbitrary mean proportions, with applications to permutation tests Craig Borkowf. Comp. Stat. and Data Analysis 44(3): 431-449 (2004)
Modulating Functional Loop Movements: The Role of Highly Conserved Residues in the Correlated Loop Motions Kannan Gunasekaran, Ruth Nussinov Chem.Bio.Chem. 5(2):224-230 (2004)
IL-15 and IL-2 reciprocally regulate expression of the chemokine receptor CX3CR1 through selective NFAT1- and NFAT2-dependent mechanisms Jana Barlic, David H. McDermott, Maya N. Merrell, Jacqueline Gonzales, Laura E. Via, and Philip M. Murphy J. Biol. Chem. 279(47):48520-48534 (2004)
Side chain interactions determine the amyloid organization: a single layer β-sheet molecular structure of the calcitonin peptide segment 15-19 David Zanuy, Nurit Haspel, Hui-Hsu (Gavin) Tsai, Buyong Ma, Kannan Gunasekaran, Haim J Wolfson and Ruth Nussinov Physical Biology 1(2):89-99 (2004)
How Much Backbone Motion in Ubiquitin Is Required To Account for Dipolar Coupling Data Measured in Multiple Alignment Media as Assessed by Independent Cross-Validation? G. Marius Clore and Charles D. Schwieters J. Am. Chem. Soc. 126(9):2923-2938 (2004)
Structure and Reaction in the Active Site of Mammalian Adenylyl Cyclase Yong-Sok Lee and Morris Krauss J. Phys. Chem. B 108(14):4508-4515 (2004)
Large-scale validation of a computer-aided polyp detection algorithm for CT colonography using cluster computing I Bitter, JE Brown, D Brickman, RM Summers Medical Imaging 2004 (2004)
Quantum Chemical Calculations and Mutational Analysis Suggest Heat Shock Protein 90 Catalyzes Trans- Cis Isomerization of Geldanamycin Lee YS, Marcu MG, Neckers L. Chem Biol. 11(7):991-8 (2004)
DBParser: web-based software for shotgun proteomic data analyses. Yang X, Dondeti V, Dezube R, Maynard DM, Geer LY, Epstein J, Chen X, Markey SP, Kowalak JA. J. Proteome Res. 3(5):1002-8 (2004)
Clustering of DNA sequences in human promoters. FitzGerald PC, Shlyakhtenko A, Mir AA, Vinson C. Genome Research 14(8):1562-74 (2004)
Amplitudes of Protein Backbone Dynamics and Correlated Motions in a Small α/β Protein: Correspondence of Dipolar Coupling and Heteronuclear Relaxation Measurements G. Marius Clore and Charles D. Schwieters Biochemistry 43(33):10678-10691 (2004)
Semirandom Sampling to Detect Differentiation-Related and Age-Related Epigenome Remodeling Valya R. Russanova, Tazuko H. Hirai and Bruce H. Howard J. Gerontology 59:1221-1233 (2004)

Three Roads to Islet Bursting: Emergent Oscillations in Coupled Phantom Bursters Charles L. Zimliki, David Mears and Arthur Sherman. Biophys. J 87:193-206 (2004)
A chlamydial type III translocated protein is tyrosine-phosphorylated at the site of entry and associated with recruitment of actin D. R. Clifton, K. A. Fields, S. S. Grieshaber, C. A. Dooley, E. R. Fischer, D. J. Mead, R. A. Carabeo, and T. Hackstadt PNAS 101(27):10166-10171 (2004)
β-Hairpin Folding Mechanism of a Nine-Residue Peptide Revealed from Molecular Dynamics Simulations in Explicit Water. Wu X and Bernard R. Brooks. Biophys. J. 86(4):1946-58 (2004)
Visualization of α-helical features in a density map constructed using 9 molecular images of the 1.8 MDa icosahedral core of pyruvate dehydrogenase Borgnia MJ, Shi D, Zhang P, Milne JL J. Struct. Biol. 147(2):136-45 (2004)
A Model of Inverse Agonist Action at Thyrotropin-Releasing Hormone Receptor Type 1: Role of a Conserved Tryptophan in Helix 6. Lu X, Huang W, Worthington S, Drabik P, Osman R, Gershengorn MC. Mol Pharmacol. 66(5):1192-200 (2004)
Simian cytomegalovirus encodes five rapidly evolving chemokine receptor homologues Sahagun-Ruiz A, Sierra-Honigmann AM, Krause P, Murphy PM. Virus Genes 28(1):71-83 (2004)
Frequency of gaps observed in a structurally aligned protein pair database suggests a simple gap penalty function Goonesekere NC, Lee B. Nucleic Acids Research 32(9):2838-43 (2004)
Absolute quantification of regional cerebral glucose utilization in mice by 18F-FDG small animal PET scanning and 2-14C-DG autoradiography Toyama H, Ichise M, Liow JS, Modell KJ, Vines DC, Esaki T, Cook M, Seidel J, Sokoloff L, Green MV, Innis RB. J. Nucl. Med 45(8):1398-405 (2004)
Identification and functional characterization of novel scorpion venom peptides with no disulfide bridge from Buthus martensii Karsch Zeng XC, Wang SX, Zhu Y, Zhu SY, Li WX. Peptides 25(2):143-50 (2004)
Rydberg-London potential for diatomic molecules and unbonded atom pairs Kevin Cahill, V. Adrian Parsegian J. Chem. Phys. 121:10839 (2004)
Statistical analysis of over-represented words in human promoter sequences. Marino-Ramirez L, Spouge JL, Kanga GC, Landsman D. Nucleic Acids Research 32(3):949-58 (2004)
Comparative analysis of apicomplexa and genomic diversity in eukaryotes. Templeton TJ, Iyer LM, Anantharaman V, Enomoto S, Abrahante JE, Subramanian GM, Hoffman SL, Abrahamsen MS, Aravind L. Genome Res. 14(9):1686-95 (2004)

Evolutionary and functional relationships within the DJ1 superfamily. Bandyopadhyay S, Cookson MR. BMC Evol Biol. 4(1):6 (2004)
Functionalization of tumor necrosis factor-alpha using phage display technique and PEGylation improves its antitumor therapeutic window Shibata H, Yoshioka Y, Ikemizu S, Kobayashi K, Yamamoto Y, Mukai Y, Okamoto T, Taniai M, Kawamura M, Abe Y, Nakagawa S, Hayakawa T, Nagata S, Yamagata Y, Mayumi T, Kamada H, Tsutsumi Y. Clin. Cancer Res. 10(24):8293-300 (2004)
Peptide sequence and amyloid formation: molecular simulations and experimental study of a human islet amyloid polypeptide fragment and its analogs Zanuy D, Porat Y, Gazit E, Nussinov R. Structure 12(3):439-55 (2004)
Synthesis and evaluation of two 18F-labeled 6-iodo-2-(4'-N,N-dimethylamino)phenylimidazo[1,2-a]pyridine derivatives as prospective radioligands for beta-amyloid in Alzheimer's disease Cai L, Chin FT, Pike VW, Toyama H, Liow JS, Zoghbi SS, Modell K, Briard E, Shetty HU, Sinclair K, Donohue S, Tipre D, Kung MP, Dagostin C, Widdowson DA, Green M, Gao W, Herman MM, Ichise M, Innis RB. J. Med. Chem 47(9):2208-18 (2004)
Mechanistic insights from a refined three-dimensional model of integrin alphaIIbbeta3 Filizola M, Hassan SA, Artoni A, Coller BS, Weinstein H. J Biol Chem 279(23):24624-30 (2004)
In silico protein design by combinatorial assembly of protein building blocks Hui-Hsu (Gavin) Tsai, Chung-Jung Tsai, Buyong Ma and Ruth Nussinov. Protein Science 13:2753-2765 (2004)

The stability and dynamics of the human calcitonin amyloid peptide DFNKF Tsai HH, Zanuy D, Haspel N, Gunasekaran K, Ma B, Tsai CJ, Nussinov R. Biophys. J. 87(1):146-58 (2004)
Mapping Development-Related and Age-Related Chromatin Remodeling by a High Throughput ChIP-HPLC Approach Valya R. Russanova, Tazuko H. Hirai, Andrei V. Tchernov and Bruce H. Howard J. Gerontology 59:1234-1243 (2004)
An Example of Slow Convergence of the Bootstrap in High Dimensions. Troendle J.F.; Korn E.L.; McShane L.M. The American Statistician 58(1): 25-29 (2004)
Discriminating the Helical Forms of Peptides by NMR and Molecular Dynamics Simulation Daron I. Freedberg, Richard M. Venable, Angelo Rossi, Thomas E. Bull, and Richard W. Pastor. J. Am. Chem. Soc 126:10478-10484 (2004)
Impact of Azaproline on Peptide Conformation Ye Che and Garland Marshall. J. Org. Chem 69 (26): 9030 -9042 (2004)
Reversible proton transfer dynamics in bacteriorhodopsin Lee YS and Krauss M. J. Mol. Stru. 700(3):243-246 (2004)

Model of full-length HIV-1 integrase complexed with viral DNA as template for anti-HIV drug design Karki RG, Tang Y, Burke TR Jr, Nicklaus MC. J Comput Aided Mol Des. 18(12):739-60 (2004)
Large-scale analysis of non-synonymous coding region single nucleotide polymorphisms Robert J Clifford, Michael N Edmonson, Cu Nguyen, Kenneth J Buetow. Bioinformatics 20(7):1006-1014 (2004)
Controlling the number of false discoveries: application to high-dimensional genomic data Korn EL, Troendle JF, McShane LM, and Simon R. Journal of Statistical Planning and Infe 124(2):379-398 (2004)
Pressure-Based Long-Range Correction for Lennard-Jones Interactions in Molecular Dynamics Simulations: Application to Alkanes and Interfaces Patrick Lague, Richard W. Pastor, Bernard R Brooks. J. Phys. Chem. B 108:363-368 (2004)
Characterization of the conformational state and flexibility of HIV-1 glycoprotein gp120 core domain Pan Y, Ma B, Keskin O, Nussinov R. J Biol Chem 16;279(29):30523-30 (2004)
Diffusion and Electrophoretic Mobility of Single-Stranded RNA from Molecular Dynamics Simulations In-Chul Yeh and Gerhard Hummer. Biophys. J. 86:681-689 (2004)
LdARF1 in Trafficking and Structural Maintenance of the trans-Golgi Cisternal Network in the Protozoan Pathogen Leishmania donovani Johanna M. Porter-Kelley, Noel J. Gerald, Juan C. Engel, Elodie Ghedin and Dennis M. Dwyer Traffic 5(11):868-883 (2004)
Insights into amyloid structural formation and assembly through computational approaches. Zanuy D, Gunasekaran K, Ma B, Tsai HH, Tsai CJ, Nussinov R. Amyloid. 11(3):143-61 (2004)
Identifying multiple changepoints in heterogeneous binary data with an application to molecular genetics Albert PS, Hunsberger SA, Hu N, Taylor PR. Biostatistics 5(4):515-529 (2004)
A cautionary note on the robustness of latent class models for estimating diagnostic error without a gold standard Albert PS, Dodd LE. Biometrics 60(2):427-35 (2004)
Evaluation of anesthesia effects on [18F]FDG uptake in mouse brain and heart using small animal PET Toyama H, Ichise M, Liow JS, Vines DC, Seneca NM, Modell KJ, Seidel J, Green MV, Innis RB. Nucl. Med. Biol. 31(2):251-6 (2004)
Release factors eRF1 and RF2: a universal mechanism controls the large conformational changes. Ma B, Nussinov R. J Biol Chem. 279(51):53875-85 (2004)
MicC, a second small-RNA regulator of Omp protein expression in Escherichia coli Chen S, Zhang A, Blyn LB, Storz G. J. Bacteriol. 186(20):6689-97 (2004)
Intermolecular Potentials of Mean Force of Amino Acid Side Chain Interactions in Aqueous Medium Hassan SA J. Phys. Chem. B. 108 (50):19501-19509 (2004)

2003 (27 papers)

Genomic analysis of bacteriophages SP6 and K1-5, an estranged subgroup of the T7 supergroup D. Scholl, J. Kieleczawa, P. Kemp, J. Rush, C. C. Richardson, C. Merril. Adhya5 and I. J. Molineux J. Mol. Biol. 335(5):1151-1171 (2003)
Synthesis and Conformational Analysis of a Locked Analogue of Carbovir Built on a Bicyclo [3.1. 0]-hex-2-enyl template. Choi Y, Sun G, George C, Nicklaus MC, Kelley JA, Marquez VE. Nucleotides Nucleic Acids. 22(12):2077-91 (2003)
Short peptide amyloid organization: stabilities and conformations of the islet amyloid peptide NFGAIL Zanuy D, Ma B, Nussinov R. Biophys. J. 84(3):1884-94 (2003)
A peptide with three hyaluronan binding motifs inhibits tumor growth and induces apoptosis Xu XM, Chen Y, Chen J, Yang S, Gao F, Underhill CB, Creswell K, Zhang L. Cancer Res. 63(18):5685-90 (2003)
Exploring the quantum mechanical/molecular mechanical replica path method: a pathway optimization of the chorismate to prephenate Claisen rearrangement catalyzed by chorismate mutase H. Lee Woodcock, Milan Hodoŝĉek, Paul Sherwood, Yong S. Lee, Henry F. Schaefer III and Bernard R. Brooks Theoretical Chemistry Accounts 109(3):140-148 (2003)
Interdependence of Backbone Flexibility, Residue Conservation, and Enzyme Function: A Case Study on β1, 4-Galactosyltransferase-I Gunasekaran K, Ma B, Ramakrishnan B, Qasba PK, Nussinov R. Biochemistry. 42(13):3674-87 (2003)
A Random Effects Transition Model For Longitudinal Binary Data With Informative Missingness Paul S Albert & Dean Follmann. Statistica Neerlandica 57 Issue 1:100-111, (2003)
Binding and Hydrolysis of Ampicillin in the Active Site of a Zinc Lactamase M. Krauss, N. Gresh, and J. Antony J. Phys. Chem B 107(5):1215-1229 (2003)
A super-linear minimization scheme for the nudged elastic band method Jhih-Wei Chu, Bernhardt L. Trout, Bernard R Brooks J. Chem. Phys. 119:12708-12717 (2003)
Changes in mumps virus gene sequence associated with variability in neurovirulent phenotype Rubin SA, Amexis G, Pletnikov M, Li Z, Vanderzanden J, Mauldin J, Sauder C, Malik T, Chumakov K, Carbone KM. J. Virol. 77(21):11616-24 (2003)
On the kinematics of protein folding Sean Cahill, Michael Cahill, Kevin Cahill. J. Comp. Chem Volume 24, Issue 11: Pages 1364-1370 (2003)
Triggering loops and enzyme function: identification of loops that trigger and modulate movements Gunasekaran K, Ma B, Nussinov R. J Mol Biol. 332(1):143-59 (2003)
Characterization of a New γ TuRC Subunit with WD Repeats Ruwanthi N. Gunawardane, Ona C. Martin, and Yixian Zheng Mol. Biol. Cell 14(3):1017-1026 (2003)
The sequence dependence of fiber organization. A comparative molecular dynamics study of the islet amyloid polypeptide segments 22-27 and 22-29. Zanuy D, Nussinov R. J Mol Biol. 329(3):565-84 (2003)
Docking of Protein-Protein Complexes on the Basis of Highly Ambiguous Intermolecular Distance Restraints Derived from 1HN/15N Chemical Shift Mapping and Backbone 15N/1H Residual Dipolar Couplings Using Conjoined Rigid Body/Torsion Angle Dynamics G. Marius Clore and Charles D. Schwieters J. Am. Chem. Soc. 125(10):2902-2912 (2003)
Modeling tumor growth with random onset Albert PS, Shih JH. Biometrics 59(4):897-906 (2003)

Molecular dynamics simulations of the unfolding of β2-microglobulin and its variants Ma B, Nussinov R. Protein Eng. 16(8):561-75 (2003)
Application of NMR, molecular simulation, and hydrodynamics to conformational analysis of trisaccharides Dixon AM, Venable R, Widmalm G, Bull TE, Pastor RW. Biopolymers 69(4):448-60 (2003)
A core-weighted fitting method for docking atomic structures into low-resolution maps: application to cryo-electron microscopy Wu X, Milne JL, Borgnia MJ, Rostapshov AV, Subramaniam S, Brooks BR. J Struct Biol. 141(1):63-76 (2003)
Lathosterolosis: an inborn error of human and murine cholesterol synthesis due to lathosterol 5-desaturase deficiency Krakowiak PA, Wassif CA, Kratz L, Cozma D, Kovárová M, Harris G, Grinberg A, Yang Y, Hunter AG, Tsokos M, Kelley RI, Porter FD. Hum. Mol. Genet. 12(13):1631-41 (2003)
Transcriptome analysis of mouse stem cells and early embryos. Sharov AA, Piao Y, Matoba R, Dudekula DB, Qian Y, VanBuren V, Falco G, Martin PR, Stagg CA, Bassey UC, Wang Y, Carter MG, Hamatani T, Aiba K, Akutsu H, Sharova L, Tanaka TS, Kimber WL, Yoshikawa T, Jaradat SA, Pantano S, Nagaraja R, Boheler KR, Taub D, Hodes RJ, Longo DL, Schlessinger D, Keller J, Klotz E, Kelsoe G, Umezawa A, Vescovi AL, Rossant J, Kunath T, Hogan BL, Curci A, D'Urso M, Kelso J, Hide W, Ko MS. PLoS Biol. 1(3):E74 (2003)
Parallel computation for coefficients of determination in the context of multivariate gene-expression analysis Edward B Suh, Daniel E Russ, Edward R Dougherty, Seungchan Kim, Michael L Bittner, Yidong Chen, Robert L. Martino in Biocomputing, editor Phillip A Laplante (2003)
The influenza A virus PB1-F2 protein targets the inner mitochondrial membrane via a predicted basic amphipathic helix that disrupts mitochondrial function Gibbs JS, Malide D, Hornung F, Bennink JR, Yewdell JW. J. Virol. 77(13):7214-24 (2003)
Direct Observation of the Folding and Unfolding of a Hairpin in Explicit Water through Computer Simulation Xiongwu Wu, Shaomeng Wang, and Bernard R. Brooks. J. Am. Chem. Soc. 124(19):5282-3 (2003)
Microarray reveals differences in both tumors and vascular specific gene expression in de novo CD5+ and CD5− diffuse large B-cell lymphomas Tohru Kobayashi, Motoko Yamaguchi, Seungchan Kim, Jun Morikawa, Shoko Ogawa, Satoshi Ueno, Edward Suh, Edward Dougherty, Ilya Shmulevich, Hiroshi Shiku, and Wei Zhang Cancer Res. 63:60 (2003)
Hydrogen bonding interactions between aldose reductase complexed with NADP(H) and inhibitor tolrestat studied by molecular dynamics simulations and binding assay Lee YS, Hodoscek M, Kador PF, Sugiyama K. Chem. Biol. Interact 143-144:307-16 (2003)
Cyclin E expression during development in Caenorhabditis elegans Brodigan TM, Liu J, Park M, Kipreos ET, Krause M. Dev. Biol. 254(1):102-115 (2003)

2002 (17 papers)

A preliminary transcriptome map of non-small cell lung cancer Fujii T, Dracheva T, Player A, Chacko S, Clifford R, Strausberg RL, Buetow K, Azumi N, Travis WD, Jen J. Cancer Res. 62(12):3340-6 (2002)
The Sm-like Hfq protein increases OxyS RNA interaction with target mRNAs Zhang A, Wassarman KM, Ortega J, Steven AC, Storz G. Mol. Cell 9(1):11-22 (2002)
Features of the NIH ATLAS Small Animal PET Scanner and Its Use with a Coaxial Small Animal Volume CT Scanner Seidel J, Vacquero JJ, Pascua J, Desco M, Johnson CA, Green M IEEE International Symposium on Biomedic, Washington, DC, 2002:TP-P1.9 (2002)
Hydrophobicity Maps of the N-Peptide Coiled Coil of HIV-1 gp41 Xavier Siebert and Gerhard Hummer Biochemistry 41(9):2956-2961 (2002)
A Latent Autoregressive Model for Longitudinal Binary Data Subject to Informative Missingness Albert, PS, Follmann, DA, Wang, SA, Suh, EB. Biometrics 58 Issue 3:631-642 (2002)
Micelle-bound conformation of a hairpin-forming peptide: combined NMR and molecular dynamics study Dixon AM, Venable RM, Pastor RW, Bull TE. Biopolymers 65(4):284-98 (2002)
Structure Activity of 3-Aryl-1, 3-diketo-Containing Compounds as HIV-1 Integrase Inhibitors1 Godwin C. G. Pais, Xuechun Zhang, Christophe Marchand, Nouri Neamati, Kiriana Cowansage, Evguenia S. Svarovskaia, Vinay K. Pathak, Yun Tang, Marc Nicklaus, Yves Pommier, and Terrence R. Burke, Jr. J. Med. Chem. 45(15):3184-3194 (2002)
Isolation and sequencing of a putative promoter region of the murine G protein beta 1 subunit (GNB1) gene Kitanaka J, Kitanaka N, Takemura M, Wang XB, Hembree CM, Goodman NL, Uhl GR. DNA Seq. 13(1):39-45 (2002)
Parametric and semiparametric approaches to testing for seasonal trend in serial count data Hunsberger S, Albert PS, Follmann DA, Suh E. Biostatistics. 3(2):289-98 (2002)
Fast-growth Thermodynamic Integration: Results for Sodium Ion Hydration G. Hummer Molecular Simulation 28:81-90 (2002)
Peptide loop-closure kinetics from microsecond molecular dynamics simulations in explicit solvent Yeh IC, Hummer G. J Am Chem Soc. 124(23):6563-8 (2002)
Ssdp proteins interact with the LIM-domain-binding protein Ldb1 to regulate development Chen L, Segal D, Hukriede NA, Podtelejnikov AV, Bayarsaihan D, Kennison JA, Ogryzko VV, Dawid IB, Westphal H. PNAS 99(22):14320-5 (2002)
Stabilities and conformations of Alzheimer's β-amyloid peptide oligomers (Aβ_16-22, Aβ_16-35, and Aβ_10-35): Sequence effects Buyong Ma and Ruth Nussinov PNAS 99(22):14126-14131 (2002)

Ixolaris, a novel recombinant tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick, Ixodes scapularis: identification of factor X and factor Xa as scaffolds for the inhibition of factor VIIa/tissue factor complex Francischetti IM, Valenzuela JG, Andersen JF, Mather TN, Ribeiro JM. Blood 99(10):3602-12 (2002)
Assembly, verification, and initial annotation of the NIA mouse 7.4 K cDNA clone set VanBuren V, Piao Y, Dudekula DB, Qian Y, Carter MG, Martin PR, Stagg CA, Bassey UC, Aiba K, Hamatani T, Kargul GJ, Luo AG, Kelso J, Hide W, Ko MS. Genome Res. 12(12):1999-2003 (2002)
Mutant deoxynucleotide carrier is associated with congenital microcephaly Rosenberg MJ, Agarwala R, Bouffard G, Davis J, Fiermonte G, Hilliard MS, Koch T, Kalikin LM, Makalowska I, Morton DH, Petty EM, Weber JL, Palmieri F, Kelley RI, Schaffer AA, Biesecker LG. Nat Genet. 32(1):175-9 (2002)
The neurogenetics of mucolipidosis type IV G. Altarescu, MD, M. Sun, MD, PhD, D. F. Moore, MD, PhD, DIC, J. A. Smith, MD, E. A. Wiggs, PhD, B. I. Solomon, MS, N. J. Patronas, MD, K. P. Frei, MD, S. Gupta, MD, C. R. Kaneski, MS, O. W. Quarrell, MD, S. A. Slaugenhaupt, PhD, E. Goldin, PhD and R. Schiffmann, MD Neurology 59:306-313 (2002)

2001 (14 papers)

Identification of fifteen novel mutations and genotype-phenotype relationship in Fabry disease Altarescu GM, Goldfarb LG, Park KY, Kaneski C, Jeffries N, Litvak S, Nagle JW, Schiffmann R. Clin. Genet. 60(1):46-51 (2001)