Papers that used NIH HPC Systems resources

Papers that used NIH HPC (Biowulf) resources

If you have published research that has made significant use of these systems, please let us know by sending email to staff@hpc.nih.gov

2020 to date (159 papers)

In vitro and in vivo identification of clinically approved drugs that modify ACE2 expression Sinha, S; Cheng, K; Schäffer, AA; Aldape, K; Schiff, E; Ruppin, E; Mol. Syst. Biol., DOI://10.15252/msb.20209628 (2020)
An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity Debruycker, V; Hutchin, A; Masureel, M et al. Nat. Struct. Mol. Biol., DOI://10.1038/s41594-020-0464-y (2020)
Laterally Resolved Small-Angle Scattering Intensity from Lipid Bilayer Simulations: An Exact and a Limited-Range Treatment Dorrell, MW; Heberle, FA; Katsaras, J; Maibaum, L; Lyman, E; Sodt, AJ; J Chem Theory Comput, DOI://10.1021/acs.jctc.0c00132 (2020)
Activation and inhibition of nonsense-mediated mRNA decay control the abundance of alternative polyadenylation products Kishor, A; Fritz, SE; Haque, N et al. Nucleic Acids Res., DOI://10.1093/nar/gkaa491 (2020)
Nanopore sequencing and the Shasta toolkit enable efficient de novo assembly of eleven human genomes Shafin, K; Pesout, T; Lorig-Roach, R et al. Nat. Biotechnol., DOI://10.1038/s41587-020-0503-6 (2020)

PLD2-PI(4,5)P2 interactions in fluid phase membranes: Structural modeling and molecular dynamics simulations Han, K; Pastor, RW; Fenollar-Ferrer, C; PLoS ONE, DOI://10.1371/journal.pone.0236201 (2020)
MEIS1 down-regulation by MYC mediates prostate cancer development through elevated HOXB13 expression and AR activity Whitlock, NC; Trostel, SY; Wilkinson, S et al. Oncogene, DOI://10.1038/s41388-020-01389-7 (2020)
PhISCS-BnB: a fast branch and bound algorithm for the perfect tumor phylogeny reconstruction problem Sadeqi Azer, E; Rashidi Mehrabadi, F; Malikić, S et al. Bioinformatics, DOI://10.1093/bioinformatics/btaa464 (2020)
Early pregnancy dyslipidemia is associated with placental DNA methylation at loci relevant for cardiometabolic diseases Ouidir, M; Zeng, X; Workalemahu, T et al. Epigenomics, DOI://10.2217/epi-2019-0293 (2020)
Integrated analysis of sialotranscriptome and sialoproteome of the brown dog tick Rhipicephalus sanguineus (s.l.): Insights into gene expression during blood feeding Tirloni, L; Lu, S; Calvo, E et al. J Proteomics, DOI://10.1016/j.jprot.2020.103899 (2020)
Structural basis of seamless excision and specific targeting by piggyBac transposase Chen, Q; Luo, W; Veach, RA; Hickman, AB; Wilson, MH; Dyda, F; Nat Commun, DOI://10.1038/s41467-020-17128-1 (2020)

Telomere-to-telomere assembly of a complete human X chromosome Miga, KH; Koren, S; Rhie, A et al. Nature, DOI://10.1038/s41586-020-2547-7 (2020)
Chromatin remodeler Ino80C acts independently of H2A.Z to evict promoter nucleosomes and stimulate transcription of highly expressed genes in yeast Qiu, H; Biernat, E; Govind, CK et al. Nucleic Acids Res., DOI://10.1093/nar/gkaa571 (2020)
Concentrations of persistent organic pollutants in maternal plasma and epigenome-wide placental DNA methylation Ouidir, M; Mendola, P; Buck Louis, GM; Kannan, K; Zhang, C; Tekola-Ayele, F; Clin Epigenetics, DOI://10.1186/s13148-020-00894-6 (2020)
Structural insight into mitochondrial β-barrel outer membrane protein biogenesis Diederichs, KA; Ni, X; Rollauer, SE et al. Nat Commun, DOI://10.1038/s41467-020-17144-1 (2020)
Epigenetic Regulation of DNA Repair Pathway Choice by MacroH2A1 Splice Variants Ensures Genome Stability Sebastian, R; Hosogane, EK; Sun, EG et al. Mol. Cell, DOI://10.1016/j.molcel.2020.06.028 (2020)
Evaluation of the Anti-Tumor Activity of the Humanized Monoclonal Antibody NEO-201 in Preclinical Models of Ovarian Cancer Zeligs, KP; Morelli, MP; David, JM et al. Front Oncol, DOI://10.3389/fonc.2020.00805 (2020)
Genome-wide association study data reveal genetic susceptibility to chronic inflammatory intestinal diseases and pancreatic ductal adenocarcinoma risk Yuan, F; Hung, RJ; Walsh, N et al. Cancer Res., DOI://10.1158/0008-5472.CAN-20-0447 (2020)
Soy protein nanofiber scaffolds for uniform maturation of hiPSC-derived retinal pigment epithelium Phelan, MA; Kruczek, K; Wilson, JP et al. Tissue Eng Part C Methods, DOI://10.1089/ten.TEC.2020.0072 (2020)
Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury Wilflingseder, J; Willi, M; Lee, HK et al. Nat Commun, DOI://10.1038/s41467-020-17205-5 (2020)
Deficiency of Adenosine Deaminase 2 (DADA2): Hidden Variants, Reduced Penetrance, and Unusual Inheritance Schnappauf, O; Zhou, Q; Moura, NS et al. J. Clin. Immunol., DOI://10.1007/s10875-020-00817-3 (2020)
Comparison of Oral Microbiota Collected Using Multiple Methods and Recommendations for New Epidemiologic Studies Yano, Y; Hua, X; Wan, Y et al. mSystems, DOI://10.1128/mSystems.00156-20 (2020)
Update of the CHARMM36 United Atom Chain Model for Hydrocarbons and Phospholipids Yu, Y; Klauda, JB; J Phys Chem B, DOI://10.1021/acs.jpcb.0c04795 (2020)

The Intriguing Effects of Substituents in the N-Phenethyl Moiety of Norhydromorphone: A Bifunctional Opioid from a Set of 'Tail Wags Dog' Experiments Wang, M; Irvin, TC; Herdman, CA et al. Molecules, DOI://10.3390/molecules25112640 (2020)
Single atom changes in newly synthesized HIV protease inhibitors reveal structural basis for extreme affinity, high genetic barrier, and adaptation to the HIV protease plasticity Bulut, H; Hattori, SI; Aoki-Ogata, H et al. Sci Rep, DOI://10.1038/s41598-020-65993-z (2020)
Inhibition stabilization is a widespread property of cortical networks Sanzeni, A; Akitake, B; Goldbach, HC; Leedy, CE; Brunel, N; Histed, MH; Elife, DOI://10.7554/eLife.54875 (2020)
Large-scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease Bandres-Ciga, S; Saez-Atienzar, S; Kim, JJ et al. Acta Neuropathol., DOI://10.1007/s00401-020-02181-3 (2020)
Sample-weighted semiparametric estimation of cause-specific cumulative risk and incidence using left- or interval-censored data from electronic health records Hyun, N; Katki, HA; Graubard, BI; Stat Med, DOI://10.1002/sim.8544 (2020)
A New Molecular-Mechanics Model for Simulations of Hydrogen Fluoride in Chemistry and Biology Orabi, EA; Faraldo-Gomez, JD; J Chem Theory Comput, DOI://10.1021/acs.jctc.0c00247 (2020)

Cotranslational folding cooperativity of contiguous domains of α-spectrin Kemp, G; Nilsson, OB; Tian, P; Best, RB; von Heijne, G; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1909683117 (2020)
Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery Guardia, CM; Tan, XF; Lian, T et al. Cell Rep, DOI://10.1016/j.celrep.2020.107837 (2020)
Ancient familial Mediterranean fever mutations in human pyrin and resistance to Yersinia pestis Park, YH; Remmers, EF; Lee, W et al. Nat. Immunol., DOI://10.1038/s41590-020-0705-6 (2020)
Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer Lin, Y; Nakatochi, M; Hosono, Y et al. Nat Commun, DOI://10.1038/s41467-020-16711-w (2020)
The genomic and epigenomic evolutionary history of papillary renal cell carcinomas Zhu, B; Poeta, ML; Costantini, M et al. Nat Commun, DOI://10.1038/s41467-020-16546-5 (2020)
The RNA-binding protein PTBP1 promotes ATPase-dependent dissociation of the RNA helicase UPF1 to protect transcripts from nonsense-mediated mRNA decay Fritz, SE; Ranganathan, S; Wang, CD; Hogg, JR; J. Biol. Chem., DOI://10.1074/jbc.RA120.013824 (2020)

fs(1)A1304 1 Is a 5' UTR Deletion of the Essential Gene small ovary in Drosophila Hammond, M; Gomez, JG; Oliver, B; Kucera, S; Benner, L; MicroPubl Biol, DOI://10.17912/micropub.biology.000246 (2020)
Activity-dependent tuning of intrinsic excitability in mouse and human neurogliaform cells Chittajallu, R; Auville, K; Mahadevan, V et al. Elife, DOI://10.7554/eLife.57571 (2020)
An improved pig reference genome sequence to enable pig genetics and genomics research Warr, A; Affara, N; Aken, B et al. Gigascience, DOI://10.1093/gigascience/giaa051 (2020)
Beware (Surprisingly Common) Left-Right Flips in Your MRI Data: An Efficient and Robust Method to Check MRI Dataset Consistency Using AFNI Glen, DR; Taylor, PA; Buchsbaum, BR; Cox, RW; Reynolds, RC; Front Neuroinform, DOI://10.3389/fninf.2020.00018 (2020)
Cell-Specific Transcriptional Responses to Heat Shock in the Mouse Utricle Epithelium Sadler, E; Ryals, MM; May, LA et al. Front Cell Neurosci, DOI://10.3389/fncel.2020.00123 (2020)
Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies Gurusamy, D; Henning, AN; Yamamoto, TN et al. Cancer Cell, DOI://10.1016/j.ccell.2020.05.004 (2020)

The genomic landscape of metastasis in treatment-naïve breast cancer models Ross, C; Szczepanek, K; Lee, M et al. PLoS Genet., DOI://10.1371/journal.pgen.1008743 (2020)
An imputation approach for fitting two-part mixed effects models for longitudinal semi-continuous data Choo-Wosoba, H; Kundu, D; Albert, PS; Stat Methods Med Res, DOI://10.1177/0962280220927720 (2020)
Variability in the analysis of a single neuroimaging dataset by many teams Botvinik-Nezer, R; Holzmeister, F; Camerer, CF et al. Nature, DOI://10.1038/s41586-020-2314-9 (2020)
Common genetic susceptibility loci link PFAPA syndrome, Behçet's disease, and recurrent aphthous stomatitis Manthiram, K; Preite, S; Dedeoglu, F et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.2002051117 (2020)
Metastasis-specific gene expression in autochthonous and allograft mouse mammary tumor models: stratification and identification of targetable signatures Ross, C; Szczepanek, K; Lee, M et al. Mol. Cancer Res., DOI://10.1158/1541-7786.MCR-20-0046 (2020)
Layer-dependent functional connectivity methods Huber, L; Finn, ES; Chai, Y et al. Prog. Neurobiol., DOI://10.1016/j.pneurobio.2020.101835 (2020)

Dynamic morphogenesis of a pioneer axon in Drosophila and its regulation by Abl tyrosine kinase Clarke, A; McQueen, PG; Fang, HY et al. Mol. Biol. Cell, DOI://10.1091/mbc.E19-10-0563 (2020)
Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer Roper, N; Brown, AL; Wei, JS et al. Cell Rep Med, DOI://10.1016/j.xcrm.2020.100007 (2020)
Ensuring meiotic DNA break formation in the mouse pseudoautosomal region Acquaviva, L; Boekhout, M; Karasu, ME et al. Nature, DOI://10.1038/s41586-020-2327-4 (2020)
DNA methylation loci in placenta associated with birthweight and expression of genes relevant for early development and adult diseases Tekola-Ayele, F; Zeng, X; Ouidir, M et al. Clin Epigenetics, DOI://10.1186/s13148-020-00873-x (2020)
Atomistic mechanism of transmembrane helix association Domański, J; Sansom, MSP; Stansfeld, PJ; Best, RB; PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1007919 (2020)
Predicting RNA SHAPE scores with deep learning Bliss, N; Bindewald, E; Shapiro, BA; RNA Biol, DOI://10.1080/15476286.2020.1760534 (2020)

The Heterogeneity of Anxious Phenotypes: Neural Responses to Errors in Treatment-Seeking Anxious and Behaviorally Inhibited Youths Smith, AR; White, LK; Leibenluft, E et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2019.05.014 (2020)
Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker Menon, R; Otto, EA; Hoover, P et al. JCI Insight, DOI://10.1172/jci.insight.133267 (2020)
Trans-ethnic meta-analysis of genome-wide association studies identifies maternal ITPR1 as a novel locus influencing fetal growth during sensitive periods in pregnancy Tekola-Ayele, F; Zhang, C; Wu, J et al. PLoS Genet., DOI://10.1371/journal.pgen.1008747 (2020)
Plasmodium vivax and Human Hexokinases Share Similar Active Sites but Display Distinct Quaternary Architectures Srivastava, SS; Darling, JE; Suryadi, J; Morris, JC; Drew, ME; Subramaniam, S; IUCrJ, DOI://10.1107/S2052252520002456 (2020)
Genetic and epigenetic intratumor heterogeneity impacts prognosis of lung adenocarcinoma Hua, X; Zhao, W; Pesatori, AC et al. Nat Commun, DOI://10.1038/s41467-020-16295-5 (2020)
Conserved protein Pir2 ARS2 mediates gene repression through cryptic introns in lncRNAs. Thillainadesan, G; Xiao, H; Holla, S et al. Nat Commun, DOI://10.1038/s41467-020-16280-y (2020)

Patients infected with Mycobacterium africanum versus Mycobacterium tuberculosis possess distinct intestinal microbiota Namasivayam, S; Diarra, B; Diabate, S et al. PLoS Negl Trop Dis, DOI://10.1371/journal.pntd.0008230 (2020)
Assessment of Genetic Association Between Parkinson Disease and Bipolar Disorder Bandres-Ciga, S; Blauwendraat, C; Singleton, AB; JAMA Neurol, DOI://10.1001/jamaneurol.2020.0248 (2020)
Dissecting the phenotypic and functional heterogeneity of mouse inflammatory osteoclasts by the expression of Cx3cr1 Madel, MB; Ibáñez, L; Ciucci, T et al. Elife, DOI://10.7554/eLife.54493 (2020)
Characterization of the development of the mouse cochlear epithelium at the single cell level Kolla, L; Kelly, MC; Mann, ZF et al. Nat Commun, DOI://10.1038/s41467-020-16113-y (2020)
Whole exome sequencing in patients with Williams-Beuren syndrome followed by disease modeling in mice points to four novel pathways that may modify stenosis risk Parrish, PCR; Liu, D; Knutsen, RH et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddaa093 (2020)
Medin Oligomer Membrane Pore Formation: A Potential Mechanism of Vascular Dysfunction Younger, S; Jang, H; Davies, HA et al. Biophys. J., DOI://10.1016/j.bpj.2020.04.026 (2020)

Assessing established BMI variants for a role in nighttime eating behavior in robustly phenotyped Southwestern American Indians Köroğlu, Ç; Gluck, ME; Traurig, M et al. Eur J Clin Nutr, DOI://10.1038/s41430-020-0654-z (2020)
Dimensionality, information and learning in prefrontal cortex Bartolo, R; Saunders, RC; Mitz, AR; Averbeck, BB; PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1007514 (2020)
Creating 2D Occupancy Plots Using plot2DO Beati, P; Chereji, RV; Methods Mol. Biol., DOI://10.1007/978-1-0716-0301-7_5 (2020)
Haplotype-resolved genomes provide insights into structural variation and gene content in Angus and Brahman cattle Low, WY; Tearle, R; Liu, R et al. Nat Commun, DOI://10.1038/s41467-020-15848-y (2020)
Quantitative Proteomics of All 14 Renal Tubule Segments in Rat Limbutara, K; Chou, CL; Knepper, MA; J. Am. Soc. Nephrol., DOI://10.1681/ASN.2020010071 (2020)
Histone Deacetylases in Kidney Physiology and Acute Kidney Injury Hyndman, KA Semin. Nephrol., DOI://10.1016/j.semnephrol.2020.01.005 (2020)

The interdependence of mammary-specific super-enhancers and their native promoters facilitates gene activation during pregnancy Zeng, X; Lee, HK; Wang, C; Achikeh, P; Liu, C; Hennighausen, L; Exp. Mol. Med., DOI://10.1038/s12276-020-0425-x (2020)
Truncated (N)-Methanocarba Nucleosides as Partial Agonists at Mouse and Human A 3 Adenosine Receptors: Affinity Enhancement by N6-(2-Phenylethyl) Substitution Tosh, DK; Salmaso, V; Rao, H et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.0c00235 (2020)
Genome-wide Profiling Identifies DNA Methylation Signatures of Aging in Rod Photoreceptors Associated with Alterations in Energy Metabolism Corso-Díaz, X; Gentry, J; Rebernick, R et al. Cell Rep, DOI://10.1016/j.celrep.2020.107525 (2020)
Prefrontal Cortex Predicts State Switches during Reversal Learning Bartolo, R; Averbeck, BB; Neuron, DOI://10.1016/j.neuron.2020.03.024 (2020)
Phase-plate cryo-EM structure of the Widom 601 CENP-A nucleosome core particle reveals differential flexibility of the DNA ends Boopathi, R; Danev, R; Khoshouei, M et al. Nucleic Acids Res., DOI://10.1093/nar/gkaa246 (2020)
Intrinsic connections between thalamic sub-regions and the lateral prefrontal cortex are differentially impacted by acute methylphenidate Gorka, AX; Lago, TR; Balderston, N et al. Psychopharmacology (Berl.), DOI://10.1007/s00213-020-05505-z (2020)

7-Deaza-7-fluoro modification confers on 4'-cyano-nucleosides potent activity against entecavir/adefovir-resistant HBV variants and favorable safety Hayashi, S; Higashi-Kuwata, N; Das, D et al. Antiviral Res., DOI://10.1016/j.antiviral.2020.104744 (2020)
Confidence intervals for the difference between two relative risks Sampson, JN; Gail, MH; Stat Methods Med Res, DOI://10.1177/0962280220915737 (2020)
High density of unrepaired genomic ribonucleotides leads to Topoisomerase 1-mediated severe growth defects in absence of ribonucleotide reductase Cerritelli, SM; Iranzo, J; Sharma, S et al. Nucleic Acids Res., DOI://10.1093/nar/gkaa103 (2020)
Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression Farmer, CA; Gilbert, JR; Moaddel, R et al. Neuropsychopharmacology, DOI://10.1038/s41386-020-0663-6 (2020)
Investigation of the Influence of Thyroid Location on Iodine-131 S Values Yeom, YS; Villoing, D; Greenstein, N et al. Radiat Prot Dosimetry, DOI://10.1093/rpd/ncaa027 (2020)
A Probabilistic Classification Tool for Genetic Subtypes of Diffuse Large B Cell Lymphoma with Therapeutic Implications Wright, GW; Huang, DW; Phelan, JD et al. Cancer Cell, DOI://10.1016/j.ccell.2020.03.015 (2020)

Quantum chemical predictions of water-octanol partition coefficients applied to the SAMPL6 logP blind challenge Jones, MR; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-020-00286-1 (2020)
Multi-phase Boltzmann weighting: accounting for local inhomogeneity in molecular simulations of water-octanol partition coefficients in the SAMPL6 challenge Krämer, A; Hudson, PS; Jones, MR; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-020-00285-2 (2020)
Feedback inhibition and its control in an insect olfactory circuit Ray, S; Aldworth, ZN; Stopfer, MA; Elife, DOI://10.7554/eLife.53281 (2020)
Interpretation of HDX Data by Maximum-Entropy Reweighting of Simulated Structural Ensembles Bradshaw, RT; Marinelli, F; Faraldo-Gómez, JD; Forrest, LR; Biophys. J., DOI://10.1016/j.bpj.2020.02.005 (2020)
A Shared Regulatory Element Controls the Initiation of Tcf7 Expression During Early T Cell and Innate Lymphoid Cell Developments Harly, C; Kenney, D; Wang, Y et al. Front Immunol, DOI://10.3389/fimmu.2020.00470 (2020)
Idiosynchrony: From shared responses to individual differences during naturalistic neuroimaging Finn, ES; Glerean, E; Khojandi, AY et al. Neuroimage, DOI://10.1016/j.neuroimage.2020.116828 (2020)

The quaternary assembly of KRas4B with Raf-1 at the membrane Jang, H; Zhang, M; Nussinov, R; Comput Struct Biotechnol J, DOI://10.1016/j.csbj.2020.03.018 (2020)
Continuous chromosome-scale haplotypes assembled from a single interspecies F1 hybrid of yak and cattle Rice, ES; Koren, S; Rhie, A et al. Gigascience, DOI://10.1093/gigascience/giaa029 (2020)
Structures of AAA protein translocase Bcs1 suggest translocation mechanism of a folded protein Tang, WK; Borgnia, MJ; Hsu, AL et al. Nat. Struct. Mol. Biol., DOI://10.1038/s41594-020-0373-0 (2020)
Structure elucidation and absolute configuration of metabolites from the soil-derived fungus Dictyosporium digitatum using spectroscopic and computational methods Tran, TD; Wilson, BAP; Henrich, CJ et al. Phytochemistry, DOI://10.1016/j.phytochem.2020.112278 (2020)
Differential DNA Methylation in Placenta Associated With Maternal Blood Pressure During Pregnancy Workalemahu, T; Ouidir, M; Shrestha, D; Wu, J; Grantz, KL; Tekola-Ayele, F; Hypertension, DOI://10.1161/HYPERTENSIONAHA.119.14509 (2020)
Family-based exome sequencing identifies rare coding variants in age-related macular degeneration Ratnapriya, R; Acar, İE; Geerlings, MJ et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddaa057 (2020)

Next-generation sequencing of the intrahepatic antibody repertoire delineates a unique B-cell response in HBV-associated acute liver failure Chen, Z; Shen, CH; Engle, RE et al. J. Viral Hepat., DOI://10.1111/jvh.13290 (2020)
Interaction between Epithelial Sodium Channel γ-Subunit and Claudin-8 Modulates Paracellular Sodium Permeability in Renal Collecting Duct Sassi, A; Wang, Y; Chassot, A et al. J. Am. Soc. Nephrol., DOI://10.1681/ASN.2019080790 (2020)
CRISPR-Cas9/phosphoproteomics identifies multiple noncanonical targets of myosin light chain kinase Isobe, K; Raghuram, V; Krishnan, L; Chou, CL; Yang, CR; Knepper, MA; Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00431.2019 (2020)
Genotype-phenotype association and variant characterization in Diamond-Blackfan anemia caused by pathogenic variants in RPL35A Gianferante, DM; Wlodarski, MW; Atsidaftos, E et al. Haematologica, DOI://10.3324/haematol.2020.246629 (2020)
Retinal Organoids derived from hiPSCs of an AIPL1-LCA Patient Maintain Cytoarchitecture despite Reduced levels of Mutant AIPL1 Lukovic, D; Artero Castro, A; Kaya, KD et al. Sci Rep, DOI://10.1038/s41598-020-62047-2 (2020)
mTORC2/Rac1 Pathway Predisposes Cancer Aggressiveness in IDH1-Mutated Glioma Liu, Y; Lu, Y; Li, A et al. Cancers (Basel), DOI://10.3390/cancers12040787 (2020)

Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress Murai, J; Zhang, H; Pongor, L et al. Cell Rep, DOI://10.1016/j.celrep.2020.02.117 (2020)
YAP1/TAZ-TEAD transcriptional networks maintain skin homeostasis by regulating cell proliferation and limiting KLF4 activity Yuan, Y; Park, J; Feng, A et al. Nat Commun, DOI://10.1038/s41467-020-15301-0 (2020)
De novo assembly of the cattle reference genome with single-molecule sequencing Rosen, BD; Bickhart, DM; Schnabel, RD et al. Gigascience, DOI://10.1093/gigascience/giaa021 (2020)
Stylized versus voxel phantoms: a juxtaposition of organ depth distributions Griffin, KT; Cuthbert, TA; Dewji, SA; Lee, C; Phys Med Biol, DOI://10.1088/1361-6560/ab7686 (2020)
Tautomer Database: A Comprehensive Resource for Tautomerism Analyses Dhaked, DK; Guasch, L; Nicklaus, MC; J Chem Inf Model, DOI://10.1021/acs.jcim.9b01156 (2020)
Toward a Comprehensive Treatment of Tautomerism in Chemoinformatics Including in InChI V2 Dhaked, DK; Ihlenfeldt, WD; Patel, H; Delannée, V; Nicklaus, MC; J Chem Inf Model, DOI://10.1021/acs.jcim.9b01080 (2020)

Multiple testing correction overcontrasts for brain imaging Alberton, BAV; Nichols, TE; Gamba, HR; Winkler, AM; Neuroimage, DOI://10.1016/j.neuroimage.2020.116760 (2020)
Prediction of stress and drug craving ninety minutes in the future with passively collected GPS data Epstein, DH; Tyburski, M; Kowalczyk, WJ et al. NPJ Digit Med, DOI://10.1038/s41746-020-0234-6 (2020)
Analysis of DNA methylation patterns in the tumor immune microenvironment of metastatic melanoma Mitra, S; Lauss, M; Cabrita, R et al. Mol Oncol, DOI://10.1002/1878-0261.12663 (2020)
Interplay between DNA damage repair and apoptosis shapes cancer evolution through aneuploidy and microsatellite instability Auslander, N; Wolf, YI; Koonin, EV; Nat Commun, DOI://10.1038/s41467-020-15094-2 (2020)
Outcome-related signatures identified by Whole Transcriptome Sequencing of Resectable Stage III/IV Melanoma Evaluated After Starting Hu14.18-IL2 Yang, RK; Kuznetsov, IB; Ranheim, EA et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-19-3294 (2020)
Longitudinal Positron Emission Tomography of Dopamine Synthesis in Subjects with GBA1 Mutations Lopez, G; Eisenberg, DP; Gregory, MD et al. Ann. Neurol., DOI://10.1002/ana.25692 (2020)

Combining fMRI during resting state and an attention bias task in children Harrewijn, A; Abend, R; Linke, J et al. Neuroimage, DOI://10.1016/j.neuroimage.2019.116301 (2020)
Sex-biased trajectories of amygdalo-hippocampal morphology change over human development Fish, AM; Nadig, A; Seidlitz, J et al. Neuroimage, DOI://10.1016/j.neuroimage.2019.116122 (2020)
Multiple lipid binding sites determine the affinity of PH domains for phosphoinositide-containing membranes Yamamoto, E; Domanski, J; Naughton, FB et al. Sci Adv, DOI://10.1126/sciadv.aay5736 (2020)
Tick-Borne Encephalitis Virus Infection Alters the Sialome of Ixodes ricinus Ticks During the Earliest Stages of Feeding Hart, CE; Ribeiro, JM; Kazimirova, M; Thangamani, S; Front Cell Infect Microbiol, DOI://10.3389/fcimb.2020.00041 (2020)
Low-frequency parietal repetitive transcranial magnetic stimulation reduces fear and anxiety Balderston, NL; Beydler, EM; Goodwin, M et al. Transl Psychiatry, DOI://10.1038/s41398-020-0751-8 (2020)
Molecular and cellular determinants of motor asymmetry in zebrafish Horstick, EJ; Bayleyen, Y; Burgess, HA; Nat Commun, DOI://10.1038/s41467-020-14965-y (2020)

C. elegans pronuclei fuse after fertilization through a novel membrane structure Rahman, M; Chang, IY; Harned, A et al. J. Cell Biol., DOI://10.1083/jcb.201909137 (2020)
Measurement of differential chromatin interactions with absolute quantification of architecture (AQuA-HiChIP) Gryder, BE; Khan, J; Stanton, BZ; Nat Protoc, DOI://10.1038/s41596-019-0285-9 (2020)
Characterizing Adult Cochlear Supporting Cell Transcriptional Diversity Using Single-Cell RNA-Seq: Validation in the Adult Mouse and Translational Implications for the Adult Human Cochlea Hoa, M; Olszewski, R; Li, X et al. Front Mol Neurosci, DOI://10.3389/fnmol.2020.00013 (2020)
Oncogenic K-Ras4B Dimerization Enhances Downstream Mitogen-activated Protein Kinase Signaling Muratcioglu, S; Aydin, C; Odabasi, E et al. J. Mol. Biol., DOI://10.1016/j.jmb.2020.01.002 (2020)
Modeling repeated labor curves in consecutive pregnancies: Individualized prediction of labor progression from previous pregnancy data Buhule, OD; Choo-Wosoba, H; Albert, PS; Stat Med, DOI://10.1002/sim.8462 (2020)
Integrative analysis suggests cell type-specific decoding of NF-κ B dynamics Martin, EW; Pacholewska, A; Patel, H; Dashora, H; Sung, MH; Sci Signal, DOI://10.1126/scisignal.aax7195 (2020)
Distribution and evolution of the serine/aspartate racemase family in plants Uda, K; Edashige, Y; Nishimura, R et al. Phytochemistry, DOI://10.1016/j.phytochem.2019.112164 (2020)
Low Serum Insulinlike Growth Factor II Levels Correlate with High BMI in American Indian Adults Muller, YL; Hanson, RL; Mahkee, D et al. Obesity (Silver Spring), DOI://10.1002/oby.22741 (2020)
CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG Liu, Z; Zhang, X; Lei, H et al. Nat Commun, DOI://10.1038/s41467-020-14684-4 (2020)
A case report of multiple primary prostate tumors with differential drug sensitivity Wilkinson, S; Harmon, SA; Terrigino, NT et al. Nat Commun, DOI://10.1038/s41467-020-14657-7 (2020)
A resource for the detailed 3D mapping of white matter pathways in the marmoset brain Liu, C; Ye, FQ; Newman, JD et al. Nat. Neurosci., DOI://10.1038/s41593-019-0575-0 (2020)
The Glu102 mutation disrupts higher-order oligomerization of the sigma 1 receptor Abramyan, AM; Yano, H; Xu, M et al. Comput Struct Biotechnol J, DOI://10.1016/j.csbj.2019.12.012 (2020)

High-Affinity Interactions of the nSH3/cSH3 Domains of Grb2 with the C-Terminal Proline-Rich Domain of SOS1 Liao, TJ; Jang, H; Nussinov, R; Fushman, D; J. Am. Chem. Soc., DOI://10.1021/jacs.9b10710 (2020)
Placental DNA methylation changes associated with maternal prepregnancy BMI and gestational weight gain Shrestha, D; Ouidir, M; Workalemahu, T; Zeng, X; Tekola-Ayele, F; Int J Obes (Lond), DOI://10.1038/s41366-020-0546-2 (2020)
Refining genome-wide associated loci for serum uric acid in individuals with African ancestry Chen, G; Shriner, D; Doumatey, AP et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddz272 (2020)
A customizable deep learning model for nosocomial risk prediction from critical care notes with indirect supervision Goodwin, TR; Demner-Fushman, D; J Am Med Inform Assoc, DOI://10.1093/jamia/ocaa004 (2020)
Transcriptional profiling and physiological roles of Aedes aegypti spermathecal-related genes Pascini, TV; Ramalho-Ortigão, M; Ribeiro, JM; Jacobs-Lorena, M; Martins, GF; BMC Genomics, DOI://10.1186/s12864-020-6543-y (2020)
Comprehensive Transcriptome Profiling of Cryptic CBFA2T3-GLIS2 Fusion-Positive AML Defines Novel Therapeutic Options: A COG and TARGET Pediatric AML Study Smith, JL; Ries, RE; Hylkema, T et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-19-1800 (2020)

TCR Repertoires of Thymic Conventional and Regulatory T Cells: Identification and Characterization of Both Unique and Shared TCR Sequences Ko, A; Watanabe, M; Nguyen, T et al. J. Immunol., DOI://10.4049/jimmunol.1901006 (2020)
Evaluating global brain connectivity as an imaging marker for depression: influence of preprocessing strategies and placebo-controlled ketamine treatment Kraus, C; Mkrtchian, A; Kadriu, B; Nugent, AC; Zarate, CA; Evans, JW; Neuropsychopharmacology, DOI://10.1038/s41386-020-0624-0 (2020)
CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention Pugacheva, EM; Kubo, N; Loukinov, D et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1911708117 (2020)
Discovery of several thousand highly diverse circular DNA viruses Tisza, MJ; Pastrana, DV; Welch, NL et al. Elife, DOI://10.7554/eLife.51971 (2020)
Sub-millimeter fMRI reveals multiple topographical digit representations that form action maps in human motor cortex Huber, L; Finn, ES; Handwerker, DA et al. Neuroimage, DOI://10.1016/j.neuroimage.2019.116463 (2020)
Truncated tetrahedral RNA nanostructures exhibit enhanced features for delivery of RNAi substrates Zakrevsky, P; Kasprzak, WK; Heinz, WF et al. Nanoscale, DOI://10.1039/c9nr08197f (2020)

SAMPL6 logP challenge: machine learning and quantum mechanical approaches Patel, P; Kuntz, DM; Jones, MR; Brooks, BR; Wilson, AK; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-020-00287-0 (2020)
A deep learning approach for the blind logP prediction in SAMPL6 challenge Prasad, S; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-020-00292-3 (2020)
Whole Genome Sequence-Based Haplotypes Reveal a Single Origin of the 1393 Bp HBB Deletion Wang, X; Xu, JZ; Conrey, A et al. J. Med. Genet., DOI://10.1136/jmedgenet-2019-106698 (2020)
Complete Genome Sequence of Myophage Ec_Makalu_002, Which Infects Uropathogenic Escherichia coli Dhungana, G; Malla, R; Rajaure, M; Adhya, S; Microbiol Resour Announc, DOI://10.1128/MRA.01530-19 (2020)
A dual apolipoprotein C-II mimetic-apolipoprotein C-III antagonist peptide lowers plasma triglycerides Wolska, A; Lo, L; Sviridov, DO et al. Sci Transl Med, DOI://10.1126/scitranslmed.aaw7905 (2020)
Characterization of Specific Ion Effects on PI(4,5)P 2 Clustering: Molecular Dynamics Simulations and Graph-Theoretic Analysis Han, K; Gericke, A; Pastor, RW; J Phys Chem B, DOI://10.1021/acs.jpcb.9b10951 (2020)

In search of genetic factors predisposing to familial hairy cell leukemia (HCL): exome-sequencing of four multiplex HCL pedigrees Pemov, A; Pathak, A; Jones, SJ et al. Leukemia, DOI://10.1038/s41375-019-0702-7 (2020)
ABC-transporter upregulation mediates resistance to the CDK7 inhibitors THZ1 and ICEC0942 Sava, GP; Fan, H; Fisher, RA et al. Oncogene, DOI://10.1038/s41388-019-1008-y (2020)
Abl Signaling Directs Growth of a Pioneer Axon in Drosophila by Shaping the Intrinsic Fluctuations of Actin Clarke, A; McQueen, PG; Fang, HY et al. Mol. Biol. Cell, DOI://10.1091/mbc.E19-10-0564 (2020)
Information-limiting correlations in large neural populations Bartolo, R; Saunders, RC; Mitz, AR; Averbeck, BB; J. Neurosci., DOI://10.1523/JNEUROSCI.2072-19.2019 (2020)
Cytosine base editor 4 but not adenine base editor generates off-target mutations in mouse embryos Lee, HK; Smith, HE; Liu, C; Willi, M; Hennighausen, L; Commun Biol, DOI://10.1038/s42003-019-0745-3 (2020)
A Transcriptome-Wide Association Study (TWAS) Identifies Novel Candidate Susceptibility Genes for Pancreatic Cancer Zhong, J; Jermusyk, A; Wu, L et al. J. Natl. Cancer Inst., DOI://10.1093/jnci/djz246 (2020)

Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease Lalaoui, N; Boyden, SE; Oda, H et al. Nature, DOI://10.1038/s41586-019-1828-5 (2020)
Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation Di Gioia, M; Spreafico, R; Springstead, JR et al. Nat. Immunol., DOI://10.1038/s41590-019-0539-2 (2020)
Mammalian Surface Display Screening of Diverse Cystine-Dense Peptide Libraries for Difficult-to-Drug Targets Crook, ZR; Sevilla, GP; Mhyre, AJ; Olson, JM; Methods Mol. Biol., DOI://10.1007/978-1-4939-9853-1_21 (2020)
Whole Exome Sequencing of Highly Aggregated Lung Cancer Families Reveals Linked Loci for Increased Cancer Risk on Chromosomes 12q, 7p, and 4q Musolf, AM; Moiz, BA; Sun, H et al. Cancer Epidemiol. Biomarkers Prev., DOI://10.1158/1055-9965.EPI-19-0887 (2020)

2019 (418 papers)

Assessment of APOE in atypical parkinsonism syndromes Sabir, MS; Blauwendraat, C; Ahmed, S et al. Neurobiol. Dis., DOI://10.1016/j.nbd.2019.02.016 (2019)
The Genetic Architecture of Parkinson Disease in Spain: Characterizing Population-Specific Risk, Differential Haplotype Structures, and Providing Etiologic Insight Bandres-Ciga, S; Ahmed, S; Sabir, MS et al. Mov. Disord., DOI://10.1002/mds.27864 (2019)

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies Nalls, MA; Blauwendraat, C; Vallerga, CL et al. Lancet Neurol, DOI://10.1016/S1474-4422(19)30320-5 (2019)
Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice Wang, Z; Xu, X; Li, JL; Palmer, C; Maric, D; Dean, J; Nat Commun, DOI://10.1038/s41467-019-13193-3 (2019)
ARSA variants in α-synucleinopathies Makarious, MB; Diez-Fairen, M; Krohn, L et al. Brain, DOI://10.1093/brain/awz340 (2019)
A New Lineage of Cryptococcus gattii (VGV) Discovered in the Central Zambezian Miombo Woodlands Farrer, RA; Chang, M; Davis, MJ et al. mBio, DOI://10.1128/mBio.02306-19 (2019)
Dose coefficients of mesh-type ICRP reference computational phantoms for external exposures of neutrons, protons, and helium ions Yeom YS, Choi C, et al. Nuc. Engg. Tech., doi://10.1016/j.net.2019.12.020 (2019)
White Blood Cell Count and Risk of Incident Lung Cancer in the UK Biobank Wong JYY, Bassig BA et al. JNCI Cancer Spectrum, doi://10.1093/jncics/pkz102 (2019)

Cryo-EM structure of substrate-free E. coli Lon protease provides insights into the dynamics of Lon machinery Botos I, Lountos GT et al. Cur. Res. Struct. Biol. , doi://0.1016/j.crstbi.2019.10.001 (2019)
Dosimetric impact of voxel resolutions of computational human phantoms for external photon exposure Choonsik Lee, Andreu Badal, Yeon Soo Yeom, Keith T Griffin and Dayton McMillan Biomed. Phys. Engg. Exp. , doi://10.1088/2057-1976/ab2850 (2019)
Joint modelling of competing risks and current status data: an application to a spontaneous labour study Youjin Lee Mei; Cheng Wang; Katherine L. Grantz; Rajeshwari Sundaram Royal Statistical Society, doi://10.1111/rssc.12351 (2019)
Head and Neck Cancers Promote an Inflammatory Transcriptome Through Coactivation of Classic and Alternative NF-κB Pathways Yang, X; Cheng, H; Chen, J et al. Cancer Immunol Res, DOI://10.1158/2326-6066.CIR-18-0832 (2019)
Classification of GBA Variants and Their Effects in Synucleinopathies Gan-Or, Z; Alcalay, RN; Makarious, MB; Scholz, SW; Blauwendraat, C; , ; Mov. Disord., DOI://10.1002/mds.27803 (2019)
H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development Jang, Y; Broun, A; Wang, C et al. Nucleic Acids Res., DOI://10.1093/nar/gky982 (2019)

A deconvolution algorithm for multi-echo functional MRI: Multi-echo Sparse Paradigm Free Mapping Caballero-Gaudes, C; Moia, S; Panwar, P; Bandettini, PA; Gonzalez-Castillo, J; Neuroimage, DOI://10.1016/j.neuroimage.2019.116081 (2019)
A tail of two sides: Artificially doubled false positive rates in neuroimaging due to the sidedness choice with t-tests Chen, G; Cox, RW; Glen, DR; Rajendra, JK; Reynolds, RC; Taylor, PA; Hum Brain Mapp, DOI://10.1002/hbm.24399 (2019)
Association of Maternal Exposure to Persistent Organic Pollutants in Early Pregnancy With Fetal Growth Ouidir, M; Buck Louis, GM; Kanner, J et al. JAMA Pediatr, DOI://10.1001/jamapediatrics.2019.5104 (2019)
Modeling ligand docking to RNA in the design of RNA-based nanostructures Kasprzak, WK; Ahmed, NA; Shapiro, BA; Curr. Opin. Biotechnol., DOI://10.1016/j.copbio.2019.10.010 (2019)
Integrating Hi-C links with assembly graphs for chromosome-scale assembly Ghurye, J; Rhie, A; Walenz, BP et al. PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1007273 (2019)
Magnetoencephalographic Correlates of Suicidal Ideation in Major Depression Gilbert, JR; Ballard, ED; Galiano, CS; Nugent, AC; Zarate, CA; Biol Psychiatry Cogn Neurosci Neuroimaging, DOI://10.1016/j.bpsc.2019.11.011 (2019)

Single Cell and Single Nucleus RNA-Seq Reveal Cellular Heterogeneity and Homeostatic Regulatory Networks in Adult Mouse Stria Vascularis Korrapati, S; Taukulis, I; Olszewski, R et al. Front Mol Neurosci, DOI://10.3389/fnmol.2019.00316 (2019)
Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods Hu, X; Compton, JR; Legler, PM; J Vis Exp, DOI://10.3791/60421 (2019)
Anoctamin 8 Tethers Endoplasmic Reticulum and Plasma Membrane for Assembly of Ca 2+ Signaling Complexes at the ER/PM Compartment Jha, A; Chung, WY; Vachel, L et al. EMBO J., DOI://10.15252/embj.2018101452 (2019)
Single-Cell Profiling Defines Transcriptomic Signatures Specific to Tumor-Reactive versus Virus-Responsive CD4+ T Cells Magen, A; Nie, J; Ciucci, T et al. Cell Rep, DOI://10.1016/j.celrep.2019.10.131 (2019)
Transcriptome-based molecular staging of human stem cell-derived retinal organoids uncovers accelerated photoreceptor differentiation by 9-cis retinal Kaya KD, Chen HY, Brooks MJ et al Mol Vis (2019)
Novel Protease Inhibitors Containing C-5-Modified bis-Tetrahydrofuranylurethane and Aminobenzothiazole as P2 and P2' Ligands That Exert Potent Antiviral Activity against Highly Multidrug-Resistant HIV-1 with a High Genetic Barrier against the Emergence of Drug Resistance Takamatsu, Y; Aoki, M; Bulut, H et al. Antimicrob. Agents Chemother., DOI://10.1128/AAC.00372-19 (2019)

Benchmarking the Performance of Time-Dependent Density Functional Theory Methods on Biochromophores Shao, Y; Mei, Y; Sundholm, D; Kaila, VRI; J Chem Theory Comput, DOI://10.1021/acs.jctc.9b00823 (2019)
Novel Central Nervous System (CNS)-Targeting Protease Inhibitors for Drug-Resistant HIV Infection and HIV-Associated CNS Complications Amano, M; Salcedo-Gómez, PM; Yedidi, RS et al. Antimicrob. Agents Chemother., DOI://10.1128/AAC.00466-19 (2019)
HLA and autoantibodies define scleroderma subtypes and risk in African and European Americans and suggest a role for molecular mimicry Gourh, P; Safran, SA; Alexander, T et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1906593116 (2019)
Maternal fatty acid concentrations and newborn DNA methylation Robinson, SL; Mumford, SL; Guan, W et al. Am. J. Clin. Nutr., DOI://10.1093/ajcn/nqz311 (2019)
DHHC20 Palmitoyl-Transferase Reshapes the Membrane to Foster Catalysis Stix, R; Song, J; Banerjee, A; Faraldo-Gómez, JD; Biophys. J., DOI://10.1016/j.bpj.2019.11.003 (2019)
Analysis of ordered composite endpoints Follmann, D; Fay, MP; Hamasaki, T; Evans, S; Stat Med, DOI://10.1002/sim.8431 (2019)

Large-scale state-dependent membrane remodeling by a transporter protein Zhou, W; Fiorin, G; Anselmi, C et al. Elife, DOI://10.7554/eLife.50576 (2019)
CNVScope: Visually Exploring Copy Number Aberrations in Cancer Genomes Dalgleish, JL; Wang, Y; Zhu, J; Meltzer, PS; Cancer Inform, DOI://10.1177/1176935119890290 (2019)
Identification of 102 Correlations between Serum Metabolites and Habitual Diet in a Metabolomics Study of the Prostate, Lung, Colorectal, and Ovarian Cancer Trial Mazzilli, KM; McClain, KM; Lipworth, L et al. J. Nutr., DOI://10.1093/jn/nxz300 (2019)
Permeability of membranes in the liquid ordered and liquid disordered phases Ghysels, A; Krämer, A; Venable, RM et al. Nat Commun, DOI://10.1038/s41467-019-13432-7 (2019)
A Thpok-Directed Transcriptional Circuitry Promotes Bcl6 and Maf Expression to Orchestrate T Follicular Helper Differentiation Vacchio, MS; Ciucci, T; Gao, Y et al. Immunity, DOI://10.1016/j.immuni.2019.06.023 (2019)
SummaryAUC: a tool for evaluating the performance of polygenic risk prediction models in validation datasets with only summary level statistics Song, L; Liu, A; Shi, J; , ; Bioinformatics, DOI://10.1093/bioinformatics/btz176 (2019)

Accurate Prediction for Antibody Resistance of Clinical HIV-1 Isolates Rawi, R; Mall, R; Shen, CH et al. Sci Rep, DOI://10.1038/s41598-019-50635-w (2019)
Gene gain and loss push prokaryotes beyond the homologous recombination barrier and accelerate genome sequence divergence Iranzo, J; Wolf, YI; Koonin, EV; Sela, I; Nat Commun, DOI://10.1038/s41467-019-13429-2 (2019)
Mash Screen: high-throughput sequence containment estimation for genome discovery Ondov, BD; Starrett, GJ; Sappington, A et al. Genome Biol., DOI://10.1186/s13059-019-1841-x (2019)
The scale-invariant, temporal profile of neuronal avalanches in relation to cortical γ-oscillations Miller, SR; Yu, S; Plenz, D; Sci Rep, DOI://10.1038/s41598-019-52326-y (2019)
Myc controls a distinct transcriptional program in fetal thymic epithelial cells that determines thymus growth Cowan, JE; Malin, J; Zhao, Y et al. Nat Commun, DOI://10.1038/s41467-019-13465-y (2019)
Ca2+-Dependent Switch of Calmodulin Interaction Mode with Tandem IQ Motifs in the Scaffolding Protein IQGAP1 Zhang, M; Li, Z; Jang, H; Hedman, AC; Sacks, DB; Nussinov, R; Biochemistry, DOI://10.1021/acs.biochem.9b00854 (2019)

Contribution of Common Genetic Variants to Familial Aggregation of Disease and Implications for Sequencing Studies Schlafly, A; Pfeiffer, RM; Nagore, E et al. PLoS Genet., DOI://10.1371/journal.pgen.1008490 (2019)
Mechanistic link between right prefrontal cortical activity and anxious arousal revealed using transcranial magnetic stimulation in healthy subjects Balderston, NL; Beydler, EM; Roberts, C et al. Neuropsychopharmacology, DOI://10.1038/s41386-019-0583-5 (2019)
Race-specific alterations in DNA methylation among middle-aged African Americans and Whites with metabolic syndrome Chitrala, KN; Hernandez, DG; Nalls, MA et al. Epigenetics, DOI://10.1080/15592294.2019.1695340 (2019)
A3 adenosine receptor activation mechanisms: molecular dynamics analysis of inactive, active, and fully active states Ciancetta, A; Rubio, P; Lieberman, DI; Jacobson, KA; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-019-00246-4 (2019)
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls Flannick, J; Mercader, JM; Fuchsberger, C et al. Nature, DOI://10.1038/s41586-019-1231-2 (2019)
Knowing What You Know in Brain Segmentation Using Bayesian Deep Neural Networks McClure, P; Rho, N; Lee, JA et al. Front Neuroinform, DOI://10.3389/fninf.2019.00067 (2019)

Commensal microbiota drive the functional diversification of colon macrophages Kang, B; Alvarado, LJ; Kim, T et al. Mucosal Immunol, DOI://10.1038/s41385-019-0228-3 (2019)
Rotamer Jumps, Proton Exchange, and Amine Inversion Dynamics of Dimethylated Lysine Residues in Proteins Resolved by pH-Dependent 1H and 13C NMR Relaxation Dispersion Weininger, U; Modig, K; Ishida, H; Vogel, HJ; Akke, M; J Phys Chem B, DOI://10.1021/acs.jpcb.9b06408 (2019)
Single cell analysis of adult mouse skeletal muscle stem cells in homeostatic and regenerative conditions Dell'Orso, S; Juan, AH; Ko, KD et al. Development, DOI://10.1242/dev.174177 (2019)
Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle Taylor, DL; Jackson, AU; Narisu, N et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1814263116 (2019)
Multiomic Profiling Identifies cis-Regulatory Networks Underlying Human Pancreatic β Cell Identity and Function Lawlor, N; Márquez, EJ; Orchard, P et al. Cell Rep, DOI://10.1016/j.celrep.2018.12.083 (2019)
Oligonucleotide Preparation Approach for Assembly of DNA Synthons Yantsevich, AV; Shchur, VV; Usanov, SA; SLAS Technol, DOI://10.1177/2472630319850534 (2019)

Second Case of HOIP Deficiency Expands Clinical Features and Defines Inflammatory Transcriptome Regulated by LUBAC Oda, H; Beck, DB; Kuehn, HS et al. Front Immunol, DOI://10.3389/fimmu.2019.00479 (2019)
Katanin Grips the β-Tubulin Tail through an Electropositive Double Spiral to Sever Microtubules Zehr, EA; Szyk, A; Szczesna, E; Roll-Mecak, A; Dev. Cell, DOI://10.1016/j.devcel.2019.10.010 (2019)
Bilateral ureteral obstruction is rapidly accompanied by ER stress and activation of autophagic degradation of IMCD proteins including AQP2 Somparn, P; Boonkrai, C; Charngkaew, K et al. Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00113.2019 (2019)
Data augmentation using generative adversarial networks (CycleGAN) to improve generalizability in CT segmentation tasks Sandfort, V; Yan, K; Pickhardt, PJ; Summers, RM; Sci Rep, DOI://10.1038/s41598-019-52737-x (2019)
Preventing dysbiosis of the neonatal mouse intestinal microbiome protects against late-onset sepsis Singer, JR; Blosser, EG; Zindl, CL et al. Nat. Med., DOI://10.1038/s41591-019-0640-y (2019)
Splicing factor DHX15 affects tp53 and mdm2 expression via alternate splicing and promoter usage McElderry, J; Carrington, B; Bishop, K et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddz261 (2019)

Tango1 coordinates the formation of ER/Golgi docking sites to mediate secretory granule formation Reynolds, HM; Zhang, L; Tran, DT; Ten Hagen, KG; J. Biol. Chem., DOI://10.1074/jbc.RA119.011063 (2019)
Williams syndrome hemideletion and LIMK1 variation both affect dorsal stream functional connectivity Gregory, MD; Mervis, CB; Elliott, ML et al. Brain, DOI://10.1093/brain/awz323 (2019)
Reducing motion sensitivity in 3D high-resolution T2*-weighted MRI by navigator-based motion and nonlinear magnetic field correction Liu, J; van Gelderen, P; de Zwart, JA; Duyn, JH; Neuroimage, DOI://10.1016/j.neuroimage.2019.116332 (2019)
Single-Cell Transcriptome Analysis Reveals Gene Signatures Associated with T-cell Persistence Following Adoptive Cell Therapy Lu, YC; Jia, L; Zheng, Z; Tran, E; Robbins, PF; Rosenberg, SA; Cancer Immunol Res, DOI://10.1158/2326-6066.CIR-19-0299 (2019)
Over-expression of Vitreoscilla hemoglobin (VHb) and flavohemoglobin (FHb) genes greatly enhances pullulan production Xue, SJ; Jiang, H; Chen, L et al. Int. J. Biol. Macromol., DOI://10.1016/j.ijbiomac.2019.04.007 (2019)
Dose coefficients of percentile-specific computational phantoms for photon external exposures Yeom, YS; Han, H; Choi, C; Shin, B; Kim, CH; Lee, C; Radiat Environ Biophys, DOI://10.1007/s00411-019-00818-w (2019)

Characteristics of respiratory measures in young adults scanned at rest, including systematic changes and "missed" deep breaths Power, JD; Lynch, CJ; Dubin, MJ; Silver, BM; Martin, A; Jones, RM; Neuroimage, DOI://10.1016/j.neuroimage.2019.116234 (2019)
Impact of CMV Infection on Natural Killer Cell Clonal Repertoire in CMV-Naïve Rhesus Macaques Truitt, LL; Yang, D; Espinoza, DA et al. Front Immunol, DOI://10.3389/fimmu.2019.02381 (2019)
Prepontine non-giant neurons drive flexible escape behavior in zebrafish Marquart, GD; Tabor, KM; Bergeron, SA; Briggman, KL; Burgess, HA; PLoS Biol., DOI://10.1371/journal.pbio.3000480 (2019)
Approximation of Bias and Mean Squared Error in Two-sample Mendelian Randomization Analyses Deng, L; Zhang, H; Song, L; Yu, K; Biometrics, DOI://10.1111/biom.13169 (2019)
AI Meets Exascale Computing: Advancing Cancer Research With Large-Scale High Performance Computing Bhattacharya, T; Brettin, T; Doroshow, JH et al. Front Oncol, DOI://10.3389/fonc.2019.00984 (2019)
Plasmid Dissemination and Selection of a Multidrug-Resistant Klebsiella pneumoniae Strain during Transplant-Associated Antibiotic Therapy Conlan, S; Lau, AF; Deming, C et al. MBio, DOI://10.1128/mBio.00652-19 (2019)

Stereotyped transcriptomic transformation of somatosensory neurons in response to injury Nguyen, MQ; Le Pichon, CE; Ryba, N; Elife, DOI://10.7554/eLife.49679 (2019)
Cryo-EM structure of the bacterial Ton motor subcomplex ExbB-ExbD provides information on structure and stoichiometry Celia, H; Botos, I; Ni, X et al. Commun Biol, DOI://10.1038/s42003-019-0604-2 (2019)
Single-Cell RNA-seq Identifies Cell Diversity in Embryonic Salivary Glands Sekiguchi, R; Martin, D; , ; Yamada, KM; J. Dent. Res., DOI://10.1177/0022034519883888 (2019)
Embryo polarity in moth flies and mosquitoes relies on distinct old genes with localized transcript isoforms Yoon, Y; Klomp, J; Martin-Martin, I et al. Elife, DOI://10.7554/eLife.46711 (2019)
Differential Nucleosome Spacing in Neurons and Glia Clark, SC; Chereji, RV; Lee, PR; Fields, RD; Clark, DJ; Neurosci. Lett., DOI://10.1016/j.neulet.2019.134559 (2019)
Improved Retinal Organoid Differentiation by Modulating Signaling Pathways Revealed by Comparative Transcriptome Analyses with Development In Vivo Brooks, MJ; Chen, HY; Kelley, RA et al. Stem Cell Reports, DOI://10.1016/j.stemcr.2019.09.009 (2019)

Gata2 deficiency delays leukemogenesis while contributing to aggressive leukemia phenotype in Cbfb-MYH11 knockin mice Saida, S; Zhen, T; Kim, E et al. Leukemia, DOI://10.1038/s41375-019-0605-7 (2019)
Cell Type- and Sex-Dependent Transcriptome Profiles of Rat Anterior Pituitary Cells Fletcher, PA; Smiljanic, K; Maso Prévide, R et al. Front Endocrinol (Lausanne), DOI://10.3389/fendo.2019.00623 (2019)
Differences in Genome-wide DNA Methylation Profiles in Breast Milk by Race and Lactation Duration Davis Lynn, BC; Bodelon, C; Pfeiffer, RM et al. Cancer Prev Res (Phila), DOI://10.1158/1940-6207.CAPR-19-0169 (2019)
Multi-phosphorylation reaction and clustering tune Pom1 gradient mid-cell levels according to cell size Gerganova, V; Floderer, C; Archetti, A et al. Elife, DOI://10.7554/eLife.45983 (2019)
Strong dependence of the nano-bio interactions on core morphology and layer composition of ultrasmall nanostructures Hassan, SA J Chem Phys, DOI://10.1063/1.5115192 (2019)
Discovery and Development of Anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication Maeda, K; Das, D; Kobayakawa, T; Tamamura, H; Takeuchi, H; Curr Top Med Chem, DOI://10.2174/1568026619666190712204603 (2019)

Direct Derivation of Free Energies of Membrane Deformation and Other Solvent Density Variations From Enhanced Sampling Molecular Dynamics Fiorin, G; Marinelli, F; Faraldo-Gómez, JD; J Comput Chem, DOI://10.1002/jcc.26075 (2019)
Clonal tracking of erythropoiesis in rhesus macaques Fan, X; Wu, C; Truitt, LL et al. Haematologica, DOI://10.3324/haematol.2019.231811 (2019)
Molecular Classification of Epithelial Ovarian Cancer Based on Methylation Profiling: Evidence for Survival Heterogeneity Bodelon, C; Killian, JK; Sampson, JN et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-3720 (2019)
Layer-dependent activity in human prefrontal cortex during working memory Finn, ES; Huber, L; Jangraw, DC; Molfese, PJ; Bandettini, PA; Nat. Neurosci., DOI://10.1038/s41593-019-0487-z (2019)
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution Justice, AE; Karaderi, T; Highland, HM et al. Nat. Genet., DOI://10.1038/s41588-018-0334-2 (2019)
Dynamic Emergence of Mismatch Repair Deficiency Facilitates Rapid Evolution of Ceftazidime-Avibactam Resistance in Pseudomonas aeruginosa Acute Infection Khil, PP; Dulanto Chiang, A; Ho, J et al. MBio, DOI://10.1128/mBio.01822-19 (2019)

Drosophila Heterochromatin Stabilization Requires the Zinc-Finger Protein Small Ovary Benner, L; Castro, EA; Whitworth, C et al. Genetics, DOI://10.1534/genetics.119.302590 (2019)
Dual antagonist of cIAP/XIAP ASTX660 sensitizes HPV-and HPV+ head and neck cancers to TNFα, TRAIL, and radiation Therapy Xiao, R; An, Y; Ye, W et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-3802 (2019)
Generation of small molecule-binding RNA arrays and their application to fluorogen-binding RNA aptamers Henderson, CA; Rail, CA; Butt, LE; Vincent, HA; Callaghan, AJ; Methods, DOI://10.1016/j.ymeth.2019.04.021 (2019)
Gene-based association analysis of survival traits via functional regression-based mixed effect cox models for related samples Chiu, CY; Zhang, B; Wang, S et al. Genet. Epidemiol., DOI://10.1002/gepi.22254 (2019)
Molecular characterization of respiratory syncytial viruses circulating in a paediatric cohort in Amman, Jordan Trovão, NS; Khuri-Bulos, N; Tan, Y et al. Microb Genom, DOI://10.1099/mgen.0.000292 (2019)
A Novel Bromine-Containing Paroxetine Analogue Provides Mechanistic Clues for Binding Ambiguity at the Central Primary Binding Site of the Serotonin Transporter Slack, RD; Abramyan, AM; Tang, H et al. ACS Chem Neurosci, DOI://10.1021/acschemneuro.9b00375 (2019)

Low Abundance of Circulating Tumor DNA in Localized Prostate Cancer Hennigan, ST; Trostel, SY; Terrigino, NT et al. JCO Precis Oncol, DOI://10.1200/PO.19.00176 (2019)
Automated Liver Fat Quantification at Nonenhanced Abdominal CT for Population-based Steatosis Assessment Graffy, PM; Sandfort, V; Summers, RM; Pickhardt, PJ; Radiology, DOI://10.1148/radiol.2019190512 (2019)
lncRNA expression predicts mRNA abundance Pacholewska, A; Sung, MH; Epigenomics, DOI://10.2217/epi-2019-0003 (2019)
Quantitative MNase-seq accurately maps nucleosome occupancy levels Chereji, RV; Bryson, TD; Henikoff, S; Genome Biol., DOI://10.1186/s13059-019-1815-z (2019)
Synthesis and Characterization of Bodipy-FL-Cyclosporine A as a Substrate for Multidrug Resistance-Linked P-Glycoprotein (ABCB1) Sajid, A; Raju, N; Lusvarghi, S; Vahedi, S; Swenson, RE; Ambudkar, SV; Drug Metab. Dispos., DOI://10.1124/dmd.119.087734 (2019)
Accessibility of promoter DNA is not the primary determinant of chromatin-mediated gene regulation Chereji, RV; Eriksson, PR; Ocampo, J; Prajapati, HK; Clark, DJ; Genome Res., DOI://10.1101/gr.249326.119 (2019)

Structure of the primed state of the ATPase domain of chromatin remodeling factor ISWI bound to the nucleosome Chittori, S; Hong, J; Bai, Y; Subramaniam, S; Nucleic Acids Res., DOI://10.1093/nar/gkz670 (2019)
De Novo Variants in WDR37 Are Associated with Epilepsy, Colobomas, Dysmorphism, Developmental Delay, Intellectual Disability, and Cerebellar Hypoplasia Kanca, O; Andrews, JC; Lee, PT et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2019.06.014 (2019)
A Monte Carlo model for organ dose reconstruction of patients in Pencil Beam Scanning (PBS) proton therapy for epidemiologic studies of late effects Yeom, YS; Kuzmin, G; Griffin, KT et al. J Radiol Prot, DOI://10.1088/1361-6498/ab437d (2019)
NMR characterization of rearranged staurosporine aglycone analogues from the marine sponge Damiria sp Tran, TD; Cartner, LK; Bokesch, HR et al. Magn Reson Chem, DOI://10.1002/mrc.4932 (2019)
The Spodoptera frugiperda Sf9 cell line is a heterogeneous population of rhabdovirus-infected and virus-negative cells: Isolation and characterization of cell clones containing rhabdovirus X-gene variants and virus-negative cell clones Ma, H; Nandakumar, S; Bae, EH; Chin, PJ; Khan, AS; Virology, DOI://10.1016/j.virol.2019.08.001 (2019)
Genome-wide DNA methylation analysis of colorectal adenomas with and without recurrence reveals an association between cytosine-phosphate-guanine methylation and histological subtypes Fiedler, D; Hirsch, D; El Hajj, N et al. Genes Chromosomes Cancer, DOI://10.1002/gcc.22787 (2019)

The Structural Basis of the Farnesylated and Methylated KRas4B Interaction with Calmodulin Jang, H; Banerjee, A; Marcus, K et al. Structure, DOI://10.1016/j.str.2019.08.009 (2019)
Imaging the spontaneous flow of thought: Distinct periods of cognition contribute to dynamic functional connectivity during rest Gonzalez-Castillo, J; Caballero-Gaudes, C; Topolski, N; Handwerker, DA; Pereira, F; Bandettini, PA; Neuroimage, DOI://10.1016/j.neuroimage.2019.116129 (2019)
Papillomavirus can be transmitted through the blood and produce infections in blood recipients: Evidence from two animal models Cladel, NM; Jiang, P; Li, JJ et al. Emerg Microbes Infect, DOI://10.1080/22221751.2019.1637072 (2019)
Cysteinyl-tRNA Synthetase Mutations Cause a Multi-System, Recessive Disease That Includes Microcephaly, Developmental Delay, and Brittle Hair and Nails Kuo, ME; Theil, AF; Kievit, A et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2019.01.006 (2019)
Sex differences in the associations of placental epigenetic aging with fetal growth Tekola-Ayele, F; Workalemahu, T; Gorfu, G et al. Aging (Albany NY), DOI://10.18632/aging.102124 (2019)
Genome-wide association study for proliferative diabetic retinopathy in Africans Liu, C; Chen, G; Bentley, AR et al. NPJ Genom Med, DOI://10.1038/s41525-019-0094-7 (2019)

Cohesin Impedes Heterochromatin Assembly in Fission Yeast Cells Lacking Pds5 Folco, HD; McCue, A; Balachandran, V; Grewal, SIS; Genetics, DOI://10.1534/genetics.119.302256 (2019)
T-Cell Deletion of MyD88 Connects IL17 and IκBζ to RAS Oncogenesis Cataisson, C; Salcedo, R; Michalowski, AM et al. Mol. Cancer Res., DOI://10.1158/1541-7786.MCR-19-0227 (2019)
Novel pathogenic COX20 variants causing dysarthria, ataxia, and sensory neuropathy Otero, MG; Tiongson, E; Diaz, F et al. Ann Clin Transl Neurol, DOI://10.1002/acn3.661 (2019)
Glucocorticoid receptor quaternary structure drives chromatin occupancy and transcriptional outcome Paakinaho, V; Johnson, TA; Presman, DM; Hager, GL; Genome Res., DOI://10.1101/gr.244814.118 (2019)
Modulation of Target Antigen Density Improves CAR T-cell Functionality and Persistence Ramakrishna, S; Highfill, SL; Walsh, Z et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-3784 (2019)
Pathogenic TERT promoter variants in telomere diseases Gutierrez-Rodrigues, F; Donaires, FS; Pinto, A et al. Genet. Med., DOI://10.1038/s41436-018-0385-x (2019)
Epigenetic aging is accelerated in alcohol use disorder and regulated by genetic variation in APOL2 Luo, A; Jung, J; Longley, M et al. Neuropsychopharmacology, DOI://10.1038/s41386-019-0500-y (2019)
Relationship of DNA methylation to mutational changes and transcriptional organization in fusion-positive and fusion-negative rhabdomyosarcoma Sun, W; Chatterjee, B; Shern, JF et al. Int. J. Cancer, DOI://10.1002/ijc.32006 (2019)
Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel Yin, Y; Le, SC; Hsu, AL; Borgnia, MJ; Yang, H; Lee, SY; Science, DOI://10.1126/science.aav9334 (2019)
Genomic analyses in African populations identify novel risk loci for cleft palate Butali, A; Mossey, PA; Adeyemo, WL et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddy402 (2019)
Laboratory mice born to wild mice have natural microbiota and model human immune responses Rosshart, SP; Herz, J; Vassallo, BG et al. Science, DOI://10.1126/science.aaw4361 (2019)
T cell stemness and dysfunction in tumors are triggered by a common mechanism Vodnala, SK; Eil, R; Kishton, RJ et al. Science, DOI://10.1126/science.aau0135 (2019)

Dynamical modeling of multi-scale variability in neuronal competition Cohen, BP; Chow, CC; Vattikuti, S; Commun Biol, DOI://10.1038/s42003-019-0555-7 (2019)
Organ-specific dose coefficients derived from Monte Carlo simulations for historical (1930s to 1960s) fluoroscopic and radiographic examinations of tuberculosis patients Borrego, D; Apostoaei, AI; Thomas, BA et al. J Radiol Prot, DOI://10.1088/1361-6498/ab2f10 (2019)
Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis Lam, KG; Brick, K; Cheng, G; Pratto, F; Camerini-Otero, RD; Nat Commun, DOI://10.1038/s41467-019-11820-7 (2019)
The bZIP mutant CEBPB (V285A) has sequence specific DNA binding propensities similar to CREB1 Ray, S; Ufot, A; Assad, N et al. Biochim Biophys Acta Gene Regul Mech, DOI://10.1016/j.bbagrm.2019.02.002 (2019)
Novel age-associated DNA methylation changes and epigenetic age acceleration in middle-aged African Americans and whites Tajuddin, SM; Hernandez, DG; Chen, BH et al. Clin Epigenetics, DOI://10.1186/s13148-019-0722-1 (2019)
Resting-state connectivity of the bed nucleus of the stria terminalis and the central nucleus of the amygdala in clinical anxiet Torrisi, S; Alvarez, GM; Gorka, AX et al. J Psychiatry Neurosci, DOI://10.1503/jpn.180150 (2019)

Insights into pediatric rhabdomyosarcoma research: Challenges and goals Yohe, ME; Heske, CM; Stewart, E et al. Pediatr Blood Cancer, DOI://10.1002/pbc.27869 (2019)
Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel Yin, Y; Wu, M; Hsu, AL et al. Nat Commun, DOI://10.1038/s41467-019-11733-5 (2019)
TET-Catalyzed 5-Carboxylcytosine Promotes CTCF Binding to Suboptimal Sequences Genome-wide Nanan, KK; Sturgill, DM; Prigge, MF et al. iScience, DOI://10.1016/j.isci.2019.07.041 (2019)
Transcriptome signature of cellular senescence Casella, G; Munk, R; Kim, KM et al. Nucleic Acids Res., DOI://10.1093/nar/gkz555 (2019)
Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual Krebs, SJ; Kwon, YD; Schramm, CA et al. Immunity, DOI://10.1016/j.immuni.2019.02.008 (2019)
Large-Scale Communication in the Human Brain Is Rhythmically Modulated through Alpha Coherence Chapeton, JI; Haque, R; Wittig, JH; Inati, SK; Zaghloul, KA; Curr. Biol., DOI://10.1016/j.cub.2019.07.014 (2019)

Transcriptional Bursting and Co-bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility Stavreva, DA; Garcia, DA; Fettweis, G et al. Mol. Cell, DOI://10.1016/j.molcel.2019.06.042 (2019)
Pathogenic variants in the AFG3L2 proteolytic domain cause SCA28 through haploinsufficiency and proteostatic stress-driven OMA1 activation Tulli, S; Del Bondio, A; Baderna, V et al. J. Med. Genet., DOI://10.1136/jmedgenet-2018-105766 (2019)
Histone methyltransferase PRDM9 is not essential for meiosis in male mice Mihola, O; Pratto, F; Brick, K et al. Genome Res., DOI://10.1101/gr.244426.118 (2019)
CRISPR/Cas9-mediated Knockout and In Situ Inversion of ORF57 Gene from All Copies of The KSHV Genome in BCBL-1 Cells BeltCappellino, A; Majerciak, V; Lobanov, A; Lack, J; Cam, M; Zheng, ZM; J. Virol., DOI://10.1128/JVI.00628-19 (2019)
Kilquist syndrome: A novel syndromic hearing loss disorder caused by homozygous deletion of SLC12A2 Macnamara, EF; Koehler, AE; D'Souza, P et al. Hum. Mutat., DOI://10.1002/humu.23722 (2019)
3' Uridylation Confers miRNAs with Non-canonical Target Repertoires Yang, A; Bofill-De Ros, X; Shao, TJ et al. Mol. Cell, DOI://10.1016/j.molcel.2019.05.014 (2019)
Pilot Trial of Adoptive Transfer of Chimeric Antigen Receptor-transduced T Cells Targeting EGFRvIII in Patients With Glioblastoma Goff, SL; Morgan, RA; Yang, JC et al. J. Immunother., DOI://10.1097/CJI.0000000000000260 (2019)
Assignment of virus and antimicrobial resistance genes to microbial hosts in a complex microbial community by combined long-read assembly and proximity ligation Bickhart, DM; Watson, M; Koren, S et al. Genome Biol., DOI://10.1186/s13059-019-1760-x (2019)
Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells Lee, PH; Yamamoto, TN; Gurusamy, D et al. J. Exp. Med., DOI://10.1084/jem.20181218 (2019)
Accurate circular consensus long-read sequencing improves variant detection and assembly of a human genome Wenger, AM; Peluso, P; Rowell, WJ et al. Nat. Biotechnol., DOI://10.1038/s41587-019-0217-9 (2019)
Transcriptome profiling of Plasmodium vivax in Saimiri monkeys identifies potential ligands for invasion Gunalan, K; Sá, JM; Moraes Barros, RR et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1818485116 (2019)
Fully automated patellofemoral MRI segmentation using holistically nested networks: Implications for evaluating patellofemoral osteoarthritis, pain, injury, pathology, and adolescent development Cheng, R; Alexandridi, NA; Smith, RM et al. Magn Reson Med, DOI://10.1002/mrm.27920 (2019)

Distinctions among real and apparent respiratory motions in human fMRI data Power, JD; Lynch, CJ; Silver, BM; Dubin, MJ; Martin, A; Jones, RM; Neuroimage, DOI://10.1016/j.neuroimage.2019.116041 (2019)
Visual temporal frequency preference shows a distinct cortical architecture using fMRI Chai, Y; Handwerker, DA; Marrett, S et al. Neuroimage, DOI://10.1016/j.neuroimage.2019.04.048 (2019)
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation Belair, C; Sim, S; Kim, KY et al. J. Cell Biol., DOI://10.1083/jcb.201811148 (2019)
Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation Nagashima, H; Mahlakõiv, T; Shih, HY et al. Immunity, DOI://10.1016/j.immuni.2019.06.009 (2019)
GATA-2-deficient mast cells limit IgE-mediated immediate hypersensitivity reactions in human subjects Desai, A; Sowerwine, K; Liu, Y et al. J. Allergy Clin. Immunol., DOI://10.1016/j.jaci.2019.05.007 (2019)
Circulating Lymphangioleiomyomatosis Tumor Cells With Loss of Heterozygosity in the TSC2 Gene Show Increased Aldehyde Dehydrogenase Activity Pacheco-Rodríguez, G; Steagall, WK; Samsel, L et al. Chest, DOI://10.1016/j.chest.2019.03.040 (2019)

A suite of automated sequence analyses reduces the number of candidate deleterious variants and reveals a difference between probands and unaffected siblings Gu, F; Wu, A; Gordon, MG et al. Genet. Med., DOI://10.1038/s41436-019-0434-0 (2019)
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer Lo, W; Parkhurst, M; Robbins, PF et al. Cancer Immunol Res, DOI://10.1158/2326-6066.CIR-18-0686 (2019)
Novel mutations in CLN6 cause late-infantile neuronal ceroid lipofuscinosis without visual impairment in two unrelated patients Chin, JJ; Behnam, B; Davids, M et al. Mol. Genet. Metab., DOI://10.1016/j.ymgme.2018.12.001 (2019)
Tumor-infiltrating human CD4+ regulatory T cells display a distinct TCR repertoire and exhibit tumor and neoantigen reactivity Ahmadzadeh, M; Pasetto, A; Jia, L et al. Sci Immunol, DOI://10.1126/sciimmunol.aao4310 (2019)
Exploring induced pluripotency in human fibroblasts via construction, validation, and application of a gene regulatory network Hamaneh, MB; Yu, YK; PLoS ONE, DOI://10.1371/journal.pone.0220742 (2019)
Multimodal imaging reveals a complex pattern of dysfunction in corticolimbic pathways in major depressive disorder Nugent, AC; Farmer, C; Evans, JW; Snider, SL; Banerjee, D; Zarate, CA; Hum Brain Mapp, DOI://10.1002/hbm.24679 (2019)
An insight into the sialome, mialome and virome of the horn fly, Haematobia irritans Ribeiro, JM; Debat, HJ; Boiani, M; Ures, X; Rocha, S; Breijo, M; BMC Genomics, DOI://10.1186/s12864-019-5984-7 (2019)
Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts Narisu, N; Rothwell, R; Vrtačnik, P et al. Aging Cell, DOI://10.1111/acel.13010 (2019)
Structures and operating principles of the replisome Gao, Y; Cui, Y; Fox, T et al. Science, DOI://10.1126/science.aav7003 (2019)
Race-ethnic differences in the associations of maternal lipid trait genetic risk scores with longitudinal fetal growth Ouidir, M; Mendola, P; Workalemahu, T et al. J Clin Lipidol, DOI://10.1016/j.jacl.2019.06.007 (2019)
The seizure onset zone drives state-dependent epileptiform activity in susceptible brain regions Diamond, JM; Chapeton, JI; Theodore, WH; Inati, SK; Zaghloul, KA; Clin Neurophysiol, DOI://10.1016/j.clinph.2019.05.032 (2019)
Immune regulation by glucocorticoids can be linked to cell type-dependent transcriptional responses Franco, LM; Gadkari, M; Howe, KN et al. J. Exp. Med., DOI://10.1084/jem.20180595 (2019)

Subtle predictive movements reveal actions regardless of social context McMahon, EG; Zheng, CY; Pereira, F; Gonzalez, R; Ungerleider, LG; Vaziri-Pashkam, M; J Vis, DOI://10.1167/19.7.16 (2019)
The Magnitude of IFN-γ Responses Is Fine-Tuned by DNA Architecture and the Non-coding Transcript of Ifng-as1 Petermann, F; Pękowska, A; Johnson, CA et al. Mol. Cell, DOI://10.1016/j.molcel.2019.06.025 (2019)
Pseudodominance of autoinflammatory disease in a single Turkish family explained by co-inheritance of haploinsufficiency of A20 and familial Mediterranean fever Horita, N; Gül, A; Aksentijevich, I; Kastner, D; Remmers, EF; Clin. Exp. Rheumatol., 0392-856X (2019)
Engineered Bcor mutations lead to acute leukemia of progenitor B-1 lymphocyte origin in a sensitized background Yin, M; Chung, YJ; Lindsley, RC et al. Blood, DOI://10.1182/blood.2018864173 (2019)
Discovering new antiretroviral compounds in Big Data chemical space of the SAVI library Savosina, PI; Stolbov, LA; Druzhilovskiy, DS; Filimonov, DA; Nicklaus, MC; Poroikov, VV; Biomed Khim, DOI://10.18097/PBMC20196502073 (2019)
Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers Parkhurst, MR; Robbins, PF; Tran, E et al. Cancer Discov, DOI://10.1158/2159-8290.CD-18-1494 (2019)

Eye in a Disk: eyeIntegration Human Pan-Eye and Body Transcriptome Database Version 1.0 Swamy, V; McGaughey, D; Invest. Ophthalmol. Vis. Sci., DOI://10.1167/iovs.19-27106 (2019)
The transcription factor TCF-1 enforces commitment to the innate lymphoid cell lineage Harly, C; Kenney, D; Ren, G et al. Nat. Immunol., DOI://10.1038/s41590-019-0445-7 (2019)
Mapping associations between polygenic risks for childhood neuropsychiatric disorders, symptoms of attention deficit hyperactivity disorder, cognition, and the brain Sudre, G; Frederick, J; Sharp, W et al. Mol. Psychiatry, DOI://10.1038/s41380-019-0350-3 (2019)
Evidence for the interaction of A3 adenosine receptor agonists at the drug-binding site (s) of Human P-glycoprotein (ABCB1) Abel, B; Tosh, DK; Durell, SR et al. Mol. Pharmacol., DOI://10.1124/mol.118.115295 (2019)
Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization Kong, R; Duan, H; Sheng, Z et al. Cell, DOI://10.1016/j.cell.2019.06.030 (2019)
Association Between Reduced Brain Glucose Metabolism and Cortical Thickness in Alcoholics: Evidence of Neurotoxicity Tomasi, DG; Wiers, CE; Shokri-Kojori, E et al. Int. J. Neuropsychopharmacol., DOI://10.1093/ijnp/pyz036 (2019)

Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition Chuang, GY; Zhou, J; Acharya, P et al. Structure, DOI://10.1016/j.str.2018.10.007 (2019)
A role for the CD38 rs3796863 polymorphism in alcohol and monetary reward: evidence from CD38 knockout mice and alcohol self-administration, [11C]-raclopride binding, and functional MRI in humans Lee, MR; Shin, JH; Deschaine, S et al. Am J Drug Alcohol Abuse, DOI://10.1080/00952990.2019.1638928 (2019)
Maternal dyslipidemia during early pregnancy and epigenetic ageing of the placenta Shrestha, D; Workalemahu, T; Tekola-Ayele, F; Epigenetics, DOI://10.1080/15592294.2019.1629234 (2019)
Spatial control of oxygen delivery to three-dimensional cultures alters cancer cell growth and gene expression Wulftange, WJ; Rose, MA; Garmendia-Cedillos, M et al. J. Cell. Physiol., DOI://10.1002/jcp.28665 (2019)
RNA-seq analysis of the salivary glands and midgut of the Argasid tick Ornithodoros rostratus Araujo, RN; Silva, NCS; Mendes-Sousa, A et al. Sci Rep, DOI://10.1038/s41598-019-42899-z (2019)
Learning deep similarity metric for 3D MR-TRUS image registration Haskins, G; Kruecker, J; Kruger, U et al. Int J Comput Assist Radiol Surg, DOI://10.1007/s11548-018-1875-7 (2019)
Blood DNA methylation and breast cancer risk: a meta-analysis of four prospective cohort studies Bodelon, C; Ambatipudi, S; Dugué, PA et al. Breast Cancer Res., DOI://10.1186/s13058-019-1145-9 (2019)
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure Sung, YJ; de Las Fuentes, L; Winkler, TW et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddz070 (2019)
Molecular recognition of nucleosomes by binding partners Kale, S; Goncearenco, A; Markov, Y; Landsman, D; Panchenko, AR; Curr. Opin. Struct. Biol., DOI://10.1016/j.sbi.2019.03.010 (2019)
Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity Canela, A; Maman, Y; Huang, SN et al. Mol. Cell, DOI://10.1016/j.molcel.2019.04.030 (2019)
RNA Sequencing in B-Cell Lymphomas Huang, DW; Dawood, M; Johnson, CA; Schmitz, R; Methods Mol. Biol., DOI://10.1007/978-1-4939-9151-8_13 (2019)
Meta-analysis of GWA studies provides new insights on the genetic architecture of skin pigmentation in recently admixed populations Lona-Durazo, F; Hernandez-Pacheco, N; Fan, S et al. BMC Genet., DOI://10.1186/s12863-019-0765-5 (2019)
Hair of the Dog: Identification of a Cis-Regulatory Module Predicted to Influence Canine Coat Composition Whitaker, DT; Ostrander, EA; Genes (Basel), DOI://10.3390/genes10050323 (2019)
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity Kilpeläinen, TO; Bentley, AR; Noordam, R et al. Nat Commun, DOI://10.1038/s41467-018-08008-w (2019)
RNA-Seq and protein mass spectrometry in microdissected kidney tubules reveal signaling processes initiating lithium-induced nephrogenic diabetes insipidus Sung, CC; Chen, L; Limbutara, K et al. Kidney Int., DOI://10.1016/j.kint.2019.02.015 (2019)
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions de Vries, PS; Brown, MR; Bentley, AR et al. Am. J. Epidemiol., DOI://10.1093/aje/kwz005 (2019)
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids Bentley, AR; Sung, YJ; Brown, MR et al. Nat. Genet., DOI://10.1038/s41588-019-0378-y (2019)
Developments in integrative modeling with dynamical interfaces Ozdemir, ES; Nussinov, R; Gursoy, A; Keskin, O; Curr. Opin. Struct. Biol., DOI://10.1016/j.sbi.2018.10.007 (2019)
Multiplicative fitness, rapid haplotype discovery, and fitness decay explain evolution of human MHC Lobkovsky, AE; Levi, L; Wolf, YI et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1714436116 (2019)
Correction: Single cell analysis of adult mouse skeletal muscle stem cells in homeostatic and regenerative conditions (doi: 10.1242/dev.174177) Dell'Orso, S; Juan, AH; Ko, KD et al. Development, DOI://10.1242/dev.181743 (2019)
Sexual dimorphisms in the transcriptomes of murine salivary glands Mukaibo, T; Gao, X; Yang, NY; Oei, MS; Nakamoto, T; Melvin, JE; FEBS Open Bio, DOI://10.1002/2211-5463.12625 (2019)
ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response Adeyemo, AA; Zaghloul, NA; Chen, G et al. Nat Commun, DOI://10.1038/s41467-019-10967-7 (2019)
Structural Insights into α-Synuclein Fibril Polymorphism: Effects of Parkinson's Disease-Related C-Terminal Truncations Ni, X; McGlinchey, RP; Jiang, J; Lee, JC; J. Mol. Biol., DOI://10.1016/j.jmb.2019.07.001 (2019)
The ribosomal prolyl-hydroxylase OGFOD1 decreases during cardiac differentiation and modulates translation and splicing Stoehr, A; Kennedy, L; Yang, Y et al. JCI Insight, DOI://10.1172/jci.insight.128496 (2019)
PTM-Logo: a program for generation of sequence logos based on position-specific background amino-acid probabilities Saethang, T; Hodge, K; Yang, CR et al. Bioinformatics, DOI://10.1093/bioinformatics/btz568 (2019)
Phosphoproteomic Identification of Vasopressin V2 Receptor-Dependent Signaling in the Renal Collecting Duct Deshpande, V; Kao, AR; Raghuram, V; Datta, A; Chou, CL; Knepper, MA; Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00281.2019 (2019)
Correction: Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression Guo, W; Machado-Vieira, R; Mathew, S et al. Transl Psychiatry, DOI://10.1038/s41398-019-0442-5 (2019)
Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis Deniset, JF; Belke, D; Lee, WY et al. Immunity, DOI://10.1016/j.immuni.2019.06.010 (2019)
Pathogenic Autoreactive T and B Cells Cross-React with Mimotopes Expressed by a Common Human Gut Commensal to Trigger Autoimmunity Ruff, WE; Dehner, C; Kim, WJ et al. Cell Host Microbe, DOI://10.1016/j.chom.2019.05.003 (2019)
Functional interplay between DEAD-box RNA helicases Ded1 and Dbp1 in preinitiation complex attachment and scanning on structured mRNAs in vivo Sen, ND; Gupta, N; K Archer, S; Preiss, T; Lorsch, JR; Hinnebusch, AG; Nucleic Acids Res., DOI://10.1093/nar/gkz595 (2019)

Parsing neurodevelopmental features of irritability and anxiety: Replication and validation of a latent variable approach Cardinale, EM; Kircanski, K; Brooks, J et al. Dev. Psychopathol., DOI://10.1017/S095457941900035X (2019)
Chemical genomics reveals histone deacetylases are required for core regulatory transcription Gryder, BE; Wu, L; Woldemichael, GM et al. Nat Commun, DOI://10.1038/s41467-019-11046-7 (2019)
Avapritinib: A Selective Inhibitor of KIT and PDGFRα that Reverses ABCB1 and ABCG2-Mediated Multidrug Resistance in Cancer Cell Lines Wu, CP; Lusvarghi, S; Wang, JC et al. Mol. Pharm., DOI://10.1021/acs.molpharmaceut.9b00274 (2019)
BORIS expression in ovarian cancer precursor cells alters the CTCF cistrome and enhances invasiveness through GALNT14 Hillman, JC; Pugacheva, EM; Barger, CJ et al. Mol. Cancer Res., DOI://10.1158/1541-7786.MCR-19-0310 (2019)
Cancer-testis antigens as biomarkers for Merkel cell carcinoma: Pitfalls and opportunities Dasgeb, B; Mehregan, D; Ring, C; Nartker, N; Brownell, I; J. Cutan. Pathol., DOI://10.1111/cup.13528 (2019)
The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons Seah, MKY; Wang, Y; Goy, PA et al. Development, DOI://10.1242/dev.170266 (2019)

Maternal Exposure to Non-nutritive Sweeteners Impacts Progeny's Metabolism and Microbiome Olivier-Van Stichelen, S; Rother, KI; Hanover, JA; Front Microbiol, DOI://10.3389/fmicb.2019.01360 (2019)
Plerixafor for the Treatment of WHIM Syndrome McDermott, DH; Pastrana, DV; Calvo, KR et al. N. Engl. J. Med., DOI://10.1056/NEJMoa1808575 (2019)
Impact of APOL1 Genetic Variants on HIV-1 Infection and Disease Progression An, P; Kirk, GD; Limou, S; Binns-Roemer, E; Kopp, JB; Winkler, CA; Front Immunol, DOI://10.3389/fimmu.2019.00053 (2019)
Amino-acid inserts of HIV-1 capsid (CA) induce CA degradation and abrogate viral infectivity: Insights for the dynamics and mechanisms of HIV-1 CA decomposition Amano, M; Bulut, H; Tamiya, S; Nakamura, T; Koh, Y; Mitsuya, H; Sci Rep, DOI://10.1038/s41598-019-46082-2 (2019)
Cholesterol-Dependent Bending Energy Is Important in Cholesterol Distribution of the Plasma Membrane Allender, DW; Sodt, AJ; Schick, M; Biophys. J., DOI://10.1016/j.bpj.2019.03.028 (2019)
Effects of Ketamine on Brain Activity During Emotional Processing: Differential Findings in Depressed Versus Healthy Control Participants Reed, JL; Nugent, AC; Furey, ML; Szczepanik, JE; Evans, JW; Zarate, CA; Biol Psychiatry Cogn Neurosci Neuroimaging, DOI://10.1016/j.bpsc.2019.01.005 (2019)

Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection Yao, C; Sun, HW; Lacey, NE et al. Nat. Immunol., DOI://10.1038/s41590-019-0403-4 (2019)
Novel Heterozygous Variants in KMT2D Associated with Holoprosencephaly Tekendo-Ngongang, C; Kruszka, P; Martinez, AF; Muenke, M; Clin. Genet., DOI://10.1111/cge.13598 (2019)
Deep neural network predicts emotional responses of the human brain from functional magnetic resonance imaging Kim, HC; Bandettini, PA; Lee, JH; Neuroimage, DOI://10.1016/j.neuroimage.2018.10.054 (2019)
A critical review of five machine learning-based algorithms for predicting protein stability changes upon mutation Fang, J Brief. Bioinformatics, DOI://10.1093/bib/bbz071 (2019)
A Genome-Wide Epstein-Barr Virus Polyadenylation Map and Its Antisense RNA to EBNA Majerciak, V; Yang, W; Zheng, J; Zhu, J; Zheng, ZM; J. Virol., DOI://10.1128/JVI.01593-18 (2019)
Interactions of Water and Alkanes: Modifying Additive Force Fields to Account for Polarization Effects Krämer, A; Pickard, FC; Huang, J et al. J Chem Theory Comput, DOI://10.1021/acs.jctc.9b00016 (2019)

CPF Recruitment to Non-canonical Transcription Termination Sites Triggers Heterochromatin Assembly and Gene Silencing Vo, TV; Dhakshnamoorthy, J; Larkin, M et al. Cell Rep, DOI://10.1016/j.celrep.2019.05.107 (2019)
Author Correction: Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis Vogt, EJ; Tokuhiro, K; Guo, M et al. Nat Commun, DOI://10.1038/s41467-019-10935-1 (2019)
The structure-activity profile of mercaptobenzamides' anti-HIV activity suggests that thermodynamics of metabolism is more important than binding affinity to the target Nikolayevskiy, H; Robello, M; Scerba, MT et al. Eur J Med Chem, DOI://10.1016/j.ejmech.2019.06.020 (2019)
Large-scale purification of functional human P-glycoprotein (ABCB1) Nandigama, K; Lusvarghi, S; Shukla, S; Ambudkar, SV; Protein Expr. Purif., DOI://10.1016/j.pep.2019.03.002 (2019)
De novo assembly of the goldfish (Carassius auratus) genome and the evolution of genes after whole-genome duplication Chen, Z; Omori, Y; Koren, S et al. Sci Adv, DOI://10.1126/sciadv.aav0547 (2019)
Molecular dissection of cone photoreceptor-enriched genes encoding transmembrane and secretory proteins Papal, S; Monti, CE; Tennison, ME; Swaroop, A; J. Neurosci. Res., DOI://10.1002/jnr.24329 (2019)

Transposable element insertions in fission yeast drive adaptation to environmental stress Esnault, C; Lee, M; Ham, C; Levin, HL; Genome Res., DOI://10.1101/gr.239699.118 (2019)
The splicing factor U2AF1 contributes to cancer progression through a noncanonical role in translation regulation Palangat, M; Anastasakis, DG; Fei, DL et al. Genes Dev., DOI://10.1101/gad.319590.118 (2019)
RASA2 and NF1; two-negative regulators of Ras with complementary functions in melanoma Arafeh, R; Di Pizio, A; Elkahloun, AG; Dym, O; Niv, MY; Samuels, Y; Oncogene, DOI://10.1038/s41388-018-0578-4 (2019)
Maternal BMI-Increasing Genetic Risk Score and Fetal Weights among Diverse US Ethnic Groups Shrestha, D; Rahman, ML; Hinkle, SN; Workalemahu, T; Tekola-Ayele, F; Obesity (Silver Spring), DOI://10.1002/oby.22499 (2019)
Author Correction: Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration Ratnapriya, R; Sosina, OA; Starostik, MR et al. Nat. Genet., DOI://10.1038/s41588-019-0430-y (2019)
Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP Li, M; Wang, Y; Banerjee, R et al. Elife, DOI://10.7554/eLife.47060 (2019)

Induced Chromosomal Aneuploidy Results in Global and Consistent Deregulation of the Transcriptome of Cancer Cells Wangsa, D; Braun, R; Stuelten, CH et al. Neoplasia, DOI://10.1016/j.neo.2019.04.009 (2019)
Sodium valproate rescues expression of TRANK1 in iPSC-derived neural cells that carry a genetic variant associated with serious mental illness Jiang, X; Detera-Wadleigh, SD; Akula, N et al. Mol. Psychiatry, DOI://10.1038/s41380-018-0207-1 (2019)
Deep learning-based muscle segmentation and quantification at abdominal CT: application to a longitudinal adult screening cohort for sarcopenia assessment Graffy, PM; Liu, J; Pickhardt, PJ; Burns, JE; Yao, J; Summers, RM; Br J Radiol, DOI://10.1259/bjr.20190327 (2019)
A parameterized digital 3D model of the Rhesus macaque face for investigating the visual processing of social cues Murphy, AP; Leopold, DA; J. Neurosci. Methods, DOI://10.1016/j.jneumeth.2019.06.001 (2019)
Association of Step Volume and Intensity With All-Cause Mortality in Older Women Lee, IM; Shiroma, EJ; Kamada, M; Bassett, DR; Matthews, CE; Buring, JE; JAMA Intern Med, DOI://10.1001/jamainternmed.2019.0899 (2019)
Small posterior fossa in Chiari I malformation affected families is significantly linked to 1q43-44 and 12q23-24.11 using whole exome sequencing Musolf, AM; Ho, WSC; Long, KA et al. Eur. J. Hum. Genet., DOI://10.1038/s41431-019-0457-7 (2019)
Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals Noordam, R; Young, WJ; Salman, R et al. J. Am. Coll. Cardiol., DOI://10.1016/j.jacc.2019.03.519 (2019)
The Impact of Anthelmintic Treatment on Human Gut Microbiota Based on Cross-Sectional and Pre- and Postdeworming Comparisons in Western Kenya Easton, AV; Quiñones, M; Vujkovic-Cvijin, I et al. MBio, DOI://10.1128/mBio.00519-19 (2019)
Novel Inter-omic Analysis Reveals Relationships Between Diverse Gut Microbiota and Host Immune Dysregulation in HLA-B27-Induced Experimental Spondyloarthritis Gill, T; Brooks, SR; Rosenbaum, JT; Asquith, M; Colbert, RA; , DOI://10.1002/art.41018 (2019)
Agouti-Related Protein 2 Is a New Player in the Teleost Stress Response System Shainer, I; Michel, M; Marquart, GD et al. Curr. Biol., DOI://10.1016/j.cub.2019.05.021 (2019)
Aberrant expression of select piRNA-pathway genes does not reactivate piRNA silencing in cancer cells Genzor, P; Cordts, SC; Bokil, NV; Haase, AD; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1904498116 (2019)
Disordered RNA chaperones can enhance nucleic acid folding via local charge screening Holmstrom, ED; Liu, Z; Nettels, D; Best, RB; Schuler, B; Nat Commun, DOI://10.1038/s41467-019-10356-0 (2019)

Long-Range RNA Structural Information via a Paramagnetically Tagged Reporter Protein Strickland, M; Catazaro, J; Rajasekaran, R et al. J. Am. Chem. Soc., DOI://10.1021/jacs.8b11384 (2019)
Lysosomal Storage and Albinism Due to Effects of a De Novo CLCN7 Variant on Lysosomal Acidification Nicoli, ER; Weston, MR; Hackbarth, M et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2019.04.008 (2019)
Aicardi-Goutières syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast cancer Deasy, SK; Uehara, R; Vodnala, SK et al. PLoS Genet., DOI://10.1371/journal.pgen.1008020 (2019)
One-carbon metabolism gene polymorphisms are associated with cognitive trajectory among African-American adults Beydoun, MA; Tajuddin, SM; Shaked, D; Beydoun, HA; Evans, MK; Zonderman, AB; Neurobiol. Aging, DOI://10.1016/j.neurobiolaging.2019.05.013 (2019)
Structural Basis of p97 Inhibition by the Site-Selective Anticancer Compound CB-5083 Tang, WK; Odzorig, T; Jin, W; Xia, D; Mol. Pharmacol., DOI://10.1124/mol.118.114256 (2019)
Fully automated prostate whole gland and central gland segmentation on MRI using holistically nested networks with short connections Cheng, R; Lay, N; Roth, HR et al. J Med Imaging (Bellingham), DOI://10.1117/1.JMI.6.2.024007 (2019)

Correlation between Disease Severity and the Intestinal Microbiome in Mycobacterium tuberculosis-Infected Rhesus Macaques Namasivayam, S; Kauffman, KD; McCulloch, JA et al. MBio, DOI://10.1128/mBio.01018-19 (2019)
Smartphone Level Test Measures Disability in Several Neurological Domains for Patients With Multiple Sclerosis Boukhvalova, AK; Fan, O; Weideman, AM et al. Front Neurol, DOI://10.3389/fneur.2019.00358 (2019)
Integrating multiple biomarkers to increase sensitivity for the detection of Onchocerca volvulus infection Bennuru, S; Oduro-Boateng, G; Osigwe, C et al. J. Infect. Dis., DOI://10.1093/infdis/jiz307 (2019)
Neutrophil Subsets, Platelets, and Vascular Disease in Psoriasis Teague, HL; Varghese, NJ; Tsoi, LC et al. JACC Basic Transl Sci, DOI://10.1016/j.jacbts.2018.10.008 (2019)
Efficacy of different dynamic functional connectivity methods to capture cognitively relevant information Xie, H; Zheng, CY; Handwerker, DA et al. Neuroimage, DOI://10.1016/j.neuroimage.2018.12.037 (2019)
TPMCalculator: one-step software to quantify mRNA abundance of genomic features Vera Alvarez, R; Pongor, LS; Mariño-Ramírez, L; Landsman, D; Bioinformatics, DOI://10.1093/bioinformatics/bty896 (2019)

The structural basis for Ras activation of PI3Kα lipid kinase Zhang, M; Jang, H; Nussinov, R; Phys Chem Chem Phys, DOI://10.1039/c9cp00101h (2019)
A chromosome-scale assembly of the major African malaria vector Anopheles funestus Ghurye, J; Koren, S; Small, ST et al. Gigascience, DOI://10.1093/gigascience/giz063 (2019)
Extensive Heterogeneity and Intrinsic Variation in Spatial Genome Organization Finn, EH; Pegoraro, G; Brandão, HB et al. Cell, DOI://10.1016/j.cell.2019.01.020 (2019)
Methylphenidate's effects on thalamic metabolism and functional connectivity in cannabis abusers and healthy controls Demiral, ŞB; Tomasi, D; Wiers, CE et al. Neuropsychopharmacology, DOI://10.1038/s41386-018-0287-2 (2019)
Neighbourhood disadvantage and depressive symptoms among adolescents followed into emerging adulthood Goldstein, RB; Lee, AK; Haynie, DL et al. J Epidemiol Community Health, DOI://10.1136/jech-2018-212004 (2019)
Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes Zubcevic, L; Hsu, AL; Borgnia, MJ; Lee, SY; Elife, DOI://10.7554/eLife.45779 (2019)

Methods for Discovering and Targeting Druggable Protein-Protein Interfaces and Their Application to Repurposing Ozdemir, ES; Halakou, F; Nussinov, R; Gursoy, A; Keskin, O; Methods Mol. Biol., DOI://10.1007/978-1-4939-8955-3_1 (2019)
The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription Malik, N; Yan, H; Moshkovich, N et al. Nat Commun, DOI://10.1038/s41467-019-10102-6 (2019)
Remarkable Rigidity of the Single α-Helical Domain of Myosin-VI As Revealed by NMR Spectroscopy Barnes, CA; Shen, Y; Ying, J et al. J. Am. Chem. Soc., DOI://10.1021/jacs.9b03116 (2019)
An integrative Bayesian approach to matrix-based analysis in neuroimaging Chen, G; Bürkner, PC; Taylor, PA et al. Hum Brain Mapp, DOI://10.1002/hbm.24686 (2019)
Crystal Structure of Bacterial Cytochrome bc1 in Complex with Azoxystrobin Reveals a Conformation Switch of the Rieske Iron-Sulfur Protein Subunit Esser, L; Zhou, F; Yu, CA; Xia, D; J. Biol. Chem., DOI://10.1074/jbc.RA119.008381 (2019)
Aberrant Clonal Hematopoiesis following Lentiviral Vector Transduction of HSPCs in a Rhesus Macaque Espinoza, DA; Fan, X; Yang, D et al. Mol. Ther., DOI://10.1016/j.ymthe.2019.04.003 (2019)

Mechanisms of Calcium Leak from Cardiac Sarcoplasmic Reticulum Revealed by Statistical Mechanics Maltsev, AV; Stern, MD; Maltsev, VA; Biophys. J., DOI://10.1016/j.bpj.2019.04.031 (2019)
REC114 Partner ANKRD31 Controls Number, Timing, and Location of Meiotic DNA Breaks Boekhout, M; Karasu, ME; Wang, J et al. Mol. Cell, DOI://10.1016/j.molcel.2019.03.023 (2019)
Mucosal vaccine efficacy against intrarectal SHIV is independent of anti-Env antibody response Sui, Y; Lewis, GK; Wang, Y et al. J. Clin. Invest., DOI://10.1172/JCI122110 (2019)
Layer-specific activation of sensory input and predictive feedback in the human primary somatosensory cortex Yu, Y; Huber, L; Yang, J et al. Sci Adv, DOI://10.1126/sciadv.aav9053 (2019)
Opportunistic Osteoporosis Screening at Routine Abdominal and Thoracic CT: Normative L1 Trabecular Attenuation Values in More than 20 000 Adults Jang, S; Graffy, PM; Ziemlewicz, TJ; Lee, SJ; Summers, RM; Pickhardt, PJ; Radiology, DOI://10.1148/radiol.2019181648 (2019)
Regulatory switch at the cytoplasmic interface controls TRPV channel gating Zubcevic, L; Borschel, WF; Hsu, AL; Borgnia, MJ; Lee, SY; Elife, DOI://10.7554/eLife.47746 (2019)

Biallelic HEPHL1 variants impair ferroxidase activity and cause an abnormal hair phenotype Sharma, P; Reichert, M; Lu, Y et al. PLoS Genet., DOI://10.1371/journal.pgen.1008143 (2019)
Heterogeneity in refractory acute myeloid leukemia Horibata, S; Gui, G; Lack, J; DeStefano, CB; Gottesman, MM; Hourigan, CS; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1902375116 (2019)
The relapsing fever spirochete Borrelia turicatae persists in the highly oxidative environment of its soft-bodied tick vector Bourret, TJ; Boyle, WK; Zalud, AK; Valenzuela, JG; Oliveira, F; Lopez, JE; Cell. Microbiol., DOI://10.1111/cmi.12987 (2019)
The skin transcriptome in hidradenitis suppurativa uncovers an antimicrobial and sweat gland gene signature which has distinct overlap with wounded skin Coates, M; Mariottoni, P; Corcoran, DL et al. PLoS ONE, DOI://10.1371/journal.pone.0216249 (2019)
Atomic resolution cryo-EM structure of a native-like CENP-A nucleosome aided by an antibody fragment Zhou, BR; Yadav, KNS; Borgnia, M et al. Nat Commun, DOI://10.1038/s41467-019-10247-4 (2019)
A Suite of Therapeutically-Inspired Nucleic Acid Logic Systems for Conditional Generation of Single-Stranded and Double-Stranded Oligonucleotides Zakrevsky, P; Bindewald, E; Humbertson, H; Viard, M; Dorjsuren, N; Shapiro, BA; Nanomaterials (Basel), DOI://10.3390/nano9040615 (2019)

XL-DNase-seq: improved footprinting of dynamic transcription factors Oh, KS; Ha, J; Baek, S; Sung, MH; Epigenetics Chromatin, DOI://10.1186/s13072-019-0277-6 (2019)
Potential Regulatory Role of Competitive Encounter Complexes in Paralogous Phosphotransferase Systems Strickland, M; Kale, S; Strub, MP et al. J. Mol. Biol., DOI://10.1016/j.jmb.2019.04.040 (2019)
Apparent diffusion coefficient changes in human brain during sleep - Does it inform on the existence of a glymphatic system Demiral, ŞB; Tomasi, D; Sarlls, J et al. Neuroimage, DOI://10.1016/j.neuroimage.2018.10.043 (2019)
Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium Kobayashi, T; Voisin, B; Kim, DY et al. Cell, DOI://10.1016/j.cell.2018.12.031 (2019)
Artificial intelligence at the intersection of pathology and radiology in prostate cancer Harmon, SA; Tuncer, S; Sanford, T; Choyke, PL; Türkbey, B; Diagn Interv Radiol, DOI://10.5152/dir.2019.19125 (2019)
Neocortical Projection Neurons Instruct Inhibitory Interneuron Circuit Development in a Lineage-Dependent Manner Wester, JC; Mahadevan, V; Rhodes, CT et al. Neuron, DOI://10.1016/j.neuron.2019.03.036 (2019)

The oral microbiome of patients undergoing treatment for severe aplastic anemia: a pilot study Ames, NJ; Barb, JJ; Ranucci, A et al. Ann. Hematol., DOI://10.1007/s00277-019-03599-w (2019)
eNetXplorer: an R package for the quantitative exploration of elastic net families for generalized linear models Candia, J; Tsang, JS; BMC Bioinformatics, DOI://10.1186/s12859-019-2778-5 (2019)
Nucleosome spacing periodically modulates nucleosome chain folding and DNA topology in circular nucleosome arrays Bass, MV; Nikitina, T; Norouzi, D; Zhurkin, VB; Grigoryev, SA; J. Biol. Chem., DOI://10.1074/jbc.RA118.006412 (2019)
The Transcriptome of the Salivary Glands of Amblyomma aureolatum Reveals the Antimicrobial Peptide Microplusin as an Important Factor for the Tick Protection Against Rickettsia rickettsii Infection Martins, LA; Malossi, CD; Galletti, MFBM et al. Front Physiol, DOI://10.3389/fphys.2019.00529 (2019)
TFE3 Xp11.2 Translocation Renal Cell Carcinoma Mouse Model Reveals Novel Therapeutic Targets and Identifies GPNMB as a Diagnostic Marker for Human Disease Baba, M; Furuya, M; Motoshima, T et al. Mol. Cancer Res., DOI://10.1158/1541-7786.MCR-18-1235 (2019)
Whole-Genome Sequences of Salmonella enterica Serovar I 4,[5],12:i:- Isolates from Swine Gonzalez, S; Harvey, RB; Scott, HM et al. Microbiol Resour Announc, DOI://10.1128/MRA.00223-19 (2019)

A Frizzled-Like Cysteine-Rich Domain in Glypican-3 Mediates Wnt Binding and Regulates Hepatocellular Carcinoma Tumor Growth in Mice Li, N; Wei, L; Liu, X et al. Hepatology, DOI://10.1002/hep.30646 (2019)
Maternal and Offspring Genetic Risk of Type 2 Diabetes and Offspring Birthweight Among African Ancestry Populations Rahman, ML; Shrestha, D; Workalemahu, T et al. J. Clin. Endocrinol. Metab., DOI://10.1210/jc.2018-02756 (2019)
Equitable Thresholding and Clustering (ETAC): A novel method for FMRI clustering in AFNI Cox, RW Brain Connect, DOI://10.1089/brain.2019.0666 (2019)
Evaluating corrections for Eddy-currents and other EPI distortions in diffusion MRI: methodology and a dataset for benchmarking Irfanoglu, MO; Sarlls, J; Nayak, A; Pierpaoli, C; Magn Reson Med, DOI://10.1002/mrm.27577 (2019)
Banana (Musa acuminata) transcriptome profiling in response to rhizobacteria: Bacillus amyloliquefaciens Bs006 and Pseudomonas fluorescens Ps006 Gamez, RM; Rodríguez, F; Vidal, NM et al. BMC Genomics, DOI://10.1186/s12864-019-5763-5 (2019)
Data-driven inference of hidden nodes in networks Hoang, DT; Jo, J; Periwal, V; Phys Rev E, DOI://10.1103/PhysRevE.99.042114 (2019)

Identifying Small Proteins by Ribosome Profiling with Stalled Initiation Complexes Weaver, J; Mohammad, F; Buskirk, AR; Storz, G; MBio, DOI://10.1128/mBio.02819-18 (2019)
Epigenetic regulation of REX1 expression and chromatin binding specificity by HMGNs Zhang, S; Deng, T; Tang, W et al. Nucleic Acids Res., DOI://10.1093/nar/gkz161 (2019)
Early-childhood social reticence predicts SCR-BOLD coupling during fear extinction recall in preadolescent youth Michalska, KJ; Feldman, JS; Ivie, EJ et al. Dev Cogn Neurosci, DOI://10.1016/j.dcn.2018.12.003 (2019)
miR-155 harnesses Phf19 to potentiate cancer immunotherapy through epigenetic reprogramming of CD8+ T cell fate Ji, Y; Fioravanti, J; Zhu, W et al. Nat Commun, DOI://10.1038/s41467-019-09882-8 (2019)
Physical Activity Patterns and Mortality: The Weekend Warrior and Activity Bouts Shiroma, EJ; Lee, IM; Schepps, MA; Kamada, M; Harris, TB; Med Sci Sports Exerc, DOI://10.1249/MSS.0000000000001762 (2019)
Defective IgA response to atypical intestinal commensals in IL-21 receptor deficiency reshapes immune cell homeostasis and mucosal immunity Cho, H; Jaime, H; de Oliveira, RP et al. Mucosal Immunol, DOI://10.1038/s41385-018-0056-x (2019)

Heritability and genetic variance of dementia with Lewy bodies Guerreiro, R; Escott-Price, V; Hernandez, DG et al. Neurobiol. Dis., DOI://10.1016/j.nbd.2019.04.004 (2019)
Differential Brain Mechanisms of Selection and Maintenance of Information during Working Memory Quentin, R; King, JR; Sallard, E et al. J. Neurosci., DOI://10.1523/JNEUROSCI.2764-18.2019 (2019)
High dimensional mediation analysis with latent variables Derkach, A; Pfeiffer, RM; Chen, TH; Sampson, JN; Biometrics, DOI://10.1111/biom.13053 (2019)
Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting Cheng, C; Xu, K; Kong, R et al. PLoS ONE, DOI://10.1371/journal.pone.0215163 (2019)
Integrated Genomic and Functional microRNA Analysis Identifies miR-30-5p as a Tumor Suppressor and Potential Therapeutic Nanomedicine in Head and Neck Cancer Saleh, AD; Cheng, H; Martin, SE et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-0716 (2019)
Frontal alpha asymmetry moderates the relations between behavioral inhibition and social-effect ERN Harrewijn, A; Buzzell, GA; Debnath, R; Leibenluft, E; Pine, DS; Fox, NA; Biol Psychol, DOI://10.1016/j.biopsycho.2018.12.014 (2019)

Characterization of the Phosphorylation Site of GRTH/DDX25 and Protein Kinase A Binding Interface Provides Structural Basis for the Design of a Non-Hormonal Male Contraceptive Raju, M; Hassan, SA; Kavarthapu, R; Anbazhagan, R; Dufau, ML; Sci Rep, DOI://10.1038/s41598-019-42857-9 (2019)
Identification of Neoantigen-Reactive Tumor-Infiltrating Lymphocytes in Primary Bladder Cancer Leko, V; McDuffie, LA; Zheng, Z et al. J. Immunol., DOI://10.4049/jimmunol.1801022 (2019)
Assessing the Role of 98 Established Loci for BMI in American Indians Muller, YL; Hanson, RL; Piaggi, P et al. Obesity (Silver Spring), DOI://10.1002/oby.22433 (2019)
A Rapid Form of Offline Consolidation in Skill Learning Bönstrup, M; Iturrate, I; Thompson, R; Cruciani, G; Censor, N; Cohen, LG; Curr. Biol., DOI://10.1016/j.cub.2019.02.049 (2019)
Whole genome sequencing of canids reveals genomic regions under selection and variants influencing morphology Plassais, J; Kim, J; Davis, BW et al. Nat Commun, DOI://10.1038/s41467-019-09373-w (2019)
Molecular constraints on CDR3 for thymic selection of MHC-restricted TCRs from a random pre-selection repertoire Lu, J; Van Laethem, F; Bhattacharya, A et al. Nat Commun, DOI://10.1038/s41467-019-08906-7 (2019)

An African-specific haplotype in MRGPRX4 is associated with menthol cigarette smoking Kozlitina, J; Risso, D; Lansu, K et al. PLoS Genet., DOI://10.1371/journal.pgen.1007916 (2019)
Evolution of All-Atom Protein Force Fields to Improve Local and Global Properties Zerze, GH; Zheng, W; Best, RB; Mittal, J; J Phys Chem Lett, DOI://10.1021/acs.jpclett.9b00850 (2019)
The mechanism of PI3Kα activation at the atomic level Zhang, M; Jang, H; Nussinov, R; Chem Sci, DOI://10.1039/c8sc04498h (2019)
Design and in Vivo Characterization of A1 Adenosine Receptor Agonists in the Native Ribose and Conformationally Constrained (N)-Methanocarba Series Tosh, DK; Rao, H; Bitant, A et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.8b01662 (2019)
Association Between Childhood Anhedonia and Alterations in Large-Scale Resting-State Networks and Task-Evoked Activation Pornpattananangkul, N; Leibenluft, E; Pine, DS; Stringaris, A; JAMA Psychiatry, DOI://10.1001/jamapsychiatry.2019.0020 (2019)
SOX2 Epidermal Overexpression Promotes Cutaneous Wound Healing via Activation of EGFR/MEK/ERK Signaling Mediated by EGFR Ligands Uchiyama, A; Nayak, S; Graf, R et al. J. Invest. Dermatol., DOI://10.1016/j.jid.2019.02.004 (2019)

APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors Roper, N; Gao, S; Maity, TK et al. Cell Rep, DOI://10.1016/j.celrep.2019.02.028 (2019)
Cases from the Undiagnosed Diseases Network: The continued value of counseling skills in a new genomic era Macnamara, EF; Schoch, K; Kelley, EG et al. J Genet Couns, DOI://10.1002/jgc4.1091 (2019)
Automated segmentation and quantification of aortic calcification at abdominal CT: application of a deep learning-based algorithm to a longitudinal screening cohort Graffy, PM; Liu, J; O'Connor, S; Summers, RM; Pickhardt, PJ; Abdom Radiol (NY), DOI://10.1007/s00261-019-02014-2 (2019)
Improvement of antibody functionality by structure-guided paratope engraftment Liu, Q; Lai, YT; Zhang, P et al. Nat Commun, DOI://10.1038/s41467-019-08658-4 (2019)
A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex Marabelli, C; Marrocco, B; Pilotto, S et al. Cell Rep, DOI://10.1016/j.celrep.2019.03.061 (2019)
Halogen bond interactions of novel HIV-1 protease inhibitors (PI)(GRL-001-15 and GRL-003-15) with the flap of protease are critical for their potent activity against wild-type and multi-PI-resistant HIV-1 variants Hattori, SI; Hayashi, H; Bulut, H et al. Antimicrob. Agents Chemother., DOI://10.1128/AAC.02635-18 (2019)

Local unfolding of the HSP27 monomer regulates chaperone activity Alderson, TR; Roche, J; Gastall, HY et al. Nat Commun, DOI://10.1038/s41467-019-08557-8 (2019)
Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7 Lo, YH; Sobhany, M; Hsu, AL et al. Nat Commun, DOI://10.1038/s41467-019-08373-0 (2019)
Absolute risks of cervical precancer among women who fulfill exiting guidelines based on HPV and cytology cotesting Landy, R; Schiffman, M; Sasieni, PD et al. Int. J. Cancer, DOI://10.1002/ijc.32268 (2019)
Decoding the 5' nucleotide bias of PIWI-interacting RNAs Stein, CB; Genzor, P; Mitra, S et al. Nat Commun, DOI://10.1038/s41467-019-08803-z (2019)
Parkinson's disease age at onset genome-wide association study: Defining heritability, genetic loci, and α-synuclein mechanisms Blauwendraat, C; Heilbron, K; Vallerga, CL et al. Mov. Disord., DOI://10.1002/mds.27659 (2019)
Inference for case-control studies with incident and prevalent cases Maziarz, M; Liu, Y; Qin, J; Pfeiffer, RM; Biometrics, DOI://10.1111/biom.13023 (2019)

Human Influenza A Virus Hemagglutinin Glycan Evolution Follows a Temporal Pattern to a Glycan Limit Altman, MO; Angel, M; Košík, I et al. MBio, DOI://10.1128/mBio.00204-19 (2019)
Network inference in stochastic systems from neurons to currencies: Improved performance at small sample size Hoang, DT; Song, J; Periwal, V; Jo, J; Phys Rev E, DOI://10.1103/PhysRevE.99.023311 (2019)
Shared genetic underpinnings of childhood obesity and adult cardiometabolic diseases Tekola-Ayele, F; Lee, A; Workalemahu, T; Sánchez-Pozos, K; Hum. Genomics, DOI://10.1186/s40246-019-0202-x (2019)
Human-Origin Influenza A (H3N2) Reassortant Viruses in Swine, Southeast Mexico Nelson, MI; Souza, CK; Trovão, NS et al. Emerging Infect. Dis., DOI://10.3201/eid2504.180779 (2019)
Posture-dependent dose coefficients of mesh-type ICRP reference computational phantoms for photon external exposures Yeom, YS; Han, H; Choi, C et al. Phys Med Biol, DOI://10.1088/1361-6560/ab0917 (2019)
Revisiting Volumes of Lipid Components in Bilayers Nagle, JF; Venable, RM; Maroclo-Kemmerling, E; Tristram-Nagle, S; Harper, PE; Pastor, RW; J Phys Chem B, DOI://10.1021/acs.jpcb.8b12010 (2019)

Synaptic potentiation and rapid antidepressant response to ketamine in treatment-resistant major depression: A replication study Nugent, AC; Wills, KE; Gilbert, JR; Zarate, CA; Psychiatry Res Neuroimaging, DOI://10.1016/j.pscychresns.2018.09.001 (2019)
Biophysical mechanisms in the mammalian respiratory oscillator re-examined with a new data-driven computational model Phillips, RS; John, TT; Koizumi, H; Molkov, YI; Smith, JC; Elife, DOI://10.7554/eLife.41555 (2019)
A Bayesian hierarchical logistic regression model of multiple informant family health histories Lin, J; Myers, MF; Koehly, LM; Marcum, CS; BMC Med Res Methodol, DOI://10.1186/s12874-019-0700-5 (2019)
Automated Computational Detection, Quantitation, and Mapping of Mitosis in Whole-Slide Images for Clinically Actionable Surgical Pathology Decision Support Puri, M; Hoover, SB; Hewitt, SM et al. J Pathol Inform, DOI://10.4103/jpi.jpi_59_18 (2019)
Control and Regulation of Substrate Selection in Cytoplasmic and Mitochondrial Catabolic Networks. A Systems Biology Analysis Cortassa, S; Aon, MA; Sollott, SJ; Front Physiol, DOI://10.3389/fphys.2019.00201 (2019)
Contrasting roles of the RSC and ISW1/CHD1 chromatin remodelers in RNA polymerase II elongation and termination Ocampo, J; Chereji, RV; Eriksson, PR; Clark, DJ; Genome Res., DOI://10.1101/gr.242032.118 (2019)

The zinc-finger protein CLAMP promotes gypsy chromatin insulator function in Drosophila Bag, I; Dale, RK; Palmer, C; Lei, EP; J. Cell. Sci., DOI://10.1242/jcs.226092 (2019)
Brain Mechanisms of Attention Orienting Following Frustration: Associations With Irritability and Age in Youths Tseng, WL; Deveney, CM; Stoddard, J et al. Am J Psychiatry, DOI://10.1176/appi.ajp.2018.18040491 (2019)
Single-cell chromatin immunocleavage sequencing (scChIC-seq) to profile histone modification Ku, WL; Nakamura, K; Gao, W et al. Nat. Methods, DOI://10.1038/s41592-019-0361-7 (2019)
Rapid and reversible suppression of ALT by DAXX in osteosarcoma cells Yost, KE; Clatterbuck Soper, SF; Walker, RL et al. Sci Rep, DOI://10.1038/s41598-019-41058-8 (2019)
Subset testing and analysis of multiple phenotypes Derkach, A; Pfeiffer, RM; Genet. Epidemiol., DOI://10.1002/gepi.22199 (2019)
CMCdG, a Novel Nucleoside Analog with Favorable Safety Features, Exerts Potent Activity against Wild-Type and Entecavir-Resistant Hepatitis B Virus Higashi-Kuwata, N; Hayashi, S; Das, D et al. Antimicrob. Agents Chemother., DOI://10.1128/AAC.02143-18 (2019)

Semi-Automated 3D Segmentation of Human Skeletal Muscle Using Focused Ion Beam-Scanning Electron Microscopic Images Caffrey, B; Maltsev, AV; Gonzalez-Freire, M; Hartnell, LM; Ferrucci, L; Subramaniam, S; J. Struct. Biol., DOI://10.1016/j.jsb.2019.03.008 (2019)
Representation and relative abundance of cell-type selective markers in whole-kidney RNA-Seq data Clark, JZ; Chen, L; Chou, CL; Jung, HJ; Lee, JW; Knepper, MA; Kidney Int., DOI://10.1016/j.kint.2018.11.028 (2019)
Activity and structural analysis of GRL-117C: a novel small molecule CCR5 inhibitor active against R5-tropic HIV-1s Nakata, H; Maeda, K; Das, D et al. Sci Rep, DOI://10.1038/s41598-019-41080-w (2019)
Cloning and characterization of a novel aspartate/glutamate racemase from the acorn worm Saccoglossus kowalevskii Uda, K; Ishizuka, N; Edashige, Y; Kikuchi, A; Radkov, AD; Moe, LA; Comp. Biochem. Physiol. B, Biochem. Mol. Biol., DOI://10.1016/j.cbpb.2019.03.006 (2019)
Inactivating Mutation in IRF8 Promotes Osteoclast Transcriptional Programs and Increases Susceptibility to Tooth Root Resorption Thumbigere-Math, V; Foster, BL; Bachu, M et al. J. Bone Miner. Res., DOI://10.1002/jbmr.3690 (2019)
S Values for neuroimaging procedures on Korean pediatric and adult head computational phantoms Villoing, D; Lee, AK; Choi, HD; Lee, C; Radiat Prot Dosimetry, DOI://10.1093/rpd/ncy287 (2019)

Population-based opportunistic osteoporosis screening: Validation of a fully automated CT tool for assessing longitudinal BMD changes Pickhardt, PJ; Lee, SJ; Liu, J et al. Br J Radiol, DOI://10.1259/bjr.20180726 (2019)
Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine Tekola-Ayele, F; Lee, A; Workalemahu, T et al. Sci Rep, DOI://10.1038/s41598-019-40834-w (2019)
Accounting for random observation time in risk prediction with longitudinal markers: An imputation approach Han, Y; Liu, D; Stat Methods Med Res, DOI://10.1177/0962280219833089 (2019)
Genomic deletions upstream of lamin B1 lead to atypical autosomal dominant leukodystrophy Nmezi, B; Giorgio, E; Raininko, R et al. Neurol Genet, DOI://10.1212/NXG.0000000000000305 (2019)
NELFE-Dependent MYC Signature Identifies a Unique Cancer Subtype in Hepatocellular Carcinoma Dang, H; Pomyen, Y; Martin, SP et al. Sci Rep, DOI://10.1038/s41598-019-39727-9 (2019)
Synthesis and evaluation of two new candidate high-affinity full agonist PET radioligands for imaging 5-HT1B receptors Lindberg, A; Lu, S; Nag, S et al. Nucl. Med. Biol., DOI://10.1016/j.nucmedbio.2019.01.005 (2019)

An insight into the sialotranscriptome and virome of Amazonian anophelines Scarpassa, VM; Debat, HJ; Alencar, RB et al. BMC Genomics, DOI://10.1186/s12864-019-5545-0 (2019)
Phosphorylation Changes in Response to Kinase Inhibitor H89 in PKA-Null Cells Limbutara, K; Kelleher, A; Yang, CR; Raghuram, V; Knepper, MA; Sci Rep, DOI://10.1038/s41598-019-39116-2 (2019)
Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase Anderson, CJ; Baird, MR; Hsu, A et al. Cell Rep, DOI://10.1016/j.celrep.2019.01.058 (2019)
DiscoverSL: an R package for multi-omic data driven prediction of synthetic lethality in cancers Das, S; Deng, X; Camphausen, K; Shankavaram, U; Bioinformatics, DOI://10.1093/bioinformatics/bty673 (2019)
Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting Chauhan, G; Adams, HHH; Satizabal, CL et al. Neurology, DOI://10.1212/WNL.0000000000006851 (2019)
Isothermal Titration Calorimetry of Be2+ with Phosphatidylserine Models Guides All-Atom Force-Field Development for LipidIon Interactions Leonard, AN; Klauda, JB; Sukharev, S; J Phys Chem B, DOI://10.1021/acs.jpcb.8b11884 (2019)

The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity Gautam, S; Fioravanti, J; Zhu, W et al. Nat. Immunol., DOI://10.1038/s41590-018-0311-z (2019)
Dosimetric Impact of a New Computational Voxel Phantom Series for the Japanese Atomic Bomb Survivors: Children and Adults Griffin, K; Paulbeck, C; Bolch, W et al. Radiat. Res., DOI://10.1667/RR15267.1 (2019)
Nanovesicles Versus Nanoparticle-Supported Lipid Bilayers: Massive Differences in Bilayer Structures and in Diffusivities of Lipid Molecules and Nanoconfined Water Jing, H; Wang, Y; Desai, PR; Ramamurthi, KS; Das, S; Langmuir, DOI://10.1021/acs.langmuir.8b03805 (2019)
ComPaSS-GWAS: A method to reduce type I error in genome-wide association studies when replication data are not available Sabourin, JA; Cropp, CD; Sung, H; Brody, LC; Bailey-Wilson, JE; Wilson, AF; Genet. Epidemiol., DOI://10.1002/gepi.22168 (2019)
Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses Kanekiyo, M; Joyce, MG; Gillespie, RA et al. Nat. Immunol., DOI://10.1038/s41590-018-0305-x (2019)
Spatial Attention Deficits Are Causally Linked to an Area in Macaque Temporal Cortex Bogadhi, AR; Bollimunta, A; Leopold, DA; Krauzlis, RJ; Curr. Biol., DOI://10.1016/j.cub.2019.01.028 (2019)
Memory T cells targeting oncogenic mutations detected in peripheral blood of epithelial cancer patients Cafri, G; Yossef, R; Pasetto, A et al. Nat Commun, DOI://10.1038/s41467-019-08304-z (2019)
Gustatory responses in macaque monkeys revealed with fMRI: Comments on taste, taste preference, and internal state Kaskan, PM; Dean, AM; Nicholas, MA; Mitz, AR; Murray, EA; Neuroimage, DOI://10.1016/j.neuroimage.2018.10.005 (2019)
Structural Differences between Pri-miRNA Paralogs Promote Alternative Drosha Cleavage and Expand Target Repertoires Bofill-De Ros, X; Kasprzak, WK; Bhandari, Y et al. Cell Rep, DOI://10.1016/j.celrep.2018.12.054 (2019)
Simultaneous targeting of linked loci in mouse embryos using base editing Lee, HK; Willi, M; Smith, HE et al. Sci Rep, DOI://10.1038/s41598-018-33533-5 (2019)
Molecular Dynamics Simulations of Membrane Permeability Venable, RM; Krämer, A; Pastor, RW; Chem. Rev., DOI://10.1021/acs.chemrev.8b00486 (2019)
Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration Ratnapriya, R; Sosina, OA; Starostik, MR et al. Nat. Genet., DOI://10.1038/s41588-019-0351-9 (2019)

Exome genotyping and linkage analysis identifies two novel linked regions and replicates two others for myopia in Ashkenazi Jewish families Simpson, CL; Musolf, AM; Li, Q et al. BMC Med. Genet., DOI://10.1186/s12881-019-0752-8 (2019)
Brain-wide cellular resolution imaging of Cre transgenic zebrafish lines for functional circuit-mapping Tabor, KM; Marquart, GD; Hurt, C et al. Elife, DOI://10.7554/eLife.42687 (2019)
Interpretation of spectroscopic data using molecular simulations for the secondary active transporter BetP Leone, V; Waclawska, I; Kossmann, K et al. J. Gen. Physiol., DOI://10.1085/jgp.201812111 (2019)
Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis Bandres-Ciga, S; Noyce, AJ; Hemani, G et al. Ann. Neurol., DOI://10.1002/ana.25431 (2019)
Whole Transcriptome Analysis of Renal Intercalated Cells Predicts Lipopolysaccharide Mediated Inhibition of Retinoid X Receptor alpha Function Saxena, V; Fitch, J; Ketz, J et al. Sci Rep, DOI://10.1038/s41598-018-36921-z (2019)
High Quality ATAC-Seq Data Recovered from Cryopreserved Breast Cell Lines and Tissue Fujiwara, S; Baek, S; Varticovski, L; Kim, S; Hager, GL; Sci Rep, DOI://10.1038/s41598-018-36927-7 (2019)

Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ewing Sarcoma: Role in Tumor Growth and Immune Evasion Heitzeneder, S; Sotillo, E; Shern, JF et al. J. Natl. Cancer Inst., DOI://10.1093/jnci/djy209 (2019)
The FLT3 inhibitor midostaurin selectively resensitizes ABCB1-overexpressing multidrug-resistant cancer cells to conventional chemotherapeutic agents Hsiao, SH; Lusvarghi, S; Huang, YH; Ambudkar, SV; Hsu, SC; Wu, CP; Cancer Lett., DOI://10.1016/j.canlet.2019.01.001 (2019)
Antimicrobial Chrysophaentin Analogs Identified from Laboratory Cultures of the Marine Microalga Chrysophaeum taylorii Davison, JR; Bewley, CA; J. Nat. Prod., DOI://10.1021/acs.jnatprod.8b00858 (2019)
Distinct Clinical and Pathological Features of Melorheostosis Associated With Somatic MAP2K1 Mutations Jha, S; Fratzl-Zelman, N; Roschger, P et al. J. Bone Miner. Res., DOI://10.1002/jbmr.3577 (2019)
The prevalence of germline DICER1 pathogenic variation in cancer populations Kim, J; Schultz, KAP; Hill, DA; Stewart, DR; Mol Genet Genomic Med, DOI://10.1002/mgg3.555 (2019)
Sequence Variation Associated with SLC12A5 Gene Expression Is Linked to Brain Structure and Function in Healthy Adults Gregory, MD; Kippenhan, JS; Callicott, JH et al. Cereb. Cortex, DOI://10.1093/cercor/bhy344 (2019)
Interleukin-12 receptor β2 from grass carp: Molecular characterization and its involvement in Aeromonas hydrophila-induced intestinal inflammation Song, XH; Tang, J; Gao, TT et al. Fish Shellfish Immunol., DOI://10.1016/j.fsi.2019.01.016 (2019)
Structure and function of an ectopic Polycomb chromatin domain De, S; Cheng, Y; Sun, MA; Gehred, ND; Kassis, JA; Sci Adv, DOI://10.1126/sciadv.aau9739 (2019)
A conserved dimer interface connects ERH and YTH family proteins to promote gene silencing Xie, G; Vo, TV; Thillainadesan, G et al. Nat Commun, DOI://10.1038/s41467-018-08273-9 (2019)
Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Epigenomic Program to Reduce Allergic Pathology Schwartz, DM; Farley, TK; Richoz, N et al. Immunity, DOI://10.1016/j.immuni.2018.12.014 (2019)
The Emergence and Functional Fitness of Memory CD4+ T Cells Require the Transcription Factor Thpok Ciucci, T; Vacchio, MS; Gao, Y et al. Immunity, DOI://10.1016/j.immuni.2018.12.019 (2019)
Next-Generation Sequencing to Diagnose Suspected Genetic Disorders Adams, DR; Eng, CM; N. Engl. J. Med., DOI://10.1056/NEJMc1814955 (2019)
Effect of amino acids on transcription and translation of key genes in E. coli K and B grown at a steady state in minimal medium Baez, A; Kumar, A; Sharma, AK; Anderson, ED; Shiloach, J; N Biotechnol, DOI://10.1016/j.nbt.2018.10.004 (2019)
The mitochondrial type IB topoisomerase drives mitochondrial translation and carcinogenesis Baechler, SA; Factor, VM; Dalla Rosa, I et al. Nat Commun, DOI://10.1038/s41467-018-07922-3 (2019)
Levels of early-childhood behavioral inhibition predict distinct neurodevelopmental pathways to pediatric anxiety Abend, R; Swetlitz, C; White, LK et al. Psychol Med, DOI://10.1017/S0033291718003999 (2019)
Secondary Metabolites from the Fungus Dictyosporium sp. and Their MALT1 Inhibitory Activities Tran, TD; Wilson, BAP; Henrich, CJ et al. J. Nat. Prod., DOI://10.1021/acs.jnatprod.8b00871 (2019)
The phenotypic landscape of a Tbc1d24 mutant mouse includes convulsive seizures resembling human early infantile epileptic encephalopathy Tona, R; Chen, W; Nakano, Y et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddy445 (2019)
Early infantile-onset epileptic encephalopathy 28 due to a homozygous microdeletion involving the WWOX gene in a region of uniparental disomy Davids, M; Markello, T; Wolfe, LA et al. Hum. Mutat., DOI://10.1002/humu.23675 (2019)

Interface-Based Structural Prediction of Novel Host-Pathogen Interactions Guven-Maiorov, E; Tsai, CJ; Ma, B; Nussinov, R; Methods Mol. Biol., DOI://10.1007/978-1-4939-8736-8_18 (2019)
Time-varying whole-brain functional network connectivity coupled to task engagement Xie H, Gonzalez-Castillo J, Handwerker D, Bandettini P Network Neuro Science, doi://10.1162/netn_a_00051 (2019)

2018 (519 papers)

Molecular Recognition between Aβ-Specific Single-Domain Antibody and Aβ Misfolded Aggregates Zhang, M; Zheng, J; Nussinov, R; Ma, B; Antibodies (Basel), DOI://10.3390/antib7030025 (2018)
Discovery of Kaposi's sarcoma herpesvirus-encoded circular RNAs and a human antiviral circular RNA Tagawa, T; Gao, S; Koparde, VN et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1816183115 (2018)
Biallelic mutations in mitochondrial tryptophanyl-tRNA synthetase cause Levodopa-responsive infantile-onset Parkinsonism Burke, EA; Frucht, SJ; Thompson, K et al. Clin. Genet., DOI://10.1111/cge.13172 (2018)
Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures Lee, JS; Adler, L; Karathia, H et al. Cell, DOI://10.1016/j.cell.2018.07.019 (2018)

Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells Bodogai, M; O'Connell, J; Kim, K et al. Sci Transl Med, DOI://10.1126/scitranslmed.aat4271 (2018)
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits Evangelou, E; Warren, HR; Mosen-Ansorena, D et al. Nat. Genet., DOI://10.1038/s41588-018-0205-x (2018)
Fully automated segmentation and quantification of visceral and subcutaneous fat at abdominal CT: application to a longitudinal adult screening cohort Lee, SJ; Liu, J; Yao, J; Kanarek, A; Summers, RM; Pickhardt, PJ; Br J Radiol, DOI://10.1259/bjr.20170968 (2018)
Analysis of type 2 diabetes and obesity genetic variants in Mexican Pima Indians: Marked allelic differentiation among Amerindians at HLA Hsueh, WC; Bennett, PH; Esparza-Romero, J et al. Ann. Hum. Genet., DOI://10.1111/ahg.12252 (2018)
A Recurrent De Novo Heterozygous COG4 Substitution Leads to Saul-Wilson Syndrome, Disrupted Vesicular Trafficking, and Altered Proteoglycan Glycosylation Ferreira, CR; Xia, ZJ; Clément, A et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2018.09.003 (2018)
Reservoir pH replica exchange Damjanovic, A; Miller, BT; Okur, A; Brooks, BR; J Chem Phys, DOI://10.1063/1.5027413 (2018)

Conformational analysis of replica exchange MD: Temperature-dependent Markov networks for FF amyloid peptides Narayan, B; Herbert, C; Yuan, Y; Rodriguez, BJ; Brooks, BR; Buchete, NV; J Chem Phys, DOI://10.1063/1.5027580 (2018)
EXP2 is a nutrient-permeable channel in the vacuolar membrane of Plasmodium and is essential for protein export via PTEX Garten, M; Nasamu, AS; Niles, JC; Zimmerberg, J; Goldberg, DE; Beck, JR; Nat Microbiol, DOI://10.1038/s41564-018-0222-7 (2018)
Non-classical monocytes as mediators of tissue destruction in arthritis Puchner, A; Saferding, V; Bonelli, M et al. Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2018-213250 (2018)
Abruptio placentae risk and genetic variations in mitochondrial biogenesis and oxidative phosphorylation: replication of a candidate gene association study Workalemahu, T; Enquobahrie, DA; Gelaye, B et al. Am. J. Obstet. Gynecol., DOI://10.1016/j.ajog.2018.08.042 (2018)
Activation of Th1 Immunity within the Tumor Microenvironment Is Associated with Clinical Response to Lenalidomide in Chronic Lymphocytic Leukemia Aue, G; Sun, C; Liu, D et al. J. Immunol., DOI://10.4049/jimmunol.1800570 (2018)
Comparison of normal tissue dose calculation methods for epidemiological studies of radiotherapy patients Mille, MM; Jung, JW; Lee, C; Kuzmin, GA; Lee, C; J Radiol Prot, DOI://10.1088/1361-6498/aabd4f (2018)

Novel variants in SPTAN1 without epilepsy: An expansion of the phenotype Gartner, V; Markello, TC; Macnamara, E et al. Am. J. Med. Genet. A, DOI://10.1002/ajmg.a.40628 (2018)
Novel truncating mutation in TENM3 in siblings with motor developmental delay, ocular coloboma, oval cornea, without microphthalmia Stephen, J; Nampoothiri, S; Kuppa, S et al. Am. J. Med. Genet. A, DOI://10.1002/ajmg.a.40658 (2018)
Exogenous ghrelin administration increases alcohol self-administration and modulates brain functional activity in heavy-drinking alcohol-dependent individuals Farokhnia, M; Grodin, EN; Lee, MR et al. Mol. Psychiatry, DOI://10.1038/mp.2017.226 (2018)
Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase Hickman, AB; Voth, AR; Ewis, H; Li, X; Craig, NL; Dyda, F; Nucleic Acids Res., DOI://10.1093/nar/gky838 (2018)
Reprogramming of regulatory network using expression uncovers sex-specific gene regulation in Drosophila Wang, Y; Cho, DY; Lee, H; Fear, J; Oliver, B; Przytycka, TM; Nat Commun, DOI://10.1038/s41467-018-06382-z (2018)
High density lipoprotein proteome is associated with cardiovascular risk factors and atherosclerosis burden as evaluated by coronary CT angiography Gordon, SM; Chung, JH; Playford, MP et al. Atherosclerosis, DOI://10.1016/j.atherosclerosis.2018.09.032 (2018)

Agreement in Histological Assessment of Mitotic Activity Between Microscopy and Digital Whole Slide Images Informs Conversion for Clinical Diagnosis Wei, BR; Halsey, CH; Hoover, SB et al. Acad Pathol, DOI://10.1177/2374289519859841 (2018)
Dynamics of Chromatin Fibers: Comparison of Monte Carlo Simulations with Force Spectroscopy Norouzi, D; Zhurkin, VB; Biophys. J., DOI://10.1016/j.bpj.2018.06.032 (2018)
GCN5L1 interacts with αTAT1 and RanBP2 to regulate hepatic α-tubulin acetylation and lysosome trafficking Wu, K; Wang, L; Chen, Y et al. J. Cell. Sci., DOI://10.1242/jcs.221036 (2018)
Sequential loss of tumor surface antigens following chimeric antigen receptor T-cell therapies in diffuse large B-cell lymphoma Shalabi, H; Kraft, IL; Wang, HW et al. Haematologica, DOI://10.3324/haematol.2017.183459 (2018)
GATA2 deficiency and human hematopoietic development modeled using induced pluripotent stem cells Jung, M; Cordes, S; Zou, J et al. Blood Adv, DOI://10.1182/bloodadvances.2018017137 (2018)
Interdomain Stabilization Impairs CD4 Binding and Improves Immunogenicity of the HIV-1 Envelope Trimer Zhang, P; Gorman, J; Geng, H et al. Cell Host Microbe, DOI://10.1016/j.chom.2018.05.002 (2018)

Genetic variations and risk of placental abruption: A genome-wide association study and meta-analysis of genome-wide association studies Workalemahu, T; Enquobahrie, DA; Gelaye, B et al. Placenta, DOI://10.1016/j.placenta.2018.04.008 (2018)
Role of humoral immunity against hepatitis B virus core antigen in the pathogenesis of acute liver failure Chen, Z; Diaz, G; Pollicino, T et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1809028115 (2018)
Bi-allelic TMEM94 Truncating Variants Are Associated with Neurodevelopmental Delay, Congenital Heart Defects, and Distinct Facial Dysmorphism Stephen, J; Maddirevula, S; Nampoothiri, S et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2018.11.001 (2018)
Using Devices to Assess Physical Activity and Sedentary Behavior in a Large Cohort Study, the Women's Health Study Lee, IM; Shiroma, EJ; Evenson, KR; Kamada, M; LaCroix, AZ; Buring, JE; J Meas Phys Behav, DOI://10.1123/jmpb.2018-0005 (2018)
Co-activation patterns in resting-state fMRI signals Liu, X; Zhang, N; Chang, C; Duyn, JH; Neuroimage, DOI://10.1016/j.neuroimage.2018.01.041 (2018)
Using mobile location data in biomedical research while preserving privacy Goldenholz, DM; Goldenholz, SR; Krishnamurthy, KB et al. J Am Med Inform Assoc, DOI://10.1093/jamia/ocy071 (2018)
Effect of Genetic Diagnosis on Patients with Previously Undiagnosed Disease Splinter, K; Adams, DR; Bacino, CA et al. N. Engl. J. Med., DOI://10.1056/NEJMoa1714458 (2018)
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes Franceschini, N; Giambartolomei, C; de Vries, PS et al. Nat Commun, DOI://10.1038/s41467-018-07340-5 (2018)
Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells Mudd, JC; Busman-Sahay, K; DiNapoli, SR et al. Nat Commun, DOI://10.1038/s41467-018-05528-3 (2018)
The transcription factors TFE3 and TFEB amplify p53 dependent transcriptional programs in response to DNA damage Brady, OA; Jeong, E; Martina, JA; Pirooznia, M; Tunc, I; Puertollano, R; Elife, DOI://10.7554/eLife.40856 (2018)
Tenectin recruits integrin to stabilize bouton architecture and regulate vesicle release at the Drosophila neuromuscular junction Wang, Q; Han, TH; Nguyen, P; Jarnik, M; Serpe, M; Elife, DOI://10.7554/eLife.35518 (2018)
CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy Fry, TJ; Shah, NN; Orentas, RJ et al. Nat. Med., DOI://10.1038/nm.4441 (2018)

Mutant IL-7Rα and mutant NRas are sufficient to induce murine T cell acute lymphoblastic leukemia Cramer, SD; Hixon, JA; Andrews, C et al. Leukemia, DOI://10.1038/s41375-017-0001-0 (2018)
Bi-allelic CCDC47 Variants Cause a Disorder Characterized by Woolly Hair, Liver Dysfunction, Dysmorphic Features, and Global Developmental Delay Morimoto, M; Waller-Evans, H; Ammous, Z et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2018.09.014 (2018)
De Novo Missense Variants in TRAF7 Cause Developmental Delay, Congenital Anomalies, and Dysmorphic Features Tokita, MJ; Chen, CA; Chitayat, D et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2018.06.005 (2018)
Evaluation of Recipients of Positive and Negative Secondary Findings Evaluations in a Hybrid CLIA-Research Sequencing Pilot Sapp, JC; Johnston, JJ; Driscoll, K et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2018.07.018 (2018)
Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression Guo, W; Machado-Vieira, R; Mathew, S et al. Transl Psychiatry, DOI://10.1038/s41398-018-0311-7 (2018)
Computation-guided analysis of paroxetine binding to hSERT reveals functionally important structural elements and dynamics Abramyan, AM; Slack, RD; Meena, S et al. Neuropharmacology, DOI://10.1016/j.neuropharm.2018.10.040 (2018)

IFIT1 Exerts Opposing Regulatory Effects on the Inflammatory and Interferon Gene Programs in LPS-Activated Human Macrophages John, SP; Sun, J; Carlson, RJ et al. Cell Rep, DOI://10.1016/j.celrep.2018.09.002 (2018)
GWAS of epigenetic aging rates in blood reveals a critical role for TERT Lu, AT; Xue, L; Salfati, EL et al. Nat Commun, DOI://10.1038/s41467-017-02697-5 (2018)
Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study Teslovich, TM; Kim, DS; Yin, X et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddy067 (2018)
Human retinoic acid-regulated CD161+ regulatory T cells support wound repair in intestinal mucosa Povoleri, GAM; Nova-Lamperti, E; Scottà, C et al. Nat. Immunol., DOI://10.1038/s41590-018-0230-z (2018)
Anthropoid primate-specific retroviral element THE1B controls expression of CRH in placenta and alters gestation length Dunn-Fletcher, CE; Muglia, LM; Pavlicev, M et al. PLoS Biol., DOI://10.1371/journal.pbio.2006337 (2018)
Interactions between genetic variation and cellular environment in skeletal muscle gene expression Taylor, DL; Knowles, DA; Scott, LJ et al. PLoS ONE, DOI://10.1371/journal.pone.0195788 (2018)
Analysis of Meiotic Double-Strand Break Initiation in Mammals Brick, K; Pratto, F; Sun, CY; Camerini-Otero, RD; Petukhova, G; Meth. Enzymol., DOI://10.1016/bs.mie.2017.11.037 (2018)
Genome-wide Identification of Structure-Forming Repeats as Principal Sites of Fork Collapse upon ATR Inhibition Shastri, N; Tsai, YC; Hile, S et al. Mol. Cell, DOI://10.1016/j.molcel.2018.08.047 (2018)
Automated Cervical Screening and Triage, Based on HPV Testing and Computer-Interpreted Cytology Yu, K; Hyun, N; Fetterman, B et al. J. Natl. Cancer Inst., DOI://10.1093/jnci/djy044 (2018)
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation Teumer, A; Chaker, L; Groeneweg, S et al. Nat Commun, DOI://10.1038/s41467-018-06356-1 (2018)
Molecular basis of Mitomycin C enhanced corneal sensory nerve repair after debridement wounding Stepp, MA; Pal-Ghosh, S; Tadvalkar, G; Li, L; Brooks, SR; Morasso, MI; Sci Rep, DOI://10.1038/s41598-018-35090-3 (2018)
MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype Plantamura, E; Dzutsev, A; Chamaillard, M et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1722372115 (2018)
Subcutaneous adipose tissue imaging of human obesity reveals two types of adipocyte membranes: Insulin-responsive and -nonresponsive McCormick, CD; Waters, HN; Bezrukov, L et al. J. Biol. Chem., DOI://10.1074/jbc.RA118.003751 (2018)
SPT6 interacts with NSD2 and facilitates interferon-induced transcription Ouda, R; Sarai, N; Nehru, V et al. FEBS Lett., DOI://10.1002/1873-3468.13069 (2018)
Isolation of Adult Spinal Cord Nuclei for Massively Parallel Single-nucleus RNA Sequencing Matson, KJE; Sathyamurthy, A; Johnson, KR; Kelly, MC; Kelley, MW; Levine, AJ; J Vis Exp, DOI://10.3791/58413 (2018)
Generation of Tumor Antigen-Specific iPSC-Derived Thymic Emigrants Using a 3D Thymic Culture System Vizcardo, R; Klemen, ND; Islam, SMR et al. Cell Rep, DOI://10.1016/j.celrep.2018.02.087 (2018)
Transcriptional profiling reveals gland-specific differential expression in the three major salivary glands of the adult mouse Gao, X; Oei, MS; Ovitt, CE; Sincan, M; Melvin, JE; Physiol. Genomics, DOI://10.1152/physiolgenomics.00124.2017 (2018)
Replacing C189 in the bZIP domain of Zta with S, T, V, or A changes DNA binding specificity to four types of double-stranded DNA Ray, S; Tillo, D; Assad, N et al. Biochem. Biophys. Res. Commun., DOI://10.1016/j.bbrc.2018.05.080 (2018)

Interferon stimulation creates chromatin marks and establishes transcriptional memory Kamada, R; Yang, W; Zhang, Y et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1720930115 (2018)
Lipid-dependence of target membrane stability during influenza viral fusion Haldar, S; Mekhedov, E; McCormick, CD; Blank, PS; Zimmerberg, J; J. Cell. Sci., DOI://10.1242/jcs.218321 (2018)
Human bone marrow assessment by single-cell RNA sequencing, mass cytometry, and flow cytometry Oetjen, KA; Lindblad, KE; Goswami, M et al. JCI Insight, DOI://10.1172/jci.insight.124928 (2018)
Structural disorder in four-repeat Tau fibrils reveals a new mechanism for barriers to cross-seeding of Tau isoforms Weismiller, HA; Murphy, R; Wei, G; Ma, B; Nussinov, R; Margittai, M; J. Biol. Chem., DOI://10.1074/jbc.RA118.005316 (2018)
Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy Yossef, R; Tran, E; Deniger, DC et al. JCI Insight, DOI://10.1172/jci.insight.122467 (2018)
Dynamic analysis of human tyrosinase intra-melanosomal domain and mutant variants to further understand oculocutaneous albinism type 1 Farney, SK; Dolinska, MB; Sergeev, YV; J Anal Pharm Res, DOI://10.15406/japlr.2018.07.00293 (2018)

Structural Constraints at the Trimer Apex Stabilize the HIV-1 Envelope in a Closed, Antibody-Protected Conformation Guzzo, C; Zhang, P; Liu, Q et al. MBio, DOI://10.1128/mBio.00955-18 (2018)
Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism Arbore, G; West, EE; Rahman, J et al. Nat Commun, DOI://10.1038/s41467-018-06706-z (2018)
Conserved mRNA-granule component Scd6 targets Dhh1 to repress translation initiation and activates Dcp2-mediated mRNA decay in vivo Zeidan, Q; He, F; Zhang, F; Zhang, H; Jacobson, A; Hinnebusch, AG; PLoS Genet., DOI://10.1371/journal.pgen.1007806 (2018)
Intraclass correlation: Improved modeling approaches and applications for neuroimaging Chen, G; Taylor, PA; Haller, SP et al. Hum Brain Mapp, DOI://10.1002/hbm.23909 (2018)
Exome sequencing of a large family identifies potential candidate genes contributing risk to bipolar disorder Zhang, T; Hou, L; Chen, DT; McMahon, FJ; Wang, JC; Rice, JP; Gene, DOI://10.1016/j.gene.2017.12.025 (2018)
Human defects in STAT3 promote oral mucosal fungal and bacterial dysbiosis Abusleme, L; Diaz, PI; Freeman, AF et al. JCI Insight, DOI://10.1172/jci.insight.122061 (2018)
Integrative analysis of the epigenetic basis of muscle-invasive urothelial carcinoma Sanford, T; Meng, MV; Railkar, R; Agarwal, PK; Porten, SP; Clin Epigenetics, DOI://10.1186/s13148-018-0451-x (2018)
Pain control through selective chemo-axotomy of centrally projecting TRPV1+ sensory neurons Sapio, MR; Neubert, JK; LaPaglia, DM et al. J. Clin. Invest., DOI://10.1172/JCI94331 (2018)
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity Turcot, V; Lu, Y; Highland, HM et al. Nat. Genet., DOI://10.1038/s41588-017-0011-x (2018)
Whole genome screen reveals a novel relationship between Wolbachia levels and Drosophila host translation Grobler, Y; Yun, CY; Kahler, DJ et al. PLoS Pathog., DOI://10.1371/journal.ppat.1007445 (2018)
Topoisomerase 3β interacts with RNAi machinery to promote heterochromatin formation and transcriptional silencing in Drosophila Lee, SK; Xue, Y; Shen, W et al. Nat Commun, DOI://10.1038/s41467-018-07101-4 (2018)
Frequency-dependent tACS modulation of BOLD signal during rhythmic visual stimulation Chai, Y; Sheng, J; Bandettini, PA; Gao, JH; Hum Brain Mapp, DOI://10.1002/hbm.23990 (2018)
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes Mahajan, A; Wessel, J; Willems, SM et al. Nat. Genet., DOI://10.1038/s41588-018-0084-1 (2018)
Neurological soft signs and cognitive performance in early childhood Alamiri, B; Nelson, C; Fitzmaurice, GM; Murphy, JM; Gilman, SE; Dev Psychol, DOI://10.1037/dev0000566 (2018)
Identifying HIPK1 as Target of miR-22-3p Enhancing Recombinant Protein Production From HEK 293 Cell by Using Microarray and HTP siRNA Screen Inwood, S; Buehler, E; Betenbaugh, M; Lal, M; Shiloach, J; Biotechnol J, DOI://10.1002/biot.201700342 (2018)
Learning recurrent dynamics in spiking networks Kim, CM; Chow, CC; Elife, DOI://10.7554/eLife.37124 (2018)
Decrypting the Heat Activation Mechanism of TRPV1 Channel by Molecular Dynamics Simulation Wen, H; Zheng, W; Biophys. J., DOI://10.1016/j.bpj.2017.10.034 (2018)
Two RNase H2 Mutants with Differential rNMP Processing Activity Reveal a Threshold of Ribonucleotide Tolerance for Embryonic Development Uehara, R; Cerritelli, SM; Hasin, N et al. Cell Rep, DOI://10.1016/j.celrep.2018.10.019 (2018)
Patterns of Physical Activity and Sedentary Behavior for Older Adults with Alzheimer's Disease, Mild Cognitive Impairment, and Cognitively Normal in Hong Kong Lu, Z; Harris, TB; Shiroma, EJ; Leung, J; Kwok, T; J. Alzheimers Dis., DOI://10.3233/JAD-180805 (2018)
Re-annotation of eight Drosophila genomes Yang, H; Jaime, M; Polihronakis, M et al. Life Sci Alliance, DOI://10.26508/lsa.201800156 (2018)
Breakthrough in GPCR Crystallography and Its Impact on Computer-Aided Drug Design Ciancetta, A; Jacobson, KA; Methods Mol. Biol., DOI://10.1007/978-1-4939-7465-8_3 (2018)
A small single-domain protein folds through the same pathway on and off the ribosome Guinn, EJ; Tian, P; Shin, M; Best, RB; Marqusee, S; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1810517115 (2018)
Development and differentiation of early innate lymphoid progenitors Harly, C; Cam, M; Kaye, J; Bhandoola, A; J. Exp. Med., DOI://10.1084/jem.20170832 (2018)
Metabolic remodelling of glucose, fatty acid and redox pathways in the heart of type 2 diabetic mice Cortassa, S; Caceres, V; Tocchetti, CG et al. J. Physiol. (Lond.), DOI://10.1113/JP276824 (2018)

The shape of the bacterial ribosome exit tunnel affects cotranslational protein folding Kudva, R; Tian, P; Pardo-Avila, F et al. Elife, DOI://10.7554/eLife.36326 (2018)
Dose coefficients of mesh-type ICRP reference computational phantoms for idealized external exposures of photons and electrons Yeom YS; Choi C; et al Nuclear Engineering and Technology, doi://10.1016/j.net.2018.12.006 (2018)
A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression Kycia, I; Wolford, BN; Huyghe, JR et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2018.02.020 (2018)
On the convergence of multi-scale free energy simulations König, G; Brooks, BR; Thiel, W; York, DM; Mol Simul, DOI://10.1080/08927022.2018.1475741 (2018)
Accelerated and Improved Differentiation of Retinal Organoids from Pluripotent Stem Cells in Rotating-Wall Vessel Bioreactors DiStefano, T; Chen, HY; Panebianco, C et al. Stem Cell Reports, DOI://10.1016/j.stemcr.2017.11.001 (2018)
Investigation of a Cluster of Sphingomonas koreensis Infections Johnson, RC; Deming, C; Conlan, S et al. N. Engl. J. Med., DOI://10.1056/NEJMoa1803238 (2018)

Hydrogen-bond dependent conformational switching: a computational challenge from experimental thermochemistry Luccarelli, J; Paton, RS; J. Org. Chem., DOI://10.1021/acs.joc.8b02436 (2018)
Intrinsic Dynamics of a Human Gene Reveal the Basis of Expression Heterogeneity Rodriguez, J; Ren, G; Day, CR; Zhao, K; Chow, CC; Larson, DR; Cell, DOI://10.1016/j.cell.2018.11.026 (2018)
Prevalence of pathogenic/likely pathogenic variants in the 24 cancer genes of the ACMG Secondary Findings v2.0 list in a large cancer cohort and ethnicity-matched controls Kim, J; Luo, W; Wang, M et al. Genome Med, DOI://10.1186/s13073-018-0607-5 (2018)
A dysbiotic microbiome triggers TH17 cells to mediate oral mucosal immunopathology in mice and humans Nicolas Dutzan, Tetsuhiro Kajikawa, Loreto Abusleme et al. Mucosal Immunity, 10.1126/scitranslmed.aat0797 (2018)
Amyloid Fibril Design: Limiting Structural Polymorphism in Alzheimer's Aβ Protofilaments Bartomiej Tywoniuk, Ye Yuan, Sarah McCartan, Beata Maria Szyd&#;owska, Florentina Tofoleanu, Bernard R. Brooks, and Nicolae-Viorel Buchete J. Phys. Chem B, 10.1021/acs.jpcb.8b07423 (2018)
Probing the hras-1Y i-motif with small molecules Sara N. Journey, Stephanie L. Alden, Will M. Hewitt, Megan L. Peach, Marc C. Nicklaus and John S. Schneekloth Jr Med. Chem. Commun.,, 10.1039/C8MD00311D (2018)

Structure activity relationship of 2-arylalkynyl-adenine derivatives as human A3 adenosine receptor antagonist Yu, J; Mannes, P; Jung, YH et al. Medchemcomm, DOI://10.1039/c8md00317c (2018)
Renal compartment-specific genetic variation analyses identify new pathways in chronic kidney disease Qiu, C; Huang, S; Park, J et al. Nat. Med., DOI://10.1038/s41591-018-0194-4 (2018)
Finding the baby in the bath water - evidence for task-specific changes in resting state functional connectivity evoked by training Steel, A; Thomas, C; Trefler, A; Chen, G; Baker, CI; Neuroimage, DOI://10.1016/j.neuroimage.2018.12.038 (2018)
Dynamic transcriptome profiling dataset of vaccinia virus obtained from long-read sequencing techniques Tombácz, D; Prazsák, I; Szucs, A; Dénes, B; Snyder, M; Boldogkoi, Z; Gigascience, DOI://10.1093/gigascience/giy139 (2018)
From Molecules to Mechanisms: Functional Proteomics and Its Application to Renal Tubule Physiology Rinschen, MM; Limbutara, K; Knepper, MA; Payne, DM; Pisitkun, T; Physiol. Rev., DOI://10.1152/physrev.00057.2017 (2018)
RNA-Protein Interactions Prevent Long RNA Duplex Formation: Implications for the Design of RNA-Based Therapeutics Bindewald, E; Dai, L; Kasprzak, WK; Kim, T; Gu, S; Shapiro, BA; Molecules, DOI://10.3390/molecules23123329 (2018)

CRISPR/Cas9-mediated gene knockin in the hydroid Hydractinia symbiolongicarpus Sanders, SM; Ma, Z; Hughes, JM et al. BMC Genomics, DOI://10.1186/s12864-018-5032-z (2018)
In Silico Mutagenesis: Decreasing the Immunogenicity of Botulinum Toxin Type A Evander Emeltan Tjoa, S; Maria Vianney, Y; Emantoko Dwi Putra, S; J. Biomol. Struct. Dyn., DOI://10.1080/07391102.2018.1559100 (2018)
BoostMe accurately predicts DNA methylation values in whole-genome bisulfite sequencing of multiple human tissues Zou, LS; Erdos, MR; Taylor, DL et al. BMC Genomics, DOI://10.1186/s12864-018-4766-y (2018)
Barcoding of Macaque Hematopoietic Stem and Progenitor Cells: A Robust Platform to Assess Vector Genotoxicity Yabe, IM; Truitt, LL; Espinoza, DA et al. Mol Ther Methods Clin Dev, DOI://10.1016/j.omtm.2018.10.009 (2018)
The Inner Ear Heat Shock Transcriptional Signature Identifies Compounds That Protect Against Aminoglycoside Ototoxicity Ryals, M; Morell, RJ; Martin, D et al. Front Cell Neurosci, DOI://10.3389/fncel.2018.00445 (2018)
A Divergent Strain of Culex pipiens-Associated Tunisia Virus in the Malaria Vector Anopheles epiroticus Debat, HJ; Ribeiro, JMC; Microbiol Resour Announc, DOI://10.1128/MRA.01026-18 (2018)

A versatile mouse model of epitope-tagged histone H3.3 to study epigenome dynamics Bachu, M; Tamura, T; Chen, C et al. J. Biol. Chem., DOI://10.1074/jbc.RA118.005550 (2018)
The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin Jang, SM; Zhang, Y; Utani, K et al. Nat Commun, DOI://10.1038/s41467-018-05177-6 (2018)
Genetic analysis of neurodegenerative diseases in a pathology cohort Blauwendraat C, Pletnikova O, Geiger, JT et al Neurobiology of Aging, 10.1016/j.neurobiolaging.2018.11.007 (2018)
Metagenomic Discovery of 83 New Human Papillomavirus Types in Patients with Immunodeficiency Pastrana, DV; Peretti, A; Welch, NL et al. mSphere, DOI://10.1128/mSphereDirect.00645-18 (2018)
Conformational stability and dynamics of the cancer-associated isoform δ133p53β are modulated by p53 peptides and p53-specific DNA Lei, J; Qi, R; Tang, Y et al. FASEB J., DOI://10.1096/fj.201801973R (2018)
Functional and association analysis of an Amerindian-derived population-specific p.(Thr280Met) variant in RBPJL, a component of the PTF1 complex Nair, AK; Sutherland, JR; Traurig, M et al. Eur. J. Hum. Genet., DOI://10.1038/s41431-017-0062-6 (2018)

hnRNP L-dependent protection of normal mRNAs from NMD subverts quality control in B cell lymphoma Kishor, A; Ge, Z; Hogg, JR; EMBO J., DOI://10.15252/embj.201899128 (2018)
Linear mixed models for association analysis of quantitative traits with next-generation sequencing data Chiu, CY; Yuan, F; Zhang, BS et al. Genet. Epidemiol., DOI://10.1002/gepi.22177 (2018)
Structural Characterization of Biomolecules through Atomistic Simulations Guided by DEER Measurements Marinelli, F; Fiorin, G; Structure, DOI://10.1016/j.str.2018.10.013 (2018)
Persistent upregulation of the β-tubulin tubb6, linked to muscle regeneration, is a source of microtubule disorganization in dystrophic muscle Randazzo, D; Khalique, U; Belanto, JJ et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddy418 (2018)
Peptidylarginine deiminases 2 and 4 modulate innate and adaptive immune responses in TLR-7-dependent lupus Liu, Y; Lightfoot, YL; Seto, N et al. JCI Insight, DOI://10.1172/jci.insight.124729 (2018)
A temporal deconvolution algorithm for multiecho functional MRI Cesar Caballero Gaudes ; Peter A. Bandettini ; Javier Gonzalez-Castillo 2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018), 10.1109/ISBI.2018.8363649 (2018)

Folding pathway of an Ig domain is conserved on and off the ribosome Tian, P; Steward, A; Kudva, R et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1810523115 (2018)
Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury Harrison, OJ; Linehan, JL; Shih, HY et al. Science, DOI://10.1126/science.aat6280 (2018)
Mosaic Y loss is moderately associated with solid tumor risk Loftfield, E; Zhou, W; Yeager, M; Chanock, SJ; Freedman, ND; Machiela, MJ; Cancer Res., DOI://10.1158/0008-5472.CAN-18-2566 (2018)
Reply to Edemir: Physiological regulation and single-cell RNA sequencing Chen, L; Lee, JW; Chou, CL et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1720333115 (2018)
AbDesigner3D: a structure-guided tool for peptide-based antibody production Saethang, T; Hodge, K; Kimkong, I; Payne, DM; Knepper, MA; Pisitkun, T; Bioinformatics, DOI://10.1093/bioinformatics/bty055 (2018)
Whole-genome sequencing of 175 Mongolians uncovers population-specific genetic architecture and gene flow throughout North and East Asia Bai, H; Guo, X; Narisu, N et al. Nat. Genet., DOI://10.1038/s41588-018-0250-5 (2018)

Helios is a key transcriptional regulator of outer hair cell maturation Chessum, L; Matern, MS; Kelly, MC et al. Nature, DOI://10.1038/s41586-018-0728-4 (2018)
Comparing the performance of selected variant callers using synthetic data and genome segmentation Bian, X; Zhu, B; Wang, M et al. BMC Bioinformatics, DOI://10.1186/s12859-018-2440-7 (2018)
Direct observation of topoisomerase IA gate dynamics Mills, M; Tse-Dinh, YC; Neuman, KC; Nat. Struct. Mol. Biol., DOI://10.1038/s41594-018-0158-x (2018)
Proximity-CLIP provides a snapshot of protein-occupied RNA elements in subcellular compartments Benhalevy, D; Anastasakis, DG; Hafner, M; Nat. Methods, DOI://10.1038/s41592-018-0220-y (2018)
An integrative systems biology approach for precision medicine in diabetic kidney disease Mulder, S; Hamidi, H; Kretzler, M; Ju, W; Diabetes Obes Metab, DOI://10.1111/dom.13416 (2018)
Identification and functional analysis of a novel G310D variant in the insulin-like growth factor 1 receptor (IGF1R) gene associated with type 2 diabetes in American Indians Muller, YL; Skelton, G; Piaggi, P et al. Diabetes Metab. Res. Rev., DOI://10.1002/dmrr.2994 (2018)
How to fold and protect mitochondrial ribosomal RNA with fewer guanines Hosseini, M; Roy, P; Sissler, M; Zirbel, CL; Westhof, E; Leontis, N; Nucleic Acids Res., DOI://10.1093/nar/gky762 (2018)
TRPV1 pore turret dictates distinct DkTx and capsaicin gating Geron, M; Kumar, R; Zhou, W; Faraldo-Gómez, JD; Vásquez, V; Priel, A; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1809662115 (2018)
Acetylation of Cytidine in mRNA Promotes Translation Efficiency Arango, D; Sturgill, D; Alhusaini, N et al. Cell, DOI://10.1016/j.cell.2018.10.030 (2018)
Mutational and Phenotypic Spectra of KCNE1 deficiency in Jervell and Lange-Nielsen Syndrome and Romano-Ward Syndrome Faridi, R; Tona, R; Brofferio, A et al. Hum. Mutat., DOI://10.1002/humu.23689 (2018)
Self-adaptive multiscaling algorithm for efficient simulations of many-protein systems in crowded conditions Hassan, SA Phys Chem Chem Phys, DOI://10.1039/c8cp05517c (2018)
Influence of Fetal and Maternal Genetic Susceptibility to Obesity on Birthweight in African Ancestry Populations Shrestha, D; Rahman, ML; Workalemahu, T; Zhu, C; Tekola-Ayele, F; Front Genet, DOI://10.3389/fgene.2018.00511 (2018)

hsegHMM: hidden Markov model-based allele-specific copy number alteration analysis accounting for hypersegmentation Choo-Wosoba, H; Albert, PS; Zhu, B; BMC Bioinformatics, DOI://10.1186/s12859-018-2412-y (2018)
Single-cell RNA sequencing of the mammalian pineal gland identifies two pinealocyte subtypes and cell type-specific daily patterns of gene expression Mays, JC; Kelly, MC; Coon, SL et al. PLoS ONE, DOI://10.1371/journal.pone.0205883 (2018)
HJURP antagonizes CENP-A mislocalization driven by the H3.3 chaperones HIRA and DAXX Nye, J; Sturgill, D; Athwal, R; Dalal, Y; PLoS ONE, DOI://10.1371/journal.pone.0205948 (2018)
Characterization of spatial and temporal development of Type I and Type II hair cells in the mouse utricle using new cell-type-specific markers McInturff, S; Burns, JC; Kelley, MW; Biol Open, DOI://10.1242/bio.038083 (2018)
Current progress and future opportunities in applications of bioinformatics for biodefense and pathogen detection: report from the Winter Mid-Atlantic Microbiome Meet-up, College Park, MD, January 10, 2018 Meisel, JS; Nasko, DJ; Brubach, B et al. Microbiome, DOI://10.1186/s40168-018-0582-5 (2018)
Targeted deletion of an NRL- and CRX-regulated alternative promoter specifically silences FERM and PDZ domain containing 1 (Frmpd1) in rod photoreceptors Campla, CK; Mast, H; Dong, L et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddy388 (2018)
Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination Steklov, M; Pandolfi, S; Baietti, MF et al. Science, DOI://10.1126/science.aap7607 (2018)
The effect of repeated stimulated granulocyte donations on hematopoietic indexes in donors: a 24-year donor center experience Szymanski, J; Troendle, J; Leitman, S; Hong, H; Yau, YY; Cantilena, C; Transfusion, DOI://10.1111/trf.15000 (2018)
Mechanism of FACT removal from transcribed genes by anticancer drugs curaxins Chang, HW; Valieva, ME; Safina, A et al. Sci Adv, DOI://10.1126/sciadv.aav2131 (2018)
Quantifying differences between passive and task-evoked intrinsic functional connectivity in a large-scale brain simulation Ulloa, A; Horwitz, B; Brain Connect, DOI://10.1089/brain.2018.0620 (2018)
Genome Sequences of 15 Klebsiella sp. Isolates from Sugarcane Fields in Colombia's Cauca Valley Medina-Cordoba, LK; Chande, AT; Rishishwar, L et al. Genome Announc, DOI://10.1128/genomeA.00104-18 (2018)
Amycomicin is a potent and specific antibiotic discovered with a targeted interaction screen Pishchany, G; Mevers, E; Ndousse-Fetter, S et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1807613115 (2018)
ONC201 kills breast cancer cells in vitro by targeting mitochondria Greer, YE; Porat-Shliom, N; Nagashima, K et al. Oncotarget, DOI://10.18632/oncotarget.24862 (2018)
RNA sequencing of kidney distal tubule cells reveals multiple mediators of chronic aldosterone action Poulsen, SB; Limbutara, K; Fenton, RA; Pisitkun, T; Christensen, BM; Physiol. Genomics, DOI://10.1152/physiolgenomics.00084.2017 (2018)
Transcriptome signature for dietary fructose-specific changes in rat renal cortex: A quantitative approach to physiological relevance Gonzalez-Vicente, A; Garvin, JL; Hopfer, U; PLoS ONE, DOI://10.1371/journal.pone.0201293 (2018)
Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists Tosh, DK; Ciancetta, A; Mannes, P et al. ACS Omega, DOI://10.1021/acsomega.8b01237 (2018)
High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping Czerniecki, SM; Cruz, NM; Harder, JL et al. Cell Stem Cell, DOI://10.1016/j.stem.2018.04.022 (2018)
Effect of over expressing protective antigen on global gene transcription in Bacillus anthracis BH500 Sharma, AK; Leppla, SH; Pomerantsev, AP; Shiloach, J; Sci Rep, DOI://10.1038/s41598-018-34196-y (2018)

Genetic Ancestry of Hadza and Sandawe Peoples Reveals Ancient Population Structure in Africa Shriner, D; Tekola-Ayele, F; Adeyemo, A; Rotimi, CN; Genome Biol Evol, DOI://10.1093/gbe/evy051 (2018)
Correction: A Novel, Noncanonical BMP Pathway Modulates Synapse Maturation at the Drosophila Neuromuscular Junction Sulkowski, MJ; Han, TH; Ott, C et al. PLoS Genet., DOI://10.1371/journal.pgen.1007343 (2018)
--Mitochondrial ATP synthase dimers spontaneously associate due to a long-range membrane-induced force Anselmi, C; Davies, KM; Faraldo-Gómez, JD; J. Gen. Physiol., DOI://10.1085/jgp.201812033 (2018)
Phenotypic expansion in DDX3X - a common cause of intellectual disability in females Wang, X; Posey, JE; Rosenfeld, JA et al. Ann Clin Transl Neurol, DOI://10.1002/acn3.622 (2018)
A Comparison of QM/MM Simulations with and without the Drude Oscillator Model Based on Hydration Free Energies of Simple Solutes König, G; Pickard, FC; Huang, J et al. Molecules, DOI://10.3390/molecules23102695 (2018)
BRG1 governs glucocorticoid receptor interactions with chromatin and pioneer factors across the genome Hoffman, JA; Trotter, KW; Ward, JM; Archer, TK; Elife, DOI://10.7554/eLife.35073 (2018)

Mitochondrial chaotic dynamics: Redox-energetic behavior at the edge of stability Kembro, JM; Cortassa, S; Lloyd, D; Sollott, SJ; Aon, MA; Sci Rep, DOI://10.1038/s41598-018-33582-w (2018)
Towards Personalized Medicine: An Improved De Novo Assembly Procedure for Early Detection of Drug Resistant HIV Minor Quasispecies in Patient Samples Huang, C; Sam, V; Du, S et al. Bioinformation, DOI://10.6026/97320630014449 (2018)
JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies Sanchez, GAM; Reinhardt, A; Ramsey, S et al. J. Clin. Invest., DOI://10.1172/JCI98814 (2018)
Collecting duct principal, but not intercalated, cell prorenin receptor regulates renal sodium and water excretion Ramkumar, N; Stuart, D; Mironova, E et al. Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00122.2018 (2018)
Detection and Distinction of Mild Brain Injury Effects in a Ferret Model Using Diffusion Tensor MRI (DTI) and DTI-Driven Tensor-Based Morphometry (D-TBM) Hutchinson, EB; Schwerin, SC; Radomski, KL et al. Front Neurosci, DOI://10.3389/fnins.2018.00573 (2018)
Approaches to the discovery of non-invasive urinary biomarkers of prostate cancer Jedinak, A; Loughlin, KR; Moses, MA; Oncotarget, DOI://10.18632/oncotarget.25946 (2018)
Sequence-based searching of custom proteome and transcriptome databases Medvar, B; Sarkar, A; Knepper, M; Pisitkun, T; Physiol Rep, DOI://10.14814/phy2.13846 (2018)
STAT5B: A Differential Regulator of the Life and Death of CD4+ Effector Memory T Cells Majri, SS; Fritz, JM; Villarino, AV et al. J. Immunol., DOI://10.4049/jimmunol.1701133 (2018)
Tilted, Uninterrupted, Monomeric HIV-1 gp41 Transmembrane Helix from Residual Dipolar Couplings Chiliveri, SC; Louis, JM; Ghirlando, R; Baber, JL; Bax, A; J. Am. Chem. Soc., DOI://10.1021/jacs.7b10245 (2018)
A function-blocking CD47 antibody modulates extracellular vesicle-mediated intercellular signaling between breast carcinoma cells and endothelial cells Kaur, S; Elkahloun, AG; Singh, SP; Arakelyan, A; Roberts, DD; J Cell Commun Signal, DOI://10.1007/s12079-017-0428-0 (2018)
Identification and functional analysis of SOX10 phosphorylation sites in melanoma Cronin, JC; Loftus, SK; Baxter, LL; Swatkoski, S; Gucek, M; Pavan, WJ; PLoS ONE, DOI://10.1371/journal.pone.0190834 (2018)
Practical issues in using generalized estimating equations for inference on transitions in longitudinal data: What is being estimated Bible, J; Albert, PS; Simons-Morton, BG; Liu, D; Stat Med, DOI://10.1002/sim.8014 (2018)

Whole-exome sequencing of nevoid basal cell carcinoma syndrome families and review of Human Gene Mutation Database PTCH1 mutation data Gianferante, DM; Rotunno, M; Dean, M et al. Mol Genet Genomic Med, DOI://10.1002/mgg3.498 (2018)
Renal release of Ac-SDKP is part of an antifibrotic peptidergic system in the kidney Romero, CA; Kumar, N; Nakagawa, P et al. Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00270.2018 (2018)
Expanded skin virome in DOCK8-deficient patients Tirosh, O; Conlan, S; Deming, C et al. Nat. Med., DOI://10.1038/s41591-018-0211-7 (2018)
Nuclear Transcriptomes of the Seven Neuronal Cell Types That Constitute the Drosophila Mushroom Bodies Shih, MM; Davis, FP; Henry, GL; Dubnau, J; G3 (Bethesda), DOI://10.1534/g3.118.200726 (2018)
Integrated Epigenetic Mapping of Human and Mouse Salivary Gene Regulation Michael, DG; Pranzatelli, TJF; Warner, BM; Yin, H; Chiorini, JA; J. Dent. Res., DOI://10.1177/0022034518806518 (2018)
A fast adaptive algorithm for computing whole-genome homology maps Chirag Jain, Sergey Koren, Alexander Dilthey, Adam M Phillippy, and Srinivas Aluru Bioinformatics, doi://10.1093/bioinformatics/bty597 (2018)

Clonal expansion and compartmentalized maintenance of rhesus macaque NK cell subsets Wu, C; Espinoza, DA; Koelle, SJ et al. Sci Immunol, DOI://10.1126/sciimmunol.aat9781 (2018)
Expanding the phenotype of COPA syndrome: a kindred with typical and atypical features Taveira-DaSilva, AM; Markello, TC; Kleiner, DE et al. J. Med. Genet., DOI://10.1136/jmedgenet-2018-105560 (2018)
RefSeq database growth influences the accuracy of k-mer-based lowest common ancestor species identification Nasko, DJ; Koren, S; Phillippy, AM; Treangen, TJ; Genome Biol., DOI://10.1186/s13059-018-1554-6 (2018)
Non-canonical Drosophila X chromosome dosage compensation and repressive topologically associated domains Lee, H; Oliver, B; Epigenetics Chromatin, DOI://10.1186/s13072-018-0232-y (2018)
Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke Cole, JW; Xu, H; Ryan, K et al. PLoS ONE, DOI://10.1371/journal.pone.0206554 (2018)
Genomic and Transcriptomic Characterization Links Cell Lines with Aggressive Head and Neck Cancers Cheng, H; Yang, X; Si, H et al. Cell Rep, DOI://10.1016/j.celrep.2018.10.007 (2018)
Modulation of Cl- signaling and ion transport by recruitment of kinases and phosphatases mediated by the regulatory protein IRBIT Vachel, L; Shcheynikov, N; Yamazaki, O et al. Sci Signal, DOI://10.1126/scisignal.aat5018 (2018)
Body-weight dependent dose coefficients for adults exposed to idealised external photon fields Lienard A Chang David Borrego and Choonsik Lee J. Radiological Protection, vol 38, no 4 (2018)
Molecular Determinants of Aβ42 Adsorption to Amyloid Fibril Surfaces Bellaiche, MMJ; Best, RB; J Phys Chem Lett, DOI://10.1021/acs.jpclett.8b02375 (2018)
Organ Dose Estimation accounting for uncertainty for pediatric and young adult CT scans in the United Kingdom Lee, C; Journy, N; Moroz, BE et al. Radiat Prot Dosimetry, DOI://10.1093/rpd/ncy184 (2018)
Argonaute2 attenuates active transcription by limiting RNA Polymerase II elongation in Drosophila melanogaster Nazer, E; Dale, RK; Palmer, C; Lei, EP; Sci Rep, DOI://10.1038/s41598-018-34115-1 (2018)
Enhanced expression and distinctive characterization of a long-acting FGF21 and its potential to alleviate nonalcoholic steatohepatitis Yin, J; Bao, L; Chen, R; Gao, W; Gao, X; Yao, W; Biochimie, DOI://10.1016/j.biochi.2018.05.020 (2018)

Brain regions modulated during covert visual attention in the macaque Bogadhi, AR; Bollimunta, A; Leopold, DA; Krauzlis, RJ; Sci Rep, DOI://10.1038/s41598-018-33567-9 (2018)
Variable population prevalence estimates of germline TP53 variants: A gnomAD-based analysis de Andrade, KC; Frone, MN; Wegman-Ostrosky, T et al. Hum. Mutat., DOI://10.1002/humu.23673 (2018)
De novo assembly of haplotype-resolved genomes with trio binning Koren, S; Rhie, A; Walenz, BP et al. Nat. Biotechnol., DOI://10.1038/nbt.4277 (2018)
Structural interpretation of DNA-protein hydroxyl-radical footprinting experiments with high resolution using HYDROID Shaytan, AK; Xiao, H; Armeev, GA et al. Nat Protoc, DOI://10.1038/s41596-018-0048-z (2018)
Cell-type-specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes Zhang, T; Choi, J; Kovacs, MA et al. Genome Res., DOI://10.1101/gr.233304.117 (2018)
Peptide-MHC (pMHC) binding to a human antiviral T cell receptor induces long-range allosteric communication between pMHC- and CD3-binding sites Rangarajan, S; He, Y; Chen, Y et al. J. Biol. Chem., DOI://10.1074/jbc.RA118.003832 (2018)

Comparison of the umbrella sampling and the double decoupling method in binding free energy predictions for SAMPL6 octa-acid host-guest challenges Nishikawa, N; Han, K; Wu, X; Tofoleanu, F; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-018-0166-2 (2018)
Molecular Recognition between Aβ-Specific Single-Domain Antibody and Aβ Misfolded Aggregates Mingzhen Zhang, Jie Zheng, Ruth Nussinov and Buyong Ma Antibodies, doi:10.3390/antib7030025 (2018)
Single-Molecule Analysis Reveals Linked Cycles of RSC Chromatin Remodeling and Ace1p Transcription Factor Binding in Yeast Mehta, GD; Ball, DA; Eriksson, PR et al. Mol. Cell, DOI://10.1016/j.molcel.2018.09.009 (2018)
Optimizing and evaluating biomarker combinations as trial-level general surrogates Gabriel, EE; Sachs, MC; Daniels, MJ; Halloran, ME; Stat Med, DOI://10.1002/sim.7996 (2018)
Global genetic insight contributed by consanguineous Pakistani families segregating hearing loss Richard, EM; Santos-Cortez, RL; Faridi, R et al. Hum. Mutat., DOI://10.1002/humu.23666 (2018)
Accelerating QM/MM Free Energy Computations via Intramolecular Force Matching Hudson, PS; Boresch, S; Rogers, DM; Woodcock, HL; J Chem Theory Comput, DOI://10.1021/acs.jctc.8b00517 (2018)

Loss of functional connectivity is an early imaging marker in primary lateral sclerosis Clark, MG; Smallwood Shoukry, R; Huang, CJ; Danielian, LE; Bageac, D; Floeter, MK; Amyotroph Lateral Scler Frontotemporal Degener, DOI://10.1080/21678421.2018.1517180 (2018)
QuagmiR: A Cloud-based Application for IsomiR Big Data Analytics Bofill-De Ros, X; Chen, K; Chen, S et al. Bioinformatics, DOI://10.1093/bioinformatics/bty843 (2018)
Estimating onset time from longitudinal data in the presence of measurement error with application to estimating gestational age from maternal anthropometry during pregnancy Ortega-Villa, AM; Albert, PS; Stat Med, DOI://10.1002/sim.7955 (2018)
CRISPro: An Automated Pipeline for Protein Conformation Stabilization by Proline Rawi, R; Shen, CH; Kwong, PD; Chuang, GY; J Chem Inf Model, DOI://10.1021/acs.jcim.8b00592 (2018)
Impact of induced anxiety on neural responses to monetary incentives Gorka, AX; Fuchs, B; Grillon, C; Ernst, M; Soc Cogn Affect Neurosci, DOI://10.1093/scan/nsy082 (2018)
Antigen binding allosterically promotes Fc receptor recognition Zhao, J; Nussinov, R; Ma, B; MAbs, DOI://10.1080/19420862.2018.1522178 (2018)

Progressing super-enhancer landscape during mammary differentiation controls tissue-specific gene regulation Lee, HK; Willi, M; Shin, HY; Liu, C; Hennighausen, L; Nucleic Acids Res., DOI://10.1093/nar/gky891 (2018)
Early life disadvantage and adult adiposity: tests of sensitive periods during childhood and behavioural mediation in adulthood Gilman, SE; Huang, YT; Jimenez, MP et al. Int J Epidemiol, DOI://10.1093/ije/dyy199 (2018)
Origin of Internal Friction in Disordered Proteins Depends on Solvent Quality Zheng, W; Hofmann, H; Schuler, B; Best, RB; J Phys Chem B, DOI://10.1021/acs.jpcb.8b07425 (2018)
Mutation frequency is not increased in CRISPR-Cas9-edited mice Willi, M; Smith, HE; Wang, C; Liu, C; Hennighausen, L; Nat. Methods, DOI://10.1038/s41592-018-0148-2 (2018)
Force matching as a stepping stone to QM/MM CB[8] host/guest binding free energies: a SAMPL6 cautionary tale Hudson, PS; Han, K; Woodcock, HL; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-018-0165-3 (2018)
An explicit-solvent hybrid QM and MM approach for predicting pKa of small molecules in SAMPL6 challenge Prasad, S; Huang, J; Zeng, Q; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-018-0167-1 (2018)
A Bayesian multi-dimensional couple-based latent risk model with an application to infertility Hwang, BS; Chen, Z; Louis, GMB; Albert, PS; Biometrics, DOI://10.1111/biom.12972 (2018)
Nutrient-Driven O-GlcNAcylation at Promoters Impacts Genome-Wide RNA Pol II Distribution Krause, MW; Love, DC; Ghosh, SK et al. Front Endocrinol (Lausanne), DOI://10.3389/fendo.2018.00521 (2018)
Evidence for the critical role of transmembrane helices 1 and 7 in substrate transport by human P-glycoprotein (ABCB1) Sajid, A; Lusvarghi, S; Chufan, EE; Ambudkar, SV; PLoS ONE, DOI://10.1371/journal.pone.0204693 (2018)
Principles of nucleosome organization revealed by single-cell micrococcal nuclease sequencing Lai, B; Gao, W; Cui, K et al. Nature, DOI://10.1038/s41586-018-0567-3 (2018)
Genetic history of Chad Shriner, D; Rotimi, CN; Am. J. Phys. Anthropol., DOI://10.1002/ajpa.23711 (2018)
Visualization and Interpretation of Convolutional Neural Network Predictions in Detecting Pneumonia in Pediatric Chest Radiographs S. Rajaraman, S. Candemir, I. Kim, G. Thoma, S. Antani Appl. Sci. , doi://10.3390/app8101715 (2018)

Identifying core biological processes distinguishing human eye tissues with precise systems-level gene expression analyses and weighted correlation networks Bryan, JM; Fufa, TD; Bharti, K; Brooks, BP; Hufnagel, RB; McGaughey, DM; Hum. Mol. Genet., DOI://10.1093/hmg/ddy239 (2018)
Structural elements required for coupling ion and substrate transport in the neurotransmitter transporter homolog LeuT Zhang, YW; Tavoulari, S; Sinning, S; Aleksandrova, AA; Forrest, LR; Rudnick, G; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1716870115 (2018)
Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia Kim, MY; Yu, KR; Kenderian, SS et al. Cell, DOI://10.1016/j.cell.2018.05.013 (2018)
Extensive sex differences at the initiation of genetic recombination Brick, K; Thibault-Sennett, S; Smagulova, F et al. Nature, DOI://10.1038/s41586-018-0492-5 (2018)
Transcriptional outcomes and kinetic patterning of gene expression in response to NF-κB activation Zhao, M; Joy, J; Zhou, W et al. PLoS Biol., DOI://10.1371/journal.pbio.2006347 (2018)
Proteomic approaches in kidney disease biomarker discovery Wu, Q; Fenton, RA; Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00421.2018 (2018)

Whole genome sequencing data for two individuals of Pakistani descent Khan, SY; Kabir, F; M'Hamdi, O et al. Sci Data, DOI://10.1038/sdata.2018.174 (2018)
Peptide and Protein Structure Prediction with a Simplified Continuum Solvent Model Steinbach, PJ J Phys Chem B, DOI://10.1021/acs.jpcb.8b07264 (2018)
Relation between single-molecule properties and phase behavior of intrinsically disordered proteins Dignon, GL; Zheng, W; Best, RB; Kim, YC; Mittal, J; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1804177115 (2018)
Robust Hund rule without Coulomb repulsion and exclusion principle in quantum antiferromagnetic chains of composite half spins Duki, SF; Yu, YK; J Phys Condens Matter, DOI://10.1088/1361-648X/aae169 (2018)
Half blind superiority tests for clinical trials of anti-infective drugs Follmann, D; Brittain, E; Lumbard, K; Stat Med, DOI://10.1002/sim.7954 (2018)
Random forest based classification of alcohol dependence patients and healthy controls using resting state MRI Zhu, X; Du, X; Kerich, M; Lohoff, FW; Momenan, R; Neurosci. Lett., DOI://10.1016/j.neulet.2018.04.007 (2018)
A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A Ciftci-Yilmaz, S; Au, WC; Mishra, PK et al. Genetics, DOI://10.1534/genetics.118.301305 (2018)
DNA methylation age is accelerated in alcohol dependence Rosen, AD; Robertson, KD; Hlady, RA et al. Transl Psychiatry, DOI://10.1038/s41398-018-0233-4 (2018)
Dynamics of Genome Alterations in Crohn's Disease-Associated Colorectal Carcinogenesis Hirsch, D; Wangsa, D; Zhu, YJ et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-0630 (2018)
EWS-FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine-glycine biosynthesis Sen, N; Cross, AM; Lorenzi, PL et al. Mol. Carcinog., DOI://10.1002/mc.22849 (2018)
Aneuploidy, TP53 mutation, and amplification of MYC correlate with increased intratumor heterogeneity and poor prognosis of breast cancer patients Oltmann, J; Heselmeyer-Haddad, K; Hernandez, LS et al. Genes Chromosomes Cancer, DOI://10.1002/gcc.22515 (2018)
Multiple claudin-claudin cis interfaces are required for tight junction strand formation and inherent flexibility Zhao, J; Krystofiak, ES; Ballesteros A et al. Comm. Biol. , doi://10.1038/s42003-018-0051-5 (2018)

Calmodulin (CaM) Activates PI3Kα by Targeting the "Soft" CaM-Binding Motifs in Both the nSH2 and cSH2 Domains of p85α Zhang M, Li Z, Wang G et al. J. Phys. Chem B, doi://10.1021/acs.jpcb.8b05982 (2018)
Functional and physical interaction between yeast Hsp90 and Hsp70 Kravats, AN; Hoskins, JR; Reidy, M et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1719969115 (2018)
Neurophysiological Changes Associated with Antidepressant Response to Ketamine Not Observed in a Negative Trial of Scopolamine in Major Depressive Disorder Park, L; Furey, M; Nugent, AC et al. Int. J. Neuropsychopharmacol., DOI://10.1093/ijnp/pyy051 (2018)
The High Genetic Barrier of EFdA/MK-8591 Stems from Strong Interactions with the Active Site of Drug-Resistant HIV-1 Reverse Transcriptase Takamatsu, Y; Das, D; Kohgo, S et al. Cell Chem Biol, DOI://10.1016/j.chembiol.2018.07.014 (2018)
Mapping discontinuous epitopes for MRK-16, UIC2 and 4E3 antibodies to extracellular loops 1 and 4 of human P-glycoprotein Vahedi, S; Lusvarghi, S; Pluchino, K et al. Sci Rep, DOI://10.1038/s41598-018-30984-8 (2018)
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure Sung, YJ; Winkler, TW; de Las Fuentes, L et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2018.01.015 (2018)

Heterogeneity of calcium clock functions in dormant, dysrhythmically and rhythmically firing single pacemaker cells isolated from SA node Kim, MS; Maltsev, AV; Monfredi, O et al. Cell Calcium, DOI://10.1016/j.ceca.2018.07.002 (2018)
Targeted RNA-sequencing for the quantification of measurable residual disease in acute myeloid leukemia Dillon, LW; Hayati, S; Roloff, GW et al. Haematologica, DOI://10.3324/haematol.2018.203133 (2018)
Trac-looping measures genome structure and chromatin accessibility Lai, B; Tang, Q; Jin, W et al. Nat. Methods, DOI://10.1038/s41592-018-0107-y (2018)
Experience-dependent structural plasticity targets dynamic filopodia in regulating dendrite maturation and synaptogenesis Sheng, C; Javed, U; Gibbs, M et al. Nat Commun, DOI://10.1038/s41467-018-05871-5 (2018)
Proteomic determination of the lysine acetylome and phosphoproteome in the rat native inner medullary collecting duct Hyndman, KA; Yang, CR; Jung, HJ; Umejiego, EN; Chou, CL; Knepper, MA; Physiol. Genomics, DOI://10.1152/physiolgenomics.00029.2018 (2018)
Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours Ma, X; Liu, Y; Liu, Y et al. Nature, DOI://10.1038/nature25795 (2018)

Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa Li, L; Jiao, X; D'Atri, I et al. PLoS Genet., DOI://10.1371/journal.pgen.1007504 (2018)
Argonaute-miRNA Complexes Silence Target mRNAs in the Nucleus of Mammalian Stem Cells Sarshad, AA; Juan, AH; Muler, AIC et al. Mol. Cell, DOI://10.1016/j.molcel.2018.07.020 (2018)
Identification of Retinal Ganglion Cell Firing Patterns Using Clustering Analysis Supplied with Failure Diagnosis Ghahari, A; Kumar, SR; Badea, TC; Int J Neural Syst, DOI://10.1142/S0129065718500089 (2018)
A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity Béziat, V; Li, J; Lin, JX et al. Sci Immunol, DOI://10.1126/sciimmunol.aat4956 (2018)
TM6SF2 Promotes Lipidation and Secretion of Hepatitis C Virus in Infected Hepatocytes Boyer, A; Park, SB; de Boer, Y; Li, Q; Liang, TJ; Gastroenterology, DOI://10.1053/j.gastro.2018.08.027 (2018)
Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease Yao, C; Chen, G; Song, C et al. Nat Commun, DOI://10.1038/s41467-018-05512-x (2018)
Distributed cortical structural properties contribute to motor cortical excitability and inhibition Dayan, E; López-Alonso, V; Liew, SL; Cohen, LG; Brain Struct Funct, DOI://10.1007/s00429-018-1722-1 (2018)
Dysregulated neutrophil responses and neutrophil extracellular trap formation and degradation in PAPA syndrome Mistry, P; Carmona-Rivera, C; Ombrello, AK et al. Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2018-213746 (2018)
Absolute and relative pKa predictions via a DFT approach applied to the SAMPL6 blind challenge Zeng, Q; Jones, MR; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-018-0150-x (2018)
Conformational ensemble of disordered proteins probed by solvent Paramagnetic Relaxation Enhancement (sPRE) Kooshapur, H; Schwieters, C; Tjandra, N; Angew. Chem. Int. Ed. Engl., DOI://10.1002/anie.201807365 (2018)
On testing for spatial correspondence between maps of human brain structure and function Alexander-Bloch, AF; Shou, H; Liu, S et al. Neuroimage, DOI://10.1016/j.neuroimage.2018.05.070 (2018)
Predictors of mosaic chromosome Y loss and associations with mortality in the UK Biobank Loftfield, E; Zhou, W; Graubard, BI et al. Sci Rep, DOI://10.1038/s41598-018-30759-1 (2018)

Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs Matthies, D; Bae, C; Toombes, GE et al. Elife, DOI://10.7554/eLife.37558 (2018)
A DNA methylation biomarker of alcohol consumption Liu, C; Marioni, RE; Hedman, ÅK et al. Mol. Psychiatry, DOI://10.1038/mp.2016.192 (2018)
Targeting the HTLV-I-Regulated BATF3/IRF4 Transcriptional Network in Adult T Cell Leukemia/Lymphoma Nakagawa, M; Shaffer, AL; Ceribelli, M et al. Cancer Cell, DOI://10.1016/j.ccell.2018.06.014 (2018)
Feasibility and accuracy of UF/NCI phantoms and Monte Carlo retrospective dosimetry in children treated on National Wilms Tumor Study protocols Kalapurakal, JA; Gopalakrishnan, M; Mille, M et al. Pediatr Blood Cancer, DOI://10.1002/pbc.27395 (2018)
Structure and energetic basis of overrepresented λ light chain in systemic light chain amyloidosis patients Zhao, J; Zhang, B; Zhu, J; Nussinov, R; Ma, B; Biochim. Biophys. Acta, DOI://10.1016/j.bbadis.2017.12.009 (2018)
Allosteric KRas4B Can Modulate SOS1 Fast and Slow Ras Activation Cycles Liao, TJ; Jang, H; Fushman, D; Nussinov, R; Biophys. J., DOI://10.1016/j.bpj.2018.07.016 (2018)

A coevolution-guided model for the rotor of the bacterial flagellar motor Khan, S; Guo, TW; Misra, S; Sci Rep, DOI://10.1038/s41598-018-30293-0 (2018)
A Muscle-Specific Enhancer RNA Mediates Cohesin Recruitment and Regulates Transcription In trans Tsai, PF; Dell'Orso, S; Rodriguez, J et al. Mol. Cell, DOI://10.1016/j.molcel.2018.06.008 (2018)
Effects of Human Sex Chromosome Dosage on Spatial Chromosome Organization Jowhar, Z; Shachar, S; Gudla, PR et al. Mol. Biol. Cell, DOI://10.1091/mbc.E18-06-0359 (2018)
Reliably picking the best endpoint Follmann, D Stat Med, DOI://10.1002/sim.7927 (2018)
A multiprotein supercomplex controlling oncogenic signalling in lymphoma Phelan, JD; Young, RM; Webster, DE et al. Nature, DOI://10.1038/s41586-018-0290-0 (2018)
Glutamatergic Signaling Drives Ketamine-Mediated Response in Depression: Evidence from Dynamic Causal Modeling Gilbert, JR; Yarrington, JS; Wills, KE; Nugent, AC; Zarate, CA; Int. J. Neuropsychopharmacol., DOI://10.1093/ijnp/pyy041 (2018)

Re-analysis of Whole Genome Sequence Data From 279 Ancient Eurasians Reveals Substantial Ancestral Heterogeneity Shriner, D Front Genet, DOI://10.3389/fgene.2018.00268 (2018)
Association of Coffee Drinking With Mortality by Genetic Variation in Caffeine Metabolism: Findings From the UK Biobank Loftfield, E; Cornelis, MC; Caporaso, N; Yu, K; Sinha, R; Freedman, N; JAMA Intern Med, DOI://10.1001/jamainternmed.2018.2425 (2018)
Cone-rod homeobox CRX controls presynaptic active zone formation in photoreceptors of mammalian retina Assawachananont, J; Kim, SY; Kaya, KD; Fariss, R; Roger, JE; Swaroop, A; Hum. Mol. Genet., DOI://10.1093/hmg/ddy272 (2018)
Prediction of CB[8] host-guest binding free energies in SAMPL6 using the double-decoupling method Han, K; Hudson, PS; Jones, MR; Nishikawa, N; Tofoleanu, F; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-018-0144-8 (2018)
ATAC2GRN: optimized ATAC-seq and DNase1-seq pipelines for rapid and accurate genome regulatory network inference Pranzatelli, TJF; Michael, DG; Chiorini, JA; BMC Genomics, DOI://10.1186/s12864-018-4943-z (2018)
Modelling the structure of a ceRNA-theoretical, bipartite microRNA-mRNA interaction network regulating intestinal epithelial cellular pathways using R programming Robinson, JM; Henderson, WA; BMC Res Notes, DOI://10.1186/s13104-018-3126-y (2018)

Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse Tubbs, A; Sridharan, S; van Wietmarschen, N et al. Cell, DOI://10.1016/j.cell.2018.07.011 (2018)
Presynaptic Inhibition Selectively Gates Auditory Transmission to the Brainstem Startle Circuit Tabor, KM; Smith, TS; Brown, M; Bergeron, SA; Briggman, KL; Burgess, HA; Curr. Biol., DOI://10.1016/j.cub.2018.06.020 (2018)
Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points Heuston, EF; Keller, CA; Lichtenberg, J et al. Epigenetics Chromatin, DOI://10.1186/s13072-018-0195-z (2018)
Decoding microglia responses to psychosocial stress reveals blood-brain barrier breakdown that may drive stress susceptibility Lehmann, ML; Weigel, TK; Cooper, HA; Elkahloun, AG; Kigar, SL; Herkenham, M; Sci Rep, DOI://10.1038/s41598-018-28737-8 (2018)
A Fast Approximate Algorithm for Mapping Long Reads to Large Reference Databases Jain, C; Dilthey, A; Koren, S; Aluru, S; Phillippy, AM; J. Comput. Biol., DOI://10.1089/cmb.2018.0036 (2018)
Cryo-EM of the dynamin polymer assembled on lipid membrane Kong, L; Sochacki, KA; Wang, H et al. Nature, DOI://10.1038/s41586-018-0378-6 (2018)

Dual Roles for Ikaros in Regulation of Macrophage Chromatin State and Inflammatory Gene Expression Oh, KS; Gottschalk, RA; Lounsbury, NW et al. J. Immunol., DOI://10.4049/jimmunol.1800158 (2018)
Genetic selection of athletic success in sport-hunting dogs Kim, J; Williams, FJ; Dreger, DL et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1800455115 (2018)
NLM at ImageCLEF 2018 Visual Question Answering in the Medical Domain Asma Ben Abacha, Soumya Gayen, Jason J Lau, Sivaramakrishnan Rajaraman, and Dina Demner-Fushman ImageCLEF 2018 (2018)
Scalable Biomedical Image Synthesis with GAN Canas, K; Ubiera, B; Liu, X; Liu Y Proceedings of the Practice and Experience on Advanced Research Computing Article No. 95 , doi://10.1145/3219104.3229261 (2018)
The Energetics and Physiological Impact of Cohesin Extrusion Vian, L; Pekowska, A; Rao, SSP et al. Cell, DOI://10.1016/j.cell.2018.03.072 (2018)
Transcriptional signature primes human oral mucosa for rapid wound healing Iglesias-Bartolome, R; Uchiyama, A; Molinolo, AA et al. Sci Transl Med, DOI://10.1126/scitranslmed.aap8798 (2018)
Efficient experimental designs for isotropic generalized diffusion tensor MRI (IGDTI) Avram, AV; Sarlls, JE; Hutchinson, E; Basser, PJ; Magn Reson Med, DOI://10.1002/mrm.26656 (2018)
Circulating cell-free DNA as a biomarker of tissue injury: Assessment in a cardiac xenotransplantation model Agbor-Enoh, S; Chan, JL; Singh, A et al. J. Heart Lung Transplant., DOI://10.1016/j.healun.2018.04.009 (2018)
PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity van Setten, J; Brody, JA; Jamshidi, Y et al. Nat Commun, DOI://10.1038/s41467-018-04766-9 (2018)
Patient iPSC-derived neural stem cells exhibit phenotypes in concordance with the clinical severity of Mucopolysaccharidosis I Swaroop, M; Brooks, MJ; Gieser, L; Swaroop, A; Zheng, W; Hum. Mol. Genet., DOI://10.1093/hmg/ddy259 (2018)
Genetic diversity of noroviruses circulating in a pediatric cohort in Bangladesh Nelson, MI; Mahfuz, M; Chhabra, P et al. J. Infect. Dis., DOI://10.1093/infdis/jiy454 (2018)
Role of gamma-amino-butyric acid in the dorsal anterior cingulate in age-associated changes in cognition Marenco, S; Meyer, C; van der Veen, JW et al. Neuropsychopharmacology, DOI://10.1038/s41386-018-0134-5 (2018)

Reliability of neural activation and connectivity during implicit face emotion processing in youth Haller, SP; Kircanski, K; Stoddard, J et al. Dev Cogn Neurosci, DOI://10.1016/j.dcn.2018.03.010 (2018)
Frequency of Loss of Function Variants in LRRK2 in Parkinson Disease Blauwendraat, C; Reed, X; Kia, DA et al. JAMA Neurol, DOI://10.1001/jamaneurol.2018.1885 (2018)
ADAM17-Deficient Mice Model the Transcriptional Signature of Human Atopic Dermatitis Woodring, T; Kobayashi, T; Kim, D; Nagao, K; J. Invest. Dermatol., DOI://10.1016/j.jid.2018.04.021 (2018)
Anionic Phospholipids Bind to and Modulate the Activity of Human TRESK Background K+ Channel Giblin, JP; Etayo, I; Castellanos, A; Andres-Bilbe, A; Gasull, X; Mol. Neurobiol., DOI://10.1007/s12035-018-1244-0 (2018)
7 T MRI reveals hippocampal structural abnormalities associated with memory intrusions in childhood-onset schizophrenia Zhou, D; Liu, S; Zhou, X et al. Schizophr. Res., DOI://10.1016/j.schres.2018.07.023 (2018)
BMX-mediated regulation of multiple tyrosine kinases contributes to castration resistance in prostate cancer Chen, S; Cai, C; Sowalsky, AG et al. Cancer Res., DOI://10.1158/0008-5472.CAN-17-3615 (2018)
Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits Haljas, K; Amare, AT; Alizadeh, BZ et al. Psychosom Med, DOI://10.1097/PSY.0000000000000555 (2018)
Hepatitis B virus deregulates cell cycle to promote viral replication and a premalignant phenotype Xia, Y; Cheng, X; Li, Y; Valdez, K; Chen, W; Liang, TJ; J. Virol., DOI://10.1128/JVI.00722-18 (2018)
PfCDPK1 is critical for malaria parasite gametogenesis and mosquito infection Bansal, A; Molina-Cruz, A; Brzostowski, J et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1715443115 (2018)
The major depressive disorder GWAS-supported variant rs10514299 in TMEM161B-MEF2C predicts putamen activation during reward processing in alcohol dependence Muench, C; Schwandt, M; Jung, J; Cortes, CR; Momenan, R; Lohoff, FW; Transl Psychiatry, DOI://10.1038/s41398-018-0184-9 (2018)
Whole Blood Gene Expression Associated with Clinical Biological Age Lin, H; Lunetta, KL; Zhao, Q et al. J. Gerontol. A Biol. Sci. Med. Sci., DOI://10.1093/gerona/gly164 (2018)
Ultra-high resolution blood volume fMRI and BOLD fMRI in humans at 9.4 T: Capabilities and challenges Huber, L; Tse, DHY; Wiggins, CJ et al. Neuroimage, DOI://10.1016/j.neuroimage.2018.06.025 (2018)
Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent Smith, CE; Follis, JL; Dashti, HS et al. Mol Nutr Food Res, DOI://10.1002/mnfr.201700347 (2018)
Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas Campbell, JD; Yau, C; Bowlby, R et al. Cell Rep, DOI://10.1016/j.celrep.2018.03.063 (2018)
Structural analysis of influenza vaccine virus-like particles reveals a multicomponent organization McCraw, DM; Gallagher, JR; Torian, U et al. Sci Rep, DOI://10.1038/s41598-018-28700-7 (2018)
Postnatal developmental dynamics of cell type specification genes in Brn3a/Pou4f1 Retinal Ganglion Cells Muzyka, VV; Brooks, M; Badea, TC; Neural Dev, DOI://10.1186/s13064-018-0110-0 (2018)
Deep-learning-assisted Volume Visualization Cheng, HC; Cardone, A; Jain, S et al. IEEE Trans Vis Comput Graph, DOI://10.1109/TVCG.2018.2796085 (2018)
The Sleep Inbred Panel, a Collection of Inbred Drosophila melanogaster with Extreme Long and Short Sleep Duration Serrano Negron, YL; Hansen, NF; Harbison, ST; G3 (Bethesda), DOI://10.1534/g3.118.200503 (2018)

A feasibility study to reduce misclassification error in occupational dose estimates for epidemiological studies using body size-dependent computational phantoms Sarah Kim, Lienard Chang, Elizabeth Mosher, Choonik Lee, and Choonsik IEEE Transactions on Radiation and Plasma Medical Sciences, 0.1109/TRPMS.2018.2847227 (2018)
Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium Merino, J; Dashti, HS; Li, SX et al. Mol. Psychiatry, DOI://10.1038/s41380-018-0079-4 (2018)
Investigation of the seasonal microbiome of Anopheles coluzzii mosquitoes in Mali Krajacich, BJ; Huestis, DL; Dao, A et al. PLoS ONE, DOI://10.1371/journal.pone.0194899 (2018)
Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair Linehan, JL; Harrison, OJ; Han, SJ et al. Cell, DOI://10.1016/j.cell.2017.12.033 (2018)
Influence of gut microbiome on mucosal immune activation and SHIV viral transmission in naive macaques Sui, Y; Dzutsev, A; Venzon, D et al. Mucosal Immunol, DOI://10.1038/s41385-018-0029-0 (2018)
Building Blocks of the Outer Membrane: Calculating a general elastic energy model for β-barrel membrane proteins Lessen, HJ; Fleming, PJ; Fleming, KG; Sodt, AJ; J Chem Theory Comput, DOI://10.1021/acs.jctc.8b00377 (2018)

Strand-specific Dual RNA-seq of Bronchial Epithelial cells Infected with Influenza A/H3N2 Viruses Reveals Splicing of Gene Segment 6 and Novel Host-Virus Interactions Fabozzi, G; Oler, AJ; Liu, P et al. J. Virol., DOI://10.1128/JVI.00518-18 (2018)
Visualizing Deep Learning Activations for Improved Malaria Cell Classification Rajaraman S, Antani SK, Jaeger S Proceedings of Machine Learning Research (PMLR), v69, p40-47 (2018)
Comparing deep learning models for population screening using chest radiography Rajaraman S, Antani SK, Candemir S, Xue Z, Abuya J, Kohli M, Alderson P, Thoma GR Proc. SPIE 10575, Medical Imaging 2018: Computer-Aided Diagn (2018)
The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma Ricketts, CJ; De Cubas, AA; Fan, H et al. Cell Rep, DOI://10.1016/j.celrep.2018.06.032 (2018)
NCR+ ILC3 maintain larger STAT4 reservoir via T-BET to regulate type 1 features upon IL-23 stimulation in mice Mikami, Y; Scarno, G; Zitti, B et al. Eur. J. Immunol., DOI://10.1002/eji.201847480 (2018)
Parameterization of the CHARMM All-Atom Force Field for Ether Lipids and Model Linear Ethers Leonard, AN; Pastor, RW; Klauda, JB; J Phys Chem B, DOI://10.1021/acs.jpcb.8b02743 (2018)
MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma Yohe, ME; Gryder, BE; Shern, JF et al. Sci Transl Med, DOI://10.1126/scitranslmed.aan4470 (2018)
Integrative Bayesian Analysis Identifies Rhabdomyosarcoma Disease Genes Xu, L; Zheng, Y; Liu, J et al. Cell Rep, DOI://10.1016/j.celrep.2018.06.006 (2018)
Geographic clonal tracking in macaques provides insights into HSPC migration and differentiation Wu, C; Espinoza, DA; Koelle, SJ et al. J. Exp. Med., DOI://10.1084/jem.20171341 (2018)
An epigenetic mechanism for cavefish eye degeneration Gore, AV; Tomins, KA; Iben, J et al. Nat Ecol Evol, DOI://10.1038/s41559-018-0569-4 (2018)
N-Myc Downstream-Regulated Gene 1 Restricts Hepatitis C Virus Propagation by Regulating Lipid Droplet Biogenesis and Viral Assembly Schweitzer, CJ; Zhang, F; Boyer, A; Valdez, K; Cam, M; Liang, TJ; J. Virol., DOI://10.1128/JVI.01166-17 (2018)
Arl2-Mediated Allosteric Release of Farnesylated KRas4B from Shuttling Factor PDEδ Ozdemir, ES; Jang, H; Gursoy, A; Keskin, O; Nussinov, R; J Phys Chem B, DOI://10.1021/acs.jpcb.8b04347 (2018)

Defects in the Alternative Splicing-Dependent Regulation of REST Cause Deafness Nakano, Y; Kelly, MC; Rehman, AU et al. Cell, DOI://10.1016/j.cell.2018.06.004 (2018)
Targeting Notch1 and IKKa enhanced NF-κB activation in CD133+ Skin Cancer Stem Cells Quan, XX; Voong Hawk, N; Chen, W et al. Mol. Cancer Ther., DOI://10.1158/1535-7163.MCT-17-0421 (2018)
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein Kang, Y; Kuybeda, O; de Waal, PW et al. Nature, DOI://10.1038/s41586-018-0215-y (2018)
An Autonomic Network: Synchrony Between Slow Rhythms of Pulse and Brain Resting State Is Associated with Personality and Emotions Shokri-Kojori, E; Tomasi, D; Volkow, ND; Cereb. Cortex, DOI://10.1093/cercor/bhy144 (2018)
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries Feitosa, MF; Kraja, AT; Chasman, DI et al. PLoS ONE, DOI://10.1371/journal.pone.0198166 (2018)
Tightly Integrated Genomic and Epigenomic Data Mining Using Tensor Decomposition Fang, J Bioinformatics, DOI://10.1093/bioinformatics/bty513 (2018)

Morphometric analysis and neuroanatomical mapping of the zebrafish brain Gupta, T; Marquart, GD; Horstick, EJ; Tabor, KM; Pajevic, S; Burgess, HA; Methods, DOI://10.1016/j.ymeth.2018.06.008 (2018)
Guide RNA selection for CRISPR-Cas9 transfections in Plasmodium falciparum Ribeiro, JM; Garriga, M; Potchen, N et al. Int. J. Parasitol., DOI://10.1016/j.ijpara.2018.03.009 (2018)
Neoadjuvant-intensive androgen deprivation therapy selects for prostate tumor foci with diverse subclonal oncogenic alterations Sowalsky, AG; Ye, H; Bhasin, M et al. Cancer Res., DOI://10.1158/0008-5472.CAN-18-0610 (2018)
Late manifestation of alloantibody-associated injury and clinical pulmonary antibody-mediated rejection: Evidence from cell-free DNA analysis Agbor-Enoh, S; Jackson, AM; Tunc, I et al. J. Heart Lung Transplant., DOI://10.1016/j.healun.2018.01.1305 (2018)
A subregion-based burden test for simultaneous identification of susceptibility loci and subregions within Zhu, B; Mirabello, L; Chatterjee, N; Genet. Epidemiol., DOI://10.1002/gepi.22134 (2018)
HPV integration hijacks and multimerizes a cellular enhancer to generate a viral-cellular super-enhancer that drives high viral oncogene expression Warburton, A; Redmond, CJ; Dooley, KE et al. PLoS Genet., DOI://10.1371/journal.pgen.1007179 (2018)
Publisher Correction: Cryo-EM structure of human rhodopsin bound to an inhibitory G protein Kang, Y; Kuybeda, O; de Waal, PW et al. Nature, DOI://10.1038/s41586-018-0302-0 (2018)
Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma Schmitz, R; Wright, GW; Huang, DW et al. N. Engl. J. Med., DOI://10.1056/NEJMoa1801445 (2018)
ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming Mishra, P; Tang, W; Putluri, V et al. J. Clin. Invest., DOI://10.1172/JCI93815 (2018)
Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay Duverger, O; Carlson, JC; Karacz, CM et al. PLoS Genet., DOI://10.1371/journal.pgen.1007168 (2018)
Innate and adaptive lymphocytes sequentially shape the gut microbiota and lipid metabolism Mao, K; Baptista, AP; Tamoutounour, S et al. Nature, DOI://10.1038/nature25437 (2018)
Normative brain size variation and brain shape diversity in humans Reardon, PK; Seidlitz, J; Vandekar, S et al. Science, DOI://10.1126/science.aar2578 (2018)
Microbiology catches the cryo-EM bug Earl, LA; Falconieri, V; Subramaniam, S; Curr. Opin. Microbiol., DOI://10.1016/j.mib.2018.02.012 (2018)
RiboSketch: Versatile Visualization of Multi-stranded RNA and DNA Secondary Structure Lu, JS; Bindewald, E; Kasprzak, W; Shapiro, BA; Bioinformatics, DOI://10.1093/bioinformatics/bty468 (2018)
Sialome diversity of ticks revealed by RNAseq of single tick salivary glands Perner, J; Kropáčková, S; Kopáček, P; Ribeiro, JMC; PLoS Negl Trop Dis, DOI://10.1371/journal.pntd.0006410 (2018)
Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density Alonso, N; Estrada, K; Albagha, OME et al. Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2017-212469 (2018)
Structure-Guided Modification of Heterocyclic Antagonists of the P2Y14 Receptor Yu, J; Ciancetta, A; Dudas, S; Duca, S; Lottermoser, J; Jacobson, KA; J. Med. Chem., DOI://10.1021/acs.jmedchem.8b00168 (2018)
A coupled-clock system drives the automaticity of human sinoatrial nodal pacemaker cells Tsutsui, K; Monfredi, OJ; Sirenko-Tagirova, SG et al. Sci Signal, DOI://10.1126/scisignal.aap7608 (2018)

The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma McBride, MJ; Pulice, JL; Beird, HC et al. Cancer Cell, DOI://10.1016/j.ccell.2018.05.002 (2018)
AptaSUITE: A Full-Featured Bioinformatics Framework for the Comprehensive Analysis of Aptamers from HT-SELEX Experiments Hoinka, J; Backofen, R; Przytycka, TM; Mol Ther Nucleic Acids, DOI://10.1016/j.omtn.2018.04.006 (2018)
Modifier locus mapping of a transgenic F2 mouse population identifies CCDC115 as a novel aggressive prostate cancer modifier gene in humans Winter, JM; Curry, NL; Gildea, DM et al. BMC Genomics, DOI://10.1186/s12864-018-4827-2 (2018)
Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers Hodges, HC; Stanton, BZ; Cermakova, K et al. Nat. Struct. Mol. Biol., DOI://10.1038/s41594-017-0007-3 (2018)
Exploring Substrate Binding in the Extracellular Vestibule of MhsT by Atomistic Simulations and Markov Models Abramyan, AM; Quick, M; Xue, C; Javitch, JA; Shi, L; J Chem Inf Model, DOI://10.1021/acs.jcim.8b00175 (2018)
HiCTMap: Detection and analysis of chromosome territory structure and position by high-throughput imaging Jowhar, Z; Gudla, PR; Shachar, S et al. Methods, DOI://10.1016/j.ymeth.2018.01.013 (2018)
Chromatic: WebAssembly-Based Cancer Genome Viewer Finney, R; Meerzaman, D; Cancer Inform, DOI://10.1177/1176935118771972 (2018)
DNA Methylation and Regulatory Elements during Chicken Germline Stem Cell Differentiation He, Y; Zuo, Q; Edwards, J et al. Stem Cell Reports, DOI://10.1016/j.stemcr.2018.03.018 (2018)
Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer Zacharakis, N; Chinnasamy, H; Black, M et al. Nat. Med., DOI://10.1038/s41591-018-0040-8 (2018)
Cracking the DNA Code for V(D)J Recombination Kim, MS; Chuenchor, W; Chen, X et al. Mol. Cell, DOI://10.1016/j.molcel.2018.03.008 (2018)
Evaluation and comparison of predictive individual-level general surrogates Gabriel, EE; Sachs, MC; Halloran, ME; Biostatistics, DOI://10.1093/biostatistics/kxx037 (2018)
DLX3-Dependent STAT3 Signaling in Keratinocytes Regulates Skin Immune Homeostasis Bhattacharya, S; Kim, JC; Ogawa, Y et al. J. Invest. Dermatol., DOI://10.1016/j.jid.2017.11.033 (2018)

Rapid Classification and Identification of Multiple Microorganisms with Accurate Statistical Significance via High-Resolution Tandem Mass Spectrometry Alves, G; Wang, G; Ogurtsov, AY et al. J. Am. Soc. Mass Spectrom., DOI://10.1007/s13361-018-1986-y (2018)
Emergence and Evolution of Novel Reassortant Influenza A Viruses in Canines in Southern China Chen, Y; Trovão, NS; Wang, G et al. MBio, DOI://10.1128/mBio.00909-18 (2018)
Multivalent Display Using Hybrid Virus Nanoparticles Brown, SD Methods Mol. Biol., DOI://10.1007/978-1-4939-7893-9_10 (2018)
In-depth investigations of adolescents and adults with holoprosencephaly identify unique characteristics Weiss, K; Kruszka, P; Guillen Sacoto, MJ et al. Genet. Med., DOI://10.1038/gim.2017.68 (2018)
Correction: Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations Liang, J; Le, TH; Velez Edwards, DR et al. PLoS Genet., DOI://10.1371/journal.pgen.1007345 (2018)
Genome-Wide Mapping of DNA Accessibility and Binding Sites for CREB and C/EBPβ in Vasopressin-Sensitive Collecting Duct Cells Jung, HJ; Raghuram, V; Lee, JW; Knepper, MA; J. Am. Soc. Nephrol., DOI://10.1681/ASN.2017050545 (2018)

Discovering a binary CTCF code with a little help from BORIS Lobanenkov, VV; Zentner, GE; Nucleus, DOI://10.1080/19491034.2017.1394536 (2018)
T-cell responses to TP53 "hotspot" mutations and unique neoantigens expressed by human ovarian cancers Deniger, DC; Pasetto, A; Robbins, PF et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-0573 (2018)
Computational Modeling of Mitochondrial Function from a Systems Biology Perspective Cortassa, S; Sollott, SJ; Aon, MA; Methods Mol. Biol., DOI://10.1007/978-1-4939-7831-1_14 (2018)
Trait paranoia shapes inter-subject synchrony in brain activity during an ambiguous social narrative Finn, ES; Corlett, PR; Chen, G; Bandettini, PA; Constable, RT; Nat Commun, DOI://10.1038/s41467-018-04387-2 (2018)
High burden of birthweight-lowering genetic variants in Africans and Asians Tekola-Ayele, F; Workalemahu, T; Amare, AT; BMC Med, DOI://10.1186/s12916-018-1061-3 (2018)
SWI/SNF and RSC cooperate to reposition and evict promoter nucleosomes at highly expressed genes in yeast Rawal, Y; Chereji, RV; Qiu, H et al. Genes Dev., DOI://10.1101/gad.312850.118 (2018)

Comparative Population Genomics Analysis of the Mammalian Fungal Pathogen Pneumocystis Cissé, OH; Ma, L; Wei Huang, D et al. MBio, DOI://10.1128/mBio.00381-18 (2018)
Characterization of Hemagglutinin Antigens on Influenza Virus and within Vaccines Using Electron Microscopy Gallagher, JR; McCraw, DM; Torian, U et al. Vaccines (Basel), DOI://10.3390/vaccines6020031 (2018)
Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence Vera-Ramirez, L; Vodnala, SK; Nini, R; Hunter, KW; Green, JE; Nat Commun, DOI://10.1038/s41467-018-04070-6 (2018)
Mapping the neuroanatomic substrates of cognition in familial attention deficit hyperactivity disorder Muster, R; Choudhury, S; Sharp, W; Kasparek, S; Sudre, G; Shaw, P; Psychol Med, DOI://10.1017/S0033291718001241 (2018)
Variation in human chromosome 21 ribosomal RNA genes characterized by TAR cloning and long-read sequencing Kim, JH; Dilthey, AT; Nagaraja, R et al. Nucleic Acids Res., DOI://10.1093/nar/gky442 (2018)
Clinically Relevant Cytotoxic Immune Cell Signatures and Clonal Expansion of T-Cell Receptors in High-risk MYCN-not-amplified Human Neuroblastoma Wei, JS; Kuznetsov, IB; Zhang, S et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-0599 (2018)
Functional screening of FGFR4-driven tumorigenesis identifies PI3K/mTOR inhibition as a therapeutic strategy in rhabdomyosarcoma McKinnon, T; Venier, R; Yohe, M et al. Oncogene, DOI://10.1038/s41388-017-0122-y (2018)
Graph-Theoretic Analysis of Monomethyl Phosphate Clustering in Ionic Solutions Han, K; Venable, RM; Bryant, AM et al. J Phys Chem B, DOI://10.1021/acs.jpcb.7b10730 (2018)
Atomic Resolution Cryo-EM Structure of β-Galactosidase Bartesaghi, A; Aguerrebere, C; Falconieri, V et al. Structure, DOI://10.1016/j.str.2018.04.004 (2018)
Identification of Novel Targets for Lung Cancer Therapy Using an Induced Pluripotent Stem Cell Model Shukla, V; Rao, M; Zhang, H et al. Ann Am Thorac Soc, DOI://10.1513/AnnalsATS.201707-610MG (2018)
The distinct structural preferences of tau protein repeat domains Li, X; Dong, X; Wei, G; Margittai, M; Nussinov, R; Ma, B; Chem. Commun. (Camb.), DOI://10.1039/c8cc01263f (2018)
Neutrophil subsets and their gene signature associate with vascular inflammation and coronary atherosclerosis in lupus Carlucci, PM; Purmalek, MM; Dey, AK et al. JCI Insight, DOI://10.1172/jci.insight.99276 (2018)

Molecular dynamics simulations of lipid nanodiscs Pourmousa, M; Pastor, RW; Biochim. Biophys. Acta, DOI://10.1016/j.bbamem.2018.04.015 (2018)
Epigenome-Wide Association Study of Soluble Tumor Necrosis Factor Receptor 2 Levels in the Framingham Heart Study Mendelson, MM; Johannes, R; Liu, C et al. Front Pharmacol, DOI://10.3389/fphar.2018.00207 (2018)
Experimental and Computational Protocols for Studies of Cross-Seeding Amyloid Assemblies Ren, B; Hu, R; Zhang, M et al. Methods Mol. Biol., DOI://10.1007/978-1-4939-7811-3_27 (2018)
Replica Exchange Molecular Dynamics: A Practical Application Protocol with Solutions to Common Problems and a Peptide Aggregation and Self-Assembly Example Qi, R; Wei, G; Ma, B; Nussinov, R; Methods Mol. Biol., DOI://10.1007/978-1-4939-7811-3_5 (2018)
Dynamic Behavior of RNA Nanoparticles Analyzed by AFM on a Mica/Air Interface Sajja, S; Chandler, M; Fedorov, D et al. Langmuir, DOI://10.1021/acs.langmuir.8b00105 (2018)
iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications Ou, J; Ball, JM; Luan, Y et al. Cell, DOI://10.1016/j.cell.2018.03.010 (2018)

Germline gain-of-function myeloid differentiation primary response gene-88 (MYD88) mutation in a child with severe arthritis Sikora, KA; Bennett, JR; Vyncke, L et al. J. Allergy Clin. Immunol., DOI://10.1016/j.jaci.2018.01.027 (2018)
Iron homeostasis regulates facultative heterochromatin assembly in adaptive genome control Gallagher, PS; Larkin, M; Thillainadesan, G et al. Nat. Struct. Mol. Biol., DOI://10.1038/s41594-018-0056-2 (2018)
Whole-Exome Sequencing to Identify Rare Variants and Gene Networks That Increase Susceptibility to Scleroderma in African Americans Gourh, P; Remmers, EF; Boyden, SE et al. , DOI://10.1002/art.40541 (2018)
Irritability Trajectories, Cortical Thickness, and Clinical Outcomes in a Sample Enriched for Preschool Depression Pagliaccio, D; Pine, DS; Barch, DM; Luby, JL; Leibenluft, E; J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2018.02.010 (2018)
Temporal Variability of Oral Microbiota over 10 Months and the Implications for Future Epidemiologic Studies Vogtmann, E; Hua, X; Zhou, L et al. Cancer Epidemiol. Biomarkers Prev., DOI://10.1158/1055-9965.EPI-17-1004 (2018)
Position-specific intron retention is mediated by the histone methyltransferase SDG725 Wei, G; Liu, K; Shen, T et al. BMC Biol., DOI://10.1186/s12915-018-0513-8 (2018)

Day length is associated with physical activity and sedentary behavior among older women Schepps, MA; Shiroma, EJ; Kamada, M; Harris, TB; Lee, IM; Sci Rep, DOI://10.1038/s41598-018-25145-w (2018)
Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group Hibar, DP; Westlye, LT; Doan, NT et al. Mol. Psychiatry, DOI://10.1038/mp.2017.73 (2018)
A draft genome sequence for the Ixodes scapularis cell line, ISE6 Miller, JR; Koren, S; Dilley, KA et al. F1000Res, DOI://10.12688/f1000research.13635.1 (2018)
Insulin promoter in human pancreatic β cells contacts diabetes susceptibility loci and regulates genes affecting insulin metabolism Jian, X; Felsenfeld, G; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1803146115 (2018)
Organization of the core respiratory network: Insights from optogenetic and modeling studies Ausborn, J; Koizumi, H; Barnett, WH et al. PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1006148 (2018)
Dealing with competing risks in clinical trials: How to choose the primary efficacy analysis Troendle, JF; Leifer, ES; Kunz, L; Stat Med, DOI://10.1002/sim.7800 (2018)

A cleavage product of Polycystin-1 is a mitochondrial matrix protein that affects mitochondria morphology and function when heterologously expressed Lin, CC; Kurashige, M; Liu, Y et al. Sci Rep, DOI://10.1038/s41598-018-20856-6 (2018)
SIRT1 is a transcriptional enhancer of the glucocorticoid receptor acting independently to its deacetylase activity Suzuki, S; Iben, JR; Coon, SL; Kino, T; Mol. Cell. Endocrinol., DOI://10.1016/j.mce.2017.09.012 (2018)
Massively Parallel Single Nucleus Transcriptional Profiling Defines Spinal Cord Neurons and Their Activity during Behavior Sathyamurthy, A; Johnson, KR; Matson, KJE et al. Cell Rep, DOI://10.1016/j.celrep.2018.02.003 (2018)
A mutational comparison of adult and adolescent and young adult (AYA) colon cancer Tricoli, JV; Boardman, LA; Patidar, R et al. Cancer, DOI://10.1002/cncr.31136 (2018)
Insufficient evidence for pathogenicity of SNCA His50Gln (H50Q) in Parkinson's disease Blauwendraat, C; Kia, DA; Pihlstrøm, L et al. Neurobiol. Aging, DOI://10.1016/j.neurobiolaging.2017.12.012 (2018)
Comprehensive Synthesis of Amino Acid-Derived Thiazole Peptidomimetic Analogues to Understand the Enigmatic Drug/Substrate-Binding Site of P-Glycoprotein Patel, BA; Abel, B; Barbuti, AM et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.7b01340 (2018)

Homeobox transcription factor DLX4 is not necessary for skin development and homeostasis Bhattacharya, S; Duverger, O; Brooks, SR; Morasso, MI; Exp. Dermatol., DOI://10.1111/exd.13503 (2018)
Outcomes of Children and Adolescents with Advanced Hereditary Medullary Thyroid Carcinoma Treated with Vandetanib Kraft, IL; Akshintala, S; Zhu, Y et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-17-2101 (2018)
Feedforward Inhibition Allows Input Summation to Vary in Recurrent Cortical Networks Histed, MH eNeuro, DOI://10.1523/ENEURO.0356-17.2018 (2018)
Effects on gene expression and behavior of untagged short tandem repeats: the case of arginine vasopressin receptor 1a (AVPR1a) and externalizing behaviors Landefeld, CC; Hodgkinson, CA; Spagnolo, PA et al. Transl Psychiatry, DOI://10.1038/s41398-018-0120-z (2018)
Morphometric Similarity Networks Detect Microscale Cortical Organization and Predict Inter-Individual Cognitive Variation Seidlitz, J; Váša, F; Shinn, M et al. Neuron, DOI://10.1016/j.neuron.2017.11.039 (2018)
A multicohort, longitudinal study of cerebellar development in attention deficit hyperactivity disorder Shaw, P; Ishii-Takahashi, A; Park, MT et al. J Child Psychol Psychiatry, DOI://10.1111/jcpp.12920 (2018)

Single-tubule RNA-Seq uncovers signaling mechanisms that defend against hyponatremia in SIADH Lee, JW; Alsady, M; Chou, CL et al. Kidney Int., DOI://10.1016/j.kint.2017.06.008 (2018)
Interrogating the Functions of PRDM9 Domains in Meiosis Thibault-Sennett, S; Yu, Q; Smagulova, F et al. Genetics, DOI://10.1534/genetics.118.300565 (2018)
Using standard microbiome reference groups to simplify beta-diversity analyses and facilitate independent validation Maziarz, M; Pfeiffer, RM; Wan, Y; Gail, MH; Bioinformatics, DOI://10.1093/bioinformatics/bty297 (2018)
Electrophysiological heterogeneity of pacemaker cells in the rabbit intercaval region, including the SA node: insights from recording multiple ion currents in each cell Monfredi, O; Tsutsui, K; Ziman, B; Stern, MD; Lakatta, EG; Maltsev, VA; Am. J. Physiol. Heart Circ. Physiol., DOI://10.1152/ajpheart.00253.2016 (2018)
Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors Giannelou, A; Wang, H; Zhou, Q et al. Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2017-212401 (2018)
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay Baird, TD; Cheng, KC; Chen, YC et al. Elife, DOI://10.7554/eLife.33178 (2018)

A joint spatial factor analysis model to accommodate data from misaligned areal units with application to Louisiana social vulnerability Nethery, RC; Sandler, DP; Zhao, S; Engel, LS; Kwok, RK; Biostatistics, DOI://10.1093/biostatistics/kxy016 (2018)
Somatic activating mutations in MAP2K1 cause melorheostosis Kang, H; Jha, S; Deng, Z et al. Nat Commun, DOI://10.1038/s41467-018-03720-z (2018)
Analysis of the 9p21.3 sequence associated with coronary artery disease reveals a tendency for duplication in a CAD patient Kouprina, N; Liskovykh, M; Lee, NCO et al. Oncotarget, DOI://10.18632/oncotarget.24567 (2018)
Characterization of clinically used oral antiseptics as quadruplex-binding ligands Calabrese, DR; Zlotkowski, K; Alden, S et al. Nucleic Acids Res., DOI://10.1093/nar/gky084 (2018)
A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope Zhou, T; Zheng, A; Baxa, U et al. Immunity, DOI://10.1016/j.immuni.2018.02.013 (2018)
Statistical power comparisons at 3T and 7T with a GO / NOGO task Torrisi, S; Chen, G; Glen, D et al. Neuroimage, DOI://10.1016/j.neuroimage.2018.03.071 (2018)

Gcn4 Binding in Coding Regions Can Activate Internal and Canonical 5' Promoters in Yeast Rawal, Y; Chereji, RV; Valabhoju, V et al. Mol. Cell, DOI://10.1016/j.molcel.2018.03.007 (2018)
Deep sequencing of the mitochondrial genome reveals common heteroplasmic sites in NADH dehydrogenase genes Liu, C; Fetterman, JL; Liu, P et al. Hum. Genet., DOI://10.1007/s00439-018-1873-4 (2018)
A Latent Variable Approach to Differentiating Neural Mechanisms of Irritability and Anxiety in Youth Kircanski, K; White, LK; Tseng, WL et al. JAMA Psychiatry, DOI://10.1001/jamapsychiatry.2018.0468 (2018)
The impact of aging on primate hematopoiesis as interrogated by clonal tracking Yu, KR; Espinoza, DA; Wu, C et al. Blood, DOI://10.1182/blood-2017-08-802033 (2018)
Inferring properties of disordered chains from FRET transfer efficiencies Zheng, W; Zerze, GH; Borgia, A; Mittal, J; Schuler, B; Best, RB; J Chem Phys, DOI://10.1063/1.5006954 (2018)
A Novel Method to Extend a Partial-Body CT for the Reconstruction of Dose to Organs beyond the Scan Range Kuzmin, GA; Mille, MM; Jung, JW et al. Radiat. Res., DOI://10.1667/RR14999.1 (2018)

Association of Methylation Signals With Incident Coronary Heart Disease in an Epigenome-Wide Assessment of Circulating Tumor Necrosis Factor α Aslibekyan, S; Agha, G; Colicino, E et al. JAMA Cardiol, DOI://10.1001/jamacardio.2018.0510 (2018)
A method for determining haploid and triploid genotypes and their association with vascular phenotypes in Williams syndrome and 7q11.23 duplication syndrome Gregory, MD; Kolachana, B; Yao, Y et al. BMC Med. Genet., DOI://10.1186/s12881-018-0563-3 (2018)
IL1RN Variation Influences both Disease Susceptibility and Response to Human Recombinant IL-1RA Therapy in Systemic Juvenile Idiopathic Arthritis Arthur, VL; Shuldiner, E; Remmers, EF et al. , DOI://10.1002/art.40498 (2018)
Genome-wide Analyses Identify KIF5A as a Novel ALS Gene Nicolas, A; Kenna, KP; Renton, AE et al. Neuron, DOI://10.1016/j.neuron.2018.02.027 (2018)
Emollient use alters skin barrier and microbes in infants at risk for developing atopic dermatitis Glatz, M; Jo, JH; Kennedy, EA et al. PLoS ONE, DOI://10.1371/journal.pone.0192443 (2018)
Quantification of Human Microbiome Stability Over Six Months: Implications for Epidemiologic Studies Sinha, R; Goedert, JJ; Vogtmann, E et al. Am. J. Epidemiol., DOI://10.1093/aje/kwy064 (2018)

A trapped human PPM1A-phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity Debnath, S; Kosek, D; Tagad, HD et al. J. Biol. Chem., DOI://10.1074/jbc.RA117.001213 (2018)
Default Mode Connectivity in Major Depressive Disorder Measured Up to 10 Days After Ketamine Administration Evans, JW; Szczepanik, J; Brutsché, N; Park, LT; Nugent, AC; Zarate, CA; Biol. Psychiatry, DOI://10.1016/j.biopsych.2018.01.027 (2018)
An Extended Guinier Analysis for Intrinsically Disordered Proteins Zheng, W; Best, RB; J. Mol. Biol., DOI://10.1016/j.jmb.2018.03.007 (2018)
ZFR coordinates crosstalk between RNA decay and transcription in innate immunity Haque, N; Ouda, R; Chen, C; Ozato, K; Hogg, JR; Nat Commun, DOI://10.1038/s41467-018-03326-5 (2018)
Lifestyle, metabolite, and genetic determinants of formate concentrations in a cross-sectional study in young, healthy adults Brosnan, JT; Mills, JL; Ueland, PM et al. Am. J. Clin. Nutr., DOI://10.1093/ajcn/nqx065 (2018)
Shep regulates Drosophila neuronal remodeling by controlling transcription of its chromatin targets Chen, D; Dale, RK; Lei, EP; Development, DOI://10.1242/dev.154047 (2018)

Balancing Force Field Protein-Lipid Interactions To Capture Transmembrane Helix-Helix Association Domanski, J; Sansom, MSP; Stansfeld, PJ; Best, RB; J Chem Theory Comput, DOI://10.1021/acs.jctc.7b00983 (2018)
Metabolic profiles of triple-negative and luminal A breast cancer subtypes in African-American identify key metabolic differences Tayyari, F; Gowda, GAN; Olopade, OF et al. Oncotarget, DOI://10.18632/oncotarget.24433 (2018)
Targeting loss of the Hippo signaling pathway in NF2-deficient papillary kidney cancers Sourbier, C; Liao, PJ; Ricketts, CJ et al. Oncotarget, DOI://10.18632/oncotarget.24112 (2018)
Gestational cytokine concentrations and neurocognitive development at 7 years Ghassabian, A; Albert, PS; Hornig, M et al. Transl Psychiatry, DOI://10.1038/s41398-018-0112-z (2018)
LMTK3 confers chemo-resistance in breast cancer Stebbing, J; Shah, K; Lit, LC et al. Oncogene, DOI://10.1038/s41388-018-0197-0 (2018)
Argonaute2 and LaminB modulate gene expression by controlling chromatin topology Nazer, E; Dale, RK; Chinen, M; Radmanesh, B; Lei, EP; PLoS Genet., DOI://10.1371/journal.pgen.1007276 (2018)

A deep insight into the male and female sialotranscriptome of adult Culex tarsalis mosquitoes Ribeiro, JMC; Martin-Martin, I; Moreira, FR; Bernard, KA; Calvo, E; Insect Biochem. Mol. Biol., DOI://10.1016/j.ibmb.2018.03.001 (2018)
In Vitro Modeling of Human Germ Cell Development Using Pluripotent Stem Cells Zhao, Y; Ye, S; Liang, D et al. Stem Cell Reports, DOI://10.1016/j.stemcr.2018.01.001 (2018)
Evidence of subgroups in smokers as revealed in clinical measures and evaluated by neuroimaging data: a preliminary study Ding, X; Salmeron, BJ; Wang, J; Yang, Y; Stein, EA; Ross, TJ; Addict Biol, DOI://10.1111/adb.12620 (2018)
Co-evolutionary fitness landscapes for sequence design Tian, P; Louis, JM; Baber, JL; Aniana, A; Best, R; Angew. Chem. Int. Ed. Engl., DOI://10.1002/anie.201713220 (2018)
An Efficient Single-Cell RNA-Seq Approach to Identify Neoantigen-Specific T Cell Receptors Lu, YC; Zheng, Z; Robbins, PF et al. Mol. Ther., DOI://10.1016/j.ymthe.2017.10.018 (2018)
Mechanism of Darunavir (DRV)'s High Genetic Barrier to HIV-1 Resistance: A Key V32I Substitution in Protease Rarely Occurs, but Once It Occurs, It Predisposes HIV-1 To Develop DRV Resistance Aoki, M; Das, D; Hayashi, H et al. MBio, DOI://10.1128/mBio.02425-17 (2018)

Nanopore sequencing and assembly of a human genome with ultra-long reads Jain, M; Koren, S; Miga, KH et al. Nat. Biotechnol., DOI://10.1038/nbt.4060 (2018)
Impact of time-of-day on diffusivity measures of brain tissue derived from diffusion tensor imaging Thomas, C; Sadeghi, N; Nayak, A et al. Neuroimage, DOI://10.1016/j.neuroimage.2018.02.026 (2018)
Verdazyl-ribose: A new radical for solid-state dynamic nuclear polarization at high magnetic field Thurber, KR; Le, TN; Changcoco, V; Brook, DJR; J. Magn. Reson., DOI://10.1016/j.jmr.2018.02.016 (2018)
Minoxidil improves vascular compliance, restores cerebral blood flow and alters extracellular matrix gene expression in a model of chronic vascular stiffness Knutsen, R; Beeman, SC; Broekelmann, TJ et al. Am. J. Physiol. Heart Circ. Physiol., DOI://10.1152/ajpheart.00683.2017 (2018)
An insight into the salivary gland and fat body transcriptome of Panstrongylus lignarius (Hemiptera: Heteroptera), the main vector of Chagas disease in Peru Nevoa, JC; Mendes, MT; da Silva, MV; Soares, SC; Oliveira, CJF; Ribeiro, JMC; PLoS Negl Trop Dis, DOI://10.1371/journal.pntd.0006243 (2018)
Ketamine has distinct electrophysiological and behavioral effects in depressed and healthy subjects Nugent, AC; Ballard, ED; Gould, TD et al. Mol. Psychiatry, DOI://10.1038/s41380-018-0028-2 (2018)

Highly Disordered Amyloid-β Monomer Probed by Single-Molecule FRET and MD Simulation Meng, F; Bellaiche, MMJ; Kim, JY; Zerze, GH; Best, RB; Chung, HS; Biophys. J., DOI://10.1016/j.bpj.2017.12.025 (2018)
Identification of Casz1 as a Regulatory Protein Controlling T Helper Cell Differentiation, Inflammation, and Immunity Bhaskaran, N; Liu, Z; Saravanamuthu, SS et al. Front Immunol, DOI://10.3389/fimmu.2018.00184 (2018)
GRL-079, a Novel HIV-1 Protease Inhibitor, Is Extremely Potent against Multidrug-Resistant HIV-1 Variants and Has a High Genetic Barrier against the Emergence of Resistant Variants Delino NS, Aoki M, Hayashi H, Hattori SI, Chang SB, Takamatsu Y, Martyr CD, Das D, Ghosh AK, Mitsuya H Antimicrob Agents Chemother. , doi: 10.1128/AAC.02060-17 (2018)
Design and statistical considerations for studies evaluating the efficacy of a single dose of the human papillomavirus (HPV) vaccine Sampson, JN; Hildesheim, A; Herrero, R; Gonzalez, P; Kreimer, A; Gail, MH; Contemp Clin Trials, DOI://10.1016/j.cct.2018.02.010 (2018)
Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas Cobo, I; Martinelli, P; Flández, M et al. Nature, DOI://10.1038/nature25751 (2018)
Estimating recurrence and incidence of preterm birth subject to measurement error in gestational age: A hidden Markov modeling approach Albert, PS Stat Med, DOI://10.1002/sim.7624 (2018)

Extreme disorder in an ultrahigh-affinity protein complex Borgia, A; Borgia, MB; Bugge, K et al. Nature, DOI://10.1038/nature25762 (2018)
Epigenome comparisons reveal linkage between gene expression and postnatal remodeling of chromatin domain topology Howard, BH; Hirai, TH; Russanova, VR; PLoS ONE, DOI://10.1371/journal.pone.0191033 (2018)
Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells Hu, G; Cui, K; Fang, D et al. Immunity, DOI://10.1016/j.immuni.2018.01.013 (2018)
Structural Modulation of Human Amylin Protofilaments by Naturally Occurring Mutations Tofoleanu, F; Yuan, Y; Pickard, FC; Tywoniuk, B; Brooks, BR; Buchete, NV; J Phys Chem B, DOI://10.1021/acs.jpcb.7b12083 (2018)
Assessment of PCXMC for patients with different body size in chest and abdominal x ray examinations: a Monte Carlo simulation study Borrego, D; Lowe, EM; Kitahara, CM; Lee, C; Phys Med Biol, DOI://10.1088/1361-6560/aab13e (2018)
Dose coefficients for children and young adolescents exposed to external neutron fields Griffin, KT; Mille, M; Lee, C; J Radiol Prot, DOI://10.1088/1361-6498/aab126 (2018)

CD63, MHC class 1, and CD47 identify subsets of extracellular vesicles containing distinct populations of noncoding RNAs Kaur, S; Elkahloun, AG; Arakelyan, A et al. Sci Rep, DOI://10.1038/s41598-018-20936-7 (2018)
Transient Receptor Potential Channels TRPM4 and TRPC3 Critically Contribute to Respiratory Motor Pattern Formation but not Rhythmogenesis in Rodent Brainstem Circuits Koizumi, H; John, TT; Chia, JX et al. eNeuro, DOI://10.1523/ENEURO.0332-17.2018 (2018)
Ridding fMRI data of motion-related influences: Removal of signals with distinct spatial and physical bases in multiecho data Power, JD; Plitt, M; Gotts, SJ et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1720985115 (2018)
The Antimicrobial Peptide CRAMP Is Essential for Colon Homeostasis by Maintaining Microbiota Balance Yoshimura, T; McLean, MH; Dzutsev, AK et al. J. Immunol., DOI://10.4049/jimmunol.1602073 (2018)
Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of Bacterial Plasmids Conferring Carbapenem Resistance Weingarten, RA; Johnson, RC; Conlan, S et al. MBio, DOI://10.1128/mBio.02011-17 (2018)
5-Azacytidine prevents relapse and produces long-term complete remissions in leukemia xenografts treated with Moxetumomab pasudotox Müller, F; Cunningham, T; Stookey, S et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1714512115 (2018)

Raf-1 Cysteine-Rich Domain Increases the Affinity of K-Ras/Raf at the Membrane, Promoting MAPK Signaling Li, S; Jang, H; Zhang, J; Nussinov, R; Structure, DOI://10.1016/j.str.2018.01.011 (2018)
Global changes of H3K27me3 domains and Polycomb group protein distribution in the absence of recruiters Spps or Pho Brown, JL; Sun, MA; Kassis, JA; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1716299115 (2018)
Precise genome-wide mapping of single nucleosomes and linkers in vivo Chereji, RV; Ramachandran, S; Bryson, TD; Henikoff, S; Genome Biol., DOI://10.1186/s13059-018-1398-0 (2018)
Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer Klein, AP; Wolpin, BM; Risch, HA et al. Nat Commun, DOI://10.1038/s41467-018-02942-5 (2018)
The klotho-related protein KLPH (lctl) has preferred expression in lens and is essential for expression of clic5 and normal lens suture formation Fan, J; Lerner, J; Wyatt, MK et al. Exp. Eye Res., DOI://10.1016/j.exer.2018.02.001 (2018)
Self-reported executive function and hoarding in adults with obsessive-compulsive disorder Samuels, J; Bienvenu, OJ; Krasnow, J et al. Compr Psychiatry, DOI://10.1016/j.comppsych.2017.11.009 (2018)

Sequence determinants of protein phase behavior from a coarse-grained model Dignon, GL; Zheng, W; Kim, YC; Best, RB; Mittal, J; PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1005941 (2018)
Genomic Heterogeneity Within Individual Prostate Cancer Foci Impacts Predictive Biomarkers of Targeted Therapy VanderWeele, DJ; Finney, R; Katayama, K et al. Eur Urol Focus, DOI://10.1016/j.euf.2018.01.006 (2018)
Extended amygdala connectivity changes during sustained shock anticipation Torrisi, S; Gorka, AX; Gonzalez-Castillo, J et al. Transl Psychiatry, DOI://10.1038/s41398-017-0074-6 (2018)
Unraveling the molecular mechanism of interactions of the Rho GTPases Cdc42 and Rac1 with the scaffolding protein IQGAP2 Ozdemir, ES; Jang, H; Gursoy, A et al. J. Biol. Chem., DOI://10.1074/jbc.RA117.001596 (2018)
Binding kinetics of ultrasmall gold nanoparticles with proteins André Lira, Rodrigo Ferreira, Ricardo Torquato, Huaying Zhao, Maria Luiza Oliva, Sergio A. Hassan, Peter Schuck and Alioscka A Sousa Nanoscale, DOI: 10.1039/C7NR06810G (2018)
Cleavage of TL1A Differentially Regulates Its Effects on Innate and Adaptive Immune Cells Ferdinand, JR; Richard, AC; Meylan, F; Al-Shamkhani, A; Siegel, RM; J. Immunol., DOI://10.4049/jimmunol.1700891 (2018)

De novo assembly of the complex genome of Nippostrongylus brasiliensis using MinION long reads Eccles, D; Chandler, J; Camberis, M et al. BMC Biol., DOI://10.1186/s12915-017-0473-4 (2018)
Accelerometer-Measured Physical Activity and Sedentary Behavior in Relation to All-Cause Mortality: The Women's Health Study Lee, IM; Shiroma, EJ; Evenson, KR; Kamada, M; LaCroix, AZ; Buring, JE; Circulation, DOI://10.1161/CIRCULATIONAHA.117.031300 (2018)
Altered avalanche dynamics in a developmental NMDAR hypofunction model of cognitive impairment Seshadri, S; Klaus, A; Winkowski, DE; Kanold, PO; Plenz, D; Transl Psychiatry, DOI://10.1038/s41398-017-0060-z (2018)
Single-cell analysis reveals cancer stem cell heterogeneity in hepatocellular carcinoma Zheng, H; Pomyen, Y; Hernandez, MO et al. Hepatology, DOI://10.1002/hep.29778 (2018)
Prediction of nearest neighbor effects on backbone torsion angles and NMR scalar coupling constants in disordered proteins Shen, Y; Roche, J; Grishaev, A; Bax, A; Protein Sci., DOI://10.1002/pro.3292 (2018)

2017 (396 papers)

SpotLearn: Convolutional Neural Network for Detection of Fluorescence In Situ Hybridization (FISH) Signals in High-Throughput Imaging Approaches Gudla, PR; Nakayama, K; Pegoraro, G; Misteli, T; Cold Spring Harb. Symp. Quant. Biol., DOI://10.1101/sqb.2017.82.033761 (2017)

Effects of spatial fMRI resolution on the classification of naturalistic movies Mandelkow, H; de Zwart, JA; Duyn, JH; Neuroimage, DOI://10.1016/j.neuroimage.2017.08.053 (2017)
Extracellular vesicles, exosomes and shedding vesicles in regenerative medicine - a new paradigm for tissue repair Bjørge, IM; Kim, SY; Mano, JF; Kalionis, B; Chrzanowski, W; Biomater Sci, DOI://10.1039/c7bm00479f (2017)
Automatic magnetic resonance prostate segmentation by deep learning with holistically nested networks Cheng, R; Roth, HR; Lay, N et al. J Med Imaging (Bellingham), DOI://10.1117/1.JMI.4.4.041302 (2017)
The emerging importance and challenges of the human mycobiome Kong, HH; Morris, A; Virulence, DOI://10.1080/21505594.2017.1279780 (2017)
Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells Lin, JX; Du, N; Li, P et al. Nat Commun, DOI://10.1038/s41467-017-01477-5 (2017)
BRD4 facilitates DNA damage response and represses CBX5/Heterochromatin protein 1 (HP1) Pongas, G; Kim, MK; Min, DJ et al. Oncotarget, DOI://10.18632/oncotarget.17572 (2017)

Bitopic fluorescent antagonists of the A2A adenosine receptor based on pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine functionalized congeners Duroux, R; Ciancetta, A; Mannes, P et al. Medchemcomm, DOI://10.1039/C7MD00247E (2017)
Haploinsufficiency of ZNF462 is associated with craniofacial anomalies, corpus callosum dysgenesis, ptosis, and developmental delay Weiss, K; Wigby, K; Fannemel, M et al. Eur. J. Hum. Genet., DOI://10.1038/ejhg.2017.86 (2017)
Longitudinal Structural and Functional Differences Between Proportional and Poor Motor Recovery After Stroke Guggisberg, AG; Nicolo, P; Cohen, LG; Schnider, A; Buch, ER; Neurorehabil Neural Repair, DOI://10.1177/1545968317740634 (2017)
STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes: Functional dissection of the Il2ra gene locus Li, P; Mitra, S; Spolski, R et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1714019114 (2017)
Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis van Rooij, FJA; Qayyum, R; Smith, AV et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2016.11.016 (2017)
Testis-specific transcriptional regulators selectively occupy BORIS-bound CTCF target regions in mouse male germ cells Rivero-Hinojosa, S; Kang, S; Lobanenkov, VV; Zentner, GE; Sci Rep, DOI://10.1038/srep41279 (2017)

Common Molecular Subtypes Among Asian Hepatocellular Carcinoma and Cholangiocarcinoma Chaisaingmongkol, J; Budhu, A; Dang, H et al. Cancer Cell, DOI://10.1016/j.ccell.2017.05.009 (2017)
Visualizing abnormalities in chest radiographs through salient network activations in Deep Learning Rajaraman S, Antani SK, Xue Z, Candemir S, Jaeger S, Thoma GR Proc. IEEE Life Sciences Conference (LSC), Sydney, Australia, 10.1109/LSC.2017.826814 (2017)
PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability Gryder, BE; Yohe, ME; Chou, HC et al. Cancer Discov, DOI://10.1158/2159-8290.CD-16-1297 (2017)
Parental bonding and hoarding in obsessive-compulsive disorder Chen, D; Bienvenu, OJ; Krasnow, J et al. Compr Psychiatry, DOI://10.1016/j.comppsych.2016.11.004 (2017)
Characterization of an Immunogenic Mutation in a Patient with Metastatic Triple-Negative Breast Cancer Assadipour, Y; Zacharakis, N; Crystal, JS et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-16-1423 (2017)
Systems-level identification of PKA-dependent signaling in epithelial cells Isobe, K; Jung, HJ; Yang, CR et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1709123114 (2017)
Association of red cell distribution width with all-cause and cardiovascular-specific mortality in African American and white adults: a prospective cohort study Tajuddin, SM; Nalls, MA; Zonderman, AB; Evans, MK; J Transl Med, DOI://10.1186/s12967-017-1313-6 (2017)
Sieve analysis using the number of infecting pathogens Follmann, D; Huang, CY; Biometrics, DOI://10.1111/biom.12833 (2017)
Meat Consumption During Pregnancy and Substance Misuse Among Adolescent Offspring: Stratification of TCN2 Genetic Variants Hibbeln, JR; SanGiovanni, JP; Golding, J et al. Alcohol. Clin. Exp. Res., DOI://10.1111/acer.13494 (2017)
A Systems Biology Approach to Investigating Sex Differences in Cardiac Hypertrophy Harrington, J; Fillmore, N; Gao, S et al. J Am Heart Assoc, DOI://10.1161/JAHA.117.005838 (2017)
Applying rigor and reproducibility standards to assay donor-derived cell-free DNA as a non-invasive method for detection of acute rejection and graft injury after heart transplantation Agbor-Enoh, S; Tunc, I; De Vlaminck, I et al. J. Heart Lung Transplant., DOI://10.1016/j.healun.2017.05.026 (2017)
Broadly protective murine monoclonal antibodies against influenza B virus target highly conserved neuraminidase epitopes Wohlbold, TJ; Podolsky, KA; Chromikova, V et al. Nat Microbiol, DOI://10.1038/s41564-017-0011-8 (2017)

Genome-wide association meta-analysis of fish and EPA+DHA consumption in 17 US and European cohorts Mozaffarian, D; Dashti, HS; Wojczynski, MK et al. PLoS ONE, DOI://10.1371/journal.pone.0186456 (2017)
Amygdala Contributions to Stimulus-Reward Encoding in the Macaque Medial and Orbital Frontal Cortex during Learning Rudebeck, PH; Ripple, JA; Mitz, AR; Averbeck, BB; Murray, EA; J. Neurosci., DOI://10.1523/JNEUROSCI.0933-16.2017 (2017)
Genome-wide identification of histone H2A and histone variant H2A.Z-interacting proteins by bPPI-seq Zhang, Y; Ku, WL; Liu, S et al. Cell Res., DOI://10.1038/cr.2017.112 (2017)
Deciphering the olfactory repertoire of the tiger mosquito Aedes albopictus Lombardo, F; Salvemini, M; Fiorillo, C et al. BMC Genomics, DOI://10.1186/s12864-017-4144-1 (2017)
Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS Taskesen, E; Mishra, A; van der Sluis, S et al. Sci Rep, DOI://10.1038/s41598-017-09320-z (2017)
Shelterin components mediate genome reorganization in response to replication stress Mizuguchi, T; Taneja, N; Matsuda, E et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1705527114 (2017)

The Interplay between Long- and Short-Range Temporal Correlations Shapes Cortex Dynamics across Vigilance States Meisel, C; Klaus, A; Vyazovskiy, VV; Plenz, D; J. Neurosci., DOI://10.1523/JNEUROSCI.0448-17.2017 (2017)
Insights Into Onchocerca volvulus Population Biology Through Multilocus Immunophenotyping Norice-Tra, CT; Ribeiro, J; Bennuru, S et al. J. Infect. Dis., DOI://10.1093/infdis/jix394 (2017)
Dynamic landscape of alternative polyadenylation during retinal development Hu, W; Li, S; Park, JY et al. Cell. Mol. Life Sci., DOI://10.1007/s00018-016-2429-1 (2017)
An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype Direk, N; Williams, S; Smith, JA et al. Biol. Psychiatry, DOI://10.1016/j.biopsych.2016.11.013 (2017)
The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins Wang, AH; Juan, AH; Ko, KD et al. Mol. Cell, DOI://10.1016/j.molcel.2017.09.016 (2017)
Untimely expression of gametogenic genes in vegetative cells causes uniparental disomy Folco, HD; Chalamcharla, VR; Sugiyama, T et al. Nature, DOI://10.1038/nature21372 (2017)
Pyrimidine Nucleotides Containing a (S)-Methanocarba Ring as P2Y6 Receptor Agonists Toti, KS; Jain, S; Ciancetta, A et al. Medchemcomm, DOI://10.1039/C7MD00397H (2017)
NFκB Promotes Ovarian Tumorigenesis via Classical Pathways That Support Proliferative Cancer Cells and Alternative Pathways That Support ALDH+ Cancer Stem-like Cells House, CD; Jordan, E; Hernandez, L et al. Cancer Res., DOI://10.1158/0008-5472.CAN-17-0366 (2017)
ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer Shukla, V; Rao, M; Zhang, H et al. Cancer Res., DOI://10.1158/0008-5472.CAN-17-0570 (2017)
SNF2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance and Proper Replication Taneja, N; Zofall, M; Balachandran, V et al. Mol. Cell, DOI://10.1016/j.molcel.2017.02.006 (2017)
High-Resolution CBV-fMRI Allows Mapping of Laminar Activity and Connectivity of Cortical Input and Output in Human M1 Huber, L; Handwerker, DA; Jangraw, DC et al. Neuron, DOI://10.1016/j.neuron.2017.11.005 (2017)
KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis Murgai, M; Ju, W; Eason, M et al. Nat. Med., DOI://10.1038/nm.4400 (2017)

CTCF-Mediated Enhancer-Promoter Interaction Is a Critical Regulator of Cell-to-Cell Variation of Gene Expression Ren, G; Jin, W; Cui, K et al. Mol. Cell, DOI://10.1016/j.molcel.2017.08.026 (2017)
Bromodomain and Extraterminal Protein Inhibitor JQ1 Suppresses Thyroid Tumor Growth in a Mouse Model Zhu, X; Enomoto, K; Zhao, L et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-16-0914 (2017)
Molecular-based diagnosis of multiple sclerosis and its progressive stage Barbour, C; Kosa, P; Komori, M et al. Ann. Neurol., DOI://10.1002/ana.25083 (2017)
Serum starvation of ARPE-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration Rajapakse, D; Peterson, K; Mishra, S; Wistow, G; Exp. Cell Res., DOI://10.1016/j.yexcr.2017.10.036 (2017)
Crystal Structures of Diaryliodonium Fluorides and Their Implications for Fluorination Mechanisms Lee, YS; Chun, JH; Hodošček, M; Pike, VW; Chemistry, DOI://10.1002/chem.201604803 (2017)
Loci associated with skin pigmentation identified in African populations Crawford, NG; Kelly, DE; Hansen, MEB et al. Science, DOI://10.1126/science.aan8433 (2017)

eIF1A residues implicated in cancer stabilize translation preinitiation complexes and favor suboptimal initiation sites in yeast Martin-Marcos, P; Zhou, F; Karunasiri, C et al. Elife, DOI://10.7554/eLife.31250 (2017)
Polygenic risk score and heritability estimates reveals a genetic relationship between ASD and OCD Guo, W; Samuels, JF; Wang, Y et al. Eur Neuropsychopharmacol, DOI://10.1016/j.euroneuro.2017.03.011 (2017)
Molecular basis of CENP-C association with the CENP-A nucleosome at yeast centromeres Xiao, H; Wang, F; Wisniewski, J et al. Genes Dev., DOI://10.1101/gad.304782.117 (2017)
T-Cell Transfer Therapy Targeting Mutant KRAS Rosenberg, SA; Tran, E; Robbins, PF; N. Engl. J. Med., DOI://10.1056/NEJMc1616637 (2017)
Correction: The complex genetics of gait speed: genome-wide meta-analysis approach Ben-Avraham, D; Karasik, D; Verghese, J et al. Aging (Albany NY), DOI://10.18632/aging.101260 (2017)
Effect of Threat on Right dlPFC Activity during Behavioral Pattern Separation Balderston, NL; Hsiung, A; Ernst, M; Grillon, C; J. Neurosci., DOI://10.1523/JNEUROSCI.0717-17.2017 (2017)

GATE: an efficient procedure in study of pleiotropic genetic associations Zhang, W; Yang, L; Tang, LL et al. BMC Genomics, DOI://10.1186/s12864-017-3928-7 (2017)
Progressive and Multi-path Holistically Nested Neural Networks for Pathological Lung Segmentation from CT Images Harrison A.P., Xu Z., George K., Lu L., Summers R.M., Mollura D.J. In: Descoteaux M., Maier-Hein L., Franz A., Jannin P., Colli, 10.1007/978-3-319-66179-7-71 (2017)
Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease Warren, CR; O'Sullivan, JF; Friesen, M et al. Cell Stem Cell, DOI://10.1016/j.stem.2017.01.010 (2017)
An Adult Mouse Thyroid Side Population Cell Line that Exhibits Enriched Epithelial-Mesenchymal Transition Murata, T; Iwadate, M; Takizawa, Y et al. Thyroid, DOI://10.1089/thy.2016.0130 (2017)
NRF1 coordinates with DNA methylation to regulate spermatogenesis Wang, J; Tang, C; Wang, Q et al. FASEB J., DOI://10.1096/fj.201700093R (2017)
Two Distinct Actin Networks Mediate Traction Oscillations to Confer Focal Adhesion Mechanosensing Wu, Z; Plotnikov, SV; Moalim, AY; Waterman, CM; Liu, J; Biophys. J., DOI://10.1016/j.bpj.2016.12.035 (2017)
'Final common pathway' of human cancer immunotherapy: targeting random somatic mutations Tran, E; Robbins, PF; Rosenberg, SA; Nat. Immunol., DOI://10.1038/ni.3682 (2017)
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 Expression Parkhurst, M; Gros, A; Pasetto, A et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-16-2680 (2017)
The Distinct Transcriptional Response of the Midgut of Amblyomma sculptum and Amblyomma aureolatum Ticks to Rickettsia rickettsii Correlates to Their Differences in Susceptibility to Infection Martins, LA; Galletti, MFBM; Ribeiro, JM et al. Front Cell Infect Microbiol, DOI://10.3389/fcimb.2017.00129 (2017)
Defining Disease, Diagnosis, and Translational Medicine within a Homeostatic Perturbation Paradigm: The National Institutes of Health Undiagnosed Diseases Program Experience Gall, T; Valkanas, E; Bello, C et al. Front Med (Lausanne), DOI://10.3389/fmed.2017.00062 (2017)
Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations Hu, Y; Tanaka, T; Zhu, J et al. J. Lipid Res., DOI://10.1194/jlr.P071860 (2017)
Binding of protofibrillar Aβ trimers to lipid bilayer surface enhances Aβ structural stability and causes membrane thinning Dong, X; Sun, Y; Wei, G; Nussinov, R; Ma, B; Phys Chem Chem Phys, DOI://10.1039/c7cp05959k (2017)

Temporal similarity perfusion mapping: A standardized and model-free method for detecting perfusion deficits in stroke Song, S; Bokkers, RPH; Luby, M et al. PLoS ONE, DOI://10.1371/journal.pone.0185552 (2017)
Genome Wide Association Study (GWAS) between Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD) Ritter, ML; Guo, W; Samuels, JF et al. Front Mol Neurosci, DOI://10.3389/fnmol.2017.00083 (2017)
Extending electrostatics of dielectric spheres to arbitrary charge distributions with applications to biosystems T. P. Doerr, O. I. Obolensky, and Yi-Kuo Yu Phys. Rev. E , doi://10.1103/PhysRevE.96.062414 (2017)
The full transcription map of mouse papillomavirus type 1 (MmuPV1) in mouse wart tissues Xue, XY; Majerciak, V; Uberoi, A et al. PLoS Pathog., DOI://10.1371/journal.ppat.1006715 (2017)
Reduced Local and Increased Long-Range Functional Connectivity of the Thalamus in Autism Spectrum Disorder Tomasi, D; Volkow, ND; Cereb. Cortex, DOI://10.1093/cercor/bhx340 (2017)
Highly Efficient Cpf1-Mediated Gene Targeting in Mice Following High Concentration Pronuclear Injection Watkins-Chow, DE; Varshney, GK; Garrett, LJ et al. G3 (Bethesda), DOI://10.1534/g3.116.038091 (2017)

CDC14A Phosphatase is Essential for Hearing and Male Fertility in Mouse and Human Imtiaz, A; Belyantseva, IA; Beirl, AJ et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddx440 (2017)
Identifying subgroups of enhanced predictive accuracy from longitudinal biomarker data using tree-based approaches: applications to fetal growth Foster, JC; Liu, D; Albert, PS; Liu, A; J R Stat Soc Ser A Stat Soc, DOI://10.1111/rssa.12182 (2017)
Effects of HLA-B27 on Gut Microbiota in Experimental Spondyloarthritis Implicate an Ecological Model of Dysbiosis Gill, T; Asquith, M; Brooks, SR; Rosenbaum, JT; Colbert, RA; Arthritis Rheumatol., DOI://10.1002/art.40405 (2017)
Generation and characterization of Kctd15 mutations in zebrafish Heffer, A; Marquart, GD; Aquilina-Beck, A; Saleem, N; Burgess, HA; Dawid, IB; PLoS ONE, DOI://10.1371/journal.pone.0189162 (2017)
Selection for long and short sleep duration in Drosophila melanogaster reveals the complex genetic network underlying natural variation in sleep Harbison, ST; Serrano Negron, YL; Hansen, NF; Lobell, AS; PLoS Genet., DOI://10.1371/journal.pgen.1007098 (2017)
Structural mechanisms of centromeric nucleosome recognition by the kinetochore protein CENP-N Chittori, S; Hong, J; Saunders, H et al. Science, DOI://10.1126/science.aar2781 (2017)

Identity-by-Descent Mapping Identifies Major Locus for Serum Triglycerides in Amerindians Largely Explained by an APOC3 Founder Mutation Hsueh, WC; Nair, AK; Kobes, S et al. Circ Cardiovasc Genet, DOI://10.1161/CIRCGENETICS.117.001809 (2017)
Detecting treatment differences in group sequential longitudinal studies with covariate adjustment Jeffries, NO; Troendle, JF; Geller, NL; Biometrics, DOI://10.1111/biom.12837 (2017)
Comparison of Additive and Polarizable Models with Explicit Treatment of Long-Range Lennard-Jones Interactions using Alkane Simulations Leonard, AN; Simmonett, AC; Pickard, FC et al. J Chem Theory Comput, DOI://10.1021/acs.jctc.7b00948 (2017)
Structural basis for nucleotide-modulated p97 association with the ER membrane Tang, WK; Zhang, T; Ye, Y; Xia, D; Cell Discov, DOI://10.1038/celldisc.2017.45 (2017)
Structural host-microbiota interaction networks Guven-Maiorov, E; Tsai, CJ; Nussinov, R; PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1005579 (2017)
Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq Chen, L; Lee, JW; Chou, CL et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1710964114 (2017)

Exploring Effects of Sex and Diet on Drosophila melanogaster Head Gene Expression Jaime, MDLA; Hurtado, J; Loustalot-Laclette, MR; Oliver, B; Markow, T; J Genomics, DOI://10.7150/jgen.22393 (2017)
The emergence and evolution of influenza A (H1α) viruses in swine in Canada and the United States Nelson, MI; Culhane, MR; Trovão, NS et al. J. Gen. Virol., DOI://10.1099/jgv.0.000924 (2017)
New Multiple Sclerosis Disease Severity Scale Predicts Future Accumulation of Disability Weideman, AM; Barbour, C; Tapia-Maltos, MA et al. Front Neurol, DOI://10.3389/fneur.2017.00598 (2017)
CRISPR/Cas9-mediated gene knockout is insensitive to target copy number but is dependent on guide RNA potency and Cas9/sgRNA threshold expression level Yuen, G; Khan, FJ; Gao, S et al. Nucleic Acids Res., DOI://10.1093/nar/gkx843 (2017)
Graph theory reveals amygdala modules consistent with its anatomical subdivisions Caparelli, EC; Ross, TJ; Gu, H; Liang, X; Stein, EA; Yang, Y; Sci Rep, DOI://10.1038/s41598-017-14613-4 (2017)
Molecular Anatomy of the Developing Human Retina Hoshino, A; Ratnapriya, R; Brooks, MJ et al. Dev. Cell, DOI://10.1016/j.devcel.2017.10.029 (2017)
Arginine Kinases from the Precious Corals Corallium rubrum and Paracorallium japonicum: Presence of Two Distinct Arginine Kinase Gene Lineages in Cnidarians Matsuo, T; Yano, D; Uda, K; Iwasaki, N; Suzuki, T; Protein J., DOI://10.1007/s10930-017-9745-7 (2017)
Lasting deficit in inhibitory control with mild traumatic brain injury Xu, B; Sandrini, M; Levy, S et al. Sci Rep, DOI://10.1038/s41598-017-14867-y (2017)
Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions Kim, J; Sturgill, D; Sebastian, R et al. Mol. Cell, DOI://10.1016/j.molcel.2017.11.021 (2017)
Dosage-Dependent Expression Variation Suppressed on the Drosophila Male X Chromosome Lee, H; Cho, DY; Wojtowicz, D et al. G3 (Bethesda), DOI://10.1534/g3.117.300400 (2017)
Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance Rosshart, SP; Vassallo, BG; Angeletti, D et al. Cell, DOI://10.1016/j.cell.2017.09.016 (2017)
Dynamic regulation of lysine acetylation: the balance between acetyltransferase and deacetylase activities Hyndman, KA; Knepper, MA; Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00313.2017 (2017)

Integrative Genomic Analysis of Coincident Cancer Foci Implicates CTNNB1 and PTEN Alterations in Ductal Prostate Cancer Gillard, M; Lack, J; Pontier, A et al. Eur Urol Focus, DOI://10.1016/j.euf.2017.12.003 (2017)
Holistic segmentation of the lung in cine MRI Kovacs, W; Hsieh, N; Roth, H et al. J Med Imaging (Bellingham), DOI://10.1117/1.JMI.4.4.041310 (2017)
Identification of essential genes for cancer immunotherapy Patel, SJ; Sanjana, NE; Kishton, RJ et al. Nature, DOI://10.1038/nature23477 (2017)
Transcriptomic profiling of the human brain reveals that altered synaptic gene expression is associated with chronological aging Dillman, AA; Majounie, E; Ding, J et al. Sci Rep, DOI://10.1038/s41598-017-17322-0 (2017)
In vivo tropism of Salmonella Typhi toxin to cells expressing a multiantennal glycan receptor Yang, YA; Lee, S; Zhao, J et al. Nat Microbiol, DOI://10.1038/s41564-017-0076-4 (2017)
Local and global anatomy of antibody-protein antigen recognition Wang, M; Zhu, D; Zhu, J; Nussinov, R; Ma, B; J. Mol. Recognit., DOI://10.1002/jmr.2693 (2017)

A digital 3D atlas of the marmoset brain based on multi-modal MRI Liu, C; Ye, FQ; Chern-Chyi Yen, C et al. Neuroimage, DOI://10.1016/j.neuroimage.2017.12.004 (2017)
Automated quality assessment of structural magnetic resonance images in children: Comparison with visual inspection and surface-based reconstruction White, T; Jansen, PR; Muetzel, RL et al. Hum Brain Mapp, DOI://10.1002/hbm.23911 (2017)
Power Analysis for Genetic Association Test (PAGEANT) provides insights to challenges for rare variant association studies Derkach, A; Zhang, H; Chatterjee, N; Bioinformatics, DOI://10.1093/bioinformatics/btx770 (2017)
OCT4 supports extended LIF-independent self-renewal and maintenance of transcriptional and epigenetic networks in embryonic stem cells He, R; Xhabija, B; Al-Qanber, B; Kidder, BL; Sci Rep, DOI://10.1038/s41598-017-16611-y (2017)
Demystifying P2Y1 Receptor Ligand Recognition through Docking and Molecular Dynamics Analyses Ciancetta, A; O'Connor, RD; Paoletta, S; Jacobson, KA; J Chem Inf Model, DOI://10.1021/acs.jcim.7b00528 (2017)
Landscape of immunogenic tumor antigens in successful immunotherapy of virally induced epithelial cancer Stevanović, S; Pasetto, A; Helman, SR et al. Science, DOI://10.1126/science.aak9510 (2017)

HiHiMap: single-cell quantitation of histones and histone posttranslational modifications across the cell cycle by high-throughput imaging Zane, L; Chapus, F; Pegoraro, G; Misteli, T; Mol. Biol. Cell, DOI://10.1091/mbc.E16-12-0870 (2017)
A STAT3-dependent transcriptional circuitry inhibits cytotoxic gene expression in T cells Ciucci, T; Vacchio, MS; Bosselut, R; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1711160114 (2017)
Natural Language Processing for Large-Scale Medical Image Analysis Using Deep Learning Hoo-Chang Shin, Le Lu, Ronald M. Summers in Deep Learning for Medical Image Analysis, Elsevier , (p405-421) (2017)
Allometric Analysis Detects Brain Size-Independent Effects of Sex and Sex Chromosome Complement on Human Cerebellar Organization Mankiw, C; Park, MTM; Reardon, PK et al. J. Neurosci., DOI://10.1523/JNEUROSCI.2158-16.2017 (2017)
Excessive burden of lysosomal storage disorder gene variants in Parkinson's disease Robak, LA; Jansen, IE; van Rooij, J et al. Brain, DOI://10.1093/brain/awx285 (2017)
Insights into functions of the H channel of cytochrome c oxidase from atomistic molecular dynamics simulations Sharma, V; Jambrina, PG; Kaukonen, M; Rosta, E; Rich, PR; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1708628114 (2017)

Conventional and pioneer modes of glucocorticoid receptor interaction with enhancer chromatin in vivo Johnson, TA; Chereji, RV; Stavreva, DA; Morris, SA; Hager, GL; Clark, DJ; Nucleic Acids Res., DOI://10.1093/nar/gkx1044 (2017)
A joint model for multivariate hierarchical semicontinuous data with replications Kassahun-Yimer, W; Albert, PS; Lipsky, LM; Nansel, TR; Liu, A; Stat Methods Med Res, DOI://10.1177/0962280217738141 (2017)
Phosphorylated Calmodulin Promotes PI3K Activation by Binding to the SH2 Domains Zhang, M; Jang, H; Gaponenko, V; Nussinov, R; Biophys. J., DOI://10.1016/j.bpj.2017.09.008 (2017)
Physiological and pathophysiological implications of PGE2 and the PGE2 synthases in the kidney Wang, J; Liu, M; Zhang, X; Yang, G; Chen, L; Prostaglandins Other Lipid Mediat., DOI://10.1016/j.prostaglandins.2017.10.006 (2017)
Prediction of Host-Pathogen Interactions for Helicobacter pylori by Interface Mimicry and Implications to Gastric Cancer Guven-Maiorov, E; Tsai, CJ; Ma, B; Nussinov, R; J. Mol. Biol., DOI://10.1016/j.jmb.2017.10.023 (2017)
Independence between pre-mRNA splicing and DNA methylation in an isogenic minigene resource Kyster K. Nanan, Cody Ocheltree, David Sturgill, Mariana D. Mandler, Maria Prigge, Garima Varma, Shalini Oberdoerffer Nucleic Acids Res., doi://10.1093/nar/gkx900 (2017)
Analysis of Gap Times Based on Panel Count Data With Informative Observation Times and Unknown Start Time Ling Ma and Rajeshwari Sundaram J. Am. Stat. Assoc, doi://10.1080/01621459.2016.1246369 (2017)
Multimodal mapping of the brain's functional connectivity and the adult outcome of attention deficit hyperactivity disorder Sudre, G; Szekely, E; Sharp, W; Kasparek, S; Shaw, P; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1705229114 (2017)
The Kölliker-Fuse nucleus orchestrates the timing of expiratory abdominal nerve bursting Barnett, WH; Jenkin, SEM; Milsom, WK et al. J. Neurophysiol., DOI://10.1152/jn.00499.2017 (2017)
PaRSnIP: Sequence-Based Protein Solubility Prediction using Gradient Boosting Machine Rawi, R; Mall, R; Kunji, K; Shen, CH; Kwong, PD; Chuang, GY; Bioinformatics, DOI://10.1093/bioinformatics/btx662 (2017)
Subset- and tissue-defined STAT5 thresholds control homeostasis and function of innate lymphoid cells Villarino, AV; Sciumè, G; Davis, FP et al. J. Exp. Med., DOI://10.1084/jem.20150907 (2017)
Unpicking the determinants of amide NHO[double bond, length as m-dash]C hydrogen bond strength with diphenylacetylene molecular balances Luccarelli, J; Jones, IM; Thompson, S; Hamilton, AD; Org. Biomol. Chem., DOI://10.1039/c7ob02026k (2017)

Peptide dimerization-dissociation rates from replica exchange molecular dynamics Leahy, CT; Kells, A; Hummer, G; Buchete, NV; Rosta, E; J Chem Phys, DOI://10.1063/1.5004774 (2017)
Identification of UT-A1-and AQP2 interacting proteins in rat inner medullary collecting duct Chou, CL; Hwang, G; Hageman, DJ et al. Am. J. Physiol., Cell Physiol., DOI://10.1152/ajpcell.00082.2017 (2017)
Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex Guo, TW; Bartesaghi, A; Yang, H et al. Cell, DOI://10.1016/j.cell.2017.09.006 (2017)
How Many Protein Sequences Fold to a Given Structure? A Coevolutionary Analysis Tian, P; Best, RB; Biophys. J., DOI://10.1016/j.bpj.2017.08.039 (2017)
A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency Aoki, M; Hayashi, H; Rao, KV et al. Elife, DOI://10.7554/eLife.28020 (2017)
The FUT2 secretor variant p.Trp154Ter influences serum vitamin B12 concentration via holo-haptocorrin, but not holo-transcobalamin, and is associated with haptocorrin glycosylation Velkova, A; Diaz, JEL; Pangilinan, F et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddx369 (2017)

A functional connectivity-based neuromarker of sustained attention generalizes to predict recall in a reading task Jangraw, DC; Gonzalez-Castillo, J; Handwerker, DA et al. Neuroimage, DOI://10.1016/j.neuroimage.2017.10.019 (2017)
MELD: Mixed effects for large datasets Nielson, DM; Sederberg, PB; PLoS ONE, DOI://10.1371/journal.pone.0182797 (2017)
MicroRNA Signature of Cigarette Smoking and Evidence for a Putative Causal Role of MicroRNAs in Smoking-Related Inflammation and Target Organ Damage Willinger, CM; Rong, J; Tanriverdi, K et al. Circ Cardiovasc Genet, DOI://10.1161/CIRCGENETICS.116.001678 (2017)
De novo Assembly of a New Solanum pennellii Accession Using Nanopore Sequencing Schmidt, MH; Vogel, A; Denton, AK et al. Plant Cell, DOI://10.1105/tpc.17.00521 (2017)
Rapid Nanopore Sequencing of Plasmids and Resistance Gene Detection in Clinical Isolates Lemon, JK; Khil, PP; Frank, KM; Dekker, JP; J. Clin. Microbiol., DOI://10.1128/JCM.01069-17 (2017)
TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF Seberg, HE; Van Otterloo, E; Loftus, SK et al. PLoS Genet., DOI://10.1371/journal.pgen.1006636 (2017)

Molecular Dynamics Simulations of Ceramide and Ceramide-Phosphatidylcholine Bilayers Wang, E; Klauda, JB; J Phys Chem B, DOI://10.1021/acs.jpcb.7b08967 (2017)
CHD7 deficiency delays leukemogenesis in mice induced by CBFB-MYH11 Zhen, T; Kwon, E; Zhao, L et al. Blood, DOI://10.1182/blood-2017-04-780106 (2017)
Molecular architecture underlying fluid absorption by the developing inner ear Honda, K; Kim, SH; Kelly, MC et al. Elife, DOI://10.7554/eLife.26851 (2017)
Moderate blast exposure alters gene expression and levels of amyloid precursor protein Gill, J; Cashion, A; Osier, N et al. Neurol Genet, DOI://10.1212/NXG.0000000000000186 (2017)
Preclinical testing of the glycogen synthase kinase-3β inhibitor tideglusib for rhabdomyosarcoma Bharathy, N; Svalina, MN; Settelmeyer, TP et al. Oncotarget, DOI://10.18632/oncotarget.18520 (2017)
Novel near-diploid ovarian cancer cell line derived from a highly aneuploid metastatic ovarian tumor Rozenblum, E; Sotelo-Silveira, JR; Kim, GY et al. PLoS ONE, DOI://10.1371/journal.pone.0182610 (2017)

SMYD5 controls heterochromatin and chromosome integrity during embryonic stem cell differentiation Kidder, BL; He, R; Wangsa, D et al. Cancer Res., DOI://10.1158/0008-5472.CAN-17-0828 (2017)
GRL-09510, a Unique P2-Crown-Tetrahydrofuranylurethane -Containing HIV-1 Protease Inhibitor, Maintains Its Favorable Antiviral Activity against Highly-Drug-Resistant HIV-1 Variants in vitro Amano, M; Miguel Salcedo-Gómez, P; Yedidi, RS et al. Sci Rep, DOI://10.1038/s41598-017-12052-9 (2017)
Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains Murray, DT; Kato, M; Lin, Y et al. Cell, DOI://10.1016/j.cell.2017.08.048 (2017)
Piecewise Polynomial Approximations To The Icrp 116 Effective Dose Coefficients: Photons And Neutrons M. M. Mille N. E. Hertel P. M. Bergstrom C. Lee Radiation Protection Dosimetry, doi://10.1093/rpd/ncx112 (2017)
Estimating onset time from longitudinal and cross-sectional data with an application to estimating gestational age from longitudinal maternal anthropometry during pregnancy and neonatal anthropometry at birth Ana Maria Ortega-Villa, Katherine L. Grantz, Paul S. Albert J. Roy. Stat. Soc., DOI: 10.1111/rssa.12312 (2017)
Decline of long-range temporal correlations in the human brain during sustained wakefulness Meisel, C; Bailey, K; Achermann, P; Plenz, D; Sci Rep, DOI://10.1038/s41598-017-12140-w (2017)

Mechanisms of recognition of amyloid-β (Aβ) monomer, oligomer, and fibril by homologous antibodies Zhao, J; Nussinov, R; Ma, B; J. Biol. Chem., DOI://10.1074/jbc.M117.801514 (2017)
Topological structure determination of RNA using small angle X-ray scattering Bhandari, YR; Fan, L; Fang, X et al. J. Mol. Biol., DOI://10.1016/j.jmb.2017.09.006 (2017)
Nuclease activity gives an edge to host-defense peptide piscidin 3 over piscidin 1, rendering it more effective against persisters and biofilms Libardo, MDJ; Bahar, AA; Ma, B et al. FEBS J., DOI://10.1111/febs.14263 (2017)
Atropos: specific, sensitive, and speedy trimming of sequencing reads Didion, JP; Martin, M; Collins, FS; PeerJ, DOI://10.7717/peerj.3720 (2017)
Direct comparison of performance of single nucleotide variant calling in human genome with alignment-based and assembly-based approaches Wu, L; Yavas, G; Hong, H; Tong, W; Xiao, W; Sci Rep, DOI://10.1038/s41598-017-10826-9 (2017)
Paired Expression Analysis of Tumor Cell Surface Antigens Orentas, RJ; Sindiri, S; Duris, C et al. Front Oncol, DOI://10.3389/fonc.2017.00173 (2017)

Temporal interpolation alters motion in fMRI scans: Magnitudes and consequences for artifact detection Power, JD; Plitt, M; Kundu, P; Bandettini, PA; Martin, A; PLoS ONE, DOI://10.1371/journal.pone.0182939 (2017)
High-precision registration between zebrafish brain atlases using symmetric diffeomorphic normalization Marquart, GD; Tabor, KM; Horstick, EJ et al. Gigascience, DOI://10.1093/gigascience/gix056 (2017)
Global Inhibition with Specific Activation: How p53 and MYC Redistribute the Transcriptome in the DNA Double-Strand Break Response Porter, JR; Fisher, BE; Baranello, L et al. Mol. Cell, DOI://10.1016/j.molcel.2017.07.028 (2017)
Regulation of Noncoding Transcriptome in Developing Photoreceptors by Rod Differentiation Factor NRL Zelinger, L; Karakülah, G; Chaitankar, V et al. Invest. Ophthalmol. Vis. Sci., DOI://10.1167/iovs.17-21805 (2017)
Novel signal transducer and activator of transcription 1 mutation disrupts small ubiquitin-related modifier conjugation causing gain of function Sampaio, EP; Ding, L; Rose, SR et al. J. Allergy Clin. Immunol., DOI://10.1016/j.jaci.2017.07.027 (2017)
Higher-than-expected population prevalence of potentially pathogenic germline TP53 variants in individuals unselected for cancer history de Andrade, KC; Mirabello, L; Stewart, DR et al. Hum. Mutat., DOI://10.1002/humu.23320 (2017)
Statistical Methods for Standard Membrane-Feeding Assays to Measure Transmission Blocking or Reducing Activity in Malaria Bruce J. Swihart, Michael P. Fay & Kazutoyo Miura Journal of the American Statistical Association, doi://10.1080/01621459.2017.1356313 (2017)
The LDB1 Complex Co-opts CTCF for Erythroid Lineage-Specific Long-Range Enhancer Interactions Lee, J; Krivega, I; Dale, RK; Dean, A; Cell Rep, DOI://10.1016/j.celrep.2017.05.072 (2017)
MLL4 prepares the enhancer landscape for Foxp3 induction via chromatin looping Placek, K; Hu, G; Cui, K et al. Nat. Immunol., DOI://10.1038/ni.3812 (2017)
Therapeutic Antibodies to Ganglioside GD2 Evolved from Highly Selective Germline Antibodies Sterner, E; Peach, ML; Nicklaus, MC; Gildersleeve, JC; Cell Rep, DOI://10.1016/j.celrep.2017.07.050 (2017)
High-SETD8 inactivates p53 in neuroblastoma Veschi, V; Thiele, CJ; Oncoscience, DOI://10.18632/oncoscience.344 (2017)
Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation Kieffer-Kwon, KR; Nimura, K; Rao, SSP et al. Mol. Cell, DOI://10.1016/j.molcel.2017.07.013 (2017)

Anti-Inflammatory Chromatinscape Suggests Alternative Mechanisms of Glucocorticoid Receptor Action Oh, KS; Patel, H; Gottschalk, RA et al. Immunity, DOI://10.1016/j.immuni.2017.07.012 (2017)
Survival in adults and children with systemic lupus erythematosus: a systematic review and Bayesian meta-analysis of studies from 1950 to 2016 Tektonidou, MG; Lewandowski, LB; Hu, J; Dasgupta, A; Ward, MM; Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2017-211663 (2017)
Palmitoylation contributes to membrane curvature in Influenza A virus assembly and hemagglutinin-mediated membrane fusion Chlanda, P; Mekhedov, E; Waters, H et al. J. Virol., DOI://10.1128/JVI.00947-17 (2017)
Hydroxyl-radical footprinting combined with molecular modeling identifies unique features of DNA conformation and nucleosome positioning Alexey K. Shaytan, Hua Xiao, Grigoriy A. Armeev, Carl Wu, David Landsman, Anna R. Panchenko Nucleic Acids Res. , doi://10.1093/nar/gkx616 (2017)
Functional Subpopulations of Neurons in a Macaque Face Patch Revealed by Single-Unit fMRI Mapping Soo Hyun Park, Brian E. Russ, David B.T. McMahon, Kenji W. Koyano, Rebecca A. Berman, David A. Leopold Neuron, doi://10.1016/j.neuron.2017.07.014 (2017)
Stabilization of diastolic calcium signal via calcium pump regulation of complex local calcium releases and transient decay in a computational model of cardiac pacemaker cell with individual release channels Maltsev, AV; Maltsev, VA; Stern, MD; PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1005675 (2017)

Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity Monahan, Z; Ryan, VH; Janke, AM et al. EMBO J., DOI://10.15252/embj.201696394 (2017)
A very simple, re-executable neuroimaging publication Ghosh, SS; Poline, JB; Keator, DB et al. F1000Res, DOI://10.12688/f1000research.10783.2 (2017)
Katanin spiral and ring structures shed light on power stroke for microtubule severing Zehr, E; Szyk, A; Piszczek, G; Szczesna, E; Zuo, X; Roll-Mecak, A; Nat. Struct. Mol. Biol., DOI://10.1038/nsmb.3448 (2017)
Does accounting for seizure frequency variability increase clinical trial power Goldenholz, DM; Goldenholz, SR; Moss, R et al. Epilepsy Res., DOI://10.1016/j.eplepsyres.2017.07.013 (2017)
A Novel Method To Estimate Lymphocyte Dose And Application To Pediatric And Young Adult Ct Patients In The United Kingdom Choonsik Lee, Lindsay M. Morton, Amy Berrington de Gonzalez Radiation Dosimetry, doi://10.1093/rpd/ncx084 (2017)
Task-based dynamic functional connectivity: Recent findings and open questions Gonzalez-Castillo, J; Bandettini, PA; Neuroimage, DOI://10.1016/j.neuroimage.2017.08.006 (2017)

A common SLC26A4-linked haplotype underlying non-syndromic hearing loss with enlargement of the vestibular aqueduct Chattaraj, P; Munjal, T; Honda, K et al. J. Med. Genet., DOI://10.1136/jmedgenet-2017-104721 (2017)
Genetic background-dependent role of Egr1 for eyelid development Oh, J; Wang, Y; Chen, S et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1705848114 (2017)
A Two-Step Approach for Analysis of Nonignorable Missing Outcomes in Longitudinal Regression: an Application to Upstate KIDS Study Liu, D; Yeung, EH; McLain, AC; Xie, Y; Buck Louis, GM; Sundaram, R; Paediatr Perinat Epidemiol, DOI://10.1111/ppe.12382 (2017)
The prevalence of DICER1 pathogenic variation in population databases Kim, J; Field, A; Schultz, KAP; Hill, DA; Stewart, DR; Int. J. Cancer, DOI://10.1002/ijc.30907 (2017)
Systematic Investigation of Multi-TLR Sensing Identifies Regulators of Sustained Gene Activation in Macrophages Lin, B; Dutta, B; Fraser, IDC; Cell Syst, DOI://10.1016/j.cels.2017.06.014 (2017)
Combining Multiple Resting-State fMRI Features during Classification: Optimized Frameworks and Their Application to Nicotine Addiction Ding, X; Yang, Y; Stein, EA; Ross, TJ; Front Hum Neurosci, DOI://10.3389/fnhum.2017.00362 (2017)

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney Wain, LV; Vaez, A; Jansen, R et al. Hypertension, DOI://10.1161/HYPERTENSIONAHA.117.09438 (2017)
Neanderthal-Derived Genetic Variation Shapes Modern Human Cranium and Brain Gregory, MD; Kippenhan, JS; Eisenberg, DP et al. Sci Rep, DOI://10.1038/s41598-017-06587-0 (2017)
Genomic and metabolic characterization of a chromophobe renal cell carcinoma cell line model (UOK276) Yang, Y; Vocke, CD; Ricketts, CJ et al. Genes Chromosomes Cancer, DOI://10.1002/gcc.22476 (2017)
Genome Organization Drives Chromosome Fragility Canela, A; Maman, Y; Jung, S et al. Cell, DOI://10.1016/j.cell.2017.06.034 (2017)
A population-specific reference panel empowers genetic studies of Anabaptist populations Hou, L; Kember, RL; Roach, JC et al. Sci Rep, DOI://10.1038/s41598-017-05445-3 (2017)
Global alteration of the drug-binding pocket of human P-glycoprotein (ABCB1) by substitution of fifteen conserved residues reveals a negative correlation between substrate size and transport efficiency Vahedi, S; Chufan, EE; Ambudkar, SV; Biochem. Pharmacol., DOI://10.1016/j.bcp.2017.07.014 (2017)

Histone demethylases UTX and JMJD3 are required for NKT cell development in mice Northrup, D; Yagi, R; Cui, K et al. Cell Biosci, DOI://10.1186/s13578-017-0152-8 (2017)
Facultative CTCF sites moderate mammary super-enhancer activity and regulate juxtaposed gene in non-mammary cells Willi, M; Yoo, KH; Reinisch, F et al. Nat Commun, DOI://10.1038/ncomms16069 (2017)
How to control for unmeasured confounding in an observational time-to-event study with exposure incidence information: the treatment choice Cox model Troendle, J; Leifer, E; Zhang, Z; Yong, S; Tewes, H Stat. Med. , DOI: 10.1002/sim.7377 (2017)
Chromosome 3q22-29 amplification is linked to increased expression of multiple genes in key pathways deregulated in head and neck cancer tumors and cell lines Cheng H, Yang X, Si H et al. Cancer Research, DOI: 10.1158/1538-7445.AM2017-4374 (2017)
Deep Learning and Convolutional Neural Networks for Medical Image Computing: Precision Medicine, High Performance and Large-Scale Datasets edited by Le Lu, Yefeng Zheng, Gustavo Carneiro, Lin Yang Advances in Computer Vision and Pattern Recognition (2017)
Scaffolding of long read assemblies using long range contact information Ghurye, J; Pop, M; Koren, S; Bickhart, D; Chin, CS; BMC Genomics, DOI://10.1186/s12864-017-3879-z (2017)

Proper joint analysis of summary association statistics requires the adjustment of heterogeneity in SNP coverage pattern Han Zhang, William Wheeler, Lei Song, Kai Yu Briefings in Bioinformatics, doi://10.1093/bib/bbx072 (2017)
Oncogenic Activation of the RNA Binding Protein NELFE and MYC Signaling in Hepatocellular Carcinoma Dang, H; Takai, A; Forgues, M et al. Cancer Cell, DOI://10.1016/j.ccell.2017.06.002 (2017)
Longitudinal profiling reveals a persistent intestinal dysbiosis triggered by conventional anti-tuberculosis therapy Namasivayam, S; Maiga, M; Yuan, W et al. Microbiome, DOI://10.1186/s40168-017-0286-2 (2017)
Computer algorithms for automated detection and analysis of local Ca2+ releases in spontaneously beating cardiac pacemaker cells Maltsev, AV; Parsons, SP; Kim, MS et al. PLoS ONE, DOI://10.1371/journal.pone.0179419 (2017)
Staphylococcus aureus and Staphylococcus epidermidis strain diversity underlying pediatric atopic dermatitis Byrd, AL; Deming, C; Cassidy, SKB et al. Sci Transl Med, DOI://10.1126/scitranslmed.aal4651 (2017)
Genomic Analyses Reveal the Influence of Geographic Origin, Migration, and Hybridization on Modern Dog Breed Development Parker, HG; Dreger, DL; Rimbault, M et al. Cell Rep, DOI://10.1016/j.celrep.2017.03.079 (2017)

Clusters of calcium release channels harness the Ising phase transition to confine their elementary intracellular signals Maltsev, AV; Maltsev, VA; Stern, MD; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1701409114 (2017)
Pattern-mixture models with incomplete informative cluster size: application to a repeated pregnancy study Ashok Chaurasia, Danping Liu, Paul S. Albert Royal Statistical Society: Applied Statistics, DOI: 10.1111/rssc.12226 (2017)
Biopsy-guided learning with deep convolutional neural networks for Prostate Cancer detection on multiparametric MRI Tsehay Y, Lay N et al Biomedical Imaging, doi://10.1109/ISBI.2017.7950602 (2017)
Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers Steve TR, Li W-Q, Shi J, et al. Hum. Mol. Genet. , DOI: https://doi.org/10.1093/hmg/ddx188 (2017)
Type 2 diabetes, glucose, insulin, BMI, and ischemic stroke subtypes: Mendelian randomization study Larsson, SC; Scott, RA; Traylor, M et al. Neurology, DOI://10.1212/WNL.0000000000004173 (2017)
Whole-Genome Sequencing Overrules a Suspected Case of Carbapenem-Resistant Enterobacter cloacae Transmission Chen, M; Conlan, S; Lau, AF et al. J. Clin. Microbiol., DOI://10.1128/JCM.00915-17 (2017)

Defining the Neural Substrate of the Adult Outcome of Childhood ADHD: A Multimodal Neuroimaging Study of Response Inhibition Szekely, E; Sudre, GP; Sharp, W; Leibenluft, E; Shaw, P; Am J Psychiatry, DOI://10.1176/appi.ajp.2017.16111313 (2017)
Growth Inhibition of Colon Cancer and Melanoma Cells by Versiol Derivatives from a Paraconiothyrium Species Cho, N; Ransom, TT; Sigmund, J et al. J. Nat. Prod., DOI://10.1021/acs.jnatprod.7b00170 (2017)
De novo transcriptome assembly of loggerhead sea turtle nesting of the Colombian Caribbean Hernández-Fernández, J; Pinzón, A; Mariño-Ramírez, L; Genom Data, DOI://10.1016/j.gdata.2017.06.005 (2017)
Conserved and species-specific molecular denominators in mammalian skeletal muscle aging Mercken, EM; Capri, M; Carboneau, BA et al. NPJ Aging Mech Dis, DOI://10.1038/s41514-017-0009-8 (2017)
Pandemic (H1N1) 2009 influenza A virus infection associated with respiratory signs in sloth bears (Melursus ursinus) Boedeker, NC; Nelson, MI; Killian, ML; Torchetti, MK; Barthel, T; Murray, S; Zoonoses Public Health, DOI://10.1111/zph.12370 (2017)
Characterizing cis-regulatory variation in the transcriptome of histologically normal and tumor-derived pancreatic tissues Zhang, M; Lykke-Andersen, S; Zhu, B et al. Gut, DOI://10.1136/gutjnl-2016-313146 (2017)
Actin Filament Strain Promotes Severing and Cofilin Dissociation Schramm, AC; Hocky, GM; Voth, GA; Blanchoin, L; Martiel, JL; De La Cruz, EM; Biophys. J., DOI://10.1016/j.bpj.2017.05.016 (2017)
Insights into the binding mode of MEK type-III inhibitors. A step towards discovering and designing allosteric kinase inhibitors across the human kinome Zhao, Z; Xie, L; Bourne, PE; PLoS ONE, DOI://10.1371/journal.pone.0179936 (2017)
Genome-Wide Association Study to Identify Susceptibility Loci That Modify Radiation-Related Risk for Breast Cancer After Childhood Cancer Lindsay M. Morton Joshua N. Sampson Gregory T. Armstrong et al. J. Natl. Cancer. Inst., DOI: https://doi.org/10.1093/jnci/djx058 (2017)
The Transcription Factor T-bet Limits Amplification of Type I IFN Transcriptome and Circuitry in T Helper 1 Cells Iwata, S; Mikami, Y; Sun, HW et al. Immunity, DOI://10.1016/j.immuni.2017.05.005 (2017)
Flexible-Body Motions of Calmodulin and the Farnesylated Hypervariable Region Yield a High-Affinity Interaction Enabling K-Ras4B Membrane Extraction Jang, H; Banerjee, A; Chavan, T; Gaponenko, V; Nussinov, R; J. Biol. Chem., DOI://10.1074/jbc.M117.785063 (2017)
The Transcriptome of the Didelphis virginiana Opossum Kidney OK Proximal Tubule Cell Line Eshbach, ML; Sethi, R; Avula, R et al. Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00228.2017 (2017)

Graphite-Templated Amyloid Nanostructures Formed by A Potential Pentapeptide Inhibitor for Alzheimer's disease: A Combined Study of Real-Time Atomic Force Microscopy and Molecular Dynamics Simulations Li, N; Jang, H; Yuan, M et al. Langmuir, DOI://10.1021/acs.langmuir.7b00414 (2017)
Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study Noyce, AJ; Kia, DA; Hemani, G et al. PLoS Med., DOI://10.1371/journal.pmed.1002314 (2017)
Socioeconomic disadvantage, gestational immune activity, and neurodevelopment in early childhood Gilman, SE; Hornig, M; Ghassabian, A et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1617698114 (2017)
Workflow and web application for annotating NCBI BioProject transcriptome data Vera Alvarez, R; Medeiros Vidal, N; Garzón-Martínez, GA; Barrero, LS; Landsman, D; Mariño-Ramírez, L; Database (Oxford), DOI://10.1093/database/bax008 (2017)
NeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases Blauwendraat, C; Faghri, F; Pihlstrom, L et al. Neurobiol. Aging, DOI://10.1016/j.neurobiolaging.2017.05.009 (2017)
Overexpression of ATP-Binding Cassette Subfamily G Member 2 Confers Resistance to Phosphatidylinositol 3-Kinase Inhibitor PF-4989216 in Cancer Cells Wu, CP; Murakami, M; Hsiao, SH et al. Mol. Pharm., DOI://10.1021/acs.molpharmaceut.7b00277 (2017)

Intrinsic protein disorder in oncogenic KRAS signaling Nussinov, R; Jang, H; Tsai, CJ et al. Cell. Mol. Life Sci., DOI://10.1007/s00018-017-2564-3 (2017)
Mitochondrial respiration and ROS emission during β-oxidation in the heart: An experimental-computational study Cortassa, S; Sollott, SJ; Aon, MA; PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1005588 (2017)
Heightened amygdala responsiveness in s-carriers of 5-HTTLPR genetic polymorphism reflects enhanced cortical rather than subcortical inputs: An MEG study Luo, Q; Holroyd, T; Mitchell, D et al. Hum Brain Mapp, DOI://10.1002/hbm.23616 (2017)
Monte Carlo simulations of randomized clinical trials in epilepsy DM Goldenholz, J Tharayil, R Moss, E Myers, WH Theodore Annals of Clinical and Translational Neurology, DOI: 10.1002/acn3.426 (2017)
Prostate Cancer: A Correlative Study of Multiparametric MR Imaging and Digital Histopathology Kwak, JT; Sankineni, S; Xu, S et al. Radiology, DOI://10.1148/radiol.2017160906 (2017)
Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31 Freeman, LA; Demosky, SJ; Konaklieva, M et al. J. Pharmacol. Exp. Ther., DOI://10.1124/jpet.117.240457 (2017)
High-fidelity PCR enzyme with DNA-binding domain facilitates de novo gene synthesis Dolgova, AS; Stukolova, OA; 3 Biotech, DOI://10.1007/s13205-017-0745-2 (2017)
Mediator binds to boundaries of chromosomal interaction domains and to proteins involved in DNA looping, RNA metabolism, chromatin remodeling, and actin assembly Chereji, RV; Bharatula, V; Elfving, N et al. Nucleic Acids Res., DOI://10.1093/nar/gkx491 (2017)
Release of Cytochrome C from Bax Pores at the Mitochondrial Membrane Zhang, M; Zheng, J; Nussinov, R; Ma, B; Sci Rep, DOI://10.1038/s41598-017-02825-7 (2017)
Threat of shock increases excitability and connectivity of the intraparietal sulcus Balderston, NL; Hale, E; Hsiung, A et al. Elife, DOI://10.7554/eLife.23608 (2017)
Identification and Analysis of Protein Phosphorylation by Mass Spectrometry DE McNulty, TW Sikorski, RS Annan in 'Analysis of Protein Post-Translational Modifications by , ed John R. Griffiths, Richard D. Unwin. Wiley (2017)
Whole-brain connectivity dynamics reflect both task-specific and individual-specific modulation: A multitask study Xie, H; Calhoun, VD; Gonzalez-Castillo, J et al. Neuroimage, DOI://10.1016/j.neuroimage.2017.05.050 (2017)

Phosphorylated SIRT1 associates with replication origins to prevent excess replication initiation and preserve genomic stability Utani, K; Fu, H; Jang, SM et al. Nucleic Acids Res., DOI://10.1093/nar/gkx468 (2017)
Combined single molecule experimental and computational approaches for understanding the unfolding pathway of a viral translation enhancer that participates in a conformational switch Le, MT; Kasprzak, WK; Shapiro, BA; Simon, AE; RNA Biol, DOI://10.1080/15476286.2017.1325069 (2017)
Tumor-Infiltrating Lymphocyte Therapy and Neoantigens Robbins, PF Cancer J, DOI://10.1097/PPO.0000000000000267 (2017)
Deficiency of Complement 1r Subcomponent in Early-Onset Systemic Lupus Erythematosus: The Role of Disease-Modifying Alleles in a Monogenic Disease Demirkaya, E; Zhou, Q; Smith, CK et al. , DOI://10.1002/art.40158 (2017)
Dynamic enhancer function in the chromatin context Goldstein, I; Hager, GL; Wiley Interdiscip Rev Syst Biol Med, DOI://10.1002/wsbm.1390 (2017)
PDEδ Binding to Ras Isoforms Provides a Route to Proper Membrane Localization Muratcioglu, S; Jang, H; Gursoy, A; Keskin, O; Nussinov, R; J Phys Chem B, DOI://10.1021/acs.jpcb.7b03035 (2017)

Bivariate Genomic Footprinting Detects Changes in Transcription Factor Activity Baek, S; Goldstein, I; Hager, GL; Cell Rep, DOI://10.1016/j.celrep.2017.05.003 (2017)
Mechanics of post-fusion exocytotic vesicle Stephens, T; Wu, Z; Liu, J; Phys Biol, DOI://10.1088/1478-3975/aa6ad6 (2017)
BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency Afzali, B; Grönholm, J; Vandrovcova, J et al. Nat. Immunol., DOI://10.1038/ni.3753 (2017)
Brownian ratchet mechanisms of ParA-mediated partitioning Hu, L; Vecchiarelli, AG; Mizuuchi, K; Neuman, KC; Liu, J; Plasmid, DOI://10.1016/j.plasmid.2017.05.002 (2017)
Pathology of callosal damage in ALS: An ex-vivo, 7 T diffusion tensor MRI study Agustin M. Cardenas, Joelle E. Sarlls, Justin Y. Kwan, Devin Bageac, Zachary S. Gala, Laura E. Danielian, Abhik Ray-Chaudhury, Hao-Wei Wang, Karla L. Miller, Sean Foxley, Saad Jbabdid, Robert C. Welsh, Mary Kay Floeter NeuroImage: Clinical, doi://10.1016/j.nicl.2017.04.024 (2017)
Unsupervised Joint Mining of Deep Features and Image Labels for Large-Scale Radiology Image Categorization and Scene Recognition Xiaosong Wang, Le Lu, Hoo-chang Shin, Lauren Kim, Mohammadhadi Bagheri, Isabella Nogues, Jianhua Yao, Ronald M. Summers IEEE Winter Conference on Applications of Computer Vision, DOI 10.1109/WACV.2017.116 (2017)

Simulating clinical trials with and without intracranial EEG data Goldenholz D, Tharayil J, Kuzniecky R, et al. Epilepsia Open, DOI: 10.1002/epi4.12038 (2017)
Drosophila melanogaster positive transcriptional elongation factors regulate metabolic and sex-biased expression in adults Yang, H; Basquin, D; Pauli, D; Oliver, B; BMC Genomics, DOI://10.1186/s12864-017-3755-x (2017)
Pias3 is necessary for dorso-ventral patterning and visual response of retinal cones but is not required for rod photoreceptor differentiation Campla, CK; Breit, H; Dong, L; Gumerson, JD; Roger, JE; Swaroop, A; Biol Open, DOI://10.1242/bio.024679 (2017)
Human ancestry correlates with language and reveals that race is not an objective genomic classifier Baker, JL; Rotimi, CN; Shriner, D; Sci Rep, DOI://10.1038/s41598-017-01837-7 (2017)
Conformational Changes in Active and Inactive States of Human PP2Cα Characterized by Hydrogen/Deuterium Exchange-Mass Spectrometry Mazur, SJ; Gallagher, ES; Debnath, S et al. Biochemistry, DOI://10.1021/acs.biochem.6b01220 (2017)
A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated with Reduced Energy Expenditure in American Indians Piaggi, P; Masindova, I; Muller, YL et al. Diabetes, DOI://10.2337/db16-1565 (2017)

Molecular codes for cell type specification in Brn3 retinal ganglion cells Sajgo, S; Ghinia, MG; Brooks, M et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1618551114 (2017)
A population MRI brain template and analysis tools for the macaque Seidlitz, J; Sponheim, C; Glen, D et al. Neuroimage, DOI://10.1016/j.neuroimage.2017.04.063 (2017)
Calmodulin and PI3K Signaling in KRAS Cancers Nussinov, R; Wang, G; Tsai, CJ et al. Trends Cancer, DOI://10.1016/j.trecan.2017.01.007 (2017)
fastMitoCalc: an ultra-fast program to estimate mitochondrial DNA copy number from whole-genome sequences Qian, Y; Butler, TJ; Opsahl-Ong, K et al. Bioinformatics, DOI://10.1093/bioinformatics/btw835 (2017)
Median Analysis of Repeated Measures Associated with Recurrent Events in Presence of Terminal Event Sundaram, R; Ma, L; Ghoshal, S; Int J Biostat, DOI://10.1515/ijb-2016-0057 (2017)
The isomeric preference of an atypical dopamine transporter inhibitor contributes to its selection of the transporter conformation Abramyan, AM; Stolzenberg, S; Li, Z; Loland, CJ; Noé, F; Shi, L; ACS Chem Neurosci, DOI://10.1021/acschemneuro.7b00094 (2017)

Behavioral and Neural Sustained Attention Deficits in Disruptive Mood Dysregulation Disorder and Attention-Deficit/Hyperactivity Disorder Pagliaccio, D; Wiggins, JL; Adleman, NE et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2017.02.008 (2017)
Synthesis of Dopamine in E.coli Using Plasmid Based Expression System and Its Marked Effect on Host Growth Profiles Das, A; Verma, A; Mukherjee, KJ; Prep. Biochem. Biotechnol., DOI://10.1080/10826068.2017.1320291 (2017)
Immunocompetent mouse allograft models for development of therapies to target breast cancer metastasis Yang, Y; Yang, HH; Hu, Y et al. Oncotarget, DOI://10.18632/oncotarget.15695 (2017)
Transposable elements in the Anopheles funestus transcriptome Fernández-Medina, RD; Carareto, CMA; Struchiner, CJ; Ribeiro, JMC; Genetica, DOI://10.1007/s10709-017-9964-z (2017)
fMRI clustering and false-positive rates Cox, RW; Chen, G; Glen, DR; Reynolds, RC; Taylor, PA; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1614961114 (2017)
Sequence and Structural Analyses Reveal Distinct and Highly Diverse Human CD8(+) TCR Repertoires to Immunodominant Viral Antigens Chen, G; Yang, X; Ko, A et al. Cell Rep, DOI://10.1016/j.celrep.2017.03.072 (2017)

Power Grid Protection of the Muscle Mitochondrial Reticulum Glancy, B; Hartnell, LM; Combs, CA et al. Cell Rep, DOI://10.1016/j.celrep.2017.03.063 (2017)
Brain-derived neurotrophic factor Val(66)Met genotype and ovarian steroids interactively modulate working memory-related hippocampal function in women: a multimodal neuroimaging study Wei, SM; Baller, EB; Kohn, PD et al. Mol. Psychiatry, DOI://10.1038/mp.2017.72 (2017)
The Molecular Revolution in Cutaneous Biology: Investigating the Skin Microbiome Kong, HH; Segre, JA; J. Invest. Dermatol., DOI://10.1016/j.jid.2016.07.045 (2017)
Brownian Ratchet Mechanism for Faithful Segregation of Low-Copy-Number Plasmids Hu, L; Vecchiarelli, AG; Mizuuchi, K; Neuman, KC; Liu, J; Biophys. J., DOI://10.1016/j.bpj.2017.02.039 (2017)
H3K4 demethylase KDM5B regulates global dynamics of transcription elongation and alternative splicing in embryonic stem cells He, R; Kidder, BL; Nucleic Acids Res., DOI://10.1093/nar/gkx251 (2017)
FMRI Clustering in AFNI: False-Positive Rates Redux Cox, RW; Chen, G; Glen, DR; Reynolds, RC; Taylor, PA; Brain Connect, DOI://10.1089/brain.2016.0475 (2017)

A novel perivascular cell population in the zebrafish brain Venero Galanternik, M; Castranova, D; Gore, AV et al. Elife, DOI://10.7554/eLife.24369 (2017)
Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly Schneider, VA; Graves-Lindsay, T; Howe, K et al. Genome Res., DOI://10.1101/gr.213611.116 (2017)
Intrinsic Functional Connectivity of the Central Nucleus of the Amygdala and Bed Nucleus of the Stria Terminalis Gorka, AX; Torrisi, S; Shackman, AJ; Grillon, C; Ernst, M; Neuroimage, DOI://10.1016/j.neuroimage.2017.03.007 (2017)
Hydrophobic-Hydrophilic Forces in Protein Folding Durell, SR; Ben-Naim, A; Biopolymers, DOI://10.1002/bip.23020 (2017)
Molecular convergence in ex vivo models of Diamond-Blackfan anemia O'Brien, KA; Farrar, JE; Vlachos, A et al. Blood, DOI://10.1182/blood-2017-01-760462 (2017)
Detection of genetic loci associated with plasma fetuin-A: A meta-analysis of genome-wide association studies from the CHARGE Consortium Jensen, MK; Jensen, RA; Mukamal, KJ et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddx091 (2017)

A New Natural Product Analog of Blasticidin S Reveals Cellular Uptake Facilitated by the NorA Multidrug Transporter Davison, JR; Lohith, KM; Wang, X et al. Antimicrob. Agents Chemother., DOI://10.1128/AAC.02635-16 (2017)
Retrospective correction of frequency drift in spectral editing: The GABA editing example van der Veen, JW; Marenco, S; Berman, KF; Shen, J; NMR Biomed, DOI://10.1002/nbm.3725 (2017)
A big data approach to the development of mixed-effects models for seizure count data Tharayil, JJ; Chiang, S; Moss, R; Stern, JM; Theodore, WH; Goldenholz, DM; Epilepsia, DOI://10.1111/epi.13727 (2017)
Engineering efficient production of itaconic acid from diverse substrates in Escherichia coli Chang, P; Chen, GS; Chu, HY; Lu, KW; Shen, CR; J. Biotechnol., DOI://10.1016/j.jbiotec.2017.03.026 (2017)
REEP6 mediates trafficking of a subset of Clathrin-coated vesicles and is critical for rod photoreceptor function and survival Veleri, S; Nellissery, J; Mishra, B et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddx111 (2017)
Multi-echo fMRI: A review of applications in fMRI denoising and analysis of BOLD signals Kundu, P; Voon, V; Balchandani, P; Lombardo, MV; Poser, BA; Bandettini, PA; Neuroimage, DOI://10.1016/j.neuroimage.2017.03.033 (2017)

Stable functional networks exhibit consistent timing in the human brain Chapeton, JI; Inati, SK; Zaghloul, KA; Brain, DOI://10.1093/brain/aww337 (2017)
Characterization of four arginine kinases in the ciliate Paramecium tetraurelia: Investigation on the substrate inhibition mechanism Yano, D; Suzuki, T; Hirokawa, S; Fuke, K; Suzuki, T; Int. J. Biol. Macromol., DOI://10.1016/j.ijbiomac.2017.03.133 (2017)
An investigation of doubt in obsessive-compulsive disorder Samuels, J; Bienvenu, OJ; Krasnow, J et al. Compr Psychiatry, DOI://10.1016/j.comppsych.2017.03.004 (2017)
Gramicidin A Channel Formation Induces Local Lipid Redistribution II: A 3D Continuum Elastic Model Sodt, AJ; Beaven, AH; Andersen, OS; Im, W; Pastor, RW; Biophys. J., DOI://10.1016/j.bpj.2017.01.035 (2017)
APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast Saini, N; Roberts, SA; Sterling, JF; Malc, EP; Mieczkowski, PA; Gordenin, DA; DNA Repair (Amst.), DOI://10.1016/j.dnarep.2017.03.003 (2017)
Automatic MR prostate segmentation by deep learning with holistically-nested networks Ruida Cheng ; Holger R. Roth ; Nathan Lay ; Le Lu ; Baris Turkbey ; William Gandler ; Evan S. McCreedy ; Peter Choyke ; Ronald M. Summers ; Matthew J. McAuliffe Proc. SPIE 10133, Medical Imaging 2017, doi:10.1117/12.2254558 (2017)

Macrophilone A: Structure Elucidation, Total Synthesis, and Functional Evaluation of a Biologically Active Iminoquinone from the Marine Hydroid Macrorhynchia philippina Zlotkowski, K; Hewitt, WM; Yan, P et al. Org. Lett., DOI://10.1021/acs.orglett.7b00496 (2017)
Common and rare exonic MUC5B variants associated with type 2 diabetes in Han Chinese Chen, G; Zhang, Z; Adebamowo, SN et al. PLoS ONE, DOI://10.1371/journal.pone.0173784 (2017)
Korean Pediatric and Adult Head Computational Phantoms and Application to Photon Specific Absorbed Fractions Calculations Villoing, D; McMillan, D; Kim, KP et al. Radiat Prot Dosimetry, DOI://10.1093/rpd/ncx009 (2017)
Expressed Structurally-stable Inverted Duplicates in Mammalian Genomes as Functional Noncoding Elements Chen, ZX; Oliver, B; Zhang, YE; Gao, G; Long, M; Genome Biol Evol, DOI://10.1093/gbe/evx054 (2017)
Flexible CRISPR library construction using parallel oligonucleotide retrieval Read, A; Gao, S; Batchelor, E; Luo, J; Nucleic Acids Res., DOI://10.1093/nar/gkx181 (2017)
Functional assessment of CTCF sites at cytokine-sensing mammary enhancers using CRISPR/Cas9 gene editing in mice Lee, HK; Willi, M; Wang, C et al. Nucleic Acids Res., DOI://10.1093/nar/gkx185 (2017)

DNase-active TREX1 frame-shift mutants induce serologic autoimmunity in mice Sakai, T; Miyazaki, T; Shin, DM et al. J. Autoimmun., DOI://10.1016/j.jaut.2017.03.001 (2017)
Determining Cysteines Available for Covalent Inhibition Across the Human Kinome Zhao, Z; Liu, Q; Bliven, S; Xie, L; Bourne, PE; J. Med. Chem., DOI://10.1021/acs.jmedchem.6b01815 (2017)
Whole-Exome Sequencing for Diagnosis of Turner Syndrome: Toward Next-Generation Sequencing and Newborn Screening Murdock, DR; Donovan, FX; Chandrasekharappa, SC et al. J. Clin. Endocrinol. Metab., DOI://10.1210/jc.2016-3414 (2017)
The Role of TM5 in Na2 Release and the Conformational Transition of Neurotransmitter:Sodium Symporters toward the Inward-Open State Stolzenberg, S; Li, Z; Quick, M et al. J. Biol. Chem., DOI://10.1074/jbc.M116.757153 (2017)
Neuroanatomic, epigenetic and genetic differences in monozygotic twins discordant for attention deficit hyperactivity disorder Chen, YC; Sudre, G; Sharp, W et al. Mol. Psychiatry, DOI://10.1038/mp.2017.45 (2017)
Predicting drug-drug interactions through drug structural similarities and interaction networks incorporating pharmacokinetics and pharmacodynamics knowledge Takeda, T; Hao, M; Cheng, T; Bryant, SH; Wang, Y; J Cheminform, DOI://10.1186/s13321-017-0200-8 (2017)

Modulation of opioid receptor affinity and efficacy via N-substitution of 9β-hydroxy-5-(3-hydroxyphenyl)morphan: Synthesis and computer simulation study Truong, PM; Hassan, SA; Lee, YS et al. Bioorg. Med. Chem., DOI://10.1016/j.bmc.2017.02.064 (2017)
Computational Study of the Forces Driving Aggregation of Ultrasmall Nanoparticles in Biological Fluids Hassan, SA ACS Nano, DOI://10.1021/acsnano.7b00981 (2017)
Identification of β-Catenin-Interacting Proteins in Nuclear Fractions of Native Rat Collecting Duct Cells Hwang, JR; Chou, CL; Medvar, B; Knepper, MA; Jung, HJ; Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00054.2017 (2017)
Canu: scalable and accurate long-read assembly via adaptive k-mer weighting and repeat separation Koren, S; Walenz, BP; Berlin, K; Miller, JR; Bergman, NH; Phillippy, AM; Genome Res., DOI://10.1101/gr.215087.116 (2017)
Whole exome sequencing in the Framingham Heart Study identifies rare variation in HYAL2 that influences platelet aggregation Eicher, JD; Chen, MH; Pitsillides, AN et al. Thromb. Haemost., DOI://10.1160/TH16-09-0677 (2017)
BTBD18 Regulates a Subset of piRNA-Generating Loci through Transcription Elongation in Mice Zhou, L; Canagarajah, B; Zhao, Y et al. Dev. Cell, DOI://10.1016/j.devcel.2017.02.007 (2017)
A large outbreak of acute gastroenteritis in Shippensburg, Pennsylvania, 1972 revisited: evidence for common source exposure to a recombinant GII.Pg/GII.3 norovirus Johnson, JA; Parra, GI; Levenson, EA; Green, KY; Epidemiol. Infect., DOI://10.1017/S0950268817000498 (2017)
Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits Yao, C; Joehanes, R; Johnson, AD et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2017.02.003 (2017)
Effect of Detergent Micelle Environment on P-glycoprotein (ABCB1)-Ligand Interactions Shukla, S; Abel, B; Chufan, EE; Ambudkar, SV; J. Biol. Chem., DOI://10.1074/jbc.M116.771634 (2017)
Single-molecule sequencing and chromatin conformation capture enable de novo reference assembly of the domestic goat genome Bickhart, DM; Rosen, BD; Koren, S et al. Nat. Genet., DOI://10.1038/ng.3802 (2017)
Analysis of large versus small dogs reveals three genes on the canine X chromosome associated with body weight, muscling and back fat thickness Plassais, J; Rimbault, M; Williams, FJ; Davis, BW; Schoenebeck, JJ; Ostrander, EA; PLoS Genet., DOI://10.1371/journal.pgen.1006661 (2017)
SMYD5 regulates H4K20me3-marked heterochromatin to safeguard ES cell self-renewal and prevent spurious differentiation Kidder, BL; Hu, G; Cui, K; Zhao, K; Epigenetics Chromatin, DOI://10.1186/s13072-017-0115-7 (2017)
Genome-wide siRNA screen of genes regulating the LPS-induced TNF-α response in human macrophages Sun, J; Katz, S; Dutta, B; Wang, Z; Fraser, ID; Sci Data, DOI://10.1038/sdata.2017.7 (2017)
Genome-wide siRNA screen of genes regulating the LPS-induced NF-κB and TNF-α responses in mouse macrophages Li, N; Katz, S; Dutta, B; Benet, ZL; Sun, J; Fraser, ID; Sci Data, DOI://10.1038/sdata.2017.8 (2017)
Permanganate/S1 Nuclease Footprinting Reveals Non-B DNA Structures with Regulatory Potential across a Mammalian Genome Kouzine, F; Wojtowicz, D; Baranello, L et al. Cell Syst, DOI://10.1016/j.cels.2017.01.013 (2017)
Circulating tumor cells capture disease evolution in advanced prostate cancer Lack, J; Gillard, M; Cam, M; Paner, GP; VanderWeele, DJ; J Transl Med, DOI://10.1186/s12967-017-1138-3 (2017)
Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer Liu, Q; Acharya, P; Dolan, MA et al. Nat. Struct. Mol. Biol., DOI://10.1038/nsmb.3382 (2017)
The effects of shared information on semantic calculations in the gene ontology Bible, PW; Sun, HW; Morasso, MI; Loganantharaj, R; Wei, L; Comput Struct Biotechnol J, DOI://10.1016/j.csbj.2017.01.009 (2017)

Ultra-High-Field fMRI Reveals a Role for the Subiculum in Scene Perceptual Discrimination Hodgetts, CJ; Voets, NL; Thomas, AG; Clare, S; Lawrence, AD; Graham, KS; J. Neurosci., DOI://10.1523/JNEUROSCI.3225-16.2017 (2017)
Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies Hedman, ÅK; Mendelson, MM; Marioni, RE et al. Circ Cardiovasc Genet, DOI://10.1161/CIRCGENETICS.116.001487 (2017)
Circulating miRNA Associated with Posttraumatic Stress Disorder in a Cohort of Military Combat Veterans Christiana G. Martin, Hyungsuk Kim, Sijung Yun, Whitney Livingston, Joseph Fetta, Vincent Mysliwiec, Tristin Baxter, Jessica M. Gill Psychiatry Research, doi://10.1016/j.psychres.2017.01.081 (2017)
The dynamic mechanism of RASSF5 and MST kinase activation by Ras Liao, TJ; Jang, H; Tsai, CJ; Fushman, D; Nussinov, R; Phys Chem Chem Phys, DOI://10.1039/c6cp08596b (2017)
Genome-Wide Identification of Basic Helix-Loop-Helix and NF-1 Motifs Underlying GR Binding Sites in Male Rat Hippocampus Pooley, JR; Flynn, BP; Grøntved, L et al. Endocrinology, DOI://10.1210/en.2016-1929 (2017)
Somatic mutations in murine models of leukemia and lymphoma: Disease specificity and clinical relevance Goldberg, L; Gough, SM; Lee, F et al. Genes Chromosomes Cancer, DOI://10.1002/gcc.22451 (2017)
Multivariate meta-analysis with an increasing number of parameters Boca, SM; Pfeiffer, RM; Sampson, JN; Biom J, DOI://10.1002/bimj.201600013 (2017)
Anopheline salivary protein genes and gene families: an evolutionary overview after the whole genome sequence of sixteen Anopheles species Arcà, B; Lombardo, F; Struchiner, CJ; Ribeiro, JM; BMC Genomics, DOI://10.1186/s12864-017-3579-8 (2017)
Genetic regulatory signatures underlying islet gene expression and type 2 diabetes Varshney, A; Scott, LJ; Welch, RP et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1621192114 (2017)
A novel DLX3-PKC integrated signaling network drives keratinocyte differentiation Palazzo, E; Kellett, MD; Cataisson, C et al. Cell Death Differ., DOI://10.1038/cdd.2017.5 (2017)
Folding behavior of a T-shaped, ribosome-binding translation enhancer implicated in a wide-spread conformational switch Le, MT; Kasprzak, WK; Kim, T et al. Elife, DOI://10.7554/eLife.22883 (2017)
Thiazole-valine peptidomimetic (TTT-28) antagonizes multidrug resistance in vitro and in vivo by selectively inhibiting the efflux activity of ABCB1 Wang, YJ; Patel, BA; Anreddy, N et al. Sci Rep, DOI://10.1038/srep42106 (2017)

Messenger RNA and MicroRNA transcriptomic signatures of cardiometabolic risk factors McManus, DD; Rong, J; Huan, T et al. BMC Genomics, DOI://10.1186/s12864-017-3533-9 (2017)
iPSCs and fibroblast subclones from the same fibroblast population contain comparable levels of sequence variations Kwon, EM; Connelly, JP; Hansen, NF et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1616035114 (2017)
Dense genotyping of immune-related loci implicates host responses to microbial exposure in Behçet's disease susceptibility Takeuchi, M; Mizuki, N; Meguro, A et al. Nat. Genet., DOI://10.1038/ng.3786 (2017)
Insights from NMR Spectroscopy into the Conformational Properties of Man-9 and Its Recognition by Two HIV Binding Proteins Shahzad-Ul-Hussan, S; Sastry, M; Lemmin, T et al. Chembiochem, DOI://10.1002/cbic.201600665 (2017)
MNase-Sensitive Complexes in Yeast: Nucleosomes and Non-histone Barriers Chereji, RV; Ocampo, J; Clark, DJ; Mol. Cell, DOI://10.1016/j.molcel.2016.12.009 (2017)
Amyloid β Ion Channels in a Membrane Comprising Brain Total Lipid Extracts Lee, J; Kim, YH; T Arce, F et al. ACS Chem Neurosci, DOI://10.1021/acschemneuro.7b00006 (2017)

Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing Jansen, IE; Ye, H; Heetveld, S et al. Genome Biol., DOI://10.1186/s13059-017-1147-9 (2017)
Secretory Expression and Characterization of Chinese Narcissus GNA-Like Lectin in Pichia pastoris Li, X; Zhang, P; Zhang, N et al. Appl. Biochem. Biotechnol., DOI://10.1007/s12010-017-2408-5 (2017)
Hybrid assembly of the large and highly repetitive genome of Aegilops tauschii, a progenitor of bread wheat, with the MaSuRCA mega-reads algorithm Zimin, AV; Puiu, D; Luo, MC et al. Genome Res., DOI://10.1101/gr.213405.116 (2017)
Hedgehog Signaling Inhibitors Fail to Reduce Merkel Cell Carcinoma Viability Carroll, TM; Williams, JS; Daily, K et al. J. Invest. Dermatol., DOI://10.1016/j.jid.2017.01.008 (2017)
Differential methylation of genes in individuals exposed to maternal diabetes in utero Chen, P; Piaggi, P; Traurig, M et al. Diabetologia, DOI://10.1007/s00125-016-4203-1 (2017)
ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans Lyons, JJ; Liu, Y; Ma, CA et al. J. Exp. Med., DOI://10.1084/jem.20161435 (2017)

Frequent inactivating germline mutations in DNA repair genes in patients with Ewing sarcoma Brohl, AS; Patidar, R; Turner, CE et al. Genet. Med., DOI://10.1038/gim.2016.206 (2017)
Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies Joehanes, R; Zhang, X; Huan, T et al. Genome Biol., DOI://10.1186/s13059-016-1142-6 (2017)
Gleason Score 7 Prostate Cancers Emerge through Branched Evolution of Clonal Gleason Pattern 3 and 4 Sowalsky, AG; Kissick, HT; Gerrin, SJ et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-16-2414 (2017)
Dose coefficients for ICRP reference pediatric phantoms exposed to idealised external gamma fields Chang, LA; Simon, SL; Jorgensen, TJ; Schauer, DA; Lee, C; J Radiol Prot, DOI://10.1088/1361-6498/aa559e (2017)
Actin dynamics and competition for myosin monomer govern the sequential amplification of myosin filaments Beach, JR; Bruun, KS; Shao, L et al. Nat. Cell Biol., DOI://10.1038/ncb3463 (2017)
Functionally-interdependent shape-switching nanoparticles with controllable properties Halman, JR; Satterwhite, E; Roark, B et al. Nucleic Acids Res., DOI://10.1093/nar/gkx008 (2017)

SDHD promoter mutations ablate GABP transcription factor binding in melanoma Zhang, T; Xu, M; Makowski, MM et al. Cancer Res., DOI://10.1158/0008-5472.CAN-16-0919 (2017)
Static and Evolving Norovirus Genotypes: Implications for Epidemiology and Immunity Parra, GI; Squires, RB; Karangwa, CK et al. PLoS Pathog., DOI://10.1371/journal.ppat.1006136 (2017)
Novel genetic loci associated with hippocampal volume Hibar, DP; Adams, HH; Jahanshad, N et al. Nat Commun, DOI://10.1038/ncomms13624 (2017)
Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach Mendelson, MM; Marioni, RE; Joehanes, R et al. PLoS Med., DOI://10.1371/journal.pmed.1002215 (2017)
Quantitative stability of hematopoietic stem and progenitor cell clonal output in rhesus macaques receiving transplants Koelle, SJ; Espinoza, DA; Wu, C et al. Blood, DOI://10.1182/blood-2016-07-728691 (2017)
Designer Drugs 2.0 Huestis, MA; Tyndale, RF; Clin. Pharmacol. Ther., DOI://10.1002/cpt.575 (2017)
Sequence of Reston Virus Isolate AZ-1435, an Ebolavirus Isolate Obtained during the 1989-1990 Reston Virus Epizootic in the United States Cornish, JP; Diaz, L; Ricklefs, SM et al. Genome Announc, DOI://10.1128/genomeA.01448-16 (2017)
An Estimation of Hybrid Quantum Mechanical Molecular Mechanical Polarization Energies for Small Molecules Using Polarizable Force-Field Approaches Huang, J; Mei, Y; König, G et al. J Chem Theory Comput, DOI://10.1021/acs.jctc.6b01125 (2017)
Familial Mutations May Switch Conformational Preferences in α-Synuclein Fibrils Xu, L; Ma, B; Nussinov, R; Thompson, D; ACS Chem Neurosci, DOI://10.1021/acschemneuro.6b00406 (2017)
High fat diet-induced changes of mouse hepatic transcription and enhancer activity can be reversed by subsequent weight loss Siersbæk, M; Varticovski, L; Yang, S et al. Sci Rep, DOI://10.1038/srep40220 (2017)
The primacy of NF1 loss as the driver of tumorigenesis in neurofibromatosis type 1-associated plexiform neurofibromas Pemov, A; Li, H; Patidar, R et al. Oncogene, DOI://10.1038/onc.2016.464 (2017)
Performing Skin Microbiome Research: A Method to the Madness Kong, HH; Andersson, B; Clavel, T et al. J. Invest. Dermatol., DOI://10.1016/j.jid.2016.10.033 (2017)

Characterization of the disassembly and reassembly of the HBV glycoprotein surface antigen, a pliable nanoparticle vaccine platform Gallagher, JR; Torian, U; McCraw, DM; Harris, AK; Virology, DOI://10.1016/j.virol.2016.12.025 (2017)
The Papillomavirus Episteme: a major update to the papillomavirus sequence database Van Doorslaer, K; Li, Z; Xirasagar, S et al. Nucleic Acids Res., DOI://10.1093/nar/gkw879 (2017)
Genetic stability of genome-scale deoptimized RNA virus vaccine candidates under selective pressure Le Nouën, C; McCarty, T; Brown, M et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1619242114 (2017)
Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting Doria-Rose, NA; Altae-Tran, HR; Roark, RS et al. PLoS Pathog., DOI://10.1371/journal.ppat.1006148 (2017)
An insight into the sialome of Hyalomma excavatum Ribeiro, JM; Slovák, M; Francischetti, IM; Ticks Tick Borne Dis, DOI://10.1016/j.ttbdis.2016.08.011 (2017)
Data integration in physiology using Bayes' rule and minimum Bayes' factors: deubiquitylating enzymes in the renal collecting duct Xue, Z; Chen, JX; Zhao, Y; Medvar, B; Knepper, MA; Physiol. Genomics, DOI://10.1152/physiolgenomics.00120.2016 (2017)

Human Neuronal Calcium Sensor-1 Protein Avoids Histidine Residues To Decrease pH Sensitivity Gong, Y; Zhu, Y; Zou, Y; Ma, B; Nussinov, R; Zhang, Q; J Phys Chem B, DOI://10.1021/acs.jpcb.6b11094 (2017)
Computational models of the neural control of breathing Molkov, YI; Rubin, JE; Rybak, IA; Smith, JC; Wiley Interdiscip Rev Syst Biol Med, DOI://10.1002/wsbm.1371 (2017)
Structural studies of influenza virus RNPs by electron microscopy indicate molecular contortions within NP supra-structures Gallagher, JR; Torian, U; McCraw, DM; Harris, AK; J. Struct. Biol., DOI://10.1016/j.jsb.2016.12.007 (2017)
EBI2 overexpression in mice leads to B1 B-cell expansion and chronic lymphocytic leukemia-like B-cell malignancies Niss Arfelt, K; Barington, L; Benned-Jensen, T et al. Blood, DOI://10.1182/blood-2016-02-697185 (2017)
The cell cycle restricts activation-induced cytidine deaminase activity to early G1 Wang, Q; Kieffer-Kwon, KR; Oliveira, TY et al. J. Exp. Med., DOI://10.1084/jem.20161649 (2017)
Neural Markers in Pediatric Bipolar Disorder and Familial Risk for Bipolar Disorder Wiggins, JL; Brotman, MA; Adleman, NE et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2016.10.009 (2017)

The bald and the beautiful: hairlessness in domestic dog breeds Parker, HG; Harris, A; Dreger, DL; Davis, BW; Ostrander, EA; Philos. Trans. R. Soc. Lond., B, Biol. Sci., DOI://10.1098/rstb.2015.0488 (2017)
ADORA1 mutations are not a common cause of Parkinson's disease and dementia with Lewy bodies Blauwendraat, C; Nalls, MA; Federoff, M et al. Mov. Disord., DOI://10.1002/mds.26886 (2017)
Temporal association of ORCA/LRWD1 to late-firing origins during G1 dictates heterochromatin replication and organization Wang, Y; Khan, A; Marks, AB et al. Nucleic Acids Res., DOI://10.1093/nar/gkw1211 (2017)
Acquired somatic mutations in PNH reveal long-term maintenance of adaptive NK cells independent of HSPCs Corat, MA; Schlums, H; Wu, C et al. Blood, DOI://10.1182/blood-2016-08-734285 (2017)
Whole exome sequencing in 75 high-risk families with validation and replication in independent case-control studies identifies TANGO2, OR5H14, and CHAD as new prostate cancer susceptibility genes Karyadi, DM; Geybels, MS; Karlins, E et al. Oncotarget, DOI://10.18632/oncotarget.13646 (2017)
Long-term monitoring of cardiorespiratory patterns in drug-resistant epilepsy Goldenholz, DM; Kuhn, A; Austermuehle, A et al. Epilepsia, DOI://10.1111/epi.13606 (2017)
Assessing variation across 8 established East Asian loci for type 2 diabetes mellitus in American Indians: Suggestive evidence for new sex-specific diabetes signals in GLIS3 and ZFAND3 Muller, YL; Piaggi, P; Chen, P et al. Diabetes Metab. Res. Rev., DOI://10.1002/dmrr.2869 (2017)
Estimating the Heritability of Structural and Functional Brain Connectivity in Families Affected by Attention-Deficit/Hyperactivity Disorder Sudre, G; Choudhuri, S; Szekely, E et al. JAMA Psychiatry, DOI://10.1001/jamapsychiatry.2016.3072 (2017)
Oculocutaneous albinism type 1: link between mutations, tyrosinase conformational stability, and enzymatic activity Dolinska, MB; Kus, NJ; Farney, SK; Wingfield, PT; Brooks, BP; Sergeev, YV; Pigment Cell Melanoma Res, DOI://10.1111/pcmr.12546 (2017)
DLX3-Dependent Regulation of Ion Transporters and Carbonic Anhydrases is Crucial for Enamel Mineralization Duverger, O; Ohara, T; Bible, PW; Zah, A; Morasso, MI; J. Bone Miner. Res., DOI://10.1002/jbmr.3022 (2017)
Untangling the relatedness among correlations, Part II: Inter-subject correlation group analysis through linear mixed-effects modeling Chen, G; Taylor, PA; Shin, YW; Reynolds, RC; Cox, RW; Neuroimage, DOI://10.1016/j.neuroimage.2016.08.029 (2017)
Topographical and physiological differences of the skin mycobiome in health and disease Jo, JH; Kennedy, EA; Kong, HH; Virulence, DOI://10.1080/21505594.2016.1249093 (2017)
Empirically derived patterns of psychiatric symptoms in youth: A latent profile analysis Kircanski, K; Zhang, S; Stringaris, A et al. J Affect Disord, DOI://10.1016/j.jad.2016.09.016 (2017)
Absolute binding free energy calculations of CBClip host-guest systems in the SAMPL5 blind challenge Lee, J; Tofoleanu, F; Pickard, FC et al. J. Comput. Aided Mol. Des., DOI://10.1007/s10822-016-9968-2 (2017)
Immobilized MutS-Mediated Error Removal of Microchip-Synthesized DNA Wan, W; Wang, D; Gao, X; Hong, J; Methods Mol. Biol., DOI://10.1007/978-1-4939-6343-0_17 (2017)
Perfluoroalkyl Chemicals, Menstrual Cycle Length, and Fecundity: Findings from a Prospective Pregnancy Study Lum, KJ; Sundaram, R; Barr, DB; Louis, TA; Buck Louis, GM; Epidemiology, DOI://10.1097/EDE.0000000000000552 (2017)
Anxiety Patients Show Reduced Working Memory Related dlPFC Activation During Safety and Threat Balderston, NL; Vytal, KE; O'Connell, K et al. Depress Anxiety, DOI://10.1002/da.22518 (2017)

2016 (409 papers)

Can dielectric spheres accurately model atomic-scale interactions Obolensky, OI; Doerr, TP; Ogurtsov, AY; Yu, YK; Europhys Lett, DOI://10.1209/0295-5075/116/24003 (2016)

Direct Regulation of Alternative Splicing by SMAD3 through PCBP1 Is Essential to the Tumor-Promoting Role of TGF-β Tripathi, V; Sixt, KM; Gao, S et al. Mol. Cell, DOI://10.1016/j.molcel.2016.09.013 (2016)
Functional connectivity during masked and unmasked face emotion processing in bipolar disorder Tseng, WL; Thomas, LA; Harkins, E et al. Psychiatry Res Neuroimaging, DOI://10.1016/j.pscychresns.2016.10.006 (2016)
Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase Puppala, AK; French, RL; Matthies, D; Baxa, U; Subramaniam, S; Simonović, M; Sci Rep, DOI://10.1038/srep32563 (2016)
Ionic immune suppression within the tumour microenvironment limits T cell effector function Eil, R; Vodnala, SK; Clever, D et al. Nature, DOI://10.1038/nature19364 (2016)
Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche Clever, D; Roychoudhuri, R; Constantinides, MG et al. Cell, DOI://10.1016/j.cell.2016.07.032 (2016)
The transcription factor BACH2 promotes tumor immunosuppression Roychoudhuri, R; Eil, RL; Clever, D et al. J. Clin. Invest., DOI://10.1172/JCI82884 (2016)

BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers Roychoudhuri, R; Clever, D; Li, P et al. Nat. Immunol., DOI://10.1038/ni.3441 (2016)
Memory T cell-driven differentiation of naive cells impairs adoptive immunotherapy Klebanoff, CA; Scott, CD; Leonardi, AJ et al. J. Clin. Invest., DOI://10.1172/JCI81217 (2016)
Human-Mouse Chimeras with Normal Expression and Function Reveal That Major Domain Swapping Is Tolerated by P-Glycoprotein (ABCB1) Pluchino, KM; Hall, MD; Moen, JK et al. Biochemistry, DOI://10.1021/acs.biochem.5b01064 (2016)
Drugging Ras GTPase: a comprehensive mechanistic and signaling structural view Lu, S; Jang, H; Gu, S; Zhang, J; Nussinov, R; Chem Soc Rev, DOI://10.1039/c5cs00911a (2016)
Pioneer factors and ATP-dependent chromatin remodeling factors interact dynamically: A new perspective: Multiple transcription factors can effect chromatin pioneer functions through dynamic interactions with ATP-dependent chromatin remodeling factors Swinstead, EE; Paakinaho, V; Presman, DM; Hager, GL; Bioessays, DOI://10.1002/bies.201600137 (2016)
Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant Li, J; Woods, SL; Healey, S et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2016.03.001 (2016)

Deep genome sequencing and variation analysis of 13 inbred mouse strains defines candidate phenotypic alleles, private variation and homozygous truncating mutations Doran, AG; Wong, K; Flint, J; Adams, DJ; Hunter, KW; Keane, TM; Genome Biol., DOI://10.1186/s13059-016-1024-y (2016)
A Small Number of Residues Can Determine if Linker Histones Are Bound On or Off Dyad in the Chromatosome Zhou, BR; Feng, H; Ghirlando, R; Li, S; Schwieters, CD; Bai, Y; J. Mol. Biol., DOI://10.1016/j.jmb.2016.08.016 (2016)
Comparing Brain Morphometry Across Multiple Childhood Psychiatric Disorders Gold, AL; Brotman, MA; Adleman, NE et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2016.08.008 (2016)
Toward elucidating the heat activation mechanism of the TRPV1 channel gating by molecular dynamics simulation Wen, H; Qin, F; Zheng, W; Proteins, DOI://10.1002/prot.25177 (2016)
Blind prediction of distribution in the SAMPL5 challenge with QM based protomer and pK a corrections Pickard, FC; König, G; Tofoleanu, F et al. J. Comput. Aided Mol. Des., DOI://10.1007/s10822-016-9955-7 (2016)
Identification of therapeutic targets applicable to clinical strategies in ovarian cancer Kim, MK; Caplen, N; Chakka, S et al. BMC Cancer, DOI://10.1186/s12885-016-2675-5 (2016)
Childhood peer network characteristics: genetic influences and links with early mental health trajectories Szekely, E; Pappa, I; Wilson, JD et al. J Child Psychol Psychiatry, DOI://10.1111/jcpp.12493 (2016)
Outcome of the First wwPDB/CCDC/D3R Ligand Validation Workshop Adams, PD; Aertgeerts, K; Bauer, C et al. Structure, DOI://10.1016/j.str.2016.02.017 (2016)
Partition coefficients for the SAMPL5 challenge using transfer free energies Jones, MR; Brooks, BR; Wilson, AK; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-016-9964-6 (2016)
Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III Esser, L; Zhou, F; Zhou, Y et al. J. Biol. Chem., DOI://10.1074/jbc.M116.744391 (2016)
An Open Pilot Study of Training Hostile Interpretation Bias to Treat Disruptive Mood Dysregulation Disorder Stoddard, J; Sharif-Askary, B; Harkins, EA et al. J Child Adolesc Psychopharmacol, DOI://10.1089/cap.2015.0100 (2016)
Estimation of FST and the Impact of de novo Mutation Shriner, D; Chen, G; Adeyemo, A; Rotimi, CN; Hum. Hered., DOI://10.1159/000477782 (2016)

Neuroendocrine Tumor of the Pancreas as a Manifestation of Cowden Syndrome: A Case Report Neychev, V; Sadowski, SM; Zhu, J et al. J. Clin. Endocrinol. Metab., DOI://10.1210/jc.2015-3684 (2016)
Light induced structural changes of the photoprotein mnemiopsin: Characterization and contribution in photoinactivation Pashandi, Z; Molakarimi, M; Sajedi, RH; Taghdir, M; Naderi-Manesh, H; J. Photochem. Photobiol. B, Biol., DOI://10.1016/j.jphotobiol.2016.10.018 (2016)
Robust spike sorting of retinal ganglion cells tuned to spot stimuli Ghahari, A; Badea, TC; Conf Proc IEEE Eng Med Biol Soc, DOI://10.1109/EMBC.2016.7591054 (2016)
Assessing the reproducibility of exome copy number variations predictions Hong, CS; Singh, LN; Mullikin, JC; Biesecker, LG; Genome Med, DOI://10.1186/s13073-016-0336-6 (2016)
Computation of Hydration Free Energies Using the Multiple Environment Single System Quantum Mechanical/Molecular Mechanical Method König, G; Mei, Y; Pickard, FC et al. J Chem Theory Comput, DOI://10.1021/acs.jctc.5b00874 (2016)
Whole Genome Sequencing of Newly Established Pancreatic Cancer Lines Identifies Novel Somatic Mutation (c.2587G>A) in Axon Guidance Receptor Plexin A1 as Enhancer of Proliferation and Invasion Sorber, R; Teper, Y; Abisoye-Ogunniyan, A et al. PLoS ONE, DOI://10.1371/journal.pone.0149833 (2016)

Identifying Host Genetic Variants Associated with Microbiome Composition by Testing Multiple Beta Diversity Matrices Hua, X; Goedert, JJ; Landi, MT; Shi, J; Hum. Hered., DOI://10.1159/000448733 (2016)
Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data Shi, J; Park, JH; Duan, J et al. PLoS Genet., DOI://10.1371/journal.pgen.1006493 (2016)
Block network mapping approach to quantitative trait locus analysis Shreif, ZZ; Gatti, DM; Periwal, V; BMC Bioinformatics, DOI://10.1186/s12859-016-1351-8 (2016)
Lineage-Specific and Non-specific Cytokine-Sensing Genes Respond Differentially to the Master Regulator STAT5 Zeng, X; Willi, M; Shin, HY; Hennighausen, L; Wang, C; Cell Rep, DOI://10.1016/j.celrep.2016.11.079 (2016)
Meta-analysis of quantitative pleiotropic traits for next-generation sequencing with multivariate functional linear models Chiu, CY; Jung, J; Chen, W et al. Eur. J. Hum. Genet., DOI://10.1038/ejhg.2016.170 (2016)
Towards understanding the structural basis of partial agonism at the dopamine D3 receptor Michino, M; Boateng, CA; Donthamsetti, P et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.6b01148 (2016)
Comparison of parametric and machine methods for variable selection in simulated Genetic Analysis Workshop 19 data Holzinger, ER; Szymczak, S; Malley, J et al. BMC Proc, DOI://10.1186/s12919-016-0021-1 (2016)
From 20th Century Metabolic Wall Charts to 21st Century Systems Biology: Database of Mammalian Metabolic Enzymes Corcoran, CC; Grady, CR; Pisitkun, T; Parulekar, J; Knepper, MA; Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00601.2016 (2016)
Lipid and Peptide Diffusion in Bilayers: The Saffman-Delbrück Model and Periodic Boundary Conditions Venable, RM; Ingólfsson, HI; Lerner, MG et al. J Phys Chem B, DOI://10.1021/acs.jpcb.6b09111 (2016)
DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases Ligthart, S; Marzi, C; Aslibekyan, S et al. Genome Biol., DOI://10.1186/s13059-016-1119-5 (2016)
Structure-Based Scaffold Repurposing for G Protein-Coupled Receptors: Transformation of Adenosine Derivatives into 5HT2B/5HT2C Serotonin Receptor Antagonists Tosh, DK; Ciancetta, A; Warnick, E; Crane, S; Gao, ZG; Jacobson, KA; J. Med. Chem., DOI://10.1021/acs.jmedchem.6b01183 (2016)
Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications Ombrello, MJ; Arthur, VL; Remmers, EF et al. Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2016-210324 (2016)
Mechanisms of Evolution in High-Consequence Drug Resistance Plasmids He, S; Chandler, M; Varani, AM; Hickman, AB; Dekker, JP; Dyda, F; MBio, DOI://10.1128/mBio.01987-16 (2016)
Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study Shi, J; Hua, X; Zhu, B et al. PLoS Med., DOI://10.1371/journal.pmed.1002162 (2016)
Mapping Complex Traits in a Diversity Outbred F1 Mouse Population Identifies Germline Modifiers of Metastasis in Human Prostate Cancer Winter, JM; Gildea, DE; Andreas, JP et al. Cell Syst, DOI://10.1016/j.cels.2016.10.018 (2016)
A comparison study of multivariate fixed models and Gene Association with Multiple Traits (GAMuT) for next-generation sequencing Chiu, CY; Jung, J; Wang, Y et al. Genet. Epidemiol., DOI://10.1002/gepi.22014 (2016)
Sparse multidimensional iterative lineshape-enhanced (SMILE) reconstruction of both non-uniformly sampled and conventional NMR data Ying, J; Delaglio, F; Torchia, DA; Bax, A; J. Biomol. NMR, DOI://10.1007/s10858-016-0072-7 (2016)
Robust skull stripping using multiple MR image contrasts insensitive to pathology Roy, S; Butman, JA; Pham, DL; Neuroimage, DOI://10.1016/j.neuroimage.2016.11.017 (2016)

Association of Irritability and Anxiety With the Neural Mechanisms of Implicit Face Emotion Processing in Youths With Psychopathology Stoddard, J; Tseng, WL; Kim, P et al. JAMA Psychiatry, DOI://10.1001/jamapsychiatry.2016.3282 (2016)
Early generated B1 B cells with restricted BCRs become chronic lymphocytic leukemia with continued c-Myc and low Bmf expression Hayakawa, K; Formica, AM; Brill-Dashoff, J et al. J. Exp. Med., DOI://10.1084/jem.20160712 (2016)
Allosteric control of antibody-prion recognition through oxidation of a disulfide bond between the CH and CL chains Zhao, J; Nussinov, R; Ma, B; Protein Eng. Des. Sel., DOI://10.1093/protein/gzw065 (2016)
High-level expression of improved thermo-stable alkaline xylanase variant in Pichia Pastoris through codon optimization, multiple gene insertion and high-density fermentation Lu, Y; Fang, C; Wang, Q; Zhou, Y; Zhang, G; Ma, Y; Sci Rep, DOI://10.1038/srep37869 (2016)
Molecular Diagnosis of Inherited Retinal Diseases in Indigenous African Populations by Whole-Exome Sequencing Roberts, L; Ratnapriya, R; du Plessis, M; Chaitankar, V; Ramesar, RS; Swaroop, A; Invest. Ophthalmol. Vis. Sci., DOI://10.1167/iovs.16-19785 (2016)
Stage-Specific Transcriptome and Proteome Analyses of the Filarial Parasite Onchocerca volvulus and Its Wolbachia Endosymbiont Bennuru, S; Cotton, JA; Ribeiro, JM et al. MBio, DOI://10.1128/mBio.02028-16 (2016)

NRL-Regulated Transcriptome Dynamics of Developing Rod Photoreceptors Kim, JW; Yang, HJ; Brooks, MJ et al. Cell Rep, DOI://10.1016/j.celrep.2016.10.074 (2016)
Whole-genome sequence, SNP chips and pedigree structure: building demographic profiles in domestic dog breeds to optimize genetic-trait mapping Dreger, DL; Rimbault, M; Davis, BW; Bhatnagar, A; Parker, HG; Ostrander, EA; Dis Model Mech, DOI://10.1242/dmm.027037 (2016)
Integrative network analysis reveals molecular mechanisms of blood pressure regulation Tianxiao Huan, Qingying Meng et al. Mol Syst Biol., doi: 10.15252/msb.20145399 (2016)
C. elegans DAF-2 as a Model for Human Insulin Receptoropathies David A. Bulger, Tetsunari Fukushige, Sijung Yun, Robert K. Semple, John A. Hanover, and Michael W. Krause Genes|Genomes|Genetics, doi:10.1534/g3.116.03718 (2016)
Generation and differentiation of induced pluripotent stem cells reveal ankylosing spondylitis risk gene expression in bone progenitors Gerlinde Layh-Schmitt, Shajia Lum Fatemehm Navid, Stephen R. Brooks, Emily Lazowick, Kathryn M. Davis, Cristina Montagna, Massimo Gadina, Robert A. Colbert Clinical Rheumatology, doi:10.1007/s10067-016-3469-5 (2016)
The genome of Onchocerca volvulus, agent of river blindness Cotton, JA; Bennuru, S; Grote, A et al. Nat Microbiol, DOI://10.1038/nmicrobiol.2016.216 (2016)

Two Na+ Sites Control Conformational Change in a Neurotransmitter Transporter Homolog Sotiria Tavoulari, Eleonora Margheritis, Anu Nagarajan, David C. DeWitt, Yuan -Wei Zhang, Edwin Rosado, Silvia Ravera, Elizabeth Rhoades, Lucy R. Forrest and Gary Rudnick J Biol Chem. , doi: 10.1074/jbc.M115.692012. (2016)
Techniques for blood volume fMRI with VASO: From low-resolution mapping towards sub-millimeter layer-dependent applications Huber, L; Ivanov, D; Handwerker, DA et al. Neuroimage, DOI://10.1016/j.neuroimage.2016.11.039 (2016)
Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity Esser, L; Zhou, F; Pluchino, KM et al. J. Biol. Chem., DOI://10.1074/jbc.M116.755884 (2016)
Physiological basis of vascular autocalibration (VasA): Comparison to hypercapnia calibration methods Kazan, SM; Huber, L; Flandin, G; Ivanov, D; Bandettini, P; Weiskopf, N; Magn Reson Med, DOI://10.1002/mrm.26494 (2016)
Serine/Threonine Phosphatases and Aquaporin-2 Regulation in Renal Collecting Duct Sophia LeMaire, Viswanathan Raghuram, Cameron R. Grady, Christina M. Pickering, Chung-Lin Chou, Ezigbobiara N Umejiego, Mark A. Knepper Am. J. Physiol. - Renal Physiol. , DOI: 10.1152/ajprenal.00455.2016 (2016)
Identification of a novel lipid binding motif in apolipoprotein B by the analysis of hydrophobic cluster domains Scott M. Gordon, Mohsen Pourmousa, Maureen Sampson, Denis Sviridov, Rafique Islam, B. Scott Perrin Jr., Georgina Kemeh, Richard W. Pastor, Alan T. Remaley Biochimica et Biophysica Acta - Membranes, doi://10.1016/j.bbamem.2016.10.019 (2016)

Convergence and Sampling in Determining Free Energy Landscapes for Membrane Protein Association Jan Domanski, George Hedger, Robert B. Best, Phillip James Stansfeld, and Mark S. P. Sansom J. Phys. Chem. B, doi://10.1021/acs.jpcb.6b08445 (2016)
Transcriptome Profiling of NIH3T3 Cell Lines Expressing Opsin and the P23H Opsin Mutant Identifies Candidate Drugs for the Treatment of Retinitis Pigmentosa Yuanyuan Chen, Matthew J. Brooks, Linn Gieser, Anand Swaroop, Krzysztof Palczewski Pharmacological Research, doi://10.1016/j.phrs.2016.10.031 (2016)
RNA-seq analyses of the midgut from blood- and serum-fed Ixodes ricinus ticks Perner, J; Provazník, J; Schrenková, J; Urbanová, V; Ribeiro, JM; Kopáček, P; Sci Rep, DOI://10.1038/srep36695 (2016)
Transgenic mouse model of IgM(+) lymphoproliferative disease mimicking Waldenström macroglobulinemia Tompkins, VS; Sompallae, R; Rosean, TR et al. Blood Cancer J, DOI://10.1038/bcj.2016.95 (2016)
Mechanism of O2 diffusion and reduction in FeFe hydrogenases Adam Kubas, Christophe Orain et al. Nature Chemistry, doi:10.1038/nchem.2592 (2016)
Variance Decomposition for Single-Subject task-based fMRI activity estimates across many sessions Javier Gonzalez-Castillo, Gang Chen, Thomas E. Nichols, Peter A. Bandettini NeuroImage, doi://10.1016/j.neuroimage.2016.10.024 (2016)

Explicit Incorporation of Hard and Soft Protein-Protein Interactions Into Models for Crowding Effects in Binary and Ternary Protein Mixtures I. Comparison of Approximate Analytical Solutions With Numerical Simulation Travis Hoppe, and Allen P. Minton J. Phys. Chem. B, DOI: 10.1021/acs.jpcb.6b07736 (2016)
Resting State Connectivity of the Human Habenula at Ultra-High Field Salvatore Torrisi, Camilla L. Nord, Nicholas L. Balderston, Jonathan P. Roiser, Christian Grillon, Monique Ernst NeuroImage, 10.1016/j.neuroimage.2016.10.034 (2016)
The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts Saini, N; Roberts, SA; Klimczak, LJ et al. PLoS Genet., DOI://10.1371/journal.pgen.1006385 (2016)
Roles of H3K27me2 and H3K27me3 Examined during Fate Specification of Embryonic Stem Cells Juan, AH; Wang, S; Ko, KD et al. Cell Rep, DOI://10.1016/j.celrep.2016.09.087 (2016)
Deriving frequency-dependent spatial patterns in MEG-derived resting state sensorimotor network: A novel multiband ICA technique Nugent, A. C., Luber, B., Carver, F. W., Robinson, S. E., Coppola, R. and Zarate, C. A. Hum. Brain Mapp., doi:10.1002/hbm.23417 (2016)
Additional Rare Variant Analysis in Parkinson's Disease Cases with and Without Known Pathogenic Mutations: Evidence for Oligogenic Inheritance Steven J. Lubbe, Valentina Escott-Price et al. Human Molecular Genetics, doi://10.1093/hmg/ddw348 (2016)

Longitudinal imaging in C9orf72 mutation carriers: Relationship to phenotype Mary Kay Floeter, Devin Bageac, Laura E. Danielian, Laura E. Braun, Bryan J. Traynor, , Justin Kwan NeuroImage: Clinical, doi://10.1016/j.nicl.2016.10.014 (2016)
Racial differences in microRNA and gene expression in hypertensive women Dluzen, DF; Noren Hooten, N; Zhang, Y et al. Sci Rep, DOI://10.1038/srep35815 (2016)
Structural Characterization of Arginine Fingers: Identification of an Arginine Finger for the Pyrophosphatase dUTPases Gergely N Nagy, Reynier Suardiaz, Anna Lopata, Oliver Ozohanics, Karoly Vekey, Bernard R. Brooks, Ibolya Leveles, Judit Toth, Beata G Vertessy, and Edina Rost JACS, doi://10.1021/jacs.6b09012 (2016)
Molecular lock regulates binding of glycine to a primitive NMDA receptor Alvin Yu, Robert Alberstein, Alecia Thomas, Austin Zimmet, Richard Grey, Mark L. Mayer, and Albert Y. Lau PNAS, doi: 10.1073/pnas.1607010113 (2016)
Sources and implications of whole-brain fMRI signals in humans Jonathan D Power, Mark Plitt, Timothy O Laumann, Alex Martin Neuroimage, doi://10.1016/j.neuroimage.2016.09.038 (2016)
Diagnosis of Parkinson's disease on the basis of clinical-genetic classification: a population-based modelling study Mike A. Nalls, Cory Y. McLean et al. Lancet Neurol., doi: 10.1016/S1474-4422(15)00178-7 (2016)

Microenvironmental Gene Expression Plasticity Among Individual Drosophila melanogaster Lin, Y; Chen, ZX; Oliver, B; Harbison, ST; G3 (Bethesda), DOI://10.1534/g3.116.035444 (2016)
A RUNX2-Mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells Shin, MH; He, Y; Marrogi, E et al. PLoS Genet., DOI://10.1371/journal.pgen.1005884 (2016)
Sp5 and Sp8 recruit β-catenin and Tcf1-Lef1 to select enhancers to activate Wnt target gene transcription Kennedy, MW; Chalamalasetty, RB; Thomas, S; Garriock, RJ; Jailwala, P; Yamaguchi, TP; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1519994113 (2016)
Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number Lyons, JJ; Yu, X; Hughes, JD et al. Nat. Genet., DOI://10.1038/ng.3696 (2016)
SARAH Domain-Mediated MST2-RASSF Dimeric Interactions Goar Sànchez-Sanz , Bartomiej Tywoniuk , David Matallanas, David Romano, Lan K. Nguyen, Boris N. Kholodenko, Edina Rosta , Walter Kolch , Nicolae-Viorel Buchete PLoS Computational Biology, doi://10.1371/journal.pcbi.1005051 (2016)
Systems-level analysis reveals selective regulation of Aqp2 gene expression by vasopressin Sandoval, PC; Claxton, JS; Lee, JW; Saeed, F; Hoffert, JD; Knepper, MA; Sci Rep, DOI://10.1038/srep34863 (2016)
Evaluation of KIR3DL1/KIR3DS1 polymorphism in Behçet's disease Erer, B; Takeuchi, M; Ustek, D et al. Genes Immun., DOI://10.1038/gene.2016.36 (2016)
Rapid development of a DNA vaccine for Zika virus Dowd, KA; Ko, SY; Morabito, KM et al. Science, DOI://10.1126/science.aai9137 (2016)
A Modified P1 Moiety Enhances in vitro Antiviral Activity against Various Multi-Drug-Resistant HIV-1 Variants and in vitro CNS Penetration Properties of a Novel Nonpeptidic Protease Inhibitor, GRL-10413 Masayuki Amano, Pedro Miguel Salcedo-Gomez, Rui Zhao, Ravikiran S. Yedidi, Debananda Das, Haydar Bulut, Nicole S. Delino, Sheri Venkata Reddy, Arun K. Ghosh and Hiroaki Mitsuya Antimicrobial Agents and Chemotherapy, doi: 10.1128/AAC.01428-16 (2016)
Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations BH Chen, M-F Hivert et al. Diabetes, doi://10.2337/db16-0470 (2016)
On the Selective Packaging of Genomic RNA by HIV-1 Mauricio Comas-Garcia, Sean R. Davis and Alan Rein Viruses, doi://10.3390/v8090246 (2016)
Behavioral and Neural Sustained Attention Deficits in Bipolar Disorder and Familial Risk for Bipolar Disorder David Pagliaccio, Jillian Lee Wiggins, et al. Biological Psychiatry, doi://10.1016/j.biopsych.2016.09.006 (2016)

Mutations of SGO2 and CLDN14 collectively cause coincidental Perrault syndrome R Faridi, AR Rehman et al. Clinical Genetics, DOI: 10.1111/cge.12867 (2016)
CYP2A6 genetic variation alters striatal-cingulate circuits, network hubs, and executive processing in smokers Sufang Li, Yihong Yang, Ewa Hoffmann, Rachel F. Tyndale, Elliot A. Stein Biological Psychiatry, doi://10.1016/j.biopsych.2016.09.013 (2016)
Absolute binding free energies for octa-acids and guests in SAMPL5 Florentina Tofoleanu, Juyong Lee, Frank C. Pickard IV, Gerhard Kzönig, Jing Huang, Minkyung Baek, Chaok Seok, Bernard R. Brooks J. Computer-Aided Molecular Design, DOI: 10.1007/s10822-016-9965-5 (2016)
Introduction, evolution, and dissemination of influenza A viruses in exhibition swine, USA, 2009-2013 Martha I. Nelson, Karla M. Stucker, et al. J. Virology, doi: 10.1128/JVI.01457-16 (2016)
Novel genetic loci underlying human intracranial volume identified through genome-wide association Adams, HH; Hibar, DP; Chouraki, V et al. Nat. Neurosci., DOI://10.1038/nn.4398 (2016)
Differential cytokine sensitivities of STAT5-dependent enhancers rely on Stat5 autoregulation Willi, M; Yoo, KH; Wang, C; Trajanoski, Z; Hennighausen, L; Nucleic Acids Res., DOI://10.1093/nar/gkw844 (2016)
DNA methylation-based measures of biological age: meta-analysis predicting time to death Chen, BH; Marioni, RE; Colicino, E et al. Aging (Albany NY), DOI://10.18632/aging.101020 (2016)
Characterization and phosphoproteomic analysis of a human immortalized podocyte model of Fabry disease generated using CRISPR/Cas9 technology Pereira, EM; Labilloy, A; Eshbach, ML et al. Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00283.2016 (2016)
Alternative Isoform Analysis of Ttc8 Expression in the Rat Pineal Gland Using a Multi-Platform Sequencing Approach Reveals Neural Regulation Hartley, SW; Mullikin, JC; Klein, DC; Park, M; , ; Coon, SL; PLoS ONE, DOI://10.1371/journal.pone.0163590 (2016)
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals Ehret, GB; Ferreira, T; Chasman, DI et al. Nat. Genet., DOI://10.1038/ng.3667 (2016)
Integrative Transcriptome Analyses of Metabolic Responses in Mice Define Pivotal LncRNA Metabolic Regulators Yang, L; Li, P; Yang, W et al. Cell Metab., DOI://10.1016/j.cmet.2016.08.019 (2016)
REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants Ioannidis, NM; Rothstein, JH; Pejaver, V et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2016.08.016 (2016)

Oncogenic Mutations Differentially Affect Bax Monomer, Dimer, and Oligomeric Pore Formation in the Membrane Mingzhen Zhang, Jie Zheng, Ruth Nussinov, Buyong Ma Scientific Reports, 10.1038/srep33340 (2016)
Association of Superoxide Dismutase 2 (SOD2) Genotype with Gray Matter Volume Shrinkage in Chronic Alcohol Users: Replication and Further Evaluation of an Addiction Gene Panel Gitik M, Srivastava V, Hodgkinson CA, Shen PH, Goldman D, Meyerhoff DJ Int. J. Neuropsychopharmacol., DOI://10.1093/ijnp/pyw033 (2016)
Daily physical activity patterns from hip- and wrist-worn accelerometers Shiroma, EJ; Schepps, MA; Harezlak, J et al. Physiol Meas, DOI://10.1088/0967-3334/37/10/1852 (2016)
DNA Transposition at Work Hickman, AB; Dyda, F; Chem. Rev., DOI://10.1021/acs.chemrev.6b00003 (2016)
Expression, purification and identification of a thermolysin-like protease, neutral protease I, from Aspergillus oryzae with the Pichia pastoris expression system Ma, X; Liu, Y; Li, Q et al. Protein Expr. Purif., DOI://10.1016/j.pep.2016.08.008 (2016)
The African diaspora: history, adaptation and health Rotimi CN, Tekola-Ayele F, Baker JL, Shriner D Curr. Opin. Genet. Dev., DOI://10.1016/j.gde.2016.08.005 (2016)
3D-printed head models for navigated non-invasive brain stimulation Dayan, E; Thompson, RM; Buch, ER; Cohen, LG; Clin Neurophysiol, DOI://10.1016/j.clinph.2016.08.011 (2016)
Distinct fMRI Responses to Self-Induced versus Stimulus Motion during Free Viewing in the Macaque Russ, BE; Kaneko, T; Saleem, KS; Berman, RA; Leopold, DA; J. Neurosci., DOI://10.1523/JNEUROSCI.1152-16.2016 (2016)
Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder Hou, L; Bergen, SE; Akula, N et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddw181 (2016)
A genome-wide association study in multiple system atrophy Sailer, A; Scholz, SW; Nalls, MA et al. Neurology, DOI://10.1212/WNL.0000000000003221 (2016)
Diverse Human Skin Fungal Communities in Children Converge in Adulthood Jo, JH; Deming, C; Kennedy, EA et al. J. Invest. Dermatol., DOI://10.1016/j.jid.2016.05.130 (2016)
An efficient protocol for obtaining accurate hydration free energies using quantum chemistry and reweighting from molecular dynamics simulations Frank C. Pickard, Gerhard Koenig, Andrew C. Simmonett, Yihan Shao, Bernard R. Brooks Bioorganic & Medicinal Chemistry, doi://10.1016/j.bmc.2016.08.031 (2016)

Skin microbiome before development of atopic dermatitis: Early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year s: Kennedy EA, Connolly J, O'B Hourihane J, Fallon PG, McLean WI, Murray D, Jo J-H, Segre JA, Kong HH, Irvine AD J. Allergy and Clinical Immunology , doi: 10.1016/j.jaci.2016.07.029 (2016)
Effects of Gene Dose, Chromatin, and Network Topology on Expression in Drosophila melanogaster Hangnoh Lee, Dong-Yeon Cho, Cale Whitworth, Robert Eisman, Melissa Phelps, John Roote, Thomas Kaufman, Kevin Cook, Steven Russell, Teresa Przytycka, Brian Oliver PLoS Genetics, doi://10.1371/journal.pgen.1006295 (2016)
A Model for Transposition of the Colistin Resistance Gene mcr-1 by ISApl1 Snesrud, E; He, S; Chandler, M et al. Antimicrob. Agents Chemother., DOI://10.1128/AAC.01457-16 (2016)
Transferability of genome-wide associated loci for asthma in African Americans Faruque, MU; Chen, G; Doumatey, AP et al. J Asthma, DOI://10.1080/02770903.2016.1188941 (2016)
Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease Zhou, Q; Yu, X; Demirkaya, E et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1612594113 (2016)
GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium Matteini, AM; Tanaka, T; Karasik, D et al. Aging Cell, DOI://10.1111/acel.12468 (2016)

Quantifying antiepileptic drug effects using intrinsic excitability measures Christian Meisel, Dietmar Plenz, Andreas Schulze-Bonhage, Heinz Reichmann Epilepsia, DOI: 10.1111/epi.13517 (2016)
Genetic causes of moderate to severe hearing loss point to modifiers S. Naz, A. Imtiaz et al. Clinical Genetics, DOI: 10.1111/cge.12856 (2016)
Bi-allelic Truncating Mutations in CEP78, Encoding Centrosomal Protein 78, Cause Cone-Rod Degeneration with Sensorineural Hearing Loss Prasanthi Namburi, Rinki Ratnapriya et al. Am. J. Hum. Genet., doi://10.1016/j.ajhg.2016.07.010 (2016)
Structural basis of kainate subtype glutamate receptor desensitization Joel R. Meyerson, Sagar Chittori, Alan Merk, Prashant Rao, Tae Hee Han, Mihaela Serpe, Mark L. Mayer & Sriram Subramaniam Nature, doi:10.1038/nature19352 (2016)
Probing the Action of Chemical Denaturant on an Intrinsically Disordered Protein by Simulation and Experiment Wenwei Zheng, Alessandro Borgia, Karin Buholzer, Alexander Grishaev, Benjamin Schuler, and Robert B. Best JACS, DOI: 10.1021/jacs.6b05443 (2016)
Consistent View of Polypeptide Chain Expansion in Chemical Denaturants from Multiple Experimental Methods A Borgia, W Zheng, et al. JACS, DOI: 10.1021/jacs.6b05917 (2016)
HMGN proteins modulate chromatin regulatory sites and gene expression during activation of naïve B cells Zhang, S; Zhu, I; Deng, T et al. Nucleic Acids Res., DOI://10.1093/nar/gkw323 (2016)
Analysis of Ly49 gene transcripts in mature NK cells supports a role for the Pro1 element in gene activation, not gene expression McCullen MV, Li H, Cam M, Sen SK, McVicar DW, Anderson SK Genes Immun., DOI://10.1038/gene.2016.31 (2016)
Calculating distribution coefficients based on multi-scale free energy simulations: an evaluation of MM and QM/MM explicit solvent simulations of water-cyclohexane transfer in the SAMPL5 challenge König, G; Pickard, FC; Huang, J et al. J. Comput. Aided Mol. Des., DOI://10.1007/s10822-016-9936-x (2016)
Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans Evans, DS; Avery, CL; Nalls, MA et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddw284 (2016)
Altered Human Memory Modification in the Presence of Normal Consolidation Censor N, Buch ER, Nader K, Cohen LG Cereb. Cortex, DOI://10.1093/cercor/bhv180 (2016)
Three-Dimensional Digital Template Atlas of the Macaque Brain Reveley, C; Gruslys, A; Ye, FQ et al. Cereb. Cortex, DOI://10.1093/cercor/bhw248 (2016)

Pleiotropic Analysis of Lung Cancer and Blood Triglycerides Zuber, V; Marconett, CN; Shi, J et al. J. Natl. Cancer Inst., DOI://10.1093/jnci/djw167 (2016)
Early-Childhood Social Reticence Predicts Brain Function in Preadolescent Youths During Distinct Forms of Peer Evaluation Jarcho JM, Davis MM, Shechner T, Degnan KA, Henderson HA, Stoddard J, Fox NA, Leibenluft E, Pine DS, Nelson EE Psychol Sci., doi: 10.1177/0956797616638319 (2016)
Global diversity in the TAS2R38 bitter taste receptor: revisiting a classic evolutionary PROPosal Risso DS, Mezzavilla M et al. Sci Rep., doi: 10.1038/srep25506 (2016)
A Deep Insight into the Sialome of Male and Female Aedes aegypti Mosquitoes Ribeiro JM, Martin-Martin I, Arcà B, Calvo E PLoS One., doi: 10.1371/journal.pone.0151400 (2016)
Noise Estimation and Reduction in Multispectral Magnetic Resonance Images Bouhrara M, Bonny JM, Ashinsky B, Maring M, Spencer R IEEE Trans Med Imaging, DOI://10.1109/TMI.2016.2601243 (2016)
Amygdala response to explicit sad face stimuli at baseline predicts antidepressant treatment response to scopolamine in major depressive disorder Szczepanik, J; Nugent, AC; Drevets, WC; Khanna, A; Zarate, CA; Furey, ML; Psychiatry Res, DOI://10.1016/j.pscychresns.2016.06.005 (2016)

Structure-Based Screening of Uncharted Chemical Space for Atypical Adenosine Receptor Agonists Rodríguez, D; Chakraborty, S; Warnick, E et al. ACS Chem. Biol., DOI://10.1021/acschembio.6b00357 (2016)
Internal Proteins of the Procapsid and Mature Capsids of Herpes Simplex Virus 1 Mapped by Bubblegram Imaging Wu W, Newcomb WW, Cheng N, Aksyuk A, Winkler DC, Steven AC J Virol. , doi: 10.1128/JVI.03224-15 (2016)
A Deep Insight into the Sialome of Rhodnius neglectus, a Vector of Chagas Disease Santiago PB, Assumpcao TC et al. PLoS Negl Trop Dis., doi: 10.1371/journal.pntd.0004581 (2016)
A Class of Diacylglycerol Acyltransferase 1 Inhibitors Identified by a Combination of Phenotypic High-throughput Screening, Genomics, and Genetics Tschapalda K, Zhang YQ et al. EBioMedicine., doi: 10.1016/j.ebiom.2016.04.014 (2016)
Age-related differences in the neural correlates of trial-to-trial variations of reaction time Adleman NE, Chen G, Reynolds RC, Frackman A, Razdan V, Weissman DH, Pine DS, Leibenluft E Dev Cogn Neurosci., doi: 10.1016/j.dcn.2016.05.001. (2016)
Copy Number Variation in TAS2R Bitter Taste Receptor Genes: Structure, Origin, and Population Genetics Roudnitzky N, Risso D, Drayna D, Behrens M, Meyerhof W, Wooding SP Chem Senses., DOI: 10.1093/chemse/bjw067 (2016)

Linking Genes and Brain Development of Honeybee Workers: A Whole-Transcriptome Approach Vleurinck C, Raub S, Sturgill D, Oliver B, Beye M PLoS One, doi: 10.1371/journal.pone.0157980 (2016)
Preliminary differences in resting state MEG functional connectivity pre- and post-ketamine in major depressive disorder Nugent AC, Robinson SE, Coppola R, Zarate CA Psychiatry Res, DOI://10.1016/j.pscychresns.2016.06.006 (2016)
Global intron retention mediated gene regulation during CD4+ T cell activation Ni, T; Yang, W; Han, M et al. Nucleic Acids Res., DOI://10.1093/nar/gkw591 (2016)
Estimating relative risk of a log-transformed exposure measured in pools Mitchell EM, Plowden TC, Schisterman EF Stat Med, DOI://10.1002/sim.7075 (2016)
An interactive web-based application for Comprehensive Analysis of RNAi-screen Data Dutta B, Azhir A et al. Nature Communications, doi: 10.1038/ncomms10578. (2016)
Neural Correlates of Irritability in Disruptive Mood Dysregulation and Bipolar Disorders Wiggins JL, Brotman MA, Adleman NE, Kim P, Oakes AH, Reynolds RC, Chen G, Pine DS, Leibenluft E Am J Psychiatry., doi: 10.1176/appi.ajp.2015.15060833 (2016)

Genomic insights into the Ixodes scapularis tick vector of Lyme disease Gulia-Nuss M, Nuss AB et al. Nat Commun. , doi: 10.1038/ncomms10507 (2016)
Prefrontal GABA Levels Measured With Magnetic Resonance Spectroscopy in Patients With Psychosis and Unaffected Siblings Marenco S, Meyer C, Kuo S, van der Veen JW, Shen J, DeJong K, Barnett AS, Apud JA, Dickinson D, Weinberger DR, Berman KF Am J Psychiatry, doi: 10.1176/appi.ajp.2015 (2016)
Rare copy number variants implicated in posterior urethral valves Boghossian NS, Sicko RJ et al Am J Med Genet A., doi: 10.1002/ajmg.a.37493 (2016)
Computational evaluation of exome sequence data using human and model organism phenotypes improves diagnostic efficiency Bone WP, Washington NL et al. Genet Med, doi: 10.1038/gim.2015.137 (2016)
TCRβ repertoire of CD4+ and CD8+ T cells is distinct in richness, distribution, and CDR3 amino acid composition Li HM, Hiroi T, Zhang Y, Shi A, Chen G, De S, Metter EJ, Wood WH rd, Sharov A, Milner JD, Becker KG, Zhan M, Weng NP J Leukoc Biol., doi: 10.1189/jlb.6A0215-071RR (2016)
Neural correlates of masked and unmasked face emotion processing in youth with severe mood dysregulation Tseng WL, Thomas LA, Harkins E, Pine DS, Leibenluft E, Brotman MA Soc Cogn Affect Neurosci, doi: 10.1093/scan/nsv087 (2016)

Evolving specificity of tRNA 3-methyl-cytidine-32 (m3C32) modification: a subset of tRNAsSer requires N6-isopentenylation of A37 Arimbasseri, AG; Iben, J; Wei, FY et al. RNA, DOI://10.1261/rna.056259.116 (2016)
Phosphorylation of residues inside the SNARE complex suppresses secretory vesicle fusion Malmersjo, S; Di Palma, S; Diao, J et al. EMBO J., DOI://10.15252/embj.201694071 (2016)
Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration Yu Chen, Grazyna Palczewska, et al. Sci Signal. , doi: 10.1126/scisignal.aag0245 (2016)
A simple but useful way to assess fMRI scan qualities Jonathan D. Power NeuroImage, doi:10.1016/j.neuroimage.2016.08.009 (2016)
Conformational dynamics of cancer-associated MyD88-TIR domain mutant L252P (L265P) allosterically tilts the landscape toward homo-dimerization Chendi Zhan, Ruxi Qi, Guanghong Wei, Emine Guven-Maiorov, Ruth Nussinov and Buyong Ma Protein Engineering, Design and Selection, doi: 10.1093/protein/gzw033 (2016)
Altered striatal intrinsic functional connectivity in pediatric anxiety Dorfman J, Benson B, Farber M, Pine D, Ernst M Neuropsychologia, doi: 10.1016/j.neuropsychologia.2016.03.019 (2016)

Next-generation sequencing reveals substantial genetic contribution to dementia with Lewy bodies Geiger, JT; Ding, J; Crain, B et al. Neurobiol. Dis., DOI://10.1016/j.nbd.2016.06.004 (2016)
Commonalities in Development of Pure Breeds and Population Isolates Revealed in the Genome of the Sardinian Fonni's Dog Dreger, DL; Davis, BW; Cocco, R et al. Genetics, DOI://10.1534/genetics.116.192427 (2016)
An Enantiomer of an Oral Small-Molecule TSH Receptor Agonist Exhibits Improved Pharmacologic Properties Neumann, S; Padia, U; Cullen, MJ et al. Front Endocrinol (Lausanne), DOI://10.3389/fendo.2016.00105 (2016)
PreSMA stimulation changes task-free functional connectivity in the fronto-basal-ganglia that correlates with response inhibition efficiency Xu, B; Sandrini, M; Wang, WT et al. Hum Brain Mapp, DOI://10.1002/hbm.23236 (2016)
Coffee Drinking Is Widespread in the United States but Usual Intake Varies by Key Demographic and Lifestyle Factors Erikka Loftfield, Neal D Freedman, Kevin W Dodd, Emily Vogtmann, Qian Xiao, Rashmi Sinha, and Barry I Graubard J. Nutrition, doi: 10.3945/jn.116.233940 (2016)
Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals John D. Eicher, Nathalie Chami, et al. Am. J. Hum. Genet. , doi://10.1016/j.ajhg.2016.05.005 . (2016)

AptaTRACE Elucidates RNA Sequence-Structure Motifs from Selection Trends in HT-SELEX Experiments Phuong Dao, Jan Hoinka, Mayumi Takahashi, Jiehua Zhou, Michelle Ho, Yijie Wang, Fabrizio Costa, John J. Rossi, Rolf Backofen, John Burnett, Teresa M. Przytycka Cell Systems, doi:10.1016/j.cels.2016.07.003 (2016)
C-5-Modified Tetrahydropyrano-Tetrahydofuran-Derived Protease Inhibitors (PIs) Exert Potent Inhibition of the Replication of HIV-1 Variants Highly Resistant to Various PIs, including Darunavir Manabu Aoki, Hironori Hayashi, Ravikiran S. Yedidi, Cuthbert D. Martyr, Yuki Takamatsu, Hiromi Aoki-Ogat, Teruya Nakamura, Hirotomo Nakata, Debananda Das, Yuriko Yamagata, Arun K. Ghosh and Hiroaki Mitsuya J. Virology, doi: 10.1128/JVI.01829-15 (2016)
SMAC mimetic birinapant plus radiation eradicates human head and neck cancers with genomic amplifications of cell death genes FADD and BIRC2 Danielle F Eytan, Grace E Snow, Sophie Carlson, Adeeb Derakhshan, Anthony Saleh, Stephen Schiltz, Hui Cheng, Suresh Mohan, Shaleeka Cornelius, Jamie F Coupar, Anastasia L. Sowers, Lidia Hernandez, James B. Mitchell, Christina M. Annunziata, Zhong Chen, Carter Van Waes Cancer Research, DOI: 10.1158/0008-5472.CAN-15-3317 (2016)
Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies. Demirkan A, Lahti J et al Psychol Med, doi: 10.1017/S0033291715002081 (2016)
Modeling RNA topological structures using small angle X-ray scattering Yuba R. Bhandari, Wei Jiang, Eric A. Stahlberg, Jason R. Stagno, Yun-Xing Wang Methods, doi:10.1016/j.ymeth.2016.04.015 (2016)
Comparing biomarkers as trial level general surrogates Erin E Gabriel, Michael J. Daniels, M. Elizabeth Halloran Biometrics, DOI: 10.1111/biom.12513 (2016)

Diffusive Dynamics of Contact Formation in Disordered Polypeptides Gül H. Zerze, Jeetain Mittal, and Robert B. Best Phys. Rev. Lett., doi://10.1103/PhysRevLett.116.068102 (2016)
Genome-wide cooperation by HAT Gcn5, remodeler SWI/SNF, and chaperone Ydj1 in promoter nucleosome eviction and transcriptional activation Hongfang Qiu, Razvan V. Chereji, Cuihua Hu, Hope A. Cole, Yashpal Rawal, David J. Clark, and Alan G. Hinnebusch Genome Research, doi: 10.1101/gr.196337.115 (2016)
The evolutionary turnover of recombination hot spots contributes to speciation in mice Fatima Smagulova, Kevin Brick, Yongmei Pu, R. Daniel Camerini-Otero, and Galina V. Petukhova Genes. Dev. , doi: 10.1101/gad.270009.115 (2016)
Origins of the 2009 H1N1 influenza pandemic in swine in Mexico Ignacio Mena, Martha I Nelson, et al. eLife, doi://10.7554/eLife.16777 (2016)
A Powerful Procedure for Pathway-Based Meta-analysis Using Summary Statistics Identifies 43 Pathways Associated with Type II Diabetes in European Populations Han Zhang, William Wheeler, Paula L. Hyland, Yifan Yang, Jianxin Shi, Nilanjan Chatterjee, and Kai Yu PLoS Genetics, doi: 10.1371/journal.pgen.1006122 (2016)
Evaluation of multi-echo ICA denoising for task based fMRI studies: Block designs, rapid event-related designs, and cardiac-gated fMRI Javier Gonzalez-Castillo, Puja Panwar, Laura C. Buchanan, Cesar Caballero-Gaudes, Daniel A. Handwerker, David C. Jangraw, Valentinos Zachariou, Souheil Inati, Vinai Roopchansingh, John A. Derbyshire, Peter A. Bandettini NeuroImage, doi:10.1016/j.neuroimage.2016.07.049 (2016)

Rare Variants Analysis of Cutaneous Malignant Melanoma Genes in Parkinson's Disease S.J. Lubbe, V. Escott-Price et al, the Melanoma Meta-Analysis Consortium, the International Parkinson's Disease Genomics Consortium Neurobiology of Aging, doi:10.1016/j.neurobiolaging.2016.07.013 (2016)
Crystal structure of the antigen-binding fragment of a monoclonal antibody specific for the multidrug-resistance-linked ABC transporter human P-glycoprotein Lothar Esser, Suneet Shukla, Fei Zhou, Suresh V. Ambudkar and Di Xia Acta Cryst. F, doi:10.1107/S2053230X16009778 (2016)
Certified DNA Reference Materials to Compare HER2 Gene Amplification Measurements Using Next-Generation Sequencing Methods Chih-Jian Lih, Han Si et al. J. Mol. Diag. , doi:10.1016/j.jmoldx.2016.05.008 (2016)
Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses Joyce, MG; Wheatley, AK; Thomas, PV et al. Cell, DOI://10.1016/j.cell.2016.06.043 (2016)
Characterizing human lung tissue microbiota and its relationship to epidemiological and clinical features Yu, G; Gail, MH; Consonni, D et al. Genome Biol., DOI://10.1186/s13059-016-1021-1 (2016)
Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies Joshi, AD; Andersson, C; Buch, S et al. Gastroenterology, DOI://10.1053/j.gastro.2016.04.007 (2016)
Polybrominated Diphenyl Ethers: Structure Determination and Trends in Antibacterial Activity Liu, H; Lohith, K; Rosario, M et al. J. Nat. Prod., DOI://10.1021/acs.jnatprod.6b00229 (2016)
Association of Maternal Prepregnancy Dyslipidemia With Adult Offspring Dyslipidemia in Excess of Anthropometric, Lifestyle, and Genetic Factors in the Framingham Heart Study Mendelson MM, Lyass A, O'Donnell CJ, D'Agostino RB, Levy D JAMA Cardiol, DOI://10.1001/jamacardio.2015.0304 (2016)
Comparison of Sedentary Estimates between activPAL and Hip- and Wrist-Worn ActiGraph Koster, A; Shiroma, EJ; Caserotti, P et al. Med Sci Sports Exerc, DOI://10.1249/MSS.0000000000000924 (2016)
Design strategies to address the effect of hydrophobic epitope on stability and in vitro assembly of modular virus-like particle Tekewe, A; Connors, NK; Middelberg, AP; Lua, LH; Protein Sci., DOI://10.1002/pro.2953 (2016)
South (S)- and North (N)-Methanocarba-7-Deazaadenosine Analogues as Inhibitors of Human Adenosine Kinase Kiran S. Toti, Danielle Osborne, Antonella Ciancetta, Detlev Boison, and Kenneth A. Jacobson J. Med. Chem. , DOI: 10.1021/acs.jmedchem.6b00689 (2016)
Change in Epigenome-Wide DNA Methylation Over 9 Years and Subsequent Mortality: Results From the InCHIANTI Study Moore, AZ; Hernandez, DG; Tanaka, T et al. J. Gerontol. A Biol. Sci. Med. Sci., DOI://10.1093/gerona/glv118 (2016)

A Cascade of Wnt, Eda, and Shh Signaling Is Essential for Touch Dome Merkel Cell Development Xiao, Y; Thoresen, DT; Miao, L et al. PLoS Genet., DOI://10.1371/journal.pgen.1006150 (2016)
Complete Genome Sequence of a Klebsiella pneumoniae Strain Carrying blaNDM-1 on a Multidrug Resistance Plasmid Conlan S, Lau AF, , Palmore TN, Frank KM, Segre JA Genome Announc, DOI://10.1128/genomeA.00664-16 (2016)
Computational study of the inhibitory mechanism of the kinase CDK5 hyperactivity by peptide p5 and derivation of a pharmacophore A. Cardone, M. Brady, R. Sriram, H. C. Pant, S. A. Hassan J. Computer-Aided Molecular Design, DOI: 10.1007/s10822-016-9922-3 (2016)
A Comparison Study of Fixed and Mixed Effect Models for Gene Level Association Studies of Complex Traits Ruzong Fan, Chi-yang Chiu, Jeesun Jung, Daniel E. Weeks, Alexander F. Wilson, Joan E. Bailey-Wilson, Christopher I. Amos, Zhen Chen, James L. Mills and Momiao Xiong Genetic Epidemiology, DOI: 10.1002/gepi.21984 (2016)
Mutational Spectrum of MYO15A and the Molecular Mechanisms of DFNB3 Human Deafness Atteeq U. Rehman, Jonathan E. Bird, Rabia Faridi, Mohsin Shahzad, Sujay Shah, Kwanghyuk Lee, Shaheen N. Khan, Ayesha Imtiaz, Zubair M. Ahmed, Saima Riazuddin, Regie Lyn P. Santos- Cortez, Wasim Ahmad, Suzanne M. Leal, Sheikh Riazuddin, Thomas B. Friedman Human Mutation, DOI: 10.1002/humu.23042 (2016)
Transmission-blocking activity is determined by transmission-reducing activity and number of control oocysts in Plasmodium falciparum standard membrane-feeding assay Kazutoyo Miura, Bruce J. Swihart, Bingbing Deng, Luwen Zhou, Thao P. Pham, Ababacar Diouf, Timothy Burton, Michael P. Fay, Carole A. Long Vaccine, doi:10.1016/j.vaccine.2016.06.066 (2016)

Tyrosine-sulfated V2 peptides inhibit HIV-1 infection via coreceptor mimicry Raffaello Cimbro, Francis C. Peterson, Qingbo Liu, Christina Guzzo, Peng Zhang, Huiyi Miao, Donald Van Ryk, Xavier Ambroggio, Darrell E. Hurt, Luca De Gioia, Brian F. Volkman, Michael A. Dolan, Paolo Lusso EBioMedicine, doi:10.1016/j.ebiom.2016.06.037 (2016)
Defining the neuroanatomic basis of motor coordination in children and its relationship with symptoms of attention-deficit/hyperactivity disorder Shaw, P; Weingart, D; Bonner, T et al. Psychol Med, DOI://10.1017/S0033291716000660 (2016)
Common Variation in the DOPA Decarboxylase (DDC) Gene and Human Striatal DDC Activity In Vivo Eisenberg, DP; Kohn, PD; Hegarty, CE et al. Neuropsychopharmacology, DOI://10.1038/npp.2016.31 (2016)
Improving Motor Corticothalamic Communication After Stroke Using Real-Time fMRI Connectivity-Based Neurofeedback Liew, SL; Rana, M; Cornelsen, S et al. Neurorehabil Neural Repair, DOI://10.1177/1545968315619699 (2016)
Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits Chami, N; Chen, MH; Slater, AJ et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2016.05.007 (2016)
Pathogenic role of B-cell receptor signaling and canonical NF-κB activation in mantle cell lymphoma Saba, NS; Liu, D; Herman, SE et al. Blood, DOI://10.1182/blood-2015-11-681460 (2016)
Chromatin Landscape of the IRF Genes and Role of the Epigenetic Reader BRD4 Bachu, M; Dey, A; Ozato, K; J. Interferon Cytokine Res., DOI://10.1089/jir.2015.0179 (2016)
Fine-tuning of CD8(+) T-cell effector functions by targeting the 2B4-CD48 interaction Lissina, A; Ambrozak, DR; Boswell, KL et al. Immunol. Cell Biol., DOI://10.1038/icb.2016.17 (2016)
Dataset of Arabidopsis plants that overexpress FT driven by a meristem-specific KNAT1 promoter Duplat-Bermúdez, L; Ruiz-Medrano, R; Landsman, D; Mariño-Ramírez, L; Xoconostle-Cázares, B; Data Brief, DOI://10.1016/j.dib.2016.06.002 (2016)
The genetic regulatory signature of type 2 diabetes in human skeletal muscle Scott, LJ; Erdos, MR; Huyghe, JR et al. Nat Commun, DOI://10.1038/ncomms11764 (2016)
Plasmid Dynamics in KPC-Positive Klebsiella pneumoniae during Long-Term Patient Colonization Conlan, S; Park, M; Deming, C et al. MBio, DOI://10.1128/mBio.00742-16 (2016)
Structure-Based Design of 3-(4-Aryl-1H-1,2,3-triazol-1-yl)-Biphenyl Derivatives as P2Y14 Receptor Antagonists Anna Junker, Ramachandran Balasubramanian, Antonella Ciancetta, Elisa Uliassi, Evgeny Kiselev, Chiara Martiriggiano, Kevin Trujillo, Giorgi Mtchedlidze, Leah Birdwell, Kyle A. Brown, T. Kendall Harden, and Kenneth A. Jacobson J. Med. Chem. , DOI: 10.1021/acs.jmedchem.6b00044 (2016)

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases Salman M. Tajuddin, Ursula M. Schick et al. Am. J. Hum. Genet., doi:10.1016/j.ajhg.2016.05.003 (2016)
Coarse Master Equations for Binding Kinetics of Amyloid Peptide Dimers Cathal T. Leahy, Ronan D. Murphy, Gerhard Hummer, Edina Rosta, and Nicolae-Viorel Buchete J. Phys. Chem. Lett., DOI: 10.1021/acs.jpclett.6b00518 (2016)
Recruitment of Rod Photoreceptors from Short-Wavelength-Sensitive Cones during the Evolution of Nocturnal Vision in Mammals Jung-Woong Kim, Hyun-Jin Yang, Adam Phillip Oel, Matthew John Brooks, Li Jia, David Charles Plachetzki, Wei Li, William Ted Allison, Anand Swaroop Developmental Cell, doi:10.1016/j.devcel.2016.05.023 (2016)
Enhanced exo-inulinase activity and stability by fusion of an inulin-binding module Shun-Hua Zhou, Yuan Liu, Yu-Juan Zhao, Zhe Chi, Zhen-Ming Chi, Guang-Lei Liu Applied Microbiology and Biotechnology, doi:10.1007/s00253-016-7587-4 (2016)
Ring Catalog: A resource for designing self-assembling RNA nanostructures Parlea, L; Bindewald, E; Sharan, R et al. Methods, DOI://10.1016/j.ymeth.2016.04.016 (2016)
Decreased subcortical volumes in alcohol dependent individuals: effect of polysubstance use disorder Grodin EN, Momenan R Addict Biol, DOI://10.1111/adb.12421 (2016)

Compressed Sensing Electron Tomography for Determining Biological Structure Matthew D. Guay, Wojciech Czaja, Maria A. Aronova & Richard D. Leapman Nature, doi:10.1038/srep27614 (2016)
Next generation sequencing technology and genomewide data analysis: Perspectives for retinal research Vijender Chaitankar, Gokhan Karakulah, Rinki Ratnapriya, Felipe O. Giuste, Matthew J. Brooks, Anand Swaroop Progress in Retinal and Eye Research, doi:10.1016/j.preteyeres.2016.06.001 (2016)
Taz1-Shelterin Promotes Facultative Heterochromatin Assembly at Chromosome-Internal Sites Containing Late Replication Origins Zofall M, Smith DR, Mizuguchi T, Dhakshnamoorthy J, Grewal SI Mol. Cell, DOI://10.1016/j.molcel.2016.04.034 (2016)
The homeoprotein DLX3 and tumor suppressor p53 co-regulate cell cycle progression and squamous tumor growth Palazzo, E; Kellett, M; Cataisson, C et al. Oncogene, DOI://10.1038/onc.2015.380 (2016)
Impact of Type 2 Diabetes on Impaired Kidney Function in Sub-Saharan African Populations Adebamowo, SN; Adeyemo, AA; Tekola-Ayele, F et al. Front Endocrinol (Lausanne), DOI://10.3389/fendo.2016.00050 (2016)
Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8 Soto, C; Ofek, G; Joyce, MG et al. PLoS ONE, DOI://10.1371/journal.pone.0157409 (2016)

Mapping of Ebolavirus Neutralization by Monoclonal Antibodies in the ZMapp Cocktail Using Cryo-Electron Tomography and Studies of Cellular Entry Erin E. H. Tran, Elizabeth A. Nelson, Pranay Bonagiri, James A. Simmons, Charles J. Shoemaker, Connie S . Schmaljohn, Gary P. Kobinger, Larry Zeitlin, Sriram Subramaniam, and Judith M. White J. Virol., doi:10.1128/JVI.00406-16 (2016)
Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response M L Nickerson, N Witte, K M Im, S Turan, C Owens, K Misner, S X Tsang, Z Cai, S Wu, M Dean, J C Costello and D Theodorescu Oncogene, doi: 10.1038/onc.2016.172 (2016)
Regulation of normal B-cell differentiation and malignant B-cell survival by OCT2 Hodson, DJ; Shaffer, AL; Xiao, W et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1600557113 (2016)
A replicator-specific binding protein essential for site-specific initiation of DNA replication in mammalian cells Zhang, Y; Huang, L; Fu, H et al. Nat Commun, DOI://10.1038/ncomms11748 (2016)
Decreased Expression of Retinoid X Receptors During Human and Azoxymethane-induced Colorectal Carcinogenesis in the Rat Hao, X; Xiao, H; Ju, J; Hewitt, SM; Morse, HC; Anticancer Res., 1791-7530 (2016)
H19ICR mediated transcriptional silencing does not require target promoter methylation Gebert C, Rong Q, Jeong S, Iben J, Pfeifer K Biochem. Biophys. Res. Commun., DOI://10.1016/j.bbrc.2016.05.042 (2016)

Chemoreception and neuroplasticity in respiratory circuits William H. Barnett, Ana P. Abdala, Julian F.R. Paton, Ilya A. Rybak, Daniel B. Zoccal, Yaroslav I. Molkov Experimental Neurology, doi:10.1016/j.expneurol.2016.05.036 (2016)
A novel complete-case analysis to determine statistical significance between treatments in an intention-to-treat population of randomized clinical trials involving missing data Wei Liu, Jinhui Ding Stat. Methods in Med. Res. , doi: 10.1177/0962280216651307 (2016)
Urinary Metabolite Risk Biomarkers of Lung Cancer: A Prospective Cohort Study Haznadar, M; Cai, Q; Krausz, KW et al. Cancer Epidemiol. Biomarkers Prev., DOI://10.1158/1055-9965.EPI-15-1191 (2016)
Prenatal immune programming of the sex-dependent risk for major depression Gilman, SE; Cherkerzian, S; Buka, SL; Hahn, J; Hornig, M; Goldstein, JM; Transl Psychiatry, DOI://10.1038/tp.2016.91 (2016)
Polycomb Ezh2 controls the fate of GABAergic neurons in the embryonic cerebellum Feng, X; Juan, AH; Wang, HA; Ko, KD; Zare, H; Sartorelli, V; Development, DOI://10.1242/dev.132902 (2016)
Transcriptomic analysis of Arabidopsis overexpressing flowering locus T driven by a meristem-specific promoter that induces early flowering Duplat-Bermúdez, L; Ruiz-Medrano, R; Landsman, D; Mariño-Ramírez, L; Xoconostle-Cázares, B; Gene, DOI://10.1016/j.gene.2016.04.060 (2016)

Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery Alan Merk , Alberto Bartesaghi , Soojay Banerjee , Veronica Falconieri , Prashant Rao , Mindy I. Davis , Rajan Pragani , Matthew B. Boxer , Lesley A. Earl , Jacqueline L.S. Milne , Sriram Subramaniam Cell, doi://10.1016/j.cell.2016.05.040 show (2016)
Robertsonian translocations modify genomic distribution of γH2AFX and H3.3 in mouse germ cells Fayer S, Yu Q, Kim J, Moussette S, Camerini-Otero RD, Naumova AK Mamm. Genome, DOI://10.1007/s00335-016-9630-2 (2016)
Structural Basis for the Failure of the C1 Domain of Ras Guanine Nucleotide Releasing Protein 2 (RasGRP2) to Bind Phorbol Ester with High Affinity Czikora, A; Lundberg, DJ; Abramovitz, A et al. J. Biol. Chem., DOI://10.1074/jbc.M116.725333 (2016)
Genome-wide association study identifies 74 loci associated with educational attainment Okbay, A; Beauchamp, JP; Fontana, MA et al. Nature, DOI://10.1038/nature17671 (2016)
Proinflammatory and lipid biomarkers mediate metabolically healthy obesity: A proteomics study Doumatey AP, Zhou J, Zhou M, Prieto D, Rotimi CN, Adeyemo A Obesity (Silver Spring), DOI://10.1002/oby.21482 (2016)
Encoding of Touch Intensity But Not Pleasantness in Human Primary Somatosensory Cortex Case, LK; Laubacher, CM; Olausson, H; Wang, B; Spagnolo, PA; Bushnell, MC; J. Neurosci., DOI://10.1523/JNEUROSCI.1130-15.2016 (2016)
Trajectories of microsecond molecular dynamics simulations of nucleosomes and nucleosome core particles Alexey K. Shaytan, Grigoriy A. Armeev, Alexander Goncearenco, Victor B. Zhurkin, David Landsman, Anna R. Panchenko Data in Brief, doi:10.1016/j.dib.2016.04.073 (2016)
A Transcriptionally Inactive ATF2 Variant Drives Melanomagenesis Giuseppina Claps, Yann Cheli, Tongwu Zhang, Marzia Scortegagna, Eric Lau, Hyungsoo Kim, Jianfei Qi, Jian-Liang Li, Brian James, Andreas Dzung, Mitchell P. Levesque, Reinhard Dummer, Nicholas K. Hayward, Marcus Bosenberg, Kevin M. Brown, Ze'ev A. Ronai Cell Reports, doi:10.1016/j.celrep.2016.04.072 (2016)
Untangling the relatedness among correlations, part I: Nonparametric approaches to inter-subject correlation analysis at the group level Gang Chen, Yong-Wook Shin, Paul A. Taylor, Daniel Glen, Richard C. Reynolds, Robert B. Israel, Robert W. Cox NeuroImage, doi:10.1016/j.neuroimage.2016.05.023 (2016)
Confidence assignment for mass spectrometry based peptide identifications via the extreme value distribution Gelio Alves and Yi-Kuo Yu Bioinformatics, doi: 10.1093/bioinformatics/btw22 (2016)
A single endoplasmic reticulum aminopeptidase-1 protein allotype is a strong risk factor for Behçet's disease in HLA-B*51 carriers. Takeuchi, M; Ombrello, MJ; Kirino, Y et al. Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2015-209059 (2016)
Ancient Human Migration after Out-of-Africa Shriner D, Tekola-Ayele F, Adeyemo A, Rotimi CN Sci Rep, DOI://10.1038/srep26565 (2016)

Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes Stoehr, A; Yang, Y; Patel, S et al. Cardiovasc. Res., DOI://10.1093/cvr/cvw081 (2016)
Comprehensive Database of Human E3 Ubiquitin Ligases: Application to Aquaporin-2 Regulation Barbara Medvar, Viswanathan Raghuram, Trairak Pisitkun, Abhijit Sarkar, Mark A. Knepper Physiological Genomics, DOI: 10.1152/physiolgenomics.00031.2016 (2016)
Identification of modes of interactions between 9-aminoacridine hydrochloride hydrate and serum proteins by low and high resolution spectroscopy and molecular modeling Piyali Mitra, Uttam Pal, Nakul Chandra Maiti, Anirban Ghosh, Anirban Bhunia and Samita Basu Roy. Soc. Chem. , DOI: 10.1039/C6RA04140J (2016)
OptSSeq: High-throughput sequencing readout of growth enrichment defines optimal gene expression elements for homoethanologenesis Indro Neil Ghosh, and Robert Landick ACS Synthetic Biology, DOI: 10.1021/acssynbio.6b00121 (2016)
Predicting motor improvement after stroke with clinical assessment and diffusion tensor imaging Buch, ER; Rizk, S; Nicolo, P; Cohen, LG; Schnider, A; Guggisberg, AG; Neurology, DOI://10.1212/WNL.0000000000002675 (2016)
Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions Villarino A, Laurence A, Robinson GW, Bonelli M, Dema B, Afzali B, Shih HY, Sun HW, Brooks SR, Hennighausen L, Kanno Y, O'Shea JJ Elife, doi: 10.7554/eLife.08384 (2016)

Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality Han-Yu Shih, Giuseppe Sciumè, Yohei Mikami, Liying Guo, Hong-Wei Sun, Stephen R. Brooks, Joseph F. Urban Jr., Fred P. Davis, Yuka Kanno, John J. O'Shea Cell, doi:10.1016/j.cell.2016.04.029 (2016)
BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin Ballachanda N Devaiah, Chanelle Case-Borden, Anne Gegonne, Chih Hao Hsu, Qingrong Chen, Daoud Meerzaman, Anup Dey, Keiko Ozato & Dinah S Singer Nature Structural & Molecular Biology, doi:10.1038/nsmb.3228 (2016)
Temporal Stability of the Human Skin Microbiome Julia Oh, Allyson L. Byrd , Morgan Park , NISC Comparative Sequencing Program, Heidi H. Kong, Julia A. Segre Cell, doi://10.1016/j.cell.2016.04.008 (2016)
Colorectal Cancer and the Human Gut Microbiome: Reproducibility with Whole-Genome Shotgun Sequencing Emily Vogtmann, Xing Hua, Georg Zeller, Shinichi Sunagawa, Anita Y. Voigt, Rajna Hercog, James J. Goedert, Jianxin Shi, Peer Bork, Rashmi Sinha PLoS One, doi://10.1371/journal.pone.0155362 (2016)
Cryo-EM analysis of the conformational landscape of human P-glycoprotein (ABCB1) during its catalytic cycle Gabriel Frank, Suneet Shukla, Prashant Rao, Mario J Borgnia, Alberto Bartesaghi, Alan Merk, Aerfa Mobin, Lothar Esser, Lesley A. Earl, Michael M Gottesman, Di Xia, Suresh V. Ambudkar, and Sriram Subramaniam Molecular Pharmacology, doi: 10.1124/mol.116.104190 (2016)
Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody Kong, R; Xu, K; Zhou, T et al. Science, DOI://10.1126/science.aae0474 (2016)

Analysis of mcDESPOT- and CPMG-derived parameter estimates for two-component nonexchanging systems Bouhrara M, Reiter DA, Celik H, Fishbein KW, Kijowski R, Spencer RG Magn Reson Med, DOI://10.1002/mrm.25801 (2016)
Interferon Regulator Factor 8 (IRF8) Limits Ocular Pathology during HSV-1 Infection by Restraining the Activation and Expansion of CD8+ T Cells Sun, L; St Leger, AJ; Yu, CR et al. PLoS ONE, DOI://10.1371/journal.pone.0155420 (2016)
Delineation of Polypharmacology across the Human Structural Kinome Using a Functional Site Interaction Fingerprint Approach Zhao Z, Xie L, Xie L, Bourne PE J. Med. Chem., DOI://10.1021/acs.jmedchem.5b02041 (2016)
Distinct epigenetic features of differentiation-regulated replication origins Smith, OK; Kim, R; Fu, H et al. Epigenetics Chromatin, DOI://10.1186/s13072-016-0067-3 (2016)
Structural Determinants of Misfolding in Multidomain Proteins Pengfei Tian and Robert B. Best PLoS Computational Biology, 10.1371/journal.pcbi.1004933 (2016)
Learned Value Shapes Responses to Objects in Frontal and Ventral Stream Networks in Macaque Monkeys Kaskan, PM; Costa, VD; Eaton, HP et al. Cereb. Cortex, DOI://10.1093/cercor/bhw113 (2016)

CLIP-seq to Identify KSHV ORF57-Binding RNA in Host B Cells Ma Y, Liu P, Majerciak V, Zhu J, Zheng ZM Curr Protoc Microbiol, DOI://10.1002/cpmc.3 (2016)
Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G Stewart-Jones, GB; Soto, C; Lemmin, T et al. Cell, DOI://10.1016/j.cell.2016.04.010 (2016)
PA-seq for Global Identification of RNA Polyadenylation Sites of Kaposi's Sarcoma-Associated Herpesvirus Transcripts Ni T, Majerciak V, Zheng ZM, Zhu J Curr Protoc Microbiol, DOI://10.1002/cpmc.1 (2016)
Genome Sequence of the Banana Plant Growth-Promoting Rhizobacterium Pseudomonas fluorescens PS006 Gamez, RM; Rodríguez, F; Ramírez, S et al. Genome Announc, DOI://10.1128/genomeA.00329-16 (2016)
Sparse signal representation in digital and biological system Matthew Guay PhD Thesis, University of Maryland (2016)
Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways Psaila, B; Barkas, N; Iskander, D et al. Genome Biol., DOI://10.1186/s13059-016-0939-7 (2016)

Identification of an Immunogenic Subset of Metastatic Uveal Melanoma Rothermel, LD; Sabesan, AC; Stephens, DJ et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-15-2294 (2016)
Regional Variations in Brain Gyrification Are Associated with General Cognitive Ability in Humans Michael D. Gregory, J. Shane Kippenhan, Dwight Dickinson, Jessica Carrasco, Venkata S. Mattay, Daniel R. Weinberger, Karen F. Berman Current Biology, doi:10.1016/j.cub.2016.03.021 (2016)
A Common Polymorphism in HIBCH Influences Methylmalonic Acid Concentrations in Blood Independently of Cobalamin Anne M. Molloy, Faith Pangilinan , et al. Am. J. Hum. Genet., DOI:10.1016/j.ajhg.2016.03.005 show (2016)
Arginine kinase from Myzostoma cirriferum, a basal member of annelids Daichi Yano, Sayo Mimura, Kouji Uda, Tomohiko Suzuki Comparative Biochemistry and Physiology Part B: Biochemistry, doi:10.1016/j.cbpb.2016.04.004 (2016)
TNF-α modulates genome-wide redistribution of ΔNp63α/TAp73 and NF-κB cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer Si, H; Lu, H; Yang, X et al. Oncogene, DOI://10.1038/onc.2016.112 (2016)
DR-TAMAS: Diffeomorphic Registration for Tensor Accurate Alignment of Anatomical Structures Irfanoglu, MO; Nayak, A; Jenkins, J et al. Neuroimage, DOI://10.1016/j.neuroimage.2016.02.066 (2016)

Challenges in studying the structures of metal- amyloid oligomers related to type 2 diabetes, parkinson's disease, and alzheimer's disease Vered Wineman-Fisher, Daniel Nir Bloch, Yifat Miller Coordination Chemistry Reviews, doi:10.1016/j.ccr.2016.04.010 (2016)
Using cryo-EM to map small ligands on dynamic metabolic enzymes: Studies with glutamate dehydrogenase Mario J. Borgnia, Soojay Banerjee, Alan Merk, Doreen Matthies, Alberto Bartesaghi, Prashant Rao, Jason Pierson, Lesley A. Earl, Veronica Falconieri, Sriram Subramaniam, and Jacqueline L. S. Milne Molecular Pharmacology, doi: 10.1124/mol.116.103382 (2016)
Membrane-associated Ras dimers are isoform-specific: K-Ras dimers differ from H-Ras dimers Hyunbum Jang, Serena Muratcioglu, Attila Gursoy, Ozlem Keskin, Ruth Nussinov Biochemical J., DOI: 10.1042/BCJ20160031 (2016)
Plasmid-Based Materials as Multiplex Quality Controls and Calibrators for Clinical Next-Generation Sequencing Assays David J. Sims, Robin D. Harrington, Eric C. Polley, Thomas D. Forbes, Michele G. Mehaffey, Paul M. McGregor III, Corinne E. Camalier, Kneshay N. Harper, Courtney H. Bouk, Biswajit Das, Barbara A. Conley, James H. Doroshow, P. Mickey Williams, Chih-Jian Lih J. Molecular Diagnostics, doi:10.1016/j.jmoldx.2015.11.008 (2016)
High-level expression of Proteinase K from Tritirachium album Limber in Pichia pastoris using multi-copy expression strains Yang, H; Zhai, C; Yu, X et al. Protein Expr. Purif., DOI://10.1016/j.pep.2016.02.006 (2016)
Laminopathies disrupt epigenomic developmental programs and cell fate Perovanovic, J; Dell'Orso, S; Gnochi, VF et al. Sci Transl Med, DOI://10.1126/scitranslmed.aad4991 (2016)

Tracking brain arousal fluctuations with fMRI Chang, C; Leopold, DA; Schölvinck, ML et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1520613113 (2016)
Structure-based designing of sordarin derivative as potential fungicide with pan-fungal activity Biprashekhar Chakrabortya, Nikunjkumar Vinodray Sejpalb, Pavan V. Payghana, Nanda Ghoshala, Jayati Sengupta J. Mol. Graph. Model. , doi:10.1016/j.jmgm.2016.03.013 (2016)
The Ancient Evolutionary History of Polyomaviruses Buck, CB; Van Doorslaer, K; Peretti, A et al. PLoS Pathog., DOI://10.1371/journal.ppat.1005574 (2016)
BIG: A large-scale data integration tool for renal physiology Yue Zhao, Chin-Rang Yang, Viswanathan Raghuram, Jaya Parulekar, Mark A. Knepper Am. J. Physiol. Renal Physiol. , DOI: 10.1152/ajprenal.00249.2016 (2016)
An Integrated Genome-Wide Systems Genetics Screen for Breast Cancer Metastasis Susceptibility Genes Ling Bai, Howard H. Yang, Ying Hu, Anjali Shukla, Ngoc-Han Ha, Anthony Doran, Farhoud Faraji, Natalie Goldberger, Maxwell P. Lee, Thomas Keane, Kent W. Hunter PLoS Genetics, doi://10.1371/journal.pgen.1005989 (2016)
Biallelic BRCA2 Mutations Shape the Somatic Mutational Landscape of Aggressive Prostate Tumors Brennan Decker, Danielle M. Karyadi, Brian W. Davis, Eric Karlins, Lori S. Tillmans, Janet L. Stanford, Stephen N. Thibodeau, Elaine A. Ostrander Am. J. Hum. Genet. , doi:10.1016/j.ajhg.2016.03.003 (2016)

Characterization of influenza vaccine hemagglutinin complexes by cryo-electron microscopy and image analyses reveals structural polymorphisms Dustin M. McCraw, John R. Gallagher and Audray K. Harris Clin. Vaccine Immunol. , oi:10.1128/CVI.00085-16 (2016)
Adaptation of pancreatic islet cyto-architecture during development Deborah A Striegel, Manami Hara and Vipul Periwal Physical Biology, doi://10.1088/1478-3975/13/2/025004 (2016)
Low-frequency and common genetic variation in ischemic stroke R Malik, M Traylor et al. Neurology, doi://10.1212/WNL.0000000000002528 (2016)
Purine (N)-Methanocarba Nucleoside Derivatives Lacking an Exocyclic Amine as Selective A3 Adenosine Receptor Agonists Tosh, DK; Ciancetta, A; Warnick, E et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.5b01998 (2016)
Comparison of normalization and differential expression analyses using RNA-Seq data from 726 individual Drosophila melanogaster Lin Y, Golovnina K, Chen ZX, Lee HN, Negron YL, Sultana H, Oliver B, Harbison ST BMC Genomics, doi: 10.1186/s12864-015-2353-z (2016)
Novel Analogues of (R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity Zou, MF; Keck, TM; Kumar, V et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.5b01612 (2016)

Fatty Acid Oxidation is Impaired in An Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease Menezes LF, Lin CC, Zhou F, Germino GG EBioMedicine, 2352-3964 (2016)
Temperature-Dependent Conformational Properties of Human Neuronal Calcium Sensor-1 Protein Revealed by All-Atom Simulations Zhu Y, Ma B, Qi R, Nussinov R, Zhang Q J Phys Chem B, DOI://10.1021/acs.jpcb.5b12299 (2016)
Linear Discriminant Analysis Achieves High Classification Accuracy for the BOLD fMRI Response to Naturalistic Movie Stimuli Mandelkow, H; de Zwart, JA; Duyn, JH; Front Hum Neurosci, DOI://10.3389/fnhum.2016.00128 (2016)
Evidence for N-Terminal Myristoylation of Tetrahymena Arginine Kinase Using Peptide Mass Fingerprinting Analysis Shou Motomura, Tomohiko Suzuki Protein J. , doi://10.1007/s10930-016-9663-0 (2016)
Axial superresolution via multiangle TIRF microscopy with sequential imaging and photobleaching Yan Fu, Peter W. Winter, Raul Rojas, Victor Wang, Matthew McAuliffe, and George H. Patterson PNAS, doi: 10.1073/pnas.1516715113 (2016)
Repertoires of Spike Avalanches Are Modulated by Behavior and Novelty Tiago L. Ribeiro, Sidarta Ribeiro and Mauro Copelli Frontiers in Neural Circuits, doi:///10.3389/fncir.2016.00016 (2016)

Characterization of the platelet transcriptome by RNA sequencing in patients with acute myocardial infarction Eicher, JD; Wakabayashi, Y; Vitseva, O et al. Platelets, DOI://10.3109/09537104.2015.1083543 (2016)
The Human Physiome: how standards, software and innovative service infrastructures are providing the building blocks to make it achievable Nickerson, D; Atalag, K; de Bono, B et al. Interface Focus, DOI://10.1098/rsfs.2015.0103 (2016)
Distinguishing highly similar gene isoforms with a clustering-based bioinformatics analysis of PacBio single-molecule long reads Liang, M; Raley, C; Zheng, X et al. BioData Min, DOI://10.1186/s13040-016-0090-8 (2016)
Structure and function of the AAA+ ATPase p97/Cdc48p Xia D, Tang WK, Ye Y Gene, DOI://10.1016/j.gene.2016.02.042 (2016)
Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome Falcone, EL; Abusleme, L; Swamydas, M et al. Microbiome, DOI://10.1186/s40168-016-0159-0 (2016)
MultiDimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A Report from the Center for Cancer Research Wendy Chang, Andrew Brohl, Rajesh Patidar, Sivasish Sindiri, Jack F. Shern, Jun S. Wei, Young K. Song, Marielle E Yohe, Berkley E. Gryder, Shile Zhang, Kathleen A Calzone, Nityashree Shivaprasad, Xinyu Wen, Thomas Badgett, Markku Miettinen, Kip R Hartman, James C League-Pascual, Toby Trahair, Brigitte C. Widemann, Melinda S. Merchant, Rosandra N Kaplan, Jimmy C Lin, and Javed Khan Clinical Cancer Research, doi: 10.1158/1078-0432.CCR-15-2717 (2016)
Aberrant intrinsic functional connectivity within and between corticostriatal and temporal-parietal networks in adults and youth with bipolar disorder Stoddard, J; Gotts, SJ; Brotman, MA et al. Psychol Med, DOI://10.1017/S0033291716000143 (2016)
Cajal bodies are linked to genome conformation Qiuyan Wang, Iain A. Sawyer, Myong-Hee Sung, David Sturgill, Sergey P. Shevtsov, Gianluca Pegoraro, Ofir Hakim, Songjoon Baek, Gordon L. Hager & Miroslav Dundr Nature Communications, doi:10.1038/ncomms10966 (2016)
Cryo-electron Microscopy Structures of Chimeric Hemagglutinin Displayed on a Universal Influenza Vaccine Candidate Erin E. H. Tran, Kira A. Podolsky, Alberto Bartesaghi, Oleg Kuybeda, Giovanna Grandinetti, Teddy John Wohlbold, Gene S. Tan, Raffael Nachbagauer, Peter Palese, Florian Krammer, Sriram Subramaniam mBio, doi: 10.1128/mBio.00257-16 (2016)
Subtle in-scanner motion biases automated measurement of brain anatomy from in vivo MRI Aaron Alexander-Bloch, Liv Clasen, Michael Stockman, Lisa Ronan, Francois Lalonde, Jay Giedd and Armin Raznahan Human Brain Mapping, DOI: 10.1002/hbm.23180 (2016)
Detection of benign prostatic hyperplasia nodules in T2W MR images using fuzzy decision forest Nathan Lay ; Sabrina Freeman ; Baris Turkbey ; Ronald Summers SPIE Proceedings, doi:10.1117/12.2217906 (2016)
2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition Soojay Banerjee, Alberto Bartesaghi, Alan Merk, Prashant Rao, Stacie L. Bulfer, Yongzhao Yan, Neal Green, Barbara Mroczkowski, R. Jeffrey Neitz, Peter Wipf, Veronica Falconieri, Raymond J. Deshaies, Jacqueline L. S. Milne, Donna Huryn, Michelle Arkin, Sriram Subramaniam Science, DOI: 10.1126/science.aad7974 (2016)

Design and synthesis of small molecule-sulfotyrosine mimetics that inhibit HIV-1 entry Dogo-Isonagie, C; Lee, SL; Lohith, K et al. Bioorg. Med. Chem., DOI://10.1016/j.bmc.2016.02.044 (2016)
Detection and Whole-Genome Sequencing of Carbapenemase-Producing Aeromonas hydrophila Isolates from Routine Perirectal Surveillance Culture Hughes, HY; Conlan, SP; Lau, AF et al. J. Clin. Microbiol., DOI://10.1128/JCM.03229-15 (2016)
Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers Robles, AI; Traverso, G; Zhang, M et al. Gastroenterology, DOI://10.1053/j.gastro.2015.12.036 (2016)
Emerging Functions of Natural IgM and Its Fc Receptor FCMR in Immune Homeostasis Wang, H; Coligan, JE; Morse, HC; Front Immunol, DOI://10.3389/fimmu.2016.00099 (2016)
A molecular threshold for effector CD8(+) T cell differentiation controlled by transcription factors Blimp-1 and T-bet Xin, A; Masson, F; Liao, Y et al. Nat. Immunol., DOI://10.1038/ni.3410 (2016)
caOmicsV: an R package for visualizing multidimensional cancer genomic data Zhang H, Meltzer PS, Davis SR BMC Bioinformatics, DOI://10.1186/s12859-016-0989-6 (2016)
Brain-Derived Neurotrophic Factor Val66Met Polymorphism Affects the Relationship Between an Anxiety-Related Personality Trait and Resting Regional Cerebral Blood Flow Wei, SM; Eisenberg, DP; Nabel, KG et al. Cereb. Cortex, DOI://10.1093/cercor/bhw072 (2016)
Redox-induced activation of the proton pump in the respiratory complex I Vivek Sharma, Galina Belevich, Ana P. Gamiz-Hernandez, Tomasz Ròg, Ilpo Vattulainen, Marina L. Verkhovskaya Mårten Wikström, Gerhard Hummer, and Ville R. I. Kaila PNAS, doi://10.1073/pnas.1503761112 (2016)
High-level expression and characterization of a novel serine protease in Pichia pastoris by multi-copy integration Min Shu, Wei Shen, Shihui Yang , Xiaojuan Wang , Fei Wang , Yaping Wang , Lixin Ma Enzyme and Microbioal Technology, doi:10.1016/j.enzmictec.2016.06.007 (2016)
NMDA Receptors Multiplicatively Scale Visual Signals and Enhance Directional Motion Discrimination in Retinal Ganglion Cells Poleg-Polsky A, Diamond JS Neuron, DOI://10.1016/j.neuron.2016.02.013 (2016)
MEGSA: A Powerful and Flexible Framework for Analyzing Mutual Exclusivity of Tumor Mutations Xing Hua, Paula L. Hyland, Jing Huang, Lei Song, Bin Zhu, Neil E. Caporaso, Maria Teresa Landi, Nilanjan Chatterjee, and Jianxin Shi Am J. Hum. Genet. , doi://10.1016/j.ajhg.2015.12.021 (2016)
Characterizing the Covalent Targets of a Small Molecule Inhibitor of the Lysine Acetyltransferase P300 Shrimp JH, Sorum AW, Garlick JM, Guasch L, Nicklaus MC, Meier JL ACS Med Chem Lett, DOI://10.1021/acsmedchemlett.5b00385 (2016)
Plasticity of Sensorimotor Networks: Multiple Overlapping Mechanisms Buch, ER; Liew, SL; Cohen, LG; Neuroscientist, DOI://10.1177/1073858416638641 (2016)
Critical Nucleus Structure and Aggregation Mechanism of the C-terminal Fragment of Copper-Zinc Superoxide Dismutase Protein Zou Y, Sun Y, Zhu Y, Ma B, Nussinov R, Zhang Q ACS Chem Neurosci, DOI://10.1021/acschemneuro.5b00242 (2016)
Seeking Optimal Region-Of-Interest (ROI) Single-Value Summary Measures for fMRI Studies in Imaging Genetics Tong, Y; Chen, Q; Nichols, TE et al. PLoS ONE, DOI://10.1371/journal.pone.0151391 (2016)
Microscopic interpretation of folding φ-values using the transition path ensemble Robert B. Best and Gerhard Hummer PNAS, doi: 10.1073/pnas.1520864113 (2016)
Structural insights of a PI3K/mTOR dual inhibitor with the morpholino-triazine scaffold Takako Takeda, Yanli Wang , Stephen H. Bryant J. Computer-Aided Molecular Design, doi://10.1007/s10822-016-9905-4 (2016)
Modulation of Folding Internal Friction by Local and Global Barrier Heights Wenwei Zheng, David de Sancho, and Robert B. Best J. Phys. Chem. Letters, DOI: 10.1021/acs.jpclett.6b00329 (2016)

The ISW1 and CHD1 ATP-dependent chromatin remodelers compete to set nucleosome spacing in vivo Josefina Ocampo, Razvan V. Chereji, Peter R. Eriksson and David J. Clark Nucleic Acids Research, doi://10.1093/nar/gkw068 (2016)
Biointeractions of ultrasmall glutathione-coated gold nanoparticles: effect of small size variations Alioscka A. Sousa, Sergio A. Hassan, Luiza L. Knittel, Andrea Balbo, Maria A. Aronova, Patrick H. Brown, Peter Schuck and Richard D. Leapman Nanoscale, DOI: 10.1039/C5NR07642K (2016)
The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes Rinschen, MM; Bharill, P; Wu, X et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddw016 (2016)
Mucolipidosis types II and III and non-syndromic stuttering are associated with different variants in the same genes Raza, MH; Domingues, CE; Webster, R et al. Eur. J. Hum. Genet., DOI://10.1038/ejhg.2015.154 (2016)
The Use of Minimal RNA Toeholds to Trigger the Activation of Multiple Functionalities Afonin, KA; Viard, M; Tedbury, P et al. Nano Lett., DOI://10.1021/acs.nanolett.5b04676 (2016)
Deep Convolutional Neural Networks for Computer-Aided Detection: CNN Architectures, Dataset Characteristics and Transfer Learning Hoo-Chang Shin Holger R. Roth ; Mingchen Gao ; Le Lu ; Ziyue Xu ; Isabella Nogues ; Jianhua Yao ; Daniel Mollura ; Ronald M. Summers IEEE Transactions on Medical Imaging, OI 10.1109/TMI.2016.2528162 (2016)

Preterm birth and air pollution: Critical windows of exposure for women with asthma Pauline Mendola, Maeve Wallace, Beom Seuk Hwang, Danping Liu, Candace Robledo, Tuija Mӓnnistö, Rajeshwari Sundaram, Seth Sherman, Qi Ying, Katherine L. Grantz J. Allergy Clin. Immunology, doi:10.1016/j.jaci.2015.12.1309 (2016)
Necdin is a breast cancer metastasis suppressor that regulates the transcription of c-Myc Minnkyong Lee, Sarah M. Beggs, Derek Gildea, Sujata Bupp, Jens Lichtenberg, Niraj S. Trivedi, NISC Comparative Sequencing Program, Ying Hu, David M. Bodine, and Nigel P.S. Crawford1 Oncotarget, doi: 10.18632/oncotarget.5230 (2016)
Genome-wide footprinting: ready for prime time? Myong-Hee Sung, Songjoon Baek & Gordon L Hager Nature Methods, doi:10.1038/nmeth.3766 (2016)
A Comparison of Methods to Reweight from Classical Molecular Simulations to QM/MM Potentials Eric Christopher Dybeck, Gerhard König, Bernard R. Brooks, and Michael R. Shirts J. Chem. Theory. Comput, DOI: 10.1021/acs.jctc.5b01188 (2016)
Multistrand Structure Prediction of Nucleic Acid Assemblies and Design of RNA Switches Eckart Bindewald, Kirill A. Afonin, Mathias Viard, Paul Zakrevsky, Taejin Kim, and Bruce A. Shapiro Nano Letters, DOI: 10.1021/acs.nanolett.5b04651 (2016)
Understanding the Mechanism of the Hydrogen Abstraction from Arachidonic Acid Catalyzed by the Human Enzyme 15-Lipoxygenase-2. A Quantum Mechanics/Molecular Mechanics Free Energy Simulation Reynier Suardiaz, Pablo Garcia Jambrina, Laura Masgrau, Ángels Gonzàlez-Lafont, Edina Rosta, and Josè M. Lluch J. Chem. Theory. Comput, DOI: 10.1021/acs.jctc.5b01236 (2016)

Impact of time-of-day on brain morphometric measures derived from T₁-weighted magnetic resonance imaging Aaron Trefler, Neda Sadeghi, Adam G. Thomas, Carlo Pierpaoli, Chris I. Baker, Cibu Thomas Neuroimage, doi:10.1016/j.neuroimage.2016.02.034 (2016)
Enhancer of Rudimentary Cooperates with Conserved RNA-Processing Factors to Promote Meiotic mRNA Decay and Facultative Heterochromatin Assembly Sugiyama, T; Thillainadesan, G; Chalamcharla, VR et al. Mol. Cell, DOI://10.1016/j.molcel.2016.01.029 (2016)
Production of small cysteine-rich effector proteins in Escherichia coli for structural and functional studies Xiaoxiao Zhang, Neal Nguyen, Susan Breen, Megan A. Outram, Peter N. Dodds, Bostjan Kobe, Peter S. Solomon and Simon J. Williams Molecular Plant Pathology, DOI: 10.1111/mpp.12385 (2016)
Deubiquitylation of protein cargo is not an essential step in exosome formation Alyssa R. Huebner, Lei Cheng, Poorichaya Somparn, Mark A. Knepper, Robert A. Fenton and Trairak Pisitkun Molecular and Cellular Proteomics, doi: 10.1074/mcp.M115.054965 (2016)
A Helitron transposon reconstructed from bats reveals a novel mechanism of genome shuffling in eukaryotes Grabundzija, I; Messing, SA; Thomas, J et al. Nat Commun, DOI://10.1038/ncomms10716 (2016)
Mechanism of Protein Molecule Isolation by IR Laser Ablation of Droplet Beam Kensuke Komatsu, Takuya Nirasawa, Mariko Hoshino-Nagasaka, and Jun-ya Kohno J. Phys. Chem. A, DOI: 10.1021/acs.jpca.5b10873 (2016)

A genome landscape of SRSF3-regulated splicing events and gene expression in human osteosarcoma U2OS cells Ajiro M, Jia R, Yang Y, Zhu J, Zheng ZM Nucleic Acids Res., DOI://10.1093/nar/gkv1500 (2016)
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients Alena Gros, Maria R Parkhurst, Eric Tran, Anna Pasetto, Paul F Robbins, Sadia Ilyas, Todd D Prickett, Jared J Gartner, Jessica S Crystal, Ilana M Roberts, Kasia Trebska-McGowan, John R Wunderlich, James C Yang & Steven A Rosenberg Nature Medicine, doi:10.1038/nm.4051 (2016)
Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts Liang Ma, Zehua Chen, Da Wei Huang et. al. Nature Communications, doi:10.1038/ncomms10740 (2016)
Gene-Based Association Analysis for Censored Traits Via Fixed Effect Functional Regressions. Fan R, Wang Y, Yan Q, Ding Y, Weeks DE, Lu Z, Ren H, Cook RJ, Xiong M, Swaroop A, Chew EY, Chen W Genet Epidemiol. , doi: 10.1002/gepi.21947 (2016)
Finite sample pointwise confidence intervals for a survival distribution with right-censored data Michael P. Fay and Erica H. Brittain Statistics in Medicine, DOI: 10.1002/sim.6905 (2016)
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept Franke, B; Stein, JL; Ripke, S et al. Nat. Neurosci., DOI://10.1038/nn.4228 (2016)

High-throughput single-molecule screen for small-molecule perturbation of splicing and transcription kinetics Day CR, Chen H, Coulon A, Meier JL, Larson DR, Methods, DOI://10.1016/j.ymeth.2015.11.025 (2016)
Resolving the Complexity of Human Skin Metagenomes Using Single-Molecule Sequencing Yu-Chih Tsai, Sean Conlan, Clayton Deming, NISC Comparative Sequencing Program, Julia A. Segre, Heidi H. Kong Jonas Korlach, and Julia Oh mBio, doi: 10.1128/mBio.01948-15 (2016)
Recessive mutations of TMC1 associated with moderate to severe hearing loss Ayesha Imtiaz , Azra Maqsood , Atteeq U. Rehman, Robert J. Morell, Jeffrey R. Holt, Thomas B. Friedman, Sadaf Naz Neurogenetics, DOI 10.1007/s10048-016-0477-1 (2016)
Light-regulated Molecular Trafficking in a Synthetic Water-soluble Host Jesús del Barrio, Sean T. J. Ryan, Pablo G. Jambrina, Edina Rosta, and Oren A Scherman JACS, DOI: 10.1021/jacs.5b11642 (2016)
Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating Doreen Matthies, Olivier Dalmas, Mario J. Borgnia, Pawel K. Dominik, Alan Merk, Prashant Rao, Bharat G. Reddy, Shahidul Islam, Alberto Bartesaghi, Eduardo Perozo, Sriram Subramaniam Cell, doi:10.1016/j.cell.2015.12.055 (2016)
Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin Chanhyung Bae, Claudio Anselmi, Jeet Kalia, Andres Jara-Oseguera, Charles D Schwieters, Dmitriy Krepkiy ,Chul Won Lee, Eun-Hee Kim, Jae Il Kim, Josè D Faraldo-Gòmez and Kenton J Swartz eLife, DOI: http://dx.doi.org/10.7554/eLife.11273 (2016)

Self-aggregation and coaggregation of the p53 core fragment with its aggregation gatekeeper variant Jiangtao Lei , Ruxi Qi , Guanghong Wei , Ruth Nussinov and Buyong Ma Phys. Chem. Chem. Phys., DOI: 10.1039/C5CP06538K (2016)
Cutting Edge: Expression of IRF8 in Gastric Epithelial Cells Confers Protective Innate Immunity against Helicobacter pylori Infection Yan, M; Wang, H; Sun, J et al. J. Immunol., DOI://10.4049/jimmunol.1500766 (2016)
Genome-Wide Chromatin Landscape Transitions Identify Novel Pathways in Early Commitment to Osteoblast Differentiation Thompson B, Varticovski L, Baek S, Hager GL PLoS ONE, DOI://10.1371/journal.pone.0148619 (2016)
Drug repurposing to target Ebola virus replication and virulence using structural systems pharmacology Zhao Z, Martin C, Fan R, Bourne PE, Xie L BMC Bioinformatics, DOI://10.1186/s12859-016-0941-9 (2016)
Vibratory Urticaria Associated with a Missense Variant in ADGRE2 Boyden, SE; Desai, A; Cruse, G et al. N. Engl. J. Med., DOI://10.1056/NEJMoa1500611 (2016)
Identifying subgroups of enhanced predictive accuracy from longitudinal biomarker data by using tree-based approaches: applications to fetal growth Jared C. Foster, Danping Liu, Paul S. Albert and Aiyi Liu Journal of the Royal Statistical Society: Series A (Statisti, 10.1111/rssa.12182 (2016)

How Does Hyperphopsphorylation Promote Tau Aggregation and Modulate Filament Structure and Stability? Liang Xu, Jie Zheng, Martin Margittai, Ruth Nussinov, and Buyong Ma ACS Chemical Neuroscience, 10.1021/acschemneuro.5b00294 (2016)
In vivo tissue has non-linear rheological behavior distinct from 3D biomimetic hydrogels, as determined by AMOTIV microscopy Blehm BH, Devine A, Staunton JR, Tanner K Biomaterials, DOI://10.1016/j.biomaterials.2015.12.019 (2016)
Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium van den Berg, SM; de Moor, MH; Verweij, KJ et al. Behav. Genet., DOI://10.1007/s10519-015-9735-5 (2016)
Draft Genome Sequence of a Klebsiella pneumoniae Carbapenemase-Positive Sequence Type 111 Pseudomonas aeruginosa Strain Dotson GA, , Dekker JP, Palmore TN, Segre JA, Conlan S Genome Announc, DOI://10.1128/genomeA.01663-15 (2016)
The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1 Dell'Orso, S; Wang, AH; Shih, HY et al. Cell Rep, 2211-1247 (2016)
Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice Davies, B; Hatton, E; Altemose, N et al. Nature, DOI://10.1038/nature16931 (2016)

r2VIM: A new variable selection method for random forests in genome-wide association studies Silke Szymczak, Emily Holzinger, Abhijit Dasgupta, James D. Malley, Anne M. Molloy, James L. Mills, Lawrence C. Brody, Dwight Stambolian and Joan E. Bailey-Wilson BioData Mining, 10.1186/s13040-016-0087-3 (2016)
Identification of Microorganisms by High Resolution Tandem Mass Spectrometry with Accurate Statistical Significance Gelio Alves, Guanghui Wang, Aleksey Y. Ogurtsov, Steven K. Drake, Marjan Gucek, Anthony F. Suffredini, David B. Sacks, Yi-Kuo Yu J Am Soc Mass Spectrom 27:194-210, 10.1007/s13361-015-1271-2 (2016)
CircInteractome: A web tool for exploring circular RNAs and their interacting proteins and microRNAs Dudekula, DB; Panda, AC; Grammatikakis, I; De, S; Abdelmohsen, K; Gorospe, M; RNA Biol, DOI://10.1080/15476286.2015.1128065 (2016)
Somatic mutational landscape of AML with inv(16) or t(8;21) identifies patterns of clonal evolution in relapse leukemia Sood, R; Hansen, NF; Donovan, FX et al. Leukemia, DOI://10.1038/leu.2015.141 (2016)
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function Pattaro, C; Teumer, A; Gorski, M et al. Nat Commun, DOI://10.1038/ncomms10023 (2016)
Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium Ma, Y; Follis, JL; Smith, CE et al. Am. J. Clin. Nutr., DOI://10.3945/ajcn.115.112987 (2016)

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk Lu, Y; Day, FR; Gustafsson, S et al. Nat Commun, DOI://10.1038/ncomms10495 (2016)
Is the MC1R variant p. R160W associated with Parkinson's? Lubbe, SJ; Escott-Price, V; Brice, A et al. Ann. Neurol., DOI://10.1002/ana.24527 (2016)
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels Kilpeläinen, TO; Carli, JF; Skowronski, AA et al. Nat Commun, DOI://10.1038/ncomms10494 (2016)
Comparison of the Conformations of KRAS Isoforms, K-Ras4A and K-Ras4B, Points to Similarities and Significant Differences Mayukh Chakrabarti, Hyunbum Jang, and Ruth Nussinov J. Phys. Chem. B, DOI: 10.1021/acs.jpcb.5b11110 (2016)
Risk of End-stage Renal Disease in Patients with Lupus Nephritis, 1970 to 2015 A systematic review and Bayesian meta-analysis Maria G. Tektonidou, Abhijit Dasgupta and Michael M. Ward Arthritis and Rheumatology, DOI: 10.1002/art.39594 (2016)
Coupling of the Non-Amyloid-Component (NAC) Domain and the KTK(E/Q)GV Repeats Stabilize the α-Synuclein Fibrils Liang Xu, Ruth Nussinov, Buyong Ma Eur. J. Med. Chem. , doi:10.1016/j.ejmech.2016.01.044 (2016)

Novel nucleosomal particles containing core histones and linker DNA but no histone H1 Cole, HA; Cui, F; Ocampo, J et al. Nucleic Acids Res., DOI://10.1093/nar/gkv943 (2016)
Role of the D1-D2 Linker of Human VCP/p97 in the Asymmetry and ATPase Activity of the D1-domain Tang WK, Xia D Sci Rep, DOI://10.1038/srep20037 (2016)
Epigenetic regulation of hematopoiesis by DNA methylation Gore, AV; Athans, B; Iben, JR et al. Elife, DOI://10.7554/eLife.11813 (2016)
The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl Dine, JL; O'Sullivan, CC; Voeller, D et al. Breast Cancer Res. Treat., DOI://10.1007/s10549-015-3673-z (2016)
Post-transcriptional Control of Tumor Cell Autonomous Metastatic Potential by CCR4-NOT Deadenylase CNOT7 Faraji, F; Hu, Y; Yang, HH et al. PLoS Genet., DOI://10.1371/journal.pgen.1005820 (2016)
Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study Liping Hou, Urs Heilbronner et al. Lancet, doi:10.1016/S0140-6736(16)00143-4 (2016)

Autosomal-Recessive Hearing Impairment due to Rare Missense Variants within S1PR2 Regie Lyn P. Santos-Cortez, Rabia Faridi, Atteeq U. Rehman et al. American Journal of Human Genetics, doi://10.1016/j.ajhg.2015.12.004 (2016)
Nanopore Sequencing as a Rapidly Deployable Ebola Outbreak Tool Thomas Hoenen, Allison Groseth, Kyle Rosenke et al. Emerging Infectious Diseases, doi: 10.3201/eid2202.151796. (2016)
Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment Zhong, C; Cui, K; Wilhelm, C et al. Nat. Immunol., DOI://10.1038/ni.3318 (2016)
Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for Cellular Therapy Sukumar, M; Liu, J; Mehta, GU et al. Cell Metab., DOI://10.1016/j.cmet.2015.11.002 (2016)
Reliability of 7T (1) H-MRS measured human prefrontal cortex glutamate, glutamine, and glutathione signals using an adapted echo time optimized PRESS sequence: A between- and within-sessions investigation Lally, N; An, L; Banerjee, D et al. J Magn Reson Imaging, DOI://10.1002/jmri.24970 (2016)
A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration de Vries, PS; Chasman, DI; Sabater-Lleal, M et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddv454 (2016)

PubChem Substance and Compound databases Kim, S; Thiessen, PA; Bolton, EE et al. Nucleic Acids Res., DOI://10.1093/nar/gkv951 (2016)
Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes Lorenzi, H; Khan, A; Behnke, MS et al. Nat Commun, DOI://10.1038/ncomms10147 (2016)
SBR-Blood: systems biology repository for hematopoietic cells Lichtenberg, J; Heuston, EF; Mishra, T; Keller, CA; Hardison, RC; Bodine, DM; Nucleic Acids Res., DOI://10.1093/nar/gkv1263 (2016)
GABBR1 and SLC6A1, Two Genes Involved in Modulation of GABA Synaptic Transmission, Influence Risk for Alcoholism: Results from Three Ethnically Diverse Populations Enoch, MA; Hodgkinson, CA; Shen, PH et al. Alcohol. Clin. Exp. Res., DOI://10.1111/acer.12929 (2016)
SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery Saxena, N; Maio, N; Crooks, DR et al. J. Natl. Cancer Inst., DOI://10.1093/jnci/djv287 (2016)
Evolutionary Dynamics of Influenza A Viruses in US Exhibition Swine Nelson, MI; Wentworth, DE; Das, SR et al. J. Infect. Dis., DOI://10.1093/infdis/jiv399 (2016)

2015 (340 papers)

miR-501-3p mediates the activity-dependent regulation of the expression of AMPA receptor subunit GluA1 Hu, Z; Zhao, J; Hu, T; Luo, Y; Zhu, J; Li, Z; J. Cell Biol., DOI://10.1083/jcb.201404092 (2015)
Bayesian dose-response analysis for epidemiological studies with complex uncertainty in dose estimation Deukwoo Kwon, F. Owen Hoffman, Brian E. Moroz, Steven L. Simon Statistics in Medicine, DOI: 10.1002/sim.6635 (2015)
Augmented trial designs for evaluation of principal surrogates Erin E. Gabriel and Dean Follmann Biostatistics, 10.1093/biostatistics/kxv055 (2015)
Dimerization of the SP1 Region of HIV-1 Gag Induces a Helical Conformation and Association into Helical Bundles: Implications for Particle Assembly Datta, SA; Clark, PK; Fan, L et al. J. Virol., DOI://10.1128/JVI.02061-15 (2015)
Multivariate classification of smokers and nonsmokers using SVM-RFE on structural MRI images Ding X, Yang Y, Stein EA, Ross TJ Hum Brain Mapp, DOI://10.1002/hbm.22956 (2015)
The higher level of complexity of K-Ras4B activation at the membrane Hyunbum Jang, Avik Banerjee, Tanmay S. Chavan, Shaoyong Lu, Jian Zhang, Vadim Gaponenko and Ruth Nussinov FASEB J. , doi: 10.1096/fj.15-279091 (2015)

Mixed group of Rhizobiales microbes in lung and blood of a patient with fatal pulmonary illness Shyh-Ching Lo, Guo-Chiuan Hung, Bing jie Li, Haiyan Lei, Tianwei Li, Kenjiro Nagamine, Shien Tsai, Mark J Zucker, Ludmilla Olesnicky Int J Clin Exp Patho, 8(11), 13834-13852. (2015)
Meta-analysis of Complex Diseases at Gene Level by Generalized Functional Linear Models Ruzong Fan, Yifan Wang, Chi-yang Chiu, Wei Chen, Haobo Ren, Yun Li, Michael Boehnke, Christopher I. Amos, Jason H. Moore, Momiao Xiong Genetics, DOI: 10.1534/genetics.115.180869 (2015)
TET-catalyzed oxidation of intragenic 5-methylcytosine regulates CTCF-dependent alternative splicing Ryan J Marina, David Sturgill, Marc A Bailly, Morgan Thenoz, Garima Varma, Maria F Prigge, Kyster K Nanan, Sanjeev Shukla, Nazmul Haque, Shalini Oberdoerffer EMBO J., DOI 10.15252/embj.201593235 (2015)
RNA Polymerase III Output Is Functionally Linked to tRNA Dimethyl-G26 Modification Arimbasseri, AG; Blewett, NH; Iben, JR et al. PLoS Genet., DOI://10.1371/journal.pgen.1005671 (2015)
Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design Jason Gorman, Cinque Soto, Max M Yang, et al. Nature Structural and Molecular Biology, doi:10.1038/nsmb.3144 (2015)
ADAR2 affects mRNA coding sequence edits with only modest effects on gene expression or splicing in vivo Allissa A. Dillman, Mark R. Cookson & Dagmar Galter RNA Biology, DOI://10.1080/15476286.2015.1110675 (2015)

Controlled DNA double-strand break induction in mice reveals post-damage transcriptome stability Jeongkyu Kim, David Sturgill, Andy D. Tran, David A. Sinclair and Philipp Oberdoerffer Nucleic Acids Research, doi: 10.1093/nar/gkv1482 (2015)
Distributed acoustic cues for caller identity in macaque vocalization Makoto Fukushima, Alex M. Doyle, Matthew P. Mullarkey, Mortimer Mishkin, Bruno B. Averbeck Royal Society Open Science, DOI: 10.1098/rsos.150432 (2015)
Socioeconomic disadvantage and neural development from infancy through early childhood Chin-Lun Hung, G; Hahn, J; Alamiri, B et al. Int J Epidemiol, DOI://10.1093/ije/dyv303 (2015)
Directed and persistent movement arises from mechanochemistry of the ParA/ParB system Hu L, Vecchiarelli AG, Mizuuchi K, Neuman KC, Liu J Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1505147112 (2015)
Assessment of established HDL-C loci for association with HDL-C levels and type 2 diabetes in Pima Indians Anup K. Nair, Paolo Piaggi, Nellie A. McLean, Manmeet Kaur, Sayuko Kobes, William C. Knowler, Clifton Bogardus, Robert L. Hanson, Leslie J. Baier Diabetologia, doi://10.1007/s00125-015-3835-x (2015)
Genome-wide association study identifies African-ancestry specific variants for metabolic syndrome Tekola-Ayele, F; Doumatey, AP; Shriner, D et al. Mol. Genet. Metab., DOI://10.1016/j.ymgme.2015.10.008 (2015)

Evolutionary context for the association of γ-globin, serum uric acid, and hypertension in African Americans Shriner, D; Kumkhaek, C; Doumatey, AP et al. BMC Med. Genet., DOI://10.1186/s12881-015-0249-z (2015)
High-Affinity Interaction of the K-Ras4B Hypervariable Region with the Ras Active Site Tanmay S. Chavan, Hyunbum Jang, Lyuba Khavrutskii, Sherwin J. Abraham, Avik Banerjee, Benjamin C. Freed, Liv Johannessen, Sergey G. Tarasov, Vadim Gaponenko, Ruth Nussinov4, Nadya I. Tarasova Biophys. J. , doi:10.1016/j.bpj.2015.09.034 (2015)
Coupling between histone conformations and DNA geometry in nucleosomes on a microsecond timescale: atomistic insights into nucleosome functions Alexey K. Shaytan, Grigoriy A. Armeev, Alexander Goncearenco, Victor B. Zhurkin, David Landsman, Anna R. Panchenko J. Mol. Biol., doi:10.1016/j.jmb.2015.12.004 (2015)
Drug-Protein Hydrogen Bonds Govern the Inhibition of the ATP Hydrolysis of the Multidrug Transporter P-glycoprotein Eduardo E. Chufan, Khyati Kapoor, Suresh V. Ambudkar Biochemical Pharmacology, doi:10.1016/j.bcp.2015.12.007 (2015)
MYCN controls an alternative RNA splicing program in high-risk metastatic neuroblastoma Shile Zhang, Jun S. Wei1 , Samuel Q. Li , Tom C. Badgett , Young K. Song , Saurabh Agarwal , Cristian Coarfa , Catherine Tolman , Laura Hurd , Hongling Liao , Jianbin He , Xinyu Wen , Zhihui Liu , Carol J. Thiele , Frank Westermann , Shahab Asgharzadeh , Robert C. Seeger , John M. Maris , Jamie M. Guidry Auvil , Malcolm A. Smith , Eric D. Kolaczyk , Jason Shohet , Javed Khan Cancer Letters, doi://10.1016/j.canlet.2015.11.045 (2015)
Multi-modal characterization of rapid anterior hippocampal volume increase associated with aerobic exercise Adam G. Thomas, Andrea Dennis, Nancy B. Rawlings, Charlotte J. Stagg, Lucy Matthews, Martyn Morris, Shannon H. Kolind, Sean Foxley, Mark Jenkinson, Thomas E. Nichols, Helen Dawes, Peter A. Bandettini, Heidi Johansen-Berg NeuroImage, doi:10.1016/j.neuroimage.2015.10.090 (2015)

Allosteric stabilization of the amyloid-β peptide hairpin by the fluctuating N-terminal Liang Xu , Ruth Nussinov and Buyong Ma Chem. Commun., DOI: 10.1039/C5CC08107F (2015)
Intrinsic excitability measures track antiepileptic drug action and uncover increasing/decreasing excitability over the wake/sleep cycle Christian Meisel, Andreas Schulze-Bonhage, Dean Freestone, Mark James Cook, Peter Achermann, Dietmar Plenz PNAS, doi: 10.1073/pnas.1513716112 (2015)
Transcriptional and Chromatin Regulation during Fasting - The Genomic Era Goldstein I, Hager GL Trends Endocrinol. Metab., DOI://10.1016/j.tem.2015.09.005 (2015)
Evaluation of Genome Wide Association Study Associated Type 2 Diabetes Susceptibility Loci in Sub Saharan Africans Adeyemo, AA; Tekola-Ayele, F; Doumatey, AP et al. Front Genet, DOI://10.3389/fgene.2015.00335 (2015)
Genome Sequence of the Banana Plant Growth-Promoting Rhizobacterium Bacillus amyloliquefaciens BS006 Rocío M. Gamez, Fernando Rodríguez, Johan F. Bernal, Richa Agarwala, David Landsman, Leonardo Mariño-Ramírez Genome Announc., doi: 10.1128/genomeA.01391-15 (2015)
HIV Therapeutics and Methods of Making and Using Same Paolo Lusso and Raffaelo Cimbro Patent, United States Patent Application 20150313990 (2015)

NCICT: a computational solution to estimate organ doses for pediatric and adult patients undergoing CT scans Choonsik Lee, Kwang Pyo Kim, Wesley E Bolch, Brian E Moroz and Les Folio J. Radiological Protection, doi:10.1088/0952-4746/35/4/891 (2015)
Reduction of All-Atom Protein Folding Dynamics to One-Dimensional Diffusion Wenwei Zheng and Robert B. Best J. Phys. Chem. , DOI: 10.1021/acs.jpcb.5b09741 (2015)
Transient misfolding dominates multidomain protein folding Alessandro Borgia, Katherine R. Kemplen, Madeleine B. Borgia, Andrea Soranno, Sarah Shammas, Bengt Wunderlich, Daniel Nettels, Robert B. Best, Jane Clarke & Benjamin Schuler Nature Communications, doi:10.1038/ncomms9861 (2015)
Replicate exome-sequencing in a multiple-generation family: improved interpretation of next-generation sequencing data Praveen F. Cherukuri, Valerie Maduro, Karin V. Fuentes-Fajardo, Kevin Lam, David R. Adams, Cynthia J. Tifft, James C. Mullikin, William A. Gahl, Cornelius F. Boerkoel and NISC Comparative Sequencing Program BMC Genomics, doi:10.1186/s12864-015-2107-y (2015)
HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis Michael J. Ombrello, Elaine F. Remmers, Ioanna Tachmazidou et al and the International Childhood Arthritis Genetics (INCHARGE) Consortium PNAS, doi: 10.1073/pnas.1520779112 (2015)
Estimation of interaction effects using pooled biospecimens in a case-control study Michelle R. Danaher, Paul S. Albert, Aninyda Roy and Enrique F. Schisterman Statistics in Medicine, DOI: 10.1002/sim.6798 (2015)

Epstein-Barr virus from Burkitt Lymphoma biopsies from Africa and South America share novel LMP-1 promoter and gene variations Lei H, Li T, Li B, Tsai S, Biggar RJ, Nkrumah F, Neequaye J, Gutierrez M, Epelman S, Mbulaiteye SM, Bhatia K, Lo SC Sci Rep., doi: 10.1038/srep16706 (2015)
A 3D Searchable Database of Transgenic Zebrafish Gal4 and Cre Lines for Functional Neuroanatomy Studies Gregory D. Marquart, Kathryn M. Tabor, Mary Brown, Jennifer L. Strykowski, Gaurav K. Varshney, Matthew C. LaFave, Thomas Mueller, Shawn M. Burgess, Shin-ichi Higashijima and Harold A. Burgess Frontiers in Neural Circuits, doi://10.3389/fncir.2015.00078 (2015)
GTP Binding and Oncogenic Mutations May Attenuate Hypervariable Region (HVR)-Catalytic Domain Interactions in Small GTPase K-Ras4B, Exposing the Effector Binding Site Lu S, Banerjee A, Jang H, Zhang J, Gaponenko V, Nussinov R J. Biol. Chem., DOI://10.1074/jbc.M115.664755 (2015)
A Novel MHC-I Surface Targeted for Binding by the MCMV m06 Immunoevasin Revealed by Solution NMR Sgourakis NG, May NA, Boyd LF, Ying J, Bax A, Margulies DH J. Biol. Chem., DOI://10.1074/jbc.M115.689661 (2015)
Epidermal devices for noninvasive, precise, and continuous mapping of macrovascular and microvascular blood flow Webb, RC; Ma, Y; Krishnan, S et al. Sci Adv, DOI://10.1126/sciadv.1500701 (2015)
Clinical feasibility of using mean apparent propagator (MAP) MRI to characterize brain tissue microstructure Alexandru V. Avram, Joelle E. Sarlls, Alan S. Barnett, Evren Özarslan, Cibu Thomas, M. Okan Irfanoglu, Elizabeth Hutchinson, Carlo Pierpaoli, Peter J. Basser NeuroImage, doi:10.1016/j.neuroimage.2015.11.027 (2015)

Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma Bogen, D; Wei, JS; Azorsa, DO et al. Oncotarget, DOI://10.18632/oncotarget.6208 (2015)
Phenotypic variance explained by local ancestry in admixed African Americans Shriner, D; Bentley, AR; Doumatey, AP et al. Front Genet, DOI://10.3389/fgene.2015.00324 (2015)
Distribution and evolution of the serine/aspartate racemase family in invertebrates Kouji Uda, Keita Abe, Yoko Dehara, Kiriko Mizobata, Natsumi Sogawa, Yuki Akagi, Mai Saigan, Atanas D. Radkov, Luke A. Moe Amino Acids, doi://10.1007/s00726-015-2092-0 (2015)
Selectivity in the Use of Gi/o Proteins Is Determined by the DRF Motif in CXCR6 and Is Cell-Type Specific Satya P. Singh, John F. Foley, Hongwei H. Zhang, Darrell E. Hurt, Jennifer L. Richards, Craig S. Smith, Fang Liao, and Joshua M. Farber Molecular Pharmacology, doi: 10.1124/mol.115.099960 (2015)
The Structural Basis of Actin Organization by Vinculin and Metavinculin Laura Y. Kim, Peter M. Thompson, Hyunna T. Lee, Mihir Pershad, Sharon L. Campbell, Gregory M. Alushin J. Mol. Biol. , doi:10.1016/j.jmb.2015.09.031 (2015)
Analysis of SLC16A11 variants in 12,811 American Indians: genotype-obesity interaction for type 2 diabetes and an association with RNASEK expression Michael Traurig, Robert L. Hanson, Alejandra Marinelarena, Sayuko Kobes, Paolo Piaggi, Shelley Cole, Joanne E. Curran, John Blangero, Harald Göring, Satish Kumar, Robert G. Nelson, Barbara V. Howard, William C. Knowler, Leslie J. Baier and Clifton Bogardus Diabetes, doi: 10.2337/db15-0571 (2015)

In Search of a Cure for Proteostasis-Addicted Cancer: A AAA Target Revealed Xia D, Ye Y Cancer Cell, DOI://10.1016/j.ccell.2015.10.006 (2015)
Genome-wide estimate of the heritability of Multiple System Atrophy M. Federoff, T.R. Price, A. Sailer, S. Scholz, D. Hernandez, A. Nicolas, A.B. Singleton, M. Nalls, H. Houlden Parkinsonism and Related Disorders, doi:10.1016/j.parkreldis.2015.11.005 (2015)
Reprogramming of Polycomb-Mediated Gene Silencing in Embryonic Stem Cells by the miR-290 Family and the Methyltransferase Ash1l Chryssa Kanellopoulou, Timothy Gilpatrick, Gokhul Kilaru, Patrick Burr, Cuong K. Nguyen, Aaron Morawski, Michael J. Lenardo, Stefan A. Muljo Stem Cell Reports, doi:10.1016/j.stemcr.2015.10.001 (2015)
Resting-state functional connectivity and presynaptic monoamine signaling in Alcohol Dependence Zhu X, Dutta N, Helton SG, Schwandt M, Yan J, Hodgkinson CA, Cortes CR, Kerich M, Hall S, Sun H, Phillips M, Momenan R, Lohoff FW Hum Brain Mapp., doi: 10.1002/hbm.22951 (2015)
Effects of the C-Terminal Tail on the Conformational Dynamics of Human Neuronal Calcium Sensor-1 Protein Zhu, Y; Yang, S; Qi, R et al. J Phys Chem B, DOI://10.1021/acs.jpcb.5b07962 (2015)
ColoWeb: a resource for analysis of colocalization of genomic features Kim R, Smith OK, Wong WC, Ryan AM, Ryan MC, Aladjem MI BMC genomics, doi: 10.1186/s12864-015-1345-3. (2015)

Methylated cytosines mutate to transcription factor binding sites that drive tetrapod evolution Ximiao He, Desiree Tillo, Jeff Vierstra, Khund-Sayeed Syed, Callie Deng, Jordan G. Ray, John Stamatoyannopoulos, Peter C. Fitzgerald and Charles Vinson Genome Biol. and Evol. , doi: 10.1093/gbe/evv205 (2015)
Sequence-and Temperature-Dependent Properties of Unfolded and Disordered Proteins from Atomistic Simulations Gül H. Zerze, Robert B Best, and Jeetain Mittal J. Phys. Chem. B, DOI: 10.1021/acs.jpcb.5b08619 (2015)
Proteomic Profiling of Nuclear Fractions from Native Renal Inner Medullary Collecting Duct Cells Christina M. Pickering, Cameron R. Grady, Barbara Medvar, Milad Emamian, Pablo Concha Sandoval, Yue Zhao, Chin-Rang Yang, Hyun Jun Jung, Chung-Lin Chou, Mark A. Knepper Physiol Genomics., DOI: 10.1152/physiolgenomics.00090.2015 (2015)
Structure dependent hydrophobic and hydrophilic interactions between nickel(II) Schiff base complexes and serum albumins: Spectroscopic and docking studies Banabithi Koley Seth, Aurkie Ray, Mousumi Banerjee, Teerna Bhattacharyya, Dhananjay Bhattacharyya, Samita Basu J. Luminescence, doi:10.1016/j.jlumin.2015.11.009 (2015)
A Transcriptional Map of the Renal Tubule: Linking Structure to Function Kretzler, M; Ju, W; J. Am. Soc. Nephrol., DOI://10.1681/ASN.2015030242 (2015)
Integrated genome-wide analysis of genomic changes and gene regulation in human adrenocortical tissue samples Gara, SK; Wang, Y; Patel, D et al. Nucleic Acids Res., DOI://10.1093/nar/gkv908 (2015)
Cell Migration and Invadopodia Formation Require a Membrane-binding Domain of CARMIL2 M. Hunter Lanier, Patrick McConnell and John A. Cooper J. Biol. Chem. , doi: 10.1074/jbc.M115.676882 (2015)
An insight into the sialome of the horse fly, Tabanus bromius Ribeiro JM, Kazimirova M, Takac P, Andersen JF, Francischetti IM Insect Biochem. Mol. Biol., DOI://10.1016/j.ibmb.2015.09.002 (2015)
TCF21 hypermethylation in genetically quiescent clear cell sarcoma of the kidney Saskia L. Gooskens, Samantha Gadd, Jaime M. Guidry Auvil, Daniela S. Gerhard, Javed Khan, Rajesh Patidar, Daoud Meerzaman, Qing-Rong Chen, Chih Hao Hsu, Chunhua Yan, Cu Nguyen, Ying Hu, Charles G. Mullighan, Jing Ma, Lawrence J. Jennings, Ronald R. de Krijger, Marry M. van den Heuvel-Eibrink, Malcolm A. Smith, Nicole Ross, Julie M. Gastier-Foster, Elizabeth J. Perlman Oncotarget 6(18):15828-15841 (2015)
Molecular mechanisms in genetically defined autoinflammatory diseases: disorders of amplified danger signaling de Jesus AA, Canna SW, Liu Y, Goldbach-Mansky R. Annu Rev Immunol., doi: 10.1146/annurev-immunol-032414-112227 (2015)
Functional connectivity classification of autism identifies highly predictive brain features but falls short of biomarker standards Plitt M, Barnes KA, Martin A Neuroimage Clin., doi: 10.1016/j.nicl.2014.12.013. (2015)
Effects of the Mu opioid receptor polymorphism (OPRM1 A118G) on pain regulation, placebo effects and associated personality trait measures Peciña M, Love T, Stohler CS, Goldman D, Zubieta JK Neuropsychopharmacology, doi: 10.1038/npp.2014.272 (2015)

Calculation of Organ Doses for a Large Number of Patients Undergoing CT Examinations Amir Bahadori, Diana Miglioretti, Randell Kruger, Michael Flynn, Sheila Weinmann, Rebecca Smith-Bindman and Choonsik Lee Medical Physics and Informatics, DOI:10.2214/AJR.14.14135 (2015)
Survival of human lymphoma cells requires B-cell receptor engagement by self-antigens Ryan M. Young, Tianyi Wu, Roland Schmitz, Moez Dawood, Wenming Xiao, James D. Phelan, Weihong Xu, Laurence Menard, Eric Meffre, Wing-Chung C. Chan, Elaine S. Jaffe, Randy D. Gascoyne, Elìas Campo, Andreas Rosenwald, German Ott, Jan Delabie, Lisa M. Rimsza, and Louis M. Staudt PNAS, doi: 10.1073/pnas.1514944112 (2015)
Shifts in connectivity during procedural learning after motor cortex stimulation; a combined transcranial magnetic stimulation /functional magnetic resonance imaging study Adam Steel, Sunbin Song, Devin Bageac, Kristine M. Knutson, Ziad S. Saad, Stephen J. Gotts, Eric M. Wassermann, Leonora Wilkinson Cortex, doi:10.1016/j.cortex.2015.10.004 (2015)
Genome Sequences of Multidrug-Resistant Salmonella enterica Serovar Paratyphi B (dT+) and Heidelberg Strains from the Colombian Poultry Chain Pilar Donado-Godoy, Johan F. Bernal, Fernando Rodrìguez, Yolanda Gomez, Richa Agarwala, David Landsman, Leonardo Mariño-Ramìrez Genome Announc., doi: 10.1128/genomeA.01265-15 (2015)
The transcriptional landscape of age in human peripheral blood Peters, MJ; Joehanes, R; Pilling, LC et al. Nat Commun, DOI://10.1038/ncomms9570 (2015)
Empirical Optimization of Interactions between Proteins and Chemical Denaturants in Molecular Simulations Wenwei Zheng, Alessandro Borgia, Madeleine B. Borgia, Benjamin Schuler, and Robert B. Best J. Chem. Theory and Computation, DOI: 10.1021/acs.jctc.5b00778 (2015)

Characterization of the metastatic phenotype of a panel of established osteosarcoma cells Ren, L; Mendoza, A; Zhu, J et al. Oncotarget, DOI://10.18632/oncotarget.5177 (2015)
Computational Methods for Structural and Functional Studies of Alzheimer's Amyloid Ion Channels Hyunbum Jang, Fernando Teran Arce, Joon Lee, Alan L. Gillman, Srinivasan Ramachandran, Bruce L. Kagan, Ratnesh Lal, Ruth Nussinov Protein Amyloid Aggregation, doi://10.1007/978-1-4939-2978-8-16 (2015)
Single-cell RNA-Seq resolves cellular complexity in sensory organs from the neonatal inner ear Burns JC, Kelly MC, Hoa M, Morell RJ, Kelley MW Nature Communications, doi: 10.1038/ncomms9557. (2015)
Interleaved Text/Image Deep Mining on a Large-Scale Radiology Database for Automated Image Interpretation Hoo-Chang Shin, Le Lu, Lauren Kim, Ari Seff, Jianhua Yao, Ronald M. Summers IEEE CVPR , p. 1090-1099 (2015)
Longitudinal clinical trials with adaptive choice of follow-up time Jeffries N, Geller NL Biometrics, doi: 10.1111/biom.12287. E (2015)
Preparation and Crystallization of Riboswitches Alla Peselis, Ang Gao, Alexander Serganov Nucleic Acids Crystallography, doi://10.1007/978-1-4939-2763-0_3 (2015)

Effects of Neural Morphology and Input Distribution on Synaptic Processing by Global and Focal NMDA-Spikes Poleg-Polsky, A PLoS ONE, DOI://10.1371/journal.pone.0140254 (2015)
Dependence of negative-mode electrospray ionization response factors on mobile phase composition and molecular structure for newly-authenticated neutral acylsucrose metabolites Banibrata Ghosh and A. Daniel Jones Analyst, DOI: 10.1039/c4an02124j (2015)
Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumors Peter M. Moyle, Wei Dai, Tzu-Yu Liu, Waleed M. Hussein, Pirashanthini Maruthayanar, James W. Wells, Nigel A.J. McMillan, Mariusz Skwarczynski, Istvan Toth Bioorg. Med. Chem. Lett., doi:10.1016/j.bmcl.2015.10.049 (2015)
Establishment of Par-Polarized Cortical Domains via Phosphoregulated Membrane Motifs Matthew J. Bailey, Kenneth E. Prehoda Developmental Cell, doi://10.1016/j.devcel.2015.09.016 (2015)
Uncovering effects of antibiotics on the host and microbiota using transkingdom gene networks Morgun, A; Dzutsev, A; Dong, X et al. Gut, DOI://10.1136/gutjnl-2014-308820 (2015)
MST2-RASSF protein-protein interactions through SARAH domains Goar Sànchez-Sanz, David Matallanas, Lan K. Nguyen, Boris N. Kholodenko, Edina Rosta, Walter Kolch and Nicolae-Viorel Buchete Briefings in Bioinformatics, doi://10.1093/bib/bbv070 (2015)

Subassemblies and asymmetry in assembly of herpes simplex virus procapsid Aksyuk, AA; Newcomb, WW; Cheng, N et al. MBio, DOI://10.1128/mBio.01525-15 (2015)
GNL3 and SKA3 are novel prostate cancer metastasis susceptibility genes Minnkyong Lee, Kendra A. Williams, Ying Hu, Jonathan Andreas, Shashank J. Patel, Suiyuan Zhang, Nigel P. S. Crawford Clin Exp Metastasis, DOI 10.1007/s10585-015-9745-y (2015)
Putative Prostate Cancer Risk SNP in an Androgen Receptor-Binding Site of the Melanophilin Gene Illustrates Enrichment of Risk SNPs in Androgen Receptor Target Sites Huajie Bu, Narisu Narisu, Bettina Schlick, Johannes Rainer, Thomas Manke, Georg Schäfer, Lorenza Pasqualini, Peter Chines, Michal R. Schweiger, Christian Fuchsberger and Helmut Klocker Human Mutation, DOI: 10.1002/humu.22909 (2015)
Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity Hirahara K, Onodera A, Villarino AV, Bonelli M, Sciumè G, Laurence A3 Sun HW, Brooks SR, Vahedi, Shih HY, Gutierrez-Cruz, Iwata S, Suzuki, Mikami Y, Okamoto Y, Nakayama T, Holland SM, Hunter CA, Kanno Y, O'Shea JJ Immunity, doi: 10.1016/j.immuni.2015.04.014. (2015)
Efficient test for nonlinear dependence of two continuous variables Wang Y, Li Y, Cao H, Xiong M, Shugart YY, Jin L BMC Bioinformatics, doi: 10.1186/s12859-015-0697-7 (2015)
Whole-genome association analysis of treatment response in obsessive-compulsive disorder Qin H, Samuels JF, Wang Y et al. Mol. Psychiatr., doi: 10.1038/mp.2015.32 (2015)
The CENP-A N-tail confers epigenetic stability to centromeres via the CENP-T branch of the CCAN in fission yeast Folco HD, Campbell CS, May KM, Espinoza C, Oegema K, Hardwick KG, Grewal SI, Desai A Curr. Biology, doi: 10.1016/j.cub.2014.11.060 (2015)
RNA sequencing of the nephron transcriptome: A technical note Jae Wook Lee Kidney Research & Clinical Practice, doi:10.1016/j.krcp.2015.08.008 (2015)
Targeted Proteomics-Driven Computational Modeling of Macrophage S1P Chemosensing Manes, NP; Angermann, BR; Koppenol-Raab, M et al. Mol. Cell Proteomics, DOI://10.1074/mcp.M115.048918 (2015)
Genome-wide profiling of nucleosome sensitivity and chromatin accessibility in Drosophila melanogaster Razvan V. Chereji, Tsung-Wai Kan, Magda K. Grudniewska, Alexander V. Romashchenko, Eugene Berezikov, Igor F. Zhimulev, Victor Guryev, Alexandre V. Morozov and Yuri M. Moshkin Nucleic Acids Research, doi: 10.1093/nar/gkv978 (2015)
Identification of Scedosporium boydii catalase A1 gene, a reactive oxygen species detoxification factor highly expressed in response to oxidative stress and phagocytic cells Mina, Staerck et al Fungal Biology, doi:10.1016/j.funbio.2015.09.007 (2015)
Deep Proteomic Profiling of Vasopressin-Sensitive Collecting Duct Cells. II. Bioinformatic Analysis of Vasopressin Signaling Chin-Rang Yang, Viswanathan Raghuram, Milad Emamian, Pablo Concha Sandoval, Mark A. Knepper Am. J. Physiol. - Cell Physiol. , DOI: 10.1152/ajpcell.00214.2015 (2015)

Exposure of chick embryos to cadmium changes the extra-embryonic vascular branching pattern and alters expression of VEGF-A and VEGF-R2 Anna Kaskova Gheorghescu, Bartlomiej Tywoniuk, Johannes Duess, Nicolae-Viorel Buchete, Jennifer Thompson Toxicology & Applied Pharmacology, doi://10.1016/j.taap.2015.09.004 (2015)
Quantitative evaluation of positive φ angle propensity in flexible regions of proteins from three-bond J couplings Jung Ho Lee, Jinfa Ying and Ad Bax Phys. Chem. Chem. Phys., DOI: 10.1039/C5CP04542H (2015)
Turning Cucurbit[8]uril into a Supramolecular Nanoreactor for Asymmetric Catalysis Lifei Zheng, Silvia Sonzini, Masyitha Ambarwati, Edina Rosta, Oren A. Scherman and Andreas Herrmann Angewandte Chemie , DOI: 10.1002/anie.201505628 (2015)
Comparison against 186 canid whole-genome sequences reveals survival strategies of an ancient clonally transmissible canine tumor Brennan Decker, Brian W Davis, Maud Rimbault, Adrienne H Long, Eric Karlins, Heidi G Parker, Vidhya Jagannathan, Rebecca Reiman, Cord Drögemüller, Jason J Corneveaux, Erica S Chapman, Jeffery M Trent, Tosso Leeb, Matthew J Huentelman, Robert K Wayne, Danielle M Karyadi and Elaine A Ostrander Genome Research, doi: 10.1101/gr.190314.115 (2015)
Distinct profiles for mitochondrial t-RNAs and small nucleolar RNAs in locally invasive and metastatic colorectal cancer Lai Xu, Joseph Ziegelbauer, Rong Wang, Wells W Wu, Rong-Fong Shen, Hartmut H Juhl, Yaqin Zhang, and Amy S Rosenberg Clinical Cancer Research, doi: 10.1158/1078-0432.CCR-15-0737 (2015)
Plasma Levels of Soluble IL-2 Receptor α Associations With Clinical Cardiovascular Events and Genome-Wide Association Scan Peter Durda, Jeremy Sabourin, Ethan M. Lange, Mike A. Nalls, Josyf C. Mychaleckyj, Nancy Swords Jenny, Jin Li, Jeremy Walston, Tamara B. Harris, Bruce M. Psaty, William Valdar, Yongmei Liu, Mary Cushman, Alex P. Reiner, Russell P. Tracy, Leslie A. Lange Arteriosclerosis, Thrombosis and Vascular Biology, doi: 10.1161/ATVBAHA.115.305289 (2015)

Single Nucleotide Specific Targeting of the Tf1 Retrotransposon Promoted by the DNA-Binding Protein Sap1 of Schizosaccharomyces pombe Anthony Hickey, Caroline Esnault, Anasuya Majumdar, Atreyi Ghatak Chatterjee, James R. Iben, Philip G. McQueen, Andrew X. Yang, Takeshi Mizuguchi, Shiv I. S. Grewal and Henry L. Levin Genetics, doi: 10.1534/genetics.115.181602 (2015)
Pressure-induced structural transition of mature HIV-1 Protease from a combined NMR/MD simulation approach Julien Roche, John M. Louis, Ad Bax and Robert B. Best Proteins, DOI: 10.1002/prot.24931 (2015)
Histone H3 Lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiation Sugata Manna, Jong Kyong Kim, Catherine Baugé, Margaret Cam, Yongmei Zhao, Jyoti Shetty, Melanie S. Vacchio, Ehydel Castro, Bao Tran, Lino Tessarollo & Rémy Bosselut Nature Communications, doi:10.1038/ncomms9152 (2015)
Tautomerism of Warfarin: Combined Chemoinformatics, Quantum Chemical, and NMR Investigation Laura Guasch, Megan L. Peach, and Marc C Nicklaus J. Org. Chem. , DOI: 10.1021/acs.joc.5b01370 (2015)
Comparative analyses of CTCF and BORIS occupancies uncover two distinct classes of CTCF binding genomic regions Elena M. Pugacheva, Samuel Rivero-Hinojosa, Celso A. Espinoza, et al. Genome Biol. , doi: 10.1186/s13059-015-0736-8 (2015)
Triangulating the sexually dimorphic brain through high-resolution neuroimaging of murine sex chromosome aneuploidies Raznahan, A; Lue, Y; Probst, F et al. Brain Struct Funct, DOI://10.1007/s00429-014-0875-9 (2015)

TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow Yang, Q; Li, F; Harly, C et al. Nat. Immunol., DOI://10.1038/ni.3248 (2015)
Assessing FOXO1A as a potential susceptibility locus for type 2 diabetes and obesity in American Indians Yunhua L. Muller, Robert L. Hanson, Gregory Wiessner, Lori Nieboer, Sayuko Kobes, Paolo Piaggi, Mahdi Abdussamad, Chidinma Okani, William C. Knowler, Clifton Bogardus andLeslie J. Baier Obesity, DOI: 10.1002/oby.21236 (2015)
Correlation of magnetic resonance imaging with digital histopathology in prostate Jin Tae Kwak, Sandeep Sankineni, Sheng Xu, Baris Turkbey, Peter L. Choyke, Peter A. Pinto, Maria Merino, Bradford J. Wood Int. J. CARS, DOI 10.1007/s11548-015-1287-x (2015)
Novel Human-like Influenza A Viruses Circulate in Swine in Mexico and Chile Martha Nelson, Marie R. Culhane, Albert Rovira, Montserrat Torremorell, Pedro Guerrero, and Julio Norambuena PLoS Currents, doi: 10.1371/currents.outbreaks.c8b3207c9bad98474eca3013fa933ca6 (2015)
Defining the Domain Arrangement of the Mammalian Target of Rapamycin Complex Component Rictor Protein Zhou P, Zhang N, Nussinov R, Ma B J. Comput. Biol., DOI://10.1089/cmb.2015.0103 (2015)
Three dysconnectivity patterns in treatment-resistant schizophrenia patients and their unaffected siblings Wang J, Cao H, Liao Y et al. Neuroimage Clin. , doi: 10.1016/j.nicl.2015.03.017 (2015)

The jigsaw puzzle of sequence phenotype inference: Piecing together Shannon entropy, importance sampling, and Empirical Bayes Shreif Z, Striegel DA, Periwal V J. Theoretical Biology, doi: 10.1016/j.jtbi.2015.06.010. (2015)
A Deep Insight Into the Sialotranscriptome of the Chagas Disease Vector, Panstrongylus megistus (Hemiptera: Heteroptera) Ribeiro JM, Schwarz A, Francischetti IM J. Med. Entomol., DOI://10.1093/jme/tjv023 (2015)
Deep Proteomic Profiling of Vasopressin-Sensitive Collecting Duct Cells. I. Virtual Western Blots and Molecular Weight Distributions Chin-Rang Yang, Pumipat Tongyoo, Milad Emamian, Pablo Concha Sandoval, Viswanathan Raghuram, Mark A. Knepper Am. J. Physiol. - Cell Physiol. , DOI: 10.1152/ajpcell.00213.2015 (2015)
Impact of conscious intent on chunking during motor learning Sunbin Song and Leonardo Cohen Learning & Memory, doi: 10.1101/lm.035824.114 (2015)
Small Retinoprotective Peptides Reveal a Receptor-binding Region on Pigment Epithelium-derived Factor Jason Kenealey, Preeti Subramanian, Antonella Comitato, Jeanee Bullock, Laura Keehan, Federica Polato, David Hoover, Valeria Marigo and S. Patricia Becerra J. Biol. Chem. , doi: 10.1074/jbc.M115.645846 (2015)
Amylin-Aβ oligomers at atomic resolution using molecular dynamics simulations: a link between Type 2 diabetes and Alzheimer's disease Michal Baram , Yoav Atsmon-Raz , Buyong Ma , Ruth Nussinov and Yifat Miller Phys. Chem. Chem. Phys., DOI: 10.1039/C5CP03338A (2015)

A Bayesian joint model of menstrual cycle length and fecundity Kirsten J. Lum, Rajeshwari Sundaram, Germaine M. Buck Louis andThomas A. Louis Biometrics, DOI: 10.1111/biom.12379 (2015)
Revealing the fate of cell surface human P-glycoprotein (ABCB1): The lysosomal degradation pathway Katayama, K; Kapoor, K; Ohnuma, S et al. Biochim. Biophys. Acta, DOI://10.1016/j.bbamcr.2015.06.001 (2015)
An Improved F(st) Estimator Chen, G; Yuan, A; Shriner, D et al. PLoS ONE, DOI://10.1371/journal.pone.0135368 (2015)
Genome-wide association study of neocortical Lewy-related pathology Terhi Peuralinna, Liisa Myllykangas, Minna Oinas,, Mike A. Nalls, Hannah A. D. Keage, Veli-Matti Isoviita, Miko Valori, Tuomo Polvikoski, Anders Paetau, Raimo Sulkava, Paul G. Ince, Julia Zaccai, Carol Brayne, Bryan J. Traynor, John Hardy, Andrew B. Singleton and Pentti J. Tienari Annalls of Clinical and Translational Neurology, DOI: 10.1002/acn3.231 (2015)
Confusing placebo effect with natural history in epilepsy: A big data approach Goldenholz DM, Moss R, Scott J, Auh S, Theodore WH Ann. Neurol., DOI://10.1002/ana.24470 (2015)
Possible Human Papillomavirus 38 Contamination of Endometrial Cancer RNA Sequencing Samples in The Cancer Genome Atlas Database Majid Kazemian, Min Ren, Jian-Xin Lin, Wei Liao, Rosanne Spolski and Warren J. Leonard J. Virology, doi: 10.1128/JVI.00822-15 (2015)

The Beta Cell in Its Cluster: Stochastic Graphs of Beta Cell Connectivity in the Islets of Langerhans Deborah A. Striegel, Manami Hara, Vipul Periwal PLoS Computational Biology, DOI: 10.1371/journal.pcbi.1004423 (2015)
Baseline genetic associations in the Parkinson's Progression Markers Initiative (PPMI) Mike A. Nalls, Margaux F. Keller, Dena G. Hernandez, Lan Chen, David J. Stone , Andrew B. Singleton, andon behalf of the Parkinson's Progression Marker Initiative (PPMI) investigators Movement Disorders, DOI: 10.1002/mds.26374 (2015)
Presenilin 1 Maintains Lysosomal Ca2+ Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification Ju-Hyun Lee, Mary Kate McBrayer, Devin M. Wolfe, Luke J. Haslett, Asok Kumar, Yutaka Sato, Pearl P.Y. Lie, Panaiyur Mohan, Erin E. Coffey, Uday Kompella, Claire H. Mitchell, Emyr Lloyd-Evans, Ralph A. Nixon Cell Reports , doi:10.1016/j.celrep.2015.07.050 (2015)
Modeling ligand recognition at the P2Y12 receptor in light of X-ray structural information Paoletta, S; Sabbadin, D; von Kügelgen, I et al. J. Comput. Aided Mol. Des., DOI://10.1007/s10822-015-9858-z (2015)
Gα13 Stimulates the Tyrosine Phosphorylation of Ric-8A Mingda Yan, Ji Ha, Danny Dhanasekaran J. Molecular Signaling, doi://10.5334/1750-2187-10-3 (2015)
Molecular structure of monomorphic peptide fibrils within a kinetically trapped hydrogel network Katelyn Nagy-Smith, Eric Moore, Joel Schneider, and Robert Tycko PNAS, doi: 10.1073/pnas.1509313112 (2015)

Divergence from the classical hydroboration reactivity; boron containing materials through a hydroboration cascade of small cyclic dienes Anna Andreou, Michal Leskes, Pablo G. Jambrina, Gary J. Tustin, Clare P. Grey, Edina Rosta, and Oren A. Scherman Chemical Science, DOI: 10.1039/b000000x (2015)
ABCC8 R1420H loss-of-function variant in a Southwest American Indian community: association with increased birth weight and doubled risk of type 2 diabetes Leslie J. Baier, Yunhua Li Muller, Maria Sara Remedi, Michael Traurig, Paolo Piaggi, Gregory Wiessner, Ke Huang, Alyssa Stacy, Sayuko Kobes, Jonathan Krakoff, Peter H. Bennett, Robert G. Nelson, William C. Knowler, Robert L. Hanson, Colin G. Nichols and Clifton Bogardus Diabetes, doi: 10.2337/db15-0459 (2015)
Comprehensive assembly of novel transcripts from unmapped human RNA-Seq data and their association with cancer Majid Kazemian, Min Ren, Jian‐Xin Lin, Wei Liao, Rosanne Spolski, Warren J Leonard Molecular Systems Biology, DOI 10.15252/msb.156172 (2015)
A β Stretching-and-Packing Cross-Seeding Mechanism Can Trigger Tau Protein Aggregation Ruxi Qi, Yin Luo, Guanghong Wei, Ruth Nussinov, and Buyong Ma J. Phys. Chem Letters, DOI: 10.1021/acs.jpclett.5b01447 (2015)
Membrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory Zoe Cournia, Toby W. Allen et al. J. Membrane Biology, DOI: 10.1007/s00232-015-9802-0 (2015)
Mechanical properties of lipid bilayers from molecular dynamics simulation Richard M. Venable, Frank L.H. Brown, Richard W. Pastor Chemistry and Physics of Lipids, doi:10.1016/j.chemphyslip.2015.07.014 (2015)

Runx1 is required for hematopoietic defects and leukemogenesis in Cbfb-MYH11 knock-in mice Hyde RK, Zhao L, Alemu L, Liu PP Leukemia, DOI://10.1038/leu.2015.58 (2015)
PTH and Vitamin D Repress DMP1 in Cementoblasts Wang L, Tran AB, Nociti FH Jr, Thumbigere-Math V, Foster BL, Krieger CC, Kantovitz KR, Novince CM, Koh AJ, McCauley LK, Somerman MJ J Dent Res. , doi: 10.1177/0022034515599726 (2015)
4'-modified nucleoside analogs: Potent inhibitors active against entecavir-resistant hepatitis B virus Takamatsu Y, Tanaka Y, Kohgo S,, Murakami S, Singh K, Das D, Venzon DJ, Amano M, Higashi-Kuwata N, Aoki M, Delino NS, Hayashi S, Takahashi S, Sukenaga Y, Haraguchi K, Sarafianos SG, Maeda K, Mitsuya H Hepatology, doi: 10.1002/hep.27962 (2015)
Super-enhancers: Asset management in immune cell genomes Steven Witte, John J. O'Shea, Golnaz Vahedi Trends in Immunology, doi: 10.1016/j.it.2015.07.005. (2015)
Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection Hadi M Yassine, Jeffrey C Boyington, Patrick M McTamney, Chih-Jen Wei, Masaru Kanekiyo, Wing-Pui Kong, John R Gallagher, Lingshu Wang, Yi Zhang, M Gordon Joyce, Daniel Lingwood, Syed M Moin, Hanne Andersen, Yoshinobu Okuno, Srinivas S Rao, Audray K Harris, Peter D Kwong, John R Mascola, Gary J Nabel & Barney S Graham Nature Medicine, doi:10.1038/nm.3927 (2015)
Mapsnp: an R package to plot a genomic map for single nucleotide polymorphisms Zhang F, Xu Y, Cao H, Jin C, Cheng Z, Wang G, Shugart YY PLoS One, doi: 10.1371/journal.pone.0123609 (2015)

Distinct transcriptome profiles differentiate nonsteroidal anti-inflammatory drug-dependent from nonsteroidal anti-inflammatory drug-independent food-induced anaphylaxis Muñoz-Cano R, Pascal M, Bartra J, Picado C, Valero A, Kim DK, Brooks S, Ombrello M, Metcalfe DD, Rivera J, Olivera A J Allergy Clin Immunol. , doi: 10.1016/j.jaci.2015.05.042. (2015)
Resting state connectivity of the bed nucleus of the stria terminalis at ultra-high field Salvatore Torrisi, Katherine O'Connell, Andrew Davis, Richard Reynolds, Nicholas Balderston, Julie Fudge, Christian Grillon and Monique Ernst Human Brain Mapping, DOI: 10.1002/hbm.22899 (2015)
Metabolic mapping of A3 adenosine receptor agonist MRS5980 Fang ZZ, Tosh DK, Tanaka N, Wang H, Krausz KW, O'Connor R, Jacobson KA, Gonzalez FJ Biochem Pharmacol., doi: 10.1016/j.bcp.2015.07.007. (2015)
RAG Represents a Widespread Threat to the Lymphocyte Genome Grace Teng, Yaakov Maman, Wolfgang Resch, Min Kim, Arito Yamane, Jason Qian, Kyong-Rim Kieffer-Kwon, Malay Mandal, Yanhong Ji, Eric Meffre, Marcus R. Clark, Lindsay G. Cowell, Rafael Casellas, David G. Schatz Cell, doi:10.1016/j.cell.2015.07.009 (2015)
Variation in the Williams syndrome GTF2I gene and anxiety proneness interactively affect prefrontal cortical response to aversive stimuli Jabbi M, Chen Q, Turner N, Kohn P, White M, Kippenhan JS, Dickinson D, Kolachana B, Mattay V, Weinberger DR, Berman KF Transl Psychiatry., doi: 10.1038/tp.2015.98. (2015)
Improved Expression and Characterization of a Multidomain Xylanase from Thermoanaerobacterium aotearoense SCUT27 in Bacillus subtilis Xiongliang Huang, Zhe Li, Chenyu Du, Jufang Wang, and Shuang Li J. Agric. Food Chem., DOI: 10.1021/acs.jafc.5b01259 (2015)

Areas of Brain Damage Underlying Increased Reports of Behavioral Disinhibition Knutson, KM; Dal Monte, O; Schintu, S et al. J Neuropsychiatry Clin Neurosci, DOI://10.1176/appi.neuropsych.14060126 (2015)
Opposing roles of STAT1 and STAT3 in IL-21 function in CD4+ T cells Wan, CK; Andraski, AB; Spolski, R et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1511711112 (2015)
Gene-Gene Interaction Among WNT Genes for Oral Cleft in Trios Li Q, Kim Y, Suktitipat B, Hetmanski JB, Marazita ML, Duggal P, Beaty TH, Bailey-Wilson JE Genet Epidemiol., doi: 10.1002/gepi.21888. (2015)
Convergent BOLD and Beta-Band Activity in Superior Temporal Sulcus and Frontolimbic Circuitry Underpins Human Emotion Cognition Jabbi M, Kohn PD, Nash T, Ianni A, Coutlee C, Holroyd T, Carver FW, Chen Q, Cropp B, Kippenhan JS, Robinson SE, Coppola R, Berman KF Cerebral Cortex, doi: 10.1093/cercor/bht427. (2015)
An Integrative Genomic Study Implicates the Post-Synaptic Density in the Pathogenesis of Bipolar Disorder Akula N, Wendland JR, Choi KH, McMahon FJ Neuropsychopharmacology, doi: 10.1038/npp.2015.218 (2015)
A mutation of MET, encoding hepatocyte growth factor receptor, is associated with human DFNB97 hearing loss Mujtaba G, Schultz JM, Imtiaz A, Morell RJ, Friedman TB, Naz S J. Med. Genet., DOI://10.1136/jmedgenet-2015-103023 (2015)

Directional dominance on stature and cognition in diverse human populations Joshi, PK; Esko, T; Mattsson, H et al. Nature, DOI://10.1038/nature14618 (2015)
A two-state mixed hidden Markov model for risky teenage driving behavior John C. Jackson, Paul S. Albert, and Zhiwei Zhang Ann. Appl. Stat., doi:10.1214/14-AOAS765 (2015)
Women Workers and Women at Home Are Equally Inactive: NHANES 2003-2006 Steeves JA, Murphy RA, Zipunnikov V, Strath SJ, Harris TB Med Sci Sports Exerc, DOI://10.1249/MSS.0000000000000582 (2015)
Novel genomic signals of recent selection in an Ethiopian population Tekola-Ayele, F; Adeyemo, A; Chen, G et al. Eur. J. Hum. Genet., DOI://10.1038/ejhg.2014.233 (2015)
Genome Analysis of Latin American Cervical Cancer: Frequent Activation of the PIK3CA Pathway Hong Lou, Guillermo Villagran, Joseph F. Boland, Kate M Im, Sarita Polo, Weiyin Zhou, Ushie Odey, Eligia Juàrez-Torres, Ingrid Medina-Martìnez, Edgar Roman-Basaure, Jason Mitchell, David Roberson, Julie Sawitzke, Lisa Garland, Maria Rodrìguez-Herrera, David Wells, Jennifer Troyer, Francisco Castillo, Sara Bass, Xijun Zhang, Miriam Castillo, Bert Gold, Hesler Morales, Meredith Yeager, Jaime Berumen, Enrique Alvirez, Eduardo Gharzouzi, and Michael Dean Clinical Cancer Research, doi:10.1158/1078-0432.CCR-14-1837 (2015)
Classification of occupational activity categories using accelerometry: NHANES 2003-2004 Steeves JA, Tudor-Locke C, Murphy RA, King GA, Fitzhugh EC, Harris TB Int J Behav Nutr Phys Act, DOI://10.1186/s12966-015-0235-z (2015)

Bolaamphiphiles as Carriers for siRNA Delivery: From Chemical Syntheses to Practical Applications Kshitij Gupta, Kirill A. Afonin, Mathias Viarda, Virginia Herrero, Wojciech Kasprzak, Ioannis Kagiampakis, Taejin Kim, Alexey Y. Koyfman, Anu Puri, Marissa Stepler, Alison Sappe, Vineet N. KewalRamani, Sarina Grinberg, Charles Linder, Eliahu Heldman, Robert Blumenthal, Bruce A. Shapiro J. Controlled Release, doi:10.1016/j.jconrel.2015.06.041 (2015)
MitoRCA-seq reveals unbalanced cytocine to thymine transition in Polg mutant mice Ni T, Wei G, Shen T, Han M, Lian Y, Fu H, Luo Y, Yang Y, Liu J, Wakabayashi Y, Li Z, Finkel T, Xu H, Zhu J Scientific Reports, doi: 10.1038/srep12049. (2015)
Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci Demerath, EW; Guan, W; Grove, ML et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddv161 (2015)
A Systems Level Analysis of Vasopressin-mediated Signaling Networks in Kidney Distal Convoluted Tubule Cells Lei Cheng, Qi Wu, Marleen L. A. Kortenoeven, Trairak Pisitkun, Robert A. Fenton Sci. Rep. , doi: 10.1038/srep12829 (2015)
Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations Sonia Shah, Marc J. Bonder, Riccardo E. Marioni et al. Am. J. Hum. Genet. , doi:/10.1016/j.ajhg.2015.05.014 (2015)
2.2 Å resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor Alberto Bartesaghi, Alan Merk, Soojay Banerjee, Doreen Matthies, Xiongwu Wu, Jacqueline L. S. Milne, Sriram Subramaniam Science, DOI: 10.1126/science.aab1576 (2015)

miR-23a impairs bone differentiation in osteosarcoma via down-regulation of GJA1 Gindin Y, Jiang Y, Francis P, Walker RL, Abaan OD, Zhu YJ, Meltzer PS Front Genet. , doi: 10.3389/fgene.2015.00233 (2015)
Motif signatures in stretch enhancers are enriched for disease-associated genetic variants Daniel X Quang, Michael R Erdos, Stephen C J Parker,and Francis S Collins Epigenetics Chromatin, doi: 10.1186/s13072-015-0015-7. (2015)
Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools Ding J, Sidore C, Butler TJ, Wing MK, Qian Y, Meirelles O, Busonero F, Tsoi LC, Maschio A, Angius A, Kang HM, Nagaraja R, Cucca F, Abecasis GR, Schlessinger D PLoS Genetics, doi: 10.1371/journal.pgen.1005306 (2015)
EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion Yang XP, Jiang K, Hirahara K, Vahedi G, Afzali B, Sciume G, Bonelli M, Sun HW, Jankovic D, Kanno Y, Sartorelli V, O'Shea JJ, Laurence A Scientific Reports, doi: 10.1038/srep10643 (2015)
Recurrent Mutations in the Basic Domain of TWIST2 Cause Ablepharon Macrostomia and Barber-Say Syndromes Marchegiani, S; Davis, T; Tessadori, F et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2015.05.017 (2015)
An Insight into the Sialome of the Lone Star Tick, Amblyomma americanum, with a Glimpse on Its Time Dependent Gene Expression Karim S, Ribeiro JM PLoS ONE, DOI://10.1371/journal.pone.0131292 (2015)

Positing, fitting, and selecting regression models for pooled biomarker data Mitchell EM, Lyles RH, Schisterman EF Stat Med, DOI://10.1002/sim.6496 (2015)
Metabolic Regulation of Histone Acetyltransferases by Endogenous Acyl-CoA Cofactors Montgomery DC, Sorum AW, Guasch L, Nicklaus MC, Meier JL Chem Biol., doi: 10.1016/j.chembiol.2015.06.015. (2015)
Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder , ; de Moor, MH; van den Berg, SM et al. JAMA Psychiatry, DOI://10.1001/jamapsychiatry.2015.0554 (2015)
RNA-Seq analysis of high NaCl-induced gene expression Izumi Y, Yang W, Zhu J, Burg MB, Ferraris JD Physiol Genomics., doi: 10.1152/physiolgenomics.00057.2015 (2015)
Transcriptome dynamics of developing photoreceptors in three-dimensional retina cultures recapitulates temporal sequence of human cone and rod differentiation revealing cell surface markers and gene networks Kaewkhaw R, Kaya KD, Brooks M, Homma K, Zou J, Chaitankar V, Rao M, Swaroop A Stem Cells, doi: 10.1002/stem.2122. (2015)
Dietary fatty acids modulate associations between genetic variants and circulating fatty acids in plasma and erythrocyte membranes: Meta-analysis of nine studies in the CHARGE consortium Smith, CE; Follis, JL; Nettleton, JA et al. Mol Nutr Food Res, DOI://10.1002/mnfr.201400734 (2015)

GTP-Dependent K-Ras Dimerization Muratcioglu S, Chavan TS, Freed BC, Jang H, Khavrutskii L, Freed RN, Dyba MA, Stefanisko K, Tarasov SG, Gursoy A, Keskin O, Tarasova NI, Gaponenko V, Nussinov R Structure, doi: 10.1016/j.str.2015.04.019 (2015)
New monogenic autoinflammatory diseases--a clinical overview Canna SW, Goldbach-Mansky R Semin Immunopathol. , oi: 10.1007/s00281-015-0493-5 (2015)
Tracking ongoing cognition in individuals using brief, whole-brain functional connectivity patterns Javier Gonzalez-Castillo, Colin W. Hoy, Daniel A. Handwerker, Meghan E. Robinson, Laura C. Buchanan, Ziad S. Saad, and Peter A. Bandettini PNAS, doi: 10.1073/pnas.1501242112 (2015)
Forgetting the best when predicting the worst: Preliminary observations on neural circuit function in adolescent social anxiety Jarcho JM, Romer AL, Shechner T, Galvan A, Guyer AE, Leibenluft E, Pine DS, Nelson EE Dev Cogn Neurosci. , doi: 10.1016/j.dcn.2015.03.002 (2015)
Influenza A Viruses of Human Origin in Swine, Brazil Martha I. Nelson , Rejane Schaefer, Danielle Gava, Maurìcio Egĩdio Cantão, and Janice Reis Ciacci-Zanella Emerg Infect Dis. , doi://10.3201/eid2108.141891 (2015)
Acute and recent air pollution exposure and cardiovascular events at labour and delivery Tuija Männistö, Pauline Mendola, Katherine Laughon Grantz, Kira Leishear, Rajeshwari Sundaram, Seth Sherman, Qi Ying, Danping Liu Heart, doi:10.1136/heartjnl-2014-307366 (2015)

Proteomic analysis of the kidney filtration barrier�Problems and perspectives Markus M. Rinschen Thomas Benzing, Kavee Limbutara and Trairak Pisitkun Proteomics Clinical Applications, DOI: 10.1002/prca.201400201 (2015)
Homologous Mutation to Human BRAF V600E Is Common in Naturally Occurring Canine Bladder Cancer--Evidence for a Relevant Model System and Urine-Based Diagnostic Test Decker B, Parker HG, Dhawan D, Kwon EM, Karlins E, Davis BW, Ramos-Vara JA, Bonney PL, McNiel EA, Knapp DW, Ostrander EA Mol Cancer Res, doi: 10.1158/1541-7786.MCR-14-0689 (2015)
Nucleosome adaptability conferred by sequence and structural variations in histone H2A-H2B dimers Shaytan AK, Landsman D, Panchenko AR Curr Opin Struct Biol., doi: 10.1016/j.sbi.2015.02.004 (2015)
Possible HPV38 contamination of endometrial cancer RNA-Seq samples in The Cancer Genome Atlas database Majid Kazemian, Min Ren, Jian-Xin Lin, Wei Liao, Rosanne Spolski and Warren J. Leonard J. Virology, doi: 10.1128/JVI.00822-15 (2015)
Coupling of Zinc-Binding and Secondary Structure in Nonfibrillar Aβ40 Peptide Oligomerization Xu L, Shan S, Chen Y, Wang X, Nussinov R, Ma B J Chem Inf Model, DOI://10.1021/acs.jcim.5b00063 (2015)
Assessment of Cancer Cell Line Representativeness Using Microarrays for Merkel Cell Carcinoma Kenneth Daily, Amy Coxon, Jonathan S Williams, Chyi-Chia R Lee, Daniel G Coit, Klaus J Busam and Isaac Brownell J. Investigative Dermatology, doi:10.1038/jid.2014.518 (2015)

Shared genetic basis for migraine and ischemic stroke Rainer Malik, Tobias Freilinger et al. Neurology, doi: 10.1212/WNL.0000000000001606 (2015)
Quantitative Interpretation of FRET Experiments via Molecular Simulation: Force Field and Validation Robert B. Best, Hagen Hofmann, Daniel Nettell, Benjamin Schuler Biochemistry, doi:10.1016/j.bpj.2015.04.038 (2015)
DNA methylome and transcriptome sequencing in human ovarian granulosa cells links age-related changes in gene expression to gene body methylation and 3'-end GC density Yu B, Russanova VR, Gravina S, Hartley S, Mullikin JC, Ignezweski A6 Graham J, Segars JH, DeCherney AH, Howard BH Oncotarget, 6(6): 3627-3643. (2015)
Gene Level Meta-Analysis of Quantitative Traits by Functional Linear Models Ruzong Fan, Yifan Wang, Michael Boehnke, Wei Chen, Yun Li, Haobo Ren, Iryna Lobach and Momiao Xiong Genetics, doi: 10.1534/genetics.115.178343 (2015)
Homology modeling of larger proteins guided by chemical shifts Yang Shen & Ad Bax Nature Methods, doi:10.1038/nmeth.3437 (2015)
Conformational processing of oncogenic v-Src kinase by the molecular chaperone Hsp90 Edgar E. Boczek , Lasse G. Reefschläger, Marco Dehling, Tobias J. Struller , Elisabeth Häusler , Andreas Seidl , Ville R. I. Kaila , and Johannes Buchner PNAS, oi: 10.1073/pnas.1424342112 (2015)

Insertion Sequence IS26 Reorganizes Plasmids in Clinically Isolated Multidrug-Resistant Bacteria by Replicative Transposition He, S; Hickman, AB; Varani, AM et al. MBio, DOI://10.1128/mBio.00762-15 (2015)
Etiologic Ischemic Stroke Phenotypes in the NINDS Stroke Genetics Network Hakan Ay, Ethem Murat Arsava, Gunnar Andsberg et al. Stroke, doi: 10.1161/STROKEAHA.114.007362 (2015)
Identification of microRNAs specific for epithelial cell adhesion molecule�positive tumor cells in hepatocellular carcinoma Junfang Ji, Xin Zheng, Marshonna Forgues, Taro Yamashita, Eliane L. Wauthier, Lola M. Reid, Xinyu Wen, Young Song, Jun S. Wei, Javed Khan, Snorri S. Thorgeirsson andXin Wei Wang Hepatology, doi: 10.1002/hep.27886. (2015)
High-level expression of human arginase I in Pichia pastoris and its immobilization on chitosan to produce L-ornithine Xue Zhang, Jin Liu, Xianhong Yu, Fei Wang, Li Yi, Zhezhe Li, Yunyun Liu, and Lixin Macorresponding author BMC Biotechnol. , doi: 10.1186/s12896-015-0184-2 (2015)
Expression and Characterization of the RKOD DNA Polymerase in Pichia pastoris Fei Wang, Shuntang Li, Hui Zhao, Lu Bian, Liang Chen, Zhen Zhang, Xing Zhong, Lixin Ma, Xiaolan Yu PLoS One, doi: 10.1371/journal.pone.0131757 (2015)
Model-free functional connectivity and impulsivity correlates of alcohol dependence: a resting-state study Zhu X, Cortes CR, Mathur K, Tomasi D, Momenan R Addict Biol. , doi: 10.1111/adb.12272 (2015)

Pretreatment Differences in BOLD Response to Emotional Faces Correlate with Antidepressant Response to Scopolamine Furey ML, Drevets WC, Szczepanik J, Khanna A, Nugent A, Zarate CA Int. J. Neuropsychopharmacol., DOI://10.1093/ijnp/pyv028 (2015)
Sliding Motility, Biofilm Formation, and Glycopeptidolipid Production in Mycobacterium colombiense Strains Maya-Hoyos M, Leguizam�n J, Mari�o-Ram�rez L, Soto CY Biomed Res Int. , doi: 10.1155/2015/419549 (2015)
Gene expression markers of age-related inflammation in two human cohorts Pilling LC, Joehanes R, Melzer D, Harries LW, Henley W, Dupuis J, Lin H, Mitchell M, Hernandez D, Ying SX, Lunetta KL, Benjamin EJ, Singleton A, Levy D, Munson P, Murabito JM, Ferrucci L Exp Gerontol. , doi: 10.1016/j.exger.2015.05.012 (2015)
The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence P Suchankova, J Yan, M L Schwandt, B L Stangl, E C Caparelli, R Momenan, E Jerlhag, J A Engel, C A Hodgkinson, M Egli, M F Lopez, H C Becker, D Goldman, M Heilig, V A Ramchandani, and L Leggio Transl Psychiatry. , doi: 10.1038/tp.2015.68 (2015)
Topological polymorphism of the two-start chromatin fiber Norouzi D, Zhurkin VB Biophys. J., doi: 10.1016/j.bpj.2015.04.015 (2015)
A genome-wide association study of suicidal behavior Galfalvy H, Haghighi F, Hodgkinson C, Goldman D, Oquendo MA, Burke A, Huang YY, Giegling I, Rujescu D, Bureau A, Turecki G, Mann JJ Am J Med Genet B Neuropsychiatr Genet. , doi: 10.1002/ajmg.b.32330 (2015)

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors Zhou T, Lynch RM, Chen L et al. Cell, doi: 10.1016/j.cell.2015.05.007 (2015)
Group Differences in MEG-ICA Derived Resting State Networks: Application to Major Depressive Disorder Allison C. Nugent, Stephen E. Robinson, Richard Coppola, Maura L. Furey, Carlos A. Zarate Jr NeuroImage, doi:10.1016/j.neuroimage.2015.05.051 (2015)
APOL1 G1 genotype modifies the association between HDLC and kidney function in African Americans Bentley, AR; Divers, J; Shriner, D et al. BMC Genomics, DOI://10.1186/s12864-015-1645-7 (2015)
A liver-enriched long non-coding RNA, lncLSTR, regulates systemic lipid metabolism in mice Li P, Ruan X, Yang L, Kiesewetter K, Zhao Y, Luo H, Chen Y, Gucek M, Zhu J, Cao H Cell Metabolism, doi: 10.1016/j.cmet.2015.02.004 (2015)
24, 25-Dihydroxyvitamin D 3 and Vitamin D Status of Community-Dwelling Black and White Americans Anders H. Berg, Camille E. Powe, Michele K. Evans, Julia Wenger, Guillermo Ortiz, Alan B. Zonderman, Pirianthini Suntharalingam, Kathryn Lucchesi, Neil R. Powe, S. Ananth Karumanchi, and Ravi I. Thadhani Clinical Chemistry, doi:10.1373/clinchem.2015.240051 (2015)
A cis-eQTL in PFKFB2 is associated with diabetic nephropathy, adiposity and insulin secretion in American Indians Muller YL, Piaggi P, Hanson RL, Kobes S, Bhutta S, Abdussamad M, Leak-Johnson T, Kretzler M, Huang , Weil EJ, Nelson RG, Knowler WC, Bogardus C, Baier LJ Hum Mol Genet. , doi: 10.1093/hmg/ddv040 (2015)

Endoplasmic reticulum-associated amino-peptidase 1 and rheumatic disease: genetics Ombrello MJ, Kastner DL, Remmers EF Curr Opin Rheumatol, DOI://10.1097/BOR.0000000000000189 (2015)
Converging evidence implicates the abnormal microRNA system in schizophrenia. Zhang F, Xu Y, Shugart YY, Yue W, Qi G, Yuan G, Cheng Z, Yao J, Wang J, Wang G, Cao H, Guo W, Zhou Z, Wang Z, Tian L, Jin C, Yuan J, Liu C, Zhang D Schizophrenia Bulletin, doi: 10.1093/schbul/sbu (2015)
Confirmation of genetic variants associated with lethal prostate cancer in a cohort of men from hereditary prostate cancer families Karyadi DM, Zhao S, He Q, McIntosh L, Wright JL, Ostrander EA, Feng Z, Stanford JL. Int. J. Cancer, doi: 10.1002/ijc.29241 (2015)
Baseline working memory activation deficits in dimensional anxious depression as detected by magnetoencephalography Ionescu, DF; Nugent, AC; Luckenbaugh, DA et al. Acta Neuropsychiatr, DOI://10.1017/neu.2014.46 (2015)
Mutation-targeted therapy with sunitinib or everolimus in patients with advanced low-grade or intermediate-grade neuroendocrine tumours of the gastrointestinal tract and pancreas with or without cytoreductive surgery: protocol for a phase II clinical trial Neychev, V; Steinberg, SM; Cottle-Delisle, C et al. BMJ Open, DOI://10.1136/bmjopen-2015-008248 (2015)
Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project Paul L. Auer, Mike Nalls, James F. Meschia, et al. JAMA Neurology, doi:10.1001/jamaneurol.2015.0582 (2015)

Aβ(1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease Yiling Xiao, Buyong Ma, Dan McElheny, Sudhakar Parthasarathy, Fei Long, Minako Hoshi, Ruth Nussinov & Yoshitaka Ishii Nat Struct Mol Biol, doi:10.1038/nsmb.2991 (2015)
Infrared, Raman, and Ultraviolet Absorption Spectra and Theoretical Calculations and Structure of 2,3,5,6-Tetrafluoropyridine in its Ground and Excited Electronic States Hong-Li Sheu, Praveenkumar Boopalachandran, Sunghwan Kim, Jaan Laane Chemical Physics, doi:10.1016/j.chemphys.2015.04.011 (2015)
PAPST, a User Friendly and Powerful Java Platform for ChIP-Seq Peak Co-Localization Analysis and Beyond Paul W. Bible , Yuka Kanno, Lai Wei, Stephen R. Brooks, John J. O'Shea, Maria I. Morasso, Rasiah Loganantharaj, Hong-Wei Sun PLoS One, DOI: 10.1371/journal.pone.0127285 (2015)
Deep Sequencing Analysis of the Ixodes ricinus Haemocytome Kotsyfakis M, Kopáček P, Franta Z, Pedra JH, Ribeiro JM PLoS Negl Trop Dis, DOI://10.1371/journal.pntd.0003754 (2015)
Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus Tinoush Moulaei, Kabamba B Alexandre, Shilpa R Shenoy, Joel R Meyerson, Lauren RH Krumpe, Brian Constantine, Jennifer Wilson, Robert W Buckheit, Jr., James B McMahon, Sriram Subramaniam, Alexander Wlodawer, Barry R O'Keefe Retrovirology, doi: 10.1186/s12977-014-0127-3 (2015)
High-level expression and characterization of a thermophilic β-mannanase from Aspergillus niger in Pichia pastoris Shi Yu, Zhezhe Li, Yaping Wang, Wanping Chen, Lin Fu, Wei Tang, Chen Chen, Yunyun Liu, Xue Zhang, Lixin Ma Biotechnology Letters, doi://10.1007/s10529-015-1848-7 (2015)
Vasopressin-regulated miRNAs and AQP2-targeting miRNAs in kidney collecting duct cells Jae-Eun Kim, Hyun Jun Jung, Yu-Jung Lee, Tae-Hwan Kwon Am. J. Physiol. - Renal Physiol., DOI: 10.1152/ajprenal.00334.2014 (2015)
Cooperativity and evolution of Tetrahymena two-domain arginine kinase Noriko Okazaki, Shou Motomura, Nanaka Okazoe, Daichi Yano, Tomohiko Suzuki Int. J. Biological Macromolecules, doi:10.1016/j.ijbiomac.2015.05.034 (2015)
New findings support the association of DISC1 genetic variants with susceptibility to schizophrenia in the Han Chinese population Luo X, Jin C, Zhou Z, Shugart YY, Liu X, Zhang F, Zhang F, Zhu J, Wang Y, Cheng Z Psychiatry Res., doi: 10.1016/j.psychres.2015.05.115 (2015)
Combined influence of linker DNA and histone tails on nucleosome dynamics as revealed by microsecond molecular dynamics simulations Alexey K. Shaytana, Grigoriy A. Armeev, Alexander Goncearenco, Victor B. Zhurkin, David Landsman & Anna R. Panchenkoa J Biomol Struct Dyn., doi: 10.1080/07391102.2015.1032630. (2015)
Transcriptional activation by the thyroid hormone receptor through ligand-dependent receptor recruitment and chromatin remodelling Lars Grøntved, Joshua J. Waterfall, Dong Wook Kim, Songjoon Baek, Myong-Hee Sung, Li Zhao, Jeong Won Park, Ronni Nielsen, Robert L. Walker, Yuelin J. Zhu, Paul S. Meltzer, Gordon L. Hager & Sheue-yann Cheng Nature Communications, doi:10.1038/ncomms8048 (2015)
Elucidation of RNA binding regions of gonadotropin-regulated testicular RNA helicase (GRTH/DDX25) to transcripts of a chromatin remodeling protein essential for spermatogenesis Ruifeng Yang, Chon-Hwa Tsai-Morris, Jung Hoon Kang, Maria L. Dufau Hormone Molecular Biology and Clinical Investigation, DOI: 10.1515/hmbci-2015-0004 (2015)

A combined coarse-grained and all-atom simulation of TRPV1 channel gating and heat activation Wenjun Zheng and Feng Qin J. Gen. Physiol. , doi: 10.1085/jgp.201411335 (2015)
Mixed model and estimating equation approaches for zero inflation in clustered binary response data with application to a dating violence study Kara A. Fulton, Danping Liu, Denise L. Haynie, and Paul S. Albert The Annals of Applied Statistics, doi:10.1214/14-AOAS791 (2015)
Cortisol Stress Response in Men and Women Modulated Differentially by the Mu-Opioid Receptor Gene Polymorphism OPRM1 A118G Lovallo WR, Enoch MA, Acheson A, Cohoon AJ, Sorocco KH, Hodgkinson CA, Vincent AS, Glahn DC, Goldman D Neuropsychopharmacology., doi: 10.1038/npp.2015.101 (2015)
The DNA repair endonuclease Mus81 facilitates fast DNA replication in the absence of exogenous damage Fu H, Martin MM, Regairaz M, Huang L, You Y, Lin CM, Ryan M, Kim R, Shimura T, Pommier Y, Aladjem M Nature Communications, doi: 10.1038/ncomms7746. (2015)
miR-26a and miR-384-5p are required for LTP maintenance and spine enlargement Gu QH, Yu D, Hu Z, Liu X, Yang Y, Luo Y, Zhu J, Li Z Nature Communications, doi: 10.1038/ncomms7789 (2015)
High incidence of unrecognized visceral/neurological late-onset Niemann-Pick disease, type C1, predicted by analysis of massively parallel sequencing data sets Wassif CA, Cross JL, Iben J, Sanchez-Pulido L, Cougnoux A, Platt FM, Ory DS, Ponting CP, Bailey-Wilson JE, Biesecker LG, Porter FD Genet Med. , doi: 10.1038/gim.2015.25. (2015)

Molecular profiling and targeted therapy for advanced thoracic malignancies: a biomarker-derived, multiarm, multihistology phase II basket trial Lopez-Chavez A, Thomas A, Rajan A, Raffeld M, Morrow B, Kelly R, Carter CA, Guha U, Killian K, Lau CC, Abdullaev Z, Xi L, Pack S, Meltzer PS, Corless CL, Sandler A, Beadling C, Warrick A, Liewehr DJ, Steinberg SM, Berman A, Doyle A, Szabo E, Wang Y, Giaccone G J Clin Oncol. , doi: 10.1200/JCO.2014.58.2007 (2015)
p53 loss increases the osteogenic differentiation of bone marrow stromal cells He Y, de Castro LF, Shin MH, Dubois W, Yang HH, Jiang S, Mishra PJ, Ren L, Gou H, Lal A, Khanna C, Merlino G, Lee M, Robey PG, Huang J. Stem Cells, doi: 10.1002/stem.1925. (2015)
Commensal-dendritic-cell interaction specifies a unique protective skin immune signature Naik S, Bouladoux N, Linehan JL, Han SJ, Harrison OJ, Wilhelm C, Conlan S, Himmelfarb S, Byrd AL, Deming C, Quinones M, Brenchley JM, Kong HH, Tussiwand R, Murphy KM, Merad M, Segre JA, Belkaid Y Nature, doi: 10.1038/nature14052 (2015)
Automated prostate cancer detection using T2-weighted and high-b-value diffusion-weighted magnetic resonance imaging Jin Tae Kwak, Sheng Xu, Bradford J. Wood, Baris Turkbey, Peter L. Choyke, Peter A. Pinto, Shijun Wang and Ronald M. Summers Medical Physics, doi://10.1118/1.4918318 (2015)
SNPfisher: tools for probing genetic variation in laboratory-reared zebrafish Matthew G. Butler, James R. Iben, Kurt C. Marsden, Jonathan A. Epstein, Michael Granato and Brant M. Weinstein Development, doi: 10.1242/dev.118786 (2015)
X Chromosome and Autosome Dosage Responses in Drosophila melanogaster Heads Zhen-Xia Chen and Brian Oliver Genes | Genomes | Genetics, doi://10.1534/g3.115.017632 (2015)

Dissecting the Roles of MicroRNAs in Coronary Heart Disease via Integrative Genomic Analyses Tianxiao Huan, Jian Rong, Kahraman Tanriverdi, Qingying Meng, Anindya Bhattacharya, David D. McManus, Roby Joehanes, Themistocles L. Assimes, Ruth McPherson, Nilesh J. Samani, Jeanette Erdmann, Heribert Schunkert, Coronary ARteryDIsease Genome wide Replication and Meta-analysis (CARDIoGRAM) Consortium, Paul Courchesne, Peter J. Munson, Andrew D. Johnson, Christopher J. O'Donnell, Bin Zhang, Martin G. Larson, Jane E. Freedman, Daniel Levy, Xia Yang Arteriosclerosis, Thrombosis, and Vascular Biology, doi: 10.1161/ATVBAHA.114.305176 (2015)
Mutations decouple proton transfer from phosphate cleavage in the dUTPase catalytic reaction Anna Lopata, Pablo G. Jambrina, Pankaz K. Sharma, Bernard R. Brooks, Judit Toth, Beata G. Vertessy, and Edina Rosta ACS Catalysis, DOI: 10.1021/cs502087f (2015)
Pleiotropy Analysis of Quantitative Traits at Gene Level by Multivariate Functional Linear Models Wang Y, Liu A, Mills JL, Boehnke M, Wilson AF, Bailey-Wilson JE, Xiong M, Wu CO, Fan R Genet Epidemiol., doi: 10.1002/gepi.21895 (2015)
Modeling the effect of codon translation rates on co-translational protein folding mechanisms of arbitrary complexity Luca Caniparoli and Edward P. O'Brien J. Chem. Phys., doi://10.1063/1.4916914 (2015)
A Functional Data Analysis Approach for Circadian Patterns of Activity of Teenage Girls Ruzong Fan, Victoria Chen, Yunlong Xie, Lanlan Yin, Sungduk Kim, Paul S Albert, Bruce Simons-Morton J. Circadian Rhythms, DOI: 10.5334/jcr.ac (2015)
Continual Reintroduction of Human Pandemic H1N1 Influenza A Viruses into Swine in the United States, 2009 to 2014 Martha I. Nelson, Jered Stratton, Mary Lea Killian, Alicia Janas-Martindale and Amy L. Vincent J. Virology, doi: 10.1128/JVI.00459-15 (2015)

Global migration of influenza A viruses in swine Martha I. Nelson, Cècile Viboud, Amy L. Vincent, Marie R. Culhane, Susan E. Detmer, David E. Wentworth, Andrew Rambaut, Marc A. Suchard, Edward C. Holmes & Philippe Lemey Nature Communications, doi:10.1038/ncomms7696 (2015)
Towards predicting metastatic progression of melanoma based on gene expression data Yuanyuan Li, Juno M. Krahn, Gordon P. Flake, David M. Umbach andLeping Li Pigment Cell and Melanoma Research, DOI: 10.1111/pcmr.12374 (2015)
An Integrated Bayesian Nonparametric Approach for Stochastic and Variability Orders in ROC Curve Estimation: An Application to Endometriosis Diagnosis Beom Seuk Hwang & Zhen Chena* J. Am. Stat. Assoc., DOI:10.1080/01621459.2015.1023806 (2015)
Identification of Mutational Hot Spots for Substrate Diffusion: Application to Myoglobin David De Sancho, Adam Kubas, Po-Hung Wang, Jochen Blumberger, and Robert B. Best J. Chem. Theory Comput. , DOI: 10.1021/ct5011455 (2015)
Genome-wide identification of microRNA expression quantitative trait loci Tianxiao Huan, Jian Rong, Chunyu Liu, Xiaoling Zhang, Kahraman Tanriverdi, Roby Joehanes, Brian H. Chen, Joanne M. Murabito, Chen Yao, Paul Courchesne, Peter J. Munson, Christopher J. O'Donnell, Nancy Cox, Andrew D. Johnson, Martin G. Larson, Daniel Levy & Jane E. Freedman Nature Communications, doi:10.1038/ncomms7601 (2015)
Molecular modeling of the human P2Y14 receptor: A template for structure-based design of selective agonist ligands Kevin Trujillo, Silvia Paoletta, Evgeny Kiselev, Kenneth A. Jacobson Bioorganic & Medicinal Chemistry, doi:10.1016/j.bmc.2015.03.042 (2015)

Detection and characterization of nonspecific, sparsely populated binding modes in the early stages of complexation Antonio Cardone, Aaron Bornstein, Harish C. Pant, Mary Brady, Ram Sriram and Sergio A. Hassan J. Computational Chemistry, DOI: 10.1002/jcc.23883 (2015)
Single-unit activity during natural vision: diversity, consistency, and spatial sensitivity among AF face patch neurons McMahon DB, Russ BE, Elnaiem HD, Kurnikova AI, Leopold DA J. Neurosci., DOI://10.1523/JNEUROSCI.3825-14.2015 (2015)
An Apela RNA-Containing Negative Feedback Loop Regulates p53-Mediated Apoptosis in Embryonic Stem Cells Li M, Gou H, Tripathi BK, Huang J, Jiang S, Dubois W, Waybright T, Lei M, Shi J, Zhou M, Huang J Cell Stem Cell , doi: 10.1016/j.stem.2015.04.002 (2015)
Expression, Activation and Characterization of Porcine Trypsin in Pichia pastoris GS115 Min Shu, Wei Shen, Xiaojuan Wang, Fei Wang, Lixin Ma, , Chao Zhai Protein Expression and Purification, Protein Expression and Purification (2015)
The Structure of an Oxalate Oxidoreductase Provides Insight into Microbial 2-Oxoacid Metabolism Marcus I. Gibson, Edward J. Brignole, Elizabeth Pierce, Mehmet Can Stephen W. Ragsdale, and Catherine L. Drennan Biochemistry, DOI: 10.1021/acs.biochem.5b00521 (2015)
Mutation rate and genotype variation of Ebola virus from Mali case sequences T. Hoenen, D. Safronetz, A. Groseth, K. R. Wollenberg, O. A. Koita, B. Diarra, I. S. Fall, F. C. Haidara, F. Diallo, M. Sanogo, Y. S. Sarro, A. Kone, A. C. G. Togo, A. Traore, M. Kodio, A. Dosseh, K. Rosenke, E. de Wit, F. Feldmann, H. Ebihara, V. J. Munster, K. C. Zoon, H. Feldmann, S. Sow Science, DOI: 10.1126/science.aaa5646 (2015)

Deep Sequencing in Microdissected Renal Tubules Identifies Nephron Segment-Specific Transcriptomes Jae Wook Lee, Chung-Lin Chou and Mark A. Knepper J. Am. Soc. Nephrology, doi: 10.1681/ASN.2014111067 (2015)
S Values for 131I based on the ICRP Adult Voxel Phantoms Stephanie Lamart, Steven L. Simon, Andre Bouville, Brian E. Moroz and Choonsik Lee Radiation Protection Dosimetry, doi: 10.1093/rpd/ncv016 (2015)
Engineering of customized meganucleases via in vitro compartmentalization and in cellulo optimization Ryo Takeuchi, Michael Choi, Barry L. Stoddard Methods Mol Biol., doi: 10.1007/978-1-4939-1862-1_6 (2015)
The relationship between glucose metabolism, resting-state fMRI BOLD signal, and GABAA-binding potential: a preliminary study in healthy subjects and those with temporal lobe epilepsy Nugent AC, Martinez A, D'Alfonso A, Zarate CA, Theodore WH J. Cereb. Blood Flow Metab., DOI://10.1038/jcbfm.2014.228 (2015)
Is visual registration equivalent to semiautomated registration in prostate biopsy Kwak, JT; Hong, CW; Pinto, PA et al. Biomed Res Int, DOI://10.1155/2015/394742 (2015)
Rare variants in neuronal excitability genes influence risk for bipolar disorder Ament SA, Szelinger S, Glusman G, Ashworth J, Hou L, Akula N, Shekhtman T, Badner JA, Brunkow ME, Mauldin DE, Stittrich AB, Rouleau K, Detera-Wadleigh SD, Nurnberger JI Jr, Edenberg HJ, Gershon ES, Schork N; Bipolar Genome Study, Price ND, Gelinas R, Hood L, Craig D, McMahon FJ, Kelsoe JR, Roach JC PNAS, doi: 10.1073/pnas.1424958112 (2015)

Computational and experimental studies of reassociating RNA/DNA hybrids containing split functionalities Afonin KA, Bindewald E, Kireeva M, Shapiro BA Methods Enzymol. , doi: 10.1016/bs.mie.2014.10.058 (2015)
Common genetic variants influence human subcortical brain structures Hibar DP, Stein JL, Renteria ME et al. Nature, doi: 10.1038/nature14101 (2015)
Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium Li Q, Wojciechowski R, Simpson CL et al. Human Genetics, doi: 10.1007/s00439-014-1500-y. (2015)
The bigger they are, the harder they fall: A topical review on sedimented solutes for solid-state NMR Enrico Ravera Concepts in Magnetic Resonance, DOI: 10.1002/cmr.a.21318 (2015)
Renal Type A Intercalated Cells Contain Albumin in Organelles with Aldosterone-Regulated Abundance Thomas Buus Jensen, Muhammad Umar Cheema, Agata Szymiczek, Helle Hasager Damkier, and Jeppe Praetorius PLoS One, doi: 10.1371/journal.pone.0124902 (2015)
A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension Tianxiao Huan , Tõnu Esko , Marjolein J. Peters et al. PLoS Genetics, DOI: 10.1371/journal.pgen.1005035 (2015)
Nucleus detection using gradient orientation information and linear least squares regression Jin Tae Kwak ; Stephen M. Hewitt ; Sheng Xu ; Peter A. Pinto ; Bradford J. Wood Proc. SPIE Medical Imaging 2015, doi:10.1117/12.2081413 (2015)
Characterization of the p300 Taz2-p53 TAD2 complex and comparison with the p300 Taz2-p53 TAD1 complex Miller Jenkins, LM; Feng, H; Durell, SR et al. Biochemistry, DOI://10.1021/acs.biochem.5b00044 (2015)
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility Jennifer Wessel, Audrey Y Chu, Sara M Willems et al. Nature Communications, doi: 10.1038/ncomms6897 (2015)
A Rapid and Simple Screening Method to Identify Conditions for Enhanced Stability of Modular Vaccine Candidates Alemu Tekewe, Natalie K. Connorsa , Frank Sainsbury, Nani Wibowo, Linda H.L. Lua, Anton P.J. Middelberg Biochemical Engg. Journal, doi:10.1016/j.bej.2015.04.004 (2015)
Computational Structural Analysis of C-Terminal Residues of Proteins Containing Transmembrane Regions M.C. Rishyakulya, K.M. Saravanan Int. J. Comp. Biol. 4(1):44-54 (2015)
Clonality and Evolutionary History of Rhabdomyosarcoma Li Chen , Jack F. Shern , Jun S. Wei, Marielle E. Yohe, Young K. Song, Laura Hurd, Hongling Liao, Daniel Catchpoole, Stephen X. Skapek, Frederic G. Barr, Douglas S. Hawkins, Javed Khan PLos Genetics, DOI: 10.1371/journal.pgen.1005075 (2015)

Practice Structure Improves Unconscious Transitional Memories by Increasing Synchrony in a Premotor Network. Song S, Gotts SJ, Dayan E, Cohen LG. J. Cognitive Neuroscience, doi:10.1162/jocna00796 (2015)
Tissue- and time-dependent transcription in Ixodes ricinus salivary glands and midguts when blood feeding on the vertebrate host Kotsyfakis M, Schwarz A, Erhart J, Ribeiro JM Sci Rep, DOI://10.1038/srep09103 (2015)
Permutation Testing for Treatment-Covariate Interactions and Subgroup Identification Jared C. Foster, Bin Nan, Lei Shen, Niko Kaciroti, Jeremy M. G. Taylor Statistics in Bioscience, DOI 10.1007/s12561-015-9125-9 (2015)
Burden of Serious Infections in Adults With Systemic Lupus Erythematosus: A National Population-Based Study, 1996-2011 Maria G. Tektonidou, Zhong Wang, Abhijit Dasgupta and Michael M. Ward Arthritis Care and Research, DOI: 10.1002/acr.22575 (2015)
Synthesis and cell-selective antitumor properties of amino acid conjugated tumor-associated carbohydrate antigen-coated gold nanoparticles Biswas S, Medina SH, Barchi JJ Carbohydr. Res., DOI://10.1016/j.carres.2014.11.002 (2015)
Chromatin Architecture Reorganization during Stem Cell Differentiation Dixon JR, Jung I, Selvaraj S, Shen Y, Antosiewicz-Bourget JE, Lee AY, Ye Z, Kim A, Rajagopal N, Xie W, Diao Y, Liang J, Zhao H, Lobanenkov VV, Ecker JR, Thomson JA, Ren B Nature, doi: 10.1038/nature14222 (2015)

Dependence of Internal Friction on Folding Mechanism Wenwei Zheng, David De Sancho, Travis Hoppe, and Robert B. Best JACS, DOI: 10.1021/ja511609u (2015)
Mechanisms of Membrane Binding of Small GTPase K-Ras4B Farnesylated Hypervariable Region Hyunbum Jang, Sherwin J. Abraham, Tanmay S. Chavan, Ben Hitchinson, Lyuba Khavrutskii, Nadya I. Tarasova, Ruth Nussinov and Vadim Gaponenko J. Biol. Chem. , doi: 10.1074/jbc.M114.620724 (2015)
Predicting the Impact of Missense Mutations on Protein-Protein Binding Affinity Minghui Li, Marharyta Petukh, Emil Alexov, and Anna R. Panchenko J Chem Theory Comput., doi: 10.1021/ct401022c (2015)
Quantitative residue-specific protein backbone torsion angle dynamics from concerted measurement of 3J couplings Lee JH, Li F, Grishaev A, Bax A. J Am Chem Soc. , doi: 10.1021/ja512593s (2015)
Genome accessibility is widely preserved and locally modulated during mitosis Hsiung CC, Morrissey CS, Udugama M, Frank CL, Keller CA, Baek S, Giardine B, Crawford GE, Sung MH, Hardison RC, Blobel GA Genome Res. , doi: 10.1101/gr.180646 (2015)
Structure and dynamics of the fibronectin-III domains of Aplysia californica cell adhesion molecules Catherine M. Kelly , Julien Muzard , Bernard R. Brooks , Gil Lee and Nicolae-Viorel Buchete Phys. Chem. Chem. Phys., DOI: 10.1039/C4CP05307A (2015)

A Novel Tricyclic Ligand-Containing Nonpeptidic HIV-1 Protease Inhibitor, GRL-0739, Effectively Inhibits the Replication of Multidrug-Resistant HIV-1 Variants and Has a Desirable Central Nervous System Penetration Property In Vitro Masayuki Amano, Yasushi Tojo, Pedro Miguel Salcedo-Gòmez, Garth L. Parham, Prasanth R. Nyalapatla, Debananda Das, Arun K. Ghosh and Hiroaki Mitsuya Antimicrob Agents Chemother., doi: 10.1128/AAC.04757-14 (2015)
Identification of common genetic variants controlling transcript isoform variation in human whole blood Xiaoling Zhang, Roby Joehanes, Brian H Chen, Tianxiao Huan, Saixia Ying, Peter J Munson, Andrew D Johnson, Daniel Levy & Christopher J O'Donnell Nature Genetics, doi:10.1038/ng.3220 (2015)
Whole-genome sequencing to understand the genetic architecture of common gene expression and biomarker phenotypes Andrew R. Wood, Marcus A. Tuke, Mike Nalls et al. Hum Mol Genet., doi: 10.1093/hmg/ddu560 (2015)
Visualizing transient dark states by NMR spectroscopy Anthis NJ, Clore GM Q. Rev. Biophys., DOI://10.1017/S0033583514000122 (2015)
Analysis of the contribution of experimental bias, experimental noise, and inter-subject biological variability on the assessment of developmental trajectories in diffusion MRI studies of the brain Sadeghi, N; Nayak, A; Walker, L et al. Neuroimage, DOI://10.1016/j.neuroimage.2014.12.084 (2015)
Functional MRI mapping of dynamic visual features during natural viewing in the macaque Russ BE, Leopold DA Neuroimage, DOI://10.1016/j.neuroimage.2015.01.012 (2015)

Systems biology of polycystic kidney disease: a critical review Menezes LF, Germino GG Wiley Interdiscip Rev Syst Biol Med, DOI://10.1002/wsbm.1289 (2015)
High-Level Expression of Endo-β-N-Acetylglucosaminidase H from Streptomyces plicatus in Pichia pastoris and Its Application for the Deglycosylation of Glycoproteins Fei Wang, Xiaojuan Wang, Xiaolan Yu, Lin Fu, Yunyun Liu, Lixin Ma , Chao Zhai PLoS One, DOI: 10.1371/journal.pone.0120458 (2015)
A Genome-wide Association Study of Myasthenia Gravis Alan E. Renton, Hannah A. Pliner, Carlo Provenzano et al. JAMA Neurology, doi:10.1001/jamaneurol.2014.4103 (2015)
An Equilibrium Model for the Combined Effect of Macromolecular Crowding and Surface Adsorption on the Formation of Linear Protein Fibrils Travis Hoppe1, Allen P. Minton Biophys. J. , doi:10.1016/j.bpj.2014.12.033 (2015)
DNA methylation age of blood predicts all-cause mortality in later life Marioni, RE, Shah, S, McRae, AF, Chen, BH, Colicino, E, Harris, SE, Gibson, J, Henders, AK, Redmond, P, Cox, SR, Pattie, A, Corley, J, Murphy, L, Martin, NG, Montgomery, GW, Feinberg, AP, Fallin, M, Multhaup, ML, Jaffe, AE, Joehanes, R, Schwartz, J, Just, AC, Lunetta, KL, Murabito, JM, Starr, JM, Horvath, S, Baccarelli, AA, Levy, D, Visscher, PM, Wray, NR & Deary, IJ Genome Biology, doi://10.1186/s13059-015-0584-6 (2015)
Addressing population-specific multiple testing burdens in genetic association studies Sobota, RS; Shriner, D; Kodaman, N et al. Ann. Hum. Genet., DOI://10.1111/ahg.12095 (2015)

Stretch-Enhancers Delineate Disease-Associated Regulatory Nodes in T Cells Golnaz Vahedi, Yuka Kanno, Yasuko Furumoto, Kan Jiang, Stephen C. J. Parker, Michael R. Erdos, Sean R. Davis, Rahul Roychoudhuri, Nicholas P. Restifo, Massimo Gadina, Zhonghui Tang, Yijun Ruan, Francis S. Collins, Vittorio Sartorelli & John J. O'Shea Nature, doi:10.1038/nature14154 (2015)
Allosteric Effects of the Oncogenic RasQ61L Mutant on Raf-RBD. Fetics SK, Guterres H, Kearney BM, Buhrman G, Ma B, Nussinov R, Mattos C Structure, doi: 10.1016/j.str.2014.12.017 (2015)
Dynamics of chromatin accessibility and long-range interactions in response to glucocorticoid pulsing Stavreva DA, Coulon A, Baek S, Sung MH, John S, Stixova L, Tesikova M, Hakim O, Miranda T, Hawkins M, Stamatoyannopoulos JA, Chow CC, Hager GL Genome Res. , doi: 10.1101/gr.184168.114 (2015)
Role of contingency in striatal response to incentive in adolescents with anxiety Benson BE, Guyer AE, Nelson EE, Pine DS, Ernst M Cogn Affect Behav Neurosci, DOI://10.3758/s13415-014-0307-6 (2015)
The NAD(+)-dependent SIRT1 deacetylase translates a metabolic switch into regulatory epigenetics in skeletal muscle stem cells Ryall, JG; Dell'Orso, S; Derfoul, A et al. Cell Stem Cell, DOI://10.1016/j.stem.2014.12.004 (2015)
Efficient Data Mining for Local Binary Pattern in Texture Image Analysis Jin Tae Kwak, , Sheng Xu , Bradford J. Wood Expert Systems with Applications, doi:10.1016/j.eswa.2015.01.055 (2015)
What's Next for Next-Gen Sequencing? MaryAnn Labant Genetic Engineering and Biotechnology News, doi:10.1089/gen.35.03.02. (2015)
Vasopressin-responsive miRNAs and AQP2-targeting miRNAs in kidney collecting duct cells Jae-Eun Kim , Hyun Jun Jung , Yu-Jung Lee , Tae-Hwan Kwon Am. J. Physiol. - Renal Physiol., DOI: 10.1152/ajprenal.00334.2014 (2015)
A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins Guntur Fibriansah, Joanne L. Tan et al. Nature Communications, doi:10.1038/ncomms7341 (2015)
Design, Synthesis, and Application of Spinach Molecular Beacons Triggered by Strand Displacement Sanchita Bhadra, Andrew D. Ellington Methods in Enzymology, doi:10.1016/bs.mie.2014.10.049 (2015)
Transcriptional profiles reveal a stepwise developmental program of memory CD8(+) T cell differentiation Roychoudhuri, R; Lefebvre, F; Honda, M et al. Vaccine, DOI://10.1016/j.vaccine.2014.10.007 (2015)
Myosin II controls cellular branching morphogenesis and migration in three dimensions by minimizing cell-surface curvature Elliott, H; Fischer, RS; Myers, KA et al. Nat. Cell Biol., DOI://10.1038/ncb3092 (2015)

Optimizing the order of hypotheses in serial testing of multiple endpoints in clinical trials. Zhang Z, Wang C, Troendle JF. Stat. Med., doi: 10.1002/sim.6425. (2015)
CENP-A nucleosomes localize to transcription factor hotspots and subtelomeric sites in human cancer cells Rajbir K Athwal, Marcin P Walkiewicz, Songjoon Baek, Song Fu, Minh Bui, Jordi Camps, Thomas Ried, Myong-Hee Sung and Yamini Dalal Epigenetics and Chromatin, doi:10.1186/1756-8935-8-2 (2015)
Coupled-Cluster Studies of Extensive Green Fluorescent Protein Models Using the Reduced Virtual Space Approach Robert Send , Carl-Mikael Suomivuori , Ville R. I. Kaila , and Dage Sundholm J. Phys. Chem. B, DOI: 10.1021/jp5120898 (2015)
Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma Shakhova, O; Cheng, P; Mishra, PJ et al. PLoS Genet., DOI://10.1371/journal.pgen.1004877 (2015)
Withdrawal from long-term methamphetamine self-administration 'normalizes' neurometabolites in rhesus monkeys: a (1) H MR spectroscopy study Yang S, Belcher AM, Chefer S, Vaupel DB, Schindler CW, Stein EA, Yang Y. Addict Biol., doi: 10.1111/adb.12078. (2015)
Molecular basis of the polyspecificity of P-glycoprotein (ABCB1): recent biochemical and structural studies Chufan EE, Sim HM, Ambudkar SV Adv Cancer Res, doi: 10.1016/bs.acr.2014.10.003 (2015)

fMRI functional connectivity applied to adolescent neurodevelopment Ernst M, Torrisi S, Balderston N, Grillon C, Hale EA. Annu Rev Clin Psychol., doi: 10.1146/annurev-clinpsy-032814-112753 (2015)
A systematic heritability analysis of the human whole blood transcriptome. Huan T, Liu C, Joehanes R, Zhang X, Chen BH, Johnson AD, Yao C, Courchesne P, O'Donnell CJ, Munson PJ, Levy D. Human Genetics (2015)
Detecting Functional Connectivity during Audiovisual Integration with MEG: a Comparison of Connectivity Metrics. Ard TD, Carver F, Holroyd T, Horwitz B, Coppola R. Brain Connect. (2015)
Cerebro-cerebellar connectivity is increased in primary lateral sclerosis Meoded A, Morrissette AE, Katipally R, Schanz O, Gotts SJ, Floeter MK Neuroimage Clin, DOI://10.1016/j.nicl.2014.12.009 (2015)
Functional mapping of face-selective regions in the extrastriate visual cortex of the marmoset Hung, CC; Yen, CC; Ciuchta, JL et al. J. Neurosci., DOI://10.1523/JNEUROSCI.2659-14.2015 (2015)
Modulation of Alzheimer's Aβ protofilament-membrane interactions by lipid headgroups. Tofoleanu F, Brooks BR, Buchete NV. ACS Chem Neurosci., doi://abs/10.1021/cn500277f (2015)

Insights into the Mechanism of Inhibition of CXCR4: Identification of Piperidinylethanamine Analogs as Anti-HIV-1 Inhibitors Das D, Maeda K, Hayashi Y, Gavande N, Desai DV, Chang SB, Ghosh AK, Mitsuya H Antimicrob Agents Chemother., pii: AAC.04654-14. (2015)
Variable selection method for the identification of epistatic models Holzinger ER, Szymczak S, Dasgupta A, Malley J, Li Q, Bailey-Wilson JE Pac Symp Biocomput, 2335-6936 (2015)
CDD: NCBI's conserved domain database Marchler-Bauer, A; Derbyshire, MK; Gonzales, NR et al. Nucleic Acids Res., DOI://10.1093/nar/gku1221 (2015)
Analysis of soluble protein entry into primary cilia using semipermeabilized cells David K. Breslow, Maxence V. Nachury Methods in Cell Biology, doi:10.1016/bs.mcb.2014.12.006 (2015)
NRG1, ERBB4 and AKT1 Epistasis Increases Schizophrenia Risk and is Biologically Validated via Functional Neuroimaging in Healthy Controls Nicodemus KK, Law AJ, Radulescu E, Luna A, Kolachana B, Vakkalanka R, Rujescu D, Giegling I, Straub RE, McGee K, Gold B, Dean M, Muglia P, Callicott JH, Tan HY, Weinberger DR. Arch Gen Psychiatry, doi: 10.1001/archgenpsychiatry.2010.117 (2015)
Maturation of the HIV-1 core by a non-diffusional phase transition Frank GA, Narayan K, Bess JW Jr, Del Prete GQ, Wu X, Moran A, Hartnell LM, Earl LA, Lifson JD, Subramaniam S Nature Communications, doi: 10.1038/ncomms6854 (2015)

Meta-analysis of Correlated Traits via Summary Statistics from GWASs with an Application in Hypertension Xiaofeng Zhu, Tao Feng, Bamidele O. Tayo et al. Am J Hum Genet., doi: 10.1016/j.ajhg.2014.11.011. (2015)
Protein structural information derived from NMR chemical shift with the neural network program TALOS-N Shen Y, Bax A Methods Mol. Biol., DOI://10.1007/978-1-4939-2239-0_2 (2015)
BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones Kanno T, Kanno Y, LeRoy G, Campos E, Sun HW, Brooks SR, Vahedi G, Heightman TD, Garcia BA, Reinberg D, Siebenlist U, O'Shea JJ, Ozato K Nat Struct Mol Biol., doi: 10.1038/nsmb.2912 (2015)
Structures of oxalate oxidoreductase : C₂ activation by a microbial TPP-dependent ferredoxin oxidoreductase Gibson, Marcus Ian PhD Thesis, MIT Dept of Chemistry (2015)

2014 (267 papers)

Teneurin-4 promotes cellular protrusion formation and neurite outgrowth through focal adhesion kinase signaling Suzuki, N; Numakawa, T; Chou, J et al. FASEB J., DOI://10.1096/fj.13-241034 (2014)
Targeted H3R26 deimination specifically facilitates estrogen receptor binding by modifying nucleosome structure Guertin, MJ; Zhang, X; Anguish, L et al. PLoS Genet., DOI://10.1371/journal.pgen.1004613 (2014)
Loss of signalling via Gα13 in germinal centre B-cell-derived lymphoma Muppidi, JR; Schmitz, R; Green, JA et al. Nature, DOI://10.1038/nature13765 (2014)
NEP: web server for epitope prediction based on antibody neutralization of viral strains with diverse sequences Chuang, GY; Liou, D; Kwong, PD; Georgiev, IS; Nucleic Acids Res., DOI://10.1093/nar/gku318 (2014)
Structural basis of resistance to anti-cytochrome bc₁ complex inhibitors: implication for drug improvement Esser, L; Yu, CA; Xia, D; Curr. Pharm. Des., DOI://10.2174/138161282005140214163327 (2014)
Concurrent alterations in TERT, KDM6A, and the BRCA pathway in bladder cancer Nickerson, ML; Dancik, GM; Im, KM et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-14-0330 (2014)
Ciliopathy-associated gene Cc2d2a promotes assembly of subdistal appendages on the mother centriole during cilia biogenesis Veleri, S; Manjunath, SH; Fariss, RN et al. Nat Commun, DOI://10.1038/ncomms5207 (2014)
A new approach to radial basis function approximation and its application to QSAR Zakharov, AV; Peach, ML; Sitzmann, M; Nicklaus, MC; J Chem Inf Model, DOI://10.1021/ci400704f (2014)

Applications of multivariate modeling to neuroimaging group analysis: a comprehensive alternative to univariate general linear model Chen, G; Adleman, NE; Saad, ZS; Leibenluft, E; Cox, RW; Neuroimage, DOI://10.1016/j.neuroimage.2014.06.027 (2014)
An electrocorticographic electrode array for simultaneous recording from medial, lateral, and intrasulcal surface of the cortex in macaque monkeys Fukushima, M; Saunders, RC; Mullarkey, M; Doyle, AM; Mishkin, M; Fujii, N; J. Neurosci. Methods, DOI://10.1016/j.jneumeth.2014.06.022 (2014)
Towards a mechanistic understanding of pathological anxiety: the dorsal medial prefrontal-amygdala 'aversive amplification' circuit in unmedicated generalized and social anxiety disorders Robinson, OJ; Krimsky, M; Lieberman, L; Allen, P; Vytal, K; Grillon, C; Lancet Psychiatry, DOI://10.1016/S2215-0366(14)70305-0 (2014)
Genome Sequences of Vibrio navarrensis, a Potential Human Pathogen Gladney, LM; Katz, LS; Knipe, KM et al. Genome Announc, DOI://10.1128/genomeA.01188-14 (2014)
Perlecan is required for FGF-2 signaling in the neural stem cell niche Kerever, A; Mercier, F; Nonaka, R et al. Stem Cell Res, DOI://10.1016/j.scr.2013.12.009 (2014)
Molecular architecture of transcription factor hotspots in early adipogenesis Siersbæk, R; Baek, S; Rabiee, A et al. Cell Rep, DOI://10.1016/j.celrep.2014.04.043 (2014)

A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors Petrini, I; Meltzer, PS; Kim, IK et al. Nat. Genet., DOI://10.1038/ng.3016 (2014)
Clonal tracking of rhesus macaque hematopoiesis highlights a distinct lineage origin for natural killer cells Wu, C; Li, B; Lu, R et al. Cell Stem Cell, DOI://10.1016/j.stem.2014.01.020 (2014)
Overlapping chromatin-remodeling systems collaborate genome wide at dynamic chromatin transitions Morris, SA; Baek, S; Sung, MH et al. Nat. Struct. Mol. Biol., DOI://10.1038/nsmb.2718 (2014)
Single-molecule sequencing to track plasmid diversity of hospital-associated carbapenemase-producing Enterobacteriaceae Conlan, S; Thomas, PJ; Deming, C et al. Sci Transl Med, DOI://10.1126/scitranslmed.3009845 (2014)
Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function Tang, W; Kowgier, M; Loth, DW et al. PLoS ONE, DOI://10.1371/journal.pone.0100776 (2014)
Role of myelin plasticity in oscillations and synchrony of neuronal activity Pajevic, S; Basser, PJ; Fields, RD; Neuroscience, DOI://10.1016/j.neuroscience.2013.11.007 (2014)

High-resolution traction force microscopy Plotnikov, SV; Sabass, B; Schwarz, US; Waterman, CM; Methods Cell Biol., DOI://10.1016/B978-0-12-420138-5.00020-3 (2014)
Elucidation of the structural basis of interaction of the BCR-ABL kinase inhibitor, nilotinib (Tasigna) with the human ABC drug transporter P-glycoprotein Shukla, S; Chufan, EE; Singh, S et al. Leukemia, DOI://10.1038/leu.2014.21 (2014)
miR-155 activates cytokine gene expression in Th17 cells by regulating the DNA-binding protein Jarid2 to relieve polycomb-mediated repression Escobar, TM; Kanellopoulou, C; Kugler, DG et al. Immunity, DOI://10.1016/j.immuni.2014.03.014 (2014)
Transcriptional and epigenetic networks of helper T and innate lymphoid cells Shih, HY; Sciumè, G; Poholek, AC et al. Immunol. Rev., DOI://10.1111/imr.12208 (2014)
High rate of disease-related copy number variations in childhood onset schizophrenia Ahn, K; Gotay, N; Andersen, TM et al. Mol. Psychiatry, DOI://10.1038/mp.2013.59 (2014)
Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci Simpson, CL; Wojciechowski, R; Oexle, K et al. PLoS ONE, DOI://10.1371/journal.pone.0107110 (2014)
A C-terminal fragment of fibulin-7 interacts with endothelial cells and inhibits their tube formation in culture de Vega, S; Suzuki, N; Nonaka, R et al. Arch. Biochem. Biophys., DOI://10.1016/j.abb.2014.01.013 (2014)
High prevalence of MAP2K1 mutations in variant and IGHV4-34-expressing hairy-cell leukemias Waterfall, JJ; Arons, E; Walker, RL et al. Nat. Genet., DOI://10.1038/ng.2828 (2014)
Structure and immune recognition of trimeric pre-fusion HIV-1 Env Pancera, M; Zhou, T; Druz, A et al. Nature, DOI://10.1038/nature13808 (2014)
Synthesis, biological, and biophysical studies of DAG-indololactones designed as selective activators of RasGRP Garcia, LC; Donadío, LG; Mann, E et al. Bioorg. Med. Chem., DOI://10.1016/j.bmc.2014.04.024 (2014)
Neonatal health of infants born to mothers with asthma Mendola, P; Männistö, TI; Leishear, K; Reddy, UM; Chen, Z; Laughon, SK; J. Allergy Clin. Immunol., DOI://10.1016/j.jaci.2013.06.012 (2014)
Conformational distribution and α-helix to β-sheet transition of human amylin fragment dimer Qi, R; Luo, Y; Ma, B; Nussinov, R; Wei, G; Biomacromolecules, DOI://10.1021/bm401406e (2014)

Dipeptide analysis of p53 mutations and evolution of p53 family proteins Huang, Q; Yu, L; Levine, AJ; Nussinov, R; Ma, B; Biochim. Biophys. Acta, DOI://10.1016/j.bbapap.2013.04.002 (2014)
Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma Hysi, PG; Cheng, CY; Springelkamp, H et al. Nat. Genet., DOI://10.1038/ng.3087 (2014)
Prediction of nucleosome rotational positioning in yeast and human genomes based on sequence-dependent DNA anisotropy Cui, F; Chen, L; LoVerso, PR; Zhurkin, VB; BMC Bioinformatics, DOI://10.1186/1471-2105-15-313 (2014)
Design and synthesis of human ABCB1 (P-glycoprotein) inhibitors by peptide coupling of diverse chemical scaffolds on carboxyl and amino termini of (S)-valine-derived thiazole amino acid Singh, S; Prasad, NR; Chufan, EE et al. J. Med. Chem., DOI://10.1021/jm401966m (2014)
Building through breaking: the development of cancer neochromosomes Waterfall, JJ; Meltzer, PS; Cancer Cell, DOI://10.1016/j.ccell.2014.10.013 (2014)
Mutant ADA2 in vasculopathies Kastner, DL; Zhou, Q; Aksentijevich, I; N. Engl. J. Med., DOI://10.1056/NEJMc1405506 (2014)
Transient estrogen receptor binding and p300 redistribution support a squelching mechanism for estradiol-repressed genes Guertin, MJ; Zhang, X; Coonrod, SA; Hager, GL; Mol. Endocrinol., DOI://10.1210/me.2014-1130 (2014)
RSC-dependent constructive and destructive interference between opposing arrays of phased nucleosomes in yeast Ganguli, D; Chereji, RV; Iben, JR; Cole, HA; Clark, DJ; Genome Res., DOI://10.1101/gr.177014.114 (2014)
Tyrosine sulfation in the second variable loop (V2) of HIV-1 gp120 stabilizes V2-V3 interaction and modulates neutralization sensitivity Cimbro, R; Gallant, TR; Dolan, MA et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1314718111 (2014)
Rotational positioning of nucleosomes facilitates selective binding of p53 to response elements associated with cell cycle arrest Cui, F; Zhurkin, VB; Nucleic Acids Res., DOI://10.1093/nar/gkt943 (2014)
Mutations of epigenetic regulatory genes are common in thymic carcinomas Wang, Y; Thomas, A; Lau, C et al. Sci Rep, DOI://10.1038/srep07336 (2014)
A closed-loop model of the respiratory system: focus on hypercapnia and active expiration Molkov, YI; Shevtsova, NA; Park, C et al. PLoS ONE, DOI://10.1371/journal.pone.0109894 (2014)
Laminin α1 regulates age-related mesangial cell proliferation and mesangial matrix accumulation through the TGF-β pathway Ning, L; Kurihara, H; de Vega, S et al. Am. J. Pathol., DOI://10.1016/j.ajpath.2014.02.006 (2014)
Family-based tests applied to extended pedigrees identify rare variants related to hypertension Xu, M; Wang, HZ; Guo, W; Qin, H; Shugart, YY; BMC Proc, DOI://10.1186/1753-6561-8-S1-S31 (2014)
Genome sequencing highlights the dynamic early history of dogs Freedman, AH; Gronau, I; Schweizer, RM et al. PLoS Genet., DOI://10.1371/journal.pgen.1004016 (2014)
Independence of familial transmission of mania and depression: results of the NIMH family study of affective spectrum disorders Merikangas, KR; Cui, L; Heaton, L et al. Mol. Psychiatry, DOI://10.1038/mp.2013.116 (2014)
pY RNA1-s2: a highly retina-enriched small RNA that selectively binds to Matrin 3 (Matr3) Yamazaki, F; Kim, HH; Lau, P et al. PLoS ONE, DOI://10.1371/journal.pone.0088217 (2014)
Sex- and age-interacting eQTLs in human complex diseases Yao, C; Joehanes, R; Johnson, AD et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddt582 (2014)

Experimental basis for a new allosteric model for multisubunit proteins Viappiani, C; Abbruzzetti, S; Ronda, L et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1413566111 (2014)
Comparison of gene expression microarray data with count-based RNA measurements informs microarray interpretation Richard, AC; Lyons, PA; Peters, JE et al. BMC Genomics, DOI://10.1186/1471-2164-15-649 (2014)
KDM5B focuses H3K4 methylation near promoters and enhancers during embryonic stem cell self-renewal and differentiation Kidder, BL; Hu, G; Zhao, K; Genome Biol., DOI://10.1186/gb-2014-15-2-r32 (2014)
Genomics of CpG methylation in developing and developed zebrafish McGaughey, DM; Abaan, HO; Miller, RM; Kropp, PA; Brody, LC; G3 (Bethesda), DOI://10.1534/g3.113.009514 (2014)
Control of cell identity genes occurs in insulated neighborhoods in mammalian chromosomes Dowen, JM; Fan, ZP; Hnisz, D et al. Cell, DOI://10.1016/j.cell.2014.09.030 (2014)
The power comparison of the haplotype-based collapsing tests and the variant-based collapsing tests for detecting rare variants in pedigrees Guo, W; Shugart, YY; BMC Genomics, DOI://10.1186/1471-2164-15-632 (2014)

Gain-of-function CCR4 mutations in adult T cell leukemia/lymphoma Nakagawa, M; Schmitz, R; Xiao, W et al. J. Exp. Med., DOI://10.1084/jem.20140987 (2014)
A mouse model of HIES reveals pro- and anti-inflammatory functions of STAT3 Steward-Tharp, SM; Laurence, A; Kanno, Y et al. Blood, DOI://10.1182/blood-2013-09-523167 (2014)
Genetic associations with expression for genes implicated in GWAS studies for atherosclerotic cardiovascular disease and blood phenotypes Zhang, X; Johnson, AD; Hendricks, AE et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddt461 (2014)
Sparse representation based biomarker selection for schizophrenia with integrated analysis of fMRI and SNPs Cao, H; Duan, J; Lin, D; Shugart, YY; Calhoun, V; Wang, YP; Neuroimage, DOI://10.1016/j.neuroimage.2014.01.021 (2014)
Transcriptional profiling of Wnt3a mutants identifies Sp transcription factors as essential effectors of the Wnt/β-catenin pathway in neuromesodermal stem cells Dunty, WC; Kennedy, MW; Chalamalasetty, RB; Campbell, K; Yamaguchi, TP; PLoS ONE, DOI://10.1371/journal.pone.0087018 (2014)
Interleukin-1 and interferon-γ orchestrate β-glucan-activated human dendritic cell programming via IκB-ζ modulation Cardone, M; Dzutsev, AK; Li, H et al. PLoS ONE, DOI://10.1371/journal.pone.0114516 (2014)

Dimerization of HIV-1 protease occurs through two steps relating to the mechanism of protease dimerization inhibition by darunavir Hayashi, H; Takamune, N; Nirasawa, T et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1400027111 (2014)
Whole blood gene expression and interleukin-6 levels Lin, H; Joehanes, R; Pilling, LC et al. Genomics, DOI://10.1016/j.ygeno.2014.10.003 (2014)
Single mutations in tau modulate the populations of fibril conformers through seed selection Meyer, V; Dinkel, PD; Luo, Y et al. Angew. Chem. Int. Ed. Engl., DOI://10.1002/anie.201308473 (2014)
Complete Genome Sequence of a Klebsiella pneumoniae Isolate with Chromosomally Encoded Carbapenem Resistance and Colibactin Synthesis Loci Conlan, S; Deming, C; Tsai, YC et al. Genome Announc, DOI://10.1128/genomeA.01332-14 (2014)
Mutations in TBC1D24, a gene associated with epilepsy, also cause nonsyndromic deafness DFNB86 Rehman, AU; Santos-Cortez, RL; Morell, RJ et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2013.12.004 (2014)
Synthesis of a des-B-ring bryostatin analogue leads to an unexpected ring expansion of the bryolactone core Kraft, MB; Poudel, YB; Kedei, N et al. J. Am. Chem. Soc., DOI://10.1021/ja5078188 (2014)
QSAR modeling of imbalanced high-throughput screening data in PubChem Zakharov, AV; Peach, ML; Sitzmann, M; Nicklaus, MC; J Chem Inf Model, DOI://10.1021/ci400737s (2014)
Modulation of miR-29 expression by α-fetoprotein is linked to the hepatocellular carcinoma epigenome Parpart, S; Roessler, S; Dong, F et al. Hepatology, DOI://10.1002/hep.27200 (2014)
Diacylglycerol lactones targeting the structural features that distinguish the atypical C1 domains of protein kinase C ζ and ι from typical C1 domains Pu, Y; Kang, JH; Sigano, DM et al. J. Med. Chem., DOI://10.1021/jm500165n (2014)
Pharmacophore modeling of nilotinib as an inhibitor of ATP-binding cassette drug transporters and BCR-ABL kinase using a three-dimensional quantitative structure-activity relationship approach Shukla, S; Kouanda, A; Silverton, L; Talele, TT; Ambudkar, SV; Mol. Pharm., DOI://10.1021/mp400762h (2014)
Synthesis of seco-B-ring bryostatin analogue WN-1 via C-C bond-forming hydrogenation: critical contribution of the B-ring in determining bryostatin-like and phorbol 12-myristate 13-acetate-like properties Andrews, IP; Ketcham, JM; Blumberg, PM et al. J. Am. Chem. Soc., DOI://10.1021/ja507825s (2014)
Enumeration of ring-chain tautomers based on SMIRKS rules Guasch, L; Sitzmann, M; Nicklaus, MC; J Chem Inf Model, DOI://10.1021/ci500363p (2014)

Type I IFN induces binding of STAT1 to Bcl6: divergent roles of STAT family transcription factors in the T follicular helper cell genetic program Nakayamada, S; Poholek, AC; Lu, KT et al. J. Immunol., DOI://10.4049/jimmunol.1300675 (2014)
Promoter-bound p300 complexes facilitate post-mitotic transmission of transcriptional memory Wong, MM; Byun, JS; Sacta, M; Jin, Q; Baek, S; Gardner, K; PLoS ONE, DOI://10.1371/journal.pone.0099989 (2014)
Telomere attrition and candidate gene mutations preceding monosomy 7 in aplastic anemia. Dumitriu B, Feng X, Townsley DM, Ueda Y, Yoshizato T, Calado RT, Yang Y, Wakabayashi Y, Kajigaya S, Ogawa S, Zhu J, Young NS Blood, doi://10.1182/blood-2014-10-607572 (2014)
Polymorphism in Self-Assembly of Peptide-Based β-Hairpin Contributes to Network Morphology and Hydrogel Mechanical Rigidity Yifat Miller, Buyong Ma, and Ruth Nussinov J. Phys. Chem. B, DOI: 10.1021/jp511485n (2014)
Prospective Associations of Coronary Heart Disease Loci in African Americans Using the MetaboChip: The PAGE Study Nora Franceschini, Yijuan Hu, Alex P. Reiner, et al. PLoS One, DOI: 10.1371/journal.pone.0113203 (2014)
Behçet disease-associated MHC class I residues implicate antigen binding and regulation of cell-mediated cytotoxicity. Ombrello MJ, Kirino Y, de Bakker PI, Gül A, Kastner DL, Remmers EF PNAS, doi: 10.1073/pnas.1406575111 (2014)

Integrated transcriptome analysis of mouse spermatogenesis Margolin G, Khil PP, Kim J, Bellani MA, Camerini-Otero RD BMC Genomics, doi: 10.1186/1471-2164-15-39 (2014)
Integromic Analysis of Genetic Variation and Gene Expression Identifies Networks for Cardiovascular Disease Phenotypes Chen Yao, Brian H. Chen, Roby Joehanes, et al. Circulation, doi: 10.1161/CIRCULATIONAHA.114.010696 (2014)
Sex- and Tissue-Specific Functions of Drosophila Doublesex Transcription Factor Target Genes Clough E, Jimenez E, Kim YA, Whitworth C, Neville MC, Hempel LU, Pavlou HJ, Chen ZX, Sturgill D, Dale RK, Smith HE, Przytycka TM, Goodwin SF, Van Doren M, Oliver B Dev. Cell, doi: 10.1016/j.devcel.2014.11.021 (2014)
Leveraging Local identity-by-descent increases the power of Case/Control GWAS with Related Individuals Joshua N Sampson, Bill Wheeler, Peng Li, Jianxin Shi Ann Appl Stat. 8(2):974-998. (2014)
Genome sequencing accuracy by RCA-seq versus long PCR template cloning and sequencing in identification of human papillomavirus type 58 Wang X, Li Y, Ni T, Xie X, Zhu J, Zheng ZM Cell Biosci. , doi: 10.1186/2045-3701-4-5 (2014)
Complex interactions of transcription factors in mediating cytokine biology in T cells Li P, Spolski R, Liao W, Leonard WJ. Immunol Rev, doi: 10.1111/imr.12199. (2014)

Opposing actions of IL-2 and IL-21 on Th9 differentiation correlate with their differential regulation of BCL6 expression Liao W, Spolski R, Li P, Du N, West EE, Ren M, Mitra S, Leonard WJ. PNAS, doi: 10.1073/pnas.1301138111 (2014)
Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo. Rudicell RS1, Kwon YD, Ko SY et al. Journal of Virology, doi: 10.1128/JVI.02213-14 (2014)
High Accuracy of Karplus Equations for Relating Three-Bond J Couplings to Protein Backbone Torsion Angles Fang Li, Jung Ho Lee, Alexander Grishaev, Jinfa Ying and Ad Bax Eur. J. Chem. Phys. Chem. , DOI: 10.1002/cphc.201402704 (2014)
Challenges and solutions for gene identification in the presence of familial locus heterogeneity Atteeq U Rehman, Regie Lyn P Santos-Cortez et al. Eur. J. Human Genetics, doi: 10.1038/ejhg.2014.266 (2014)
Linear Energy Relationships in Ground State Proton Transfer and Excited State Proton-Coupled Electron Transfer Ana-Patricia Gàmiz-Hernàndez , Artiom Magomedov , Gerhard Hummer , and Ville R. I. Kaila J. Phys. Chem. B, DOI: 10.1021/jp508790n (2014)
B Cell Super-Enhancers and Regulatory Clusters Recruit AID Tumorigenic Activity Jason Qian, Qiao Wang, Marei Dose et al. Cell, doi:10.1016/j.cell.2014.11.013 (2014)

Free energies from dynamic weighted histogram analysis using unbiased Markov state model Edina Rosta and Gerhard Hummer J. Chem. Theory Comput., DOI: 10.1021/ct500719p (2014)
High-resolution genome-wide DNA methylation maps of mouse primary female dermal fibroblasts and keratinocytes Raghunath Chatterjee, Ximiao He, Di Huang, Peter Fitzgerald, Andrew Smith and Charles Vinson Epigenetics and Chromatin, doi:10.1186/1756-8935-7-35 (2014)
Nucleosomes are enriched at the boundaries of hypomethylated regions (HMRs) in mouse dermal fibroblasts and keratinocytes Ximiao He, Raghunath Chatterjee, Desiree Tillo, Andrew Smith, Peter FitzGerald and Charles Vinson Epigenetics and Chromatin, doi:10.1186/1756-8935-7-34 (2014)
Genetic diversity is a predictor of mortality in humans Bihlmeyer NA, Brody JA, et al. BMC Genetics, doi:10.1186/s12863-014-0159-7 (2014)
TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4(+) T cell fate and interact with Runx3 to silence Cd4 in CD8(+) T cells Steinke FC, Yu S, Zhou X, He B, Yang W, Zhou B, Kawamoto H, Zhu J, Tan K8, Xue HH Naturesteinc Immunol. , doi: 10.1038/ni.2897. (2014)
Brain Structural Substrates of Reward Dependence during Behavioral Performance Dayan E, Hamann JM, Averbeck BB, Cohen LG J. Neurosci. , doi: 10.1523/JNEUROSCI.3141-14.2014 (2014)

Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2 Zhou Q, Yang D, Ombrello AK, et al. N. Engl. J. Med. , doi: 10.1056/NEJMoa1307361 (2014)
Modern perspectives on numerical modeling of cardiac pacemaker cell Maltsev VA, Yaniv Y, Maltsev AV, Stern MD, Lakatta EG J. Pharmacological Sci. , doi://10.1254/jphs.13R04CR (2014)
Risk estimation using probability machines. Dasgupta A1, Szymczak S, Moore JH, Bailey-Wilson JE, Malley JD BioData Min. , doi: 10.1186/1756-0381-7-2. (2014)
Rbfox3 controls the biogenesis of a subset of microRNAs Kim KK, Yang Y, Zhu J, Adelstein RS, Kawamoto S. Nat Struct Mol Biol., doi: 10.1038/nsmb.2892 (2014)
Bayesian analysis of individual electron microscopy images: Towards structures of dynamic and heterogeneous biomolecular assemblies Pilar Cossio and Gerhard Hummer J Struct Biol. , doi: 10.1016/j.jsb.2013.10.006 (2014)
Valence-specific effects of BDNF Val66Met polymorphism on dopaminergic stress and reward processing in humans Peciña M, Martìnez-Jauand M, Love T, Heffernan J, Montoya P, Hodgkinson C, Stohler CS, Goldman D, Zubieta JK. J. Neurosci., doi: 10.1523/JNEUROSCI.2152-13 (2014)
Comparative phosphoproteomic analysis of mammalian glomeruli reveals conserved podocin C-terminal phosphorylation as a determinant of slit diaphragm complex architecture Markus M. Rinschen, Caroline Pahmeyer, Trairak Pisitkun, Nicole Schnell, Xiongwu Wu, Martina Maa, Malte P. Bartram, Tobias Lamkemeyer, Bernhard Schermer, Thomas Benzing andPaul T. Brinkkoetter Proteomics, DOI: 10.1002/pmic.201400235 (2014)
A Systems Genetics Approach Identifies CXCL14, ITGAX, and LPCAT2 as Novel Aggressive Prostate Cancer Susceptibility Genes Kendra A. Williams, Minnkyong Lee, Ying Hu et al. PLoS Genetics, doi: 10.1371/journal.pgen.1004809 (2014)
Charge Neutralization of the Central Lysine Cluster in Prion Protein (PrP) Promotes PrPSc-Like Folding of Recombinant PrP Amyloids Bradley R. Groveman, Allison Kraus, Lynne D. Raymond, Michael A. Dolan, Kelsie J. Anson, David W. Dorward and Byron Caughey J. Biol. Chem. , doi: 10.1074/jbc.M114.619627 (2014)
Pathogenic Ischemic Stroke Phenotypes in the NINDS-Stroke Genetics Network Hakan Ay, Ethem Murat Arsava et al. Stroke, doi: 10.1161/STROKEAHA.114.007362 (2014)
Variant GADL1 and response to lithium in bipolar I disorder Consortium on Lithium Genetics, Hou L, Heilbronner U, Rietschel M, Kato T, Kuo PH, McMahon FJ, Schulze TG. N. Engl. J. Med. , doi: 10.1056/NEJMc1401817#SA4 (2014)
Investigation of the interactions between the EphB2 receptor and SNEW peptide variants Buyong Ma, Stephanie Kolb, Michael Diprima, Molleshree Karna, Giovanna Tosato, Qiqi Yang, Qiang Huang, and Ruth Nussinov Growth Factors, DOI: 10.3109/08977194.2014.985786 (2014)

Self-assembled monolayers improve protein distribution on holey carbon cryo-EM supports Joel R. Meyerson, Prashant Rao, Janesh Kumar, Sagar Chittori, Soojay Banerjee, Jason Pierson, Mark L. Mayer & Sriram Subramaniam Nature, doi:10.1038/srep07084 (2014)
Diversity and dynamics of the Drosophila transcriptome. Brown JB, Boley N, Eisman R, May GE et al Nature, doi:10.1038/nature12962 (2014)
Database of osmoregulated proteins in mammalian cells Cameron R. Grady , Mark A. Knepper , Maurice B. Burg , Joan D. Ferraris Physiological Reports, DOI: 10.14814/phy2.12180 (2014)
Simple subgroup approximations to optimal treatment regimes from randomized clinical trial data Jared C. Foster, Jeremy M.G. Taylor, Niko Kaciroti and Bin Nan Biostatistics, doi: 10.1093/biostatistics/kxu049 (2014)
Mitochondrial DNA Sequence Variation Associated With Peripheral Nerve Function in the Elderly Shana M. Katzman, Elsa S. Strotmeyer, Michael A. Nalls et al. J. Gerontology A, doi: 10.1093/gerona/glu175 (2014)
Role of solvation in pressure-induced helix stabilization Robert B. Best, Cayla Miller and Jeetain Mittal J. Chem. Physics, doi:///10.1063/1.4901112 (2014)

Mass spectrometry based protein identification with accurate statistical significance assignment Gelio Alves and Yi-Kuo Yu Bioinformatics, doi: 10.1093/bioinformatics/btu717 (2014)
Modeling vocalization with ECoG cortical activity recorded during vocal production in the macaque monkey Makoto Fukushima, Richard C Saunders, Naotaka Fujii, Bruno B Averbeck, Mortimer Mishkin Engineering in Medicine and Biology, DOI://10.1109/EMBC.2014.6945188 (2014)
DNA recombination. Recombination initiation maps of individual human genomes Pratto, F; Brick, K; Khil, P; Smagulova, F; Petukhova, GV; Camerini-Otero, RD; Science, DOI://10.1126/science.1256442 (2014)
Development and Implementation of (Q)SAR Modeling Within the CHARMMing Web-User Interface Iwona E. Weidlich, Yuri Pevzner, Benjamin T. Miller, Igor V. Filippov, H. Lee Woodcock, and Bernard R. Brooks J. Comp. Chem., DOI: 10.1002/jcc.23765 (2014)
Master Regulators, Regulatory Networks, and Pathways of Glioblastoma Subtypes Serdar Bozdag, Aiguo Li, Mehmet Baysan, and Howard A Fine Cancer Informatics, doi: 10.4137/CIN.S14027 (2014)
Variants associated with type 2 diabetes identified by the transethnic meta-analysis study: assessment in American Indians and evidence for a new signal in LPP Nair AK, Muller YL, McLean NA, Abdussamad M, Piaggi P, Kobes S, Weil EJ, Curtis JM, Nelson RG, Knowler WC, Hanson RL, Baier LJ Diabetologia, doi: 10.1007/s00125-014-3351-4 (2014)

DLX3 regulates bone mass by targeting genes supporting osteoblast differentiation and mineral homeostasis in vivo Isaac J, Erthal J, Gordon J, Duverger O, Sun HW, Lichtler AC, Stein GS, Lian JB, Morasso MI Cell Death Differ. , doi: 10.1038/cdd.2014.82 (2014)
Human syndromes of immunodeficiency and dysregulation are characterized by distinct defects in T-cell receptor repertoire development. Yu X, Almeida JR2, Darko S et al. J Allergy Clin Immunol., doi: 10.1016/j.jaci.2013.11.018. (2014)
Autosomal recessive phosphoglucomutase 3 (PGM3) mutations link glycosylation defects to atopy, immune deficiency, autoimmunity, and neurocognitive impairment. Zhang Y, Yu X, Ichikawa M et al. J Allergy Clin Immunol. , doi: 10.1016/j.jaci.2014.02.013 (2014)
FAAH selectively influences placebo effects Peciña M, Martìnez-Jauand M, Hodgkinson C, Stohler CS, Goldman D, Zubieta JK Molecular Psychiatry, doi: 10.1038/mp.2013.124 (2014)
Essential dynamics analysis captures the concerted motion of the integrin-binding site in jerdostatin, an RTS disintegrin Luisa Calvanese, Lucia Falcigno andGabriella D'Auria Biopolymers, DOI: 10.1002/bip.22578 (2014)
Role of the Fast Kinetics of Pyroglutamate-Modified Amyloid-β Oligomers in Membrane Binding and Membrane Permeability Joon Lee, Alan L. Gillman, Hyunbum Jang, Srinivasan Ramachandran, Bruce L. Kagan, Ruth Nussinov, Fernando Teran Arce Biochemistry, doi: 10.1021/bi500587p (2014)
Pathogenic Properties of Alzheimer's β-Amyloid Identified from Structure-Property Patient-Phenotype Correlations Manish K. Tiwari and Kasper P. Kepp Dalt. Transac. , DOI: 10.1039/C4DT03122A (2014)
Using fMRI to decode true thoughts independent of intention to conceal Yang Z, Huang Z, Gonzalez-Castillo J, Dai R, Northoff G, Bandettini P NeuroImage, doi: 10.1016/j.neuroimage.2014.05.034 (2014)
Probing the Flexibility of Tropomyosin and Its Binding to Filamentous Actin Using Molecular Dynamics Simulations Wenjun Zheng, Bipasha Barua, and Sarah E. Hitchcock-DeGregori Biophysical J. , doi: 10.1016/j.bpj.2013.09.003 (2014)
Cohesin-dependent globules and heterochromatin shape 3D genome architecture in S. pombe Takeshi Mizuguchi, Geoffrey Fudenberg, Sameet Mehta, Jon-Matthew Belton, Nitika Taneja, Hernan Diego Folco, Peter FitzGerald, Job Dekker, Leonid Mirny, Jemima Barrowman & Shiv I. S. Grewal Nature, doi:10.1038/nature13833 (2014)
Direct Evidence for a Peroxide Intermediate and a Reactive Enzyme-Substrate-Dioxygen Configuration in a Cofactor-free Oxidase Soi Bui, David von Stetten, Pablo G. Jambrina, Thierry Prangé, Nathalie Colloc'h, Daniele de Sanctis, Antoine Royant, Edina Rosta and Roberto A. Steiner Angewandte Chemie, DOI: 10.1002/anie.201405485 (2014)
Sequential monte carlo tracking of the marginal artery by multiple cue fusion and random forest regression Kevin M. Cherry, Brandon Peplinski, Lauren Kim, Shijun Wang, Le Lu, Weidong Zhang, Jianfei Liu, Zhuoshi Wei, Ronald M. Summers Medical Image Analysis, DOI: 10.1016/j.media.2014.09.006 (2014)

Balanced Protein-Water Interactions Improve Properties of Disordered Proteins and Non-Specific Protein Association Robert B. Best, Wenwei Zheng, and Jeetain Mittal J. Chem. Theory and Computation, DOI: 10.1021/ct500569b (2014)
Phactr3/Scapinin, a Member of Protein Phosphatase 1 and Actin Regulator (Phactr) Family, Interacts with the Plasma Membrane via Basic and Hydrophobic Residues in the N-Terminus Akihiro Itoh, Atsushi Uchiyama, Shunichiro Taniguchi, and Junji Sagara PLoS One, doi: 10.1371/journal.pone.0113289 (2014)
Crystal structure of a c-di-AMP riboswitch reveals an internally pseudo-dimeric RNA Christopher P Jones andAdrian R Ferr�-D'Amarè EMBO J., DOI: 10.15252/embj.201489209 (2014)
A system for multilocus chromosomal integration and transformation-free selection marker rescue Michael S. Siddiqui, Atri Choksi andChristina D. Smolke Yeast Research, DOI: 10.1111/1567-1364.12210 (2014)
Biogeography and individuality shape function in the human skin metagenome Julia Oh, Allyson L. Byrd, Clay Deming, Sean Conlan, NISC Comparative Sequencing Program, Heidi H. Kong & Julia A. Segre Nature, doi:10.1038/nature13786 (2014)
Combining one-sample confidence procedures for inference in the two-sample case Michael P. Fay, Michael A. Proschan andErica Brittain Biometrics, DOI: 10.1111/biom.12231 (2014)

Certain adenylated non-coding RNAs, including 5' leader sequences of primary microRNA transcripts, accumulate in mouse cells following depletion of the RNA helicase MTR4 Dorweiler JE, Ni T, Zhu J, Munroe SH, Anderson JT PLoS One, doi: 10.1371/journal.pone.0099430. (2014)
miR-191 and miR-135 are required for long-lasting spine remodelling associated with synaptic long-term depression Hu Z, Yu D, Gu QH, Yang Y, Tu K, Zhu J, Li Z Nature Communications, doi: 10.1038/ncomms4263 (2014)
Determination of the allelic frequency in Smith-Lemli-Opitz syndrome by analysis of massively parallel sequencing data sets Cross JL, Iben J, Simpson CL, Thurm A, Swedo S, Tierney E, Bailey-Wilson JE, Biesecker LG, Porter FD, Wassif CA Clin. Genet. , doi: 10.1111/cge.12425. (2014)
Activated STING in a Vascular and Pulmonary Syndrome Liu Y, Jesus AA, Marrero B et al. New England J. Medicine, doi: 10.1056/NEJMoa1312625. (2014)
An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome Scott W Canna, Adriana A de Jesus, Sushanth Gouni, Stephen R Brooks, Bernadette Marrero, Yin Liu, Michael A DiMattia, Kristien J M Zaal, Gina A Montealegre Sanchez, Hanna Kim, Dawn Chapelle, Nicole Plass, Yan Huang, Alejandro V Villarino, Angelique Biancotto, Thomas A Fleisher, Joseph A Duncan, John J O'Shea, Susanne Benseler, Alexei Grom, Zuoming Deng, Ronald M Laxer & Raphaela Goldbach-Mansky Nature Genetics, doi:10.1038/ng.3089 (2014)
DNA copy number evolution in Drosophila cell lines Hangnoh Lee, C Joel McManus et al. Genome Biology, doi:10.1186/gb-2014-15-8-r70 (2014)

Joint analysis of longitudinal and survival data measured on nested timescales by using shared parameter models: an application to fecundity data Alexander C. McLain, Rajeshwari Sundaram and Germaine M. Buck Louis Applied Statistics, DOI: 10.1111/rssc.12075 (2014)
DNase Footprint Signatures Are Dictated by Factor Dynamics and DNA Sequence Myong-Hee Sung, Michael J. Guertin, Songjoon Baek, Gordon L. Hager Molecular Cell, DOI: 10.1016/j.molcel.2014.08.016 (2014)
Correcting for the free energy costs of bond or angle constraints in molecular dynamics simulations Gerhard König, , Bernard R. Brooks Biochim. et Biophys. Acta, DOI: 10.1016/j.bbagen.2014.09.001 (2014)
Genetic polymorphisms in the 9p21 region associated with risk of multiple cancers Wen-Qing Li, Ruth M. Pfeiffer, Paula L. Hyland, Jianxin Shi, Fangyi Gu, Zhaoming Wang, Samsiddhi Bhattacharjee, Jun Luo, Xiaoqin Xiong, Meredith Yeager, Xiang Deng, Nan Hu, Philip R. Taylor, Demetrius Albanes, Neil E. Caporaso, Susan M. Gapstur, Laufey Amundadottir, Stephen J. Chanock, Nilanjan Chatterjee, Maria Teresa Landi, Margaret A. Tucker, Alisa M. Goldstein and Xiaohong R. Yang Carcinogenesis, doi: 10.1093/carcin/bgu203 (2014)
Enhanced expression of the codon-optimized exo-inulinase gene from the yeast Meyerozyma guilliermondii in Saccharomyces sp. W0 and bioethanol production from inulin Guang-Lei Liu, Ge-Yi Fu, Zhe Chi and Zhen-Ming Chi Bioenergy and Biofuels, doi://10.1007/s00253-014-6079-7 (2014)
Efficiently computing pathway free energies: New approaches based on chain-of-replica and Non-Boltzmann Bennett reweighting schemes Phillip S. Hudson, Justin K. White, Fiona L. Kearns, Milan Hodoscek, Stefan Boresch, H. Lee Woodcock Biochim. et Biophys. Acta, DOI: 10.1016/j.bbagen.2014.09.016 (2014)

Common genetic variation in and near the melanocortin 4 receptor gene (MC4R) is associated with body mass index in American Indian adults and children. Muller YL, Thearle MS, Piaggi P, Hanson RL, Hoffman D, Gene B, Mahkee D, Huang K, Kobes S, Votruba S, Knowler WC, Bogardus C, Baier LJ. Human Genetics, doi://10.1007/s00439-014-1477-6 (2014)
Neuronal or hemodynamic? Grappling with the functional MRI signal Bandettini PA Brain Connect, doi: 10.1089/brain.2014.0288. (2014)
A knowledge base of vasopressin actions in the kidney Akshay Sanghi, Matthew Zaringhalam, Callan C Corcoran, Fahad Saeed, Jason D. Hoffert, Pablo C Sandoval, Trairak Pisitkun, Mark A. Knepper Am. J. Physiol. - Renal Physiol., DOI: 10.1152/ajprenal.00012.2014 (2014)
Generalized Functional Linear Models for Gene-Based Case-Control Association Studies Ruzong Fan, Yifan Wang, James L. Mills, Tonia C. Carter, Iryna Lobach, Alexander F. Wilson, Joan E. Bailey-Wilson, Daniel E. Weeks and Momiao Xiong Genetic Epidemiology, DOI: 10.1002/gepi.21840 (2014)
Conformational dynamics and aggregation behavior of piezoelectric diphenylalanine peptides in an external electric field Catherine M. Kelly, Thomas Northey, Kate Ryan, Bernard R. Brooks, Andrei Kholkin, Brian J. Rodriguez, Nicolae-Viorel Buchete Biophysical Chemistry, DOI: 10.1016/j.bpc.2014.08.009 (2014)
Free-Propagator Reweighting Integrator for Single-Particle Dynamics in Reaction-Diffusion Models of Heterogeneous Protein-Protein Interaction Systems Margaret Johnson and Gerhard Hummer Physical Review X, DOI: 10.1103/PhysRevX.4.031037 (2014)

metaseq: a Python package for integrative genome-wide analysis reveals relationships between chromatin insulators and associated nuclear mRNA Dale RK, Matzat LH, Lei EP Nucleic Acids Research, doi: 10.1093/nar/gku644 (2014)
Deletion of aryl hydrocarbon receptor AHR in mice leads to subretinal accumulation of microglia and RPE atrophy Soo-Young Kim, Hyun-Jin Yang, Yi-Sheng Chang, Jung-woong Kim, Matthew Brooks, Emily Y. Chew, Wai T. Wong, Robert Fariss, Rivka Rachel, Tiziana Cogliati, Haohua Qian and Anand Swaroop Investigative Opthalmology and Visual Science, doi: 10.1167/iovs.14-15091 (2014)
Modeling longitudinal data with a random change point and no time-zero: Applications to inference and prediction of the labor curve Alexander C. McLain and Paul S. Albert Biometrics, DOI: 10.1111/biom.12218 (2014)
Molecular origins of internal friction effects on protein-folding rates de Sancho D, Sirur A, Best RB Nature Communications, doi: 10.1038/ncomms5307 (2014)
Design and rationale for a genome-wide association study of ischemic stroke subtypes James F. Meschia, Donna K. Arnett, Hakan Ay et al. Stroke, doi: 10.1161/STROKEAHA.113.001857 (2014)
Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations Chen Wu, Zhaoming Wang, Xin Song et al. Nature Genetics, doi:10.1038/ng.3064 (2014)

Systematic Genetic Analysis Identifies Cis-eQTL Target Genes Associated with Glioblastoma Patient Survival Qing-Rong Chen, Ying Hu, Chunhua Yan, Kenneth Buetow, Daoud Meerzaman PLoS One, DOI: 10.1371/journal.pone.0105393 (2014)
Structural Insight into Tau Protein's Paradox of Intrinsically Disordered Behavior, Self-Acetylation Activity, and Aggregation Yin Luo, Buyong Ma, Ruth Nussinov, and Guanghong Wei J. Phys. Chem. Lett, DOI: 10.1021/jz501457f (2014)
Impaired corticopontocerebellar tracts underlie pseudobulbar affect in motor neuron disorders Mary Kay Floeter, Rohan Katipally, Meredith P. Kim, Olivia Schanz, Matthew Stephen, Laura Danielian, Tianxia Wu, Edward D. Huey, and Avner Meoded Neurology, doi: 10.1212/WNL.0000000000000693 (2014)
Programmable Nanoscaffolds that Control Ligand Display to a G Protein Coupled-Receptor in Membranes allow Dissection of Multivalent Effects Andrew V. Dix, Steven M Moss, Khai Phan, Travis Hoppe, Silvia Paoletta, Eszter Kozma, Zhan-Guo Gao, Stewart R. Durell, Kenneth A. Jacobson, and Daniel H. Appella J. Am. Chem. Soc. , DOI: 10.1021/ja504288s (2014)
Identification of Three Noncontiguous Regions on Bacillus anthracis Plasmid pXO1 That Are Important for Its Maintenance Andrei P. Pomerantsev, Zanetta Chang, Catherine Rappole and Stephen H. Leppla J. Bacteriology, doi: 10.1128/JB.01747-14 (2014)
Random Single Amino Acid Deletion Sampling Unveils Structural Tolerance and the Benefits of Helical Registry Shift on GFP Folding and Structure James A.J. Arpino, Samuel C. Reddington, Lisa M. Halliwell, Pierre J. Rizkallah, D. Dafydd Jones Structure, DOI: 10.1016/j.str.2014.03.014 (2014)

Optimizing area under the ROC curve using semi-supervised learning Shijun Wang, Diana Li, Nicholas Petrick, Berkman Sahiner, Marius George Linguraru, Ronald M. Summers Pattern Recognition, DOI: 10.1016/j.patcog.2014.07.025 (2014)
Trans-ethnic Meta-analysis of White Blood Cell Phenotypes MF Keller, AP Reiner et al. Human Molecular Genetics, doi://10.1093/hmg/ddu401 (2014)
NeuroX, a Fast and Efficient Genotyping Platform for Investigation of Neurodegenerative Diseases Mike A. Nalls, Jose Bras, Dena G. Hernandez, et al. Neurobiology of Aging, DOI: 10.1016/j.neurobiolaging.2014.07.028 (2014)
A Novel MMP12 Locus Is Associated with Large Artery Atherosclerotic Stroke Using a Genome-Wide Age-at-Onset Informed Approach Traylor M et al. PLoS Genetics, DOI: 10.1371/journal.pgen.1004469 (2014)
Structural mechanism of glutamate receptor activation and desensitization Joel R. Meyerson, Janesh Kumar, Sagar Chittori, Prashant Rao, Jason Pierson, Alberto Bartesaghi, Mark L. Mayer & Sriram Subramaniam Nature, doi:10.1038/nature13603 (2014)
Structure of β-galactosidase at 3.2-Å resolution obtained by cryo-electron microscopy Alberto Bartesaghi, Doreen Matthies, Soojay Banerjee, Alan Merk, and Sriram Subramaniam PNAS, doi://10.1073/pnas.1402809111 (2014)

Dynamics differentiate between active and inactive inteins Melissa Cronin, Michael J. Coolbaug, David Nellis, Jianwei Zhu, David W. Wood, Ruth Nussinov, Buyong Ma Eur. J. Med. Chem., DOI: 10.1016/j.ejmech.2014.07.094 (2014)
Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease MA Nalls, N Pankratz, CM Lill et al. Nature Genetics, doi:10.1038/ng.3043 (2014)
Differentiating BOLD and non-BOLD signals in fMRI time series from anesthetized rats using multi-echo EPI at 11.7T Prantik Kundu, Mathieu D. Santin, Peter A. Bandettini, Edward T. Bullmore, Alexandra Petiet NeuroImage, DOI: 10.1016/j.neuroimage.2014.07.025 (2014)
A robust association test for detecting genetic variants with heterogeneous effects Kai Yu and Han Zhang Biostatistics, doi: 10.1093/biostatistics/kxu036 (2014)
Image-Guided Synthesis Reveals Potent Blood-Brain Barrier Permeable Histone Deacetylase Inhibitors Young Jun Seo, Yeona Kang, Lisa Muench, Alicia Reid, Shannon Caesar, Logan Jean, Florence Wagner, Edward Holson, Stephen J. Haggarty, Philipp Weiss, Payton King, Pauline Carter, Nora D. Volkow, Joanna S. Fowler, Jacob M. Hooker, and Sung Won Kim ACS Chemical Neurosciene, DOI: 10.1021/cn500021p (2014)
Structural Basis of hAT Transposon End Recognition by Hermes, an Octameric DNA Transposase from Musca domestica Alison B. Hickman, Hosam E. Ewis, Xianghong Li, Joshua A. Knapp, Thomas Laver, Anna-Louise Doss, Gökhan Tolun, Alasdair C. Steven, Alexander Grishaev, Ad Bax, Peter W. Atkinson, Nancy L. Craig, Fred Dyda Cell, DOI: 10.1016/j.cell.2014.05.037 (2014)

Parallel in-register intermolecular β-sheet architectures for prion seeded PrP amyloids Bradley R. Groveman, Michael A. Dolan, Lara M. Taubner, Allison Kraus, Reed B. Wickner and Byron Caughey J. Biol. Chem. , doi: 10.1074/jbc.M114.578344 (2014)
The Three Mycobacterium Tuberculosis Antigen 85 Isoforms have Unique Substrates and Activities Determined by Non-active Site Regions Keriann M. Backus, Michael A. Dolan, Conor S. Barry, Maju Joe, Peter McPhie, Helena I.M. Boshoff, Todd L. Lowary, Benjamin G. Davis and Clifton E. Barry III J. Biol. Chem. , doi: 10.1074/jbc.M114.581579 (2014)
Accounting for length-bias and selection effects in estimating the distribution of menstrual cycle length Kirsten J. Lum, Rajeshwari Sundaram, Thomas A. Louis Biostatistics, doi: 10.1093/biostatistics/kxu035 (2014)
Genome-Wide Analysis of the Heritability of Amyotrophic Lateral Sclerosis MF Keller, L Ferrucci, AB Singleton et al. JAMA Neurology, doi:10.1001/jamaneurol.2014.1184 (2014)
The Genomic Landscape of the Ewing Sarcoma Family of Tumors Reveals Recurrent STAG2 Mutation Andrew S. Brohl, David A. Solomon, Wendy Chang et al. PLoS Genetics, DOI: 10.1371/journal.pgen.1004475 (2014)
Spatial Localization of the Ebola Virus Glycoprotein Mucin-Like Domain Determined by Cryo-Electron Tomography Erin E. H. Tran, James A. Simmons, Alberto Bartesaghi, Charles J. Shoemaker, Elizabeth Nelson, Judith M. White and Sriram Subramaniam J. Virology, doi: 10.1128/JVI.00870-14 (2014)

Integrated Design of Antibodies for Systems Biology Using AbDesigner Trairak Pisitkun, Patrick Dummer, Poorichaya Somparn, Nattiya Hirankarn, Jeffrey B Kopp and Mark A Knepper Proteomics and Bioinformatics, doi://10.4172/jpb.1000307 (2014)
Parkinson's disease in GTP cyclohydrolase 1 mutation carriers Niccoló E. Mencacci, Ioannis U. Isaias, Martin M. Reich et al. Brain, doi: 10.1093/brain/awu179 (2014)
Brain Network Informed Subject Community Detection In Early-Onset Schizophrenia Zhi Yang, Yong Xu, Ting Xu, Colin W. Hoy, Daniel A. Handwerker, Gang Chen, Georg Northoff, Xi-Nian Zuo & Peter A. Bandettini Scientific Reports, doi:10.1038/srep05549 (2014)
Role of Albumin in the Formation and Stabilization of Nanoparticle Aggregates in Serum Studied by Continuous Photon Correlation Spectroscopy and Multiscale Computer Simulations Ashwinkumar A. Bhirde , Sergio A Hassan , Erick Harr , and Xiaoyuan Chen J. Phys. Chem. C, DOI: 10.1021/jp5034068 (2014)
Comparative validation of the D. melanogaster modENCODE transcriptome annotation ZX Chen, D Sturgill, J Qu, H Jiang et al. Genome Research, doi://10.1101/gr.159384.113 (2014)
Phosphoproteomic Analysis Reveals Regulatory Mechanisms at the Kidney Filtration Barrier Markus M. Rinschen, Xiongwu Wu, Tim K�nig, Trairak Pisitkun, Henning Hagmann, Caroline Pahmeyer, Tobias Lamkemeyer, Priyanka Kohli, Nicole Schnell, Bernhard Schermer, Stuart Dryer, Bernard R. Brooks, Pedro Beltrao, Marcus Krueger, Paul T. Brinkkoetter, Thomas Benzing J Am Soc Nephrol., doi: 10.1681/ASN.2013070760 (2014)

Common genetic variation in the glucokinase gene (GCK) is associated with type 2 diabetes and rates of carbohydrate oxidation and energy expenditure Muller YL, Piaggi P, Hoffman D, Huang K, Gene B, Kobes S, Thearle MS, Knowler WC, Hanson RL, Baier LJ, Bogardus C Diabetologia, doi: 10.1007/s00125-014-3234-8 (2014)
Task Dependence, Tissue Specificity, and Spatial Distribution of Widespread Activations in Large Single-Subject Functional MRI Datasets at 7T Javier Gonzalez-Castillo, Colin W. Hoy, Daniel A. Handwerker, Vinai Roopchansingh, Souheil J. Inati, Ziad S. Saad, Robert W. Cox and Peter A. Bandettini Cerebral Cortex, doi://10.1093/cercor/bhu148 (2014)
Corpus Callosum Size Is Highly Heritable in Humans, and May Reflect Distinct Genetic Influences on Ventral and Rostral Regions Girma Woldehawariat, Pedro E. Martinez, Peter Hauser, David M. Hoover, Wayne W. C. Drevets, Francis J. McMahon PLoS One, DOI: 10.1371/journal.pone.0099980 (2014)
Thermodynamic, Dynamic and Solvational Properties of PDEδ Binding to Farnesylated Cystein: A Model Study for Uncovering the Molecular Mechanism of PDEδ Interaction with Prenylated Proteins S. Suladze, S. Ismail, and R. Winter J. Phys. Chem. B, DOI: 10.1021/jp411466r (2014)
Inhibition of Paracoccidioides lutzii Pb01 Isocitrate Lyase by the Natural Compound Argentilactone and Its Semi-Synthetic Derivatives Renata Silva do Prado, Ricardo Justino Alves et al PLoS One, DOI: 10.1371/journal.pone.0094832 (2014)
Genome-wide association analysis identifies six new loci associated with forced vital capacity Loth DW, Artigas MS, Gharib SA et al. Nat Genet., doi: 10.1038/ng.3011. (2014)

Introductions and evolution of human-origin seasonal influenza A viruses in multinational swine populations Martha I. Nelson, David E. Wentworth, Marie R. Culhane, Amy L. Vincent, Cecile Viboud, Matthew P. LaPointe, Xudong Lin, Edward C. Holmes and Susan E. Detmer J. Virology, doi: 10.1128/JVI.01080-14 (2014)
The evolutionary dynamics of influenza A and B viruses in the tropical city of Managua, Nicaragua Martha I. Nelson, Angel Balmaseda, Guillermina Kuan, Saira Saborio, Xudong Lin, Rebecca A. Halpin, Timothy B. Stockwell, David E. Wentworth, Eva Harris, Aubree Gordon Virology, DOI: 10.1016/j.virol.2014.05.025 (2014)
Highly efficient production of peptides: N-glycosidase F for N-glycomics analysis Ling Hua, b, Xin Gao, Xiaopan Yang, Deyou Wan, Chunpeng He, Jiyue Cao, Haifeng Song Protein Expression and Purification, DOI: 10.1016/j.pep.2014.02.004 (2014)
Approaches to retrospective sampling for longitudinal transition regression models Sally Hunsberger, Paul S. Albert, and Marie Thoma Statistics and Its Interface 7:75-85, doi://10.4310/SII.2014.v7.n1.a9 (2014)
Identification and Characterization of Seminal Fluid Proteins in the Asian Tiger Mosquito, Aedes albopictus Kathryn E. Boes, José M. C. Ribeiro, Alex Wong, Laura C. Harrington, Mariana F. Wolfner, and Laura K. Sirot PLoS Neglected Tropical Diseases, doi: 10.1371/journal.pntd.0002946 (2014)
Marginal analysis of measurement agreement among multiple raters with non-ignorable missing ratings Zhen Chen and Yunlong Xie Statistics and Its Interface 7:113-120, doiL//10.4310/SII.2014.v7.n1.a12 (2014)

Linear mixed models for multiple outcomes using extended multivariate skew-t distributions Binbing Yu, A. James O'Malley, and Pulak Ghosh Statistics and Its Interface 7:101-111, doi://10.4310/SII.2014.v7.n1.a11 (2014)
Matched longitudinal analysis of biomarkers associated with survival Lori E. Dodd, Reed F. Johnson, Joseph E. Blaney and Dean Follmann Clinical & Vaccine Immunology, doi: 10.1128/CVI.00252-14 (2014)
Frontotemporal dementia and its subtypes: a genome-wide association study Ferrari R, Hernandez D, Nalls M et al. The Lancet Neurology, DOI: 10.1016/S1474-4422(14)70065-1 (2014)
Activity and Architecture of Pyroglutamate Modified Amyloid-β (AβpE3-42) Pores Alan L Gillman , Hyunbum Jang , Joon Lee , Srinivasan Ramachandran , Bruce L. Kagan , Ruth Nussinov , and Fernando Teran Arce J. Phys. Chem. B, DOI: 10.1021/jp5040954 (2014)
Computational Tools and Algorithms for Designing Customized Synthetic Genes Nathan Gould, Oliver Hendy, and Dimitris Papamichail Front Bioeng Biotechnol, doi: 10.3389/fbioe.2014.00041 (2014)
Role of LDB1 in the transition from chromatin looping to transcription activation. Krivega I, Dale RK, Dean A. Genes Dev., doi: 10.1101/gad.239749.114 (2014)

Implicit treatment of solvent dispersion forces in protein simulations Sergio A Hassan Journal of Computational Chemistry, DOI: 10.1002/jcc.23655 (2014)
Conscious recall of different aspects of skill memory Sunbin Song & Leonardo G Cohen Frontiers in Behavioural Neuroscience, doi:10.3389/fnbeh.2014.00233 (2014)
A novel role of CDX1 in embryonic epicardial development Chu M, Wang L, Wang H, Shen T, Yang Y, Sun Y, Tang N, Ni T, Zhu J, Mailman RB, Wang Y PLoS One, doi: 10.1371/journal.pone.0103271 (2014)
Pre-fusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy Alberto Bartesaghi, Alan Merk, Mario J. Borgnia, Jacqueline L. S. Milne, and Sriram Subramaniam Nat Struct Mol Biol., doi: 10.1038/nsmb.2711 (2014)
Clinical correlates and genetic linkage of social and communication difficulties in families with obsessive-compulsive disorder: Results from the OCD Collaborative Genetics Study Samuels, J; Shugart, YY; Wang, Y et al. Am. J. Med. Genet. B Neuropsychiatr. Genet., DOI://10.1002/ajmg.b.32235 (2014)
The spatial structure of resting state connectivity stability on the scale of minutes Javier Gonzalez-Castillo, Daniel A Handwerker, Meghan E. Robinson, Colin Wier Hoy, Laura Cathleen Buchanan, Ziad S Saad and Peter A Bandettini Frontiers in Neuroscience, DOI://10.3389/fnins.2014.00138 (2014)

The RNA-binding protein Rumpelstiltskin antagonizes gypsy chromatin insulator function in a tissue-specific manner. King MR, Matzat LH, Dale RK, Lim SJ, Lei EP J. Cell. Sci., doi: 10.1242/jcs.151126 (2014)
Use of LC-MS/MS and Bayes' Theorem to Identify Protein Kinases That Phosphorylate Aquaporin-2 at Ser256 Davis Bradford, Viswanathan Raghuram, Justin L.L. Wilson, Chung-Lin Chou, Jason D. Hoffert, Mark A. Knepper, Trairak Pisitkun Am. J. Physiol. - Cell Physiol. , DOI: 10.1152/ajpcell.00377.2012 (2014)
Nill-Schiff base complex as an enzyme inhibitor of hen egg white lysozyme: a crystallographic and spectroscopic study Banabithi Koley Seth, Aurkie Ray, Sampa Biswas and Samita Basu Metallomics, DOI: 10.1039/C4MT00098F (2014)
Identification of the Genomic Insertion Site of Pmel-1 TCR α and β Transgenes by Next-Generation Sequencing Yun Ji, Natalie Abrams, Wei Zhu, Eddie Salinas, Zhiya Yu, Douglas C. Palmer, Parthav Jailwala, Zulmarie Franco, Rahul Roychoudhuri, Eric Stahlberg, Luca Gattinoni, Nicholas P. Restifo PLoS One, DOI: 10.1371/journal.pone.0096650 (2014)
Combination of longitudinal biomarkers in predicting binary events Danping Liu and Paul S Albert Biostatistics, doi: 10.1093/biostatistics/kxu020 (2014)
Rare missense variants in POT1 predispose to familial cutaneous malignant melanoma Shi J, Yang XR, Ballew B Nature Genetics, doi: 10.1038/ng.2941 (2014)

Pleiotropic genes for metabolic syndrome and inflammation Kraja AT, Chasman DI, North KE et al. Molecular Genetics & Metabolism, doi://10.1016/j.ymgme.2014.04.007 (2014)
Perturbation of nuclear spin polarizations in solid state NMR of nitroxide-doped samples by magic-angle spinning without microwaves Kent R. Thurber and Robert Tycko J. Chem. Phys. , DOI: 10.1063/1.4874341 (2014)
Chromosome fragility and the abnormal replication of the FMR1 locus in fragile X syndrome Yudkin, D; Hayward, BE; Aladjem, MI; Kumari, D; Usdin, K; Hum. Mol. Genet., DOI://10.1093/hmg/ddu006 (2014)
Rhythmic Bursting in the Pre-Bötzinger Complex: Mechanisms and Models Ilya A. Rybak, Yaroslav I. Molkov, Patrick E. Jasinski, Natalia A. Shevtsova, Jeffrey C. Smith Progress in Brain Research, doi://10.1016/B978-0-444-63274-6.00001-1 (2014)
Early targets of lithium in rat kidney inner medullary collecting duct include p38 and ERK1/2 Francesco Trepiccione, Trairak Pisitkun, Jason D Hoffert, Søren B Poulsen, Giovambattista Capasso, Søren Nielsen, Mark A Knepper, Robert A Fenton and Birgitte M Christensen Kidney International, doi: 10.1038/ki.2014.107 (2014)
Electrostatics, hydration, and proton transfer dynamics in the membrane domain of respiratory complex I Ville R. I. Kaila, Mârten Wikström and Gerhard Hummer PNAS, doi: 10.1073/pnas.1319156111 (2014)

Hierarchical clustering of ryanodine receptors enables emergence of a calcium clock in sinoatrial node cells Michael D. Stern, Larissa A. Maltseva, Magdalena Juhaszova, Steven J. Sollott, Edward G. Lakatta, and Victor A. Maltsev J. Gen. Physiol. , doi: 10.1085/jgp.201311123 (2014)
Conserved hydrogen-bonding network of P2 bis-tetrahydrofuran containing HIV-1 protease inhibitors (PI) with protease active site amino acid-backbone aid in their activity against PI-resistant HIV Ravikiran S. Yedidi, Harisha Garimella, Manabu Aoki, Hiromi Aoki, Darshan V. Desai, Simon B. Chang, David A. Davis, W. Sean Fyvie, Joshua D. Kaufman, David W. Smith, Debananda Das, Paul T. Wingfield, Kenji Maeda, Arun K. Ghosh and Hiroaki Mitsuya Antimicrob Agents Chemother., doi://10.1128/AAC.00107-14 (2014)
Non-invasive urinary metabolomic profiling identifies diagnostic and prognostic markers in lung cancer Ewy A Mathe, Andrew D Patterson, Majda Haznadar, Soumen K Manna, Kristopher W. Krausz, Elise D Bowman, Peter G. Shields, Jeffrey R. Idle, Philip B Smith, Katsuhiro Anami, Dickran Kazandjian, Emmanuel Hatzakis, Frank J Gonzalez, and Curtis C. Harris Cancer Res., doi:10.1158/0008-5472.CAN-14-0109 (2014)
Impact of subdomain D1 of the short form S1b of the human prolactin receptor on its inhibitory action on the function of the long form of the receptor induced by prolactin J.-H. Kang, S.A. Hassan, 1, P. Zhao, C.H. Tsai-Morris, M.L. Dufau Biochim. et Biophys. Acta, doi://10.1016/j.bbagen.2014.04.006 (2014)
A Fast and Powerful Tree-Based Association Test for Detecting Complex Joint Effects in Case-Control Studies Han Zhang, William Wheeler, Zhaoming Wang, Philip R. Taylor and Kai Yu Bioinformatics, doi://10.1093/bioinformatics/btu186 (2014)
Post-Translational Decrease in Respiratory Chain Proteins in the Polg Mutator Mouse Brain David N. Hauser, Allissa A. Dillman, Jinhui Ding, Yan Li, Mark R. Cookson PLoS One, DOI: 10.1371/journal.pone.0094646 (2014)

Studies on Inhibition of Respiratory Cytochrome bc1 Complex by the Fungicide Pyrimorph Suggest a Novel Inhibitory Mechanism Yu-Mei Xiao, Lothar Esser, Fei Zhou, Chang Li, Yi-Hui Zhou, Chang-An Yu, Zhao-Hai Qin, Di Xia PLoS One, DOI: 10.1371/journal.pone.0093765 (2014)
Regulation of a novel isoform of Receptor Expression Enhancing Protein REEP6 in rod photoreceptors by bZIP transcription factor NRL Hong Hao, Shobi Veleri, Bo Sun, Douglas S. Kim, Patrick W. Keeley, Jung-Woong Kim, Hyun-Jin Yang, Sharda P. Yadav, Souparnika H. Manjunath, Raman Sood, Paul Liu, Benjamin E. Reese and Anand Swaroop Human Molecular Genetics, doi: 10.1093/hmg/ddu143 (2014)
Distributed MRI reconstruction using gadgetron-based cloud computing Hui Xue, Souheil Inati, Thomas Sangild Sørensen, Peter Kellman and Michael S. Hansen Magnetic Resonance in Medicine, DOI: 10.1002/mrm.25213 (2014)
Hemoglobinopathic erythrocytes affect the intraerythrocytic multiplication of Plasmodium falciparum in vitro Svetlana Glushakova, Amanda Balaban, Philip G. McQueen, Rosane Coutinho, Jeffery L. Miller, Ralph Nossal, Rick M. Fairhurst, Joshua Zimmerberg J. Infectious Diseases, doi:10.1093/infdis/jiu203 (2014)
A potent anti-dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface Guntur Fibriansah, Joanne L Tan,Scott A Smith, Adamberage R Alwis, Thiam-Seng Ng, Victor A Kostyuchenko, Kristie D Ibarra, Jiaqi Wang, Eva Harris, Aravinda Silva, James E Crowe, and Shee-Mei Lok EMBO Molecular Medicine, doi: 10.1002/emmm.201303404 (2014)
A mixture of transition models for heterogeneous longitudinal ordinal data: with applications to longitudinal bacterial vaginosis data Kyeongmi Cheon, Marie E. Thoma, Xiangrong Kong and Paul S. Albert Statistics in Medicine, DOI: 10.1002/sim.6151 (2014)
Abdominal lymphadenopathy detection using random forest Kevin M. Cherry, Shijun Wang, Evrim B. Turkbey, Ronald M. Summers SPIE Proceedings, Volume 9035, Lung, Chest, and Abdomen II, doi:10.1117/12.2043837 (2014)
VTET: a variable threshold exact test for identifying disease-associated copy number variations enriched in short genomic regions Jianxin Shi, Xiaohong R. Yang, Neil E. Caporaso, Maria T. Landi, and Peng Li Frontiers in Genetics, doi://10.3389/fgene.2014.00053 (2014)
Accuracy Evaluation of the Unified P-Value from Combining Correlated P-Values Gelio Alves and Yi-Kuo Yu PLoS One, doi: 10.1371/journal.pone.0091225 (2014)
Differential Coding of Conspecific Vocalizations in the Ventral Auditory Cortical Stream Makoto Fukushima, Richard C. Saunders, David A. Leopold, Mortimer Mishkin, and Bruno B. Averbeck J. Neuroscience, doi: 10.1523/JNEUROSCI.3969-13.2014 (2014)
Contradictions in X-ray structures of intermediates in the photocycle of photoactive yellow protein Ville R. I. Kaila, Friedrich Schotte, Hyun Sun Cho, Gerhard Hummer & Philip A. Anfinrud Nature Chemistry, doi:10.1038/nchem.1898 (2014)
Practice and sleep form different aspects of skill Sunbin Song & Leonardo G. Cohen Nature Communications, doi:10.1038/ncomms4407 (2014)

Temperature-dependent solvation modulates the dimensions of disordered proteins René Wuttke, Hagen Hofmann, Daniel Nettels, Madeleine B. Borgia, Jeetain Mittal, Robert B. Best, and Benjamin Schuler PNAS, doi: 10.1073/pnas.1313006111 (2014)
Hypoosmotic Expression of Dunaliella bardawil ζ-Carotene Desaturase Is Attributed to a Hypoosmolarity-Responsive Element Different from Other Key Carotenogenic Genes Yong-Min Lao, Lan Xiao, Li-Xin Luo and Jian-Guo Jiang Plant Physiology, doi://10.1104/pp.114.235390 (2014)
Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue Jianxin Shi, Crystal N. Marconett, Jubao Duan et al. Nature Communications, doi:10.1038/ncomms4365 (2014)
Disordered amyloidogenic peptides may insert into the membrane and assemble into common cyclic structural motifs Hyunbum Jang, Fernando Teran Arce, Srinivasan Ramachandran, Bruce L. Kagan, Ratnesh Lal and Ruth Nussinov Chem. Soc. Rev., doi://10.1039/C3CS60459D (2014)
Abnormal cortical growth in schizophrenia targets normative modules of synchronized development Aaron F. Alexander-Bloch, Philip T. Reiss, Judith Rapoport, Harry McAdams, Jay N. Giedd, Ed T. Bullmore, Nitin Gogtay Biological Psychiatry, doi://10.1016/j.biopsych.2014.02.010 (2014)
Calcium Inhibition of Ribonuclease H1 Two-Metal Ion Catalysis Edina Rosta, Wei Yang, and Gerhard Hummer JACS, DOI: 10.1021/ja411408x (2014)

Multiscale free energy simulations: An efficient method for connecting classical MD simulations to QM or QM/MM free energies using Non-Boltzmann Bennett reweighting schemes Gerhard König, Phillip Stephen Hudson, Stefan Boresch, and H. Lee Woodcock J. Chem. Theory & Computation, DOI: 10.1021/ct401118k (2014)
A Network Characteristic That Correlates Environmental and Genetic Robustness Zeina Shreif, Vipul Periwal PLoS Computational Biology, DOI: 10.1371/journal.pcbi.1003474 (2014)
A GCH1 haplotype confers sex-specific susceptibility to pain crises and altered endothelial function in adults with sickle cell anemia Inna Belfer, Victoria Youngblood et al. Am. J. Hematology, DOI: 10.1002/ajh.23613 (2014)
Meta-analysis of Loci Associated with Age at Natural Menopause in African-American Women CTL Chen, C-T Liu, GK Chen, et al Human Molecular Genetics, doi: 10.1093/hmg/ddu041 (2014)
Predicting hydration free energies with a hybrid QM/MM approach: an evaluation of implicit and explicit solvation models in SAMPL4 Gerhard König, Frank C. Pickard IV, Ye Mei, Bernard R. Brooks J. Computer-Aided Molecular Design, doi://10.1007/s10822-014-9708-4 (2014)
Predicting Stroke Through Genetic Risk Functions CA Ibrahim-Verbaas,M Fornage, JC Bis, et al Stroke, doi: 10.1161/STROKEAHA.113.003044 (2014)

Multilocus Genetic Risk Score Associates With Ischemic Stroke in Case-Control and Prospective Cohort Studies R Malik, S Bevan, M Nalls et al Stroke, doi: 10.1161/STROKEAHA.113.002938 (2014)
Reverse regression: A method for joint analysis of multiple endpoints in randomized clinical trials Zhiwei Zhang Statistica Sinica, doi://10.5705/ss.2010.111 (2014)
Using single cell sequencing data to model the evolutionary history of a tumor Kyung In Kim and Richard Simon BMC Bioinformatics :27, doi: 10.1186/1471-2105-15-27 (2014)
Comprehensive Genomic Analysis of Rhabdomyosarcoma Reveals a Landscape of Alterations Affecting a Common Genetic Axis in Fusion-Positive and Fusion-Negative Tumors Jack F. Shern, Li Chen, Juliann Chmielecki, et al. Cancer Discovery, doi:10.1158/2159-8290.CD-13-0639 (2014)
Fluorescence excitation and ultraviolet absorption spectra and theoretical calculations for benzocyclobutane: Vibrations and structure of its excited S1(π,π*) electronic state Hee Won Shin, Esther J. Ocola, Sunghwan Kim and Jaan Laane J. Chem. Phys., doi://10.1063/1.4858412 (2014)
Spectral Tuning of Rhodopsin and Visual Cone Pigments Xiuwen Zhou , Dage Sundholm , Tomasz Adam Wesolowski , and Ville R. I. Kaila J.Am.Chem.Soc., DOI: 10.1021/ja411864m (2014)

RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder N Akula, J Barb, X Jiang, J R Wendland, K H Choi, S K Sen, L Hou, D T W Chen, G Laje, K Johnson, B K Lipska, J E Kleinman, H Corrada-Bravo, S Detera-Wadleigh, P J Munson and F J McMahon Molecular Psychiatry, doi: 10.1038/mp.2013.170 (2014)

2013 (180 papers)

Residue-level prediction of HIV-1 antibody epitopes based on neutralization of diverse viral strains Chuang, GY; Acharya, P; Schmidt, SD et al. J. Virol., DOI://10.1128/JVI.00984-13 (2013)
Integrated strategy for improving functional connectivity mapping using multiecho fMRI Kundu, P; Brenowitz, ND; Voon, V et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1301725110 (2013)
Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia Wang, E; Kawaoka, S; Yu, M et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1301045110 (2013)
Correlated biomarker measurement error: an important threat to inference in environmental epidemiology Pollack, AZ; Perkins, NJ; Mumford, SL; Ye, A; Schisterman, EF; Am. J. Epidemiol., DOI://10.1093/aje/kws209 (2013)
Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies Zhou, T; Zhu, J; Wu, X et al. Immunity, DOI://10.1016/j.immuni.2013.04.012 (2013)
Effective Preprocessing Procedures Virtually Eliminate Distance-Dependent Motion Artifacts in Resting State FMRI Jo, HJ; Gotts, SJ; Reynolds, RC et al. J Appl Math, DOI://10.1155/2013/935154 (2013)
A structural and molecular dynamics approach to understanding the peptide-receptive transition state of MHC-I molecules Mage, MG; Dolan, MA; Wang, R et al. Mol. Immunol., DOI://10.1016/j.molimm.2012.10.021 (2013)
The origin of B cell recurrent chromosomal translocations: proximity versus DNA damage Casellas, R; Resch, W; Hakim, O; Nussenzweig, MC; Mol. Cell, DOI://10.1016/j.molcel.2013.07.020 (2013)
PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum Jiang, L; Mu, J; Zhang, Q et al. Nature, DOI://10.1038/nature12361 (2013)
Subconjunctival Palomid 529 in the treatment of neovascular age-related macular degeneration Dalal, M; Jacobs-El, N; Nicholson, B et al. Graefes Arch. Clin. Exp. Ophthalmol., DOI://10.1007/s00417-013-2375-7 (2013)
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment Rietveld, CA; Medland, SE; Derringer, J et al. Science, DOI://10.1126/science.1235488 (2013)
Multivariate normally distributed biomarkers subject to limits of detection and receiver operating characteristic curve inference Perkins, NJ; Schisterman, EF; Vexler, A; Acad Radiol, DOI://10.1016/j.acra.2013.04.001 (2013)
Genome-wide association study of retinopathy in individuals without diabetes Jensen, RA; Sim, X; Li, X et al. PLoS ONE, DOI://10.1371/journal.pone.0054232 (2013)
Topographic diversity of fungal and bacterial communities in human skin Findley, K; Oh, J; Yang, J et al. Nature, DOI://10.1038/nature12171 (2013)
Accuracy loss due to selection bias in cohort studies with left truncation Schisterman, EF; Cole, SR; Ye, A; Platt, RW; Paediatr Perinat Epidemiol, DOI://10.1111/ppe.12073 (2013)
Age-dependent regulation of synaptic connections by dopamine D2 receptors Jia, JM; Zhao, J; Hu, Z; Lindberg, D; Li, Z; Nat. Neurosci., DOI://10.1038/nn.3542 (2013)
Instant super-resolution imaging in live cells and embryos via analog image processing York, AG; Chandris, P; Nogare, DD et al. Nat. Methods, DOI://10.1038/nmeth.2687 (2013)
Obstetric complications among US women with asthma Mendola, P; Laughon, SK; Männistö, TI et al. Am. J. Obstet. Gynecol., DOI://10.1016/j.ajog.2012.11.007 (2013)
Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error Stambolian, D; Wojciechowski, R; Oexle, K et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddt116 (2013)
A systems biology framework identifies molecular underpinnings of coronary heart disease Huan, T; Zhang, B; Wang, Z et al. Arterioscler. Thromb. Vasc. Biol., DOI://10.1161/ATVBAHA.112.300112 (2013)
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia Verhoeven, VJ; Hysi, PG; Wojciechowski, R et al. Nat. Genet., DOI://10.1038/ng.2554 (2013)
The altered landscape of the human skin microbiome in patients with primary immunodeficiencies Oh, J; Freeman, AF; , et al. Genome Res., DOI://10.1101/gr.159467.113 (2013)
Identification of an ABCB1 (P-glycoprotein)-positive carfilzomib-resistant myeloma subpopulation by the pluripotent stem cell fluorescent dye CDy1 Hawley, TS; Riz, I; Yang, W et al. Am. J. Hematol., DOI://10.1002/ajh.23387 (2013)

Mutations in DNA-binding loop of NFAT5 transcription factor produce unique outcomes on protein-DNA binding and dynamics Li, M; Shoemaker, BA; Thangudu, RR; Ferraris, JD; Burg, MB; Panchenko, AR; J Phys Chem B, DOI://10.1021/jp403310a (2013)
Severe painful vaso-occlusive crises and mortality in a contemporary adult sickle cell anemia cohort study Darbari, DS; Wang, Z; Kwak, M et al. PLoS ONE, DOI://10.1371/journal.pone.0079923 (2013)
Association of adiposity genetic variants with menarche timing in 92,105 women of European descent Fernández-Rhodes, L; Demerath, EW; Cousminer, DL et al. Am. J. Epidemiol., DOI://10.1093/aje/kws473 (2013)
TGF-ß regulates enamel mineralization and maturation through KLK4 expression Cho, A; Haruyama, N; Hall, B et al. PLoS ONE, DOI://10.1371/journal.pone.0082267 (2013)
Race, genetic ancestry and response to antidepressant treatment for major depression Murphy, E; Hou, L; Maher, BS et al. Neuropsychopharmacology, DOI://10.1038/npp.2013.166 (2013)
Genomic insights into the fate of colistin resistance and Acinetobacter baumannii during patient treatment Snitkin, ES; Zelazny, AM; Gupta, J et al. Genome Res., DOI://10.1101/gr.154328.112 (2013)

53BP1 alters the landscape of DNA rearrangements and suppresses AID-induced B cell lymphoma Jankovic, M; Feldhahn, N; Oliveira, TY et al. Mol. Cell, DOI://10.1016/j.molcel.2012.11.029 (2013)
Building a fission machine--structural insights into dynamin assembly and activation Chappie, JS; Dyda, F; J. Cell. Sci., DOI://10.1242/jcs.108845 (2013)
Global 'bootprinting' reveals the elastic architecture of the yeast TFIIIB-TFIIIC transcription complex in vivo Nagarajavel, V; Iben, JR; Howard, BH; Maraia, RJ; Clark, DJ; Nucleic Acids Res., DOI://10.1093/nar/gkt611 (2013)
Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation Wood, AR; Perry, JR; Tanaka, T et al. PLoS ONE, DOI://10.1371/journal.pone.0064343 (2013)
Human papillomavirus type 58 genome variations and RNA expression in cervical lesions Li, Y; Wang, X; Ni, T et al. J. Virol., DOI://10.1128/JVI.01154-13 (2013)
De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts Zhu, J; Wu, X; Zhang, B et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1306262110 (2013)

The role of macrophage class a scavenger receptors in a laser-induced murine choroidal neovascularization model Jawad, S; Liu, B; Li, Z et al. Invest. Ophthalmol. Vis. Sci., DOI://10.1167/iovs.12-11380 (2013)
Suppression of genetic recombination in the pseudoautosomal region and at subtelomeres in mice with a hypomorphic Spo11 allele Smagulova, F; Brick, K; Pu, Y; Sengupta, U; Camerini-Otero, RD; Petukhova, GV; BMC Genomics, DOI://10.1186/1471-2164-14-493 (2013)
Regional replication of association with refractive error on 15q14 and 15q25 in the Age-Related Eye Disease Study cohort Simpson, CL; Wojciechowski, R; Yee, SS; Soni, P; Bailey-Wilson, JE; Stambolian, D; Mol. Vis., 1090-0535 (2013)
The Papillomavirus Episteme: a central resource for papillomavirus sequence data and analysis Van Doorslaer, K; Tan, Q; Xirasagar, S et al. Nucleic Acids Res., DOI://10.1093/nar/gks984 (2013)
NGSPE: A pipeline for end-to-end analysis of DNA sequencing data and comparison between different platforms Huang, K; Yellapantula, V; Baier, L; Dinu, V; Comput. Biol. Med., DOI://10.1016/j.compbiomed.2013.05.025 (2013)
Genetic associations with valvular calcification and aortic stenosis Thanassoulis, G; Campbell, CY; Owens, DS et al. N. Engl. J. Med., DOI://10.1056/NEJMoa1109034 (2013)

Transforming growth factor-β3 (TGF-β3) knock-in ameliorates inflammation due to TGF-β1 deficiency while promoting glucose tolerance Hall, BE; Wankhade, UD; Konkel, JE et al. J. Biol. Chem., DOI://10.1074/jbc.M113.480764 (2013)
Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants Parker, SC; Stitzel, ML; Taylor, DL et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1317023110 (2013)
Using exome sequencing to reveal mutations in TREM2 presenting as a frontotemporal dementia-like syndrome without bone involvement Guerreiro, RJ; Lohmann, E; Brás, JM et al. JAMA Neurol, DOI://10.1001/jamaneurol.2013.579 (2013)
Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion Huyghe, JR; Jackson, AU; Fogarty, MP et al. Nat. Genet., DOI://10.1038/ng.2507 (2013)
PhosSA: Fast and accurate phosphorylation site assignment algorithm for mass spectrometry data Fahad Saeed, Trairak Pisitkun, Jason D Hoffert, Sara Rashidian, Guanghui Wang, Marjan Gucek and Mark A Knepper Proteome Sci. , doi: 10.1186/1477-5956-11-S1-S14 (2013)
Molecular insights into the reversible formation of tau protein fibrils Yin Luo, Paul Dinkel, Xiang Yu, Martin Margittai, Jie Zheng, Ruth Nussinov, Guanghong Wei and Buyong Ma Chem. Commun., DOI: 10.1039/C3CC00241A (2013)

Interactome Maps of Mouse Gene Regulatory Domains Reveal Basic Principles of Transcriptional Regulation Kyong-Rim Kieffer-Kwon, Zhonghui Tang, Ewy Mathe et al. Cell, doi://10.1016/j.cell.2013.11.039 (2013)
Design of RNA splicing analysis null models for post hoc filtering of Drosophila head RNA-Seq data with the splicing analysis kit (Spanki) David Sturgill, John H Malone, Xia Sun, Harold E Smith, Leonard Rabinow, Marie-Laure Samson and Brian Oliver BMC Bioinformatics, doi:10.1186/1471-2105-14-320 (2013)
Theta band activity in response to emotional expressions and its relationship with gamma band activity as revealed by MEG and advanced beamformer source imaging Qian Luo, Xi Cheng, Tom Holroyd, Duo Xu, Frederick W. Carver and James Blair Frontiers in Human Neuroscience, doi: 10.3389/fnhum.2013.00940 (2013)
Overfitting, generalization, and MSE in class probability estimation with high-dimensional data Kyung In Kim, Richard Simon Biometric Journal, DOI: 10.1002/bimj.201300083 (2013)
Radionuclide labeling and evaluation of candidate radioligands for PET imaging of histone deacetylase in the brain Young Jun Seo, Lisa Muench, Alicia Reid, Jinzhu Chen, Yeona Kang, Jacob M. Hooker, Nora D. Volkow, Joanna S. Fowler, Sung Won Kim Bioorganic and Medicinal Chemistry Letters 23:6700-6705 (2013)
An integrated systems genetics screen reveals the transcriptional structure of inherited predisposition to metastatic disease Farhoud Faraji, Ying Hu, Gang Wu, Natalie E. Goldberger, Renard C. Walker, Jinghui Zhang and Kent W. Hunter Genome Research, doi: 10.1101/gr.166223.113 (2013)
Efficacy of Cyclin Dependent Kinase 4 Inhibitors as Potent Neuroprotective Agents against Insults Relevant to Alzheimer's Disease Priyankar Sanphui, Sumit Kumar Pramanik, Nandini Chatterjee, Ponnusamy Moorthi, Biswadip Banerji, Subhas Chandra Biswas PLoS One, doi: 10.1371/journal.pone.0078842 (2013)
Multiple Transport-Active Binding Sites Are Available for a Single Substrate on Human P-Glycoprotein (ABCB1) Eduardo E. Chufan, Khyati Kapoor, Hong-May Sim, Satyakam Singh, Tanaji T. Talele, Stewart R. Durell, Suresh V. Ambudkar PLoS One, DOI: 10.1371/journal.pone.0082463 (2013)
Prediction of the location and size of the stomach using patient characteristics for retrospective radiation dose estimation following radiotherapy Stephanie Lamart, Rebecca Imran, Steven L Simon, Kazutaka Doi, Lindsay M Morton, Rochelle E Curtis, Choonik Lee, Vladimir Drozdovitch, Roberto Maass-Moreno, Clara C Chen, Millie Whatley, Donald L Miller, Karel Pacak and Choonsik Lee Physics in Medicine and Biology, doi:10.1088/0031-9155/58/24/8739 (2013)
Optimization of virus detection in cells using massively parallel sequencing Shasta D. McClenahan, Christine Uhlenhaut, Philip R. Krause Biologicals, DOI://10.1016/j.biologicals.2013.11.002 (2013)
Whole exome sequencing identifies variation in CYB5A and RNF10 associated with adiposity and type 2 diabetes. Huang K, Nair AK, Muller YL, Piaggi P, Bian L, Del Rosario M, Knowler WC, Kobes S, Hanson RL, Bogardus C, Baier LJ. Obesity, doi: 10.1002/oby.20647 (2013)
Antimicrobial activity of eugenol and cinnamaldehyde against extended spectrum beta lactamase producing enterobacteriaceae by in vitro and molecular docking analysis Lena Dhara, Anusri Tripathi Eur.J.Integrative Med., 10.1016/j.eujim.2013.08.005 (2013)

Efficient logistic regression designs under an imperfect population identifier Paul S. Albert, Aiyi Liu, Tonja Nansel Biometrics, DOI: 10.1111/biom.12106 (2013)
Molecular Isotopic Distribution Analysis (MIDAs) with Adjustable Mass Accuracy Gelio Alves, Aleksey Y. Ogurtsov, Yi-Kuo Yu J. Am. Soc. for Mass Spectrometry, doi://10.1007/s13361-013-0733-7 (2013)
Vitamin D-Binding Protein and Vitamin D Status of Black Americans and White Americans Camille E. Powe, , Michele K. Evans, Julia Wenger, Alan B. Zonderman, Anders H. Berg, Michael Nalls, Hector Tamez, Dongsheng Zhang, Ishir Bhan, S. Ananth Karumanchi, Neil R. Powe, and Ravi Thadhani New England J. Medicine, DOI: 10.1056/NEJMoa1306357 (2013)
PW02-001 - Exome sequencing for autoinflammatory disorders SE Boyden, Q Zhou, I Aksentijevich and DL Kastner Pediatric Rheumatology, doi:10.1186/1546-0096-11-S1-A141 (2013)
Endogenous Carbamylation of Renal Medullary Proteins J'Neka S. Claxton, Pablo C. Sandoval, Gary Liu, Chung-Lin Chou, Jason D. Hoffert, and Mark A. Knepper PLoS One, doi: 10.1371/journal.pone.0082655 (2013)
Interpreting the effects of altered brain anatomical connectivity on fMRI functional connectivity: a role for computational neural modeling Barry Horwitz, Chuhern Hwang, and Jeff Alstott Frontiers in Human Neuroscience, doi: 10.3389/fnhum.2013.00649 (2013)

Shared Genetic Susceptibility to Ischemic Stroke and Coronary Artery Disease Dichgans, Malik et al. Stroke, doi: 10.1161/STROKEAHA.113.002707 (2013)
Mtr4-like Protein Coordinates Nuclear RNA Processing for Heterochromatin Assembly and for Telomere Maintenance Nathan N. Lee, Venkata R. Chalamcharla, Francisca Reyes-Turcu, Sameet Mehta, Martin Zofall, Vanivilasini Balachandran, Jothy Dhakshnamoorthy, Nitika Taneja, Soichiro Yamanaka, 5, Ming Zhou, Shiv I.S. Grewal Cell, doi://10.1016/j.cell.2013.10.027 (2013)
Testing multiple biological mediators simultaneously Simina M. Boca, Rashmi Sinha, Amanda J. Cross, Steven C. Moore and Joshua N. Sampson Bioinformatics, doi: 10.1093/bioinformatics/btt633 (2013)
Variational Optimization of an All-Atom Implicit Solvent Force Field To Match Explicit Solvent Simulation Data Sandro Bottaro, Kresten Lindorff-Larsen, and Robert B. Best J. Chem. Theory and Computation, DOI: 10.1021/ct400730n (2013)
Mechanism of Membrane Permeation Induced by Synthetic β-Hairpin Peptides Kshitij Gupta, Hyunbum Jang, Kevin Harlen, Anu Puri, Ruth Nussinov, Joel P. Schneider, Robert Blumenthal Biophys. J. , doi: 10.1016/j.bpj.2013.09.040 (2013)
Ebola Virus RNA Editing Depends on the Primary Editing Site Sequence and an Upstream Secondary Structure Masfique Mehedi, Thomas Hoenen, Shelly Robertson, Stacy Ricklefs, Michael A. Dolan, Travis Taylor, Darryl Falzarano, Hideki Ebihara, Stephen F. Porcella, Heinz Feldmann PLoS Pathogens, doi:10.1371/journal.ppat.1003677 (2013)

Massively Parallel Sequencing Reveals an Accumulation of De Novo Mutations and an Activating Mutation of LPAR1 in a Patient with Metastatic Neuroblastoma JS Wei, P Johansson, L Chen et al PLoS One, doi:10.1371/journal.pone.0077731 (2013)
Mitochondrial DNA sequence associations with dementia and amyloid-β in elderly African Americans GJ Tranah, JS Yokoyoma, SM Katzman et al. Neurobiology of Aging, doi:/10.1016/j.neurobiolaging.2013.05.02 (2013)
Functional Linear Models for Association Analysis of Quantitative Traits Ruzong Fan, Yifan Wang, James L. Mills, Alexander F. Wilson, Joan E. Bailey-Wilson, Momiao Xiong Genetic Epidemiology, DOI: 10.1002/gepi.21757 (2013)
Singular Value Decomposition of the Radial Distribution Function for Hard Sphere and Square Well Potentials Travis Hoppe PLoS One, doi:10.1371/journal.pone.0075792 (2013)
Brain Docosahexaenoic Acid [DHA] Incorporation and Blood Flow Are Increased in Chronic Alcoholics: A Positron Emission Tomography Study Corrected for Cerebral Atrophy J.C. Umhau, W. Zhou, S. Thada et al PLoS One, doi:10.1371/journal.pone.0075333 (2013)
Cyclic N-Terminal Loop of Amylin Forms Non Amyloid Fibers Stephanie M. Cope, Sandip Shinde, Robert B. Best, Giovanna Ghirlanda, Sara M. Vaiana Biophys. J. , doi: 10.1016/j.bpj.2013.08.026 (2013)

Infrared, Raman, and Ultraviolet Absorption Spectra and Theoretical Calculations and Structure of 2, 6-Difluoropyridine in its Ground and Excited Electronic States Hong-Li Sheu, Sunghwan Kim, and Jaan Laane J. Phys. Chem. A, DOI://10.1021/jp407592r (2013)
Assessment of Parkinson's disease risk loci in Greece E. Kara, G. Xiromerisiou, C. Spanaki et al Neurobiology of Aging, doi://10.1016/j.neurobiolaging.2013.07.011 (2013)
Sequential Monte Carlo Tracking for Marginal Artery Segmentation on CT Angiography by Multiple Cue Fusion Shijun Wang, Brandon Peplinski, Le Lu, Weidong Zhang, Jianfei Liu, Zhuoshi Wei, Ronald M. Summers Medical Image Computing and Computer-Assisted Intervention 8150:518-525 (2013)
Strategies for developing prediction models from genome-wide association studies. Jincao Wu, Ruth M. Pfeiffer andMitchell H. Gail Genet Epidemiol. , doi: 10.1002/gepi.21762 (2013)
Phosphate release coupled to rotary motion of F1-ATPase Kei-ichi Okazaki and Gerhard Hummer PNAS, doi: 10.1073/pnas.1305497110 (2013)
Genome-wide analysis of blood pressure variability and ischemic stroke Yadav, S; Cotlarciuc, I; Munroe, PB et al. Stroke, DOI://10.1161/STROKEAHA.113.002186 (2013)

Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation Gangqing Hu, Qingsong Tang, Suveena Sharma, Fang Yu, Thelma M Escobar, Stefan A Muljo, Jinfang Zhu & Keji Zhao Nature Immunology, doi:10.1038/ni.2712 (2013)
Specific and Non-Specific Protein Association in Solution: Computation of Solvent Effects and Prediction of First-Encounter Modes for Efficient Configurational Bias Monte Carlo Simulations Antonio Cardone , Harish C. Pant , and Sergio A Hassan J. Phys. Chem. B, DOI: 10.1021/jp4050594 (2013)
Molecular Structure of β-Amyloid Fibrils in Alzheimer's Disease Brain Tissue Jun-Xia Lu, Wei Qiang, Wai-Ming Yau, Charles D. Schwieters, Stephen C. Meredith, Robert Tycko Cell, doi: 10.1016/j.cell.2013.08.035 (2013)
A fast multilocus test with adaptive SNP selection for large-scale genetic-association studies Han Zhang, Jianxin Shi, Faming Liang, William Wheeler, Rachael Stolzenberg-Solomon and Kai Yu Eur. J. Human Genetics, doi: 10.1038/ejhg.2013.201 (2013)
Sequence selectivity of the cleavage sites induced by topoisomerase I inhibitors: a molecular dynamics study Fung-Ming Siu and Yves Pommier Nucleic Acids Research, doi://10.1093/nar/gkt791 (2013)
Gene Synthesis Method Based on Overlap Extension PCR and DNAWorks Program Gang Li, Bing-Xue Dong, Yu-Huan Liu, Chang-Jie Li, Li-Ping Zhang Synthetic Biology - Methods in Molecular Biology 1073:9-17 (2013)
Effect of acute acid-base disturbances on ErbB1/2 tyrosine phosphorylation in rabbit renal proximal tubules Lara A. Skelton, Walter F. Boron Am. J. Physiol. - Renal Physiol., DOI: 10.1152/ajprenal.00307.2013 (2013)
Genetic comorbidities in Parkinson's disease MA Nalls,M Saad et al. Human Molecular Genetics, doi: 10.1093/hmg/ddt465 (2013)
Familial Alzheimer's Disease Osaka Mutant (ΔE22) β-Barrels Suggest an Explanation for the Different Aβ1-40/42 Preferred Conformational States Observed by Experiment Hyunbum Jang , Fernando Teran Arce , Srinivasan Ramachandran , Bruce L. Kagan , Ratnesh Lal , and Ruth Nussinov J. Phys. Chem. B, DOI: 10.1021/jp405389n (2013)
Life and death of a cardiac calcium spark Michael D. Stern, Eduardo Ríos, and Victor A. Maltsev J. Gen. Physiol. , doi: 10.1085/jgp.201311034 (2013)
Conformational Analysis of NMDA Receptor GluN1, GluN2, and GluN3 Ligand-Binding Domains Reveals Subtype-Specific Characteristics Yongneng Yao, John Belcher, Anthony J. Berger, Mark L. Mayer, Albert Y. Lau Structure, doi: 10.1016/j.str.2013.07.011 (2013)
Correlated vibrations in ion-pair dynamics in mechanoactivation identify functional domains of force-dependent titin kinase Ming-Chya Wu, Jeffrey G. Forbes and Kuan Wang Soft Matter, DOI: 10.1039/C3SM51539G (2013)

Genome-Wide Association of Body Fat Distribution in African Ancestry Populations Suggests New Loci Ching-Ti Liu, Keri L. Monda, Kira C. Taylor et al PLoS Genetics, doi:10.1371/journal.pgen.1003681 (2013)
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition Alika K Maunakea, Iouri Chepelev, Kairong Cui and Keji Zhao Cell Research, doi: 10.1038/cr.2013.110 (2013)
RCircos: an R package for Circos 2D track plots Hongen Zhang, Paul Meltzer, Sean Davis BMC Bioinformatics, doi:10.1186/1471-2105-14-244 (2013)
Top3 β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation Xu D, Shen W, Guo R, Xue Y, Peng W, Sima J, Yang J, Sharov A, Srikantan S, Yang J, Fox D 3rd, Qian Y, Martindale JL, Piao Y, Machamer J, Joshi SR, Mohanty S, Shaw AC, Lloyd TE, Brown GW, Ko MS, Gorospe M, Zou S, Wang W. Nature Neuroscience, doi: 10.1038/nn.3479 (2013)
Computational detection of abundant long-range nucleotide covariation in Drosophila genomes Eckart Bindewald and Bruce A Shapiro RNA, doi: 10.1261/rna.037630.112 (2013)
Genome-wide meta-analysis identifies new susceptibility loci for migraine Anttila, V; Winsvold, BS; Gormley, P et al. Nat. Genet., DOI://10.1038/ng.2676 (2013)

Multi-SNP Analysis of GWAS Data Identifies Pathways Associated with Nonalcoholic Fatty Liver Disease Qing-Rong Chen, Rosemary Braun, Ying Hu, Chunhua Yan, Elizabeth M. Brunt, Daoud Meerzaman, Arun J. Sanyal, Kenneth Buetow PLoS One, doi:10.1371/journal.pone.0065982 (2013)
Genomic Analysis of Stress Response against Arsenic in Caenorhabditis elegans Surasri N. Sahu, Jada Lewis, Isha Patel, Serdar Bozdag, Jeong H. Lee, Robert Sprando, and Hediye Nese Cinar PLoS One, doi://10.1371/journal.pone.0066431 (2013)
Reduced thalamic volumes in major depressive disorder AC Nugent, RM Davis, CA Zarate Jr, WC Drevets Psych. Res. Neuroimaging, doi://10.1016/j.pscychresns.2013.05.004 (2013)
Graph theoretical analysis of resting magnetoencephalographic functional connectivity networks Lindsay Rutter, Sreenivasan R. Nadar, Tom Holroyd, Frederick W. Carver, Jose Apud, Daniel R. Weinberger and Richard Coppola Frontiers in Computational Neuroscience, doi://10.3389/fncom.2013.00093 (2013)
Evaluation of the Use of Surrogate Tissues for Calculating Radiation Dose to Lymphatic Nodes from External Photon Beams Stephanie Lamart, Brian E. Moroz and Choonsik Lee Radiation Protection Dosimetry, doi: 10.1152/ajprenal.00210.2013 (2013)
Visual Phrase Learning and Its Application in Computed Tomographic Colonography Shijun Wang, Matthew McKenna, Zhuoshi Wei, Jiamin Liu, Peter Liu, Ronald M. Summers Medical Image Computing and Computer-Assisted Intervention 8149:243 (2013)

Ordinal latent variable models and their application in the study of newly licensed teenage drivers John C Jackson, Paul S. Albert, Zhiwei Zhang and Bruce Simons-Morton Appl. Statist. , DOI: 10.1111/j.1467-9876.2012.01065.x (2013)
Striatal dopamine release and genetic variation of the serotonin 2C receptor in humans Brian J Mickey, Benjamin J Sanford, Tiffany M Love, Pei-Hong Shen, Colin Hodgkinson, Christian S Stohler, David Goldman, Jon-Kar Zubieta J Neurosci., doi: 10.1523/JNEUROSCI.1260-12.2012 (2013)
DRD2/ANKK1 Taq1A polymorphism (rs1800497) has opposing effects on D2/3 receptor binding in healthy controls and patients with major depressive disorder Savitz J, Hodgkinson CA, Martin-Soelch C, Shen PH, Szczepanik J, Nugent AC, Herscovitch P, Grace AA, Goldman D, Drevets WC Int J Neuropsychopharmacol., doi: 10.1017/S146114571300045X (2013)
Contribution of nucleosome binding preferences and co-occurring DNA sequences to transcription factor binding X He, R Chatterjee, S John, H Bravo, Bk Sathyanarayana, SC Biddie, PC FitzGerald, JA Stamatoyannopoulos, GL Hager, C Vinson BMC Genomics, doi:10.1186/1471-2164-14-428 (2013)
Probing the transient dark state of substrate binding to GroEL by relaxation-based solution NMR David S. Libich, Nicolas L. Fawzia, Jinfa Ying, and G. Marius Clore PNAS, doi: 10.1073/pnas.1305715110 (2013)
HASP server: a database and structural visualization platform for comparative models of influenza A hemagglutinin proteins Xavier I Ambroggio, Jennifer Dommer, Vivek Gopalan, Eleca J Dunham, Jeffery K Taubenberger and Darrell E Hurt BMC Bioinformatics, doi:10.1186/1471-2105-14-197 (2013)

Host immune constraints on malaria transmission: insights from population biology of within-host parasites Philip G McQueen, Kim C Williamson and F Ellis McKenzie Malaria Journal, doi:10.1186/1475-2875-12-206 (2013)
VLDP web server: a powerful geometric tool for analysing protein structures in their environment Jérémy Esque, Sylvain Léonard, Alexandre G. de Brevern and Christophe Oguey Nucleic Acids Research, doi: 10.1093/nar/gkt509 (2013)
mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex. Dillman AA, Hauser DN, Gibbs JR, Nalls MA, McCoy MK, Rudenko IN, Galter D, Cookson MR. Nature Neuroscience, doi: 10.1038/nn.3332 (2013)
Proteome-Wide Measurement of Protein Half-Lives and Translation Rates in Vasopressin-Sensitive Collecting Duct Cells Pablo C. Sandoval, Dane H. Slentz, Trairak Pisitkun, Fahad Saeed, Jason D. Hoffert and Mark A. Knepper J. Am. Soc. Nephrologu, doi: 10.1681/ASN.2013030279 (2013)
Anatomical coupling among distributed cortical regions in youth varies as a function of individual differences in vocabulary abilities Nancy Raitano Lee, Armin Raznahan, Gregory L. Wallace, Aaron Alexander-Bloch, Liv S. Clasen, Jason P. Lerch, Jay N. Giedd Human Brain Mapping, DOI://10.1002/hbm.22299 (2013)
Serum Iron Levels and the Risk of Parkinson Disease: A Mendelian Randomization Study I Pichler, F Del Greco et al. PLoS Medicine, doi:10.1371/journal.pmed.1001462 (2013)

HIV-1 Envelope Glycoprotein Trimers Display Open Quaternary Conformation When Bound to the gp41 Membrane-Proximal External-Region-Directed Broadly Neutralizing Antibody Z13e1 Audray K. Harris, Alberto Bartesaghi, Jacqueline L. S. Milne and Sriram Subramaniam J. Virology, doi:10.1128/JVI.03284-12 (2013)
DRD2 polymorphisms modulate reward and emotion processing, dopamine neurotransmission and openness to experience Peciña M, Mickey BJ, Love T, Wang H, Langenecker SA, Hodgkinson C, Shen PH, Villafuerte S, Hsu D, Weisenbach SL, Stohler CS, Goldman D, Zubieta JK Cortex, doi: 10.1016/j.cortex.2012.01.010 (2013)
Prefrontal white matter impairment in substance users depends upon the catechol-o-methyl transferase (COMT) val158met polymorphism Zhang X, Lee MR, Salmeron BJ, Stein DJ, Hong LE, Geng X, Ross TJ, Li N, Hodgkinson C, Shen PH, Yang Y, Goldman D, Stein EA. Neuroimage, doi: 10.1016/j.neuroimage.2012.11.056 (2013)
The functional DRD3 Ser9Gly polymorphism (rs6280) is pleiotropic, affecting reward as well as movement Savitz J, Hodgkinson CA, Martin-Soelch C, Shen PH, Szczepanik J, Nugent A, Herscovitch P, Grace AA, Goldman D, Drevets WC. PLoS One, doi: 10.1371/journal.pone.0054108 (2013)
Association of genetic variation in pharmacodynamic factors with methadone dose required for effective treatment of opioid addiction Levran O, Peles E, Randesi M, Shu X, Ott J, Shen PH, Adelson M, Kreek MJ. Pharmacogenomics, doi: 10.2217/pgs.13.58 (2013)
Atomic-resolution structural information from scattering experiments on macromolecules in solution Jürgen Köfinger & Gerhard Hummer Phys. Rev. E , DOI:10.1103/PhysRevE.87.052712 (2013)

Evolutionary Pressure on the Topology of Protein Interface Interaction Networks Margaret E Johnson & Gerhard Hummer J. Phys. Chem. B, DOI: 10.1021/jp402944e (2013)
Genome-wide localization of exosome components to active promoters and chromatin insulators in Drosophila Lim SJ, Boyle PJ, Chinen M, Dale RK, Lei EP Nucleic Acids Research, doi: 10.1093/nar/gkt037 (2013)
A compendium of RNA-binding motifs for decoding gene regulation Ray D1, Kazan H, Cook KB, et al. Nature, doi: 10.1038/nature12311 (2013)
Messenger RNA is a functional component of a chromatin insulator complex Matzat LH1, Dale RK, Lei EP EMBO Rep., DOI: 10.1038/embor.2013.118 (2013)
Global analysis of the effects of the V2 receptor antagonist satavaptan on protein phosphorylation in collecting duct. Hoffert JD, Pisitkun T, Saeed F, Wilson JL, Knepper MA Am J Physiol Renal Physiol., DOI: 10.1152/ajprenal.00497.2013 (2013)
CAMS-RS: Clustering Algorithm for Large-Scale Mass Spectrometry Data Using Restricted Search Space and Intelligent Random Sampling Saeed F, Hoffert JD, Knepper MA IEEE/ACM Trans Comput Biol Bioinform., doi://10.1109/TCBB.2013.152 (2013)

A Genome-wide Map of CTCF Multivalency Redefines the CTCF Code Hirotaka Nakahashi, Kyong-Rim Kieffer Kwon, Wolfgang Resch, Laura Vian, Marei Dose, Diana Stavreva, Ofir Hakim, Nathanael Pruett, Steevenson Nelson, Arito Yamane, Jason Qian, Wendy Dubois, Scott Welsh, Robert D. Phair, B. Franklin Pugh, Victor Lobanenkov, Gordon L. Hager, and Rafael Casellas Cell Reports, doi://10.1016/j.celrep.2013.04.024 (2013)
Global Regulation of Promoter Melting in Naive Lymphocytes Fedor Kouzine, Damian Wojtowicz, Arito Yamane, Wolfgang Resch, Kyong-Rim Kieffer-Kwon, Russell Bandle, Steevenson Nelson, Hirotaka Nakahashi, Parirokh Awasthi, Lionel Feigenbaum, Herve Menoni, Jan Hoeijmakers, Wim Vermeulen, Hui Ge, Teresa M. Przytycka, David Levens, and Rafael Casellas Cell , doi://10.1016/j.cell.2013.04.033 (2013)
Therapeutic Response in Feline Sandhoff Disease Despite Immunity to Intracranial Gene Therapy Bradbury AM, Cochran JN, McCurdy VJ, Johnson AK et al Mol. Ther. , doi: 10.1038/mt.2013.86 (2013)
A 5′-Flanking Region of Gonadotropin-Regulated Testicular RNA Helicase (GRTH/DDX25) Gene Directs Its Cell-Specific Androgen-Regulated Gene Expression in Testicular Germ Cells Raghuveer Kavarthapu, Chon-Hwa Tsai-Morris, Masato Fukushima, James Pickel and Maria L. Dufau Endocrinology, doi: 10.1210/en.2012-2230 (2013)
Improving Peptide Identification Sensitivity in Shotgun Proteomics by Stratification of Search Space Gelio Alves and Yi-Kuo Yu J. Proteome Research, DOI: 10.1021/pr301139y (2013)
A simplified representation of anisotropic charge distributions within proteins Travis Hoppe J. Chem. Phys., doi://10.1063/1.4803099 (2013)
Proteomic Profiling and Pathway Analysis of the Response of Rat Renal Proximal Convoluted Tubules to Metabolic Acidosis Kevin L. Schauer, Dana M Freund, Jessica E. Prenni, and Norman P. Curthoys Renal Physiology, doi: 10.1152/ajprenal.00210.2013 (2013)
Three-Dimensional Structure of CAP-Gly Domain of Mammalian Dynactin Determined by Magic Angle Spinning NMR Spectroscopy: Conformational Plasticity and Interactions with End Binding Protein EB1 S. Yan, G. Hou, CD Schwieters, S Ahmed, JC Williams T Polenova J. Mol. Biol. , doi://10.1016/j.jmb.2013.04.027 (2013)
CG methylated microarrays identify a novel methylated sequence bound by the CEBPB| ATF4 heterodimer that is active in vivo Ishminder K. Mann, Raghunath Chatterjee, Jianfei Zhao et al. Genome Research, doi:10.1101/gr.146654.112 (2013)
Pointwise confidence intervals for a survival distribution with small samples or heavy censoring Michael P. Fay, Erica H. Brittain and Michael A. Proschan Biostatistics, doi: 10.1093/biostatistics/kxt016 (2013)
Degenerate polymerase chain reaction strategy with DNA microarray for detection of multiple and various subtypes of virus during blood screening K. Takizawa, T. Nakashima, T Mizukami et al. Transfusion, DOI: 10.1111/trf.12193 (2013)
Genome-wide association study of age at menarche in African-American women EW Demerath, C-T Liu, N Franceschini et al. Human Molecular Genetics, doi: 10.1093/hmg/ddt181 (2013)

Reconciling Mediating and Slaving Roles of Water in Protein Conformational Dynamics Li Zhao, Wenzhao Li, and Pu Tian PLoS One, doi://10.1371/journal.pone.0060553 (2013)
Vasopressin and the regulation of aquaporin-2 Justin L. L. Wilson, Carlos A. Miranda, Mark A. Knepper Clinical and Experimental Nephrology, doi://10.1007/s10157-013-0789-5 (2013)
Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: Systematic review and meta-analysis of 14 015 stroke cases and pooled analysis of primary biomarker data from up to 60 883 individuals TA Khan, T Shah, D Prieto et al. Int. J. Epidemiol. , doi: 10.1093/ije/dyt034 (2013)
Controlling the local false discovery rate in the adaptive Lasso Joshua N Sampson & Nilanjan Chatterjee Biostatistics, doi: 10.1093/biostatistics/kxt008 (2013)
Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli GA Snyder, C Cirl, J Jiang et al PNAS, doi: 10.1073/pnas.1215770110 (2013)
A crossed random effects modeling approach for estimating diagnostic accuracy from ordinal ratings without a gold standard Yunlong Xie, Zhen Chen, Paul S. Albert Statistics in Medicine, DOI: 10.1002/sim.5784 (2013)

Pharmacophore and 3D-QSAR Characterization of 6-arylquinazolin-4-amines as Cdc2-like kinase 4 (Clk4) and Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A (Dyrk1A) Inhibitors Yongmei Pan , Yanli Wang, and Stephen H. Bryant J. Chem. Inf. Model. , DOI: 10.1021/ci300625c (2013)
Effects of pre-existing anti-carrier immunity and antigenic element multiplicity on efficacy of a modular virus-like particle vaccine Yap P. Chuan, Tania Rivera-Hernandez, Nani Wibowo, Natalie K. Connors, Yang Wu, Fiona K. Hughes, Linda H. L. Lua, Anton P. J. Middelberg Biotech. & Bioengg. , DOI: 10.1002/bit.24907 (2013)
Global Analysis of Neuronal Phosphoproteome Regulation by Chondroitin Sulfate Proteoglycans Panpan Yu, Trairak Pisitkun, Guanghui Wang, Rong Wang, Yasuhiro Katagiri, Marjan Gucek, Mark A. Knepper, Herbert M. Geller PLoS One, doi:10.1371/journal.pone.0059285 (2013)
The alkaline pectate lyase PEL168 of Bacillus subtilis heterologously expressed in Pichia pastoris is more stable and efficient for degumming ramie fiber Chengjie Zhang, Jia Yao,Cheng Zhou,Liangwei Mao, Guimin Zhang, Yanhe Ma BMC Biotechnology, doi:10.1186/1472-6750-13-26 (2013)
In Silico, In Vitro, and In Vivo Studies Indicate the Potential Use of Bolaamphiphiles for Therapeutic siRNAs Delivery Taejin Kim, Kirill A. Afonin, Mathias Viard, Alexey Y Koyfman, Selene Sparks, Eliahu Heldman, Sarina Grinberg, Charles Linder, Robert P Blumenthal and Bruce A Shapiro Mol. Therapy - Nuc. Acids, doi:10.1038/mtna.2013.5 (2013)
RNAi triggered by specialized machinery silences developmental genes and retrotransposons Soichiro Yamanaka, Sameet Mehta, Francisca E. Reyes-Turcu, Fanglei Zhuang, Ryan T. Fuchs, Yikang Rong, Gregory B. Robb & Shiv I. S. Grewal Nature, doi:10.1038/nature11716 (2013)

Transcription-dependent dynamic supercoiling is a short-range genomic force Fedor Kouzine, Ashutosh Gupta, Laura Baranello, Damian Wojtowicz, Khadija Ben-Aissa, Juhong Liu, Teresa M Przytycka & David Levens Nature Structural & Molecular Biology, doi:10.1038/nsmb.2517 (2013)
X-Ray crystallographic structural characteristics of Arabidopsis hemoglobin I and their functional implications Nitika Mukhi, Sonali Dhindwal, Sheetal Uppal, Pravindra Kumar, Jagreet Kaur, Suman Kundu Biochim. et Biophys. Acta, doi://10.1016/j.bbapap.2013.02.024 (2013)
Engineering strategy to improve peptide analogs: from structure-based computational design to tumor homing David Zanuy, Francisco J. Sayago, Guillem Revilla-López, Gema Ballano, Lilach Agemy, Venkata Ramana Kotamraju, Ana I. Jiménez, Carlos Cativiela, Ruth Nussinov, April M. Sawvel, Galen Stucky, Erkki Ruoslahti, Carlos Alemán J. Computer-Aided Mol. Design, doi:10.1007/s10822-012-9623-5 (2013)
A novel taurocyamine kinase found in the protist Phytophthora infestans Kouji Uda, Michihiro Hoshijima, Tomohiko Suzuki Comp. Biochem. Phys. Part B: Biochem & Mol. Bio. , doi://10.1016/j.cbpb.2013.03.003 (2013)
Structure and accessibility of HA trimers on intact 2009 H1N1 pandemic influenza virus to stem region-specific neutralizing antibodies AK Harris, JR Meyerson, Y Matsuoka, O Kuybeda, A Moran, D Bliss, SR Das, JW Yewdell, G Sapiro, K Subbarao, and S Subramaniam PNAS, doi: 10.1073/pnas.1214913110 (2013)
Gene Synthesis by Assembly of Deoxyuridine-Containing Oligonucleotides Romualdas Vaisvila, Jurate Bitinaite Methods in Molecular Biology, doi: 10.1007/978-1-62703-293-3_12 (2013)

The Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of Calcineurin Simina Grigoriu, Rachel Bond, Pilar Cossio, Jennifer A. Chen, Nina Ly, Gerhard Hummer, Rebecca Page, Martha S. Cyert, Wolfgang Peti PLoS Biology, doi:10.1371/journal.pbio.1001492 (2013)
Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network Z Chen, H Tang, R Qayyum, UM Schick, MA Nalls et al. Human Molecular Genetics, doi: 10.1093/hmg/ddt087 (2013)
Common Variants Within Oxidative Phosphorylation Genes Influence Risk of Ischemic Stroke and Intracerebral Hemorrhage CD Anderson, A Biffi, MA Nalls, et al. & the International Stroke Genetics Consortium Stroke, doi: 10.1161/STROKEAHA.112.672089 (2013)
Antedependence models for nonstationary categorical longitudinal data with ignorable missingness likelihood-based inference Yunlong Xie, Dale Zimmerman Statistics in Medicine, DOI: 10.1002/sim.5763 (2013)
Sequence dependence of C-end rule peptides in binding and activation of neuropilin-1 receptor David Zanuy, Rohith Kotla, Ruth Nussinov, Tambet Teesalu, Kazuki N. Sugahara, Carlos Alemán, Nurit Haspel J. Struct. Biol. , doi://10.1016/j.jsb.2013.02.006 (2013)
Electrostatic spectral tuning mechanism of the green fluorescent protein Ville R. I. Kaila , Robert Send and Dage Sundholm Phys. Chem. Chem. Phys., DOI: 10.1039/C3CP00058C (2013)

Alzheimer's disease: Which type of amyloid-preventing drug agents to employ? Hyunbum Jang , Laura Connelly , Fernando Teran Arce , Srinivasan Ramachandran , Ratnesh Lal , Bruce L Kagan and Ruth Nussinov Phys. Chem. Chem. Phys., DOI: 10.1039/C3CP00017F (2013)
Control of breathing by interacting pontine and pulmonary feedback loops Yaroslav I. Molkov, Bartholomew J. Bacak, Thomas E. Dick, and Ilya A. Rybak Frontiers in Neural Circuits, doi: 10.3389/fncir.2013.00016 (2013)
Protein charge and mass contribute to the spatio-temporal dynamics of protein-protein interactions in a minimal proteome Yu Xu, Hong Wang, Ruth Nussinov, Buyong Ma Proteomics, DOI: 10.1002/pmic.201100540 (2013)
Differential requirements for mRNA folding partially explain why highly expressed proteins evolve slowly C Park, X Chen, J-R Yang, J Zhang PNAS, doi: 10.1073/pnas.1218066110 (2013)
The Val158Met COMT polymorphism is a modifier of the age at onset in Parkinson's disease with a sexual dimorphism S Klebe, J-L Golmard, MA Nalls et al, French Parkinson's Disease Genetics Study Group and the International Parkinson's Disease Genomics Consortium J Neurol Neurosurg Psychiatry , doi:10.1136/jnnp-2012-304475 (2013)
The Convergence of Maturational Change and Structural Covariance in Human Cortical Networks Aaron Alexander-Bloch, Armin Raznahan, Ed Bullmore, and Jay Giedd J. Neuroscience , doi: 10.1523/JNEUROSCI.3554-12.2013 (2013)

Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer Li-Jun Di, Jung S. Byun, Madeline M. Wong, Clay Wakano, Tara Taylor, Sven Bilke, Songjoon Baek, Kent Hunter, Howard Yang, Maxwell Lee, Cecilia Zvosec, Galina Khramtsova, Fan Cheng, Charles M. Perou, C. Ryan Miller, Rachel Raab, Olufunmilayo I. Olopade & Kevin Gardner Nature Communications, doi:10.1038/ncomms2438 (2013)
Ischemic stroke is associated with the ABO locus: The EuroCLOT study FMK Williams, AM Carter, PG Hysi et al and EuroCLOT Investigators, the Wellcome Trust Case Control Consortium 2, MORGAM, MetaStroke and the International Stroke Genetics Consortium Annals of Neurology, DOI: 10.1002/ana.23838 (2013)
Initial Assessment of the Pathogenic Mechanisms of the Recently Identified Alzheimer Risk Loci P Holton, M Ryten, MA Nalls et al. Annals of Human Genetics, DOI: 10.1111/ahg.12000 (2013)
Alternative Complex III from phototrophic bacteria and its electron acceptor auracyanin Erica L.W. Majumder, Jeremy D. King, Robert E. Blankenship Biochim. et Biophys. Acta - Bioenergetics, doi://10.1016/j.bbabio.2013.01.008 (2013)
Identification of Early Replicating Fragile Sites that Contribute to Genome Instability JH Barlow, RB Faryabi, E Callen, N Wong, A Malhowski, H Tang Chen, G Gutierrez-Cruz, H-W Sun, P McKinnon, G Wright, R Casellas, DF Robbiani, L Staudt, O Fernandez-Capetillo, A Nussenzweig Cell, doi://10.1016/j.cell.2013.01.006 (2013)
Genetic variation associated with circulating monocyte count in the eMERGE Network DR Crosslin, A McDavid, N Weston et al Hum. Mol. Genetics, doi: 10.1093/hmg/ddt010 (2013)

PI(4,5)P2-Mediated Cell Signaling: Emerging Principles and PTEN as a Paradigm for Regulatory Mechanism Arne Gericke, Nicholas R. Leslie, Mathias Lösche, Alonzo H. Ross Adv Exp Med Biol, doi: 10.1007/978-94-007-6331-9_6 (2013)

2012 (144 papers)

An efficient algorithm for clustering of large-scale mass spectrometry data Saeed F, Pisitkun T, Knepper MA, Hoffert JD Proceedings (IEEE Int Conf Bioinformatics Biomed), doi://10.1109/BIBM.2012.6392738 (2012)
A Dual Polybasic Motif Determines Phosphoinositide Binding and Regulation in the P2X Channel Family Louis-Philippe Bernier, Dominique Blais, É ́ric Boué-Grabot, Philippe Séguéla PLoS One 7:1-9, doi: 10.1371/journal.pone.0040595 (2012)
Estimating Diagnostic Accuracy of Raters Without a Gold Standard by Exploiting a Group of Experts Zhang B, Chen Z, Albert PS. Biometrics, doi: 10.1111/j.1541-0420.2012.01789.x (2012)
Entropy of single-file water in (6,6) carbon nanotubes Aparna Waghe, Jayendran C. Rasaiah, and Gerhard Hummer J. Chem. Phys. , doi://10.1063/1.4737842 (2012)
Assessment of the Effect of 24-Hour Aldosterone Administration on Protein Abundance in Fluorescence-Sorted Mouse Distal Renal Tubules by Mass Spectrometry Jensen T.B., Pisitkun T., Hoffert J.D., Jensen U.B., Fenton R.A, Praetorius H.A, Knepper M.A, Praetorius J. Nephron Physiology, DOI:10.1159/000346832 (2012)
On the Origins of the Linear Free Energy Relationships: Exploring the Nature of the Off-Diagonal Coupling Elements in SN2 Reactions Edina Rosta and Arieh Warshal J Chem Theory Comput. , doi: 10.1021/ct2009329 (2012)
An efficient dynamic programming algorithm for phosphorylation site assignment of large-scale mass spectrometry data Fahad Saeed, Trairak Pisitkun, Jason D. Hoffert, Guanghui Wang, Marjan Gucek, and Mark A. Knepper Proceedings of IEEE Int Conf Bioinformatics Biomed, doi://10.1109/BIBMW.2012.6470210 (2012)
Cell population-specific expression analysis of human cerebellum A Kuhn, A Kumar, A Beilina, A Dillman, MR Cookson, AB Singleton BMC Genomics, doi:10.1186/1471-2164-13-610 (2012)
Both Genome Segments Contribute to the Pathogenicity of Very Virulent Infectious Bursal Disease Virus Olivier Escaffre, Cyril Le Nouën, Michel Amelot, Xavier Ambroggio, Kristen M. Ogden, Olivier Guionie, Didier Toquin, Hermann Müller, Mohammed R. Islam and Nicolas Eterradossi J. Virology, doi: 10.1128/JVI.02360-12 (2012)
Using dissociation energies to predict observability of b- and y-peaks in mass spectra of short peptides. II. Results for hexapeptides with non-polar side chains O. I. Obolensky, Wells W. Wu, Rong-Fong Shen, Yi-Kuo Yu Rapid Comm. in Mass. Spec., DOI: 10.1002/rcm.6451 (2012)
Melatonin inhibits matrix metalloproteinase-9 activity by binding to its active site Deep Sankar Rudra, Uttam Pal, Nakul Chandra Maiti, Russel J. Reiter, Snehasikta Swarnakar J. Pineal Research, DOI: 10.1111/jpi.12034 (2012)

RPA Accumulation during Class Switch Recombination Represents 5'-3' DNA-End Resection during the S-G2/M Phase of the Cell Cycle Arito Yamane, Davide F. Robbiani, Wolfgang Resch, Anne Bothmer, Hirotaka Nakahashi, Thiago Oliveira, Philipp C. Rommel, Eric J. Brown, Andre Nussenzweig, Michel C. Nussenzweig, Rafael Casellas Cell Reports, doi://10.1016/j.celrep.2012.12.006, (2012)
Molecular structures of trimeric HIV-1 Env in complex with small antibody derivatives Joel R. Meyerson, Erin E. H. Tran, Oleg Kuybeda, Weizao Chen, Dimiter S. Dimitrov, Andrea Gorlani, Theo Verrips, Jeffrey D. Lifson, and Sriram Subramaniam PNAS, doi:10.1073/pnas.1214810110 (2012)
Effect of compatible and noncompatible osmolytes on the enzymatic activity and thermal stability of bovine liver catalase H. Sepasi Tehrani, A.A. Moosavi-Movahedia, H. Ghourchian, F. Ahmad, A. Kiany, M.S. Atri, Sh Ariaeenejad, K. Kavousi & A.A. Sabourya J. Biomol. Struct. Dynamics, DOI:10.1080/07391102.2012.742460 (2012)
RNA Interference Mediated Inhibition of Dengue Virus Multiplication and Entry in HepG2 Cells MA Alhoot, SM Wang, SD Sekaran PLoS One, RNA Interference Mediated Inhibition of Dengue Virus Multiplication and Entry in HepG2 Cells (2012)
On the edge of web-based multiple sequence alignment services Nguyen, Ken D. Tsinghua Science and Technology 17(6):629-637 (2012)
Using dissociation energies to predict observability of b- and y-peaks in mass spectra of short peptides. O. I. Obolensky, Wells W. Wu, Rong-Fong Shen, Yi-Kuo Yu Rapid Comm. in Mass. Spec., DOI: 10.1002/rcm.6451 (2012)

Mechanisms for the Insertion of Toxic, Fibril-like β-Amyloid Oligomers into the Membrane Hyunbum Jang , Laura Connelly , Fernando Teran Arce , Srinivasan Ramachandran , Bruce L. Kagan , Ratnesh Lal , and Ruth Nussinov J. Chem. Theory Compt. , DOI: 10.1021/ct300916f (2012)
Structural Ensemble of an Intrinsically Disordered Polypeptide Jeetain Mittal , Tae Hyeon Yoo , George Georgiou , and Thomas Michael Truskett J. Phys. Chem. B, DOI: 10.1021/jp308984e (2012)
STATs Shape the Active Enhancer Landscape of T Cell Populations Golnaz Vahedi, Hayato Takahashi, Shingo Nakayamada, Hong-wei Sun, Vittorio Sartorelli, Yuka Kanno, John J. O'Shea Cell, doi://10.1016/j.cell.2012.09.044, (2012)
Screening system for orthogonal suppressor tRNAs based on the species-specific toxicity of suppressor tRNAs Hong Tian, Danni Deng, Jie Huang, Dongning Yao, Xiaowei Xu, Xiangdong Gao Biochimie, doi://10.1016/j.biochi.2012.12.010 (2012)
Structural and Mechanistic Investigations of Phosphothreonine Lyase Class of Enzymes Alok Gopalkrishna Shenoy Graduate Thesis, Utah State University (2012)
Evaluation of Gene Association Methods for Coexpression Network Construction and Biological Knowledge Discovery Sapna Kumari, Jeff Nie, Huann-Sheng Chen, Hao Ma, Ron Stewart, Xiang Li, Meng-Zhu Lu, William M. Taylor, Hairong Wei PLoS One, doi:10.1371/journal.pone.0050411 (2012)
Common genetic variation near the Connexin-43 gene is associated with resting heart rate in African Americans: A Genome-wide Association Study of 13,372 participants R Deo, MA Nalls, CL Avery, JG Smith et al. Heart Rhythm, doi://10.1016/j.hrthm.2012.11.014 (2012)
Protein Secondary Structure Determination by Constrained Single-Particle Cryo-Electron Tomography Alberto Bartesaghi, Federico Lecumberry, Guillermo Sapiro, Sriram Subramaniam Structure 20(12):2003-2013 (2012)
A Systematic Approach for Development of an OPLS-Like Force Field and Its Application to Hydrofluorocarbons Eugene Paulechka , Kenneth Kroenlein , Andrei Kazakov , and Michael Frenkel J. Phys. Chem. B, DOI: 10.1021/jp309119h (2012)
The Impact of Ancestry and Common Genetic Variants on QT Interval in African Americans JG Smith, CL Avery, DS Evans, MA Nalls et al. Circulation: Cardiovascular Genetics, doi: 10.1161/CIRCGENETICS.112.962787 (2012)
The effect of spatial smoothing on fMRI decoding of columnar-level organization with linear support vector machine Masaya Misaki, Wen-Ming Luh, Peter A. Bandettini J. Neuroscience Methods, doi://10.1016/j.jneumeth.2012.11.004 (2012)
Candidate Gene Association Study of BMI-Related Loci, Weight, and Adiposity in Old Age Rachel A. Murphy, Michael A. Nalls, Margaux Keller, Melissa Garcia, Stephen B. Kritchevsky, Frances A. Tylavsky, Anne B. Newman, Gregory J. Tranah, Gudny Eiriksdottir, Vilmundur Gudnason and Tamara B. Harris J. Gerontology A, doi: 10.1093/gerona/gls227 (2012)

Conformational Exploration of Two Peptides and Their Hybrid Polymer Conjugates: Potentialities as Self-Aggregating Materials Nurit Haspel, Adéle D. Laurent, David Zanuy , Ruth Nussinov, Carlos Aleman, Jordi Puiggali, and Guillermo Revilla-López J. Phys. Chem. B, DOI: 10.1021/jp3043363 (2012)
Watching a signaling protein function in real time via 100-ps time-resolved Laue crystallography F Schotte, HS Cho, VRI Kaila, H Kamikubo, N Dashdorj, ER Henry, TJ Graber, R Henning, M Wulff, G Hummer, M Kataoka, and PA Anfinrud PNAS, doi: 10.1073/pnas.1210938109 (2012)
Effects of the BDNF Val66Met Polymorphism on White Matter Microstructure in Healthy Adults H Tost, T Alam, M Geramita, C Rebsch, B Kolachana, D Dickinson, BA Verchinski, H Lemaitre, AS Barnett, JW Trampush, DR Weinberger and S Marenco Neuropsychopharmacology , doi: 10.1038/npp.2012.214 (2012)
Sodium and calcium mechanisms of rhythmic bursting in excitatory neural networks of the pre-Bötzinger complex: a computational modelling study Patrick E. Jasinski, Yaroslav I. Molkov, Natalia A. Shevtsova, Jeffrey C. Smith, Ilya A. Rybak Eur. J. Neuroscience, DOI: 10.1111/ejn.12042 (2012)
Effects of image contrast on functional MRI image registration Javier Gonzalez-Castillo, Kristen N. Duthie, Ziad S. Saad, Carlton Chu, Peter A. Bandettini, Wen-Ming Luh NeuroImage, doi://10.1016/j.neuroimage.2012.10.076 (2012)
Accurate decoding of sub-TR timing differences in stimulations of sub-voxel regions from multi-voxel response patterns Masaya Misaki, Wen-Ming Luh, Peter A. Bandettini NeuroImage, doi://10.1016/j.neuroimage.2012.10.069, (2012)

Novel Loci Associated with PR Interval in a Genome-Wide Association Study of Ten African American Cohorts AM Butler, X Yin, DS Evans, MA Nalls et al. Circulation: Cardiovascular Genetics, doi: 10.1161/CIRCGENETICS.112.963991 (2012)
Response of the Mitochondrial Proteome of Rat Renal Proximal Convoluted Tubules to Chronic Metabolic Acidosis D Freund, JE Prenni, NP Curthoys Renal Physiology, ,doi: 10.1152/ajprenal.00526.2012 (2012)
PTEN: An Intercellular Peacekeeper? Nick R. Leslie Science Signaling, DOI: 10.1126/scisignal.2003685 (2012)
Gene Silencing Mediated by siRNA-binding Fusion Proteins Is Attenuated by Double-stranded RNA-binding Domain Structure James C Geoghegan, Brian L Gilmore and Beverly L Davidson Molecular Therapy Nucleic Acids, doi:10.1038/mtna.2012.43 (2012)
A collaborative framework for 3D alignment and classification of heterogeneous subvolumes in cryo-electron tomography Oleg Kuybeda, Gabriel A. Frank, Alberto Bartesaghi, Mario Borgnia, Sriram Subramaniam , Guillermo Sapiro J. Struct. Biol. , doi://10.1016/j.jsb.2012.10.010 (2012)
Novel inhibitors of a Grb2 SH3C domain interaction identified by a virtual screen Philip C. Simister, James Luccarelli, Sam Thompson, Daniel H. Appella, Stephan M. Feller , Andrew D. Hamilton Bioorganic & Medicinal Chemistry, doi://10.1016/j.bmc.2012.10.023 (2012)

Statistical tests for detecting associations with groups of genetic variants: generalization, evaluation, and implementation John Ferguson, William Wheeler, YiPing Fu, Ludmila Prokunina-Olsson, Hongyu Zhao and Joshua Sampson Eur. J. Hum. Genetics, doi: 10.1038/ejhg.2012.220 (2012)
Imputation of Exome Sequence Variants into Population- Based Samples and Blood-Cell-Trait-Associated Loci in African Americans: NHLBI GO Exome Sequencing Project Paul L. Auer, Jill M. Johnsen, Andrew D. Johnson et al. Am. J. Hum. Genet., doi://10.1016/j.ajhg.2012.08.031 (2012)
SHAVE: shrinkage estimator measured for multiple visits increases power in GWAS of quantitative traits Osorio D Meirelles, Jun Ding, Toshiko Tanaka, Serena Sanna, Hsih-Te Yang, Dawood B Dudekula, Francesco Cucca, Luigi Ferrucci, Goncalo Abecasis and David Schlessinger European J. Hum. Genetics, doi: 10.1038/ejhg.2012.215 (2012)
Membrane Association of the PTEN Tumor Suppressor: Electrostatic Interaction with Phosphatidylserine-Containing Bilayers and Regulatory Role of the C-Terminal Tail Siddharth S. Shenoy, Hirsh Nanda, c, Mathias Lösche J. Struct. Biol. , doi://10.1016/j.jsb.2012.10.003, (2012)
Characterization of synonymous codon usage bias in the pseudorabies virus US1 gene Meili Li, Zhiyao Zhao, Jianhong Chen, Bingyun Wang, Zi Li, Jian Li and Mingsheng Cai Virologica Sinica, DOI: 10.1007/s12250-012-3270-9 (2012)
Overlapping ETS and CRE Motifs (G/CCGGAAGTGACGTCA) Preferentially Bound by GABPα and CREB Proteins Raghunath Chatterjee, Jianfei Zhao, Ximiao He, Andrey Shlyakhtenko, Ishminder Mann, Joshua J. Waterfall, Paul Meltzer, B. K. Sathyanarayana, Peter C. FitzGerald, Charles Vinson Genes | Genomes | Genetics, doi://10.1534/g3.112.004002 (2012)

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies M Traylor, M Farrall, EG Holliday et al & International Stroke Genetics Consortium The Lancet Neurology, doi://10.1016/S1474-4422(12)70234-X, (2012)
Siblings with Ischemic Stroke Study (SWISS): Results of a Genome-wide Scan for Stroke Loci JF. Meschia, M Nalls, M Matarin, TG. Brott, RD. Brown, Jr., J Hardy, B Kissela, SS. Rich, A Singleton, D Hernandez, L Ferrucci, K Pearce, M Keller, BB. Worrall, for the Siblings with Ischemic Stroke Study (SWISS) Investigators Stroke, doi: 10.1161/STROKEAHA.111.620484 (2012)
Effect of Complement CR1 on Brain Amyloid Burden During Aging and Its Modification byAPOEGenotype M Thambisetty, Y An, M Nalls et al for the Baltimore Longitudinal Study of Aging and the Alzheimer's Disease Neuroimaging Initiative Biological Psychiatry, doi://10.1016/j.biopsych.2012.08.015 (2012)
CPhos: a program to calculate and visualize evolutionarily conserved functional phosphorylation sites Boyang Zhao, Trairak Pisitkun, Jason D. Hoffert, Mark A. Knepper, Fahad Saeed Proteomics, DOI: 10.1002/pmic.201200189 (2012)
Quantitative Phosphoproteomics in Nuclei of Vasopressin-Sensitive Renal Collecting Duct Cells Steven J. Bolger, Patricia A. Gonzales Hurtado, Jason D. Hoffert, Fahad Saeed, Trairak Pisitkun, and Mark A. Knepper Am J Physiol Cell Physiol, doi:10.1152/ajpcell.00260.2012 (2012)
Are Myocardial Infarction-Associated Single-Nucleotide Polymorphisms Associated With Ischemic Stroke? Cheng YC, Anderson CD, Bione S et al Stroke, doi: 10.1161/STROKEAHA.111.632075 (2012)

Lin28b Reprograms Adult Bone Marrow Hematopoietic Progenitors to Mediate Fetal-Like Lymphopoiesis Joan Yuan, Cuong K. Nguyen, Xiuhuai Liu, Chrysi Kanellopoulou, Stefan A. Muljo Science 335 (6073):1195-1200 (2012)
Mouse model of endemic Burkitt translocations reveals the long-range boundaries of Ig-mediated oncogene deregulation AL Kovalchuk, C Ansarah-Sobrinho, O Hakim, W Resch, Helena Tolarová, W Dubois, A Yamane, M Takizawa, IKlein, GL Hager, HC Morse III, M Potter, MC Nussenzweig, and R Casellas PNAS, doi: 10.1073/pnas.1200106109 (2012)
Testing associations of copy number variations in genome-wide association studies Jianxin Shi and Peng Li Statistica Sinica, doi://10.5705/ss.2012.071s (2012)
Systems Biology in Physiology: The Vasopressin Signaling Network in Kidney Mark A. Knepper Am. J. Physiol. - Cell Physiol. , doi: 10.1152/ajpcell.00270.2012 (2012)
Comparing the Expected Misclassification Cost for Two Classifiers Based on Estimates From the Same Sample James F. Troendle, Kai F. Yu, Peter H. Westfall, Gene Pennello & Enrique F. Schisterman Statistics in Biopharmaceutical Research, DOI:10.1080/19466315.2012.695263 (2012)
Theory for cross effect dynamic nuclear polarization under magic-angle spinning in solid state nuclear magnetic resonance: The importance of level crossings Kent Thurber and Robert Tycko J. Chem. Phys. , doi://10.1063/1.4747449 (2012)

Prediction of variable translation rate effects on cotranslational protein folding Edward P. O'Brien, Michele Vendruscolo & Christopher M. Dobson Nature Communications, doi:10.1038/ncomms1850 (2012)
Directed evolution reveals requisite sequence elements in the functional expression of P450 2F1 in Escherichia coli JBYH Behrendorff, CD Moore, K-H Kim, D-H Kim, CA Smith, WA Johnston, C-H Yun, GS Yost, and EMJ Gillam Chemical Research in Toxicology, DOI: 10.1021/tx300281g (2012)
Using Genome-wide Complex Trait Analysis to quantify 'missing heritability' in Parkinson's disease MF Keller, M Saad, et al and International Parkinson's Disease Genomics Consortium and the Wellcome Trust Case Control Consortium 2 Human Molecular Genetics, doi: 10.1093/hmg/dds335 (2012)
Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics R Schmitz, RM Young et al Nature, doi:10.1038/nature11378 (2012)
Automated subcortical segmentation using FIRST: Test-retest reliability, interscanner reliability, and comparison to manual segmentation Allison C. Nugent, David A. Luckenbaugh, Suzanne E. Wood, Wendy Bogers, Carlos A. Zarate Jr., Wayne C Drevets Human Brain Mapping, DOI: 10.1002/hbm.22068 (2012)
Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone φ, ψ and Side-Chain χ1 and χ2 Dihedral Angles Robert B. Best, Xiao Zhu, Jihyun Shim, Pedro E. M. Lopes, Jeetain Mittal, Michael Feig, and Alexander D. MacKerell, Jr. J. Chem. Theory Comput., DOI: 10.1021/ct300400x (2012)

Profibrogenic chemokines and viral evolution predict rapid progression of hepatitis C to cirrhosis Patrizia Farci, Kurt Wollenberg, Giacomo Diaz, Ronald E. Engle, Maria Eliana Lai, Paul Klenerman, Robert H. Purcell, Oliver G. Pybus, and Harvey J. Alter PNAS, doi: 10.1073/pnas.1210592109 (2012)
Multiple Testing of Composite Null Hypotheses in Heteroscedastic Models Wenguang Sun & Alexander C. McLain Journal of the American Statistical Association 107(498):637-687 (2012)
Use of support vector machines for disease risk prediction in genome-wide association studies: Concerns and opportunities F Mittag, F Büchel, M Saad, A Jahn, C Schulte, Z Bochdanovits, J Simón-Sánchez, MA Nalls, M Keller, DG Hernandez, JR Gibbs, S Lesage, A Brice, P Heutink, M Martinez, NW Wood, J Hardy, AB Singleton, A Zell, T Gasser, M Sharma for the International Parkinson's Disease Genomics Consortium (IPDGC) Human Mutation, DOI: 10.1002/humu.22161 (2012)
Drying Transition in the Hydrophobic Gate of the GLIC Channel Blocks Ion Conduction Fangqiang Zhu and Gerhard Hummer Biophys. J. 103(2):219-227, doi://10.1016/j.bpj.2012.06.003 (2012)
Structural Mechanism of Trimeric HIV-1 Envelope Glycoprotein Activation Erin E. H. Tran, Mario J. Borgnia, Oleg Kuybeda, David M. Schauder, Alberto Bartesaghi, Gabriel A. Frank, Guillermo Sapiro, Jacqueline L. S. Milne, Sriram Subramaniam PLoS Pathogens, doi:10.1371/journal.ppat.1002797 (2012)
The impact of random-effect misspecification on percentile estimation for longitudinal growth data Kyeongmi Cheon, Paul S. Albert, Zhiwei Zhang Statistics in Medicine, DOI: 10.1002/sim.5437 (2012)
Mitochondrial DNA Sequence Variation Associated with Dementia and Cognitive Function in the Elderly Tranah GJ, Nalls MA, Katzman SM, Yokoyama JS, Lam ET, Zhao Y, Mooney S, Thomas F, Newman AB, Liu Y, Cummings SR, Harris TB, Yaffe K J. Alzheimer's Disease, doi://10.3233/JAD-2012-120466 (2012)
Weighted logrank tests for interval censored data when assessment times depend on treatment Michael P. Fay, Joanna H. Shih Statistics in Medicine, DOI: 10.1002/sim.5447 (2012)
Genetic Contributions to Individual Differences in Vulnerability to Addiction and Abilities to Quit George R. Uhl and Tomas Drgon in Drug Abuse and Addiction in Mental Illness, DOI: 10.1007/978-1-4614-3375-0-7 (2012)
Design and Assembly of Large Synthetic DNA Constructs Aleksandr E. Miklos, Randall A. Hughes, Andrew D. Ellington Current Protocols in Molecular Biology, DOI: 10.1002/0471142727.mb0323s99 (2012)
Leptin regulates dopamine responses to sustained stress in humans Paul R Burghardt, Tiffany M Love, Christian S. Stohler, Colin Hodgkinson, Pei-Hong Shen, Mary Ann Enoch, David Goldman, Jon-Kar Zubieta J. Neurosci. , doi: 10.1523/JNEUROSCI.2521-12.2012 (2012)
Estimating ancestral proportions in a multi-ethnic US sample: implications for studies of admixed populations Orna Levran, Olaoluwakitan Awolesi, Pei-Hong Shen, Miriam Adelson, and Mary Jeanne Kreek Human Genomics, doi: 10.1186/1479-7364-6-2 (2012)

The Peptide-Receptive Transition State of MHC Class I Molecules: Insight from Structure and Molecular Dynamics Michael G. Mage, Michael A. Dolan, Rui Wang, Lisa F. Boyd, Maria Jamela Revilleza, Howard Robinson, Kannan Natarajan, Nancy B. Myers, Ted H. Hansen and David H. Margulies J. Immunol. , doi: 10.4049/jimmunol.1200831 (2012)
The Folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for B cell development Baba M, Keller JR, Sun HW, Resch W, Kuchen S, Suh HC, Hasumi H, Hasumi Y, Kieffer-Kwon KR, Gonzalez CG, Hughes RM, Klein ME, Oh HF, Bible P, Southon E, Tessarollo L, Schmidt LS, Linehan WM, Casellas R. Blood, DOI 10.1182/blood-2012-02-410407 (2012)
Identifying Protein Kinase Target Preferences Using Mass Spectrometry Jacqueline Douglass, Ruwan Gunaratne, Davis Bradford, Fahad Saeed, Jason D. Hoffert, Peter J. Steinbach, Mark A. Knepper, and Trairak Pisitkun Cell Physiol., doi: 10.1152/ajpcell.00166.2012 (2012)
Improving the CHARMM Force Field for Polyunsaturated Fatty Acid Chains Jeffery B. Klauda, Viviana Monje, Taehoon Kim, and Wonpil Im J. Phys. Chem. B, DOI: 10.1021/jp304056p (2012)
Crystal structure of a plectonemic RNA supercoil Jason R. Stagno, Buyong Ma, Jess Li, Amanda S. Altieri, R. Andrew Byrd & Xinhua Ji Nature Communications, doi:10.1038/ncomms1903 (2012)
Codon optimization for high level expression of human bone morphogenetic protein-2 in Escherichia coli Debbie S. Retnoningruma, H.T. Pramestia, P.Y. Santikaa, O. Valeriusb, S. Asjariea, T. Suciatia Prot. Expr. and Pur., doi://10.1016/j.pep.2012.05.010 (2012)

Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases Sarah Baxter, Abigail R. Lambert, Ryan Kuhar, Jordan Jarjour, Nadia Kulshina, Fabio Parmeggiani, Patrick Danaher, Jacob Gano, David Baker, Barry L. Stoddard and Andrew M. Scharenberg Nucleic Acids Research, doi: 10.1093/nar/gks502 (2012)
Trigger factor slows co-translational folding through kinetic trapping while sterically protecting the nascent chain from aberrant cytosolic interactions Edward P O'Brien, John Christodoulou, Michele Vendruscolo, and Christopher M. Dobson J. Am. Chem. Soc. , DOI: 10.1021/ja302305u (2012)
Genomic Analysis of Immune Response against Vibrio cholerae Hemolysin in Caenorhabditis elegans Surasri N. Sahu, Jada Lewis, Isha Patel, Serdar Bozdag, Jeong H. Lee, Joseph E. LeClerc, and Hediye Nese Cinar PLoS One, doi: 10.1371/journal.pone.0038200 (2012)
Spontaneous High-Gamma Band Activity Reflects Functional Organization of Auditory Cortex in the Awake Macaque Makoto Fukushima, Richard C. Saunders, David A. Leopold, Mortimer Mishkin, and Bruno B. Averbeck Neuron, DOI 10.1016/j.neuron.2012.04.014 (2012)
Mitochondrial DNA sequence variation is associated with free-living activity energy expenditure in the elderly Gregory J. Tranah, Ernest T. Lam, Shana M. Katzman, Michael A. Nalls, Yiqiang Zhao, Daniel S. Evans, Jennifer S. Yokoyama, Ludmila Pawlikowska, Pui-Yan Kwok, Sean Mooney, Stephen Kritchevsky, Bret H. Goodpaster, Anne B. Newman, Tamara B. Harris, Todd M. Manini, Steven R. Cummings, For the Health, Aging and Body Composition Study Biochim. et Biophys. Acta - Bioenergetics, doi://10.1016/j.bbabio.2012.05.012 (2012)
An online tool for calculation of free-energy balance for the renal inner medulla Ryan L. Vilbig, Abhijit Sarkar, Joseph Zischkau, Mark A. Knepper, and Trairak Pisitkun Am. J. Physiol. , doi: 10.1152/ajprenal.00147.2012 (2012)

Application of systems biology principles to protein biomarker discovery: Urinary exosomal proteome in renal transplantation Trairak Pisitkun, Maria T. Gandolfo, Samarjit Das, Mark A. Knepper, Serena M. Bagnasco Proteomics -- Clinical Applications, doi://10.1002/prca.201100108 (2012)
Methods of adjusted comparison of medians James F. Troendle, Zhiwei Zhang, Megan E. Mathews, Junchi Guo Biometrical Journal, DOI: 10.1002/bimj.201100220 (2012)
Characterization of a Dynamic String Method for the Construction of Transition Pathways in Molecular Reactions Margaret E. Johnson and Gerhard Hummer J. Phys. Chem. B, DOI: 10.1021/jp212611k (2012)
Tissue-Specific Regulation of Chromatin Insulator Function Leah H. Matzat, Ryan K. Dale, Nellie Moshkovich, and Elissa P. Lei PLoS Genetics, doi: 10.1371/journal.pgen.1003069 (2012)
A Subset-Based Approach Improves Power and Interpretation for the Combined Analysis of Genetic Association Studies of Heterogeneous Traits Samsiddhi Bhattacharjee, Preetha Rajaraman, Kevin B. Jacobs, William A. Wheeler, Beatrice S. Melin, Patricia Hartge, GliomaScan Consortium, Meredith Yeager, Charles C. Chung, Stephen J. Chanock, Nilanjan Chatterjee Am. J. Hum. Genet., doi:/10.1016/j.ajhg.2012.03.015 (2012)
Seeing is believing: video classification for computed tomographic colonography using multiple-instance learning. Shijun Wang, Matthew T McKenna, Tan B Nguyen, Joseph E Burns, Nicholas Petrick, Berkman Sahiner, Ronald M Summers IEEE Transactions on Medical Imaging 31 (5):1141 (2012)

Cross-seeding and Conformational Selection between Three- and Four-repeat Human Tau Proteins Xiang Yu, Yin Luo, Paul Dinkel, Jie Zheng, Guanghong Wei, Martin Margittai, Ruth Nussinov, Buyong Ma J. Biol. Chem., doi: 10.1074/jbc.M112.340794 (2012)
An Integrative Segmentation Method for Detecting Germline Copy Number Variations in SNP Arrays Jianxin Shi, Peng Li Genetic Epidemiology 36(4):373-383, DOI: 10.1002/gepi.21631 (2012)
Structural and Functional Consequences of Phosphate-Arsenate Substitutions in Selected Nucleotides: DNA, RNA, and ATP Yu Xu, Buyong Ma, and Ruth Nussinov J. Phys. Chem. B, doi: 10.1021/jp300307u (2012)
Imino Hydrogen Positions in Nucleic Acids from Density Functional Theory Validated by NMR Residual Dipolar Couplings Alexander Grishaev, Jinfa Ying, Ad Bax J. Am. Chem. Soc., doi: 10.1021/ja301775j (2012)
The transcriptome of Spodoptera exigua larvae exposed to different types of microbes Laura Pascual, Agata K. Jakubowska, Jose M. Blanca, Joaquin Cañizares, Juan Ferré, Gernot Gloeckner, Heiko Vogel, Salvador Herrero Insect Biochem. Mol. Bio. , doi://10.1016/j.ibmb.2012.04.003 (2012)
A Two-Platform Design for Next Generation Genome-Wide Association Studies Joshua N. Sampson, Kevin Jacobs, Zhaoming Wang, Meredith Yeager, Stephen Chanock, Nilanjan Chatterjee Genetic Epidemiology, doi: 10.1002/gepi.21634 (2012)

Postnatal development-and age-related changes in DNA-methylation patterns in the human genome Paraskevi Salpea, Valya R. Russanova, Tazuko H. Hirai, Thomae G. Sourlingas, Kalliope E. Sekeri-Pataryas, Roberto Romero, Jonathan Epstein and Bruce H. Howard Nucleic Acids Research, doi: 10.1093/nar/gks312 (2012)
Restraints on backbone conformations in solid state NMR studies of uniformly labeled proteins from quantitative amide¹⁵N-¹⁵N and carbonyl ¹³C-¹³C dipolar recoupling data Kan-Nian Hua, Wei Qiang, Guillermo A. Bermejo, Charles D. Schwieters, Robert Tycko J. Magnetic Resonance, doi:10.1016/j.jmr.2012.03.001 (2012)
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis The Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium Lancet, doi: 10.1016/S0140-6736(12)60110-X (2012)
Distinct contributions of human hippocampal theta to spatial cognition and anxiety Brian R. Cornwell, Nicole Arkin, Cassie Overstreet, Frederick W. Carver, Christian Grillon Hippocampus, doi: 10.1002/hipo.22019 (2012)
Simple models of human brain functional networks Petra E. Vértes, Aaron F. Alexander-Bloch, Nitin Gogtay, Jay N. Giedd, Judith L. Rapoport, and Edward T. Bullmore PNAS, doi: 10.1073/pnas.1111738109 (2012)
Computational tools for metabolic engineering Wilbert B. Copeland, Bryan A. Bartley, Deepak Chandran, Michal Galdzicki, Kyung H. Kim, Sean C. Sleight, Costas D. Maranas, Herbert M. Sauro Metabolic Engineering, doi:10.1016/j.ymben.2012.03.001 (2012)
Nickel (II)-Schiff base complex recognizing domain II of bovine and human serum albumin: Spectroscopic and docking studies Aurkie Ray, Banabithi Koley Seth, Uttam Pal, Samita Basu Spectrochimica Acta Part A: Molecular and Biomolecular Spect, doi:10.1016/j.saa.2012.02.060 (2012)
Modular engineering of a microbially-produced viral capsomere vaccine for influenza Nani Wibowo, Yap P. Chuan, Linda H.L. Lua, Anton P.J. Middelberg Chemical Engineering Science, doi:10.1016/j.ces.2012.04.001 (2012)
Predicting kinase-substrate interactions in the era of proteomics. Focus on “Identifying protein kinase target preferences using mass spectrometry” Ewout J. Hoorn and Marcel E. Meima Am J. Phyiol. Cell Physiol., 10.1152/ajpcell.00232.2012 (2012)
Search and Analysis of Identical Reverse Octapeptides in Unrelated Proteins Konda Mani Saravanan, Samuel Selvaraj Genomics, Proteomics & Bioinformatics, doi://10.1016/j.gpb.2012.11.005 (2012)
Self-consistent treatment of the local dielectric permittivity and electrostatic potential in solution for polarizable macromolecular force fields Sergio A Hassan J. Chem. Phys. , doi://10.1063/1.4742910 (2012)
Effects of Point Substitutions on the Structure of Toxic Alzheimer's β-Amyloid Channels: Atomic Force Microscopy and Molecular Dynamics Simulations Connelly L, Jang H, Arce FT, Ramachandran S, Kagan BL, Nussinov R, Lal R. Biochemistry, doi: 10.1021/bi300257e (2012)

Quantitative Proteomics Identifies Vasopressin-Responsive Nuclear Proteins in Collecting Duct Cells. Laura K. Schenk, Steven J. Bolger, Kelli Luginbuhl, Patricia A. Gonzales, Markus M. Rinschen, Ming-Jiun Yu, Jason D. Hoffert, Trairak Pisitkun and Mark A. Knepper J. Am. Soc. Nephrology, doi: 10.1681/ASN.2011070738 (2012)
Whole-brain, time-locked activation with simple tasks revealed using massive averaging and model-free analysis Javier Gonzalez-Castillo, Ziad S. Saad, Daniel A. Handwerker, Souheil J. Inati, Noah Brenowitz, and Peter A. Bandettini PNAS, doi: 10.1073/pnas.1121049109 (2012)
Comprehensive Research Synopsis and Systematic Meta-Analyses in Parkinson's Disease Genetics: The PDGene Database Lill CM , Roehr JT , McQueen MB , Kavvoura FK , Bagade S , et al. PLoS Genetics, doi:10.1371/journal.pgen.1002548 (2012)
Unraveling the ORE1 Regulon in Arabidopsis thaliana: Molecular and Functional Characterization of Up- and Down-stream Components von Lilian Paola Matallana-Ramírez PhD Thesis, University of Potsdam (2012)
SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome BA Liu, BW Engelmann, K Jablonowski, K Higginbotham, AB Stergachis and PD Nash Cell Communication and Signaling 10:27 (2012)
Optimization and Modeling of Protein Refolding Conditions Bernd Rainer Kurt Anselment PhD Thesis, Institute of Biochemical Engineering of the Technische Universit�t M�nchen (2012)

Cooperative Genome-Wide Analysis Shows Increased Homozygosity in Early Onset Parkinson's Disease Simón-Sánchez J , Kilarski LL , Nalls MA , Martinez M , Schulte C , et al. PLoS One, doi:10.1371/journal.pone.0028787 (2012)
Stochastic Modeling for the Expression of a Gene Regulated by Competing Transcription Factors Hsih-Te Yang, Minoru S. H. Ko PLoS One, doi:10.1371/journal.pone.0032376 (2012)
Marginal analysis of longitudinal count data in long sequences: Methods and applications to a driving study Zhiwei Zhang, Paul S. Albert, and Bruce Simons-Morton Ann.Appl.Stat. 6(1):27-54 (2012)
Theory and simulation of ion conduction in the pentameric GLIC channel Fangqiang Zhu and Gerhard Hummer J. Chem. Theory and Computation, doi: 10.1021/ct2009279 (2012)
A Meta-Analysis and Genome-Wide Association Study of Platelet Count and Mean Platelet Volume in African Americans Qayyum R , Snively BM , Ziv E , Nalls MA , Liu Y , et al. PLoS Genetics, doi:10.1371/journal.pgen.1002491 (2012)
Distinct Regulatory Mechanisms and Functions for p53-Activated and p53-Repressed DNA Damage Response Genes in Embryonic Stem Cells Mangmang Li, Yunlong He, Wendy Dubois, Xiaolin Wu, Jianxin Shi, Jing Huang Molecular Cell, doi:10.1016/j.molcel.2012.01.020 (2012)
Modeling fecundity in the presence of a sterile fraction using a semi-parametric transformation model for grouped survival data Alexander McLain, Rajeshwari Sundaram, Germaine Buck Louis Stat. Meth. in Med. Res. , doi: 10.1177/0962280212438646 (2012)
Pair diffusion, hydrodynamic interactions, and available volume in dense fluids Jeetain Mittal, Gerhard Hummer arXiv preprint, arXiv:1202.6039 (2012)
Sensitive mapping of recombination hotspots using sequencing-based detection of ssDNA Pavel P Khil, Fatima Smagulova, Kevin M Brick, R. Daniel Camerini-Otero and Galina V Petukhova Genome Res., doi:10.1101/gr.130583.111 (2012)
A Bayesian approach to mixture cure models with spatial frailties for population-based cancer relative survival data Binbing Yu, Ram C. Tiwari Canadian Journal of Statistics, doi: 10.1002/cjs.10135 (2012)
Using DNAWorks in Designing Oligonucleotides for PCR-Based Gene Synthesis. David Hoover Methods in Molecular Biology 852(3):215-223 (2012)
Comparison of Common Homology Modeling Algorithms: Application of User-Defined Alignments. Michael A. Dolan, James W. Noah and Darrell Hurt Methods in Molecular Biology 857:399-414 (2012)

The elusive phosphotyrosine: pinning down a rare species. Focus on “Large-scale phosphotyrosine proteomic profiling of rat renal collecting duct epithelium reveals predominance of proteins involved in cell polarity determination Carolyn M. Ecelbarger Am J Physiol Cell Physiol January 302:C16-C17 (2012)
Computational separation of conformational heterogeneity using cryo-electron tomography and 3D sub-volume averaging Gabriel A. Frank, Alberto Bartesaghi, Oleg Kuybeda, Mario J. Borgnia, Tommi A. White, Guillermo Sapiro, Sriram Subramaniam J. Struct. Biol. , doi:/10.1016/j.jsb.2012.01.004 (2012)
A Joint Mixed Effects Dispersion Model for Menstrual Cycle Length and Time-to-Pregnancy Alexander C. McLain, Kirsten J. Lum, Rajeshwari Sundaram Biometrics, doi: 10.1111/j.1541-0420.2011.01711.x (2012)
PDB Ligand Conformational Energies Calculated Quantum-Mechanically Markus Sitzmann, Iwona Wedlich, Igor V Filippov, Chenzhong Liao, Megan L. Peach, Wolf-Dietrich Ihlenfeldt, Rajeshri G Karki, Yulia V Borodina, Raul E Cachau, and Marc C Nicklaus J. Chem. Inf. Model. , doi: 10.1021/ci200595n (2012)
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke The International Stroke Genetics Consortium (ISGC), the Wellcome Trust Case Control Consortium et al. Nature Genetics, doi:10.1038/ng.1081 (2012)
A simple recipe for the non-expert bioinformaticist for building experimentally-testable hypotheses for proteins with no known homologs Alexander Zawaira and Youtaro Shibayama J. Struct. Funct. Genomics, doi://10.1007/s10969-012-9141-7 (2012)

DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes Ofir Hakim, Wolfgang Resch, Arito Yamane, Isaac Klein, Kyong-Rim Kieffer-Kwon, Mila Jankovic, Thiago Oliveira, Anne Bothmer, Ty C. Voss, Camilo Ansarah-Sobrinho, Ewy Mathe, Genqing Liang, Jesse Cobell, Hirotaka Nakahashi, Davide F. Robbiani, Andre Nussenzweig, Gordon L. Hager, Michel C. Nussenzweig & Rafael Casellas Nature, doi:10.1038/nature10909 (2012)
Bubblegrams Reveal the Inner Body of Bacteriophage φKZ Weimin Wu, Julie A. Thomas, Naiqian Cheng, Lindsay W. Black, Alasdair C. Steven Science 335 (6065):182 (2012)
Integrated cross-species transcriptional network analysis of metastatic susceptibility Ying Hu, Gang Wu, Michael Rusch, Luanne Lukes, Kenneth H. Buetow, Jinghui Zhang, and Kent W. Hunter PNAS, doi: 10.1073/pnas.1117872109 (2012)
All-D-Enantiomer of β-Amyloid Peptide Forms Ion Channels in Lipid Bilayers Ricardo Capone, Hyunbum Jang, Samuel A Kotler, Laura S Connelly, Fernando Teran Arce, Srinivasan Ramachandran, Bruce L. Kagan, Ruth Nussinov, and Ratnesh Lal J. Chem. Theory and Computation, doi: 10.1021/ct200885r (2012)
Inositol phosphate-induced stabilization of inositol 1, 3, 4, 5, 6-pentakisphosphate 2-kinase and its role in substrate specificity Varin Gosein, Ting-Fung Leung, Oren Krajden, Gregory J. Miller Protein Science, doi: 10.1002/pro.2049 (2012)
Probing Structural Features of Alzheimer's β-Amyloid Pores in Bilayers Using Site-Specific Amino Acid Substitutions Ricardo Capone, Hyunbum Jang, Samuel A Kotler, Bruce L. Kagan, Ruth Nussinov, and Ratnesh Lal J. Phys. Chem. B, doi: 10.1021/bi2017427 (2012)

Atomic Force Microscopy and MD Simulations Reveal Pore-Like Structures of All-D-Enantiomer of Alzheimer's β-Amyloid Peptide: Relevance to the Ion Channel Laura S Connelly, Fernando Teran Arce, Hyunbum Jang, Ricardo Capone, Samuel A Kotler, Srinivasan Ramachandran, Bruce L. Kagan, Ruth Nussinov, and Ratnesh Lal J. Phys. Chem. B, doi: 10.1021/jp2108126 (2012)

2011 (131 papers)

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies International Parkinson Disease Genomics Consortium Lancet, doi: 10.1016/S0140-6736(10)62345-8 (2011)
Comparing statistical methods for removing seasonal variation from vitamin D measurements in case-control studies Hong Zhang, Jiyoung Ahn, and Kai Yu Statistics and its Interface 3:85-93 (2011)
Antimicrobial Protegrin-1 Forms Amyloid-Like Fibrils with Rapid Kinetics Suggesting a Functional Link Hyunbum Jang, Fernando Teran Arce, Mirela Mustata, Srinivasan Ramachandran, Ricardo Capone, Ruth Nussinov, Ratnesh Lal Biophys. J., doi: 10.1016/j.bpj.2011.01.072 (2011)
Quantifying Protein-Protein Interactions Within Noncovalent Complexes Using Electrospray Ionization Mass Spectrometry Elisabetta Boeri Erba, Konstantin Barylyuk, Yang Yang, and Renato Zenobi Anal. Chem. 83(24):9251-9259 (2011)
Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes Klein IA, Resch W, Jankovic M, Oliveira T, Yamane A, Nakahashi H, Di Virgilio M, Bothmer A, Nussenzweig A, Robbiani DF, Casellas R, Nussenzweig MC. Cell 147(1):95-106 (2011)

Recombination mapping using Boolean logic and high-density SNP genotyping for exome sequence filtering Thomas C. Markello, Ted Han, Hannah Carlson-Donohoe, Chidi Ahaghotu, Ursula Harper, MaryPat Jones, Settara Chandrasekharappa, Yair Anikster, David R. Adams, NISC Comparative Sequencing Program, William A. Gahl, Cornelius F. Boerkoel Mol. Genetics & Metabolism, doi:10.1016/j.ymgme.2011.12.014 (2011)
Independent component analysis of resting brain activity reveals transient modulation of local cortical processing by transcranial direct current stimulation. Venkatakrishnan A, Contreras-Vidal JL, Sandrini M, Cohen LG. Conf Proc IEEE Eng Med Biol Soc. Aug:8102-5 (2011)
The Anatomical Distance of Functional Connections Predicts Brain Network Topology in Health and Schizophrenia Aaron F. Alexander-Bloch, Petra E. Vértes, Reva Stidd, François Lalonde, Liv Clasen, Judith Rapoport, Jay Giedd, Edward T. Bullmore and Nitin Gogtay Cerebral Cortex, doi:10.1093/cercor/bhr388 (2011)
Parietofrontal integrity determines neural modulation associated with grasping imagery after stroke Ethan R. Buch, Amirali Modir Shanechi, Alissa D. Fourkas, Cornelia Weber, Niels Birbaumer and Leonardo G. Cohen Brain, doi:10.1093/brain/awr331 (2011)
Analysis of Biological Features Associated with Meiotic Recombination Hot and Cold Spots in Saccharomyces cerevisiae Loren Hansen, Nak-Kyeong Kim, Leonardo Mariño-Ramírez, David Landsman PLoS One, doi:10.1371/journal.pone.0029711 (2011)
Tryptic y++ Fragment Ion Distributions Are Guided by Coulombic Repulsion Karl K. Irikura, John K. Merle and Yamil Sim´n-Manso J. Am. Soc. Mass Spec., doi:10.1007/s13361-011-0293-7 (2011)

Structural models of TREK channels and their gating mechanism Adina L Milac, Andriy Anishkin, Sarosh N Fatakia, Carson C Chow, Sergei Sukharev, and H Robert Guy Channels, doi: 10.4161/chan.5.1.13905 (2011)
Overproduction of recombinant proteins in plants Erin Egelkrout, Vidya Rajan, John A. Howard Plant Science, doi:10.1016/j.plantsci.2011.12.005 (2011)
Expression, purification and characterization of recombinant human serine proteinase inhibitor Kazal-type 6 (SPINK6) in Pichia pastoris Hairong Lu, Jinjiang Huang, Guodong Li, Kuikui Ge, Hongyu Wu, Qingshan Huang Protein Expression and Purification, doi:10.1016/j.pep.2011.12.004 (2011)
Condensin dysfunction in human cells induces nonrandom chromosomal breaks in anaphase, with distinct patterns for both unique and repeated genomic regions Alexander Samoshkin, Stanimir Dulev, Dmitry Loukinov, Jeffrey A. Rosenfeld and Alexander V. Strunnikov Chromosoma Biology of the Nucleus, doi: 10.1007/s00412-011-0353-6 (2011)
Effects of pH on proteins: Predictions for ensemble and single molecule pulling experiments Edward P O'Brien , Bernard R. Brooks , and Devarajan Thirumalai JACS, doi: 10.1021/ja206557y (2011)
Inherited Variation at Chromosome 12p13. 33, Including RAD52, Influences the Risk of Squamous Cell Lung Carcinoma Jianxin Shi, Nilanjan Chatterjee, Melissa Rotunno, Yufei Wang, Angela C. Pesatori, Dario Consonni, Peng Li, William Wheeler, Peter Broderick, Marc Henrion, Timothy Eisen, Zhaoming Wang, Wei Chen, Qiong Dong, Demetrius Albanes, Michael Thun, Margaret R. Spitz, Pier Alberto Bertazzi, Neil E. Caporaso, Stephen J. Chanock, Christopher I. Amos, Richard S. Houlston and Maria Teresa Landi Cancer Discovery, doi: 10.1158/2159-8290.CD-11-024 (2011)
Causal Inference on Quantiles with an Obstetric Application Zhiwei Zhang, Zhen Chen, James F. Troendle, and Jun Zhang Biometrics, doi: 10.1111/j.1541-0420.2011.01712.x (2011)
Does feature selection improve classification accuracy? Impact of sample size and feature selection on classification using anatomical magnetic resonance images Carlton Chu, Ai-Ling Hsu, Kun-Hsien Chou, Peter Bandettini, Ching-Po Lin, , and the Alzheimer's Disease Neuroimaging Initiative NeuroImage, doi:10.1016/j.neuroimage.2011.11.066 (2011)
Structural basis of anthrax edema factor neutralization by a neutralizing antibody Michelle Makiya, Michael Dolan, Liane Agulto, Robert Purcell, Zhaochun Chen Biochem. Biophys. Res. Comm., doi:10.1016/j.bbrc.2011.11.108 (2011)
High-level expression and characterization of a highly thermostable chitosanase from Aspergillus fumigatus in Pichia pastoris Xiaomei Chen, Chao Zhai, Lixin Kang, Chunhua Li, Hong Yan, Yuling Zhou, Xiaolan Yu and Lixin Ma Biotech. Letters, doi: 10.1007/s10529-011-0816-0 (2011)
Determination of Molecular Structures of HIV Envelope Glycoproteins using Cryo-Electron Tomography and Automated Sub-tomogram Averaging. Joel R. Meyerson, Tommi A. White et al J. Visualized Experiments, doi: 10.3791/2770 (2011)
Interaction of Merocyanine 540 with Serum Albumins: Photophysical and Binding Studies Mousumi Banerjee, Uttam Pal, Arijita Subudhhi, Abhijit Chakrabarti, Samita Basu J. Photochemistry and Photobiology B, doi:10.1016/j.jphotobiol.2011.12.005 (2011)

Gene Expression Databases for Kidney Epithelial Cells Jennifer C. Huling, Trairak Pisitkun, Jae H. Song, Ming-Jiun Yu, Jason D. Hoffert, and Mark A. Knepper Am. J. Physiol. - Renal Physiol., doi: 10.?1152/?ajprenal.?00457.?2011 doi: 10.?1152/?ajprenal.?00457.?2011 (2011)
Dynamics of the G protein-coupled vasopressin V2 receptor signaling network revealed by quantitative phosphoproteomics Jason D. Hoffert, Trairak Pisitkun, Fahad Saeed, Jae V. Song, Chung-Lin Chou and Mark A. Knepper Mol. Cell Proteomics, doi: 10.1074/mcp.M111.014613 (2011)
Standard reactions for comparative rate studies: Experiments on the dehydrochlorination reactions of 2-chloropropane, chlorocyclopentane, and chlorocyclohexane Iftikhar A. Awan, Donald R. Burgess Jr., Wing Tsang, Jeffrey A. Manion Int. J. Chem. Kinetics, doi: 10.1002/kin.20566 (2011)
Convergence and error estimation in free energy calculations using the weighted histogram analysis method Fangqiang Zhu, Gerhard Hummer J. Comp. Chem. , doi: 10.1002/jcc.21989 (2011)
The discovery of population differences in network community structure: New methods and applications to brain functional networks in schizophrenia Aaron Alexander-Bloch, Renaud Lambiotte, Ben Roberts, Jay Giedd, Nitin Gogtay, Ed Bullmore NeuroImage, doi:10.1016/j.neuroimage.2011.11.035 (2011)
A linear mixed model for predicting a binary event from longitudinal data under random effects misspecification Paul S. Albert Stat. Med., doi: 10.1002/sim.4405 (2011)

Antimicrobial Properties of Amyloid Peptides Bruce Kagan , Hyunbum Jang , Ricardo Capone , Fernando Teran Arce , Srinivasan Ramachandran , Ratnesh Lal , and Ruth Nussinov Molecular Pharmaceutics, doi: 10.1021/mp200419b (2011)
Extensive chromatin remodelling and establishment of transcription factor 'hotspots' during early adipogenesis Rasmus Siersbæk, Ronni Nielsen, Sam John, Myong-Hee Sung, Songjoon Baek, Anne Loft, Gordon L Hager and Susanne Mandrup Embo J. , doi:10.1038/emboj.2011.65 (2011)
Material Properties of Matrix Lipids Determine Conformation and Intermolecular Reactivity of a Diacetylenic Phosphatidylcholine in the Lipid Bilayer Anu Puri , Hyunbum Jang , Amichai Yavlovich , Athar M Masood , Timothy D. Veenstra , Carlos Luna , Helim Aranda-Espinoza , Ruth Nussinov , and Robert Blumenthal Langmuir, doi: 10.1021/la203453x (2011)
Expressão e caracterização de fragmentos de anticorpos recominanes Anti-CD3 humano em Pichia pastoris Sousa, Victor Edgard Tavares Master's thesis, University of Brasilia (2011)
Genome-Wide Association Analysis of Ischemic Stroke in Young Adults Yu-Ching Cheng, Jeffrey R. O'Connel et al Genes | Genomes | Genetics, doi: 10.1534/g3.111.001164 (2011)
Three-Dimensional Structures of Soluble CD4-Bound States of Trimeric Simian Immunodeficiency Virus Envelope Glycoproteins Determined by Using Cryo-Electron Tomography Tommi A. White, Alberto Bartesaghi, Mario J. Borgnia, M. Jason V. de la Cruz, Rachna Nandwani, James A. Hoxie, Julian W. Bess, Jeffrey D. Lifson, Jacqueline L. S. Milne and Sriram Subramaniam J. Virol., doi: 10.1128/?JVI.05297-11 (2011)
Dehydratase Mediated 1-Propanol Production in Metabolically Engineered Escherichia coli. Rachit Jain, Yajun Yan Microbial Cell Factories, doi:10.1186/1475-2859-10-97 (2011)
The Histone Database: an integrated resource for histones and histone fold-containing proteins Leonardo Mariño-Ramírez, Kevin M. Levine, Mario Morales, Suiyuan Zhang, R. Travis Moreland, Andreas D. Baxevanis and David Landsman J. Biol. Databases and Curation, doi: 10.1093/database/bar048 (2011)
Water-Exclusion Effects and Liquid-Structure Forces in Implicit Solvation Sergio A Hassan and Peter J Steinbach J. Phys. Chem. B, doi: 10.1021/jp208184e (2011)
Impact of surface roughness on diffusion of confined fluids William P. Krekelberg, Vincent K. Shen, Jeffrey R. Errington, and Thomas M. Truskett J. Chem. Phys. , doi:10.1063/1.3651478 (2011)
An electrostatic switch controls palmitoylation of the large conductance voltage-and calcium-activated potassium (BK) channel Owen Jeffries, Lijun Tian, Heather McClafferty & Michael J. Shipston. J. Biol. Chem. , doi: 10.1074/jbc.M111.224840 (2011)
Energetics of direct and water-mediated proton-coupled electron transfer. Ville R. I. Kaila and Gerhard Hummer JACS, doi: 10.1021/ja2082262 (2011)

Resting and Active States of the ERK2: HePTP Complex Dana M. Francis, Bartosz Rózycki, Antoni Tortajada, Gerhard Hummer, Wolfgang Peti, and Rebecca Page JACS, doi: 10.1021/ja2075136 (2011)
Dynamic water networks in cytochrome cbb3 oxidase Vivek Sharma, Mårten Wikströma, Ville R.I. Kaila Biochim. et Biophys. Acta, doi:10.1016/j.bbabio.2011.09.010 (2011)
Identification, Replication, and Fine-Mapping of Loci Associated with Adult Height in Individuals of African Ancestry N'Diaye A, Chen GK et al. PLoS Genetics, doi:10.1371/journal.pgen.1002298 (2011)
Synthesis and bio-evaluation of human macrophage migration inhibitory factor inhibitor to develop anti-inflammatory agent Athar Alama, Chinmay Pala, Manish Goyala, Milan Kumar Kundub, Rahul Kumara, Mohd Shameel Iqbala, Sumanta Deya, Samik Bindua, Souvik Sarkara, Uttam Palc, Nakul C. Maitic, Susanta Adhikarid, Uday Bandyopadhyay Bioorganic and Medicinal Chemistry, doi:10.1016/j.bmc.2011.10.056 (2011)
Investigation of Anatomical Thalamo-Cortical Connectivity and fMRI Activation in Schizophrenia Stefano Marenco, Jason L Stein, Antonina A Savostyanova, Fabio Sambataro, Hao-Yang Tan, Aaron L Goldman, Beth A Verchinski, Alan S Barnett, Dwight Dickinson, José A Apud, Joseph H Callicott, Andreas Meyer-Lindenberg and Daniel R Weinberger Neuropsychopharmacology, doi: 10.1038/npp.2011.215 (2011)
NHLBI-AbDesigner: An online tool for design of peptide-directed antibodies Trairak Pisitkun, Jason D. Hoffert, Fahad Saeed, and Mark A. Knepper Am. J. Cell. Physiol. , doi: 10.1152/ajpcell.00325.201 (2011)

A coarse-grained model for PEGylated lipids: the effect of PEGylation on size and shape of self-assembled structures Hwankyu Lee, Richard W. Pastor J. Phys. Chem. B, doi: 10.1021/jp2020148 (2011)
Oncogenically active MYD88 mutations in human lymphoma V.N. Ngo, R.M. Young, R. Schmitz et al Nature, doi:10.1038/nature09671 (2011)
Overexpression of synthesized cephalosporin C acylase containing mutations in the substrate transport tunnel Ying Wang, Huimin Yu, Wensi Song, Ming An, Jing Zhang, Hui Luo, Zhongyao Shen J. Biosci. Bioeng., doi:10.1016/j.jbiosc.2011.08.027 (2011)
Capsomer Vaccines Protect Mice from Vaginal Challenge with Human Papillomavirus Wai-Hong Wu, Elizabeth Gersch, Kihyuck Kwak, Subhashini Jagu, Balasubramanyam Karanam, Warner K. Huh, Robert L. Garcea, Richard B. S. Roden PLoS One, doi:10.1371/journal.pone.0027141 (2011)
N-Protonated Isomers as Gateways to Peptide Ion Fragmentation Fredrik Haeffner, John K. Merle and Karl K. Irikura J. Am. Soc. Mass Spec., doi: 10.1007/s13361-011-0241-6 (2011)
PubChem3D: Biologically relevant 3-D similarity Sunghwan Kim , Evan E Bolton and Stephen H Bryant J. Cheminform., doi:10.1186/1758-2946-3-26 (2011)

Genomic Risk Profiling of Ischemic Stroke: Results of an International Genome-Wide Association Meta-Analysis James F. Meschia, Andrew Singleton, Michael A. Nalls, Stephen S. Rich, Pankaj Sharma, Luigi Ferrucci, Mar Matarin, Dena G. Hernandez, Kerra Pearce, Thomas G. Brott, Robert D. Brown Jr., John Hardy, Bradford B. Worrall PLoS One, doi:10.1371/journal.pone.0023161 (2011)
Large-Scale Phosphotyrosine Proteomic Profiling of Rat Renal Collecting Duct Epithelium Reveals Predominance of Proteins Involved in Cell Polarity Determination Boyang Zhao, Mark A. Knepper, Chung-Lin Chou, and Trairak Pisitkun Cell Physiol. , doi: 10.?1152/ajpcell.00300.2011 (2011)
Logistic regression analysis of biomarker data subject to pooling and dichotomization Z. Zhang, A. Liu, R.H., Lyles, B. Mukherjee Statistics in Medicine, doi: 10.1002/sim.4367 (2011)
Generalized degrees of freedom and adaptive model selection in linear mixed-effects models Bo Zhang, Xiaotong Shen, Sunni L. Mumford Comp. Stats & Data Anal., doi:10.1016/j.csda.2011.09.001 (2011)
Flexible cullins in cullin-ring E3 ligases allosterically regulate ubiquitination Jin Liu and Ruth Nussinov J. Biol. Chem. , doi: 10.1074/jbc.M111.277236 (2011)
Application of a yeast two-hybrid based screening system in the identification of amyloid-beta aggregation inhibitors in pharmaceutical plants Li-Wei Wang, Yan-Fang Yang, Ying-Tao Zhang J. Chinese Pharm. Sciences 20(5):510-517 (2011)
Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo Shehab A Ismail, Yong-Xiang Chen, Alexandra Rusinova, Anchal Chandra, Martin Bierbaum, Lothar Gremer, Gemma Triola, Herbert Waldmann, Philippe I H Bastiaens & Alfred Wittinghofer Nature Chem. Bio. , doi:10.1038/nchembio.686 (2011)
In silico implementation of synthetic gene networks. Mario Andrea Marchisio Methods in Mol. Bio. , doi: 10.1007/978-1-61779-412-4_1 (2011)
Selective cell-surface labeling of the molecular motor protein prestin Ryan M. McGuire, Jonathan J. Silberg, Fred A. Pereira, c, Robert M. Raphael Biochem. Biophys. Res. Comm., doi://10.1016/j.bbrc.2011.05.121 (2011)
The Core of Ure2p Prion Fibrils Is Formed by the N-Terminal Segment in a Parallel Cross-? Structure: Evidence from Solid-State NMR Dmitry S. Kryndushkin, Reed B. Wickner, Robert Tycko J. Mol. Biol. , doi://10.1016/j.jmb.2011.03.067 (2011)
Latent class models for joint analysis of disease prevalence and high-dimensional semicontinuous biomarker data Bo Zhang, Zhen Chen and Paul S. Albert Biostatistics, doi: 10.1093/biostatistics/kxr024 (2011)
White Matter Microstructural Correlates of Superior Long-term Skill Gained Implicitly under Randomized Practice Sunbin Song, Nikhil Sharma, Ethan R. Buch and Leonardo G. Cohen Cerebral Cortex, doi: 10.1093/cercor/bhr247 (2011)

Genetic Association for Renal Traits among Participants of African Ancestry Reveals New Loci for Renal Function C-T Liu, MK Garnaas et al. PLoS Genetics, doi:10.1371/journal.pgen.1002264 (2011)
A Network-Based Approach to Prioritize Results from Genome-Wide Association Studies N. Akula, A. Baranova, D Seto, J Solka, MA Nalls, A Singleton, L Ferrucci, T Tanaka, S Bandinelli, YS Cho, YJ Kim, J-Y Lee, B-G Han, Bipolar Disorder Genome Study (BiGS) Consortium, The Wellcome Trust Case-Control Consortium, FJ McMahon PLoS One, doi:10.1371/journal.pone.0024220 (2011)
Conditional Allele Mouse Planner (CAMP): software to facilitate the planning and design of breeding strategies involving mice with conditional alleles Jason D. Hoffert, Trairak Pisitkun, R. Lance Miller. Transgenic Research, doi: 10.1007/s11248-011-9545-3 (2011)
Tackling Force-Field Bias in Protein Folding Simulations: Folding of Villin HP35 and Pin WW Domains in Explicit Water Jeetain MIttal and Robert B. Best