Papers that used NIH HPC (Biowulf) resources
If you have published research that has made significant use of these systems, please let us know by sending email to staff@hpc.nih.gov
2024 to date (431 papers)
- RNA helicase D1PAS1 resolves R-loops and forms a complex for mouse pachytene piRNA biogenesis required for male fertility Choi, H; Zhou, L; Zhao, Y; Dean, J; , Nucleic Acids Res, DOI://10.1093/nar/gkae712 (2024)
- Cryo-EM structure of a natural prion: chronic wasting disease fibrils from deer Alam, P; Hoyt, F; Artikis, E et al. Acta Neuropathol, DOI://10.1007/s00401-024-02813-y (2024)
- The Bor1 elevator transport cycle is subject to autoinhibition and activation Jiang, Y; Jiang, J; , Nat Commun, DOI://10.1038/s41467-024-53411-1 (2024)
- MYB/MYBL1-altered gliomas frequently harbor truncations and non-productive fusions in the MYB and MYBL1 genes Chung, HJ; Rajan, S; Wu, Z et al. Acta Neuropathol, DOI://10.1007/s00401-024-02803-0 (2024)
- Altruistic feeding and cell-cell signaling during bacterial differentiation actively enhance phenotypic heterogeneity Updegrove, TB; Delerue, T; Anantharaman, V et al. Sci Adv, DOI://10.1126/sciadv.adq0791 (2024)
- The Myc-associated zinc finger protein epigenetically controls expression of interferon-γ-stimulated genes by recruiting STAT1 to chromatin Xiao, T; Li, X; Felsenfeld, G; , Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2320938121 (2024)
- Targeting SWI/SNF ATPases reduces neuroblastoma cell plasticity Xu, M; Hong, JJ; Zhang, X et al. EMBO J, DOI://10.1038/s44318-024-00206-1 (2024)
- A machine learning model reveals expansive downregulation of ligand-receptor interactions that enhance lymphocyte infiltration in melanoma with developed resistance to immune checkpoint blockade Sahni, S; Wang, B; Wu, D et al. Nat Commun, DOI://10.1038/s41467-024-52555-4 (2024)
- SMARCD1 is an essential expression-restricted metastasis modifier Ross, C; Gong, LY; Jenkins, LM et al. Commun Biol, DOI://10.1038/s42003-024-07018-3 (2024)
- Highly efficient generation of self-renewing trophoblast from human pluripotent stem cells Slamecka, J; Ryu, S; Tristan, CA et al. iScience, DOI://10.1016/j.isci.2024.110874 (2024)
- Unsupervised Multi-parametric MRI Registration Using Neural Optimal Transport Kim, B; Mathai, TS; Summers, RM; , Proc SPIE Int Soc Opt Eng, DOI://10.1117/12.3006289 (2024)
- Early Detection of Malignant and Premalignant Peripheral Nerve Tumors Using Cell-Free DNA Fragmentomics Sundby, RT; Szymanski, JJ; Pan, AC et al. Clin Cancer Res, DOI://10.1158/1078-0432.CCR-24-0797 (2024)
- Mutational signatures in 175 Chinese gastric cancer patients Liu, F; Hu, N; Jiang, K et al. BMC Cancer, DOI://10.1186/s12885-024-12968-2 (2024)
- Automated Classification of Multi-parametric Body MRI Series Kim B, Mathai TS, Helm K, Summers RM IEEE International Symposium on Biomedical Imaging, https://doi.org/10.1109/ISBI56570.2024.10635686 (2024)
- Normalization of Fronto-Parietal Activation by Cognitive-Behavioral Therapy in Unmedicated Pediatric Patients With Anxiety Disorders Haller, SP; Linke, JO; Grassie, HL et al. Am J Psychiatry, DOI://10.1176/appi.ajp.20220449 (2024)
- PARP-1 selectively impairs KRAS-driven phenotypic and molecular features in intrahepatic cholangiocarcinoma Keggenhoff, FL; Castven, D; Becker, D et al. Gut, DOI://10.1136/gutjnl-2023-331237 (2024)
- Structure of Amyloid Peptide Ribbons Characterized by Electron Microscopy, Atomic Force Microscopy, and Solid-State Nuclear Magnetic Resonance Thurber, KR; Yau, WM; Tycko, R; , J Phys Chem B, DOI://10.1021/acs.jpcb.3c07867 (2024)
- Disease flares with baricitinib dose reductions and development of flare criteria in patients with CANDLE/PRAAS Cetin Gedik, K; Ortega-Villa, AM; Materne, G et al. Ann Rheum Dis, DOI://10.1136/ard-2023-225463 (2024)
- A deep-learning framework to predict cancer treatment response from histopathology images through imputed transcriptomics Hoang, DT; Dinstag, G; Shulman, ED et al. Nat Cancer, DOI://10.1038/s43018-024-00793-2 (2024)
- A Multiomic Analysis to Identify Drivers of Subclinical Vascular Disease in Systemic Lupus Erythematosus Oliveira, C; Temesgen-Oyelakin, Y; Naqi, M et al. Arthritis Rheumatol, DOI://10.1002/art.42925 (2024)
- Enrichment of Rare Variants of Hemophagocytic Lymphohistiocytosis Genes in Systemic Juvenile Idiopathic Arthritis Correia Marques, M; Rubin, D; Shuldiner, EG et al. Arthritis Rheumatol, DOI://10.1002/art.42938 (2024)
- OVO positively regulates essential maternal pathways by binding near the transcriptional start sites in the Drosophila female germline Benner, L; Muron, S; Gomez, JG; Oliver, B; , Elife, DOI://10.7554/eLife.94631 (2024)
- Impact of HLA class I functional divergence on HIV control Viard, M; O'hUigin, C; Yuki, Y et al. Science, DOI://10.1126/science.adk0777 (2024)
- Segmentation of mediastinal lymph nodes in CT with anatomical priors Mathai, TS; Liu, B; Summers, RM; , Int J Comput Assist Radiol Surg, DOI://10.1007/s11548-024-03165-4 (2024)
- Enhanced muscle and fat segmentation for CT-based body composition analysis: a comparative study Hou, B; Mathai, TS; Liu, J et al. Int J Comput Assist Radiol Surg, DOI://10.1007/s11548-024-03167-2 (2024)
- Emergence of transmissible SARS-CoV-2 variants with decreased sensitivity to antivirals in immunocompromised patients with persistent infections Nooruzzaman, M; Johnson, KEE; Rani, R et al. Nat Commun, DOI://10.1038/s41467-024-51924-3 (2024)
- LIM-domain-only 4 (LMO4) enhances CD8+ T-cell stemness and tumor rejection by boosting IL-21-STAT3 signaling Schelker, RC; Fioravanti, J; Mastrogiovanni, F et al. Signal Transduct Target Ther, DOI://10.1038/s41392-024-01915-z (2024)
- Adoptive transfer of personalized neoantigen-reactive TCR-transduced T cells in metastatic colorectal cancer: phase 2 trial interim results Parkhurst, M; Goff, SL; Lowery, FJ et al. Nat Med, DOI://10.1038/s41591-024-03109-0 (2024)
- On the role of the UMLS in supporting diagnosis generation proposed by Large Language Models Afshar, M; Gao, Y; Gupta, D et al. J Biomed Inform, DOI://10.1016/j.jbi.2024.104707 (2024)
- Cell type- and transcription-independent spatial proximity between enhancers and promoters Mian, Y; Wang, L; Keikhosravi, A et al. Mol Biol Cell, DOI://10.1091/mbc.E24-02-0082 (2024)
- In vivo mapping of the mouse Galnt3-specific O-glycoproteome Dalal, K; Yang, W; Tian, E et al. J Biol Chem, DOI://10.1016/j.jbc.2024.107628 (2024)
- HOXD12 defines an age-related aggressive subtype of oligodendroglioma Nuechterlein, N; Cimino, S; Shelbourn, A et al. Acta Neuropathol, DOI://10.1007/s00401-024-02802-1 (2024)
- Context-aware single-cell multiomics approach identifies cell-type-specific lung cancer susceptibility genes Long, E; Yin, J; Shin, JH et al. Nat Commun, DOI://10.1038/s41467-024-52356-9 (2024)
- Sexually dimorphic renal expression of mouse Klotho is directed by a kidney-specific distal enhancer responsive to HNF1b Jankowski, J; Lee, HK; Liu, C et al. Commun Biol, DOI://10.1038/s42003-024-06855-6 (2024)
- A Set of FMRI Quality Control Tools in AFNI: Systematic, in-depth, and interactive QC with afni_proc.py and more Taylor, PA; Glen, DR; Chen, G et al. Imaging Neurosci (Camb), DOI://10.1162/imag_a_00246 (2024)
- A sex-stratified analysis of the genetic architecture of human brain anatomy Shafee, R; Moraczewski, D; Liu, S et al. Nat Commun, DOI://10.1038/s41467-024-52244-2 (2024)
- Thermodynamics-inspired explanations of artificial intelligence Mehdi, S; Tiwary, P; , Nat Commun, DOI://10.1038/s41467-024-51970-x (2024)
- Bromodomain protein BRD4 directs mitotic cell division of mouse fibroblasts by inhibiting DNA damage Wu, T; Hou, H; Dey, A et al. iScience, DOI://10.1016/j.isci.2024.109797 (2024)
- PKR activation-induced mitochondrial dysfunction in HIV-transgenic mice with nephropathy Yoshida, T; Latt, KZ; Rosenberg, AZ et al. Elife, DOI://10.7554/eLife.91260 (2024)
- Genomic approach to determine sources of neonatal Staphylococcus aureus infection from carriage in the Gambia Bojang, A; Chung, M; Camara, B et al. BMC Infect Dis, DOI://10.1186/s12879-024-09837-5 (2024)
- Estimation of inbreeding and kinship coefficients via latent identity-by-descent states Guan, Y; Levy, D; , Bioinformatics, DOI://10.1093/bioinformatics/btae082 (2024)
- Generation of antitumor chimeric antigen receptors incorporating T cell signaling motifs Balagopalan, L; Moreno, T; Qin, H et al. Sci Signal, DOI://10.1126/scisignal.adp8569 (2024)
- De Novo Genome Assemblies From Two Indigenous Americans from Arizona Identify New Polymorphisms in Non-Reference Sequences Köroğlu, Ç; Chen, P; Traurig, M et al. Genome Biol Evol, DOI://10.1093/gbe/evae188 (2024)
- Innate protection against intrarectal SIV acquisition by a live SHIV vaccine Sui, Y; Meyer, TJ; Fennessey, CM et al. JCI Insight, DOI://10.1172/jci.insight.175800 (2024)
- Highly sensitive mapping of in vitro type II topoisomerase DNA cleavage sites with SHAN-seq Morgan, IL; McKie, SJ; Kim, R et al. Nucleic Acids Res, DOI://10.1093/nar/gkae638 (2024)
- Genome-Wide and Transcriptome-Wide Association Studies on Northern New England and Ohio Amyotrophic Lateral Sclerosis Cohorts Li, S; Gui, J; Passarelli, MN et al. Neurol Genet, DOI://10.1212/NXG.0000000000200188 (2024)
- Germline pathogenic variants in neuroblastoma patients are enriched in BARD1 and predict worse survival Kim, J; Vaksman, Z; Egolf, LE et al. J Natl Cancer Inst, DOI://10.1093/jnci/djad183 (2024)
- The association of GNB5 with Alzheimer disease revealed by genomic analysis restricted to variants impacting gene function Zhang, J; Pandey, M; Awe, A et al. Am J Hum Genet, DOI://10.1016/j.ajhg.2024.01.005 (2024)
- Insights into the mechanisms and structure of breakage-fusion-bridge cycles in cervical cancer using long-read sequencing Rodriguez, I; Rossi, NM; Keskus, AG et al. Am J Hum Genet, DOI://10.1016/j.ajhg.2024.01.002 (2024)
- Inferring Characteristics of the Tumor Immune Microenvironment of Patients with HNSCC from Single-Cell Transcriptomics of Peripheral Blood Cao, Y; Chang, T; Schischlik, F et al. Cancer Res Commun, DOI://10.1158/2767-9764.CRC-24-0092 (2024)
- Softening in Two-Component Lipid Mixtures by Spontaneous Curvature Variance Hossein, A; Beaven, AH; Sapp, K; Sodt, AJ; , J Phys Chem B, DOI://10.1021/acs.jpcb.3c08117 (2024)
- Salivary Gland Tissue Recombination Can Modify Cell Fate Sekiguchi, R; Martin, D; Doyle, AD et al. J Dent Res, DOI://10.1177/00220345241247484 (2024)
- Gα13 restricts nutrient driven proliferation in mucosal germinal centers Nguyen, HT; Li, M; Vadakath, R et al. Nat Immunol, DOI://10.1038/s41590-024-01910-0 (2024)
- An enhancer RNA recruits KMT2A to regulate transcription of Myb Kim, J; Diaz, LF; Miller, MJ et al. Cell Rep, DOI://10.1016/j.celrep.2024.114378 (2024)
- Crystal structure and mechanistic studies of the PPM1D serine/threonine phosphatase catalytic domain Kumar, JP; Kosek, D; Durell, SR et al. J Biol Chem, DOI://10.1016/j.jbc.2024.107561 (2024)
- Weakly supervised detection of pheochromocytomas and paragangliomas in CT using noisy data Oluigbo, D; Mathai, TS; Santra, B et al. Comput Med Imaging Graph, DOI://10.1016/j.compmedimag.2024.102419 (2024)
- Deep learning and direct sequencing of labeled RNA captures transcriptome dynamics Martinek, V; Martin, J; Belair, C et al. NAR Genom Bioinform, DOI://10.1093/nargab/lqae116 (2024)
- Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation Patel, VN; Aure, MH; Choi, SH et al. Nat Commun, DOI://10.1038/s41467-024-51862-0 (2024)
- CD28 hinge used in chimeric antigen receptor (CAR) T-cells exhibits local structure and conformational exchange amidst global disorder Folimonova, V; Chen, X; Negi, H et al. Commun Biol, DOI://10.1038/s42003-024-06770-w (2024)
- Paralogue-Selective Degradation of the Lysine Acetyltransferase EP300 Chen, X; Crawford, MC; Xiong, Y et al. JACS Au, DOI://10.1021/jacsau.4c00442 (2024)
- Evidence of association between higher cardiorespiratory fitness and higher cerebral myelination in aging Faulkner, ME; Gong, Z; Bilgel, M et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2402813121 (2024)
- Identification and functional validation of rare coding variants in genes linked to monogenic obesity Köroğlu, Ç; Traurig, M; Muller, YL et al. Obesity (Silver Spring), DOI://10.1002/oby.24101 (2024)
- The immune factors involved in the rapid clearance of bacteria from the midgut of the tick Ixodes ricinus Guizzo, MG; Frantová, H; Lu, S et al. Front Cell Infect Microbiol, DOI://10.3389/fcimb.2024.1450353 (2024)
- Tyrosine phosphorylation of both STAT5A and STAT5B is necessary for maximal IL-2 signaling and T cell proliferation Lin, JX; Ge, M; Liu, CY et al. Nat Commun, DOI://10.1038/s41467-024-50925-6 (2024)
- Unbiased discovery of cancer pathways and therapeutics using Pathway Ensemble Tool and Benchmark Wang, L; Pattnaik, A; Sahoo, SS et al. Nat Commun, DOI://10.1038/s41467-024-51859-9 (2024)
- An ANXA11 P93S variant dysregulates TDP-43 and causes corticobasal syndrome Snyder, A; Ryan, VH; Hawrot, J et al. Alzheimers Dement, DOI://10.1002/alz.13915 (2024)
- Time- and cell-specific activation of BMP signaling restrains chondrocyte hypertrophy Gadomski, SJ; Mui, BWH; Gorodetsky, R et al. iScience, DOI://10.1016/j.isci.2024.110537 (2024)
- Endogenous EWSR1 Exists in Two Visual Modalities That Reflect Its Associations with Nucleic Acids and Concentration at Sites of Active Transcription Sundara Rajan, S; Ebegboni, VJ; Pichling, P et al. Mol Cell Biol, DOI://10.1080/10985549.2024.2315425 (2024)
- POU4F3 Is Necessary for Normal Merkel Cell Formation, whereas POU4F1 Is Dispensable Jarvis, JE; Miao, L; Hallaert, P et al. J Invest Dermatol, DOI://10.1016/j.jid.2024.06.1284 (2024)
- Staufen1 Represses the FOXA1-Regulated Transcriptome by Destabilizing FOXA1 mRNA in Colorectal Cancer Cells Pasterczyk, KR; Li, XL; Singh, R et al. Mol Cell Biol, DOI://10.1080/10985549.2024.2307574 (2024)
- AlphaFold predictions of fold-switched conformations are driven by structure memorization Chakravarty, D; Schafer, JW; Chen, EA et al. Nat Commun, DOI://10.1038/s41467-024-51801-z (2024)
- Detection of ac4C in human mRNA is preserved upon data reassessment Beiki, H; Sturgill, D; Arango, D et al. Mol Cell, DOI://10.1016/j.molcel.2024.03.018 (2024)
- DNA polymerase swapping in Caudoviricetes bacteriophages Yutin, N; Tolstoy, I; Mutz, P et al. Virol J, DOI://10.1186/s12985-024-02482-z (2024)
- Taurine-conjugated bile acids and their link to hepatic S1PR2 play a significant role in hepatitis C-related liver disease Ali, RO; Haddad, JA; Quinn, GM et al. Hepatol Commun, DOI://10.1097/HC9.0000000000000478 (2024)
- The Time-Dependent Association Between Irritable Bowel Syndrome and All-Cause and Cause-Specific Mortality: A Prospective Cohort Study Within the UK Biobank Li, F; Yano, Y; Étiévant, L et al. Am J Gastroenterol, DOI://10.14309/ajg.0000000000002675 (2024)
- Genomic Underpinnings of Cytoplasmic Incompatibility: CIF Gene-Neighborhood Diversification Through Extensive Lateral Transfers and Recombination in Wolbachia Tan, Y; Aravind, L; Zhang, D; , Genome Biol Evol, DOI://10.1093/gbe/evae171 (2024)
- Childhood obesity's effect on cognition and brain connectivity worsens with low family income Tomasi, D; Volkow, ND; , JCI Insight, DOI://10.1172/jci.insight.181690 (2024)
- Immunosuppressive CD29+ Treg accumulation in the liver in mice on checkpoint inhibitor therapy Green, BL; Myojin, Y; Ma, C et al. Gut, DOI://10.1136/gutjnl-2023-330024 (2024)
- Tumor-derived RHOA mutants interact with effectors in the GDP-bound state Lin, Y; Ramelot, TA; Senyuz, S et al. Nat Commun, DOI://10.1038/s41467-024-51445-z (2024)
- PLCG2-associated immune dysregulation (PLAID) comprises broad and distinct clinical presentations related to functional classes of genetic variants Baysac, K; Sun, G; Nakano, H et al. J Allergy Clin Immunol, DOI://10.1016/j.jaci.2023.08.036 (2024)
- Pharmacologic ascorbate induces transient hypoxia sensitizing pancreatic ductal adenocarcinoma to a hypoxia activated prodrug Kishimoto, S; Crooks, DR; Yasunori, O et al. Free Radic Biol Med, DOI://10.1016/j.freeradbiomed.2024.07.008 (2024)
- Mutant mice with rod-specific VPS35 deletion exhibit retinal α-synuclein pathology-associated degeneration Fu, C; Yang, N; Chuang, JZ et al. Nat Commun, DOI://10.1038/s41467-024-50189-0 (2024)
- CAR T-cells targeting FGFR4 and CD276 simultaneously show potent antitumor effect against childhood rhabdomyosarcoma Tian, M; Wei, JS; Cheuk, AT et al. Nat Commun, DOI://10.1038/s41467-024-50251-x (2024)
- Exome copy number variant detection, analysis, and classification in a large cohort of families with undiagnosed rare genetic disease Lemire, G; Sanchis-Juan, A; Russell, K et al. Am J Hum Genet, DOI://10.1016/j.ajhg.2024.03.008 (2024)
- Deep Learning Segmentation of Ascites on Abdominal CT Scans for Automatic Volume Quantification Hou, B; Lee, S; Lee, JM et al. Radiol Artif Intell, DOI://10.1148/ryai.230601 (2024)
- Retracing the evolution of Pneumocystis species, with a focus on the human pathogen Pneumocystis jirovecii Cissé, OH; Ma, L; Kovacs, JA; , Microbiol Mol Biol Rev, DOI://10.1128/mmbr.00202-22 (2024)
- Structure and repair of replication-coupled DNA breaks Pavani, R; Tripathi, V; Vrtis, KB et al. Science, DOI://10.1126/science.ado3867 (2024)
- The recovery of parabolic avalanches in spatially subsampled neuronal networks at criticality Srinivasan, K; Ribeiro, TL; Kells, P; Plenz, D; , Sci Rep, DOI://10.1038/s41598-024-70014-4 (2024)
- Comprehensive Proteomics Analysis of the Hemolymph Composition of Sugar-Fed Aedes aegypti Female and Male Mosquitoes Alvarenga, PH; Alves E Silva, TL; Suzuki, M et al. J Proteome Res, DOI://10.1021/acs.jproteome.3c00918 (2024)
- Novel signals and polygenic score for height are associated with pubertal growth traits in Southwestern American Indians Ramírez-Luzuriaga, MJ; Kobes, S; Hsueh, WC et al. Hum Mol Genet, DOI://10.1093/hmg/ddae030 (2024)
- The landscape of etiological patterns of hepatocellular carcinoma and intrahepatic cholangiocarcinoma in Thailand Pupacdi, B; Loffredo, CA; Budhu, A et al. Int J Cancer, DOI://10.1002/ijc.35034 (2024)
- Emergency Myelopoiesis Distinguishes Multisystem Inflammatory Syndrome in Children From Pediatric Severe Coronavirus Disease 2019 Roznik, K; Andargie, TE; Johnston, TS et al. J Infect Dis, DOI://10.1093/infdis/jiae032 (2024)
- Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD Seddighi, S; Qi, YA; Brown, AL et al. Sci Transl Med, DOI://10.1126/scitranslmed.adg7162 (2024)
- ETS1, a Target Gene of the EWSR1::FLI1 Fusion Oncoprotein, Regulates the Expression of the Focal Adhesion Protein TENSIN3 Ebegboni, VJ; Jones, TL; Brownmiller, T et al. Mol Cancer Res, DOI://10.1158/1541-7786.MCR-23-1090 (2024)
- Maternal age is related to offspring DNA methylation: A meta-analysis of results from the PACE consortium Yeung, E; Biedrzycki, RJ; Gómez Herrera, LC et al. Aging Cell, DOI://10.1111/acel.14194 (2024)
- ModDotPlot-rapid and interactive visualization of tandem repeats Sweeten, AP; Schatz, MC; Phillippy, AM; , Bioinformatics, DOI://10.1093/bioinformatics/btae493 (2024)
- Comparative Evaluation of LLMs in Clinical Oncology Rydzewski, NR; Dinakaran, D; Zhao, SG et al. NEJM AI, DOI://10.1056/aioa2300151 (2024)
- TGF-β neutralization attenuates tumor residency of activated T cells to enhance systemic immunity in mice Fay, M; Sievers, C; Robbins, Y et al. iScience, DOI://10.1016/j.isci.2024.110520 (2024)
- Molecular Characterization of Metastatic Oncocytoma With Exceptional Response to Treatment: A Case Report Webster, BR; Ricketts, CJ; Vocke, CD et al. JCO Precis Oncol, DOI://10.1200/PO.24.00188 (2024)
- Predicting Survival in Mucinous Adenocarcinoma of the Appendix: Demographics, Disease Presentation, and Treatment Methodology McClelland, PH; Gregory, SN; Nah, SK et al. Ann Surg Oncol, DOI://10.1245/s10434-024-15526-z (2024)
- The Role of Interferon-γ in Autoimmune Polyendocrine Syndrome Type 1 Oikonomou, V; Smith, G; Constantine, GM et al. N Engl J Med, DOI://10.1056/NEJMoa2312665 (2024)
- Slower CDK4 and faster CDK2 activation in the cell cycle Zhang, W; Liu, Y; Jang, H; Nussinov, R; , Structure, DOI://10.1016/j.str.2024.04.012 (2024)
- Lack of genetic evidence for NLRP3 inflammasome involvement in Parkinson's disease pathogenesis Senkevich, K; Liu, L; Alvarado, CX et al. NPJ Parkinsons Dis, DOI://10.1038/s41531-024-00744-9 (2024)
- High-throughput image processing software for the study of nuclear architecture and gene expression Keikhosravi, A; Almansour, F; Bohrer, CH et al. Sci Rep, DOI://10.1038/s41598-024-66600-1 (2024)
- Combination Targeted Therapy in Relapsed Diffuse Large B-Cell Lymphoma Melani, C; Lakhotia, R; Pittaluga, S et al. N Engl J Med, DOI://10.1056/NEJMoa2401532 (2024)
- Renal Mitochondrial ATP Transporter Ablation Ameliorates Obesity-Induced CKD Permyakova, A; Hamad, S; Hinden, L et al. J Am Soc Nephrol, DOI://10.1681/ASN.0000000000000294 (2024)
- 3D chromatin architecture, BRD4, and Mediator have distinct roles in regulating genome-wide transcriptional bursting and gene network Trzaskoma, P; Jung, S; Pękowska, A et al. Sci Adv, DOI://10.1126/sciadv.adl4893 (2024)
- Motive and opportunity: MYC rearrangements in high-grade B-cell lymphoma with MYC and BCL2 rearrangements (an LLMPP study) Hilton, LK; Collinge, B; Ben-Neriah, S et al. Blood, DOI://10.1182/blood.2024024251 (2024)
- Acceptors stability modulates the efficiency of post-translational protein N-glycosylation Couto, PM; Guardia, CMA; Couto, FL et al. FASEB J, DOI://10.1096/fj.202302267R (2024)
- New discoveries in the genetics and genomics of systemic juvenile idiopathic arthritis Correia Marques, M; Ombrello, MJ; Schulert, GS; , Expert Rev Clin Immunol, DOI://10.1080/1744666X.2024.2345868 (2024)
- Loss of tumor suppressors promotes inflammatory tumor microenvironment and enhances LAG3+T cell mediated immune suppression Zahraeifard, S; Xiao, Z; So, JY et al. Nat Commun, DOI://10.1038/s41467-024-50262-8 (2024)
- Long-term health outcomes associated with hydration status Dmitrieva, NI; Boehm, M; Yancey, PH; Enhörning, S; , Nat Rev Nephrol, DOI://10.1038/s41581-024-00817-1 (2024)
- Single-Cell Characterization of the Tumor Ecosystem in Liver Cancer Wang, L; Revsine, M; Wang, XW; Ma, L; , Methods Mol Biol, DOI://10.1007/978-1-0716-3694-7_12 (2024)
- EncoMPASS: An encyclopedia of membrane proteins analyzed by structure and symmetry Aleksandrova, AA; Sarti, E; Forrest, LR; , Structure, DOI://10.1016/j.str.2024.01.011 (2024)
- Genome-Wide Analysis Identifies Nuclear Factor 1C as a Novel Transcription Factor and Potential Therapeutic Target in SCLC Shukla, V; Wang, H; Varticovski, L et al. J Thorac Oncol, DOI://10.1016/j.jtho.2024.03.023 (2024)
- A CTCF-binding site in the Mdm1-Il22-Ifng locus shapes cytokine expression profiles and plays a critical role in early Th1 cell fate specification Liu, C; Nagashima, H; Fernando, N et al. Immunity, DOI://10.1016/j.immuni.2024.04.007 (2024)
- The Aconitate Decarboxylase 1/Itaconate Pathway Modulates Immune Dysregulation and Associates with Cardiovascular Disease Markers and Disease Activity in Systemic Lupus Erythematosus Patiño-Martinez, E; Nakabo, S; Jiang, K et al. J Immunol, DOI://10.4049/jimmunol.2400241 (2024)
- In vitro identification of neutralizing epitopes of Rhipicephalus microplus serpin 17 (RmS-17) de Albuquerque, PMM; Kotál, J; Juliano, MA et al. Vaccine, DOI://10.1016/j.vaccine.2024.126161 (2024)
- An AI-generated proteome-scale dataset of predicted protein structures for the ctenophore Mnemiopsis leidyi Moreland, RT; Zhang, S; Barreira, SN et al. Proteomics, DOI://10.1002/pmic.202300397 (2024)
- The DNA Methyltransferase Inhibitor 5-Aza-4'-thio-2'-Deoxycytidine Induces C>G Transversions and Acute Lymphoid Leukemia Development Bertoli, RM; Chung, YJ; Difilippantonio, MJ et al. Cancer Res, DOI://10.1158/0008-5472.CAN-23-2785 (2024)
- Single-cell profiling identifies a CD8bright CD244bright Natural Killer cell subset that reflects disease activity in HLA-A29-positive birdshot chorioretinopathy Nath, PR; Maclean, M; Nagarajan, V et al. Nat Commun, DOI://10.1038/s41467-024-50472-0 (2024)
- Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut Das, A; Martinez-Ruiz, GU; Bouladoux, N et al. Immunity, DOI://10.1016/j.immuni.2024.04.001 (2024)
- OTMorph: Unsupervised Multi-domain Abdominal Medical Image Registration Using Neural Optimal Transport Kim, B; Zhuang, Y; Mathai, TS; Summers, RM; , IEEE Trans Med Imaging, DOI://10.1109/TMI.2024.3437295 (2024)
- IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma Bolomsky, A; Ceribelli, M; Scheich, S et al. Cancer Cell, DOI://10.1016/j.ccell.2024.05.026 (2024)
- Reproducible preclinical models of androgen receptor driven human prostate cancer bone metastasis Yin, J; Daryanani, A; Lu, F et al. Prostate, DOI://10.1002/pros.24718 (2024)
- The modification landscape of Pseudomonas aeruginosa tRNAs Mandler, MD; Maligireddy, SS; Guiblet, WM et al. RNA, DOI://10.1261/rna.080004.124 (2024)
- Harnessing diversity to study Alzheimer's disease: A new iPSC resource from the NIH CARD and ADNI Screven, LA; Pantazis, CB; Andersh, KM et al. Neuron, DOI://10.1016/j.neuron.2024.01.026 (2024)
- Chemoreactive 2,5-Diketopiperazines from a Penicillium sp., Structure Revision of Reported Analogues and Proposed Facile Transformation Pathways Khong, QT; Smith, EA; Wendt, KL et al. J Nat Prod, DOI://10.1021/acs.jnatprod.4c00478 (2024)
- Genetic and environmental interactions contribute to immune variation in rewilded mice Oyesola, O; Downie, AE; Howard, N et al. Nat Immunol, DOI://10.1038/s41590-024-01862-5 (2024)
- Cell-Free DNA Maps Tissue Injury and Correlates with Disease Severity in Lung Transplant Candidates Balasubramanian, S; Richert, ME; Kong, H et al. Am J Respir Crit Care Med, DOI://10.1164/rccm.202306-1064OC (2024)
- Exploring the midgut physiology of the non-haematophagous mosquito Toxorhynchites theobaldi Barbosa, RC; Godoy, RSM; Ferreira, PG et al. Open Biol, DOI://10.1098/rsob.230437 (2024)
- Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission Jimah, JR; Kundu, N; Stanton, AE et al. Dev Cell, DOI://10.1016/j.devcel.2024.04.008 (2024)
- Gene body DNA hydroxymethylation restricts the magnitude of transcriptional changes during aging Occean, JR; Yang, N; Sun, Y et al. Nat Commun, DOI://10.1038/s41467-024-50725-y (2024)
- Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation Wu, Y; Qin, K; Xu, Y et al. Elife, DOI://10.7554/eLife.84532 (2024)
- Metabolism-focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer Furusawa, T; Cavero, R; Liu, Y et al. Mol Carcinog, DOI://10.1002/mc.23705 (2024)
- Brain Functional Connectome Defines a Transdiagnostic Dimension Shared by Cognitive Function and Psychopathology in Preadolescents Xiao, X; Hammond, C; Salmeron, BJ et al. Biol Psychiatry, DOI://10.1016/j.biopsych.2023.08.028 (2024)
- The three-sided right-handed β-helix is a versatile fold for glycan interactions Burnim, AA; Dufault-Thompson, K; Jiang, X; , Glycobiology, DOI://10.1093/glycob/cwae037 (2024)
- Allosteric Activation of RhoA Complexed with p115-RhoGEF Deciphered by Conformational Dynamics Haspel, N; Jang, H; Nussinov, R; , J Chem Inf Model, DOI://10.1021/acs.jcim.3c01412 (2024)
- Lipid Trolling to Optimize A3 Adenosine Receptor-Positive Allosteric Modulators (PAMs) Pradhan, B; Pavan, M; Fisher, CL et al. J Med Chem, DOI://10.1021/acs.jmedchem.4c00944 (2024)
- Specialized replication of heterochromatin domains ensures self-templated chromatin assembly and epigenetic inheritance Nathanailidou, P; Dhakshnamoorthy, J; Xiao, H et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2315596121 (2024)
- Deafness DFNB128 Associated with a Recessive Variant of Human MAP3K1 Recapitulates Hearing Loss of Map3k1-Deficient Mice Faridi, R; Yousaf, R; Inagaki, S et al. Genes (Basel), DOI://10.3390/genes15070845 (2024)
- A whole-genome CRISPR screen identifies the spindle accessory checkpoint as a locus of nab-paclitaxel resistance in a pancreatic cancer cell line Mondal, P; Alyateem, G; Mitchell, AV; Gottesman, MM; , Sci Rep, DOI://10.1038/s41598-024-66244-1 (2024)
- An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II Zhao, H; Li, J; Xiang, Y et al. Mol Cell, DOI://10.1016/j.molcel.2024.06.006 (2024)
- Human neuroimaging and antipsychotic neurobiology at millisecond temporal resolution Eisenberg, DP; Berman, KF; , Neuropsychopharmacology, DOI://10.1038/s41386-024-01933-z (2024)
- Sickle cell allele HBB-rs334(T) is associated with decreased risk of childhood Burkitt lymphoma in East Africa Hong, HG; Gouveia, MH; Ogwang, MD et al. Am J Hematol, DOI://10.1002/ajh.27149 (2024)
- Genetic distance and ancestry proportion modify the association between maternal genetic risk score of type 2 diabetes and fetal growth Habtewold, TD; Wijesiriwardhana, P; Biedrzycki, RJ; Tekola-Ayele, F; , Hum Genomics, DOI://10.1186/s40246-024-00645-1 (2024)
- Host obesity impacts genetic variation in influenza A viral populations Knoll, M; Honce, R; Meliopoulos, V et al. J Virol, DOI://10.1128/jvi.01778-23 (2024)
- SIV infection and ARV treatment reshape the transcriptional and epigenetic profile of naïve and memory T cells in vivo Rahmberg, AR; Markowitz, TE; Mudd, JC et al. J Virol, DOI://10.1128/jvi.00283-24 (2024)
- Weakly-Supervised Detection of Bone Lesions in CT Sheng, T; Mathai, TS; Shieh, A; Summers, RM; , Proc SPIE Int Soc Opt Eng, DOI://10.1117/12.3008823 (2024)
- The landscape of rare genetic variants in familial Waldenström macroglobulinemia Pemov, A; Kim, J; Luo, W et al. Blood Neoplasia, DOI://10.1016/j.bneo.2024.100013 (2024)
- Response to Bruton's tyrosine kinase inhibitors in aggressive lymphomas linked to chronic selective autophagy Phelan, JD; Scheich, S; Choi, J et al. Cancer Cell, DOI://10.1016/j.ccell.2023.12.019 (2024)
- Epigenetic Age Mediates the Association of Life's Essential 8 With Cardiovascular Disease and Mortality Carbonneau, M; Li, Y; Prescott, B et al. J Am Heart Assoc, DOI://10.1161/JAHA.123.032743 (2024)
- Plasma Extracellular MicroRNAs Associated With Cardiovascular Disease Risk Factors in Middle-Aged and Older Adults Karlin, H; Sooda, M; Larson, M et al. J Am Heart Assoc, DOI://10.1161/JAHA.123.033674 (2024)
- Identification and structural characterization of a mutant KRAS-G12V specific TCR restricted by HLA-A3 Sim, MJW; Hanada, KI; Stotz, Z et al. Eur J Immunol, DOI://10.1002/eji.202451079 (2024)
- Whole-genome sequence of Mucor velutinosus NIH1002, a strain associated with disseminated disease Conlan, S; Subramanian, P; Plata Barril, B et al. Microbiol Resour Announc, DOI://10.1128/mra.00062-24 (2024)
- Mriyaviruses: small relatives of giant viruses Yutin, N; Mutz, P; Krupovic, M; Koonin, EV; , mBio, DOI://10.1128/mbio.01035-24 (2024)
- Transkingdom Network Analysis (TkNA): a systems framework for inferring causal factors underlying host-microbiota and other multi-omic interactions Newman, NK; Macovsky, MS; Rodrigues, RR et al. Nat Protoc, DOI://10.1038/s41596-024-00960-w (2024)
- Papillary tumor of the pineal region: analysis of DNA methylation profiles and clinical outcomes in 76 cases Wu, Z; Dazelle, K; Abdullaev, Z et al. Acta Neuropathol Commun, DOI://10.1186/s40478-024-01781-4 (2024)
- 2-Substituted (N)-Methanocarba A3 Adenosine Receptor Agonists: In Silico, In Vitro, and In Vivo Characterization Tosh, DK; Pavan, M; Cronin, C et al. ACS Pharmacol Transl Sci, DOI://10.1021/acsptsci.4c00223 (2024)
- Epigenome-wide association study of lung cancer among never smokers in two prospective cohorts in Shanghai, China Rahman, ML; Breeze, CE; Shu, XO et al. Thorax, DOI://10.1136/thorax-2023-220352 (2024)
- K128 ubiquitination constrains RAS activity by expanding its binding interface with GAP proteins Magits, W; Steklov, M; Jang, H et al. EMBO J, DOI://10.1038/s44318-024-00146-w (2024)
- Chronic Alcohol Intake Compromises Lung Immunity by Altering Immunometabolism in Humans and Mouse Models Pommerolle, L; Arif, M; Behee, M et al. Am J Respir Cell Mol Biol, DOI://10.1165/rcmb.2024-0086OC (2024)
- Inhibition of JAK-STAT pathway corrects salivary gland inflammation and interferon driven immune activation in Sjögren's disease Gupta, S; Yamada, E; Nakamura, H et al. Ann Rheum Dis, DOI://10.1136/ard-2023-224842 (2024)
- Whole-exome sequencing of Nigerian benign prostatic hyperplasia reveals increased alterations in apoptotic pathways White, JA; Kaninjing, ET; Adeniji, KA et al. Prostate, DOI://10.1002/pros.24662 (2024)
- Pleiotropic effects of an eQTL in the CELSR2/PSRC1/SORT1 cluster that associates with LDL-C and resting metabolic rate Bandesh, K; Freeland, K; Traurig, M et al. J Clin Endocrinol Metab, DOI://10.1210/clinem/dgae498 (2024)
- Genome-scale exon perturbation screens uncover exons critical for cell fitness Xiao, MS; Damodaran, AP; Kumari, B et al. Mol Cell, DOI://10.1016/j.molcel.2024.05.024 (2024)
- Preclinical Therapeutic Efficacy of RAF/MEK/ERK and IGF1R/AKT/mTOR Inhibition in Neuroblastoma Stauffer, S; Roth, JS; Hernandez, ER et al. Cancers (Basel), DOI://10.3390/cancers16132320 (2024)
- Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 h Grenko, CM; Taylor, HJ; Bonnycastle, LL et al. Diabetologia, DOI://10.1007/s00125-024-06214-4 (2024)
- Characterization of tumor evolution by functional clonality and phylogenetics in hepatocellular carcinoma Kacar, Z; Slud, E; Levy, D et al. Commun Biol, DOI://10.1038/s42003-024-06040-9 (2024)
- Evaluation of the Therapeutic Potential of Sulfonyl Urea Derivatives as Soluble Epoxide Hydrolase (sEH) Inhibitors Kundu, B; Dvorácskó, S; Basu, A et al. Molecules, DOI://10.3390/molecules29133036 (2024)
- Diagnosing Progression in Glioblastoma-Tackling a Neuro-Oncology Problem Using Artificial-Intelligence-Derived Volumetric Change over Time on Magnetic Resonance Imaging to Examine Progression-Free Survival in Glioblastoma Belue, MJ; Harmon, SA; Chappidi, S et al. Diagnostics (Basel), DOI://10.3390/diagnostics14131374 (2024)
- The gut-brain axis in individuals with alcohol use disorder: An exploratory study of associations among clinical symptoms, brain morphometry, and the gut microbiome Maki, KA; Wallen, GR; Bastiaanssen, TFS et al. Alcohol Clin Exp Res (Hoboken), DOI://10.1111/acer.15346 (2024)
- The phage shock protein (PSP) envelope stress response: discovery of novel partners and evolutionary history Ravi, J; Anantharaman, V; Chen, SZ et al. mSystems, DOI://10.1128/msystems.00847-23 (2024)
- Protein phosphatase 6 activates NF-κB to confer sensitivity to MAPK pathway inhibitors in KRAS- and BRAF-mutant cancer cells Zhang, H; Read, A; Cataisson, C et al. Sci Signal, DOI://10.1126/scisignal.add5073 (2024)
- Endogenous retroviruses are dysregulated in ALS Pasternack, N; Doucet-O'Hare, T; Johnson, K et al. iScience, DOI://10.1016/j.isci.2024.110147 (2024)
- Microenvironment shapes small-cell lung cancer neuroendocrine states and presents therapeutic opportunities Desai, P; Takahashi, N; Kumar, R et al. Cell Rep Med, DOI://10.1016/j.xcrm.2024.101610 (2024)
- The contribution of silencer variants to human diseases Huang, D; Ovcharenko, I; , Genome Biol, DOI://10.1186/s13059-024-03328-1 (2024)
- Allele-level visualization of transcription and chromatin by high-throughput imaging Almansour, F; Keikhosravi, A; Pegoraro, G; Misteli, T; , Histochem Cell Biol, DOI://10.1007/s00418-024-02289-7 (2024)
- The homeobox transcription factor DUXBL controls exit from totipotency Vega-Sendino, M; Lüttmann, FF; Olbrich, T et al. Nat Genet, DOI://10.1038/s41588-024-01692-z (2024)
- Distinct uptake and elimination profiles for trastuzumab, human IgG, and biocytin-TMR in experimental HER2+ brain metastases of breast cancer Silvestri, VL; Tran, AD; Chung, M et al. Neuro Oncol, DOI://10.1093/neuonc/noae025 (2024)
- Transcriptional Heterogeneity Overcomes Super-Enhancer Disrupting Drug Combinations in Multiple Myeloma Welsh, SJ; Barwick, BG; Meermeier, EW et al. Blood Cancer Discov, DOI://10.1158/2643-3230.BCD-23-0062 (2024)
- Chromosome segregation during spermatogenesis occurs through a unique center-kinetic mechanism in holocentric moth species Hockens, C; Lorenzi, H; Wang, TT et al. PLoS Genet, DOI://10.1371/journal.pgen.1011329 (2024)
- The Methyltransferases METTL7A and METTL7B Confer Resistance to Thiol-Based Histone Deacetylase Inhibitors Robey, RW; Fitzsimmons, CM; Guiblet, WM et al. Mol Cancer Ther, DOI://10.1158/1535-7163.MCT-23-0144 (2024)
- Untargeted metabolomic profiling reveals molecular signatures associated with type 2 diabetes in Nigerians Doumatey, AP; Shriner, D; Zhou, J et al. Genome Med, DOI://10.1186/s13073-024-01308-5 (2024)
- PubTator 3.0: an AI-powered literature resource for unlocking biomedical knowledge Wei, CH; Allot, A; Lai, PT et al. Nucleic Acids Res, DOI://10.1093/nar/gkae235 (2024)
- Potential association between suicide risk, aggression, impulsivity, and the somatosensory system Lee, Y; Gilbert, JR; Waldman, LR et al. Soc Cogn Affect Neurosci, DOI://10.1093/scan/nsae041 (2024)
- Modulation of biophysical properties of nucleocapsid protein in the mutant spectrum of SARS-CoV-2 Nguyen, A; Zhao, H; Myagmarsuren, D et al. Elife, DOI://10.7554/eLife.94836 (2024)
- Identification of intracellular bacteria from multiple single-cell RNA-seq platforms using CSI-Microbes Robinson, W; Stone, JK; Schischlik, F et al. Sci Adv, DOI://10.1126/sciadv.adj7402 (2024)
- A selective CutMix approach improves generalizability of deep learning-based grading and risk assessment of prostate cancer Patkar, S; Harmon, S; Sesterhenn, I et al. J Pathol Inform, DOI://10.1016/j.jpi.2024.100381 (2024)
- FASN Gene Methylation is Associated with Fatty Acid Synthase Expression and Clinical-genomic Features of Prostate Cancer Dairo, O; DePaula Oliveira, L; Schaffer, E et al. Cancer Res Commun, DOI://10.1158/2767-9764.CRC-23-0248 (2024)
- Genetic Risk Factors for Early-Onset Merkel Cell Carcinoma Mohsin, N; Hunt, D; Yan, J et al. JAMA Dermatol, DOI://10.1001/jamadermatol.2023.5362 (2024)
- Enhanced ac4C detection in RNA via chemical reduction and cDNA synthesis with modified dNTPs Relier, S; Schiffers, S; Beiki, H; Oberdoerffer, S; , RNA, DOI://10.1261/rna.079863.123 (2024)
- Structural basis of MALAT1 RNA maturation and mascRNA biogenesis Skeparnias, I; Bou-Nader, C; Anastasakis, DG et al. Nat Struct Mol Biol, DOI://10.1038/s41594-024-01340-4 (2024)
- The oxidation of the [4Fe-4S] cluster of DNA primase alters the binding energies with DNA and RNA primers Amin, M; Brooks, BR; , Biophys J, DOI://10.1016/j.bpj.2024.05.007 (2024)
- Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes Bradfield, JP; Kember, RL; Ulrich, A et al. Genome Biol, DOI://10.1186/s13059-023-03136-z (2024)
- Approximating facial expression effects on diagnostic accuracy via generative AI in medical genetics Patel, T; Othman, AA; Sümer, Ö et al. Bioinformatics, DOI://10.1093/bioinformatics/btae239 (2024)
- Dynamic Elevation of Aromatic Amino Acids in Hepatitis C Virus-Induced Cirrhosis After a Standard Meal Hill, KL; Haddad, JA; Ali, RO et al. Clin Transl Gastroenterol, DOI://10.14309/ctg.0000000000000666 (2024)
- A Comparison of CT-Based Pancreatic Segmentation Deep Learning Models Suri, A; Mukherjee, P; Pickhardt, PJ; Summers, RM; , Acad Radiol, DOI://10.1016/j.acra.2024.06.015 (2024)
- Hub stability in the calcium calmodulin-dependent protein kinase II Chien, CT; Puhl, H; Vogel, SS et al. Commun Biol, DOI://10.1038/s42003-024-06423-y (2024)
- A Camelid-Derived STAT-Specific Nanobody Inhibits Neuroinflammation and Ameliorates Experimental Autoimmune Encephalomyelitis (EAE) Mbanefo, EC; Seifert, A; Yadav, MK et al. Cells, DOI://10.3390/cells13121042 (2024)
- Most Fanconi anemia heterozygotes are not at increased cancer risk: A genome-first DiscovEHR cohort population study Deng, J; Altintas, B; Haley, JS et al. Genet Med, DOI://10.1016/j.gim.2023.101042 (2024)
- An Integrative Transcriptome Subtraction Strategy to Identify Human lncRNAs That Specifically Play a Role in Activation of Human Hepatic Stellate Cells Ma, Y; Harris, J; Li, P et al. Noncoding RNA, DOI://10.3390/ncrna10030034 (2024)
- Diversity, origin, and evolution of the ESCRT systems Makarova, KS; Tobiasson, V; Wolf, YI et al. mBio, DOI://10.1128/mbio.00335-24 (2024)
- CAR-T cell expansion platforms yield distinct T cell differentiation states Song, HW; Prochazkova, M; Shao, L et al. Cytotherapy, DOI://10.1016/j.jcyt.2024.03.003 (2024)
- Three-dimensional chromatin reorganization regulates B cell development during ageing Ma, F; Cao, Y; Du, H et al. Nat Cell Biol, DOI://10.1038/s41556-024-01424-9 (2024)
- A replication-deficient gammaherpesvirus vaccine protects mice from lytic disease and reduces latency establishment Bland, WA; Mitra, D; Owens, S et al. NPJ Vaccines, DOI://10.1038/s41541-024-00908-x (2024)
- The Structural Basis of the Activity Cliff in Modafinil-Based Dopamine Transporter Inhibitors Lee, KH; Camacho-Hernandez, GA; Newman, AH; Shi, L; , Biomolecules, DOI://10.3390/biom14060713 (2024)
- Perfluorinated Iridium Catalyst for Signal Amplification by Reversible Exchange Provides Metal-Free Aqueous Hyperpolarized [1-13C]-Pyruvate Ettedgui, J; Blackman, B; Raju, N et al. J Am Chem Soc, DOI://10.1021/jacs.3c11499 (2024)
- PERCEPTION predicts patient response and resistance to treatment using single-cell transcriptomics of their tumors Sinha, S; Vegesna, R; Mukherjee, S et al. Nat Cancer, DOI://10.1038/s43018-024-00756-7 (2024)
- Evaluation of somatic copy number variation detection by NGS technologies and bioinformatics tools on a hyper-diploid cancer genome Masood, D; Ren, L; Nguyen, C et al. Genome Biol, DOI://10.1186/s13059-024-03294-8 (2024)
- Canine meningiomas are comprised of 3 DNA methylation groups that resemble the molecular characteristics of human meningiomas Zakimi, N; Mazcko, CN; Toedebusch, C et al. Acta Neuropathol, DOI://10.1007/s00401-024-02693-2 (2024)
- Competitive Microarray Screening Reveals Functional Ligands for the DHX15 RNA G-Quadruplex Prestwood, PR; Yang, M; Lewis, GV et al. ACS Med Chem Lett, DOI://10.1021/acsmedchemlett.3c00574 (2024)
- Long noncoding RNA GATA2AS influences human erythropoiesis by transcription factor and chromatin landscape modulation Liu, G; Kim, J; Nguyen, N et al. Blood, DOI://10.1182/blood.2023021287 (2024)
- Comparative analysis and classification of highly divergent mouse rDNA units based on their intergenic spacer (IGS) variability Kim, JH; Nagaraja, R; Ogurtsov, AY et al. NAR Genom Bioinform, DOI://10.1093/nargab/lqae070 (2024)
- Effects of Xylanase A double mutation on substrate specificity and structural dynamics MacDonald, ME; Wells, NGM; Hassan, BA et al. J Struct Biol, DOI://10.1016/j.jsb.2024.108082 (2024)
- Genomic characterization of cervical lymph node metastases in papillary thyroid carcinoma following the Chornobyl accident Morton, LM; Lee, OW; Karyadi, DM et al. Nat Commun, DOI://10.1038/s41467-024-49292-z (2024)
- ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers Zhang, Y; Xie, G; Lee, JE et al. Nat Commun, DOI://10.1038/s41467-024-49391-x (2024)
- Stem cell dynamics and cellular heterogeneity across lineage subtypes of castrate-resistant prostate cancer Beshiri, ML; Capaldo, BJ; Lake, R et al. Stem Cells, DOI://10.1093/stmcls/sxae025 (2024)
- Linearly Amplified Single-Stranded RNA-Derived Transcriptome Sequencing (LAST-seq) Lyu, J; Chen, C; , Bio Protoc, DOI://10.21769/BioProtoc.4998 (2024)
- Anti-idiotype isolation of a broad and potent influenza A virus-neutralizing human antibody Olia, AS; Prabhakaran, M; Harris, DR et al. Front Immunol, DOI://10.3389/fimmu.2024.1399960 (2024)
- Protective human monoclonal antibodies target conserved sites of vulnerability on the underside of influenza virus neuraminidase Lederhofer, J; Tsybovsky, Y; Nguyen, L et al. Immunity, DOI://10.1016/j.immuni.2024.02.003 (2024)
- Racial Differences in Donor-Derived Cell-Free DNA and Mitochondrial DNA After Heart Transplantation, on Behalf of the GRAfT Investigators Shah, P; Agbor-Enoh, S; Lee, S et al. Circ Heart Fail, DOI://10.1161/CIRCHEARTFAILURE.123.011160 (2024)
- Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells Bu, W; Kumar, A; Board, NL et al. Immunity, DOI://10.1016/j.immuni.2024.02.008 (2024)
- Hemophagocytic Lymphohistiocytosis Gene Variants in Severe Aplastic Anemia and Their Impact on Hematopoietic Cell Transplantation Outcomes Rafati, M; McReynolds, LJ; Wang, Y et al. Transplant Cell Ther, DOI://10.1016/j.jtct.2024.05.017 (2024)
- KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma Kim, YY; Gryder, BE; Sinniah, R et al. Nat Commun, DOI://10.1038/s41467-024-45902-y (2024)
- Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas Choi, J; Ceribelli, M; Phelan, JD et al. Cancer Cell, DOI://10.1016/j.ccell.2024.04.007 (2024)
- Differentiating neural sensitivity and bias during face-emotion processing in youth: a computational approach Haller, SP; Stoddard, J; Cardenas, SI et al. Soc Cogn Affect Neurosci, DOI://10.1093/scan/nsae034 (2024)
- The complete sequence and comparative analysis of ape sex chromosomes Makova, KD; Pickett, BD; Harris, RS et al. Nature, DOI://10.1038/s41586-024-07473-2 (2024)
- De novo TLK1 and MDM1 mutations in a patient with a neurodevelopmental disorder and immunodeficiency Villamor-Payà, M; Sanchiz-Calvo, M; Smak, J et al. iScience, DOI://10.1016/j.isci.2024.109984 (2024)
- Sarcoma_CellminerCDB: A tool to interrogate the genomic and functional characteristics of a comprehensive collection of sarcoma cell lines Tlemsani, C; Heske, CM; Elloumi, F et al. iScience, DOI://10.1016/j.isci.2024.109781 (2024)
- Messenger RNA transport on lysosomal vesicles maintains axonal mitochondrial homeostasis and prevents axonal degeneration De Pace, R; Ghosh, S; Ryan, VH et al. Nat Neurosci, DOI://10.1038/s41593-024-01619-1 (2024)
- Systematic Assessment of Deep Learning-Based Predictors of Fragmentation Intensity Profiles Hamaneh, MB; Ogurtsov, AY; Obolensky, OI; Yu, YK; , J Proteome Res, DOI://10.1021/acs.jproteome.3c00857 (2024)
- DNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of histone supply chains Balachandra, V; Shrestha, RL; Hammond, CM et al. EMBO J, DOI://10.1038/s44318-024-00093-6 (2024)
- Catalytic residues of microRNA Argonautes play a modest role in microRNA star strand destabilization in C. elegans Kotagama, K; Grimme, AL; Braviner, L et al. Nucleic Acids Res, DOI://10.1093/nar/gkae170 (2024)
- Germline findings in cancer predisposing genes from a small cohort of chordoma patients Raygada, M; John, L; Liu, A et al. J Cancer Res Clin Oncol, DOI://10.1007/s00432-024-05706-5 (2024)
- hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50 Osei-Amponsa, V; Chandravanshi, M; Lu, X et al. Mol Cell, DOI://10.1016/j.molcel.2023.11.035 (2024)
- Multiplexing the Identification of Microorganisms via Tandem Mass Tag Labeling Augmented by Interference Removal through a Novel Modification of the Expectation Maximization Algorithm Alves, G; Ogurtsov, AY; Porterfield, H et al. J Am Soc Mass Spectrom, DOI://10.1021/jasms.3c00445 (2024)
- Spatial proximity of tumor-immune interactions predicts patient outcome in hepatocellular carcinoma Maestri, E; Kedei, N; Khatib, S et al. Hepatology, DOI://10.1097/HEP.0000000000000600 (2024)
- Adding Fuel to the Fire? The Skin Microbiome in Atopic Dermatitis Saheb Kashaf, S; Kong, HH; , J Invest Dermatol, DOI://10.1016/j.jid.2024.01.011 (2024)
- Abrogation of the G2/M checkpoint as a chemosensitization approach for alkylating agents Lang, F; Cornwell, JA; Kaur, K et al. Neuro Oncol, DOI://10.1093/neuonc/noad252 (2024)
- Sleep and Risk of Pancreatic Cancer in the UK Biobank Freeman, JR; Saint-Maurice, PF; Zhang, T et al. Cancer Epidemiol Biomarkers Prev, DOI://10.1158/1055-9965.EPI-23-0983 (2024)
- Decoupling the correlation between cytotoxic and exhausted T lymphocyte states enhances melanoma immunotherapy response prediction Wang, B; Wang, K; Wu, D et al. iScience, DOI://10.1016/j.isci.2024.109926 (2024)
- Automated detection of incidental abdominal aortic aneurysms on computed tomography Chatterjee, D; Shen, TC; Mukherjee, P et al. Abdom Radiol (NY), DOI://10.1007/s00261-023-04119-1 (2024)
- Acute depletion of BRG1 reveals its primary function as an activator of transcription Ren, G; Ku, WL; Ge, G et al. Nat Commun, DOI://10.1038/s41467-024-48911-z (2024)
- SHP2-EGFR States in Dephosphorylation Can Inform Selective SHP2 Inhibitors, Dampening RasGAP Action Liu, Y; Jang, H; Nussinov, R; , J Phys Chem B, DOI://10.1021/acs.jpcb.4c00873 (2024)
- Exploring the transcriptome of immature stages of Ornithodoros hermsi, the soft-tick vector of tick-borne relapsing fever de Sousa-Paula, LC; Berger, M; Talyuli, OAC et al. Sci Rep, DOI://10.1038/s41598-024-62732-6 (2024)
- Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate Zhan, J; Zeher, A; Huang, R et al. Nat Commun, DOI://10.1038/s41467-024-49029-y (2024)
- Exome sequencing implicates ancestry-related Mendelian variation at SYNE1 in childhood-onset essential hypertension Copeland, I; Wonkam-Tingang, E; Gupta-Malhotra, M et al. JCI Insight, DOI://10.1172/jci.insight.172152 (2024)
- Neoantigen-specific stimulation of tumor-infiltrating lymphocytes enables effective TCR isolation and expansion while preserving stem-like memory phenotypes Levin, N; Kim, SP; Marquardt, CA et al. J Immunother Cancer, DOI://10.1136/jitc-2023-008645 (2024)
- LORIS robustly predicts patient outcomes with immune checkpoint blockade therapy using common clinical, pathologic and genomic features Chang, TG; Cao, Y; Sfreddo, HJ et al. Nat Cancer, DOI://10.1038/s43018-024-00772-7 (2024)
- Biomimetic Vesicles with Designer Phospholipids Can Sense Environmental Redox Cues Erguven, H; Wang, L; Gutierrez, B et al. JACS Au, DOI://10.1021/jacsau.4c00041 (2024)
- CDK2 and CDK4: Cell Cycle Functions Evolve Distinct, Catalysis-Competent Conformations, Offering Drug Targets Zhang, W; Liu, Y; Jang, H; Nussinov, R; , JACS Au, DOI://10.1021/jacsau.4c00138 (2024)
- GPCR Screening Reveals that the Metabolite Receptor HCAR3 Regulates Epithelial Proliferation, Migration, and Cellular Respiration Pedro, MP; Lund, K; Kang, SWS et al. J Invest Dermatol, DOI://10.1016/j.jid.2023.12.002 (2024)
- A molecular switch controls assembly of bacterial focal adhesions Attia, B; My, L; Castaing, JP et al. Sci Adv, DOI://10.1126/sciadv.adn2789 (2024)
- Mechanism of complement inhibition by a mosquito protein revealed through cryo-EM Andersen, JF; Lei, H; Strayer, EC et al. Commun Biol, DOI://10.1038/s42003-024-06351-x (2024)
- Pathogenic CANVAS (AAGGG)n repeats stall DNA replication due to the formation of alternative DNA structures Hisey, JA; Radchenko, EA; Mandel, NH et al. Nucleic Acids Res, DOI://10.1093/nar/gkae124 (2024)
- Resf1 is a compound G4 quadruplex-associated tumor suppressor for triple negative breast cancer Majocha, MR; Jackson, DE; Ha, NH et al. PLoS Genet, DOI://10.1371/journal.pgen.1011236 (2024)
- The reference genome of Macropodus opercularis (the paradise fish) Fodor, E; Okendo, J; Szabó, N et al. Sci Data, DOI://10.1038/s41597-024-03277-1 (2024)
- Profiling complex repeat expansions in RFC1 in Parkinson's disease Alvarez Jerez, P; Daida, K; Miano-Burkhardt, A et al. NPJ Parkinsons Dis, DOI://10.1038/s41531-024-00723-0 (2024)
- Single-Shot 3D Reconstruction via Nonlinear Fringe Transformation: Supervised and Unsupervised Learning Approaches Nguyen, AH; Wang, Z; , Sensors (Basel), DOI://10.3390/s24103246 (2024)
- Dory: Computation of persistence diagrams up to dimension two for Vietoris-Rips filtrations of large data sets Aggarwal, M; Periwal, V; , J Comput Sci, DOI://10.1016/j.jocs.2024.102290 (2024)
- UPF1 ATPase autoinhibition and activation modulate RNA binding kinetics and NMD efficiency Chapman, JH; Youle, AM; Grimme, AL et al. Nucleic Acids Res, DOI://10.1093/nar/gkae136 (2024)
- Examining chromatin heterogeneity through PacBio long-read sequencing of M.EcoGII methylated genomes: an m6A detection efficiency and calling bias correcting pipeline Dennis, AF; Xu, Z; Clark, DJ; , Nucleic Acids Res, DOI://10.1093/nar/gkae288 (2024)
- Genome-wide analyses reveals an association between invasive urothelial carcinoma in the Shetland sheepdog and NIPAL1 Parker, HG; Harris, AC; Plassais, J et al. NPJ Precis Oncol, DOI://10.1038/s41698-024-00591-0 (2024)
- CoCoNuTs are a diverse subclass of Type IV restriction systems predicted to target RNA Bell, RT; Sahakyan, H; Makarova, KS et al. Elife, DOI://10.7554/eLife.94800 (2024)
- Identification of the potassium-binding site in serotonin transporter Hellsberg, E; Boytsov, D; Chen, Q et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2319384121 (2024)
- Germline pathogenic variants associated with triple-negative breast cancer in US Hispanic and Guatemalan women using hospital and community-based recruitment strategies Godinez Paredes, JM; Rodriguez, I; Ren, M et al. Breast Cancer Res Treat, DOI://10.1007/s10549-024-07300-2 (2024)
- Detection of abdominopelvic lymph nodes in multi-parametric MRI Mathai, TS; Shen, TC; Elton, DC et al. Comput Med Imaging Graph, DOI://10.1016/j.compmedimag.2024.102363 (2024)
- Segmentation of pelvic structures in T2 MRI via MR-to-CT synthesis Zhuang, Y; Mathai, TS; Mukherjee, P; Summers, RM; , Comput Med Imaging Graph, DOI://10.1016/j.compmedimag.2024.102335 (2024)
- MGMT ProFWise: Unlocking a New Application for Combined Feature Selection and the Rank-Based Weighting Method to Link MGMT Methylation Status to Serum Protein Expression in Patients with Glioblastoma Tasci, E; Shah, Y; Jagasia, S et al. Int J Mol Sci, DOI://10.3390/ijms25074082 (2024)
- Shared and distinct mechanisms of UBA1 inactivation across different diseases Collins, JC; Magaziner, SJ; English, M et al. EMBO J, DOI://10.1038/s44318-024-00046-z (2024)
- Correlation of protein binding pocket properties with hits' chemistries used in generation of ultra-large virtual libraries Song, RX; Nicklaus, MC; Tarasova, NI; , J Comput Aided Mol Des, DOI://10.1007/s10822-024-00562-4 (2024)
- Impacts of human mobility on the citywide transmission dynamics of 18 respiratory viruses in pre- and post-COVID-19 pandemic years Perofsky, AC; Hansen, CL; Burstein, R et al. Nat Commun, DOI://10.1038/s41467-024-48528-2 (2024)
- Regulation of T helper cell differentiation by the interplay between histone modification and chromatin interaction Liu, S; Cao, Y; Cui, K et al. Immunity, DOI://10.1016/j.immuni.2024.03.018 (2024)
- Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-Specific Transcriptome and Molecular Subtype Bahrambeigi, V; Lee, JJ; Branchi, V et al. Cancer Res, DOI://10.1158/0008-5472.CAN-23-4070 (2024)
- Structural Relationships to Efficacy for Prazole-Derived Antivirals Nyenhuis, DA; Watanabe, S; Bernstein, R et al. Adv Sci (Weinh), DOI://10.1002/advs.202308312 (2024)
- Fecal transplant from vaginally seeded infants decreases intraabdominal adiposity in mice Namasivayam, S; Tilves, C; Ding, H et al. Gut Microbes, DOI://10.1080/19490976.2024.2353394 (2024)
- Sex-difference in the association between social drinking, structural brain aging and cognitive function in older individuals free of cognitive impairment Abulseoud, OA; Caparelli, EC; Krell-Roesch, J et al. Front Psychiatry, DOI://10.3389/fpsyt.2024.1235171 (2024)
- The variation and evolution of complete human centromeres Logsdon, GA; Rozanski, AN; Ryabov, F et al. Nature, DOI://10.1038/s41586-024-07278-3 (2024)
- Defence systems and horizontal gene transfer in bacteria Kogay, R; Wolf, YI; Koonin, EV; , Environ Microbiol, DOI://10.1111/1462-2920.16630 (2024)
- Vitamin D regulates microbiome-dependent cancer immunity Giampazolias, E; Pereira da Costa, M; Lam, KC et al. Science, DOI://10.1126/science.adh7954 (2024)
- Programming a Ferroptosis-to-Apoptosis Transition Landscape Revealed Ferroptosis Biomarkers and Repressors for Cancer Therapy Vinik, Y; Maimon, A; Dubey, V et al. Adv Sci (Weinh), DOI://10.1002/advs.202307263 (2024)
- HPV oncogenes expressed from only one of multiple integrated HPV DNA copies drive clonal cell expansion in cervical cancer Yu, L; Majerciak, V; Lobanov, A et al. mBio, DOI://10.1128/mbio.00729-24 (2024)
- Functionally diverse thymic medullary epithelial cells interplay to direct central tolerance Ushio, A; Matsuda-Lennikov, M; Kalle-Youngoue, F et al. Cell Rep, DOI://10.1016/j.celrep.2024.114072 (2024)
- Magnolol derivatives as specific and noncytotoxic inhibitors of breast cancer resistance protein (BCRP/ABCG2) da Silva Zanzarini, I; Henrique Kita, D; Scheiffer, G et al. Bioorg Chem, DOI://10.1016/j.bioorg.2024.107283 (2024)
- Contrasting neurofunctional correlates of face- and visuospatial-processing in children and adolescents with Williams syndrome: convergent results from four fMRI paradigms Garvey, MH; Nash, T; Kippenhan, JS et al. Sci Rep, DOI://10.1038/s41598-024-60460-5 (2024)
- A Toxoplasma gondii O-glycosyltransferase that modulates bradyzoite cyst wall rigidity is distinct from host homologues Kumar, P; Tomita, T; Gerken, TA et al. Nat Commun, DOI://10.1038/s41467-024-48253-w (2024)
- Lessons learned from an fMRI-guided rTMS study on performance in a numerical Stroop task Beynel, L; Gura, H; Rezaee, Z et al. PLoS One, DOI://10.1371/journal.pone.0302660 (2024)
- Biallelic BORCS8 variants cause an infantile-onset neurodegenerative disorder with altered lysosome dynamics De Pace, R; Maroofian, R; Paimboeuf, A et al. Brain, DOI://10.1093/brain/awad427 (2024)
- An Ixodes persulcatus Inhibitor of Plasmin and Thrombin Hinders Keratinocyte Migration, Blood Coagulation, and Endothelial Permeability Berger, M; Rosa da Mata, S; Pizzolatti, NM et al. J Invest Dermatol, DOI://10.1016/j.jid.2023.10.026 (2024)
- Universal detection and segmentation of lymph nodes in multi-parametric MRI Mathai, TS; Lee, S; Shen, TC et al. Int J Comput Assist Radiol Surg, DOI://10.1007/s11548-023-02954-7 (2024)
- Protocol for the genomic analysis of salt-fractionated chromatin from frozen murine liver Yang, N; Sikder, S; Dalal, Y; Sen, P; , STAR Protoc, DOI://10.1016/j.xpro.2024.103043 (2024)
- Conformational free-energy landscapes of a Na+/Ca2+ exchanger explain its alternating-access mechanism and functional specificity Marinelli, F; Faraldo-Gómez, JD; , Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2318009121 (2024)
- Polycomb protein binding and looping in the ON transcriptional state Brown, JL; Zhang, L; Rocha, PP et al. Sci Adv, DOI://10.1126/sciadv.adn1837 (2024)
- The genome of the colonial hydroid Hydractinia reveals that their stem cells use a toolkit of evolutionarily shared genes with all animals Schnitzler, CE; Chang, ES; Waletich, J et al. Genome Res, DOI://10.1101/gr.278382.123 (2024)
- Network-based approach elucidates critical genes in BRCA subtypes and chemotherapy response in triple negative breast cancer Agrawal, P; Jain, N; Gopalan, V et al. iScience, DOI://10.1016/j.isci.2024.109752 (2024)
- Multi-omic profiling of follicular lymphoma reveals changes in tissue architecture and enhanced stromal remodeling in high-risk patients Radtke, AJ; Postovalova, E; Varlamova, A et al. Cancer Cell, DOI://10.1016/j.ccell.2024.02.001 (2024)
- Dopamine signaling enriched striatal gene set predicts striatal dopamine synthesis and physiological activity in vivo Sportelli, L; Eisenberg, DP; Passiatore, R et al. Nat Commun, DOI://10.1038/s41467-024-47456-5 (2024)
- Cortico-striatal differences in the epigenome in attention-deficit/ hyperactivity disorder Shastri, GG; Sudre, G; Ahn, K et al. Transl Psychiatry, DOI://10.1038/s41398-024-02896-x (2024)
- Large-scale genomic survey with deep learning-based method reveals strain-level phage specificity determinants Yang, Y; Dufault-Thompson, K; Yan, W et al. Gigascience, DOI://10.1093/gigascience/giae017 (2024)
- Altered pubertal timing in 7q11.23 copy number variations and associated genetic mechanisms Wei, SM; Gregory, MD; Nash, T et al. iScience, DOI://10.1016/j.isci.2024.109113 (2024)
- Cooperative Armoring of CAR and TCR T Cells by T Cell-Restricted IL15 and IL21 Universally Enhances Solid Tumor Efficacy Nguyen, R; Doubrovina, E; Mousset, CM et al. Clin Cancer Res, DOI://10.1158/1078-0432.CCR-23-1872 (2024)
- Immune determinants of CAR-T cell expansion in solid tumor patients receiving GD2 CAR-T cell therapy Kaczanowska, S; Murty, T; Alimadadi, A et al. Cancer Cell, DOI://10.1016/j.ccell.2023.11.011 (2024)
- A Unifying Model for Discordant and Concordant Results in Human Neuroimaging Studies of Facial Viewpoint Selectivity Revsine, C; Gonzalez-Castillo, J; Merriam, EP et al. J Neurosci, DOI://10.1523/JNEUROSCI.0296-23.2024 (2024)
- Lineage specific transcription factor waves reprogram neuroblastoma from self-renewal to differentiation Banerjee, D; Bagchi, S; Liu, Z et al. Nat Commun, DOI://10.1038/s41467-024-47166-y (2024)
- Light affects the prefrontal cortex via intrinsically photosensitive retinal ganglion cells Lazzerini Ospri, L; Zhan, JJ; Thomsen, MB et al. Sci Adv, DOI://10.1126/sciadv.adh9251 (2024)
- Estimating the overall fraction of phenotypic variance attributed to high-dimensional predictors measured with error Mandal, S; Kim, DH; Hua, X et al. Biostatistics, DOI://10.1093/biostatistics/kxad001 (2024)
- Revealing speckle obscured living human retinal cells with artificial intelligence assisted adaptive optics optical coherence tomography Das, V; Zhang, F; Bower, AJ et al. Commun Med (Lond), DOI://10.1038/s43856-024-00483-1 (2024)
- MUSSEL: Enhanced Bayesian polygenic risk prediction leveraging information across multiple ancestry groups Jin, J; Zhan, J; Zhang, J et al. Cell Genom, DOI://10.1016/j.xgen.2024.100539 (2024)
- rWTC-MBTA Vaccine Induces Potent Adaptive Immune Responses Against Glioblastomas via Dynamic Activation of Dendritic Cells Wang, H; Medina, R; Ye, J et al. Adv Sci (Weinh), DOI://10.1002/advs.202308280 (2024)
- Cell-type-specific mRNA transcription and degradation kinetics in zebrafish embryogenesis from metabolically labeled single-cell RNA-seq Fishman, L; Modak, A; Nechooshtan, G et al. Nat Commun, DOI://10.1038/s41467-024-47290-9 (2024)
- Homeodomain-only protein suppresses proliferation and contributes to differentiation- and age-related reduced CD8+ T cell expansion Yang, Q; Patrick, M; Lu, J et al. Front Immunol, DOI://10.3389/fimmu.2024.1360229 (2024)
- The small protein MntS evolved from a signal peptide and acquired a novel function regulating manganese homeostasis in Escherichia coli Wright, Z; Seymour, M; Paszczak, K et al. Mol Microbiol, DOI://10.1111/mmi.15206 (2024)
- Transcriptome-wide analysis of the function of Ded1 in translation preinitiation complex assembly in a reconstituted in vitro system Zhou, F; Bocetti, JM; Hou, M et al. Elife, DOI://10.7554/eLife.93255 (2024)
- Establishment and Characterization of Amitrole-Induced Mouse Thyroid Adenomatous Nodule-Derived Cell Lines Shirai, YT; Hoshi, N; Ward, JM et al. Thyroid, DOI://10.1089/thy.2023.0341 (2024)
- Inhibition of MEK Signaling Attenuates Cancer Stem Cell Activity in Anaplastic Thyroid Cancer Kimura, T; Doolittle, WKL; Kruhlak, M et al. Thyroid, DOI://10.1089/thy.2023.0521 (2024)
- Disruption of Ca2+/calmodulin:KSR1 interaction lowers ERK activation Thines, L; Jang, H; Li, Z et al. Protein Sci, DOI://10.1002/pro.4982 (2024)
- MYCN drives oncogenesis by cooperating with the histone methyltransferase G9a and the WDR5 adaptor to orchestrate global gene transcription Liu, Z; Zhang, X; Xu, M et al. PLoS Biol, DOI://10.1371/journal.pbio.3002240 (2024)
- Impact of CRISPR/HDR editing versus lentiviral transduction on long-term engraftment and clonal dynamics of HSPCs in rhesus macaques Lee, BC; Gin, A; Wu, C et al. Cell Stem Cell, DOI://10.1016/j.stem.2024.02.010 (2024)
- IKAROS gain of function disease: Allogeneic hematopoietic cell transplantation experience and expanded clinical phenotypes Klangkalya, N; Stoddard, J; Niemela, J et al. Clin Immunol, DOI://10.1016/j.clim.2024.109922 (2024)
- Point mutations in Arf1 reveal cooperative effects of the N-terminal extension and myristate for GTPase-activating protein catalytic activity Rosenberg, EM; Jian, X; Soubias, O et al. PLoS One, DOI://10.1371/journal.pone.0295103 (2024)
- Electric Field Characteristics of Rotating Permanent Magnet Stimulation Robins, PL; Makaroff, SN; Dib, M et al. Bioengineering (Basel), DOI://10.3390/bioengineering11030258 (2024)
- Clinical, behavioral, and electrophysiological profiles along a continuum of suicide risk: evidence from an implicit association task Lamontagne, SJ; Gilbert, JR; Zabala, PK et al. Psychol Med, DOI://10.1017/S0033291723003331 (2024)
- Conserved Noncoding Elements Evolve Around the Same Genes Throughout Metazoan Evolution Gonzalez, P; Hauck, QC; Baxevanis, AD; , Genome Biol Evol, DOI://10.1093/gbe/evae052 (2024)
- Questionnaire-based exposome-wide association studies for common diseases in the Personalized Environment and Genes Study Lloyd, D; House, JS; Akhtari, FS et al. Exposome, DOI://10.1093/exposome/osae002 (2024)
- Nucleosome reorganisation in breast cancer tissues Jacob, DR; Guiblet, WM; Mamayusupova, H et al. Clin Epigenetics, DOI://10.1186/s13148-024-01656-4 (2024)
- Flipped C-Terminal Ends of APOA1 Promote ABCA1-Dependent Cholesterol Efflux by Small HDLs He, Y; Pavanello, C; Hutchins, PM et al. Circulation, DOI://10.1161/CIRCULATIONAHA.123.065959 (2024)
- Cox model inference for relative hazard and pure risk from stratified weight-calibrated case-cohort data Etievant, L; Gail, MH; , Lifetime Data Anal, DOI://10.1007/s10985-024-09621-2 (2024)
- A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins Lu, X; Chandravanshi, M; Sabbasani, VR et al. Nat Commun, DOI://10.1038/s41467-024-46644-7 (2024)
- Syntaxin1A overexpression and pain insensitivity in individuals with 7q11.23 duplication syndrome Iadarola, MJ; Sapio, MR; Loydpierson, AJ et al. JCI Insight, DOI://10.1172/jci.insight.176147 (2024)
- Defining biology and recurrence risk in prostate cancers treated by neoadjuvant chemohormonal therapy Wilkinson, S; Sowalsky, AG; , J Natl Cancer Inst, DOI://10.1093/jnci/djad192 (2024)
- Corrigendum: Glioblastoma survival is associated with distinct proteomic alteration signatures post chemoirradiation in a large-scale proteomic panel Krauze, AV; Sierk, M; Nguyen, T et al. Front Oncol, DOI://10.3389/fonc.2024.1348105 (2024)
- Trial-by-trial variability in cortical responses exhibits scaling of spatial correlations predicted from critical dynamics Ribeiro, TL; Jendrichovsky, P; Yu, S et al. Cell Rep, DOI://10.1016/j.celrep.2024.113762 (2024)
- Outcome differences by sex in oncology clinical trials Kammula, AV; Schäffer, AA; Rajagopal, PS et al. Nat Commun, DOI://10.1038/s41467-024-46945-x (2024)
- Caspase-1 activates gasdermin A in non-mammals Billman, ZP; Kovacs, SB; Wei, B et al. Elife, DOI://10.7554/eLife.92362 (2024)
- Yeast eIF2A has a minimal role in translation initiation and uORF-mediated translational control in vivo Gaikwad, S; Ghobakhlou, F; Zhang, H; Hinnebusch, AG; , Elife, DOI://10.7554/eLife.92916 (2024)
- Transcriptional control of leukemogenesis by the chromatin reader SGF29 Barbosa, K; Deshpande, A; Perales, M et al. Blood, DOI://10.1182/blood.2023021234 (2024)
- AutoGVP: a dockerized workflow integrating ClinVar and InterVar germline sequence variant classification Kim, J; Naqvi, AS; Corbett, RJ et al. Bioinformatics, DOI://10.1093/bioinformatics/btae114 (2024)
- Recruitment and Maintenance of CX3CR1+CD4+ T Cells during Helminth Infection Loredan, DG; Devlin, JC; Khanna, KM; Loke, P; , J Immunol, DOI://10.4049/jimmunol.2300451 (2024)
- Comparative neuroimaging of sex differences in human and mouse brain anatomy Guma, E; Beauchamp, A; Liu, S et al. Elife, DOI://10.7554/eLife.92200 (2024)
- Leucine-rich repeat kinase 2 limits dopamine D1 receptor signaling in striatum and biases against heavy persistent alcohol drinking da Silva, D; Matsui, A; Murray, EM et al. Neuropsychopharmacology, DOI://10.1038/s41386-023-01731-z (2024)
- Annotating microbial functions with ProkFunFind Dufault-Thompson, K; Jiang, X; , mSystems, DOI://10.1128/msystems.00036-24 (2024)
- Molecular and clinicopathologic characteristics of CNS embryonal tumors with BRD4::LEUTX fusion Andreiuolo, F; Ferrone, CK; Rajan, S et al. Acta Neuropathol Commun, DOI://10.1186/s40478-024-01746-7 (2024)
- A longitudinal transcriptomic analysis of Rhipicephalus microplus midgut upon feeding Lu, S; Waldman, J; Parizi, LF et al. Ticks Tick Borne Dis, DOI://10.1016/j.ttbdis.2023.102304 (2024)
- Reprogramming of cardiac phosphoproteome, proteome, and transcriptome confers resilience to chronic adenylyl cyclase-driven stress Qu, JH; Chakir, K; Tarasov, KV et al. Elife, DOI://10.7554/eLife.88732 (2024)
- Degradation and translation of maternal mRNA for embryogenesis Yang, G; Xin, Q; Dean, J; , Trends Genet, DOI://10.1016/j.tig.2023.12.008 (2024)
- Comprehensive gene profiling of the metabolic landscape of humanized livers in mice Jiang, C; Li, P; Ma, Y et al. J Hepatol, DOI://10.1016/j.jhep.2023.11.020 (2024)
- Developmental conversion of thymocyte-attracting cells into self-antigen-displaying cells in embryonic thymus medulla epithelium Ohigashi, I; White, AJ; Yang, MT et al. Elife, DOI://10.7554/eLife.92552 (2024)
- QTL mapping of human retina DNA methylation identifies 87 gene-epigenome interactions in age-related macular degeneration Advani, J; Mehta, PA; Hamel, AR et al. Nat Commun, DOI://10.1038/s41467-024-46063-8 (2024)
- FRETpredict: a Python package for FRET efficiency predictions using rotamer libraries Montepietra, D; Tesei, G; Martins, JM et al. Commun Biol, DOI://10.1038/s42003-024-05910-6 (2024)
- Mycophenolate mofetil inhibits Merkel cell carcinoma growth Garman, KA; Thoreson, N; Strong, J et al. Br J Dermatol, DOI://10.1093/bjd/ljae018 (2024)
- Author Correction: ATR inhibition augments the efficacy of lurbinectedin in small-cell lung cancer Schultz, CW; Zhang, Y; Elmeskini, R et al. EMBO Mol Med, DOI://10.1038/s44321-024-00029-x (2024)
- Interferon induced circRNAs escape herpesvirus host shutoff and suppress lytic infection Dremel, SE; Tagawa, T; Koparde, VN et al. EMBO Rep, DOI://10.1038/s44319-023-00051-z (2024)
- Regional centromere configuration in the fungal pathogens of the Pneumocystis genus Cissé, OH; Curran, SJ; Folco, HD et al. mBio, DOI://10.1128/mbio.03185-23 (2024)
- Comparison of clinical geneticist and computer visual attention in assessing genetic conditions Duong, D; Johny, AR; Ledgister Hanchard, S et al. PLoS Genet, DOI://10.1371/journal.pgen.1011168 (2024)
- Complete genome sequence of a novel papillomavirus in Siamese fighting fish (Betta splendens) from Trinidad and Tobago Blake, L; Phillips Savage, AC; Soto, E et al. Microbiol Resour Announc, DOI://10.1128/mra.00999-23 (2024)
- Formation of Trideuteromethylated Artifacts of Pyrrole-Containing Natural Products Orfanoudaki, M; Akee, RK; Martínez-Fructuoso, L et al. J Nat Prod, DOI://10.1021/acs.jnatprod.3c01113 (2024)
- A spatial map of hepatic mitochondria uncovers functional heterogeneity shaped by nutrient-sensing signaling Kang, SWS; Cunningham, RP; Miller, CB et al. Nat Commun, DOI://10.1038/s41467-024-45751-9 (2024)
- Neopetrotaurines A-C, Isoquinoline Alkaloids with an Unprecedented Taurine Bridge from the Sponge Neopetrosia sp Wang, D; Jiang, W; Churiwal, M et al. J Nat Prod, DOI://10.1021/acs.jnatprod.3c01041 (2024)
- Tdrd3-null mice show post-transcriptional and behavioral impairments associated with neurogenesis and synaptic plasticity Zhu, X; Joo, Y; Bossi, S et al. Prog Neurobiol, DOI://10.1016/j.pneurobio.2024.102568 (2024)
- Biological aging markers in blood and brain tissue indicate age acceleration in alcohol use disorder Zillich, L; Cetin, M; Hummel, EM et al. Alcohol Clin Exp Res (Hoboken), DOI://10.1111/acer.15241 (2024)
- Gut-liver axis calibrates intestinal stem cell fitness Kim, G; Chen, Z; Li, J et al. Cell, DOI://10.1016/j.cell.2024.01.001 (2024)
- Actigraphy-derived measures of sleep and risk of prostate cancer in the UK Biobank Freeman, JR; Saint-Maurice, PF; Watts, EL et al. J Natl Cancer Inst, DOI://10.1093/jnci/djad210 (2024)
- Geographic Distribution of Human Infections with Zoonotic Ancylostoma ceylanicum and Anthropophilic Hookworms in Ecuador: A Retrospective Analysis of Archived Stool Samples Aguilar-Rodríguez, D; Seco-Hidalgo, V; Lopez, A et al. Am J Trop Med Hyg, DOI://10.4269/ajtmh.23-0469 (2024)
- Lineage and ecology define liver tumor evolution in response to treatment Revsine, M; Wang, L; Forgues, M et al. Cell Rep Med, DOI://10.1016/j.xcrm.2024.101394 (2024)
- Stromal Pbrm1 mediates chromatin remodeling necessary for embryo implantation in the mouse uterus Xin, Q; Feng, I; Yu, G; Dean, J; , J Clin Invest, DOI://10.1172/JCI174194 (2024)
- Combined immune checkpoint inhibition with durvalumab and tremelimumab with and without radiofrequency ablation in patients with advanced biliary tract carcinoma Monge, C; Xie, C; Myojin, Y et al. Cancer Med, DOI://10.1002/cam4.6912 (2024)
- Extrahelical Binding Site for a 1 H-Imidazo[4,5-c]quinolin-4-amine A3 Adenosine Receptor Positive Allosteric Modulator on Helix 8 and Distal Portions of Transmembrane Domains 1 and 7 Fisher, CL; Pavan, M; Salmaso, V et al. Mol Pharmacol, DOI://10.1124/molpharm.123.000784 (2024)
- Interactive data sharing for multiple questionnaire-based exposome-wide association studies and exposome correlations in the Personalized Environment and Genes Study Lloyd, D; House, JS; Akhtari, FS et al. Exposome, DOI://10.1093/exposome/osae003 (2024)
- The mineralocorticoid receptor forms higher order oligomers upon DNA binding Fettweis, G; Johnson, TA; Almeida-Prieto, B et al. Protein Sci, DOI://10.1002/pro.4890 (2024)
- Long-term survivors of glioblastoma: Tumor molecular, clinical, and imaging findings Briceno, N; Vera, E; Komlodi-Pasztor, E et al. Neurooncol Adv, DOI://10.1093/noajnl/vdae019 (2024)
- An unusual dual sugar-binding lectin domain controls the substrate specificity of a mucin-type O-glycosyltransferase Collette, AM; Hassan, SA; Schmidt, SI et al. Sci Adv, DOI://10.1126/sciadv.adj8829 (2024)
- Loss of Ezh2 in the medial ganglionic eminence alters interneuron fate, cell morphology and gene expression profiles Rhodes, CT; Asokumar, D; Sohn, M et al. Front Cell Neurosci, DOI://10.3389/fncel.2024.1334244 (2024)
- B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage Park, EN; Mackens-Kiani, T; Berhane, R et al. EMBO J, DOI://10.1038/s44318-023-00010-3 (2024)
- The cysteine-rich domain in CENP-A chaperone Scm3HJURP ensures centromere targeting and kinetochore integrity Folco, HD; Xiao, H; Wheeler, D et al. Nucleic Acids Res, DOI://10.1093/nar/gkad1182 (2024)
- Identification of two novel heterodimeric ABC transporters in melanoma: ABCB5β/B6 and ABCB5β/B9 Gerard, L; Duvivier, L; Fourrez, M et al. J Biol Chem, DOI://10.1016/j.jbc.2023.105594 (2024)
- ATOH1, TFAP2B, and CEACAM6 as Immunohistochemical Markers to Distinguish Merkel Cell Carcinoma and Small Cell Lung Cancer Vilasi, SM; Nguyen, J; Wang, CJ et al. Cancers (Basel), DOI://10.3390/cancers16040788 (2024)
- Lithium response in bipolar disorder is associated with focal adhesion and PI3K-Akt networks: a multi-omics replication study Ou, AH; Rosenthal, SB; Adli, M et al. Transl Psychiatry, DOI://10.1038/s41398-024-02811-4 (2024)
- Mitochondrial Cytochrome bc1 Complex as Validated Drug Target: A Structural Perspective Esser, L; Xia, D; , Trop Med Infect Dis, DOI://10.3390/tropicalmed9020039 (2024)
- Comparative evolution of influenza A virus H1 and H3 head and stalk domains across host species Trovão, NS; Khan, SM; Lemey, P et al. mBio, DOI://10.1128/mbio.02649-23 (2024)
- Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome Walitt, B; Singh, K; LaMunion, SR et al. Nat Commun, DOI://10.1038/s41467-024-45107-3 (2024)
- Genetic analysis of the X chromosome in people with Lewy body dementia nominates new risk loci Bayram, E; Reho, P; Litvan, I et al. NPJ Parkinsons Dis, DOI://10.1038/s41531-024-00649-7 (2024)
- EXO1 protects BRCA1-deficient cells against toxic DNA lesions van de Kooij, B; Schreuder, A; Pavani, R et al. Mol Cell, DOI://10.1016/j.molcel.2023.12.039 (2024)
- Multifaceted roles for STAT3 in gammaherpesvirus latency revealed through in vivo B cell knockout models Hogan, CH; Owens, SM; Reynoso, GV et al. mBio, DOI://10.1128/mbio.02998-23 (2024)
- Association of cardiovascular disease management drugs with Lewy body dementia: a case-control study Scholz, SW; Moroz, BE; Saez-Atienzar, S et al. Brain Commun, DOI://10.1093/braincomms/fcad346 (2024)
- Native FISH: A low- and high-throughput assay to analyze the alternative lengthening of telomere (ALT) pathway Azeroglu, B; Ozbun, L; Pegoraro, G; Lazzerini Denchi, E; , Methods Cell Biol, DOI://10.1016/bs.mcb.2022.10.010 (2024)
- Transgenic Tg(Kcnj10-ZsGreen) fluorescent reporter mice allow visualization of intermediate cells in the stria vascularis Strepay, D; Olszewski, RT; Nixon, S et al. Sci Rep, DOI://10.1038/s41598-024-52663-7 (2024)
- Trends in Patient Transfers From Overall and Caseload-Strained US Hospitals During the COVID-19 Pandemic Sarzynski, SH; Mancera, AG; Yek, C et al. JAMA Netw Open, DOI://10.1001/jamanetworkopen.2023.56174 (2024)
- The Variegation of Human Brain Vulnerability to Rare Genetic Disorders and Convergence With Behaviorally Defined Disorders Levitis, E; Liu, S; Whitman, ET et al. Biol Psychiatry, DOI://10.1016/j.biopsych.2023.07.008 (2024)
- Author Correction: Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex Hayne, CK; Butay, KJU; Stewart, ZD et al. Nat Struct Mol Biol, DOI://10.1038/s41594-024-01213-w (2024)
- A deep learning adversarial autoencoder with dynamic batching displays high performance in denoising and ordering scRNA-seq data Ko, KD; Sartorelli, V; , iScience, DOI://10.1016/j.isci.2024.109027 (2024)
- Diffuse Pediatric-type High-grade Glioma Arising in an Ovarian Mature Cystic Teratoma Elmuti, L; Amundson, J; Oberman, E et al. Int J Gynecol Pathol, DOI://10.1097/PGP.0000000000000954 (2024)
- Identification of Fibroinflammatory and Fibrotic Transcriptomic Subsets of Human Cutaneous Sclerotic Chronic Graft-Versus-Host Disease Rosenstein, RK; Rose, JJ; Brooks, SR et al. JID Innov, DOI://10.1016/j.xjidi.2023.100246 (2024)
- Computational analysis of genes with lethal knockout phenotype and prediction of essential genes in archaea Makarova, KS; Zhang, C; Wolf, YI et al. mBio, DOI://10.1128/mbio.03092-23 (2024)
- Rapid anti-myeloma activity by T cells expressing an anti-BCMA CAR with a human heavy-chain-only antigen-binding domain Mikkilineni, L; Natrakul, DA; Lam, N et al. Mol Ther, DOI://10.1016/j.ymthe.2023.12.018 (2024)
- Reappraisal of the DNA phosphorothioate modification machinery: uncovering neglected functional modalities and identification of new counter-invader defense systems Rakesh, S; Aravind, L; Krishnan, A; , Nucleic Acids Res, DOI://10.1093/nar/gkad1213 (2024)
- Observational and genetic associations between cardiorespiratory fitness and cancer: a UK Biobank and international consortia study Watts, EL; Gonzales, TI; Strain, T et al. Br J Cancer, DOI://10.1038/s41416-023-02489-3 (2024)
- Mapping the Oxygens in the Oxygen-Evolving Complex of Photosystem II by Their Nucleophilicity Using Quantum Descriptors Amin, M; Kaur, D; Brudvig, GW; Brooks, BR; , J Chem Theory Comput, DOI://10.1021/acs.jctc.3c00926 (2024)
- CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise Ma, J; Wang, PY; Zhuang, J et al. Cell Rep, DOI://10.1016/j.celrep.2023.113626 (2024)
- PancrESS - a meta-analysis resource for understanding cell-type specific expression in the human pancreas Sturgill, D; Wang, L; Arda, HE; , BMC Genomics, DOI://10.1186/s12864-024-09964-y (2024)
- Selective transcriptomic dysregulation of metabolic pathways in liver and retina by short- and long-term dietary hyperglycemia Mondal, AK; Brock, DC; Rowan, S et al. iScience, DOI://10.1016/j.isci.2024.108979 (2024)
- Rewiring of RNA methylation by the oncometabolite fumarate in renal cell carcinoma Fitzsimmons, CM; Mandler, MD; Lunger, JC et al. NAR Cancer, DOI://10.1093/narcan/zcae004 (2024)
- Variants in the WDR44 WD40-repeat domain cause a spectrum of ciliopathy by impairing ciliogenesis initiation Accogli, A; Shakya, S; Yang, T et al. Nat Commun, DOI://10.1038/s41467-023-44611-2 (2024)
- Multi-ancestry genome-wide association meta-analysis of Parkinson's disease Kim, JJ; Vitale, D; Otani, DV et al. Nat Genet, DOI://10.1038/s41588-023-01584-8 (2024)
- The allosteric mechanism of mTOR activation can inform bitopic inhibitor optimization Liu, Y; Zhang, M; Jang, H; Nussinov, R; , Chem Sci, DOI://10.1039/d3sc04690g (2024)
- Ongoing production of tissue-resident macrophages from hematopoietic stem cells in healthy adult macaques Rahmberg, AR; Wu, C; Shin, T et al. Blood Adv, DOI://10.1182/bloodadvances.2023011499 (2024)
- Genomic landscape of patients with germline RUNX1 variants and familial platelet disorder with myeloid malignancy Yu, K; Deuitch, N; Merguerian, M et al. Blood Adv, DOI://10.1182/bloodadvances.2023011165 (2024)
- Vasopressin V2 receptor, tolvaptan, and ERK1/2 phosphorylation in the renal collecting duct Khan, S; Raghuram, V; Chen, L et al. Am J Physiol Renal Physiol, DOI://10.1152/ajprenal.00124.2023 (2024)
- TGFβ prevents IgE-mediated allergic disease by restraining T follicular helper 2 differentiation Haque, TT; Weissler, KA; Schmiechen, Z et al. Sci Immunol, DOI://10.1126/sciimmunol.adg8691 (2024)
- Whole genome sequencing of 4,787 individuals identifies gene-based rare variants in age-related macular degeneration Kwong, A; Zawistowski, M; Fritsche, LG et al. Hum Mol Genet, DOI://10.1093/hmg/ddad189 (2024)
- Evaluation of a deuterated triarylmethyl spin probe for in vivo R2 ∗-based EPR oximetric imaging with enhanced dynamic range Kishimoto, S; Devasahayam, N; Chandramouli, GVR et al. Magn Reson Med, DOI://10.1002/mrm.29811 (2024)
- Changes in saliva protein profile throughout Rhipicephalus microplus blood feeding da Silva Vaz Junior, I; Lu, S; Pinto, AFM et al. Parasit Vectors, DOI://10.1186/s13071-024-06136-5 (2024)
- From the fat body to the hemolymph: Profiling tick immune and storage proteins through transcriptomics and proteomics Urbanová, V; Lu, S; Kalinová, E et al. Insect Biochem Mol Biol, DOI://10.1016/j.ibmb.2024.104072 (2024)
- BORIS/CTCFL epigenetically reprograms clustered CTCF binding sites into alternative transcriptional start sites Pugacheva, EM; Bhatt, DN; Rivero-Hinojosa, S et al. Genome Biol, DOI://10.1186/s13059-024-03175-0 (2024)
- omicSynth: An open multi-omic community resource for identifying druggable targets across neurodegenerative diseases Alvarado, CX; Makarious, MB; Weller, CA et al. Am J Hum Genet, DOI://10.1016/j.ajhg.2023.12.006 (2024)
- RNA-binding protein Nocte regulates Drosophila development by promoting translation reinitiation on mRNAs with long upstream open reading frames Zhang, T; Xue, Y; Su, S et al. Nucleic Acids Res, DOI://10.1093/nar/gkad1122 (2024)
- TGF-β and BMP signaling are associated with the transformation of glioblastoma to gliosarcoma and then osteosarcoma Li, A; Hancock, JC; Quezado, M et al. Neurooncol Adv, DOI://10.1093/noajnl/vdad164 (2024)
- Matrisome and Immune Pathways Contribute to Extreme Vascular Outcomes in Williams-Beuren Syndrome Liu, D; Billington, CJ; Raja, N et al. J Am Heart Assoc, DOI://10.1161/JAHA.123.031377 (2024)
- Towards a structural and functional analysis of the immunoglobulin-fold proteome Tawfeeq, C; Song, J; Khaniya, U et al. Adv Protein Chem Struct Biol, DOI://10.1016/bs.apcsb.2023.11.002 (2024)
- A systematic analysis of the landscape of synthetic lethality-driven precision oncology Schäffer, AA; Chung, Y; Kammula, AV et al. Med, DOI://10.1016/j.medj.2023.12.009 (2024)
- Inhibition of vertebrate complement system by hematophagous arthropods: inhibitory molecules, mechanisms, physiological roles, and applications Sant'Anna, MRV; Pereira-Filho, AA; Mendes-Sousa, AF et al. Insect Sci, DOI://10.1111/1744-7917.13317 (2024)
- Mock community taxonomic classification performance of publicly available shotgun metagenomics pipelines Valencia, EM; Maki, KA; Dootz, JN; Barb, JJ; , Sci Data, DOI://10.1038/s41597-023-02877-7 (2024)
- Ultra-rare genetic variation in relapsing polychondritis: a whole-exome sequencing study Luo, Y; Ferrada, MA; Sikora, KA et al. Ann Rheum Dis, DOI://10.1136/ard-2023-224732 (2024)
- GTax: improving de novo transcriptome assembly by removing foreign RNA contamination Alvarez, RV; Landsman, D; , Genome Biol, DOI://10.1186/s13059-023-03141-2 (2024)
- Analysis of rare Parkinson's disease variants in millions of people Pitz, V; Makarious, MB; Bandres-Ciga, S et al. NPJ Parkinsons Dis, DOI://10.1038/s41531-023-00608-8 (2024)
- BilR is a gut microbial enzyme that reduces bilirubin to urobilinogen Hall, B; Levy, S; Dufault-Thompson, K et al. Nat Microbiol, DOI://10.1038/s41564-023-01549-x (2024)
- Differential methylation analysis in neuropathologically confirmed dementia with Lewy bodies Reho, P; Saez-Atienzar, S; Ruffo, P et al. Commun Biol, DOI://10.1038/s42003-023-05725-x (2024)
- Human leukocyte antigen-DQA1*04:01 and rs2040406 variants are associated with elevated risk of childhood Burkitt lymphoma Liu, Z; Luo, Y; Kirimunda, S et al. Commun Biol, DOI://10.1038/s42003-023-05701-5 (2024)
- Cell-free DNA reveals distinct pathology of multisystem inflammatory syndrome in children Andargie, TE; Roznik, K; Redekar, N et al. J Clin Invest, DOI://10.1172/JCI178008 (2024)
- C-DARL: Contrastive diffusion adversarial representation learning for label-free blood vessel segmentation Kim, B; Oh, Y; Wood, BJ et al. Med Image Anal, DOI://10.1016/j.media.2023.103022 (2024)
- Brain Imaging and Registration in Larval Zebrafish Bhandiwad, AA; Gupta, T; Subedi, A et al. Methods Mol Biol, DOI://10.1007/978-1-0716-3401-1_9 (2024)
2023 (627 papers)
- Genome-Wide Meta-Analysis of Cerebrospinal Fluid Biomarkers in Alzheimer's Disease and Parkinson's Disease Cohorts Ta, M; Blauwendraat, C; Antar, T et al. Mov Disord, DOI://10.1002/mds.29511 (2023)
- Structural basis of microtubule depolymerization by the kinesin-like activity of HIV-1 Rev Eren, E; Watts, NR; Randazzo, D et al. Structure, DOI://10.1016/j.str.2023.07.009 (2023)
- Artificial Intelligence-Based PTEN Loss Assessment as an Early Predictor of Prostate Cancer Metastasis After Surgery: A Multicenter Retrospective Study Patel, P; Harmon, S; Iseman, R et al. Mod Pathol, DOI://10.1016/j.modpat.2023.100241 (2023)
- Feasibility of Using the Privacy-preserving Large Language Model Vicuna for Labeling Radiology Reports Mukherjee, P; Hou, B; Lanfredi, RB; Summers, RM; , Radiology, DOI://10.1148/radiol.231147 (2023)
- σ28-dependent small RNA regulation of flagella biosynthesis Melamed, S; Zhang, A; Jarnik, M et al. Elife, DOI://10.7554/eLife.87151 (2023)
- Elementary intracellular Ca signals approximated as a transition of release channel system from a metastable state Veron, G; Maltsev, VA; Stern, MD; Maltsev, AV; , J Appl Phys, DOI://10.1063/5.0151255 (2023)
- Direct observation of tRNA-chaperoned folding of a dynamic mRNA ensemble Suddala, KC; Yoo, J; Fan, L et al. Nat Commun, DOI://10.1038/s41467-023-41155-3 (2023)
- Serum biomarkers are altered in UK Biobank participants with mosaic chromosomal alterations Hubbard, AK; Brown, DW; Zhou, W et al. Hum Mol Genet, DOI://10.1093/hmg/ddad133 (2023)
- Selection and Interpretation of Molecular Diagnostics in Heart Transplantation Goldberg, JF; Truby, LK; Agbor-Enoh, S et al. Circulation, DOI://10.1161/CIRCULATIONAHA.123.062847 (2023)
- Cryptic splice mutation in the fumarate hydratase gene in patients with clinical manifestations of Hereditary Leiomyomatosis and Renal Cell Cancer Crooks, DR; Cawthon, GM; Fitzsimmons, CM et al. Hum Mol Genet, DOI://10.1093/hmg/ddad131 (2023)
- VirB, a key transcriptional regulator of Shigella virulence, requires a CTP ligand for its regulatory activities Gerson, TM; Ott, AM; Karney, MMA et al. mBio, DOI://10.1128/mbio.01519-23 (2023)
- Experimental bacterial dysbiosis with consequent immune alterations increase intrarectal SIV acquisition susceptibility Ortiz, AM; Baker, PJ; Langner, CA et al. Cell Rep, DOI://10.1016/j.celrep.2023.112020 (2023)
- Innate attraction and aversion to odors in locusts Ray, S; Sun, K; Stopfer, M; , PLoS One, DOI://10.1371/journal.pone.0284641 (2023)
- Dietary and supplemental intake of vitamins C and E is associated with altered DNA methylation in an epigenome-wide association study meta-analysis Keshawarz, A; Joehanes, R; Ma, J et al. Epigenetics, DOI://10.1080/15592294.2023.2211361 (2023)
- Quantitative flow cytometry enables end-to-end optimization of cross-platform extracellular vesicle studies Cook, S; Tang, VA; Lannigan, J et al. Cell Rep Methods, DOI://10.1016/j.crmeth.2023.100664 (2023)
- A fully automated FAIMS-DIA mass spectrometry-based proteomic pipeline Reilly, L; Lara, E; Ramos, D et al. Cell Rep Methods, DOI://10.1016/j.crmeth.2023.100593 (2023)
- The substrate and inhibitor binding mechanism of polyspecific transporter OAT1 revealed by high-resolution cryo-EM Dou, T; Lian, T; Shu, S et al. Nat Struct Mol Biol, DOI://10.1038/s41594-023-01123-3 (2023)
- Optimization of the Lead Compound NVP-BHG712 as a Colorectal Cancer Inhibitor Tröster, A; DiPrima, M; Jores, N et al. Chemistry, DOI://10.1002/chem.202203967 (2023)
- Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization Willems, SM; Ng, NHJ; Fernandez, J et al. Wellcome Open Res, DOI://10.12688/wellcomeopenres.18754.1 (2023)
- TScan-II: A genome-scale platform for the de novo identification of CD4+ T cell epitopes Dezfulian, MH; Kula, T; Pranzatelli, T et al. Cell, DOI://10.1016/j.cell.2023.10.024 (2023)
- Transcriptome-wide association study of circulating IgE levels identifies novel targets for asthma and allergic diseases Recto, KA; Huan, T; Lee, DH et al. Front Immunol, DOI://10.3389/fimmu.2023.1080071 (2023)
- Numbers and odds: TCR repertoire size and its age changes impacting on T cell functions Weng, NP Semin Immunol, DOI://10.1016/j.smim.2023.101810 (2023)
- TCF3 haploinsufficiency defined by immune, clinical, gene-dosage, and murine studies Boast, B; Goel, S; González-Granado, LI et al. J Allergy Clin Immunol, DOI://10.1016/j.jaci.2023.05.017 (2023)
- Nix interacts with WIPI2 to induce mitophagy Bunker, EN; Le Guerroué, F; Wang, C et al. EMBO J, DOI://10.15252/embj.2023113491 (2023)
- First Potent Macrocyclic A3 Adenosine Receptor Agonists Reveal G-Protein and β-Arrestin2 Signaling Preferences Tosh, DK; Fisher, CL; Salmaso, V et al. ACS Pharmacol Transl Sci, DOI://10.1021/acsptsci.3c00126 (2023)
- Neutrophil extracellular trap-associated carbamylation and histones trigger osteoclast formation in rheumatoid arthritis O'Neil, LJ; Oliveira, CB; Wang, X et al. Ann Rheum Dis, DOI://10.1136/ard-2022-223568 (2023)
- Obesity impacts the expression of Alzheimer's disease-related genes: The Framingham Heart Study Charisis, S; Lin, H; Ray, R et al. Alzheimers Dement, DOI://10.1002/alz.12954 (2023)
- Fully Automated Longitudinal Assessment of Renal Stone Burden on Serial CT Imaging Using Deep Learning Mukherjee, P; Lee, S; Elton, DC et al. J Endourol, DOI://10.1089/end.2023.0066 (2023)
- Transmission disequilibrium analysis of whole genome data in childhood-onset systemic lupus erythematosus Vazzana, KM; Musolf, AM; Bailey-Wilson, JE et al. Genes Immun, DOI://10.1038/s41435-023-00214-x (2023)
- Two complementary AI approaches for predicting UMLS semantic group assignment: heuristic reasoning and deep learning Mao, Y; Miller, RA; Bodenreider, O et al. J Am Med Inform Assoc, DOI://10.1093/jamia/ocad152 (2023)
- The tumor microenvironment state associates with response to HPV therapeutic vaccination in patients with respiratory papillomatosis Norberg, SM; Bai, K; Sievers, C et al. Sci Transl Med, DOI://10.1126/scitranslmed.adj0740 (2023)
- Combined inhibition of topoisomerase I and poly(ADP-ribose) polymerase: A synergistic therapeutic strategy for glioblastoma with phosphatase and tensin homolog deficiency Kim, O; Butler, M; Sergi, Z et al. Neurooncol Adv, DOI://10.1093/noajnl/vdad102 (2023)
- Epigenome-wide DNA methylation association study of circulating IgE levels identifies novel targets for asthma Recto, K; Kachroo, P; Huan, T et al. EBioMedicine, DOI://10.1016/j.ebiom.2023.104758 (2023)
- Human endogenous retrovirus K contributes to a stem cell niche in glioblastoma Shah, AH; Rivas, SR; Doucet-O'Hare, TT et al. J Clin Invest, DOI://10.1172/JCI167929 (2023)
- Monocyte-derived macrophages orchestrate multiple cell-type interactions to repair necrotic liver lesions in disease models Feng, D; Xiang, X; Guan, Y et al. J Clin Invest, DOI://10.1172/JCI166954 (2023)
- Crystal structure of Escherichia coli thiamine pyrophosphate-sensing riboswitch in the apo state Lee, HK; Lee, YT; Fan, L et al. Structure, DOI://10.1016/j.str.2023.05.003 (2023)
- Scalable Nanopore sequencing of human genomes provides a comprehensive view of haplotype-resolved variation and methylation Kolmogorov, M; Billingsley, KJ; Mastoras, M et al. Nat Methods, DOI://10.1038/s41592-023-01993-x (2023)
- Robust regulation of transcription pausing in Escherichia coli by the ubiquitous elongation factor NusG Yakhnin, AV; Bubunenko, M; Mandell, ZF et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2221114120 (2023)
- Examining the role of dopamine in methylphenidate's effects on resting brain function Tomasi, D; Manza, P; Yan, W et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2314596120 (2023)
- Single-cell analysis of shared signatures and transcriptional diversity during zebrafish development Sur, A; Wang, Y; Capar, P et al. Dev Cell, DOI://10.1016/j.devcel.2023.11.001 (2023)
- Secretoglobin 3A2 protects lung from developing cigarette smoke-induced pulmonary emphysema Kurotani, R; Ono, S; Miyano, Y et al. Int J Biochem Cell Biol, DOI://10.1016/j.biocel.2023.106390 (2023)
- Mosaic chromosomal alterations in peripheral blood leukocytes of children in sub-Saharan Africa Zhou, W; Fischer, A; Ogwang, MD et al. Nat Commun, DOI://10.1038/s41467-023-43881-0 (2023)
- Inhibition of NAD+-Dependent Metabolic Processes Induces Cellular Necrosis and Tumor Regression in Rhabdomyosarcoma Models McKay-Corkum, GB; Collins, VJ; Yeung, C et al. Clin Cancer Res, DOI://10.1158/1078-0432.CCR-23-0200 (2023)
- Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases Du, L; Wilson, BAP; Li, N et al. J Nat Prod, DOI://10.1021/acs.jnatprod.3c00394 (2023)
- Longitudinal Natural History Study of Children and Adults with Rare Solid Tumors: Initial Results for First 200 Participants Ahmed, S; Wedekind, MF; Del Rivero, J et al. Cancer Res Commun, DOI://10.1158/2767-9764.CRC-23-0247 (2023)
- A novel GATA2 distal enhancer mutation results in MonoMAC syndrome in 2 second cousins West, RR; Bauer, TR; Tuschong, LM et al. Blood Adv, DOI://10.1182/bloodadvances.2023010458 (2023)
- Cancer and Autism: How PTEN Mutations Degrade Function at the Membrane and Isoform Expression in the Human Brain Jang, H; Chen, J; Iakoucheva, LM; Nussinov, R; , J Mol Biol, DOI://10.1016/j.jmb.2023.168354 (2023)
- Purine anabolism creates therapeutic vulnerability in hepatocellular carcinoma through m 6 A-mediated epitranscriptomic regulation Hung, MH; Chang, CW; Wang, KC et al. Hepatology, DOI://10.1097/HEP.0000000000000420 (2023)
- "Online survey of COVID-19 immunization and infection in patients with systemic juvenile idiopathic arthritis and adult-onset still's disease." Marques, MC; Paul, S; Lake, C et al. Pediatr Rheumatol Online J, DOI://10.1186/s12969-023-00911-x (2023)
- Glucose-6-Phosphate Dehydrogenase Deficiency and Coronavirus Disease 2019 Israel, A; Berkovitch, M; Merzon, E et al. Clin Infect Dis, DOI://10.1093/cid/ciad348 (2023)
- Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response Pagadala, M; Sears, TJ; Wu, VH et al. Nat Commun, DOI://10.1038/s41467-023-38271-5 (2023)
- Evaluating the transcriptional landscape and cell-cell communication networks in chronically irradiated parotid glands Rheinheimer, BA; Pasquale, MC; , et al. iScience, DOI://10.1016/j.isci.2023.106660 (2023)
- An acetyltranferase moonlights as a regulator of the RNA binding repertoire of the RNA chaperone Hfq in Escherichia coli Luo, X; Zhang, A; Tai, CH et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2311509120 (2023)
- Microbiota configuration determines nutritional immune optimization Han, SJ; Stacy, A; Corral, D et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2304905120 (2023)
- Myr-Arf1 conformational flexibility at the membrane surface sheds light on the interactions with ArfGAP ASAP1 Zhang, Y; Soubias, O; Pant, S et al. Nat Commun, DOI://10.1038/s41467-023-43008-5 (2023)
- Multimodal spatiotemporal transcriptomic resolution of embryonic palate osteogenesis Piña, JO; Raju, R; Roth, DM et al. Nat Commun, DOI://10.1038/s41467-023-41349-9 (2023)
- Matrin3 regulates mitotic spindle dynamics by controlling alternative splicing of CDC14B Muys, BR; Shrestha, RL; Anastasakis, DG et al. Cell Rep, DOI://10.1016/j.celrep.2023.112260 (2023)
- An Overview of CD133 as a Functional Unit of Prognosis and Treatment Resistance in Glioblastoma Joyce, T; Jagasia, S; Tasci, E et al. Curr Oncol, DOI://10.3390/curroncol30090601 (2023)
- MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57Kip2 targeting Pomella, S; Cassandri, M; D'Archivio, L et al. Nat Commun, DOI://10.1038/s41467-023-44130-0 (2023)
- SHP2 clinical phenotype, cancer, or RASopathies, can be predicted by mutant conformational propensities Liu, Y; Zhang, W; Jang, H; Nussinov, R; , Cell Mol Life Sci, DOI://10.1007/s00018-023-05052-8 (2023)
- Dimerization mechanism of an inverted-topology ion channel in membranes Ernst, M; Orabi, EA; Stockbridge, RB et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2308454120 (2023)
- Integrated genomic and functional analyses of human skin-associated Staphylococcus reveal extensive inter- and intra-species diversity Joglekar, P; Conlan, S; Lee-Lin, SQ et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2310585120 (2023)
- Modeling islet enhancers using deep learning identifies candidate causal variants at loci associated with T2D and glycemic traits Hudaiberdiev, S; Taylor, DL; Song, W et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2206612120 (2023)
- Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma Tian, M; Wei, JS; Shivaprasad, N et al. Cell Rep Med, DOI://10.1016/j.xcrm.2023.101212 (2023)
- Distinct use of super-enhancer elements controls cell type-specific CD25 transcription and function Spolski, R; Li, P; Chandra, V et al. Sci Immunol, DOI://10.1126/sciimmunol.adi8217 (2023)
- Polygenic Parkinson's Disease Genetic Risk Score as Risk Modifier of Parkinsonism in Gaucher Disease Blauwendraat, C; Tayebi, N; Woo, EG et al. Mov Disord, DOI://10.1002/mds.29342 (2023)
- Atypical neurofibromatous lesions: Epigenetic cousins of other benign peripheral nerve sheath tumors? Ida, CM; Aldape, K; , Neuro Oncol, DOI://10.1093/neuonc/noad083 (2023)
- HECT domain interaction with ubiquitin binding sites on Tsg101-UEV controls HIV-1 egress, maturation, and infectivity Nyenhuis, DA; Rajasekaran, R; Watanabe, S et al. J Biol Chem, DOI://10.1016/j.jbc.2023.102901 (2023)
- A genetic basis of mitochondrial DNAJA3 in nonalcoholic steatohepatitis-related hepatocellular carcinoma Chang, CW; Chen, YS; Huang, CH et al. Hepatology, DOI://10.1097/HEP.0000000000000637 (2023)
- A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency , ; Fornes, O; Jia, A et al. Sci Immunol, DOI://10.1126/sciimmunol.ade7953 (2023)
- Quantitative mapping of the in vivo O-GalNAc glycoproteome in mouse tissues identifies GalNAc-T2 O-glycosites in metabolic disorder Yang, W; Tian, E; Chernish, A et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2303703120 (2023)
- ZFTA-fused supratentorial ependymoma with a novel fusion partner, DUX4 Gubbiotti, MA; Madsen, PJ; Tucker, AM et al. J Neuropathol Exp Neurol, DOI://10.1093/jnen/nlad038 (2023)
- Virus exposure and neurodegenerative disease risk across national biobanks Levine, KS; Leonard, HL; Blauwendraat, C et al. Neuron, DOI://10.1016/j.neuron.2022.12.029 (2023)
- Dynamic extracellular vestibule of human SERT: Unveiling druggable potential with high-affinity allosteric inhibitors Salomon, K; Abramyan, AM; Plenge, P et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2304089120 (2023)
- AGO2 silences mobile transposons in the nucleus of quiescent cells Sala, L; Kumar, M; Prajapat, M et al. Nat Struct Mol Biol, DOI://10.1038/s41594-023-01151-z (2023)
- A new method for multiancestry polygenic prediction improves performance across diverse populations Zhang, H; Zhan, J; Jin, J et al. Nat Genet, DOI://10.1038/s41588-023-01501-z (2023)
- Comprehensive mapping of cell fates in microsatellite unstable cancer cells supports dual targeting of WRN and ATR Zong, D; Koussa, NC; Cornwell, JA et al. Genes Dev, DOI://10.1101/gad.351085.123 (2023)
- Tick innate immune responses to hematophagy and Ehrlichia infection at single-cell resolution Adegoke, A; Ribeiro, JMC; Smith, RC; Karim, S; , Front Immunol, DOI://10.3389/fimmu.2023.1305976 (2023)
- Natural history study of patients with familial platelet disorder with associated myeloid malignancy Cunningham, L; Merguerian, M; Calvo, KR et al. Blood, DOI://10.1182/blood.2023019746 (2023)
- New biochemistry in the Rhodanese-phosphatase superfamily: emerging roles in diverse metabolic processes, nucleic acid modifications, and biological conflicts Burroughs, AM; Aravind, L; , NAR Genom Bioinform, DOI://10.1093/nargab/lqad029 (2023)
- Divergent HLA variations and heterogeneous expression but recurrent HLA loss-of- heterozygosity and common HLA-B and TAP transcriptional silencing across advanced pediatric solid cancers Lim, WC; Marques Da Costa, ME; Godefroy, K et al. Front Immunol, DOI://10.3389/fimmu.2023.1265469 (2023)
- Temporal continuity shapes visual responses of macaque face patch neurons Russ, BE; Koyano, KW; Day-Cooney, J et al. Neuron, DOI://10.1016/j.neuron.2022.12.021 (2023)
- Typed Markers and Context for Clinical Temporal Relation Extraction Cheng, C; Weiss, JC; , Proc Mach Learn Res, 2640-3498 (2023)
- Phenotypic signatures of circulating neoantigen-reactive CD8+ T cells in patients with metastatic cancers Yossef, R; Krishna, S; Sindiri, S et al. Cancer Cell, DOI://10.1016/j.ccell.2023.11.005 (2023)
- Integrative Mendelian randomization reveals the soluble receptor for advanced glycation end products as protective in relation to rheumatoid arthritis Lee, GY; Yao, C; Hwang, SJ et al. Sci Rep, DOI://10.1038/s41598-023-35098-4 (2023)
- Monitoring response to a clinically relevant IDH inhibitor in glioma-Hyperpolarized 13C magnetic resonance spectroscopy approaches Hong, D; Kim, Y; Mushti, C et al. Neurooncol Adv, DOI://10.1093/noajnl/vdad143 (2023)
- A draft of the genome of the Gulf Coast tick, Amblyomma maculatum Ribeiro, JMC; Bayona-Vásquez, NJ; Budachetri, K et al. Ticks Tick Borne Dis, DOI://10.1016/j.ttbdis.2022.102090 (2023)
- Myo-differentiation reporter screen reveals NF-Y as an activator of PAX3-FOXO1 in rhabdomyosarcoma Sroka, MW; Skopelitis, D; Vermunt, MW et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2303859120 (2023)
- ATR inhibition augments the efficacy of lurbinectedin in small-cell lung cancer Schultz, CW; Zhang, Y; Elmeskini, R et al. EMBO Mol Med, DOI://10.15252/emmm.202217313 (2023)
- Biosynthesis of glucocorticoids in tumors. Reply Taves, MD; Otsuka, S; Ashwell, JD; , J Clin Invest, DOI://10.1172/JCI175274 (2023)
- Tumor-derived biomarkers predict efficacy of B7H3 antibody-drug conjugate treatment in metastatic prostate cancer models Agarwal, S; Fang, L; McGowen, K et al. J Clin Invest, DOI://10.1172/JCI162148 (2023)
- Spatiotemporal Alterations in Working Memory-Related Beta Band Neuromagnetic Activity of Patients With Schizophrenia On and Off Antipsychotic Medication: Investigation With MEG Rubinstein, DY; Eisenberg, DP; Carver, FW et al. Schizophr Bull, DOI://10.1093/schbul/sbac178 (2023)
- Transcriptional profiling of canine osteosarcoma identifies prognostic gene expression signatures with translational value for humans Mannheimer, JD; Tawa, G; Gerhold, D et al. Commun Biol, DOI://10.1038/s42003-023-05208-z (2023)
- Pan-viral serology uncovers distinct virome patterns as risk predictors of hepatocellular carcinoma and intrahepatic cholangiocarcinoma Do, WL; Wang, L; Forgues, M et al. Cell Rep Med, DOI://10.1016/j.xcrm.2023.101328 (2023)
- Revisiting Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients with Glioblastoma-Proteomic Alteration and Comparison Analysis with the Standard-of-Care Chemoirradiation Krauze, AV; Zhao, Y; Li, MC et al. Biomolecules, DOI://10.3390/biom13101499 (2023)
- Population-specific Mutation Patterns in Breast Tumors from African American, European American, and Kenyan Patients Tang, W; Zhang, F; Byun, JS et al. Cancer Res Commun, DOI://10.1158/2767-9764.CRC-23-0165 (2023)
- Extracellular Vesicle Refractive Index Derivation Utilizing Orthogonal Characterization Pleet, ML; Cook, S; Tang, VA et al. Nano Lett, DOI://10.1021/acs.nanolett.3c00562 (2023)
- Specific inhibition of an anticancer target, polo-like kinase 1, by allosterically dismantling its mechanism of substrate recognition Park, JE; Kirsch, K; Lee, H et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2305037120 (2023)
- Diabetes-associated breast cancer is molecularly distinct and shows a DNA damage repair deficiency Panigrahi, G; Candia, J; Dorsey, TH et al. JCI Insight, DOI://10.1172/jci.insight.170105 (2023)
- Multi-omic network analysis identified betacellulin as a novel target of omega-3 fatty acid attenuation of western diet-induced nonalcoholic steatohepatitis Padiadpu, J; Garcia-Jaramillo, M; Newman, NK et al. EMBO Mol Med, DOI://10.15252/emmm.202318367 (2023)
- Increased interleukin-6/C-reactive protein levels are associated with the upregulation of the adenosine pathway and serve as potential markers of therapeutic resistance to immune checkpoint inhibitor-based therapies in non-small cell lung cancer Naqash, AR; McCallen, JD; Mi, E et al. J Immunother Cancer, DOI://10.1136/jitc-2023-007310 (2023)
- Piperacetazine Directly Binds to the PAX3::FOXO1 Fusion Protein and Inhibits Its Transcriptional Activity Nakazawa, K; Shaw, T; Song, YK et al. Cancer Res Commun, DOI://10.1158/2767-9764.CRC-23-0119 (2023)
- Expression of the transcription factor Klf6 by thymic epithelial cells is required for thymus development Malin, J; Martinez-Ruiz, GU; Zhao, Y et al. Sci Adv, DOI://10.1126/sciadv.adg8126 (2023)
- Expanding PROTACtable genome universe of E3 ligases Liu, Y; Yang, J; Wang, T et al. Nat Commun, DOI://10.1038/s41467-023-42233-2 (2023)
- Multi-ancestry meta-analysis and fine-mapping in Alzheimer's disease Lake, J; Warly Solsberg, C; Kim, JJ et al. Mol Psychiatry, DOI://10.1038/s41380-023-02089-w (2023)
- Can incorporating genotyping data into efficacy estimators improve efficiency of early phase malaria vaccine trials? Potter, GE; Callier, V; Shrestha, B et al. Malar J, DOI://10.1186/s12936-023-04802-0 (2023)
- Early short-term effects on catecholamine levels and pituitary function in patients with pheochromocytoma or paraganglioma treated with [177Lu]Lu-DOTA-TATE therapy Gubbi, S; Al-Jundi, M; Auh, S et al. Front Endocrinol (Lausanne), DOI://10.3389/fendo.2023.1275813 (2023)
- Elevated A-to-I RNA editing in COVID-19 infected individuals Merdler-Rabinowicz, R; Gorelik, D; Park, J et al. NAR Genom Bioinform, DOI://10.1093/nargab/lqad092 (2023)
- 2-Amino-5-arylethynyl-thiophen-3-yl-(phenyl)methanones as A1 Adenosine Receptor Positive Allosteric Modulators Oliva, P; Suresh, RR; Pasquini, S et al. ACS Med Chem Lett, DOI://10.1021/acsmedchemlett.3c00315 (2023)
- Targeting TREM1 augments antitumor T cell immunity by inhibiting myeloid-derived suppressor cells and restraining anti-PD-1 resistance Ajith, A; Mamouni, K; Horuzsko, DD et al. J Clin Invest, DOI://10.1172/JCI167951 (2023)
- Phase I trial of Ganitumab plus Dasatinib to Cotarget the Insulin-Like Growth Factor 1 Receptor and Src Family Kinase YES in Rhabdomyosarcoma Akshintala, S; Sundby, RT; Bernstein, D et al. Clin Cancer Res, DOI://10.1158/1078-0432.CCR-23-0709 (2023)
- Molecular Graph-Based Deep Learning Algorithm Facilitates an Imaging-Based Strategy for Rapid Discovery of Small Molecules Modulating Biomolecular Condensates Gao, P; Zhang, Q; Keely, D et al. J Med Chem, DOI://10.1021/acs.jmedchem.3c00490 (2023)
- Patterns of metastatic progression and association with clinical outcomes in canine osteosarcoma: A necropsy study of 83 dogs Silver, KI; Patkar, S; Mazcko, C et al. Vet Comp Oncol, DOI://10.1111/vco.12927 (2023)
- The association between inflammatory bowel disease and all-cause and cause-specific mortality in the UK Biobank Li, F; Ramirez, Y; Yano, Y et al. Ann Epidemiol, DOI://10.1016/j.annepidem.2023.10.008 (2023)
- Second-site suppressor mutations reveal connection between the drug-binding pocket and nucleotide-binding domain 1 of human P-glycoprotein (ABCB1) Murakami, M; Sajid, A; Lusvarghi, S et al. Drug Resist Updat, DOI://10.1016/j.drup.2023.101009 (2023)
- GradWise: A Novel Application of a Rank-Based Weighted Hybrid Filter and Embedded Feature Selection Method for Glioma Grading with Clinical and Molecular Characteristics Tasci, E; Jagasia, S; Zhuge, Y et al. Cancers (Basel), DOI://10.3390/cancers15184628 (2023)
- Profiles of Wnt pathway gene expression during tooth morphogenesis Raju, R; Piña, JO; Roth, DM et al. Front Physiol, DOI://10.3389/fphys.2023.1316635 (2023)
- Spatial Mechano-Signaling Regulation of GTPases through Non-Degradative Ubiquitination Sewduth, RN; Carai, P; Ivanisevic, T et al. Adv Sci (Weinh), DOI://10.1002/advs.202303367 (2023)
- JAK2 V617F mutation and associated chromosomal alterations in primary and secondary myelofibrosis and post-HCT outcomes Rafati, M; Brown, DW; Zhou, W et al. Blood Adv, DOI://10.1182/bloodadvances.2023010882 (2023)
- Single-cell RNA sequencing reveals cancer stem-like cells and dynamics in tumor microenvironment during cholangiocarcinoma progression Golino, JL; Bian, J; Wang, X et al. Front Cell Dev Biol, DOI://10.3389/fcell.2023.1250215 (2023)
- Molecular mechanism of EAG1 channel inhibition by imipramine binding to the PAS domain Wang, ZJ; Ghorbani, M; Chen, X et al. J Biol Chem, DOI://10.1016/j.jbc.2023.105391 (2023)
- PET-measured human dopamine synthesis capacity and receptor availability predict trading rewards and time-costs during foraging Ianni, AM; Eisenberg, DP; Boorman, ED et al. Nat Commun, DOI://10.1038/s41467-023-41897-0 (2023)
- Rickettsial Infection in Ticks from a National Park in the Cerrado Biome, Midwestern Brazil Paludo, RLDR; Paula, WVF; Neves, LC et al. Pathogens, DOI://10.3390/pathogens13010013 (2023)
- Non-selective dampening of the host immune response after hepatitis C clearance and its association with circulating chemokine and endotoxin levels Quinn, G; Ali, RO; Zhang, GY et al. Liver Int, DOI://10.1111/liv.15737 (2023)
- Genome-wide profiling of transcription factor activity in primary liver cancer using single-cell ATAC sequencing Craig, AJ; Silveira, MAD; Ma, L et al. Cell Rep, DOI://10.1016/j.celrep.2023.113446 (2023)
- Stage-specific dynamic reorganization of genome topology shapes transcriptional neighborhoods in developing human retinal organoids Qu, Z; Batz, Z; Singh, N et al. Cell Rep, DOI://10.1016/j.celrep.2023.113543 (2023)
- The complete sequence of a human Y chromosome Rhie, A; Nurk, S; Cechova, M et al. Nature, DOI://10.1038/s41586-023-06457-y (2023)
- Instance segmentation of mitochondria in electron microscopy images with a generalist deep learning model trained on a diverse dataset Conrad, R; Narayan, K; , Cell Syst, DOI://10.1016/j.cels.2022.12.006 (2023)
- Genomic characterization of the C. tuberculostearicum species complex, a prominent member of the human skin microbiome Ahmed, N; Joglekar, P; Deming, C et al. mSystems, DOI://10.1128/msystems.00632-23 (2023)
- Caregivers Attitude Detection From Clinical Notes Manzo, G; Celi, LA; Shabazz, Y et al. AMIA Annu Symp Proc, 1942-597X (2023)
- Effects of Porting Essie Tokenization and Normalization to Solr Gayen, S; Gupta, D; F Loane, R et al. AMIA Annu Symp Proc, 1942-597X (2023)
- Oncolytic adenoviruses expressing checkpoint inhibitors for cancer therapy Xie, D; Tian, Y; Hu, D et al. Signal Transduct Target Ther, DOI://10.1038/s41392-023-01683-2 (2023)
- Bitter- and Umami-Related Genes are Differentially Associated with Food Group Intakes: the Framingham Heart Study Gervis, JE; Ma, J; Chui, KKH et al. J Nutr, DOI://10.1016/j.tjnut.2022.11.005 (2023)
- Tumor eradication by hetIL-15 locoregional therapy correlates with an induced intratumoral CD103intCD11b+ dendritic cell population Stellas, D; Karaliota, S; Stravokefalou, V et al. Cell Rep, DOI://10.1016/j.celrep.2023.112501 (2023)
- Polymorphism in the ZNF804A Gene and Variation in D1 and D2/D3 Dopamine Receptor Availability in the Healthy Human Brain: A Dual Positron Emission Tomography Study Hegarty, CE; Ianni, AM; Kohn, PD et al. Biol Psychiatry Cogn Neurosci Neuroimaging, DOI://10.1016/j.bpsc.2020.12.006 (2023)
- Single-cell methylation sequencing data reveal succinct metastatic migration histories and tumor progression models Liu, Y; Li, XC; Rashidi Mehrabadi, F et al. Genome Res, DOI://10.1101/gr.277608.122 (2023)
- Observation of pH-Dependent Residual Structure in the Pmel17 Repeat Domain and the Implication for Its Amyloid Formation Morris, DL; Nyenhuis, DA; Dean, DN et al. Biochemistry, DOI://10.1021/acs.biochem.3c00445 (2023)
- A novel conceptual model of heart rate autonomic modulation based on a small-world modular structure of the sinoatrial node Maltsev, AV; Stern, MD; Lakatta, EG; Maltsev, VA; , Front Physiol, DOI://10.3389/fphys.2023.1276023 (2023)
- Diversity of short linear interaction motifs in SARS-CoV-2 nucleocapsid protein Schuck, P; Zhao, H; , mBio, DOI://10.1128/mbio.02388-23 (2023)
- Examination of newborn DNA methylation among women with polycystic ovary syndrome/hirsutism Polinski, KJ; Robinson, SL; Putnick, DL et al. Epigenetics, DOI://10.1080/15592294.2023.2282319 (2023)
- Changes in Behavior and Neural Dynamics across Adolescent Development Liuzzi, L; Pine, DS; Fox, NA; Averbeck, BB; , J Neurosci, DOI://10.1523/JNEUROSCI.0462-23.2023 (2023)
- Decoding complexity in biomolecular recognition of DNA i-motifs with microarrays Yazdani, K; Seshadri, S; Tillo, D et al. Nucleic Acids Res, DOI://10.1093/nar/gkad981 (2023)
- Acid phosphatase-like proteins, a biogenic amine and leukotriene-binding salivary protein family from the flea Xenopsylla cheopis Lu, S; Andersen, JF; Bosio, CF et al. Commun Biol, DOI://10.1038/s42003-023-05679-0 (2023)
- A resource of induced pluripotent stem cell (iPSC) lines including clinical, genomic, and cellular data from genetically isolated families with mood and psychotic disorders Detera-Wadleigh, SD; Kassem, L; Besancon, E et al. Transl Psychiatry, DOI://10.1038/s41398-023-02641-w (2023)
- Pseudo-Label Assisted nnU-Net enables automatic segmentation of 7T MRI from a single acquisition Donnay, C; Dieckhaus, H; Tsagkas, C et al. Front Neuroimaging, DOI://10.3389/fnimg.2023.1252261 (2023)
- Exploratory Studies of Effective Inhibitors against the SARS-CoV-2 Main Protease by Halogen Incorporation and Amide Bond Replacement Tsuji, K; Kobayakawa, T; Ishii, T et al. Chem Pharm Bull (Tokyo), DOI://10.1248/cpb.c23-00562 (2023)
- Functional Pdgfra fibroblast heterogeneity in normal and fibrotic mouse lung Trempus, CS; Papas, BN; Sifre, MI et al. JCI Insight, DOI://10.1172/jci.insight.164380 (2023)
- ApoER2-Dab1 disruption as the origin of pTau-associated neurodegeneration in sporadic Alzheimer's disease Ramsden, CE; Zamora, D; Horowitz, MS et al. Acta Neuropathol Commun, DOI://10.1186/s40478-023-01693-9 (2023)
- Ubiquitin Ligases Siah1a/2 Control Alveolar Macrophage Functions to Limit Carcinogen-Induced Lung Adenocarcinoma Scortegagna, M; Du, Y; Bradley, LM et al. Cancer Res, DOI://10.1158/0008-5472.CAN-23-0258 (2023)
- Eukaryotic Kv channel Shaker inactivates through selectivity filter dilation rather than collapse Stix, R; Tan, XF; Bae, C et al. Sci Adv, DOI://10.1126/sciadv.adj5539 (2023)
- PCSK9, A Promising Novel Target for Age-Related Cardiovascular Dysfunction Matyas, C; Trojnar, E; Zhao, S et al. JACC Basic Transl Sci, DOI://10.1016/j.jacbts.2023.06.005 (2023)
- Dermis resident macrophages orchestrate localized ILC2 eosinophil circuitries to promote non-healing cutaneous leishmaniasis Lee, SH; Kang, B; Kamenyeva, O et al. Nat Commun, DOI://10.1038/s41467-023-43588-2 (2023)
- A deep learning segmentation method to assess dose to organs at risk during breast radiotherapy Saha, M; Jung, JW; Lee, SW et al. Phys Imaging Radiat Oncol, DOI://10.1016/j.phro.2023.100520 (2023)
- Mendelian randomization analyses suggest a causal role for circulating GIP and IL-1RA levels in homeostatic model assessment-derived measures of β-cell function and insulin sensitivity in Africans without type 2 diabetes Meeks, KAC; Bentley, AR; Assimes, TL et al. Genome Med, DOI://10.1186/s13073-023-01263-7 (2023)
- Dietary fish oil enriched in very-long-chain polyunsaturated fatty acid reduces cardiometabolic risk factors and improves retinal function Yang, ZH; Gorusupudi, A; Lydic, TA et al. iScience, DOI://10.1016/j.isci.2023.108411 (2023)
- Extrachromosomal Amplification of Human Papillomavirus Episomes Is a Mechanism of Cervical Carcinogenesis Rossi, NM; Dai, J; Xie, Y et al. Cancer Res, DOI://10.1158/0008-5472.CAN-22-3030 (2023)
- Reference on copy number variations in pleomorphic xanthoastrocytoma: Implications for diagnostic approach Reuss, DE; Schrimpf, D; Stichel, D et al. Free Neuropathol, DOI://10.17879/freeneuropathology-2023-5156 (2023)
- Functionally comparable but evolutionarily distinct nucleotide-targeting effectors help identify conserved paradigms across diverse immune systems Nicastro, GG; Burroughs, AM; Iyer, LM; Aravind, L; , Nucleic Acids Res, DOI://10.1093/nar/gkad879 (2023)
- Geometric and topological characterization of the cytoarchitecture of islets of Langerhans Aggarwal, M; Striegel, DA; Hara, M; Periwal, V; , PLoS Comput Biol, DOI://10.1371/journal.pcbi.1011617 (2023)
- SIRT1 Prevents R-Loops during Chronological Aging by Modulating DNA Replication at rDNA Loci Thakur, BL; Kusi, NA; Mosavarpour, S et al. Cells, DOI://10.3390/cells12222630 (2023)
- Discovery of a Novel Intron in US10/US11/US12 of HSV-1 Strain 17 Chang, W; Hao, M; Qiu, J et al. Viruses, DOI://10.3390/v15112144 (2023)
- Brief Report: The Virome of Bladder Tumors Arising in People Living With HIV Starrett, GJ; Foster, H; Sigel, K et al. J Acquir Immune Defic Syndr, DOI://10.1097/QAI.0000000000003283 (2023)
- Effects of stopping criterion on the growth of trees in regression random forests Arsham, A; Rosenberg, P; Little, M; , N Engl J Stat Data Sci, DOI://10.51387/22-nejsds5 (2023)
- Investigating the NRAS 5' UTR as a target for small molecules Balaratnam, S; Torrey, ZR; Calabrese, DR et al. Cell Chem Biol, DOI://10.1016/j.chembiol.2023.05.004 (2023)
- SARS-CoV-2 antibodies recognize 23 distinct epitopic sites on the receptor binding domain Jiang, J; Boughter, CT; Ahmad, J et al. Commun Biol, DOI://10.1038/s42003-023-05332-w (2023)
- In vivo deuterium magnetic resonance imaging of xenografted tumors following systemic administration of deuterated water Brender, JR; Assmann, JC; Farthing, DE et al. Sci Rep, DOI://10.1038/s41598-023-41163-9 (2023)
- Inherited ARPC5 mutations cause an actinopathy impairing cell motility and disrupting cytokine signaling Nunes-Santos, CJ; Kuehn, H; Boast, B et al. Nat Commun, DOI://10.1038/s41467-023-39272-0 (2023)
- Data-driven transcriptomics analysis identifies PCSK9 as a novel key regulator in liver aging Arif, M; Matyas, C; Mukhopadhyay, P et al. Geroscience, DOI://10.1007/s11357-023-00928-w (2023)
- Tumors produce glucocorticoids by metabolite recycling, not synthesis, and activate Tregs to promote growth Taves, MD; Otsuka, S; Taylor, MA et al. J Clin Invest, DOI://10.1172/JCI164599 (2023)
- Zfp281 and Zfp148 control CD4+ T cell thymic development and TH2 functions Chopp, LB; Zhu, X; Gao, Y et al. Sci Immunol, DOI://10.1126/sciimmunol.adi9066 (2023)
- Reduced female fertility due to sequestration of RNA Pol II by pervasive transcription in exosome RNase-depleted oocytes Wu, D; Dean, J; , Cell Rep, DOI://10.1016/j.celrep.2023.113247 (2023)
- Functional interrogation of twenty type 2 diabetes-associated genes using isogenic human embryonic stem cell-derived β-like cells Xue, D; Narisu, N; Taylor, DL et al. Cell Metab, DOI://10.1016/j.cmet.2023.09.013 (2023)
- Mapping the individual human cortex using multidimensional MRI and unsupervised learning Kundu, S; Barsoum, S; Ariza, J et al. Brain Commun, DOI://10.1093/braincomms/fcad258 (2023)
- A genome catalog of the early-life human skin microbiome Shen, Z; Robert, L; Stolpman, M et al. Genome Biol, DOI://10.1186/s13059-023-03090-w (2023)
- Somatic mutational landscape of hereditary hematopoietic malignancies caused by germline variants in RUNX1, GATA2, and DDX41 Homan, CC; Drazer, MW; Yu, K et al. Blood Adv, DOI://10.1182/bloodadvances.2023010045 (2023)
- Cryo-EM structures of human magnesium channel MRS2 reveal gating and regulatory mechanisms Lai, LTF; Balaraman, J; Zhou, F; Matthies, D; , Nat Commun, DOI://10.1038/s41467-023-42599-3 (2023)
- Unappreciated subcontinental admixture in Europeans and European Americans and implications for genetic epidemiology studies Gouveia, MH; Bentley, AR; Leal, TP et al. Nat Commun, DOI://10.1038/s41467-023-42491-0 (2023)
- Leishmania genetic exchange is mediated by IgM natural antibodies Serafim, TD; Iniguez, E; Barletta, ABF et al. Nature, DOI://10.1038/s41586-023-06655-8 (2023)
- Parasite Detection in Visceral Leishmaniasis Samples by Dye-Based qPCR Using New Gene Targets of Leishmania infantum and Crithidia Takamiya, NT; Rogerio, LA; Torres, C et al. Trop Med Infect Dis, DOI://10.3390/tropicalmed8080405 (2023)
- Subtle Structural Modification of a Synthetic Cannabinoid Receptor Agonist Drastically Increases its Efficacy at the CB1 Receptor Yano, H; Chitsazi, R; Lucaj, C et al. ACS Chem Neurosci, DOI://10.1021/acschemneuro.3c00530 (2023)
- Reappraisal of Idiopathic CD4 Lymphocytopenia at 30 Years Lisco, A; Ortega-Villa, AM; Mystakelis, H et al. N Engl J Med, DOI://10.1056/NEJMoa2202348 (2023)
- Transcriptome of Left Ventricle and Sinoatrial Node in Young and Old C57 Mice Qu, JH; Tarasov, KV; Tarasova, YS et al. Fortune J Health Sci, DOI://10.26502/fjhs.134 (2023)
- Highly complete long-read genomes reveal pangenomic variation underlying yeast phenotypic diversity Weller, CA; Andreev, I; Chambers, MJ et al. Genome Res, DOI://10.1101/gr.277515.122 (2023)
- Co-localization of clusters of TCR-regulated genes with TAD rearrangements Gao, GF; Li, P; Leonard, WJ; , BMC Genomics, DOI://10.1186/s12864-023-09693-8 (2023)
- Identification of a new polyomavirus in distinct human populations and tissues Torres, C; Correa, RM; Picconi, MA et al. J Med Virol, DOI://10.1002/jmv.29197 (2023)
- Advances in the structure, mechanism and targeting of chemoresistance-linked ABC transporters Sajid, A; Rahman, H; Ambudkar, SV; , Nat Rev Cancer, DOI://10.1038/s41568-023-00612-3 (2023)
- SARS-CoV-2 infection establishes a stable and age-independent CD8+ T ce Choy, C; Chen, J; Li, J et al. Nat Commun, DOI://10.1038/s41467-023-42430-z (2023)
- Expanded microbiome niches of RAG-deficient patients Blaustein, RA; Shen, Z; Kashaf, SS et al. Cell Rep Med, DOI://10.1016/j.xcrm.2023.101205 (2023)
- Mechanism and evolutionary origins of alanine-tail C-degron recognition by E3 ligases Pirh2 and CRL2-KLHDC10 Patil, PR; Burroughs, AM; Misra, M et al. Cell Rep, DOI://10.1016/j.celrep.2023.113100 (2023)
- Inactivation of the Kv2.1 channel through electromechanical coupling Fernández-Mariño, AI; Tan, XF; Bae, C et al. Nature, DOI://10.1038/s41586-023-06582-8 (2023)
- Predicting Molecular Subtype and Survival of Rhabdomyosarcoma Patients Using Deep Learning of H&E Images: A Report from the Children's Oncology Group Milewski, D; Jung, H; Brown, GT et al. Clin Cancer Res, DOI://10.1158/1078-0432.CCR-22-1663 (2023)
- Apoptosis-induced nuclear expulsion in tumor cells drives S100a4-mediated metastatic outgrowth through the RAGE pathway Park, WY; Gray, JM; Holewinski, RJ et al. Nat Cancer, DOI://10.1038/s43018-023-00524-z (2023)
- The multidrug resistance transporter P-glycoprotein confers resistance to ferroptosis inducers Frye, WJE; Huff, LM; González Dalmasy, JM et al. Cancer Drug Resist, DOI://10.20517/cdr.2023.29 (2023)
- PLAE Web App Enables Powerful Searching and Multiple Visualizations Across One Million Unified Single-Cell Ocular Transcriptomes Swamy, VS; Batz, ZA; McGaughey, DM; , Transl Vis Sci Technol, DOI://10.1167/tvst.12.9.18 (2023)
- Thyroid hormone receptor α1: a novel regulator of thyroid cancer cell differentiation Hwang, E; Doolittle, WKL; Zhu, YJ et al. Oncogene, DOI://10.1038/s41388-023-02815-2 (2023)
- Pan-Cancer Analysis of Patient Tumor Single-Cell Transcriptomes Identifies Promising Selective and Safe Chimeric Antigen Receptor Targets in Head and Neck Cancer Madan, S; Sinha, S; Chang, T et al. Cancers (Basel), DOI://10.3390/cancers15194885 (2023)
- Dysregulation of Mitochondrial Translation Caused by CBFB Deficiency Cooperates with Mutant PIK3CA and Is a Vulnerability in Breast Cancer Malik, N; Kim, YI; Yan, H et al. Cancer Res, DOI://10.1158/0008-5472.CAN-22-2525 (2023)
- Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM Ding, J; Deme, JC; Stagno, JR et al. Nucleic Acids Res, DOI://10.1093/nar/gkad651 (2023)
- Structure-Activity Relationship Studies of SARS-CoV-2 Main Protease Inhibitors Containing 4-Fluorobenzothiazole-2-carbonyl Moieties Tsuji, K; Ishii, T; Kobayakawa, T et al. J Med Chem, DOI://10.1021/acs.jmedchem.3c00777 (2023)
- Autolysosomal exocytosis of lipids protect neurons from ferroptosis Ralhan, I; Chang, J; Moulton, MJ et al. J Cell Biol, DOI://10.1083/jcb.202207130 (2023)
- Glucose-6-phosphate dehydrogenase deficiency and long-term risk of immune-related disorders Israel, A; Schäffer, AA; Berkovitch, M et al. Front Immunol, DOI://10.3389/fimmu.2023.1232560 (2023)
- Chromatin Accessibility Landscape of Human Triple-negative Breast Cancer Cell Lines Reveals Variation by Patient Donor Ancestry Harris, AR; Panigrahi, G; Liu, H et al. Cancer Res Commun, DOI://10.1158/2767-9764.CRC-23-0236 (2023)
- Diffusion tensor free water MRI predicts progression of FLAIR white matter hyperintensities after ischemic stroke Kern, KC; Zagzoug, MS; Gottesman, RF et al. Front Neurol, DOI://10.3389/fneur.2023.1172031 (2023)
- Synthesis and Antiphytopathogenic Activity of Novel Oxazolidine-2,4-diones Bearing Phenoxypyridine Moiety Liu, Y; Esser, L; Bai, H et al. J Agric Food Chem, DOI://10.1021/acs.jafc.3c03464 (2023)
- Protein Kinase B (PKB/AKT) Protects IDH-Mutated Glioma from Ferroptosis via Nrf2 Liu, Y; Chou, FJ; Lang, F et al. Clin Cancer Res, DOI://10.1158/1078-0432.CCR-22-3179 (2023)
- Medical Image Retrieval via Nearest Neighbor Search on Pre-trained Image Features Gupta, D; Loane, R; Gayen, S; Demner-Fushman, D; , Knowl Based Syst, DOI://10.1016/j.knosys.2023.110907 (2023)
- Identification of neoepitope reactive T-cell receptors guided by HLA-A*03:01 and HLA-A*11:01 immunopeptidomics Ade, CM; Sporn, MJ; Das, S et al. J Immunother Cancer, DOI://10.1136/jitc-2023-007097 (2023)
- REUSED: A deep neural network method for rapid whole-brain high-resolution myelin water fraction mapping from extremely under-sampled MRI Gong, Z; Khattar, N; Kiely, M et al. Comput Med Imaging Graph, DOI://10.1016/j.compmedimag.2023.102282 (2023)
- A planar polarized MYO6-DOCK7-RAC1 axis promotes tissue fluidification in mammary epithelia Menin, L; Weber, J; Villa, S et al. Cell Rep, DOI://10.1016/j.celrep.2023.113001 (2023)
- An Investigation of Structure-Activity Relationships and Cell Death Mechanisms of the Marine Alkaloids Discorhabdins in Merkel Cell Carcinoma Cells Orfanoudaki, M; Smith, EA; Hill, NT et al. Mar Drugs, DOI://10.3390/md21090474 (2023)
- Intensive systolic blood pressure treatment remodels brain perivascular spaces: A secondary analysis of the Systolic Pressure Intervention Trial (SPRINT) Kern, KC; Nasrallah, IM; Bryan, RN et al. Neuroimage Clin, DOI://10.1016/j.nicl.2023.103513 (2023)
- Genome-First Approach of the Prevalence and Cancer Phenotypes of Pathogenic or Likely Pathogenic Germline TP53 Variants de Andrade, KC; Strande, NT; Kim, J et al. HGG Adv, DOI://10.1016/j.xhgg.2023.100242 (2023)
- Cell-free chromatin immunoprecipitation to detect molecular pathways in heart transplantation Jang, MK; Markowitz, TE; Andargie, TE et al. Life Sci Alliance, DOI://10.26508/lsa.202302003 (2023)
- Hypertensive Adults Exhibit Lower Myelin Content: A Multicomponent Relaxometry and Diffusion Magnetic Resonance Imaging Study Laporte, JP; Faulkner, ME; Gong, Z et al. Hypertension, DOI://10.1161/HYPERTENSIONAHA.123.21012 (2023)
- Upregulation of Somatostatin Receptor Type 2 Improves 177Lu-DOTATATE Therapy in Receptor-Deficient Pancreatic Neuroendocrine Tumor Model Sharma, R; Earla, B; Baidoo, KE et al. Mol Cancer Ther, DOI://10.1158/1535-7163.MCT-22-0798 (2023)
- Transcriptional landscape of Kaposi sarcoma tumors identifies unique immunologic signatures and key determinants of angiogenesis Ramaswami, R; Tagawa, T; Mahesh, G et al. J Transl Med, DOI://10.1186/s12967-023-04517-5 (2023)
- A comprehensive analysis of adverse events in the first 30 days of phase 1 pediatric CAR T-cell trials Silbert, SK; Madan, S; Holland, EM et al. Blood Adv, DOI://10.1182/bloodadvances.2023009789 (2023)
- CHD7 variants associated with hearing loss and enlargement of the vestibular aqueduct Roux, I; Fenollar-Ferrer, C; Lee, HJ et al. Hum Genet, DOI://10.1007/s00439-023-02581-x (2023)
- Universal Genome-Wide Association Studies: Powerful Joint Ancestry and Association Testing Shriner, D; Bentley, AR; Gouveia, MH et al. HGG Adv, DOI://10.1016/j.xhgg.2023.100235 (2023)
- IFNL4 Genotypes and Risk of Childhood Burkitt Lymphoma in East Africa Baker, FS; Wang, J; Florez-Vargas, O et al. J Interferon Cytokine Res, DOI://10.1089/jir.2023.0014 (2023)
- HLA in isolated REM sleep behavior disorder and Lewy body dementia Yu, E; Krohn, L; Ruskey, JA et al. Ann Clin Transl Neurol, DOI://10.1002/acn3.51841 (2023)
- Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection West, EE; Merle, NS; Kamiński, MM et al. Immunity, DOI://10.1016/j.immuni.2023.07.014 (2023)
- Transcription factor EGR2 controls homing and pathogenicity of TH17 cells in the central nervous system Gao, Y; Wang, Y; Chauss, D et al. Nat Immunol, DOI://10.1038/s41590-023-01553-7 (2023)
- Chromatin remodeling of prostaglandin signaling in smooth muscle enables mouse embryo passage through the female reproductive tract Xin, Q; Yu, G; Feng, I; Dean, J; , Dev Cell, DOI://10.1016/j.devcel.2023.08.025 (2023)
- Comparative Evaluation of Current Biochemical-, Sequencing-, and Proteomic-Based Identification Methods for the Streptococcus bovis Group Putnam, NE; Youn, JH; Wallace, MA et al. J Clin Microbiol, DOI://10.1128/jcm.01712-22 (2023)
- An Artificial Intelligence Approach for Tackling Conformational Energy Uncertainties in Chiroptical Spectroscopies Marton, G; Koenis, MAJ; Liu, HB et al. Angew Chem Int Ed Engl, DOI://10.1002/anie.202307053 (2023)
- Cannabinoformins: Designing Biguanide-Embedded, Orally Available, Peripherally Selective Cannabinoid-1 Receptor Antagonists for Metabolic Syndrome Disorders Dvorácskó, S; Herrerias, A; Oliverio, A et al. J Med Chem, DOI://10.1021/acs.jmedchem.3c00599 (2023)
- TNFR1 and TNFR2, Which Link NF-κB Activation, Drive Lung Cancer Progression, Cell Dedifferentiation, and Metastasis Shi, G; Hu, Y; , Cancers (Basel), DOI://10.3390/cancers15174299 (2023)
- Using patient-derived tumor organoids from common epithelial cancers to analyze personalized T-cell responses to neoantigens Parikh, AY; Masi, R; Gasmi, B et al. Cancer Immunol Immunother, DOI://10.1007/s00262-023-03476-6 (2023)
- Designed nanoparticles elicit cross-reactive antibody responses to conserved influenza virus hemagglutinin stem epitopes McCraw, DM; Myers, ML; Gulati, NM et al. PLoS Pathog, DOI://10.1371/journal.ppat.1011514 (2023)
- HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide Wang, S; Matassoli, F; Zhang, B et al. Cell Rep, DOI://10.1016/j.celrep.2023.112755 (2023)
- Absence of TRIC-B from type XIV Osteogenesis Imperfecta osteoblasts alters cell adhesion and mitochondrial function - A multi-omics study Jovanovic, M; Mitra, A; Besio, R et al. Matrix Biol, DOI://10.1016/j.matbio.2023.06.004 (2023)
- Highly pathogenic avian influenza A (H5N1) in marine mammals and seabirds in Peru Leguia, M; Garcia-Glaessner, A; Muñoz-Saavedra, B et al. Nat Commun, DOI://10.1038/s41467-023-41182-0 (2023)
- Evaluating the Cysteine-Rich and Catalytic Subdomains of Human Tyrosinase and OCA1-Related Mutants Using 1 μs Molecular Dynamics Simulation Woods, T; Sergeev, YV; , Int J Mol Sci, DOI://10.3390/ijms241713032 (2023)
- Sarcopenia and gut microbiota alterations in patients with hematological diseases before and after hematopoietic stem cell transplantation Wang, B; Hu, W; Zhang, X et al. Chin J Cancer Res, DOI://10.21147/j.issn.1000-9604.2023.04.05 (2023)
- Accelerated evolution of SARS-CoV-2 in free-ranging white-tailed deer McBride, DS; Garushyants, SK; Franks, J et al. Nat Commun, DOI://10.1038/s41467-023-40706-y (2023)
- Evolutionary selection of proteins with two folds Schafer, JW; Porter, LL; , Nat Commun, DOI://10.1038/s41467-023-41237-2 (2023)
- A brain specific alternatively spliced isoform of nonmuscle myosin IIA lacks its mechanoenzymatic activities Das, S; Mallick, D; Sarkar, S et al. J Biol Chem, DOI://10.1016/j.jbc.2023.105143 (2023)
- Aire drives steroid hormone biosynthesis by medullary thymic epithelial cells Taves, MD; Donahue, KM; Bian, J et al. Sci Immunol, DOI://10.1126/sciimmunol.abo7975 (2023)
- Vaccine elicitation and structural basis for antibody protection against alphaviruses Sutton, MS; Pletnev, S; Callahan, V et al. Cell, DOI://10.1016/j.cell.2023.05.019 (2023)
- Opioid receptor antagonism and neural response to monetary rewards: Pilot studies in light and heavy alcohol users Gowin, JL; Sloan, ME; Kirk-Provencher, KT et al. J Psychopharmacol, DOI://10.1177/02698811231191707 (2023)
- Development of a bicistronic anti-CD19/CD20 CAR construct including abrogation of unexpected nucleic acid sequence deletions Lam, N; Finney, R; Yang, S et al. Mol Ther Oncolytics, DOI://10.1016/j.omto.2023.07.001 (2023)
- OPA1 helical structures give perspective to mitochondrial dysfunction Nyenhuis, SB; Wu, X; Strub, MP et al. Nature, DOI://10.1038/s41586-023-06462-1 (2023)
- The Molecular Mechanism of Positive Allosteric Modulation at the Dopamine D1 Receptor Goldberg, A; Xie, B; Shi, L; , Int J Mol Sci, DOI://10.3390/ijms241612848 (2023)
- Membrane free-energy landscapes derived from atomistic dynamics explain nonuniversal cholesterol-induced stiffening Fiorin, G; Forrest, LR; Faraldo-Gómez, JD; , PNAS Nexus, DOI://10.1093/pnasnexus/pgad269 (2023)
- Optimizing TMS Coil Placement Approaches for Targeting the Dorsolateral Prefrontal Cortex in Depressed Adolescents: An Electric Field Modeling Study Deng, ZD; Robins, PL; Dannhauer, M et al. Biomedicines, DOI://10.3390/biomedicines11082320 (2023)
- Intestinal microbiome and metabolome signatures in patients with chronic granulomatous disease Chandrasekaran, P; Han, Y; Zerbe, CS et al. J Allergy Clin Immunol, DOI://10.1016/j.jaci.2023.07.022 (2023)
- Macrophage-mediated extracellular matrix remodeling controls host Staphylococcus aureus susceptibility in the skin Voisin, B; Nadella, V; Doebel, T et al. Immunity, DOI://10.1016/j.immuni.2023.06.006 (2023)
- Genotype-Phenotype Association in ABCA4-Associated Retinopathy Pfau, M; Zein, WM; Huryn, LA et al. Adv Exp Med Biol, DOI://10.1007/978-3-031-27681-1_42 (2023)
- Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants Li, M; Oliveira Passos, D; Shan, Z et al. Sci Adv, DOI://10.1126/sciadv.adg5953 (2023)
- Dorsal visual stream and LIMK1: hemideletion, haplotype, and enduring effects in children with Williams syndrome Kippenhan, JS; Gregory, MD; Nash, T et al. J Neurodev Disord, DOI://10.1186/s11689-023-09493-x (2023)
- Time-Distributed Framework for 3D Reconstruction Integrating Fringe Projection with Deep Learning Nguyen, AH; Wang, Z; , Sensors (Basel), DOI://10.3390/s23167284 (2023)
- Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin Ruf, B; Bruhns, M; Babaei, S et al. Cell, DOI://10.1016/j.cell.2023.07.026 (2023)
- Optimizing treatment allocation in randomized clinical trials by leveraging baseline covariates Zhang, W; Zhang, Z; Liu, A; , Biometrics, DOI://10.1111/biom.13914 (2023)
- Germline Exome Sequencing for Men with Testicular Germ Cell Tumor Reveals Coding Defects in Chromosomal Segregation and Protein-targeting Genes Pyle, LC; Kim, J; Bradfield, J et al. Eur Urol, DOI://10.1016/j.eururo.2023.05.008 (2023)
- Design of cell-type-specific hyperstable IL-4 mimetics via modular de novo scaffolds Yang, H; Ulge, UY; Quijano-Rubio, A et al. Nat Chem Biol, DOI://10.1038/s41589-023-01313-6 (2023)
- Fluid protein fold space and its implications Porter, LL Bioessays, DOI://10.1002/bies.202300057 (2023)
- Evidence for virus-mediated oncogenesis in bladder cancers arising in solid organ transplant recipients Starrett, GJ; Yu, K; Golubeva, Y et al. Elife, DOI://10.7554/eLife.82690 (2023)
- Bacterial NLR-related proteins protect against phage Kibby, EM; Conte, AN; Burroughs, AM et al. Cell, DOI://10.1016/j.cell.2023.04.015 (2023)
- Nonlinear expression patterns and multiple shifts in gene network interactions underlie robust phenotypic change in Drosophila melanogaster selected for night sleep duration Souto-Maior, C; Serrano Negron, YL; Harbison, ST; , PLoS Comput Biol, DOI://10.1371/journal.pcbi.1011389 (2023)
- Characterization of leukemia progression in the Cbfb-MYH11 knockin mice by single cell RNA sequencing Diemer, JL; Yu, K; Kelly, M et al. Leukemia, DOI://10.1038/s41375-023-01926-9 (2023)
- B cell depletion therapy does not resolve chronic active multiple sclerosis lesions Maggi, P; Bulcke, CV; Pedrini, E et al. EBioMedicine, DOI://10.1016/j.ebiom.2023.104701 (2023)
- Cell-specific and shared regulatory elements control a multigene locus active in mammary and salivary glands Lee, HK; Willi, M; Liu, C; Hennighausen, L; , Nat Commun, DOI://10.1038/s41467-023-40712-0 (2023)
- Single-cell transcriptomic analysis of the identity and function of fibro/adipogenic progenitors in healthy and dystrophic muscle Uapinyoying, P; Hogarth, M; Battacharya, S et al. iScience, DOI://10.1016/j.isci.2023.107479 (2023)
- Identification of eight novel proteasome variants in five unrelated cases of proteasome-associated autoinflammatory syndromes (PRAAS) Papendorf, JJ; Ebstein, F; Alehashemi, S et al. Front Immunol, DOI://10.3389/fimmu.2023.1190104 (2023)
- Single-Cell Analysis of CX3CR1+ Cells Reveals a Pathogenic Role for BIRC5+ Myeloid Proliferating Cells Driven by Staphylococcus aureus Leukotoxins Loredan, DG; Devlin, JC; Lacey, KA et al. J Immunol, DOI://10.4049/jimmunol.2300166 (2023)
- A novel ARPKD mouse model with near-complete deletion of the Polycystic Kidney and Hepatic Disease 1 (Pkhd1) genomic locus presents with multiple phenotypes but not renal cysts Ishimoto, Y; Menezes, LF; Zhou, F et al. Kidney Int, DOI://10.1016/j.kint.2023.05.027 (2023)
- Pacak-Zhuang syndrome: a model providing new insights into tumor syndromes Rosenblum, JS; Wang, H; Nazari, MA et al. Endocr Relat Cancer, DOI://10.1530/ERC-23-0050 (2023)
- Associations of Circulating Estrogens and Estrogen Metabolites with Fecal and Oral Microbiome in Postmenopausal Women in the Ghana Breast Health Study Wu, Z; Pfeiffer, RM; Byrd, DA et al. Microbiol Spectr, DOI://10.1128/spectrum.01572-23 (2023)
- Natural History of Visual Dysfunction in ABCA4 Retinopathy and Its Genetic Correlates Pfau, M; Huryn, LA; Boyle, MP et al. Am J Ophthalmol, DOI://10.1016/j.ajo.2023.05.014 (2023)
- The Vaginal Microbiota of Pregnant Women Varies with Gestational Age, Maternal Age, and Parity Romero, R; Theis, KR; Gomez-Lopez, N et al. Microbiol Spectr, DOI://10.1128/spectrum.03429-22 (2023)
- Experimental NOE, Chemical Shift, and Proline Isomerization Data Provide Detailed Insights into Amelotin Oligomerization Chiliveri, SC; Shen, Y; Baber, JL et al. J Am Chem Soc, DOI://10.1021/jacs.3c05710 (2023)
- Multiomics Analyses Reveal Sex Differences in Mouse Renal Proximal Subsegments Chen, L; Chou, CL; Yang, CR; Knepper, MA; , J Am Soc Nephrol, DOI://10.1681/ASN.0000000000000089 (2023)
- Estimated Prevalence, Tumor Spectrum, and Neurofibromatosis Type 1-Like Phenotype of CDKN2A-Related Melanoma-Astrocytoma Syndrome Sargen, MR; Kim, J; Potjer, TP et al. JAMA Dermatol, DOI://10.1001/jamadermatol.2023.2621 (2023)
- BRG1 HSA domain interactions with BCL7 proteins are critical for remodeling and gene expression Dietrich, N; Trotter, K; Ward, JM; Archer, TK; , Life Sci Alliance, DOI://10.26508/lsa.202201770 (2023)
- Exposure to lung-migrating helminth protects against murine SARS-CoV-2 infection through macrophage-dependent T cell activation Oyesola, OO; Hilligan, KL; Namasivayam, S et al. Sci Immunol, DOI://10.1126/sciimmunol.adf8161 (2023)
- Epigenetic signature of human immune aging in the GESTALT study Roy, R; Kuo, PL; Candia, J et al. Elife, DOI://10.7554/eLife.86136 (2023)
- The Role of FAS Receptor Methylation in Osteosarcoma Metastasis Sun, JM; Chow, WY; Xu, G et al. Int J Mol Sci, DOI://10.3390/ijms241512155 (2023)
- Positional influence on cellular transcriptional identity revealed through spatially segmented single-cell transcriptomics Morse, DB; Michalowski, AM; Ceribelli, M et al. Cell Syst, DOI://10.1016/j.cels.2023.05.003 (2023)
- Deep learning-based decision forest for hereditary clear cell renal cell carcinoma segmentation on MRI Lay, N; Anari, PY; Chaurasia, A et al. Med Phys, DOI://10.1002/mp.16303 (2023)
- A gene duplication of a septin reveals a developmentally regulated filament length control mechanism Cannon, KS; Vargas-Muniz, JM; Billington, N et al. J Cell Biol, DOI://10.1083/jcb.202204063 (2023)
- A novel de novo TP63 mutation in whole-exome sequencing of a Syrian family with Oral cleft and ectrodactyly Simpson, CL; Kimble, DC; Chandrasekharappa, SC et al. Mol Genet Genomic Med, DOI://10.1002/mgg3.2179 (2023)
- Expression quantitative trait methylation analysis elucidates gene regulatory effects of DNA methylation: the Framingham Heart Study Keshawarz, A; Bui, H; Joehanes, R et al. Sci Rep, DOI://10.1038/s41598-023-39936-3 (2023)
- Improving segmentation and detection of lesions in CT scans using intensity distribution supervision Shin, SY; Shen, TC; Summers, RM; , Comput Med Imaging Graph, DOI://10.1016/j.compmedimag.2023.102259 (2023)
- Lesion recognition by XPC, TFIIH and XPA in DNA excision repair Kim, J; Li, CL; Chen, X et al. Nature, DOI://10.1038/s41586-023-05959-z (2023)
- A single N-terminal amino acid determines the distinct roles of histones H3 and H3.3 in the Drosophila male germline stem cell lineage Chandrasekhara, C; Ranjan, R; Urban, JA et al. PLoS Biol, DOI://10.1371/journal.pbio.3002098 (2023)
- A chromosome-scale epigenetic map of the Hydra genome reveals conserved regulators of cell state Cazet, JF; Siebert, S; Little, HM et al. Genome Res, DOI://10.1101/gr.277040.122 (2023)
- T cell intrinsic STAT1 signaling prevents aberrant Th1 responses during acute toxoplasmosis Schultz, AB; Kugler, DG; Nivelo, L et al. Front Immunol, DOI://10.3389/fimmu.2023.1212190 (2023)
- SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck Nigam, N; Bernard, B; Sevilla, S et al. Cell Rep, DOI://10.1016/j.celrep.2023.112823 (2023)
- LAST-seq: single-cell RNA sequencing by direct amplification of single-stranded RNA without prior reverse transcription and second-strand synthesis Lyu, J; Chen, C; , Genome Biol, DOI://10.1186/s13059-023-03025-5 (2023)
- Combined low-frequency brain oscillatory activity and behavior predict future errors in human motor skill Iwane, F; Dash, D; Salamanca-Giron, RF et al. Curr Biol, DOI://10.1016/j.cub.2023.06.040 (2023)
- Estimated Prevalence and Clinical Manifestations of UBA1 Variants Associated With VEXAS Syndrome in a Clinical Population Beck, DB; Bodian, DL; Shah, V et al. JAMA, DOI://10.1001/jama.2022.24836 (2023)
- MLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner Xie, G; Lee, JE; Senft, AD et al. Nat Genet, DOI://10.1038/s41588-023-01356-4 (2023)
- Soluble prefusion-closed HIV-envelope trimers with glycan-covered bases Olia, AS; Cheng, C; Zhou, T et al. iScience, DOI://10.1016/j.isci.2023.107403 (2023)
- Toxic antiphage defense proteins inhibited by intragenic antitoxin proteins Zhong, A; Jiang, X; Hickman, AB et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2307382120 (2023)
- Short hydrocarbon stapled ApoC2-mimetic peptides activate lipoprotein lipase and lower plasma triglycerides in mice Sviridov, D; Dasseux, A; Reimund, M et al. Front Cardiovasc Med, DOI://10.3389/fcvm.2023.1223920 (2023)
- In vivo Polycystin-1 interactome using a novel Pkd1 knock-in mouse model Lin, CC; Menezes, LF; Qiu, J et al. PLoS One, DOI://10.1371/journal.pone.0289778 (2023)
- mRNA location and translation rate determine protein targeting to dual destinations Gasparski, AN; Moissoglu, K; Pallikkuth, S et al. Mol Cell, DOI://10.1016/j.molcel.2023.06.036 (2023)
- Variant STAT4 and Response to Ruxolitinib in an Autoinflammatory Syndrome Baghdassarian, H; Blackstone, SA; Clay, OS et al. N Engl J Med, DOI://10.1056/NEJMoa2202318 (2023)
- Exome-wide association study of treatment-resistant depression suggests novel treatment targets Shah, SB; Peddada, TN; Song, C et al. Sci Rep, DOI://10.1038/s41598-023-38984-z (2023)
- Transcription factor TCF-1 regulates the functions, but not the development, of lymphoid tissue inducer subsets in different tissues Zheng, M; Yao, C; Ren, G et al. Cell Rep, DOI://10.1016/j.celrep.2023.112924 (2023)
- Serology Identifies LIPyV as a Feline Rather than a Human Polyomavirus Kamminga, S; van der Meijden, E; Pesavento, P et al. Viruses, DOI://10.3390/v15071546 (2023)
- Tracking genetic variants in the biomedical literature using LitVar 2.0 Allot, A; Wei, CH; Phan, L et al. Nat Genet, DOI://10.1038/s41588-023-01414-x (2023)
- Crosstalk between ILC2s and Th2 cells varies among mouse models Gurram, RK; Wei, D; Yu, Q et al. Cell Rep, DOI://10.1016/j.celrep.2023.112073 (2023)
- Extreme dynamics in a biomolecular condensate Galvanetto, N; Ivanović, MT; Chowdhury, A et al. Nature, DOI://10.1038/s41586-023-06329-5 (2023)
- A virus-induced circular RNA maintains latent infection of Kaposi's sarcoma herpesvirus Tagawa, T; Oh, D; Dremel, S et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2212864120 (2023)
- Reactivated thyroid hormone receptor β attenuates anaplastic thyroid cancer (ATC) stem cell activity Zhu, X; Zhao, L; Doolittle, WKL; Cheng, SY; , Endocr Relat Cancer, DOI://10.1530/ERC-22-0306 (2023)
- Long wavelength-sensing cones of zebrafish retina exhibit multiple layers of transcriptional heterogeneity Farre, AA; Sun, C; Starostik, MR et al. Front Cell Neurosci, DOI://10.3389/fncel.2023.1214084 (2023)
- Regulation of endogenous retrovirus-derived regulatory elements by GATA2/3 and MSX2 in human trophoblast stem cells Du, C; Jiang, J; Li, Y et al. Genome Res, DOI://10.1101/gr.277150.122 (2023)
- Questionnaire-Based Polyexposure Assessment Outperforms Polygenic Scores for Classification of Type 2 Diabetes in a Multiancestry Cohort Akhtari, FS; Lloyd, D; Burkholder, A et al. Diabetes Care, DOI://10.2337/dc22-0295 (2023)
- Architectural basis for cylindrical self-assembly governing Plk4-mediated centriole duplication in human cells Il Ahn, J; Zhang, L; Ravishankar, H et al. Commun Biol, DOI://10.1038/s42003-023-05067-8 (2023)
- RNA exosome ribonuclease DIS3 degrades Pou6f1 to promote mouse pre-implantation cell differentiation Wu, D; Dean, J; , Cell Rep, DOI://10.1016/j.celrep.2023.112047 (2023)
- Identifying sources of human interictal discharges with travelling wave and white matter propagation Withers, CP; Diamond, JM; Yang, B et al. Brain, DOI://10.1093/brain/awad259 (2023)
- Multilevel human secondary lymphoid immune system compartmentalization revealed by complementary imaging approaches Oyler, BL; Valencia-Dávila, JA; Moysi, E et al. iScience, DOI://10.1016/j.isci.2023.107261 (2023)
- 2-Hydroxypropyl-β-Cyclodextrin Treatment Induces Modest Immune Activation in Healthy Rhesus Macaques Ortiz, AM; Castello Casta, F; Rahmberg, A et al. J Virol, DOI://10.1128/jvi.00600-23 (2023)
- NF-κB subunits direct kinetically distinct transcriptional cascades in antigen receptor-activated B cells Zhao, M; Chauhan, P; Sherman, CA et al. Nat Immunol, DOI://10.1038/s41590-023-01561-7 (2023)
- Senescence-induced cellular reprogramming drives cnidarian whole-body regeneration Salinas-Saavedra, M; Febrimarsa, ; Krasovec, G et al. Cell Rep, DOI://10.1016/j.celrep.2023.112687 (2023)
- SOX9 is a key component of RUNX2-regulated transcriptional circuitry in osteosarcoma Kim, YI; Tseng, YC; Ayaz, G et al. Cell Biosci, DOI://10.1186/s13578-023-01088-2 (2023)
- Multi-tiered approach to detect autoimmune cross-reactivity of therapeutic T cell receptors Ishii, K; Davies, JS; Sinkoe, AL et al. Sci Adv, DOI://10.1126/sciadv.adg9845 (2023)
- PRDM10 RCC: A Birt-Hogg-Dubé-like Syndrome Associated With Lipoma and Highly Penetrant, Aggressive Renal Tumors Morphologically Resembling Type 2 Papillary Renal Cell Carcinoma Schmidt, LS; Vocke, CD; Ricketts, CJ et al. Urology, DOI://10.1016/j.urology.2023.04.035 (2023)
- The genome of antibiotic-producing colonies of the Pelagophyte alga Chrysophaeum taylorii reveals a diverse and non-canonical capacity for secondary metabolism Davison, JR; Rajwani, R; Zhao, G; Bewley, CA; , Sci Rep, DOI://10.1038/s41598-023-38042-8 (2023)
- Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding Lannes, L; Furman, CM; Hickman, AB; Dyda, F; , Nat Commun, DOI://10.1038/s41467-023-40210-3 (2023)
- Whole-genome methylation analysis of aging human tissues identifies age-related changes in developmental and neurological pathways Tharakan, R; Ubaida-Mohien, C; Dunn, C et al. Aging Cell, DOI://10.1111/acel.13847 (2023)
- Manifold learning for fMRI time-varying functional connectivity Gonzalez-Castillo, J; Fernandez, IS; Lam, KC et al. Front Hum Neurosci, DOI://10.3389/fnhum.2023.1134012 (2023)
- eEF2 diphthamide modification restrains spurious frameshifting to maintain translational fidelity Shin, BS; Ivanov, IP; Kim, JR et al. Nucleic Acids Res, DOI://10.1093/nar/gkad461 (2023)
- Primary oxidative phosphorylation defects lead to perturbations in the human B cell repertoire Gordon-Lipkin, EM; Banerjee, P; Franco, JLM et al. Front Immunol, DOI://10.3389/fimmu.2023.1142634 (2023)
- BOLD Response is more than just magnitude: Improving detection sensitivity through capturing hemodynamic profiles Chen, G; Taylor, PA; Reynolds, RC et al. Neuroimage, DOI://10.1016/j.neuroimage.2023.120224 (2023)
- Integrative analysis of individual-level data and high-dimensional summary statistics Fu, S; Deng, L; Zhang, H et al. Bioinformatics, DOI://10.1093/bioinformatics/btad156 (2023)
- Integrating massive RNA-seq data to elucidate transcriptome dynamics in Drosophila melanogaster Hu Qian, S; Shi, MW; Wang, DY et al. Brief Bioinform, DOI://10.1093/bib/bbad177 (2023)
- Optimized quantification of intra-host viral diversity in SARS-CoV-2 and influenza virus sequence data Roder, AE; Johnson, KEE; Knoll, M et al. mBio, DOI://10.1128/mbio.01046-23 (2023)
- AIONER: all-in-one scheme-based biomedical named entity recognition using deep learning Luo, L; Wei, CH; Lai, PT et al. Bioinformatics, DOI://10.1093/bioinformatics/btad310 (2023)
- Haplotype-based analysis resolves missing heritability in oculocutaneous albinism type 1B Loftus, SK; Gillis, MF; Lundh, L et al. Am J Hum Genet, DOI://10.1016/j.ajhg.2023.05.012 (2023)
- Stiff matrix induces exosome secretion to promote tumour growth Wu, B; Liu, DA; Guan, L et al. Nat Cell Biol, DOI://10.1038/s41556-023-01092-1 (2023)
- Analysis of several common APOBEC-type mutations in bladder tumors suggests links to viral infection Rao, N; Starrett, GJ; Piaskowski, ML et al. Cancer Prev Res (Phila), DOI://10.1158/1940-6207.CAPR-23-0112 (2023)
- Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex Hayne, CK; Butay, KJU; Stewart, ZD et al. Nat Struct Mol Biol, DOI://10.1038/s41594-023-00991-z (2023)
- Author Correction: The power of genetic diversity in genome-wide association studies of lipids Graham, SE; Clarke, SL; Wu, KH et al. Nature, DOI://10.1038/s41586-023-06194-2 (2023)
- The Combination of Trametinib and Ganitumab is Effective in RAS-Mutated PAX-Fusion Negative Rhabdomyosarcoma Models Hebron, KE; Wan, X; Roth, JS et al. Clin Cancer Res, DOI://10.1158/1078-0432.CCR-22-1646 (2023)
- A Phase II Trial of Guadecitabine in Children and Adults with SDH-Deficient GIST, Pheochromocytoma, Paraganglioma, and HLRCC-Associated Renal Cell Carcinoma Ligon, JA; Sundby, RT; Wedekind, MF et al. Clin Cancer Res, DOI://10.1158/1078-0432.CCR-22-2168 (2023)
- Cathepsin W restrains peripheral regulatory T cells for mucosal immune quiescence Li, J; Chen, Z; Kim, G et al. Sci Adv, DOI://10.1126/sciadv.adf3924 (2023)
- Race/ethnicity-stratified fine-mapping of the MHC locus reveals genetic variants associated with late-onset asthma Lee, EY; Choi, W; Burkholder, AB et al. Front Genet, DOI://10.3389/fgene.2023.1173676 (2023)
- rWTC-MBTA: autologous vaccine prevents metastases via antitumor immune responses Ye, J; Wang, H; Medina, R et al. J Exp Clin Cancer Res, DOI://10.1186/s13046-023-02744-8 (2023)
- Gut dysbiosis in Thai intrahepatic cholangiocarcinoma and hepatocellular carcinoma Pomyen, Y; Chaisaingmongkol, J; Rabibhadana, S et al. Sci Rep, DOI://10.1038/s41598-023-38307-2 (2023)
- Structural and photophysical characterization of the small ultra-red fluorescent protein Maiti, A; Buffalo, CZ; Saurabh, S et al. Nat Commun, DOI://10.1038/s41467-023-39776-9 (2023)
- Noncoding RNA circuitry in melanoma onset, plasticity, and therapeutic response Grafanaki, K; Grammatikakis, I; Ghosh, A et al. Pharmacol Ther, DOI://10.1016/j.pharmthera.2023.108466 (2023)
- GATA3 induces the pathogenicity of Th17 cells via regulating GM-CSF expression Butcher, MJ; Gurram, RK; Zhu, X et al. Front Immunol, DOI://10.3389/fimmu.2023.1186580 (2023)
- Modification of a Conventional Deep Learning Model to Classify Simulated Breathing Patterns: A Step toward Real-Time Monitoring of Patients with Respiratory Infectious Diseases Park, J; Mah, AJ; Nguyen, T et al. Sensors (Basel), DOI://10.3390/s23125592 (2023)
- Modulation of WNT, Activin/Nodal, and MAPK Signaling Pathways Increases Arterial Hemogenic Endothelium and Hematopoietic Stem/Progenitor Cell Formation During Human iPSC Differentiation Li, Y; Ding, J; Araki, D et al. Stem Cells, DOI://10.1093/stmcls/sxad040 (2023)
- Cerebrospinal Fluid Protein Biomarker Discovery in CLN3 Dang Do, AN; Sleat, DE; Campbell, K et al. J Proteome Res, DOI://10.1021/acs.jproteome.3c00199 (2023)
- Clinical, genetic, and structural characterization of a novel TUBB4B tubulinopathy McFadden, JR; Tolete, CDP; Huang, Y et al. Mol Genet Metab Rep, DOI://10.1016/j.ymgmr.2023.100990 (2023)
- GRL-142 binds to and impairs HIV-1 integrase nuclear localization signal and potently suppresses highly INSTI-resistant HIV-1 variants Aoki, M; Aoki-Ogata, H; Bulut, H et al. Sci Adv, DOI://10.1126/sciadv.adg2955 (2023)
- A longitudinal transcriptomic analysis from unfed to post-engorgement midguts of adult female Ixodes scapularis Lu, S; Martins, LA; Kotál, J et al. Sci Rep, DOI://10.1038/s41598-023-38207-5 (2023)
- Residues from Homologous Transmembrane Helices 4 and 10 Are Critical for P-Glycoprotein (ABCB1)-Mediated Drug Transport Rahman, H; Ware, MJ; Sajid, A et al. Cancers (Basel), DOI://10.3390/cancers15133459 (2023)
- Improve the model of disease subtype heterogeneity by leveraging external summary data Fu, S; Purdue, MP; Zhang, H et al. PLoS Comput Biol, DOI://10.1371/journal.pcbi.1011236 (2023)
- Roving methyltransferases generate a mosaic epigenetic landscape and influence evolution in Bacteroides fragilis group Tisza, MJ; Smith, DDN; Clark, AE et al. Nat Commun, DOI://10.1038/s41467-023-39892-6 (2023)
- mRNA decapping activators Pat1 and Dhh1 regulate transcript abundance and translation to tune cellular responses to nutrient availability Vijjamarri, AK; Gupta, N; Onu, C et al. Nucleic Acids Res, DOI://10.1093/nar/gkad584 (2023)
- CellMinerCDB: NCATS Is a Web-Based Portal Integrating Public Cancer Cell Line Databases for Pharmacogenomic Explorations Reinhold, WC; Wilson, K; Elloumi, F et al. Cancer Res, DOI://10.1158/0008-5472.CAN-22-2996 (2023)
- C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection Desai, JV; Kumar, D; Freiwald, T et al. Cell, DOI://10.1016/j.cell.2023.04.031 (2023)
- MYC determines lineage commitment in KRAS-driven primary liver cancer development D'Artista, L; Moschopoulou, AA; Barozzi, I et al. J Hepatol, DOI://10.1016/j.jhep.2023.02.039 (2023)
- Epitope-level profiling in children with mitochondrial disease reveals limitations in the antibacterial antibody repertoire Gordon-Lipkin, EM; Banerjee, P; Thompson, E et al. Mol Genet Metab, DOI://10.1016/j.ymgme.2023.107581 (2023)
- Transcriptome-based measurement of CD8+ T cell age and its applications Weng, NP Trends Immunol, DOI://10.1016/j.it.2023.05.005 (2023)
- Proteostasis Modulation in Germline Missense von Hippel Lindau Disease Chittiboina, P; Mandal, D; Bugarini, A et al. Clin Cancer Res, DOI://10.1158/1078-0432.CCR-22-3651 (2023)
- A network of DZF proteins controls alternative splicing regulation and fidelity Haque, N; Will, A; Cook, AG; Hogg, JR; , Nucleic Acids Res, DOI://10.1093/nar/gkad351 (2023)
- Hi-TrAC detects active sub-TADs and reveals internal organizations of super-enhancers Cao, Y; Liu, S; Cui, K et al. Nucleic Acids Res, DOI://10.1093/nar/gkad378 (2023)
- A Therapeutically Targetable NOTCH1-SIRT1-KAT7 Axis in T-cell Leukemia Lancho, O; Singh, A; da Silva-Diz, V et al. Blood Cancer Discov, DOI://10.1158/2643-3230.BCD-22-0098 (2023)
- Extensive diversity in RNA termination and regulation revealed by transcriptome mapping for the Lyme pathogen Borrelia burgdorferi Petroni, E; Esnault, C; Tetreault, D et al. Nat Commun, DOI://10.1038/s41467-023-39576-1 (2023)
- Germline loss-of-function PAM variants are enriched in subjects with pituitary hypersecretion Trivellin, G; Daly, AF; Hernández-Ramírez, LC et al. Front Endocrinol (Lausanne), DOI://10.3389/fendo.2023.1166076 (2023)
- Dynamic switching of transcriptional regulators between two distinct low-mobility chromatin states Wagh, K; Stavreva, DA; Jensen, RAM et al. Sci Adv, DOI://10.1126/sciadv.ade1122 (2023)
- NUP98::Nsd1 and FLT3-ITD collaborate to generate acute myeloid leukemia Matsukawa, T; Yin, M; Nigam, N et al. Leukemia, DOI://10.1038/s41375-023-01913-0 (2023)
- ChromDL: a next-generation regulatory DNA classifier Hill, C; Hudaiberdiev, S; Ovcharenko, I; , Bioinformatics, DOI://10.1093/bioinformatics/btad217 (2023)
- Distinct Genomic Landscape of Lung Adenocarcinoma from Household Use of Smoky Coal Zhang, T; Hoang, PH; Wong, JYY et al. Am J Respir Crit Care Med, DOI://10.1164/rccm.202302-0340LE (2023)
- Eight Unexpected Selenoprotein Families in Organometallic Biochemistry in Clostridium difficile, in ABC Transport, and in Methylmercury Biosynthesis Haft, DH; Gwadz, M; , J Bacteriol, DOI://10.1128/jb.00259-22 (2023)
- Tumor biology and immune infiltration define primary liver cancer subsets linked to overall survival after immunotherapy Budhu, A; Pehrsson, EC; He, A et al. Cell Rep Med, DOI://10.1016/j.xcrm.2023.101052 (2023)
- An efficient genotyper and star-allele caller for pharmacogenomics Hari, A; Zhou, Q; Gonzaludo, N et al. Genome Res, DOI://10.1101/gr.277075.122 (2023)
- Expanded analysis of high-grade astrocytoma with piloid features identifies an epigenetically and clinically distinct subtype associated with neurofibromatosis type 1 Cimino, PJ; Ketchum, C; Turakulov, R et al. Acta Neuropathol, DOI://10.1007/s00401-022-02513-5 (2023)
- Reliability of Admission Procalcitonin Testing for Capturing Bacteremia Across the Sepsis Spectrum: Real-World Utilization and Performance Characteristics, 65 U.S. Hospitals, 2008-2017 Lawandi, A; Oshiro, M; Warner, S et al. Crit Care Med, DOI://10.1097/CCM.0000000000005968 (2023)
- Genome-wide structural variant analysis identifies risk loci for non-Alzheimer's dementias Kaivola, K; Chia, R; Ding, J et al. Cell Genom, DOI://10.1016/j.xgen.2023.100316 (2023)
- A landscape of response to drug combinations in non-small cell lung cancer Nair, NU; Greninger, P; Zhang, X et al. Nat Commun, DOI://10.1038/s41467-023-39528-9 (2023)
- Ion channel selectivity through ion-modulated changes of selectivity filter pKa values Chen, AY; Brooks, BR; Damjanovic, A; , Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2220343120 (2023)
- Germline genetic variants and pediatric rhabdomyosarcoma outcomes: a report from the Children's Oncology Group Martin-Giacalone, BA; Richard, MA; Scheurer, ME et al. J Natl Cancer Inst, DOI://10.1093/jnci/djad055 (2023)
- Structural mechanism of LIN28B nucleosome targeting by OCT4 Guan, R; Lian, T; Zhou, BR et al. Mol Cell, DOI://10.1016/j.molcel.2023.05.030 (2023)
- The molecular basis of heterochromatin assembly and epigenetic inheritance Grewal, SIS Mol Cell, DOI://10.1016/j.molcel.2023.04.020 (2023)
- Decapping factor Dcp2 controls mRNA abundance and translation to adjust metabolism and filamentation to nutrient availability Vijjamarri, AK; Niu, X; Vandermeulen, MD et al. Elife, DOI://10.7554/eLife.85545 (2023)
- Divergent Transcriptomic Effects of Allopregnanolone in Postpartum Depression Rudzinskas, SA; Mazzu, MA; Schiller, CE et al. Genes (Basel), DOI://10.3390/genes14061234 (2023)
- Cellular Diversity in Human Subgenual Anterior Cingulate and Dorsolateral Prefrontal Cortex by Single-Nucleus RNA-Sequencing Kim, B; Kim, D; Schulmann, A et al. J Neurosci, DOI://10.1523/JNEUROSCI.0830-22.2023 (2023)
- Structure of Complex III with Bound Antimalarial Agent CK-2-68 Provides Insights into Selective Inhibition of Plasmodium Cytochrome bc1 Complexes Esser, L; Zhou, F; Zeher, A et al. J Biol Chem, DOI://10.1016/j.jbc.2023.104860 (2023)
- Large-scale rare variant burden testing in Parkinson's disease Makarious, MB; Lake, J; Pitz, V et al. Brain, DOI://10.1093/brain/awad214 (2023)
- Germ cell-specific eIF4E1b regulates maternal mRNA translation to ensure zygotic genome activation Yang, G; Xin, Q; Feng, I et al. Genes Dev, DOI://10.1101/gad.350400.123 (2023)
- A protocol for visualization of murine in situ neurovascular interfaces Dang, DD; Chandrashekhar, V; Chandrashekhar, V et al. STAR Protoc, DOI://10.1016/j.xpro.2023.102367 (2023)
- Effect of motion, cortical orientation and spatial resolution on quantitative imaging of cortical R2* and magnetic susceptibility at 0.3 mm in-plane resolution at 7 T van Gelderen, P; Li, X; de Zwart, JA et al. Neuroimage, DOI://10.1016/j.neuroimage.2023.119992 (2023)
- The NanoFlow Repository Arce, JE; Welsh, JA; Cook, S et al. Bioinformatics, DOI://10.1093/bioinformatics/btad368 (2023)
- Tight basis cycle representatives for persistent homology of large biological data sets Aggarwal, M; Periwal, V; , PLoS Comput Biol, DOI://10.1371/journal.pcbi.1010341 (2023)
- Signaling mechanisms in renal compensatory hypertrophy revealed by multi-omics Kikuchi, H; Chou, CL; Yang, CR et al. Nat Commun, DOI://10.1038/s41467-023-38958-9 (2023)
- Master regulator activity QTL protocol to implicate regulatory pathways potentially mediating GWAS signals using eQTL data Hoskins, JW; Christensen, TA; Amundadottir, LT; , STAR Protoc, DOI://10.1016/j.xpro.2023.102362 (2023)
- The beneficial effects of commensal E. coli for colon epithelial cell recovery are related with Formyl peptide receptor 2 (Fpr2) in epithelial cells Chen, K; McCulloch, J; Das Neves, R et al. Gut Pathog, DOI://10.1186/s13099-023-00557-w (2023)
- An updated catalog of CTCF variants associated with neurodevelopmental disorder phenotypes Price, E; Fedida, LM; Pugacheva, EM et al. Front Mol Neurosci, DOI://10.3389/fnmol.2023.1185796 (2023)
- Editorial: Demonstrating quality control (QC) procedures in fMRI Taylor, PA; Glen, DR; Reynolds, RC et al. Front Neurosci, DOI://10.3389/fnins.2023.1205928 (2023)
- Three-Dimensional Reconstruction of the Hepatitis C Virus Envelope Glycoprotein E1E2 Heterodimer by Electron Microscopic Analysis Kanai, T; Hu, Z; Yang, R et al. J Virol, DOI://10.1128/jvi.01788-22 (2023)
- Multiple models for outbreak decision support in the face of uncertainty Shea, K; Borchering, RK; Probert, WJM et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2207537120 (2023)
- Identification of epigenetic modulators as determinants of nuclear size and shape Schibler, AC; Jevtic, P; Pegoraro, G et al. Elife, DOI://10.7554/eLife.80653 (2023)
- Simulated dynamic cholesterol redistribution favors membrane fusion pore constriction Beaven, AH; Sapp, K; Sodt, AJ; , Biophys J, DOI://10.1016/j.bpj.2022.12.024 (2023)
- Disrupted Dynamic Interactions Between Large-Scale Brain Networks in Cocaine Users Are Associated With Dependence Severity Zhai, T; Gu, H; Salmeron, BJ et al. Biol Psychiatry Cogn Neurosci Neuroimaging, DOI://10.1016/j.bpsc.2022.08.010 (2023)
- Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization Sastry, M; Changela, A; Gorman, J et al. J Virol, DOI://10.1128/jvi.01604-22 (2023)
- Characterization of serotonin-5-HTR1E signaling pathways and its role in cell survival Sharma, VK; Campbell, K; Yang, X et al. FASEB J, DOI://10.1096/fj.202300128R (2023)
- Constitutive and conditional deletion reveals distinct phenotypes driven by developmental versus neurotransmitter actions of the neuropeptide PACAP Bakalar, D; Gavrilova, O; Jiang, SZ et al. J Neuroendocrinol, DOI://10.1111/jne.13286 (2023)
- Distributing task-related neural activity across a cortical network through task-independent connections Kim, CM; Finkelstein, A; Chow, CC et al. Nat Commun, DOI://10.1038/s41467-023-38529-y (2023)
- 3DVizSNP: a tool for rapidly visualizing missense mutations identified in high throughput experiments in iCn3D Sierk, M; Ratnayake, S; Wagle, MM et al. BMC Bioinformatics, DOI://10.1186/s12859-023-05370-5 (2023)
- Co-crystal structures of the fluorogenic aptamer Beetroot show that close homology may not predict similar RNA architecture Passalacqua, LFM; Starich, MR; Link, KA et al. Nat Commun, DOI://10.1038/s41467-023-38683-3 (2023)
- Cell surface marker-based capture of neoantigen-reactive CD8+ T-cell receptors from metastatic tumor digests Chatani, PD; Lowery, FJ; Parikh, NB et al. J Immunother Cancer, DOI://10.1136/jitc-2022-006264 (2023)
- Efflux pump gene amplifications bypass necessity of multiple target mutations for resistance against dual-targeting antibiotic Silva, KPT; Sundar, G; Khare, A; , Nat Commun, DOI://10.1038/s41467-023-38507-4 (2023)
- Dynamic chromatin accessibility licenses STAT5- and STAT6-dependent innate-like function of Th9 cells to promote allergic inflammation Son, A; Meylan, F; Gomez-Rodriguez, J et al. Nat Immunol, DOI://10.1038/s41590-023-01501-5 (2023)
- Cumulative Genetic Score and C9orf72 Repeat Status Independently Contribute to Amyotrophic Lateral Sclerosis Risk in 2 Case-Control Studies Dou, J; Bakulski, K; Guo, K et al. Neurol Genet, DOI://10.1212/NXG.0000000000200079 (2023)
- Immunology and immunotherapy of cholangiocarcinoma Greten, TF; Schwabe, R; Bardeesy, N et al. Nat Rev Gastroenterol Hepatol, DOI://10.1038/s41575-022-00741-4 (2023)
- Restraint of IFN-γ expression through a distal silencer CNS-28 for tissue homeostasis Cui, K; Chen, Z; Cao, Y et al. Immunity, DOI://10.1016/j.immuni.2023.03.006 (2023)
- Tetramerization of STAT5 regulates monocyte differentiation and the dextran sulfate sodium-induced colitis in mice Monaghan, KL; Zheng, W; Akhter, H et al. Front Immunol, DOI://10.3389/fimmu.2023.1117828 (2023)
- Optimizing cancer immunotherapy response prediction by tumor aneuploidy score and fraction of copy number alterations Chang, TG; Cao, Y; Shulman, ED et al. NPJ Precis Oncol, DOI://10.1038/s41698-023-00408-6 (2023)
- Cryo-EM structures of anti-malarial antibody L9 with circumsporozoite protein reveal trimeric L9 association and complete 27-residue epitope Tripathi, P; Bender, MF; Lei, H et al. Structure, DOI://10.1016/j.str.2023.02.009 (2023)
- An Integrative Multiomics Framework for Identification of Therapeutic Targets in Pulmonary Fibrosis Arif, M; Basu, A; Wolf, KM et al. Adv Sci (Weinh), DOI://10.1002/advs.202207454 (2023)
- Identification of a covert evolutionary pathway between two protein folds Chakravarty, D; Sreenivasan, S; Swint-Kruse, L; Porter, LL; , Nat Commun, DOI://10.1038/s41467-023-38519-0 (2023)
- Synthesis of novel entecavir analogues having 4'-cyano-6''-fluoromethylenecyclopentene skeletons as an aglycone moiety as highly potent and long-acting anti-hepatitis B virus agent Kumamoto, H; Higashi-Kuwata, N; Hayashi, S et al. RSC Adv, DOI://10.1039/d3ra01750h (2023)
- Interferon-gamma is quintessential for NOS2 and COX2 expression in ER- breast tumors that lead to poor outcome Cheng, RYS; Ridnour, LA; Wink, AL et al. Cell Death Dis, DOI://10.1038/s41419-023-05834-9 (2023)
- Highlight results, don't hide them: Enhance interpretation, reduce biases and improve reproducibility Taylor, PA; Reynolds, RC; Calhoun, V et al. Neuroimage, DOI://10.1016/j.neuroimage.2023.120138 (2023)
- Persistent Frustration-Induced Reconfigurations of Brain Networks Predict Individual Differences in Irritability Linke, JO; Haller, SP; Xu, EP et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2022.11.009 (2023)
- A hyper-quiescent chromatin state formed during aging is reversed by regeneration Yang, N; Occean, JR; Melters, DP et al. Mol Cell, DOI://10.1016/j.molcel.2023.04.005 (2023)
- Variants of LRP2, encoding a multifunctional cell-surface endocytic receptor, associated with hearing loss and retinal dystrophy Faridi, R; Yousaf, R; Gu, S et al. Clin Genet, DOI://10.1111/cge.14312 (2023)
- Ca2+ efflux facilitated by co-transport of inorganic phosphate anion in the H+/Ca2+ antiporter YfkE Niu, W; Zhou, W; Lu, S et al. Commun Biol, DOI://10.1038/s42003-023-04944-6 (2023)
- Physiological changes in bilayer thickness induced by cholesterol control GPCR rhodopsin function Soubias, O; Sodt, AJ; Teague, WE et al. Biophys J, DOI://10.1016/j.bpj.2022.11.2937 (2023)
- TFEB and TFE3 drive kidney cystogenesis and tumorigenesis Di Malta, C; Zampelli, A; Granieri, L et al. EMBO Mol Med, DOI://10.15252/emmm.202216877 (2023)
- Surface viscosities of lipid bilayers determined from equilibrium molecular dynamics simulations Fitzgerald, JE; Venable, RM; Pastor, RW; Lyman, ER; , Biophys J, DOI://10.1016/j.bpj.2023.01.038 (2023)
- Initiation and evolution of pores formed by influenza fusion peptides probed by lysolipid inclusion Rice, A; Zimmerberg, J; Pastor, RW; , Biophys J, DOI://10.1016/j.bpj.2022.12.029 (2023)
- Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population Shi, J; Shiraishi, K; Choi, J et al. Nat Commun, DOI://10.1038/s41467-023-38196-z (2023)
- Aneuploidy effects on human gene expression across three cell types Liu, S; Akula, N; Reardon, PK et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2218478120 (2023)
- exRNA-eCLIP intersection analysis reveals a map of extracellular RNA binding proteins and associated RNAs across major human biofluids and carriers LaPlante, EL; Stürchler, A; Fullem, R et al. Cell Genom, DOI://10.1016/j.xgen.2023.100303 (2023)
- A novel, bioinformatically informed highly sensitive NAAT assay for the diagnosis of loiasis and its use for detection of circulating cell free DNA Bennuru, S; Kodua, F; Drame, PM et al. J Infect Dis, DOI://10.1093/infdis/jiad186 (2023)
- Periaqueductal gray matter and medial prefrontal cortex reflect negative prediction errors during differential conditioning Gorka, AX; Philips, RT; Torrisi, S et al. Soc Cogn Affect Neurosci, DOI://10.1093/scan/nsad025 (2023)
- Inflammatory and interferon gene expression signatures in patients with mitochondrial disease Warren, EB; Gordon-Lipkin, EM; Cheung, F et al. J Transl Med, DOI://10.1186/s12967-023-04180-w (2023)
- Influenza A viruses in gulls in landfills and freshwater habitats in Minnesota, United States Rasmussen, EA; Czaja, A; Cuthbert, FJ et al. Front Genet, DOI://10.3389/fgene.2023.1172048 (2023)
- Differences in Merkel Cell Carcinoma Presentation and Outcomes Among Racial and Ethnic Groups Mohsin, N; Martin, MR; Reed, DJ et al. JAMA Dermatol, DOI://10.1001/jamadermatol.2023.0061 (2023)
- Phenotypic plasticity and reduced tissue retention of exhausted tumor-infiltrating T cells following neoadjuvant immunotherapy in head and neck cancer Sievers, C; Craveiro, M; Friedman, J et al. Cancer Cell, DOI://10.1016/j.ccell.2023.03.014 (2023)
- Cannabidiol sensitizes TRPV2 channels to activation by 2-APB Gochman, A; Tan, XF; Bae, C et al. Elife, DOI://10.7554/eLife.86166 (2023)
- Constitutive and conditional PACAP deletion reveals distinct phenotypes driven by developmental versus neurotransmitter actions of PACAP Dana Bakalar, Oksana Gavrilova, Sunny Z. Jiang, Hai-ying Zhang, Snehashis Roy, Sarah K. Williams, Naili Liu, Stephen Wisser, Ted B. Usdin, Lee E. Eiden Journal of Neuroendocrinology, 10.1111/jne.13286 (2023)
- AI-based CT Body Composition Identifies Myosteatosis as Key Mortality Predictor in Asymptomatic Adults Maxime Nachit , Yves Horsmans, Ronald M. Summers, Isabelle A. Leclercq, Perry J. Pickhardt Radiology, doi://10.1148/radiol.222008 (2023)
- Protocol for using single-cell sequencing to study the heterogeneity of NF1 nerve sheath tumors from clinical biospecimens Zhang, X; Gopalan, V; Syed, N et al. STAR Protoc, DOI://10.1016/j.xpro.2023.102297 (2023)
- Tracking the emergence of antigenic variants in influenza A virus epidemics in Brazil Pillai, TK; Johnson, KE; Song, T et al. Virus Evol, DOI://10.1093/ve/vead027 (2023)
- Genome-Wide Analysis of Structural Variants in Parkinson Disease Billingsley, KJ; Ding, J; Jerez, PA et al. Ann Neurol, DOI://10.1002/ana.26608 (2023)
- Country-level gender inequality is associated with structural differences in the brains of women and men Zugman, A; Alliende, LM; Medel, V et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2218782120 (2023)
- Working memory and reward increase the accuracy of animal location encoding in the medial prefrontal cortex Ma, X; Zheng, C; Chen, Y et al. Cereb Cortex, DOI://10.1093/cercor/bhac205 (2023)
- Genome and Genetic Engineering of the House Cricket (Acheta domesticus): A Resource for Sustainable Agriculture Dossey, AT; Oppert, B; Chu, FC et al. Biomolecules, DOI://10.3390/biom13040589 (2023)
- Label-free cleared tissue microscopy and machine learning for 3D histopathology of biomaterial implants Ngo, TB; DeStefano, S; Liu, J et al. J Biomed Mater Res A, DOI://10.1002/jbm.a.37515 (2023)
- Oncogenic CDK13 Mutations Impede Nuclear RNA Surveillance Insco, ML; Abraham, BJ; Dubbury, SJ et al. Science, DOI://10.1126/science.abn7625 (2023)
- Genetic risk factor clustering within and across neurodegenerative diseases Koretsky, MJ; Alvarado, C; Makarious, MB et al. Brain, DOI://10.1093/brain/awad161 (2023)
- Generalized Fringe-to-Phase Framework for Single-Shot 3D Reconstruction Integrating Structured Light with Deep Learning Nguyen, AH; Ly, KL; Lam, VK; Wang, Z; , Sensors (Basel), DOI://10.3390/s23094209 (2023)
- Ancestral and environmental patterns in the association between triglycerides and other cardiometabolic risk factors Meeks, KAC; Bentley, AR; Agyemang, C et al. EBioMedicine, DOI://10.1016/j.ebiom.2023.104548 (2023)
- Anti-Cancer Activity of Verteporfin in Cholangiocarcinoma Golino, JL; Wang, X; Bian, J et al. Cancers (Basel), DOI://10.3390/cancers15092454 (2023)
- Epigenetic Regulation in Primary CNS Tumors: An Opportunity to Bridge Old and New WHO Classifications Dang, DD; Rosenblum, JS; Shah, AH et al. Cancers (Basel), DOI://10.3390/cancers15092511 (2023)
- Comparative Analysis of the Humoral Immune Response to the EBV Proteome across EBV-Related Malignancies Argirion, I; Pfeiffer, RM; Proietti, C et al. Cancer Epidemiol Biomarkers Prev, DOI://10.1158/1055-9965.EPI-22-0452 (2023)
- Blood-feeding adaptations and virome assessment of the poultry red mite Dermanyssus gallinae guided by RNA-seq Ribeiro, JM; Hartmann, D; Bartošová-Sojková, P et al. Commun Biol, DOI://10.1038/s42003-023-04907-x (2023)
- Evolink: a phylogenetic approach for rapid identification of genotype-phenotype associations in large-scale microbial multispecies data Yang, Y; Jiang, X; , Bioinformatics, DOI://10.1093/bioinformatics/btad215 (2023)
- NF-κB Signaling Modulates miR-452-5p and miR-335-5p Expression to Functionally Decrease Epithelial Ovarian Cancer Progression in Tumor-Initiating Cells Kamdar, RD; Harrington, BS; Attar, E et al. Int J Mol Sci, DOI://10.3390/ijms24097826 (2023)
- Virtual screening of ultra-large chemical libraries identifies cell-permeable small-molecule inhibitors of a "non-druggable" target, STAT3 N-terminal domain Bonilla, PA; Hoop, CL; Stefanisko, K et al. Front Oncol, DOI://10.3389/fonc.2023.1144153 (2023)
- Genomic analysis, immunomodulation and deep phenotyping of patients with nodding syndrome Soldatos, A; Nutman, TB; Johnson, T et al. Brain, DOI://10.1093/brain/awac357 (2023)
- Recombination between heterologous human acrocentric chromosomes Guarracino, A; Buonaiuto, S; de Lima, LG et al. Nature, DOI://10.1038/s41586-023-05976-y (2023)
- The landscape of health disparities in the UK Biobank Nagar, SD; Jordan, IK; Mariño-Ramírez, L; , Database (Oxford), DOI://10.1093/database/baad026 (2023)
- First-time identification of a KIF5B-NTRK2 fusion in extraventricular neurocytoma Gubbiotti, MA; Santi, M; Storm, PB et al. J Neuropathol Exp Neurol, DOI://10.1093/jnen/nlad002 (2023)
- Comparative Analysis of Transcriptome Profiles Reveals Distinct and Organ-Dependent Genomic and Nongenomic Actions of Thyroid Hormone in Xenopus tropicalis Tadpoles Wang, S; Shibata, Y; Tanizaki, Y et al. Thyroid, DOI://10.1089/thy.2022.0469 (2023)
- Lipid flipping in the omega-3 fatty-acid transporter Nguyen, C; Lei, HT; Lai, LTF et al. Nat Commun, DOI://10.1038/s41467-023-37702-7 (2023)
- Drude Polarizable Lipid Force Field with Explicit Treatment of Long-Range Dispersion: Parametrization and Validation for Saturated and Monounsaturated Zwitterionic Lipids Yu, Y; Venable, RM; Thirman, J et al. J Chem Theory Comput, DOI://10.1021/acs.jctc.3c00203 (2023)
- Impact of overweight and obesity on US renal cell carcinoma incidence trends (1995-2018) Luo, Q; Hofmann, JN; Pfeiffer, RM et al. Int J Cancer, DOI://10.1002/ijc.34516 (2023)
- Rye: genetic ancestry inference at biobank scale Conley, AB; Rishishwar, L; Ahmad, M et al. Nucleic Acids Res, DOI://10.1093/nar/gkad149 (2023)
- Spurious intragenic transcription is a feature of mammalian cellular senescence and tissue aging Sen, P; Donahue, G; Li, C et al. Nat Aging, DOI://10.1038/s43587-023-00384-3 (2023)
- Liver development during Xenopus tropicalis metamorphosis is controlled by T3-activation of WNT signaling Tanizaki, Y; Wang, S; Zhang, H et al. iScience, DOI://10.1016/j.isci.2023.106301 (2023)
- Differential diagnosis of bone marrow failure syndromes guided by machine learning Gutierrez-Rodrigues, F; Munger, E; Ma, X et al. Blood, DOI://10.1182/blood.2022017518 (2023)
- Ultra-rare complement factor 8 coding variants in families with age-related macular degeneration Zelinger, L; Martin, TM; Advani, J et al. iScience, DOI://10.1016/j.isci.2023.106417 (2023)
- Parabolic avalanche scaling in the synchronization of cortical cell assemblies Capek, E; Ribeiro, TL; Kells, P et al. Nat Commun, DOI://10.1038/s41467-023-37976-x (2023)
- Detection of extensive host-virus DNA hybrids in human polyomavirus 7-associated pruritic rash Starrett, GJ; Lee, JW; Chatterjee, S; Jedrych, JJ; , Br J Dermatol, DOI://10.1093/bjd/ljad002 (2023)
- Improving Small Lesion Segmentation in CT Scans using Intensity Distribution Supervision: Application to Small Bowel Carcinoid Tumor Shin, SY; Shen, TC; Wank, SA; Summers, RM; , Proc SPIE Int Soc Opt Eng, DOI://10.1117/12.2651979 (2023)
- Staphylococcal diversity in atopic dermatitis from an individual to a global scale Saheb Kashaf, S; Harkins, CP; Deming, C et al. Cell Host Microbe, DOI://10.1016/j.chom.2023.03.010 (2023)
- Mutual Associations of Healthy Behaviours and Socioeconomic Status with Respiratory Diseases Mortality: A Large Prospective Cohort Study Du, M; Zhu, L; Liu, M; Liu, J; , Nutrients, DOI://10.3390/nu15081872 (2023)
- Evaluation of alcohol-free mouthwash for studies of the oral microbiome Yano, Y; Vogtmann, E; Shreves, AH et al. PLoS One, DOI://10.1371/journal.pone.0284956 (2023)
- Brain motion networks predict head motion during rest- and task-fMRI Tomasi, D; Volkow, ND; , Front Neurosci, DOI://10.3389/fnins.2023.1096232 (2023)
- Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness Li, Y; Lih, TM; Dhanasekaran, SM et al. Cancer Cell, DOI://10.1016/j.ccell.2022.12.001 (2023)
- XY sex determination in a cnidarian Chen, R; Sanders, SM; Ma, Z et al. BMC Biol, DOI://10.1186/s12915-023-01532-2 (2023)
- Oligodendrocyte-mediated myelin plasticity and its role in neural synchronization Pajevic, S; Plenz, D; Basser, PJ; Fields, RD; , Elife, DOI://10.7554/eLife.81982 (2023)
- ABCB1 and ABCG2 Overexpression Mediates Resistance to the Phosphatidylinositol 3-Kinase Inhibitor HS-173 in Cancer Cell Lines Wu, CP; Hung, CY; Hsieh, YJ et al. Cells, DOI://10.3390/cells12071056 (2023)
- Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes Pongor, LS; Schultz, CW; Rinaldi, L et al. Cancer Discov, DOI://10.1158/2159-8290.CD-22-0796 (2023)
- High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma Lang, M; Schmidt, LS; Wilson, KM et al. J Exp Clin Cancer Res, DOI://10.1186/s13046-023-02667-4 (2023)
- DIS3L2 ribonuclease degrades terminal-uridylated RNA to ensure oocyte maturation and female fertility Wu, D; Pedroza, M; Chang, J; Dean, J; , Nucleic Acids Res, DOI://10.1093/nar/gkad061 (2023)
- Whole organism profiling of the Timp gene family Peeney, D; Fan, Y; Gurung, S et al. Matrix Biol Plus, DOI://10.1016/j.mbplus.2023.100132 (2023)
- Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children Xu, Q; Milanez-Almeida, P; Martins, AJ et al. Nat Immunol, DOI://10.1038/s41590-022-01367-z (2023)
- Cryo-EM tomography and automatic segmentation delineate modular structures in the postsynaptic density Jung, JH; Chen, X; Reese, TS; , Front Synaptic Neurosci, DOI://10.3389/fnsyn.2023.1123564 (2023)
- Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusions Bogumil, H; Sill, M; Schrimpf, D et al. Acta Neuropathol, DOI://10.1007/s00401-023-02558-0 (2023)
- An influenza H1 hemagglutinin stem-only immunogen elicits a broadly cross-reactive B cell response in humans Andrews, SF; Cominsky, LY; Shimberg, GD et al. Sci Transl Med, DOI://10.1126/scitranslmed.ade4976 (2023)
- Bi-allelic SNAPC4 variants dysregulate global alternative splicing and lead to neuroregression and progressive spastic paraparesis Frost, FG; Morimoto, M; Sharma, P et al. Am J Hum Genet, DOI://10.1016/j.ajhg.2023.03.001 (2023)
- The art and science of using quality control to understand and improve fMRI data Teves, JB; Gonzalez-Castillo, J; Holness, M et al. Front Neurosci, DOI://10.3389/fnins.2023.1100544 (2023)
- Ophthalmic Manifestations of ROSAH (Retinal Dystrophy, Optic Nerve Edema, Splenomegaly, Anhidrosis, and Headache) Syndrome, an Inherited NF κB-Mediated Autoinflammatory Disease with Retinal Dystrophy Huryn, LA; Kozycki, CT; Serpen, JY et al. Ophthalmology, DOI://10.1016/j.ophtha.2022.10.026 (2023)
- Reserpine maintains photoreceptor survival in retinal ciliopathy by resolving proteostasis imbalance and ciliogenesis defects Chen, HY; Swaroop, M; Papal, S et al. Elife, DOI://10.7554/eLife.83205 (2023)
- A novel variant affecting the cytoplasmic tail of the FAT1 protocadherin causing coloboma and renal failure: A case report Vieta-Ferrer, ER; Ullah, E; Blain, D et al. Ophthalmic Genet, DOI://10.1080/13816810.2022.2089360 (2023)
- Circadian gene expression in mouse renal proximal tubule Bingham, MA; Neijman, K; Yang, CR et al. Am J Physiol Renal Physiol, DOI://10.1152/ajprenal.00231.2022 (2023)
- The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer Li, N; Quan, A; Li, D et al. Nat Commun, DOI://10.1038/s41467-023-37616-4 (2023)
- Cellular differentiation into hyphae and spores in halophilic archaea Tang, SK; Zhi, XY; Zhang, Y et al. Nat Commun, DOI://10.1038/s41467-023-37389-w (2023)
- Metagenomic characterization of the maternal prenatal gastrointestinal microbiome by pregravid BMI Dreisbach, C; Alhusen, J; Prescott, S et al. Obesity (Silver Spring), DOI://10.1002/oby.23659 (2023)
- Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome de Jesus, AA; Chen, G; Yang, D et al. Nat Commun, DOI://10.1038/s41467-023-36941-y (2023)
- Genetic sequencing of a 1944 Rocky Mountain spotted fever vaccine Xiao, Y; Beare, PA; Best, SM et al. Sci Rep, DOI://10.1038/s41598-023-31894-0 (2023)
- Specific recognition of an FGFR2 fusion by tumor infiltrating lymphocytes from a patient with metastatic cholangiocarcinoma White, BS; Sindiri, S; Hill, V et al. J Immunother Cancer, DOI://10.1136/jitc-2022-006303 (2023)
- SEQUIN is an R/Shiny framework for rapid and reproducible analysis of RNA-seq data Weber, C; Hirst, MB; Ernest, B et al. Cell Rep Methods, DOI://10.1016/j.crmeth.2023.100420 (2023)
- A novel framework for in-vivo diffusion tensor distribution MRI of the human brain Magdoom, KN; Avram, AV; Sarlls, JE et al. Neuroimage, DOI://10.1016/j.neuroimage.2023.120003 (2023)
- MYH2-associated myopathy caused by a novel splice-site variant Cassini, TA; Malicdan, MCV; Macnamara, EF et al. Neuromuscul Disord, DOI://10.1016/j.nmd.2022.12.014 (2023)
- mTOR inhibition overcomes RSK3-mediated resistance to BET inhibitors in small cell lung cancer Kumari, A; Gesumaria, L; Liu, YJ et al. JCI Insight, DOI://10.1172/jci.insight.156657 (2023)
- A conserved oligomerization domain in the disordered linker of coronavirus nucleocapsid proteins Zhao, H; Wu, D; Hassan, SA et al. Sci Adv, DOI://10.1126/sciadv.adg6473 (2023)
- Association of polygenic risk score with response to deep brain stimulation in Parkinson's disease Yoon, E; Ahmed, S; Li, R et al. BMC Neurol, DOI://10.1186/s12883-023-03188-5 (2023)
- Exaptation of Inactivated Host Enzymes for Structural Roles in Orthopoxviruses and Novel Folds of Virus Proteins Revealed by Protein Structure Modeling Mutz, P; Resch, W; Faure, G et al. mBio, DOI://10.1128/mbio.00408-23 (2023)
- Fully-automated detection of small bowel carcinoid tumors in CT scans using deep learning Shin, SY; Shen, TC; Wank, SA; Summers, RM; , Med Phys, DOI://10.1002/mp.16391 (2023)
- A Simple Method for Robust and Accurate Intrinsic Subtyping of Breast Cancer Hamaneh, M; Yu, YK; , Cancer Inform, DOI://10.1177/11769351231159893 (2023)
- Commercial influenza vaccines vary in HA-complex structure and in induction of cross-reactive HA antibodies Myers, ML; Gallagher, JR; Kim, AJ et al. Nat Commun, DOI://10.1038/s41467-023-37162-z (2023)
- Genome-wide contribution of common short-tandem repeats to Parkinson's disease genetic risk Bustos, BI; Billingsley, K; Blauwendraat, C et al. Brain, DOI://10.1093/brain/awac301 (2023)
- Bcs1, a novel target for fungicide Zhan, J; Xia, D; , Front Chem, DOI://10.3389/fchem.2023.1146753 (2023)
- Encoding of 3D physical dimensions by face-selective cortical neurons Khandhadia, AP; Murphy, AP; Koyano, KW et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2214996120 (2023)
- A cellular taxonomy of the adult human spinal cord Yadav, A; Matson, KJE; Li, L et al. Neuron, DOI://10.1016/j.neuron.2023.01.007 (2023)
- Pediatric-type high-grade neuroepithelial tumors with CIC gene fusion share a common DNA methylation signature Sievers, P; Sill, M; Schrimpf, D et al. NPJ Precis Oncol, DOI://10.1038/s41698-023-00372-1 (2023)
- Stochastic Modeling of Gene Expression Evolution Uncovers Tissue- and Sex-Specific Properties of Expression Evolution in the Drosophila Genus Pal, S; Oliver, B; Przytycka, TM; , J Comput Biol, DOI://10.1089/cmb.2022.0121 (2023)
- Neurotrophin signaling is a central mechanism of salivary dysfunction after irradiation that disrupts myoepithelial cells Chibly, AM; Patel, VN; Aure, MH et al. NPJ Regen Med, DOI://10.1038/s41536-023-00290-7 (2023)
- Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies Zhan, J; Lin, D; Watson, N et al. Cancer Res Commun, DOI://10.1158/2767-9764.CRC-22-0306 (2023)
- THINGS-data, a multimodal collection of large-scale datasets for investigating object representations in human brain and behavior Hebart, MN; Contier, O; Teichmann, L et al. Elife, DOI://10.7554/eLife.82580 (2023)
- The utility of a type 2 diabetes polygenic score in addition to clinical variables for prediction of type 2 diabetes incidence in birth, youth and adult cohorts in an Indigenous study population Wedekind, LE; Mahajan, A; Hsueh, WC et al. Diabetologia, DOI://10.1007/s00125-023-05870-2 (2023)
- Identification of GPI-anchored protein LYPD1 as an essential factor for odontoblast differentiation in tooth development Fu, Y; Miyazaki, K; Chiba, Y et al. J Biol Chem, DOI://10.1016/j.jbc.2023.104638 (2023)
- A dataset for medical instructional video classification and question answering Gupta, D; Attal, K; Demner-Fushman, D; , Sci Data, DOI://10.1038/s41597-023-02036-y (2023)
- The Foundational Data Initiative for Parkinson Disease: Enabling efficient translation from genetic maps to mechanism Bressan, E; Reed, X; Bansal, V et al. Cell Genom, DOI://10.1016/j.xgen.2023.100261 (2023)
- Progressive neuronal plasticity in primate visual cortex during stimulus familiarization Koyano, KW; Esch, EM; Hong, JJ et al. Sci Adv, DOI://10.1126/sciadv.ade4648 (2023)
- Genetic subgroups inform on pathobiology in adult and pediatric Burkitt lymphoma Thomas, N; Dreval, K; Gerhard, DS et al. Blood, DOI://10.1182/blood.2022016534 (2023)
- A deeper insight into the sialome of male and female Culex quinquefasciatus mosquitoes Lu, S; Martin-Martin, I; Ribeiro, JM; Calvo, E; , BMC Genomics, DOI://10.1186/s12864-023-09236-1 (2023)
- Clinically oriented prediction of patient response to targeted and immunotherapies from the tumor transcriptome Dinstag, G; Shulman, ED; Elis, E et al. Med, DOI://10.1016/j.medj.2022.11.001 (2023)
- A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism Andersen, JF; Lei, H; Strayer, EC et al. Blood, DOI://10.1182/blood.2022019359 (2023)
- Wastewater surveillance uncovers regional diversity and dynamics of SARS-CoV-2 variants across nine states in the USA Fontenele, RS; Yang, Y; Driver, EM et al. Sci Total Environ, DOI://10.1016/j.scitotenv.2023.162862 (2023)
- Antipsychotic drug use complicates assessment of gene expression changes associated with schizophrenia Schulmann, A; Marenco, S; Vawter, MP et al. Transl Psychiatry, DOI://10.1038/s41398-023-02392-8 (2023)
- Additive Effects of Stress and Alcohol Exposure on Accelerated Epigenetic Aging in Alcohol Use Disorder Jung, J; McCartney, DL; Wagner, J et al. Biol Psychiatry, DOI://10.1016/j.biopsych.2022.06.036 (2023)
- Human VH-based chimeric antigen receptor T cells targeting glypican 3 eliminate tumors in preclinical models of HCC Kolluri, A; Li, D; Li, N et al. Hepatol Commun, DOI://10.1097/HC9.0000000000000022 (2023)
- IntLIM 2.0: identifying multi-omic relationships dependent on discrete or continuous phenotypic measurements Eicher, T; Spencer, KD; Siddiqui, JK et al. Bioinform Adv, DOI://10.1093/bioadv/vbad009 (2023)
- Two distinct long-range synaptic complexes promote different aspects of end processing prior to repair of DNA breaks by non-homologous end joining Buehl, CJ; Goff, NJ; Hardwick, SW et al. Mol Cell, DOI://10.1016/j.molcel.2023.01.012 (2023)
- Activation mechanisms of clinically distinct B-Raf V600E and V600K mutants Zhang, M; Maloney, R; Liu, Y et al. Cancer Commun (Lond), DOI://10.1002/cac2.12395 (2023)
- Strategy toward Kinase-Selective Drug Discovery Zhang, M; Liu, Y; Jang, H; Nussinov, R; , J Chem Theory Comput, DOI://10.1021/acs.jctc.2c01171 (2023)
- A Cross-Species Neuroimaging Study of Sex Chromosome Dosage Effects on Human and Mouse Brain Anatomy Guma, E; Beauchamp, A; Liu, S et al. J Neurosci, DOI://10.1523/JNEUROSCI.1761-22.2022 (2023)
- Structures of brain-derived 42-residue amyloid-β fibril polymorphs with unusual molecular conformations and intermolecular interactions Lee, M; Yau, WM; Louis, JM; Tycko, R; , Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2218831120 (2023)
- miRNA Expression Profiles of Mouse Round Spermatids in GRTH/DDX25-Mediated Spermiogenesis: mRNA-miRNA Network Analysis Anbazhagan, R; Kavarthapu, R; Dale, R et al. Cells, DOI://10.3390/cells12050756 (2023)
- Enhancer-promoter interactions can bypass CTCF-mediated boundaries and contribute to phenotypic robustness Chakraborty, S; Kopitchinski, N; Zuo, Z et al. Nat Genet, DOI://10.1038/s41588-022-01295-6 (2023)
- Machine Learning Informs RNA-Binding Chemical Space Yazdani, K; Jordan, D; Yang, M et al. Angew Chem Int Ed Engl, DOI://10.1002/anie.202211358 (2023)
- Visualizing RNA conformational and architectural heterogeneity in solution Ding, J; Lee, YT; Bhandari, Y et al. Nat Commun, DOI://10.1038/s41467-023-36184-x (2023)
- HIV vaccine candidate efficacy in female macaques mediated by cAMP-dependent efferocytosis and V2-specific ADCC Bissa, M; Kim, S; Galli, V et al. Nat Commun, DOI://10.1038/s41467-023-36109-8 (2023)
- Stylized versus voxel phantoms: quantification of internal organ chord length distances Coleman, D; Griffin, KT; Dewji, SA; , Phys Med Biol, DOI://10.1088/1361-6560/acbbb6 (2023)
- Molecular classification and grading of meningioma Nasrallah, MP; Aldape, KD; , J Neurooncol, DOI://10.1007/s11060-022-04228-9 (2023)
- Biglycan regulates bone development and regeneration Shainer, R; Kram, V; Kilts, TM et al. Front Physiol, DOI://10.3389/fphys.2023.1119368 (2023)
- The dogs of Chernobyl: Demographic insights into populations inhabiting the nuclear exclusion zone Spatola, GJ; Buckley, RM; Dillon, M et al. Sci Adv, DOI://10.1126/sciadv.ade2537 (2023)
- Transcription factor TFII-I fine tunes innate properties of B lymphocytes Singh, A; Kaileh, M; De, S et al. Front Immunol, DOI://10.3389/fimmu.2023.1067459 (2023)
- Altered gene expression in excitatory neurons is associated with Alzheimer's disease and its higher incidence in women Garcia, AX; Xu, J; Cheng, F et al. Alzheimers Dement (N Y), DOI://10.1002/trc2.12373 (2023)
- State-specific morphological deformations of the lipid bilayer explain mechanosensitive gating of MscS ion channels Park, YC; Reddy, B; Bavi, N et al. Elife, DOI://10.7554/eLife.81445 (2023)
- Synthetic analysis of chromatin tracing and live-cell imaging indicates pervasive spatial coupling between genes Bohrer, CH; Larson, DR; , Elife, DOI://10.7554/eLife.81861 (2023)
- Murine allogeneic CAR T cells integrated before or early after posttransplant cyclophosphamide exert antitumor effects Patterson, MT; Khan, SM; Nunes, NS et al. Blood, DOI://10.1182/blood.2022016660 (2023)
- Cohesin regulates alternative splicing Singh, AK; Chen, Q; Nguyen, C et al. Sci Adv, DOI://10.1126/sciadv.ade3876 (2023)
- Differential requirements for Gcn5 and NuA4 HAT activities in the starvation-induced versus basal transcriptomes Zheng, Q; Qiu, H; Zhang, H; Hinnebusch, AG; , Nucleic Acids Res, DOI://10.1093/nar/gkad099 (2023)
- HAND2 Assists MYCN Enhancer Invasion to Regulate a Noradrenergic Neuroblastoma Phenotype Xu, M; Sun, M; Zhang, X et al. Cancer Res, DOI://10.1158/0008-5472.CAN-22-2042 (2023)
- Genomic and transcriptomic analyses identify a prognostic gene signature and predict response to therapy in pleural and peritoneal mesothelioma Nair, NU; Jiang, Q; Wei, JS et al. Cell Rep Med, DOI://10.1016/j.xcrm.2023.100938 (2023)
- Specific targeting of inflammatory osteoclastogenesis by the probiotic yeast S. boulardii CNCM I-745 reduces bone loss in osteoporosis Madel, MB; Halper, J; Ibáñez, L et al. Elife, DOI://10.7554/eLife.82037 (2023)
- Binding preference at the μ-opioid receptor underlies distinct pharmacology of cyclopropyl versus valeryl analogs of fentanyl Xie, B; Le Rouzic, VP; Goldberg, A et al. Neuropharmacology, DOI://10.1016/j.neuropharm.2023.109442 (2023)
- Tumor necroptosis-mediated shedding of cell surface proteins promotes metastasis of breast cancer by suppressing anti-tumor immunity Liu, Z; Choksi, S; Kwon, HJ et al. Breast Cancer Res, DOI://10.1186/s13058-023-01604-9 (2023)
- Identification of SARS-CoV-2 Mpro inhibitors containing P1 4-fluorobenzothiazole moiety highly active against SARS-CoV-2 Higashi-Kuwata, N; Tsuji, K; Hayashi, H et al. Nat Commun, DOI://10.1038/s41467-023-36729-0 (2023)
- Protocol for comparing gene-level selection on coding mutations between two groups of samples with Coselens Iranzo, J; Gruenhagen, G; Calle-Espinosa, J; Koonin, EV; , STAR Protoc, DOI://10.1016/j.xpro.2023.102117 (2023)
- Rickettsia parkeri hijacks tick hemocytes to manipulate cellular and humoral transcriptional responses Adegoke, A; Ribeiro, JMC; Brown, S et al. Front Immunol, DOI://10.3389/fimmu.2023.1094326 (2023)
- A highly replicable decline in mood during rest and simple tasks Jangraw, DC; Keren, H; Sun, H et al. Nat Hum Behav, DOI://10.1038/s41562-023-01519-7 (2023)
- Mining metatranscriptomes reveals a vast world of viroid-like circular RNAs Lee, BD; Neri, U; Roux, S et al. Cell, DOI://10.1016/j.cell.2022.12.039 (2023)
- Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD Chen, Y; Prévost, J; Ullah, I et al. iScience, DOI://10.1016/j.isci.2022.105783 (2023)
- Discovery of clinical and demographic determinants of symptom burden in primary brain tumor patients using network analysis and unsupervised clustering Bergsneider, BH; Vera, E; Gal, O et al. Neurooncol Adv, DOI://10.1093/noajnl/vdac188 (2023)
- E6AP AZUL interaction with UBQLN1/2 in cells, condensates, and an AlphaFold-NMR integrated structure Buel, GR; Chen, X; Myint, W et al. Structure, DOI://10.1016/j.str.2023.01.012 (2023)
- The NLM indexer assignment dataset: a new large-scale dataset for reviewer assignment research Rae, AR; Mork, JG; Demner-Fushman, D; , J Assoc Inf Sci Technol, DOI://10.1002/asi.24722 (2023)
- Fear-potentiated startle reveals diminished threat extinction in pathological anxiety Newsome, P; Ruiz, SG; Gold, AL et al. Int J Psychophysiol, DOI://10.1016/j.ijpsycho.2022.11.011 (2023)
- Measures of Brain Connectivity and Cognition by Sex in US Children Tomasi, D; Volkow, ND; , JAMA Netw Open, DOI://10.1001/jamanetworkopen.2023.0157 (2023)
- Longitudinal multi-omics analyses of the gut-liver axis reveals metabolic dysregulation in hepatitis C infection and cirrhosis Ali, RO; Quinn, GM; Umarova, R et al. Nat Microbiol, DOI://10.1038/s41564-022-01273-y (2023)
- Identification and characterization of the long non-coding RNA NFIA-AS2 as a novel locus for body mass index in American Indians Bandesh, K; Traurig, M; Chen, P et al. Int J Obes (Lond), DOI://10.1038/s41366-023-01278-5 (2023)
- Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency Zhang, B; Gorman, J; Kwon, YD et al. MAbs, DOI://10.1080/19420862.2023.2165390 (2023)
- A de novo hexokinase 1 (HK1) variant presenting as Boucher-Neuhäuser syndrome Peretz, RH; Zein, WM; Hufnagel, RB et al. Am J Med Genet A, DOI://10.1002/ajmg.a.63045 (2023)
- Autophagy Requirements for Eye Lens Differentiation and Transparency Brennan, L; Costello, MJ; Hejtmancik, JF et al. Cells, DOI://10.3390/cells12030475 (2023)
- De novo human brain enhancers created by single-nucleotide mutations Li, S; Hannenhalli, S; Ovcharenko, I; , Sci Adv, DOI://10.1126/sciadv.add2911 (2023)
- Role of ultra-high b-value DWI in the imaging of hereditary leiomyomatosis and renal cell carcinoma (HLRCC) Chaurasia, A; Gopal, N; Dehghani Firouzabadi, F et al. Abdom Radiol (NY), DOI://10.1007/s00261-022-03689-w (2023)
- A dual-activity topoisomerase complex promotes both transcriptional activation and repression in response to starvation Su, S; Xue, Y; Lee, SK et al. Nucleic Acids Res, DOI://10.1093/nar/gkad086 (2023)
- Telomere-to-telomere assembly of diploid chromosomes with Verkko Rautiainen, M; Nurk, S; Walenz, BP et al. Nat Biotechnol, DOI://10.1038/s41587-023-01662-6 (2023)
- A 64-year-old woman with frontal lobe lesion and drug-resistant epilepsy Jin, X; Abdullaev, Z; Butman, JA et al. Brain Pathol, DOI://10.1111/bpa.13133 (2023)
- Intrinsically dysregulated cellular stress signaling genes and gene networks in postpartum depression Rudzinskas, SA; Goff, AC; Mazzu, MA et al. Mol Psychiatry, DOI://10.1038/s41380-023-01985-5 (2023)
- Bi-allelic ATG4D variants are associated with a neurodevelopmental disorder characterized by speech and motor impairment Morimoto, M; Bhambhani, V; Gazzaz, N et al. NPJ Genom Med, DOI://10.1038/s41525-022-00343-8 (2023)
- MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain Becht, DC; Klein, BJ; Kanai, A et al. Nat Commun, DOI://10.1038/s41467-023-36368-5 (2023)
- Pleural fluid microbiota as a biomarker for malignancy and prognosis Kwok, B; Wu, BG; Kocak, IF et al. Sci Rep, DOI://10.1038/s41598-023-29001-4 (2023)
- CD47-Dependent Regulation of Immune Checkpoint Gene Expression and MYCN mRNA Splicing in Murine CD8 and Jurkat T Cells Kaur, S; Awad, D; Finney, RP et al. Int J Mol Sci, DOI://10.3390/ijms24032612 (2023)
- Deep Domain Adversarial Learning for Species-Agnostic Classification of Histologic Subtypes of Osteosarcoma Patkar, S; Beck, J; Harmon, S et al. Am J Pathol, DOI://10.1016/j.ajpath.2022.09.009 (2023)
- Analysis of immune responses in CLL patients after heterologous COVID-19 vaccination Lee, HK; Hoechstetter, MA; Buchner, M et al. Blood Adv, DOI://10.1182/bloodadvances.2022008445 (2023)
- Organ-specific effects on target binding due to knockout of thyroid hormone receptor α during Xenopus metamorphosis Tanizaki, Y; Zhang, H; Shibata, Y; Shi, YB; , Dev Growth Differ, DOI://10.1111/dgd.12825 (2023)
- Racial/Ethnic Differences in Associations Between Traumatic Childhood Experiences and Both Metabolic Syndrome Prevalence and Type 2 Diabetes Risk Among a Cohort of U.S. Women Gaston, SA; Riley, NM; Parks, CG et al. Diabetes Care, DOI://10.2337/dc22-1486 (2023)
- Transcription factors underlying photoreceptor diversity Angueyra, JM; Kunze, VP; Patak, LK et al. Elife, DOI://10.7554/eLife.81579 (2023)
- Heterogeneous clinicopathological findings and patient-reported outcomes in adults with MN1-altered CNS tumors: A case report and systematic literature review Frederico, SC; Vera, E; Abdullaev, Z et al. Front Oncol, DOI://10.3389/fonc.2023.1099618 (2023)
- Oral microbiome and risk of incident head and neck cancer: A nested case-control study Wu, Z; Han, Y; Wan, Y et al. Oral Oncol, DOI://10.1016/j.oraloncology.2022.106305 (2023)
- Direct Cryo-ET observation of platelet deformation induced by SARS-CoV-2 spike protein Kuhn, CC; Basnet, N; Bodakuntla, S et al. Nat Commun, DOI://10.1038/s41467-023-36279-5 (2023)
- Estimation of cell lineages in tumors from spatial transcriptomics data Ru, B; Huang, J; Zhang, Y et al. Nat Commun, DOI://10.1038/s41467-023-36062-6 (2023)
- Genotype first: Clinical genomics research through a reverse phenotyping approach Wilczewski, CM; Obasohan, J; Paschall, JE et al. Am J Hum Genet, DOI://10.1016/j.ajhg.2022.12.004 (2023)
- Author Correction: Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes Lehman, NL; Spassky, N; Sak, M et al. Nat Commun, DOI://10.1038/s41467-023-36255-z (2023)
- Identification of cerebral spinal fluid protein biomarkers in Niemann-Pick disease, type C1 Campbell, K; Cawley, NX; Luke, R et al. Biomark Res, DOI://10.1186/s40364-023-00448-x (2023)
- Expanded NK cells used for adoptive cell therapy maintain diverse clonality and contain long-lived memory-like NK cell populations Allan, DSJ; Wu, C; Mortlock, RD et al. Mol Ther Oncolytics, DOI://10.1016/j.omto.2022.12.006 (2023)
- Spleen tyrosine kinase inhibition restores myeloid homeostasis in COVID-19 Wigerblad, G; Warner, SA; Ramos-Benitez, MJ et al. Sci Adv, DOI://10.1126/sciadv.ade8272 (2023)
- Genetic Influences on Fetal Alcohol Spectrum Disorder Sambo, D; Goldman, D; , Genes (Basel), DOI://10.3390/genes14010195 (2023)
- Chromatin landscape governing murine epidermal differentiation Nayak, S; Jiang, K; Hope, E et al. J Invest Dermatol, DOI://10.1016/j.jid.2022.12.020 (2023)
- Inflated expectations: Rare-variant association analysis using public controls Kim, J; Karyadi, DM; Hartley, SW et al. PLoS One, DOI://10.1371/journal.pone.0280951 (2023)
- Middle-age high normal serum sodium as a risk factor for accelerated biological aging, chronic diseases, and premature mortality Dmitrieva, NI; Gagarin, A; Liu, D et al. EBioMedicine, DOI://10.1016/j.ebiom.2022.104404 (2023)
- Expression and subcellular localization of USH1C/harmonin in human retina provides insights into pathomechanisms and therapy Nagel-Wolfrum, K; Fadl, BR; Becker, MM et al. Hum Mol Genet, DOI://10.1093/hmg/ddac211 (2023)
- Revisiting the sialome of the cat flea Ctenocephalides felis Lu, S; Danchenko, M; Macaluso, KR; Ribeiro, JMC; , PLoS One, DOI://10.1371/journal.pone.0279070 (2023)
- Upper age-limits for US male HPV-vaccination for oropharyngeal cancer prevention: A microsimulation-based modeling study Landy, R; Haber, G; Graubard, BI et al. J Natl Cancer Inst, DOI://10.1093/jnci/djad009 (2023)
- GWAS Explorer: an open-source tool to explore, visualize, and access GWAS summary statistics in the PLCO Atlas Machiela, MJ; Huang, WY; Wong, W et al. Sci Data, DOI://10.1038/s41597-022-01921-2 (2023)
- Transcriptomic Analysis of Human Podocytes In Vitro: Effects of Differentiation and APOL1 Genotype Yoshida, T; Latt, KZ; Rosenberg, AZ et al. Kidney Int Rep, DOI://10.1016/j.ekir.2022.10.011 (2023)
- The repertoire of CSF antiviral antibodies in patients with neuroinflammatory diseases Enose-Akahata, Y; Wang, L; Almsned, F et al. Sci Adv, DOI://10.1126/sciadv.abq6978 (2023)
- Preclinical optimization of a GPC2-targeting CAR T-cell therapy for neuroblastoma Sun, M; Cao, Y; Okada, R et al. J Immunother Cancer, DOI://10.1136/jitc-2022-005881 (2023)
- Characterization of diverse populations of sinoatrial node cells and their proliferation potential at single nucleus resolution Qu, JH; Telljohann, R; Byshkov, R; Lakatta, EG; , Heliyon, DOI://10.1016/j.heliyon.2022.e12708 (2023)
- The Ewald sphere/focus gradient does not limit the resolution of cryoEM reconstructions Heymann, JB J Struct Biol X, DOI://10.1016/j.yjsbx.2022.100083 (2023)
- Novel polyomaviruses identified in fecal samples from four carnivore species Kraberger, S; Serieys, LEK; Riley, SPD et al. Arch Virol, DOI://10.1007/s00705-022-05675-5 (2023)
- Comparison of busulfan and total body irradiation conditioning on hematopoietic clonal dynamics following lentiviral gene transfer in rhesus macaques Abraham, DM; Lozano, RJ; Guitart, X et al. Mol Ther Methods Clin Dev, DOI://10.1016/j.omtm.2022.12.001 (2023)
- Prenatal social support in low-risk pregnancy shapes placental epigenome Tesfaye, M; Wu, J; Biedrzycki, RJ et al. BMC Med, DOI://10.1186/s12916-022-02701-w (2023)
- Epigenetic gestational age and the relationship with developmental milestones in early childhood Polinski, KJ; Robinson, SL; Putnick, DL et al. Hum Mol Genet, DOI://10.1093/hmg/ddac302 (2023)
- A dataset for plain language adaptation of biomedical abstracts Attal, K; Ondov, B; Demner-Fushman, D; , Sci Data, DOI://10.1038/s41597-022-01920-3 (2023)
- A stem cell epigenome is associated with primary nonresponse to CD19 CAR T-cells in pediatric acute lymphoblastic leukemia Masih, KE; Gardner, RA; Chou, HC et al. Blood Adv, DOI://10.1182/bloodadvances.2022008977 (2023)
- Variable selection for discrete survival model with frailty in presence of left truncation and right censoring: Studying association of environmental toxicants on time-to-pregnancy Saha, A; Sundaram, R; , Stat Med, DOI://10.1002/sim.9609 (2023)
- Investigating Determinants and Evaluating Deep Learning Training Approaches for Visual Acuity in Foveal Hypoplasia Malechka, VV; Duong, D; Bordonada, KD et al. Ophthalmol Sci, DOI://10.1016/j.xops.2022.100225 (2023)
- An inducible amphipathic α-helix mediates subcellular targeting and membrane binding of RPE65 Uppal, S; Liu, T; Galvan, E et al. Life Sci Alliance, DOI://10.26508/lsa.202201546 (2023)
- Mix-and-Inject Serial Femtosecond Crystallography to Capture RNA Riboswitch Intermediates Stagno, JR; Knoska, J; Chapman, HN; Wang, YX; , Methods Mol Biol, DOI://10.1007/978-1-0716-2687-0_16 (2023)
- Combining Biophysical Methods for Structure-Function Analyses of RNA in Solution Lee, YT; Fan, L; Ding, J; Wang, YX; , Methods Mol Biol, DOI://10.1007/978-1-0716-2687-0_11 (2023)
- Application of Molecular Dynamics to Expand Docking Program's Exploratory Capabilities and to Evaluate Its Predictions Kasprzak, WK; Shapiro, BA; , Methods Mol Biol, DOI://10.1007/978-1-0716-2687-0_6 (2023)
2022 (618 papers)
- Circulating microRNAs in cellular and antibody-mediated heart transplant rejection Shah, P; Agbor-Enoh, S; Bagchi, P et al. J Heart Lung Transplant, DOI://10.1016/j.healun.2022.06.019 (2022)
- Visual Field Sensitivity Prediction Using Optical Coherence Tomography Analysis in Hydroxychloroquine Toxicity Jayakar, G; De Silva, T; Cukras, CA; , Invest Ophthalmol Vis Sci, DOI://10.1167/iovs.63.1.15 (2022)
- Fast intratumor heterogeneity inference from single-cell sequencing data Kızılkale, C; Rashidi Mehrabadi, F; Sadeqi Azer, E et al. Nat Comput Sci, DOI://10.1038/s43588-022-00298-x (2022)
- A reference human induced pluripotent stem cell line for large-scale collaborative studies Pantazis, CB; Yang, A; Lara, E et al. Cell Stem Cell, DOI://10.1016/j.stem.2022.11.004 (2022)
- Blocking CDK7-Mediated NOTCH1-cMYC Signaling Attenuates Cancer Stem Cell Activity in Anaplastic Thyroid Cancer Doolittle, WKL; Zhao, L; Cheng, SY; , Thyroid, DOI://10.1089/thy.2022.0087 (2022)
- Opioid medication use and blood DNA methylation: epigenome-wide association meta-analysis Lee, M; Joehanes, R; McCartney, DL et al. Epigenomics, DOI://10.2217/epi-2022-0353 (2022)
- Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade Palmer, DC; Webber, BR; Patel, Y et al. Med, DOI://10.1016/j.medj.2022.07.008 (2022)
- Automated Assessment of Renal Calculi in Serial Computed Tomography Scans Mukherjee, P; Lee, S; Pickhardt, PJ; Summers, RM; , Appl Med Artif Intell (2022), DOI://10.1007/978-3-031-17721-7_5 (2022)
- Protein pKa Prediction by Tree-Based Machine Learning Chen, AY; Lee, J; Damjanovic, A; Brooks, BR; , J Chem Theory Comput, DOI://10.1021/acs.jctc.1c01257 (2022)
- Noninvasive biomarkers in heart transplant: 2020-2021 year in review Qian, X; Shah, P; Agbor-Enoh, S; , Curr Opin Organ Transplant, DOI://10.1097/MOT.0000000000000945 (2022)
- Metformin treatment rescues CD8+ T-cell response to immune checkpoint inhibitor therapy in mice with NAFLD Wabitsch, S; McCallen, JD; Kamenyeva, O et al. J Hepatol, DOI://10.1016/j.jhep.2022.03.010 (2022)
- Magnetoencephalography biomarkers of suicide attempt history and antidepressant response to ketamine in treatment-resistant major depression Gilbert, JR; Gerner, JL; Burton, CR et al. J Affect Disord, DOI://10.1016/j.jad.2022.06.025 (2022)
- Cardiovascular disease and all-cause mortality risk prediction from abdominal CT using deep learning Daniel C. Elton, Andy Chen, Perry J. Pickhardt, Ronald M. Summers Medical Imaging 2022, doi://10.1117/12.2612620 (2022)
- Potential therapeutic response in a severe case of autosomal dominant osteopetrosis type I Jafri SM; Burke EA; et al . J Transl Genet Genom, doi://10.20517/jtgg.2021.63 (2022)
- Molecular Genetic Analysis of Ukrainian Families with Congenital Cataracts Jiao, X; Viswanathan, M; Bobrova, NF et al. Children (Basel), DOI://10.3390/children10010051 (2022)
- Heterogeneity of enhancers embodies shared and representative functional groups underlying developmental and cell type-specific gene regulation Song, W; Ovcharenko, I; , Gene, DOI://10.1016/j.gene.2022.146640 (2022)
- High-Throughput DNA FISH (hiFISH) Finn, E; Misteli, T; Pegoraro, G; , Methods Mol Biol, DOI://10.1007/978-1-0716-2497-5_12 (2022)
- Middle age serum sodium levels in the upper part of normal range and risk of heart failure Dmitrieva, NI; Liu, D; Wu, CO; Boehm, M; , Eur Heart J, DOI://10.1093/eurheartj/ehac138 (2022)
- Histone deacetylation primes self-propagation of heterochromatin domains to promote epigenetic inheritance Zofall, M; Sandhu, R; Holla, S et al. Nat Struct Mol Biol, DOI://10.1038/s41594-022-00830-7 (2022)
- Long-term antibiotic exposure promotes mortality after systemic fungal infection by driving lymphocyte dysfunction and systemic escape of commensal bacteria Drummond, RA; Desai, JV; Ricotta, EE et al. Cell Host Microbe, DOI://10.1016/j.chom.2022.04.013 (2022)
- Cytomegalovirus infection reduced CD70 expression, signaling and expansion of viral specific memory CD8+ T cells in healthy human adults Lu, J; Chen, G; Sorokina, A et al. Immun Ageing, DOI://10.1186/s12979-022-00307-7 (2022)
- Multistate models for the natural history of cancer progression Cheung, LC; Albert, PS; Das, S; Cook, RJ; , Br J Cancer, DOI://10.1038/s41416-022-01904-5 (2022)
- PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program Hashimoto, M; Araki, K; Cardenas, MA et al. Nature, DOI://10.1038/s41586-022-05257-0 (2022)
- Higher levels of allograft injury in black patients early after heart transplantation Doshi, A; Shah, KB; Agbor-Enoh, S et al. J Heart Lung Transplant, DOI://10.1016/j.healun.2021.12.006 (2022)
- Functional aspects of evolution in a cluster of salivary protein genes from mosquitoes Alvarenga, PH; Dias, DR; Xu, X et al. Insect Biochem Mol Biol, DOI://10.1016/j.ibmb.2022.103785 (2022)
- Developmental genome-wide occupancy analysis of bZIP transcription factor NRL uncovers the role of c-Jun in early differentiation of rod photoreceptors in the mammalian retina Liang, X; Brooks, MJ; Swaroop, A; , Hum Mol Genet, DOI://10.1093/hmg/ddac143 (2022)
- Recreational physical activity before and during pregnancy and placental DNA methylation-an epigenome-wide association study Zhao, SK; Yeung, EH; Ouidir, M et al. Am J Clin Nutr, DOI://10.1093/ajcn/nqac111 (2022)
- Hierarchical Voting-Based Feature Selection and Ensemble Learning Model Scheme for Glioma Grading with Clinical and Molecular Characteristics Tasci, E; Zhuge, Y; Kaur, H et al. Int J Mol Sci, DOI://10.3390/ijms232214155 (2022)
- Identification of a novel GR-ARID1a-P53BP1 protein complex involved in DNA damage repair and cell cycle regulation Stubbs, FE; Flynn, BP; Rivers, CA et al. Oncogene, DOI://10.1038/s41388-022-02516-2 (2022)
- Defining cellular population dynamics at single-cell resolution during prostate cancer progression Germanos, AA; Arora, S; Zheng, Y et al. Elife, DOI://10.7554/eLife.79076 (2022)
- Logistic Regression-Based Model Is More Efficient Than U-Net Model for Reliable Whole Brain Magnetic Resonance Imaging Segmentation Dieckhaus, H; Meijboom, R; Okar, S et al. Top Magn Reson Imaging, DOI://10.1097/RMR.0000000000000296 (2022)
- Mendelian randomization study reveals a causal relationship between adiponectin and LDL cholesterol in Africans Meeks, KAC; Bentley, AR; Doumatey, AP et al. Sci Rep, DOI://10.1038/s41598-022-21922-w (2022)
- Baseline Microperimetry and OCT in the RUSH2A Study: Structure-Function Association and Correlation With Disease Severity Lad, EM; Duncan, JL; Liang, W et al. Am J Ophthalmol, DOI://10.1016/j.ajo.2022.08.013 (2022)
- Rare germline deleterious variants increase susceptibility for lung cancer Sang, J; Zhang, T; Kim, J et al. Hum Mol Genet, DOI://10.1093/hmg/ddac123 (2022)
- Nucleation causes an actin network to fragment into multiple high-density domains Chandrasekaran, A; Giniger, E; Papoian, GA; , Biophys J, DOI://10.1016/j.bpj.2022.07.035 (2022)
- fast.adonis: a computationally efficient non-parametric multivariate analysis of microbiome data for large-scale studies Li, S; Vogtmann, E; Graubard, BI et al. Bioinform Adv, DOI://10.1093/bioadv/vbac044 (2022)
- Early-Onset TIMP3-Related Retinopathy Associated With Impaired Signal Peptide Guan, B; Huryn, LA; Hughes, AB et al. JAMA Ophthalmol, DOI://10.1001/jamaophthalmol.2022.1822 (2022)
- Cell-free DNA in lung transplantation: research tool or clinical workhorse? Keller, M; Agbor-Enoh, S; , Curr Opin Organ Transplant, DOI://10.1097/MOT.0000000000000979 (2022)
- Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities Karz, A; Dimitrova, M; Kleffman, K et al. Pigment Cell Melanoma Res, DOI://10.1111/pcmr.13059 (2022)
- Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation Jiang, J; Taylor, DK; Kim, EJ et al. Nat Commun, DOI://10.1038/s41467-022-33153-8 (2022)
- Lysine methyltransferase Kmt2d regulates naive CD8+ T cell activation-induced survival Kim, J; Nguyen, T; Cifello, J et al. Front Immunol, DOI://10.3389/fimmu.2022.1095140 (2022)
- Gene-Level Associations in Patients With and Without Pathogenic Germline Variants in CDKN2A and Pancreatic Cancer Astiazaran-Symonds, E; Graham, C; Kim, J et al. JCO Precis Oncol, DOI://10.1200/PO.22.00145 (2022)
- Context-Dependent Function of Long Noncoding RNA PURPL in Transcriptome Regulation during p53 Activation Hartford, CCR; Shrestha, RL; Pongor, L et al. Mol Cell Biol, DOI://10.1128/mcb.00289-22 (2022)
- Zfp503/Nlz2 Is Required for RPE Differentiation and Optic Fissure Closure Boobalan, E; Thompson, AH; Alur, RP et al. Invest Ophthalmol Vis Sci, DOI://10.1167/iovs.63.12.5 (2022)
- A Graph-theoretic Algorithm for Small Bowel Path Tracking in CT Scans Shin, SY; Lee, S; Summers, RM; , Proc SPIE Int Soc Opt Eng, DOI://10.1117/12.2611878 (2022)
- GRAPH-BASED SMALL BOWEL PATH TRACKING WITH CYLINDRICAL CONSTRAINTS Shin, SY; Lee, S; Summers, RM; , Proc IEEE Int Symp Biomed Imaging, DOI://10.1109/isbi52829.2022.9761423 (2022)
- Deep Reinforcement Learning for Small Bowel Path Tracking using Different Types of Annotations Shin, SY; Summers, RM; , Med Image Comput Comput Assist Interv, DOI://10.1007/978-3-031-16443-9_53 (2022)
- Identifying and predicting amyotrophic lateral sclerosis clinical subgroups: a population-based machine-learning study Faghri, F; Brunn, F; Dadu, A et al. Lancet Digit Health, DOI://10.1016/S2589-7500(21)00274-0 (2022)
- An MRI-based radiomics model to predict clear cell renal cell carcinoma growth rate classes in patients with von Hippel-Lindau syndrome Anari, PY; Lay, N; Gopal, N et al. Abdom Radiol (NY), DOI://10.1007/s00261-022-03610-5 (2022)
- Topoisomerase 3b is dispensable for replication of a positive-sense RNA virus--murine coronavirus Zhang, T; Su, S; Altouma, V et al. Antiviral Res, DOI://10.1016/j.antiviral.2022.105451 (2022)
- Genetic Origins of the Two Canis lupus familiaris (Dog) Freight Dog Populations Ali, MB; Dreger, DL; Buckley, RM et al. J Hered, DOI://10.1093/jhered/esac002 (2022)
- Differential regulation of transcription factor T-bet induction during NK cell development and T helper-1 cell differentiation Fang, D; Cui, K; Cao, Y et al. Immunity, DOI://10.1016/j.immuni.2022.03.005 (2022)
- ImmunoTyper-SR: A computational approach for genotyping immunoglobulin heavy chain variable genes using short-read data Ford, MKB; Hari, A; Rodriguez, O et al. Cell Syst, DOI://10.1016/j.cels.2022.08.008 (2022)
- Alcohol use disorder is associated with DNA methylation-based shortening of telomere length and regulated by TESPA1: implications for aging Jung, J; McCartney, DL; Wagner, J et al. Mol Psychiatry, DOI://10.1038/s41380-022-01624-5 (2022)
- Discriminatory capacity of prenatal ultrasound measures for large-for-gestational-age birth: A Bayesian approach to ROC analysis using placement values Ghosal, S; Chen, Z; , Stat Biosci, DOI://10.1007/s12561-021-09311-9 (2022)
- Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding Doyle, MT; Jimah, JR; Dowdy, T et al. Cell, DOI://10.1016/j.cell.2022.02.016 (2022)
- Daily changes in light influence mood via inhibitory networks within the thalamic perihabenular nucleus Weil, T; Daly, KM; Yarur Castillo, H et al. Sci Adv, DOI://10.1126/sciadv.abn3567 (2022)
- Monoallelic variants resulting in substitutions of MAB21L1 Arg51 Cause Aniridia and microphthalmia Hall, HN; Bengani, H; Hufnagel, RB et al. PLoS One, DOI://10.1371/journal.pone.0268149 (2022)
- Profiling the NOTCH2NLC GGC Repeat Expansion in Parkinson's Disease in the European Population Billingsley, KJ; Alvarez Jerez, P; Grenn, FP et al. Mov Disord, DOI://10.1002/mds.29155 (2022)
- Whole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry White, JA; Kaninjing, ET; Adeniji, KA et al. Cancer Res Commun, DOI://10.1158/2767-9764.CRC-22-0136 (2022)
- Evaluation of cutaneous immune response in a controlled human in vivo model of mosquito bites Guerrero, D; Vo, HTM; Lon, C et al. Nat Commun, DOI://10.1038/s41467-022-34534-9 (2022)
- A novel role for GalNAc-T2 dependent glycosylation in energy homeostasis Verzijl, CRC; Oldoni, F; Loaiza, N et al. Mol Metab, DOI://10.1016/j.molmet.2022.101472 (2022)
- Comorbidities and ethnic health disparities in the UK biobank Teagle, WL; Norris, ET; Rishishwar, L et al. JAMIA Open, DOI://10.1093/jamiaopen/ooac057 (2022)
- Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase Klemm, BP; Singh, D; Smith, CE et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2123092119 (2022)
- PUS7 deficiency in human patients causes profound neurodevelopmental phenotype by dysregulating protein translation Han, ST; Kim, AC; Garcia, K et al. Mol Genet Metab, DOI://10.1016/j.ymgme.2022.01.103 (2022)
- Comparison of transcranial sonography and [18F]-fluorodopa PET imaging in GBA1 mutation carriers Eisenberg, DP; Lopez, G; Gregory, MD et al. Mov Disord, DOI://10.1002/mds.28852 (2022)
- Natural and human-driven selection of a single non-coding body size variant in ancient and modern canids Plassais, J; vonHoldt, BM; Parker, HG et al. Curr Biol, DOI://10.1016/j.cub.2021.12.036 (2022)
- Quality control practices in FMRI analysis: Philosophy, methods and examples using AFNI Reynolds, RC; Taylor, PA; Glen, DR; , Front Neurosci, DOI://10.3389/fnins.2022.1073800 (2022)
- Adverse childhood experiences and premature mortality through mid-adulthood: A five-decade prospective study Yu, J; Patel, RA; Haynie, DL et al. Lancet Reg Health Am, DOI://10.1016/j.lana.2022.100349 (2022)
- Genetic testing in severe aplastic anemia is required for optimal hematopoietic cell transplant outcomes McReynolds, LJ; Rafati, M; Wang, Y et al. Blood, DOI://10.1182/blood.2022016508 (2022)
- A filarial parasite-encoded human IL-10 receptor antagonist reveals a novel strategy to modulate host responses Ricciardi, A; Hassan, SA; Kamenyeva, O et al. PNAS Nexus, DOI://10.1093/pnasnexus/pgac184 (2022)
- An Overview of D7 Protein Structure and Physiological Roles in Blood-Feeding Nematocera Alvarenga, PH; Andersen, JF; , Biology (Basel), DOI://10.3390/biology12010039 (2022)
- The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities Jiménez-Panizo, A; Alegre-Martí, A; Tettey, TT et al. Nucleic Acids Res, DOI://10.1093/nar/gkac1119 (2022)
- Transposase N-terminal phosphorylation and asymmetric transposon ends inhibit piggyBac transposition in mammalian cells Luo, W; Hickman, AB; Genzor, P et al. Nucleic Acids Res, DOI://10.1093/nar/gkac1191 (2022)
- Domestic dog lineages reveal genetic drivers of behavioral diversification Dutrow, EV; Serpell, JA; Ostrander, EA; , Cell, DOI://10.1016/j.cell.2022.11.003 (2022)
- Epidemiology of ICU-Onset Bloodstream Infection: Prevalence, Pathogens, and Risk Factors Among 150,948 ICU Patients at 85 U.S. Hospitals Gouel-Cheron, A; Swihart, BJ; Warner, S et al. Crit Care Med, DOI://10.1097/CCM.0000000000005662 (2022)
- Mito-SiPE is a sequence-independent and PCR-free mtDNA enrichment method for accurate ultra-deep mitochondrial sequencing Walsh, DJ; Bernard, DJ; Pangilinan, F et al. Commun Biol, DOI://10.1038/s42003-022-04182-2 (2022)
- Elevated cell-free DNA in respiratory viral infection and associated lung allograft dysfunction Bazemore, K; Permpalung, N; Mathew, J et al. Am J Transplant, DOI://10.1111/ajt.17125 (2022)
- Plasma Cell-Free DNA Predicts Survival and Maps Specific Sources of Injury in Pulmonary Arterial Hypertension Brusca, SB; Elinoff, JM; Zou, Y et al. Circulation, DOI://10.1161/CIRCULATIONAHA.121.056719 (2022)
- HAL-X: Scalable hierarchical clustering for rapid and tunable single-cell analysis Anibal, J; Day, AG; Bahadiroglu, E et al. PLoS Comput Biol, DOI://10.1371/journal.pcbi.1010349 (2022)
- Barcode clonal tracking of tissue-resident immune cells in rhesus macaque highlights distinct clonal distribution pattern of tissue NK cells Wu, C; Liang, JA; Brenchley, JM et al. Front Immunol, DOI://10.3389/fimmu.2022.994498 (2022)
- Systemic Inflammation is Associated with Cardiometabolic Risk Factors and Clinical Outcomes Tejada, B; Joehanes, R; Hwang, SJ et al. J Inflamm Res, DOI://10.2147/JIR.S382620 (2022)
- Serological responses to human virome define clinical outcomes of Italian patients infected with SARS-CoV-2 Wang, L; Candia, J; Ma, L et al. Int J Biol Sci, DOI://10.7150/ijbs.78002 (2022)
- Kidney tumors associated with germline mutations of FH and SDHB show a CpG island methylator phenotype (CIMP) Ricketts, CJ; Killian, JK; Vocke, CD et al. PLoS One, DOI://10.1371/journal.pone.0278108 (2022)
- A Mega-analytic Study of White Matter Microstructural Differences Across 5 Cohorts of Youths With Attention-Deficit/Hyperactivity Disorder Sudre, G; Norman, L; Bouyssi-Kobar, M et al. Biol Psychiatry, DOI://10.1016/j.biopsych.2022.09.021 (2022)
- Acute worsening of CADASIL in a patient with COVID-19 infection: illustrative case Rosenblum, JS; Tunacao, JM; Nazari, MA et al. J Neurosurg Case Lessons, DOI://10.3171/CASE22413 (2022)
- Evaluation of Cone- and Rod-Mediated Parameters in Dark Adaptation Testing as Outcome Measures in Age-Related Macular Degeneration Hess, K; de Silva, T; Grisso, P et al. Ophthalmol Retina, DOI://10.1016/j.oret.2022.05.018 (2022)
- Protocol for base resolution mapping of ac4C using RedaC:T-seq Sturgill, D; Arango, D; Oberdoerffer, S; , STAR Protoc, DOI://10.1016/j.xpro.2022.101858 (2022)
- COnstrained Reference frame diffusion TEnsor Correlation Spectroscopic (CORTECS) MRI: A practical framework for high-resolution diffusion tensor distribution imaging Avram, AV; Saleem, KS; Basser, PJ; , Front Neurosci, DOI://10.3389/fnins.2022.1054509 (2022)
- Association between microbial composition, diversity, and function of the maternal gastrointestinal microbiome with impaired glucose tolerance on the glucose challenge test Dreisbach, C; Prescott, S; Alhusen, J et al. PLoS One, DOI://10.1371/journal.pone.0271261 (2022)
- Identification and analysis of odorant receptors expressed in the two main olfactory organs, antennae and palps, of Schistocerca americana Boronat-Garcia, A; Iben, J; Dominguez-Martin, E; Stopfer, M; , Sci Rep, DOI://10.1038/s41598-022-27199-3 (2022)
- Comparison of out-of-field normal tissue dose estimates for pencil beam scanning proton therapy: MCNP6, PHITS, and TOPAS Griffin, KT; Yeom, YS; Mille, MM et al. Biomed Phys Eng Express, DOI://10.1088/2057-1976/acaab1 (2022)
- A Deeper Insight into the Tick Salivary Protein Families under the Light of Alphafold2 and Dali: Introducing the TickSialoFam 2.0 Database Mans, BJ; Andersen, JF; Ribeiro, JMC; , Int J Mol Sci, DOI://10.3390/ijms232415613 (2022)
- The paradigm shift: Heartbeat initiation without "the pacemaker cell" Maltsev, VA; Stern, MD; , Front Physiol, DOI://10.3389/fphys.2022.1090162 (2022)
- Hi-TrAC reveals division of labor of transcription factors in organizing chromatin loops Liu, S; Cao, Y; Cui, K et al. Nat Commun, DOI://10.1038/s41467-022-34276-8 (2022)
- Cryo-EM reveals the architecture of the PELP1-WDR18 molecular scaffold Gordon, J; Chapus, FL; Viverette, EG et al. Nat Commun, DOI://10.1038/s41467-022-34610-0 (2022)
- Cell type-specific changes in Wnt signaling and neuronal differentiation in the developing mouse cortex after prenatal alcohol exposure during neurogenesis Sambo, D; Gohel, C; Yuan, Q et al. Front Cell Dev Biol, DOI://10.3389/fcell.2022.1011974 (2022)
- Rad51-mediated interhomolog recombination during budding yeast meiosis is promoted by the meiotic recombination checkpoint and the conserved Pif1 helicase Ziesel, A; Weng, Q; Ahuja, JS et al. PLoS Genet, DOI://10.1371/journal.pgen.1010407 (2022)
- Adults with lysosomal storage diseases in the undiagnosed diseases network Xiao, C; Koziura, M; Cope, H et al. Mol Genet Genomic Med, DOI://10.1002/mgg3.2013 (2022)
- Modeling Dinophysis in Western Andalucía using an autoregressive hidden Markov model Aron, J; Albert, PS; Gribble, MO; , Environ Ecol Stat, DOI://10.1007/s10651-022-00534-7 (2022)
- Organ dose calculator for diagnostic nuclear medicine patients based on the ICRP reference voxel phantoms and biokinetic models Villoing, D; Kwon, TE; Pasqual, E et al. Biomed Phys Eng Express, DOI://10.1088/2057-1976/aca543 (2022)
- Temporal Improvements in COVID-19 Outcomes for Hospitalized Adults: A Post Hoc Observational Study of Remdesivir Group Participants in the Adaptive COVID-19 Treatment Trial Potter, GE; Bonnett, T; Rubenstein, K et al. Ann Intern Med, DOI://10.7326/M22-2116 (2022)
- Opposing functions of circadian protein DBP and atypical E2F family E2F8 in anti-tumor Th9 cell differentiation Park, SA; Lim, YJ; Ku, WL et al. Nat Commun, DOI://10.1038/s41467-022-33733-8 (2022)
- Structural basis of 3'-end poly(A) RNA recognition by LARP1 Kozlov, G; Mattijssen, S; Jiang, J et al. Nucleic Acids Res, DOI://10.1093/nar/gkac696 (2022)
- High-resolution cortical MAP-MRI reveals areal borders and laminar substructures observed with histological staining Avram, AV; Saleem, KS; Komlosh, ME et al. Neuroimage, DOI://10.1016/j.neuroimage.2022.119653 (2022)
- Transcriptional mapping of the macaque retina and RPE-choroid reveals conserved inter-tissue transcription drivers and signaling pathways Mungale, A; McGaughey, DM; Zhang, C et al. Front Genet, DOI://10.3389/fgene.2022.949449 (2022)
- A deep learning approach to identify missing is-a relations in SNOMED CT Abeysinghe, R; Zheng, F; Bernstam, EV et al. J Am Med Inform Assoc, DOI://10.1093/jamia/ocac248 (2022)
- An imputation approach for a time-to-event analysis subject to missing outcomes due to noncoverage in disease registries Shih, JH; Albert, PS; Fine, J; Liu, D; , Biostatistics, DOI://10.1093/biostatistics/kxac049 (2022)
- Insights into autoregulation of a membrane protein complex by its cytoplasmic domains Leone, V; Bradshaw, RT; Koshy, C et al. Biophys J, DOI://10.1016/j.bpj.2022.12.021 (2022)
- Structural variant analysis of a cancer reference cell line sample using multiple sequencing technologies Talsania, K; Shen, TW; Chen, X et al. Genome Biol, DOI://10.1186/s13059-022-02816-6 (2022)
- Massively parallel reporter assays and variant scoring identified functional variants and target genes for melanoma loci and highlighted cell-type specificity Long, E; Yin, J; Funderburk, KM et al. Am J Hum Genet, DOI://10.1016/j.ajhg.2022.11.006 (2022)
- Structural Determinants and Functional Significance of Dimerization for Osmosensing Transporter ProP in Escherichia coli Ozturk, TN; Coumoundouros, C; Culham, DE; Wood, JM; , Biochemistry, DOI://10.1021/acs.biochem.2c00393 (2022)
- Rare copy number variants in males and females with childhood attention-deficit/hyperactivity disorder Jung, B; Ahn, K; Justice, C et al. Mol Psychiatry, DOI://10.1038/s41380-022-01906-y (2022)
- Identification and characterization of proteins that form the inner core Ixodes scapularis tick attachment cement layer Mulenga, A; Radulovic, Z; Porter, L et al. Sci Rep, DOI://10.1038/s41598-022-24881-4 (2022)
- TULIP: An RNA-seq-based Primary Tumor Type Prediction Tool Using Convolutional Neural Networks Jones, S; Beyers, M; Shukla, M et al. Cancer Inform, DOI://10.1177/11769351221139491 (2022)
- Broad misappropriation of developmental splicing profile by cancer in multiple organs Singh, A; Rajeevan, A; Gopalan, V et al. Nat Commun, DOI://10.1038/s41467-022-35322-1 (2022)
- Molecular models of multiple sclerosis severity identify heterogeneity of pathogenic mechanisms Kosa, P; Barbour, C; Varosanec, M et al. Nat Commun, DOI://10.1038/s41467-022-35357-4 (2022)
- Sex Biases in Cancer and Autoimmune Disease Incidence Are Strongly Positively Correlated with Mitochondrial Gene Expression across Human Tissues Crawford, DR; Sinha, S; Nair, NU et al. Cancers (Basel), DOI://10.3390/cancers14235885 (2022)
- Systematic single-cell pathway analysis to characterize early T cell activation Bibby, JA; Agarwal, D; Freiwald, T et al. Cell Rep, DOI://10.1016/j.celrep.2022.111697 (2022)
- UPF1 mutants with intact ATPase but deficient helicase activities promote efficient nonsense-mediated mRNA decay Chapman, JH; Craig, JM; Wang, CD et al. Nucleic Acids Res, DOI://10.1093/nar/gkac1026 (2022)
- Planar aggregation of the influenza viral fusion peptide alters membrane structure and hydration, promoting poration Rice, A; Haldar, S; Wang, E et al. Nat Commun, DOI://10.1038/s41467-022-34576-z (2022)
- Active DNA demethylation promotes cell fate specification and the DNA damage response Wang, D; Wu, W; Callen, E et al. Science, DOI://10.1126/science.add9838 (2022)
- Non-parametric estimation of the age-at-onset distribution from a cross-sectional sample Mandal, S; Qin, J; Pfeiffer, RM; , Biometrics, DOI://10.1111/biom.13804 (2022)
- The tumour microenvironment shapes innate lymphoid cells in patients with hepatocellular carcinoma Heinrich, B; Gertz, EM; Schäffer, AA et al. Gut, DOI://10.1136/gutjnl-2021-325288 (2022)
- An Exact Hypergraph Matching algorithm for posture identification in embryonic C. elegans Lauziere, A; Christensen, R; Shroff, H; Balan, R; , PLoS One, DOI://10.1371/journal.pone.0277343 (2022)
- Creation of a new Drosophila melanogaster X chromosome balancer, First Multiple 8 ( FM8 ), using the CRISPR/Cas9 gene-editing system Muron, S; Kucera, S; Oliver, B; Benner, L; , MicroPubl Biol, DOI://10.17912/micropub.biology.000663 (2022)
- Rickettsia parkeri infection modulates the sialome and ovariome of the Gulf coast tick, Amblyomma maculatum Guizzo, MG; Budachetri, K; Adegoke, A et al. Front Microbiol, DOI://10.3389/fmicb.2022.1023980 (2022)
- Genomic study of maternal lipid traits in early pregnancy concurs with four known adult lipid loci Ouidir, M; Chatterjee, S; Wu, J; Tekola-Ayele, F; , J Clin Lipidol, DOI://10.1016/j.jacl.2022.10.013 (2022)
- Single cell atlas of spinal cord injury in mice reveals a pro-regenerative signature in spinocerebellar neurons Matson, KJE; Russ, DE; Kathe, C et al. Nat Commun, DOI://10.1038/s41467-022-33184-1 (2022)
- Epigenetic regulation of white adipose tissue plasticity and energy metabolism by nucleosome binding HMGN proteins Nanduri, R; Furusawa, T; Lobanov, A et al. Nat Commun, DOI://10.1038/s41467-022-34964-5 (2022)
- Anti-mesothelin immunotoxin induces mesothelioma eradication, anti-tumor immunity, and the development of tertiary lymphoid structures Liu, W; Tai, CH; Liu, X; Pastan, I; , Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2214928119 (2022)
- Specification of neuronal subtypes in the spiral ganglion begins prior to birth in the mouse Sanders, TR; Kelley, MW; , Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2203935119 (2022)
- Cryo-EM of prion strains from the same genotype of host identifies conformational determinants Hoyt, F; Alam, P; Artikis, E et al. PLoS Pathog, DOI://10.1371/journal.ppat.1010947 (2022)
- Characterization of Oncology Clinical Trials Using Germline Genetic Data Kammula, AV; Schäffer, AA; Rajagopal, PS; , JAMA Netw Open, DOI://10.1001/jamanetworkopen.2022.42370 (2022)
- Linear and nonlinear correlation estimators unveil undescribed taxa interactions in microbiome data Lin, H; Eggesbø, M; Peddada, SD; , Nat Commun, DOI://10.1038/s41467-022-32243-x (2022)
- Hypermutator strains of Pseudomonas aeruginosa reveal novel pathways of resistance to combinations of cephalosporin antibiotics and beta-lactamase inhibitors Chiang, AD; Patil, PP; Beka, L et al. PLoS Biol, DOI://10.1371/journal.pbio.3001878 (2022)
- Hydroxygenkwanin Improves the Efficacy of Cytotoxic Drugs in ABCG2-Overexpressing Multidrug-Resistant Cancer Cells Li, YQ; Murakami, M; Huang, YH et al. Int J Mol Sci, DOI://10.3390/ijms232112763 (2022)
- Mapping the cortico-striatal transcriptome in attention deficit hyperactivity disorder Sudre, G; Gildea, DE; Shastri, GG et al. Mol Psychiatry, DOI://10.1038/s41380-022-01844-9 (2022)
- Assigning species information to corresponding genes by a sequence labeling framework Luo, L; Wei, CH; Lai, PT et al. Database (Oxford), DOI://10.1093/database/baac090 (2022)
- Proteomic Landscape and Deduced Functions of the Cardiac 14-3-3 Protein Interactome Qu, JH; Tarasov, KV; Chakir, K et al. Cells, DOI://10.3390/cells11213496 (2022)
- The Solvation of the E. coli CheY Phosphorylation Site Mapped by XFMS Hamid, M; Khalid, MF; Chaudhary, SU; Khan, S; , Int J Mol Sci, DOI://10.3390/ijms232112771 (2022)
- A Bietti Crystalline Dystrophy Mouse Model Shows Increased Sensitivity to Light-Induced Injury Ma, Z; Jiao, X; Agbaga, MP et al. Int J Mol Sci, DOI://10.3390/ijms232113108 (2022)
- Intranasal delivery of a rationally attenuated SARS-CoV-2 is immunogenic and protective in Syrian hamsters Liu, S; Stauft, CB; Selvaraj, P et al. Nat Commun, DOI://10.1038/s41467-022-34571-4 (2022)
- Biological Variation of Donor-Derived Cell-Free DNA in Stable Lung Transplant Recipients Keller, M; Mutebi, C; Shah, P et al. J Appl Lab Med, DOI://10.1093/jalm/jfab171 (2022)
- Higher order interactions of Bcr-Abl can broaden chronic myeloid leukemia (CML) drug repertoire Liu, Y; Zhang, M; Jang, H; Nussinov, R; , Protein Sci, DOI://10.1002/pro.4504 (2022)
- Vaccination History, Body Mass Index, Age, and Baseline Gene Expression Predict Influenza Vaccination Outcomes Forst, CV; Chung, M; Hockman, M et al. Viruses, DOI://10.3390/v14112446 (2022)
- Retrotransposon insertions associated with risk of neurologic and psychiatric diseases Ahn, HW; Worman, ZF; Lechsinska, A et al. EMBO Rep, DOI://10.15252/embr.202255197 (2022)
- Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses Moin, SM; Boyington, JC; Boyoglu-Barnum, S et al. Immunity, DOI://10.1016/j.immuni.2022.10.015 (2022)
- Genome-wide profiling of retroviral DNA integration and its effect on clinical pre-infusion CAR T-cell products Shao, L; Shi, R; Zhao, Y et al. J Transl Med, DOI://10.1186/s12967-022-03729-5 (2022)
- Cryo-EM structures of prefusion SIV envelope trimer Gorman, J; Wang, C; Mason, RD et al. Nat Struct Mol Biol, DOI://10.1038/s41594-022-00852-1 (2022)
- Incorporating the image formation process into deep learning improves network performance Li, Y; Su, Y; Guo, M et al. Nat Methods, DOI://10.1038/s41592-022-01652-7 (2022)
- MOSAICS: A Software Suite for Analysis of Membrane Structure and Dynamics in Simulated Trajectories Bernhardt, N; Faraldo-Gómez, JD; , Biophys J, DOI://10.1016/j.bpj.2022.11.005 (2022)
- Common Gray Matter Reductions in Alcohol Use and Obsessive-Compulsive Disorders: A Meta-analysis Stevens, BW; Morris, JK; Diazgranados, N; Ramchandani, VA; , Biol Psychiatry Glob Open Sci, DOI://10.1016/j.bpsgos.2021.11.010 (2022)
- Integrative epigenomic analyses of small cell lung cancer cells demonstrates the clinical translational relevance of gene body methylation Pongor, LS; Tlemsani, C; Elloumi, F et al. iScience, DOI://10.1016/j.isci.2022.105338 (2022)
- Structural Mechanism of TAF-Iβ Chaperone Function on Linker Histone H1.10 Feng, H; Zhou, BR; Schwieters, CD; Bai, Y; , J Mol Biol, DOI://10.1016/j.jmb.2022.167755 (2022)
- Multiomics analyses reveal early metabolic imbalance and mitochondrial stress in neonatal photoreceptors leading to cell death in Pde6brd1/rd1 mouse model of retinal degeneration Jiang, K; Mondal, AK; Adlakha, YK et al. Hum Mol Genet, DOI://10.1093/hmg/ddac013 (2022)
- Machine learning based survival prediction in Glioma using large-scale registry data Zhao, R; Zhuge, Y; Camphausen, K; Krauze, AV; , Health Informatics J, DOI://10.1177/14604582221135427 (2022)
- NF kappa B regulator Bcl3 controls development and function of classical dendritic cells required for resistance to Toxoplasma gondii Guha, J; Kang, B; Claudio, E et al. PLoS Pathog, DOI://10.1371/journal.ppat.1010502 (2022)
- Changes in DNA methylation hallmark alterations in chromatin accessibility and gene expression for eye lens differentiation Disatham, J; Brennan, L; Jiao, X et al. Epigenetics Chromatin, DOI://10.1186/s13072-022-00440-z (2022)
- Pituitary adenomas evade apoptosis via noxa deregulation in Cushing's disease Asuzu, DT; Alvarez, R; Fletcher, PA et al. Cell Rep, DOI://10.1016/j.celrep.2022.111223 (2022)
- Computational Modeling and Imaging of the Intracellular Oxygen Gradient Sedlack, AJH; Penjweini, R; Link, KA et al. Int J Mol Sci, DOI://10.3390/ijms232012597 (2022)
- Limited cross-variant immune response from SARS-CoV-2 Omicron BA.2 in naïve but not previously infected outpatients Lee, HK; Knabl, L; Walter, M et al. iScience, DOI://10.1016/j.isci.2022.105369 (2022)
- An introduction to PIWI-interacting RNAs (piRNAs) in the context of metazoan small RNA silencing pathways Haase, AD RNA Biol, DOI://10.1080/15476286.2022.2132359 (2022)
- Time-Varying Gene Expression Network Analysis Reveals Conserved Transition States in Hematopoietic Differentiation between Human and Mouse Gao, S; Chen, Y; Wu, Z et al. Genes (Basel), DOI://10.3390/genes13101890 (2022)
- Strain level microbial detection and quantification with applications to single cell metagenomics Zhu, K; Schäffer, AA; Robinson, W et al. Nat Commun, DOI://10.1038/s41467-022-33869-7 (2022)
- Mechanism of 4-aminopyridine inhibition of the lysosomal channel TMEM175 Oh, S; Stix, R; Zhou, W et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2208882119 (2022)
- A compendium of co-regulated mitoribosomal proteins in pan-cancer uncovers collateral defective events in tumor malignancy Chang, CW; Wei, Z; Durell, SR et al. iScience, DOI://10.1016/j.isci.2022.105244 (2022)
- Ectopic expression of meiotic cohesin generates chromosome instability in cancer cell line Boukaba, A; Liu, J; Ward, C et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2204071119 (2022)
- Nuclear position modulates long-range chromatin interactions Finn, EH; Misteli, T; , PLoS Genet, DOI://10.1371/journal.pgen.1010451 (2022)
- A computational solution for bolstering reliability of epigenetic clocks: Implications for clinical trials and longitudinal tracking Higgins-Chen, AT; Thrush, KL; Wang, Y et al. Nat Aging, DOI://10.1038/s43587-022-00248-2 (2022)
- Micro-scale functional modules in the human temporal lobe Chapeton, JI; Wittig, JH; Inati, SK; Zaghloul, KA; , Nat Commun, DOI://10.1038/s41467-022-34018-w (2022)
- Maternal caffeine intake and DNA methylation in newborn cord blood Polinski, KJ; Purdue-Smithe, A; Robinson, SL et al. Am J Clin Nutr, DOI://10.1093/ajcn/nqab348 (2022)
- CT organ dose calculator size adaptive for pediatric and adult patients Lee, C; Yeom, YS; Folio, L; , Biomed Phys Eng Express, DOI://10.1088/2057-1976/ac9845 (2022)
- Semi-automated assembly of high-quality diploid human reference genomes Jarvis, ED; Formenti, G; Rhie, A et al. Nature, DOI://10.1038/s41586-022-05325-5 (2022)
- Impact of adjuvant: Trivalent vaccine with quadrivalent-like protection against heterologous Yamagata-lineage influenza B virus Myers, ML; Gallagher, JR; Woolfork, DD et al. Front Immunol, DOI://10.3389/fimmu.2022.1002286 (2022)
- Single-shot 3D shape acquisition using a learning-based structured-light technique Nguyen, AH; Ly, KL; Qiong Li, C; Wang, Z; , Appl Opt, DOI://10.1364/AO.470208 (2022)
- STING-induced regulatory B cells compromise NK function in cancer immunity Li, S; Mirlekar, B; Johnson, BM et al. Nature, DOI://10.1038/s41586-022-05254-3 (2022)
- Design of a Protein with Improved Thermal Stability by an Evolution-Based Generative Model Tian, P; Lemaire, A; Sénéchal, F et al. Angew Chem Int Ed Engl, DOI://10.1002/anie.202202711 (2022)
- Loss of CASZ1 tumor suppressor linked to oncogenic subversion of neuroblastoma core regulatory circuitry Liu, Z; Zhang, X; Xu, M et al. Cell Death Dis, DOI://10.1038/s41419-022-05314-6 (2022)
- Ancestry-specific high-risk gene variant profiling unmasks diabetes-associated genes Zhang, J; Chen, W; Chen, G et al. Hum Mol Genet, DOI://10.1093/hmg/ddac255 (2022)
- CellCallEXT: Analysis of Ligand-Receptor and Transcription Factor Activities in Cell-Cell Communication of Tumor Immune Microenvironment Gao, S; Feng, X; Wu, Z et al. Cancers (Basel), DOI://10.3390/cancers14194957 (2022)
- Disentangling autoproteolytic cleavage from tethered agonist-dependent activation of the adhesion receptor ADGRL3 Perry-Hauser, NA; VanDyck, MW; Lee, KH et al. J Biol Chem, DOI://10.1016/j.jbc.2022.102594 (2022)
- Clinical utility of family history of depression for prognosis of adolescent depression severity and duration assessed with predictive modeling Gorham, LS; Sadeghi, N; Eisner, L et al. J Child Psychol Psychiatry, DOI://10.1111/jcpp.13547 (2022)
- Misconfigured striatal connectivity profiles in smokers Korponay, C; Stein, EA; Ross, TJ; , Neuropsychopharmacology, DOI://10.1038/s41386-022-01366-6 (2022)
- A cerebellar-prepontine circuit for tonic immobility triggered by an inescapable threat Bhandiwad, AA; Chu, NC; Semenova, SA et al. Sci Adv, DOI://10.1126/sciadv.abo0549 (2022)
- Protein kinase CK2 modulates the activity of Maf-family bZIP transcription factor NRL in rod photoreceptors of mammalian retina Liang, X; Yadav, SP; Batz, ZA et al. Hum Mol Genet, DOI://10.1093/hmg/ddac256 (2022)
- High-resolution genome topology of human retina uncovers super enhancer-promoter interactions at tissue-specific and multifactorial disease loci Marchal, C; Singh, N; Batz, Z et al. Nat Commun, DOI://10.1038/s41467-022-33427-1 (2022)
- A regulatory network of Sox and Six transcription factors initiate a cell fate transformation during hearing regeneration in adult zebrafish Jimenez, E; Slevin, CC; Song, W et al. Cell Genom, DOI://10.1016/j.xgen.2022.100170 (2022)
- A miniature fluorescence microscope for multi-plane imaging Barbera, G; Jun, R; Zhang, Y et al. Sci Rep, DOI://10.1038/s41598-022-21022-9 (2022)
- Fully Automated and Explainable Liver Segmental Volume Ratio and Spleen Segmentation at CT for Diagnosing Cirrhosis Lee, S; Elton, DC; Yang, AH et al. Radiol Artif Intell, DOI://10.1148/ryai.210268 (2022)
- Setting Up a Better Infection: Overexpression of the Early Bacteriophage T4 Gene motB During Infection Results in a More Favorable tRNA Pool for the Phage Son, B; Patterson-West, J; Thompson, CO et al. Phage (New Rochelle), DOI://10.1089/phage.2022.0023 (2022)
- Molecular and clinicopathologic characteristics of gliomas with EP300::BCOR fusions Wu, Z; Rajan, S; Chung, HJ et al. Acta Neuropathol, DOI://10.1007/s00401-022-02508-2 (2022)
- TFSyntax: a database of transcription factors binding syntax in mammalian genomes Zhao, Y Nucleic Acids Res, DOI://10.1093/nar/gkac849 (2022)
- "Stripe" transcription factors provide accessibility to co-binding partners in mammalian genomes Zhao, Y; Vartak, SV; Conte, A et al. Mol Cell, DOI://10.1016/j.molcel.2022.06.029 (2022)
- Progression of prostate cancer reprograms MYC-mediated lipid metabolism via lysine methyltransferase 2A Whitlock, NC; White, ME; Capaldo, BJ et al. Discov Oncol, DOI://10.1007/s12672-022-00565-3 (2022)
- Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5 Saha, S; Yang, X; Huang, SN et al. Cell Rep, DOI://10.1016/j.celrep.2022.111067 (2022)
- Abdominal CT Body Composition Thresholds Using Automated AI Tools for Predicting 10-year Adverse Outcomes Lee, MH; Zea, R; Garrett, JW et al. Radiology, DOI://10.1148/radiol.220574 (2022)
- HIV-1 Vpr suppresses expression of the thiazide-sensitive sodium chloride co-transporter in the distal convoluted tubule Shrivastav, S; Lee, H; Okamoto, K et al. PLoS One, DOI://10.1371/journal.pone.0273313 (2022)
- An optimized bicistronic chimeric antigen receptor against GPC2 or CD276 overcomes heterogeneous expression in neuroblastoma Tian, M; Cheuk, AT; Wei, JS et al. J Clin Invest, DOI://10.1172/JCI155621 (2022)
- Creatine riboside is a cancer cell-derived metabolite associated with arginine auxotrophy Parker, AL; Toulabi, L; Oike, T et al. J Clin Invest, DOI://10.1172/JCI157410 (2022)
- OMA1 mediates local and global stress responses against protein misfolding in CHCHD10 mitochondrial myopathy Shammas, MK; Huang, X; Wu, BP et al. J Clin Invest, DOI://10.1172/JCI157504 (2022)
- Single-cell sequencing reveals activation of core transcription factors in PRC2-deficient malignant peripheral nerve sheath tumor Zhang, X; Lou, HE; Gopalan, V et al. Cell Rep, DOI://10.1016/j.celrep.2022.111363 (2022)
- Tea Consumption and All-Cause and Cause-Specific Mortality in the UK Biobank : A Prospective Cohort Study Inoue-Choi, M; Ramirez, Y; Cornelis, MC et al. Ann Intern Med, DOI://10.7326/M22-0041 (2022)
- ADHD and its neurocognitive substrates: A two sample Mendelian randomization study Ahn, K; Norman, LJ; Justice, CM; Shaw, P; , Transl Psychiatry, DOI://10.1038/s41398-022-02139-x (2022)
- HMI-PRED 2.0: a biologist-oriented web application for prediction of host-microbe protein-protein interaction by interface mimicry Lim, H; Tsai, CJ; Keskin, O et al. Bioinformatics, DOI://10.1093/bioinformatics/btac633 (2022)
- Adding an Attention Layer Improves the Performance of a Neural Network Architecture for Synonymy Prediction in the UMLS Metathesaurus Nguyen, V; Bodenreider, O; , Stud Health Technol Inform, DOI://10.3233/SHTI220043 (2022)
- Development of ultra-high affinity bivalent ligands targeting the polo-like kinase 1 Tsuji, K; Hymel, D; Ma, B et al. RSC Chem Biol, DOI://10.1039/d2cb00153e (2022)
- Atlas of regulated target genes of transcription factors (ART-TF) in human ES cells Sharov, AA; Nakatake, Y; Wang, W; , BMC Bioinformatics, DOI://10.1186/s12859-022-04924-3 (2022)
- Disruption of grin2B, an ASD-associated gene, produces social deficits in zebrafish Zoodsma, JD; Keegan, EJ; Moody, GR et al. Mol Autism, DOI://10.1186/s13229-022-00516-3 (2022)
- Zrsr2 Is Essential for the Embryonic Development and Splicing of Minor Introns in RNA and Protein Processing Genes in Zebrafish Weinstein, R; Bishop, K; Broadbridge, E et al. Int J Mol Sci, DOI://10.3390/ijms231810668 (2022)
- Multiple Nf1 Schwann cell populations reprogram the plexiform neurofibroma tumor microenvironment Kershner, LJ; Choi, K; Wu, J et al. JCI Insight, DOI://10.1172/jci.insight.154513 (2022)
- Transcriptomic architecture of nuclei in the marmoset CNS Lin, JP; Kelly, HM; Song, Y et al. Nat Commun, DOI://10.1038/s41467-022-33140-z (2022)
- Context-Enriched Learning Models for Aligning Biomedical Vocabularies at Scale in the UMLS Metathesaurus Nguyen, V; Yip, HY; Bajaj, G et al. Proc Int World Wide Web Conf, DOI://10.1145/3485447.3511946 (2022)
- Turning coldspots into hotspots: targeted recruitment of axis protein Hop1 stimulates meiotic recombination in Saccharomyces cerevisiae Shodhan, A; Xaver, M; Wheeler, D; Lichten, M; , Genetics, DOI://10.1093/genetics/iyac106 (2022)
- Association of a common genetic variant with Parkinson's disease is mediated by microglia Langston, RG; Beilina, A; Reed, X et al. Sci Transl Med, DOI://10.1126/scitranslmed.abp8869 (2022)
- Glioma progression is shaped by genetic evolution and microenvironment interactions Varn, FS; Johnson, KC; Martinek, J et al. Cell, DOI://10.1016/j.cell.2022.04.038 (2022)
- Anti-GD2 Antibodies Conjugated to IL15 and IL21 Mediate Potent Antitumor Cytotoxicity against Neuroblastoma Nguyen, R; Zhang, X; Sun, M et al. Clin Cancer Res, DOI://10.1158/1078-0432.CCR-22-0717 (2022)
- The oxidoreductase CLIC4 is required to maintain mitochondrial function and resistance to exogenous oxidants in breast cancer cells Al Khamici, H; Sanchez, VC; Yan, H et al. J Biol Chem, DOI://10.1016/j.jbc.2022.102275 (2022)
- Evidence from "big data" for the default-mode hypothesis of ADHD: a mega-analysis of multiple large samples Norman, LJ; Sudre, G; Price, J et al. Neuropsychopharmacology, DOI://10.1038/s41386-022-01408-z (2022)
- Germline-somatic JAK2 interactions are associated with clonal expansion in myelofibrosis Brown, DW; Zhou, W; Wang, Y et al. Nat Commun, DOI://10.1038/s41467-022-32986-7 (2022)
- The astroglial and stem cell functions of adult rat folliculostellate cells Fletcher, PA; Smiljanic, K; Prévide, RM et al. Glia, DOI://10.1002/glia.24267 (2022)
- Transcriptome-Wide Effects of NusA on RNA Polymerase Pausing in Bacillus subtilis Jayasinghe, OT; Mandell, ZF; Yakhnin, AV et al. J Bacteriol, DOI://10.1128/jb.00534-21 (2022)
- Brain-wide functional connectivity of face patch neurons during rest Zaldivar, D; Koyano, KW; Ye, FQ et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2206559119 (2022)
- Aging exacerbates the brain inflammatory micro-environment contributing to α-synuclein pathology and functional deficits in a mouse model of DLB/PD Iba, M; McDevitt, RA; Kim, C et al. Mol Neurodegener, DOI://10.1186/s13024-022-00564-6 (2022)
- De novo frameshift mutation in YAP1 associated with bilateral uveal coloboma and microphthalmia DeYoung, C; Guan, B; Ullah, E et al. Ophthalmic Genet, DOI://10.1080/13816810.2022.2028299 (2022)
- Longitudinal analysis reveals age-related changes in the T cell receptor repertoire of human T cell subsets Sun, X; Nguyen, T; Achour, A et al. J Clin Invest, DOI://10.1172/JCI158122 (2022)
- Heterogeneity and transcriptome changes of human CD8+ T cells across nine decades of life Lu, J; Ahmad, R; Nguyen, T et al. Nat Commun, DOI://10.1038/s41467-022-32869-x (2022)
- miRSCAPE - inferring miRNA expression from scRNA-seq data Olgun, G; Gopalan, V; Hannenhalli, S; , iScience, DOI://10.1016/j.isci.2022.104962 (2022)
- Cannabinoid receptor 2 activation alleviates diabetes-induced cardiac dysfunction, inflammation, oxidative stress, and fibrosis Rajesh, M; Mukhopadhyay, P; Bátkai, S et al. Geroscience, DOI://10.1007/s11357-022-00565-9 (2022)
- Disrupted control of origin activation compromises genome integrity upon destabilization of Polε and dysfunction of the TRP53-CDKN1A/P21 axis Borel, V; Boeing, S; Van Wietmarschen, N et al. Cell Rep, DOI://10.1016/j.celrep.2022.110871 (2022)
- An alternative UPF1 isoform drives conditional remodeling of nonsense-mediated mRNA decay Fritz, SE; Ranganathan, S; Wang, CD; Hogg, JR; , EMBO J, DOI://10.15252/embj.2021108898 (2022)
- Validation and Comparison of Radiograph-Based Organ Dose Reconstruction Approaches for Wilms Tumor Radiation Treatment Plans Wang, Z; Virgolin, M; Balgobind, BV et al. Adv Radiat Oncol, DOI://10.1016/j.adro.2022.101015 (2022)
- Allosteric regulation of autoinhibition and activation of c-Abl Liu, Y; Zhang, M; Tsai, CJ et al. Comput Struct Biotechnol J, DOI://10.1016/j.csbj.2022.08.014 (2022)
- Mcm2 hypomorph leads to acute leukemia or hematopoietic stem cell failure, dependent on genetic context Matsukawa, T; Yin, M; Baslan, T et al. FASEB J, DOI://10.1096/fj.202200061RR (2022)
- Recurrent ACVR1 mutations in posterior fossa ependymoma Pratt, D; Lucas, CG; Selvam, PP et al. Acta Neuropathol, DOI://10.1007/s00401-022-02435-2 (2022)
- Heterozygous PRKN mutations are common but do not increase the risk of Parkinson's disease Zhu, W; Huang, X; Yoon, E et al. Brain, DOI://10.1093/brain/awab456 (2022)
- An inactivated multivalent influenza A virus vaccine is broadly protective in mice and ferrets Park, J; Fong Legaspi, SL; Schwartzman, LM et al. Sci Transl Med, DOI://10.1126/scitranslmed.abo2167 (2022)
- The oral microbiome and breast cancer and nonmalignant breast disease, and its relationship with the fecal microbiome in the Ghana Breast Health Study Wu, Z; Byrd, DA; Wan, Y et al. Int J Cancer, DOI://10.1002/ijc.34145 (2022)
- The developmentally timed decay of an essential microRNA family is seed-sequence dependent Donnelly, BF; Yang, B; Grimme, AL et al. Cell Rep, DOI://10.1016/j.celrep.2022.111154 (2022)
- Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor-Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors Kim, SP; Vale, NR; Zacharakis, N et al. Cancer Immunol Res, DOI://10.1158/2326-6066.CIR-22-0040 (2022)
- BEND3 safeguards pluripotency by repressing differentiation-associated genes Kurniawan, F; Chetlangia, N; Kamran, M et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2107406119 (2022)
- Enhancer looping protein LDB1 regulates hepatocyte gene expression by cooperating with liver transcription factors Liu, G; Wang, L; Wess, J; Dean, A; , Nucleic Acids Res, DOI://10.1093/nar/gkac707 (2022)
- Machine Learning in Infectious Disease for Risk Factor Identification and Hypothesis Generation: Proof of Concept Using Invasive Candidiasis Mayer, LM; Strich, JR; Kadri, SS et al. Open Forum Infect Dis, DOI://10.1093/ofid/ofac401 (2022)
- Anti-Fibrotic Potential of Tomentosenol A, a Constituent of Cerumen from the Australian Native Stingless Bee, Tetragonula carbonaria Hamilton, KD; Czajkowski, D; Kong, NJ et al. Antioxidants (Basel), DOI://10.3390/antiox11081604 (2022)
- Accurately Identifying Cerebroarterial Stenosis from Angiography Reports Using Natural Language Processing Approaches Lin, CH; Hsu, KC; Liang, CK et al. Diagnostics (Basel), DOI://10.3390/diagnostics12081882 (2022)
- Satellite glia modulate sympathetic neuron survival, activity, and autonomic function Mapps, AA; Boehm, E; Beier, C et al. Elife, DOI://10.7554/eLife.74295 (2022)
- Gain-of-function mutations in ALPK1 cause an NF-κB-mediated autoinflammatory disease: functional assessment, clinical phenotyping and disease course of patients with ROSAH syndrome Kozycki, CT; Kodati, S; Huryn, L et al. Ann Rheum Dis, DOI://10.1136/annrheumdis-2022-222629 (2022)
- Dynamic model of monovalent-divalent cation exchange in polyelectrolyte gels Matan Mussel, Owen Lewis, Peter J. Basser, and Ferenc Horkay Phys. Rev. Materials 6:035602 (2022)
- The NIMH intramural healthy volunteer dataset: A comprehensive MEG, MRI, and behavioral resource Nugent, AC; Thomas, AG; Mahoney, M et al. Sci Data, DOI://10.1038/s41597-022-01623-9 (2022)
- MHC-independent αβT cells: Lessons learned about thymic selection and MHC-restriction Van Laethem, F; Bhattacharya, A; Craveiro, M et al. Front Immunol, DOI://10.3389/fimmu.2022.953160 (2022)
- Inhibitor of DNA binding proteins revealed as orchestrators of steady state, stress and malignant hematopoiesis Singh, S; Sarkar, T; Jakubison, B et al. Front Immunol, DOI://10.3389/fimmu.2022.934624 (2022)
- Molecular dynamics study of the swelling and osmotic properties of compact nanogel particles Chremos, A; Douglas, JF; Basser, PJ; Horkay, F; , Soft Matter, DOI://10.1039/d2sm00681b (2022)
- A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids Ramdas, S; Judd, J; Graham, SE et al. Am J Hum Genet, DOI://10.1016/j.ajhg.2022.06.012 (2022)
- Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine Arango, D; Sturgill, D; Yang, R et al. Mol Cell, DOI://10.1016/j.molcel.2022.05.016 (2022)
- Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies Gorski, M; Rasheed, H; Teumer, A et al. Kidney Int, DOI://10.1016/j.kint.2022.05.021 (2022)
- Transcription factors TCF-1 and GATA3 are key factors for the epigenetic priming of early innate lymphoid progenitors toward distinct cell fates Ren, G; Lai, B; Harly, C et al. Immunity, DOI://10.1016/j.immuni.2022.06.019 (2022)
- The amyloid concentric β-barrel hypothesis: Models of amyloid beta 42 oligomers and annular protofibrils Durell, SR; Kayed, R; Guy, HR; , Proteins, DOI://10.1002/prot.26301 (2022)
- Ultra-slow fMRI fluctuations in the fourth ventricle as a marker of drowsiness Gonzalez-Castillo, J; Fernandez, IS; Handwerker, DA; Bandettini, PA; , Neuroimage, DOI://10.1016/j.neuroimage.2022.119424 (2022)
- Brain charts for the human lifespan Bethlehem, RAI; Seidlitz, J; White, SR et al. Nature, DOI://10.1038/s41586-022-04554-y (2022)
- scPCOR-seq enables co-profiling of chromatin occupancy and RNAs in single cells Pan, L; Ku, WL; Tang, Q et al. Commun Biol, DOI://10.1038/s42003-022-03584-6 (2022)
- IL27 Signaling Serves as an Immunologic Checkpoint for Innate Cytotoxic Cells to Promote Hepatocellular Carcinoma Aghayev, T; Mazitova, AM; Fang, JR et al. Cancer Discov, DOI://10.1158/2159-8290.CD-20-1628 (2022)
- Comprehensive short and long read sequencing analysis for the Gaucher and Parkinson's disease-associated GBA gene Toffoli, M; Chen, X; Sedlazeck, FJ et al. Commun Biol, DOI://10.1038/s42003-022-03610-7 (2022)
- Cross-species identification of cancer resistance-associated genes that may mediate human cancer risk Nair, NU; Cheng, K; Naddaf, L et al. Sci Adv, DOI://10.1126/sciadv.abj7176 (2022)
- Assessment of Androgen Receptor Splice Variant-7 as a Biomarker of Clinical Response in Castration-Sensitive Prostate Cancer Sowalsky, AG; Figueiredo, I; Lis, RT et al. Clin Cancer Res, DOI://10.1158/1078-0432.CCR-22-0851 (2022)
- An epigenome atlas of neural progenitors within the embryonic mouse forebrain Rhodes, CT; Thompson, JJ; Mitra, A et al. Nat Commun, DOI://10.1038/s41467-022-31793-4 (2022)
- Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation Mahajan, A; Spracklen, CN; Zhang, W et al. Nat Genet, DOI://10.1038/s41588-022-01058-3 (2022)
- Chromatin structure undergoes global and local reorganization during murine dendritic cell development and activation Kurotaki, D; Kikuchi, K; Cui, K et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2207009119 (2022)
- NURF301 contributes to gypsy chromatin insulator-mediated nuclear organization Chen, S; Rosin, LF; Pegoraro, G et al. Nucleic Acids Res, DOI://10.1093/nar/gkac600 (2022)
- Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly Li, H; Janssens, J; De Waegeneer, M et al. Science, DOI://10.1126/science.abk2432 (2022)
- Reusable Single Cell for Iterative Epigenomic Analyses Ohnuki, H; Venzon, DJ; Lobanov, A; Tosato, G; , J Vis Exp, DOI://10.3791/63456 (2022)
- A Cascaded Deep Learning-Based Artificial Intelligence Algorithm for Automated Lesion Detection and Classification on Biparametric Prostate Magnetic Resonance Imaging Mehralivand, S; Yang, D; Harmon, SA et al. Acad Radiol, DOI://10.1016/j.acra.2021.08.019 (2022)
- Late-onset Proteus syndrome with cerebriform connective tissue nevus and subsequent development of intraductal papilloma Modlin, EW; Slavotinek, AM; Darling, TN et al. Am J Med Genet A, DOI://10.1002/ajmg.a.62761 (2022)
- Genome-wide regulation of KSHV RNA splicing by viral RNA-binding protein ORF57 Majerciak, V; Alvarado-Hernandez, B; Lobanov, A et al. PLoS Pathog, DOI://10.1371/journal.ppat.1010311 (2022)
- Causes and functional intricacies of inter- and intratumor heterogeneity of primary liver cancers Khatib, SA; Wang, XW; , Adv Cancer Res, DOI://10.1016/bs.acr.2022.01.006 (2022)
- Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer Byun, J; Han, Y; Li, Y et al. Nat Genet, DOI://10.1038/s41588-022-01115-x (2022)
- Flipped over U: structural basis for dsRNA cleavage by the SARS-CoV-2 endoribonuclease Frazier, MN; Wilson, IM; Krahn, JM et al. Nucleic Acids Res, DOI://10.1093/nar/gkac589 (2022)
- Sex-specific transcriptome differences in a middle-aged frailty cohort Pacheco, NL; Noren Hooten, N; Zhang, Y et al. BMC Geriatr, DOI://10.1186/s12877-022-03326-7 (2022)
- Reversal of the T cell immune system reveals the molecular basis for T cell lineage fate determination in the thymus Shinzawa, M; Moseman, EA; Gossa, S et al. Nat Immunol, DOI://10.1038/s41590-022-01187-1 (2022)
- Intestinal microbiota signatures of clinical response and immune-related adverse events in melanoma patients treated with anti-PD-1 McCulloch, JA; Davar, D; Rodrigues, RR et al. Nat Med, DOI://10.1038/s41591-022-01698-2 (2022)
- Disorders of ubiquitylation: unchained inflammation Beck, DB; Werner, A; Kastner, DL; Aksentijevich, I; , Nat Rev Rheumatol, DOI://10.1038/s41584-022-00778-4 (2022)
- Single-cell biology uncovers apoptotic cell death and its spatial organization as a potential modifier of tumor diversity in HCC Khatib, SA; Ma, L; Dang, H et al. Hepatology, DOI://10.1002/hep.32345 (2022)
- Questionnaire-based exposome-wide association studies (ExWAS) reveal expected and novel risk factors associated with cardiovascular outcomes in the Personalized Environment and Genes Study Lee, EY; Akhtari, F; House, JS et al. Environ Res, DOI://10.1016/j.envres.2022.113463 (2022)
- FOXM1 network in association with TREM1 suppression regulates NET formation in diabetic foot ulcers Sawaya, AP; Stone, RC; Mehdizadeh, S et al. EMBO Rep, DOI://10.15252/embr.202154558 (2022)
- Disorder in Ca2+ release unit locations confers robustness but cuts flexibility of heart pacemaking Maltsev, AV; Stern, MD; Maltsev, VA; , J Gen Physiol, DOI://10.1085/jgp.202113061 (2022)
- Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension Kelly, TN; Sun, X; He, KY et al. Hypertension, DOI://10.1161/HYPERTENSIONAHA.122.19324 (2022)
- Malignant melanocytic schwannian tumor and leptomeningeal disease: A case series with a focus on management Woodford, R; Prather, L; Helfer, C et al. J Neurol Sci, DOI://10.1016/j.jns.2022.120291 (2022)
- Pulmonary Function and Blood DNA Methylation: A Multiancestry Epigenome-Wide Association Meta-analysis Lee, M; Huan, T; McCartney, DL et al. Am J Respir Crit Care Med, DOI://10.1164/rccm.202108-1907OC (2022)
- A deeper insight into the sialome of male and female Ochlerotatus triseriatus mosquitoes Lu, S; Martin-Martin, I; Ribeiro, JM; Calvo, E; , Insect Biochem Mol Biol, DOI://10.1016/j.ibmb.2022.103800 (2022)
- Genetic regulation of OAS1 nonsense-mediated decay underlies association with COVID-19 hospitalization in patients of European and African ancestries Banday, AR; Stanifer, ML; Florez-Vargas, O et al. Nat Genet, DOI://10.1038/s41588-022-01113-z (2022)
- Epigenetic Reprogramming Leads to Downregulation of CD4 and Functional Changes in African Green Monkey Memory CD4 + T Cells Rahmberg, AR; Markowitz, TE; Mudd, JC et al. J Immunol, DOI://10.4049/jimmunol.2200109 (2022)
- Single-Cell Analysis of the Transcriptome and Epigenome Mazan-Mamczarz, K; Ha, J; De, S; Sen, P; , Methods Mol Biol, DOI://10.1007/978-1-0716-1831-8_3 (2022)
- The oral microbiome and lung cancer risk: An analysis of 3 prospective cohort studies Vogtmann, E; Hua, X; Yu, G et al. J Natl Cancer Inst, DOI://10.1093/jnci/djac149 (2022)
- Novel GLCCI1-BRAF fusion drives kinase signaling in a case of pheochromocytomatosis Green, BL; Grant, RRC; Richie, CT et al. Eur J Endocrinol, DOI://10.1530/EJE-21-0797 (2022)
- Neoantigen Identification and Response to Adoptive Cell Transfer in Anti-PD-1 Naïve and Experienced Patients with Metastatic Melanoma Levi, ST; Copeland, AR; Nah, S et al. Clin Cancer Res, DOI://10.1158/1078-0432.CCR-21-4499 (2022)
- Clonal hematopoiesis in patients with ANKRD26 or ETV6 germline mutations Drazer, MW; Homan, CC; Yu, K et al. Blood Adv, DOI://10.1182/bloodadvances.2022007211 (2022)
- Gene-level association analysis of ordinal traits with functional ordinal logistic regressions Chiu, CY; Wang, S; Zhang, B et al. Genet Epidemiol, DOI://10.1002/gepi.22451 (2022)
- Emergence of Irregular Activity in Networks of Strongly Coupled Conductance-Based Neurons Sanzeni, A; Histed, MH; Brunel, N; Phys Rev X, DOI://10.1103/physrevx.12.011044 (2022)
- Cholesterol Binds the Amphipathic Helix of IFITM3 and Regulates Antiviral Activity Rahman, K; Datta, SAK; Beaven, AH et al. J Mol Biol, DOI://10.1016/j.jmb.2022.167759 (2022)
- Causal and putative pathogenic mutations identified in 39% of children with primary steroid-resistant nephrotic syndrome in South Africa Nandlal, L; Winkler, CA; Bhimma, R et al. Eur J Pediatr, DOI://10.1007/s00431-022-04581-x (2022)
- ID2 and HIF-1α collaborate to protect quiescent hematopoietic stem cells from activation, differentiation, and exhaustion Jakubison, BL; Sarkar, T; Gudmundsson, KO et al. J Clin Invest, DOI://10.1172/JCI152599 (2022)
- Whole Genome DNA and RNA Sequencing of Whole Blood Elucidates the Genetic Architecture of Gene Expression Underlying a Wide Range of Diseases Liu, C; Joehanes, R; Ma, J et al. Res Sq, DOI://10.21203/rs.3.rs-1598646/v1 (2022)
- Polyoxovanadates as new P-glycoprotein inhibitors: insights into the mechanism of inhibition Kita, DH; de Andrade, GA; Missina, JM et al. FEBS Lett, DOI://10.1002/1873-3468.14265 (2022)
- Large-scale mapping of positional changes of hypoxia-responsive genes upon activation Nakayama, K; Shachar, S; Finn, EH et al. Mol Biol Cell, DOI://10.1091/mbc.E21-11-0593 (2022)
- Breast Cancers Are Immunogenic: Immunologic Analyses and a Phase II Pilot Clinical Trial Using Mutation-Reactive Autologous Lymphocytes Zacharakis, N; Huq, LM; Seitter, SJ et al. J Clin Oncol, DOI://10.1200/JCO.21.02170 (2022)
- M6A RNA Methylation Regulates Histone Ubiquitination to Support Cancer Growth and Progression Yadav, P; Subbarayalu, P; Medina, D et al. Cancer Res, DOI://10.1158/0008-5472.CAN-21-2106 (2022)
- Integrative analysis of clinical and epigenetic biomarkers of mortality Huan, T; Nguyen, S; Colicino, E et al. Aging Cell, DOI://10.1111/acel.13608 (2022)
- Repeat expansions nested within tandem CNVs: A unique structural change in GLS exemplifies the diagnostic challenges of non-coding pathogenic variation Fazal, S; Danzi, MC; van Kuilenburg, ABP et al. Hum Mol Genet, DOI://10.1093/hmg/ddac173 (2022)
- Magnetoencephalographic correlates of mood and reward dynamics in human adolescents Liuzzi, L; Chang, KK; Zheng, C et al. Cereb Cortex, DOI://10.1093/cercor/bhab417 (2022)
- MicrobiomeGWAS: A Tool for Identifying Host Genetic Variants Associated with Microbiome Composition Hua, X; Song, L; Yu, G et al. Genes (Basel), DOI://10.3390/genes13071224 (2022)
- Role of Lysosomal Gene Variants in Modulating GBA-Associated Parkinson's Disease Risk Straniero, L; Rimoldi, V; Monfrini, E et al. Mov Disord, DOI://10.1002/mds.28987 (2022)
- Oxysterol derivatives Oxy186 and Oxy210 inhibit WNT signaling in non-small cell lung cancer Tang, LY; Spezia, M; Chen, T et al. Cell Biosci, DOI://10.1186/s13578-022-00857-9 (2022)
- Identification of Daboia siamensis venome using integrated multi-omics data Saethang, T; Somparn, P; Payungporn, S et al. Sci Rep, DOI://10.1038/s41598-022-17300-1 (2022)
- Arsenic Exposure, Blood DNA Methylation, and Cardiovascular Disease Domingo-Relloso, A; Makhani, K; Riffo-Campos, AL et al. Circ Res, DOI://10.1161/CIRCRESAHA.122.320991 (2022)
- Identification of genomic determinants contributing to cytokine release in immunotherapies and human diseases Shao, L; Pelayo, A; Shi, R et al. J Transl Med, DOI://10.1186/s12967-022-03531-3 (2022)
- Cavβ1 regulates T cell expansion and apoptosis independently of voltage-gated Ca2+ channel function Erdogmus, S; Concepcion, AR; Yamashita, M et al. Nat Commun, DOI://10.1038/s41467-022-29725-3 (2022)
- Unravelling the distinct biological functions and potential therapeutic applications of TIMP2 in cancer Peeney, D; Liu, Y; Lazaroff, C et al. Carcinogenesis, DOI://10.1093/carcin/bgac037 (2022)
- NuRD complex recruitment to Thpok mediates CD4 + T cell lineage differentiation Gao, Y; Zamisch, M; Vacchio, M et al. Sci Immunol, DOI://10.1126/sciimmunol.abn5917 (2022)
- Single-cell transcriptome and accessible chromatin dynamics during endocrine pancreas development Duvall, E; Benitez, CM; Tellez, K et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2201267119 (2022)
- High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP Klemm, BP; Sikkema, AP; Hsu, AL et al. J Biol Chem, DOI://10.1016/j.jbc.2022.102073 (2022)
- Predicting cancer immunotherapy response from gut microbiomes using machine learning models Liang, H; Jo, JH; Zhang, Z et al. Oncotarget, DOI://10.18632/oncotarget.28252 (2022)
- Extensive co-binding and rapid redistribution of NANOG and GATA6 during emergence of divergent lineages Thompson, JJ; Lee, DJ; Mitra, A et al. Nat Commun, DOI://10.1038/s41467-022-31938-5 (2022)
- Spatial meta-transcriptomics reveal associations of intratumor bacteria burden with lung cancer cells showing a distinct oncogenic signature Wong-Rolle, A; Dong, Q; Zhu, Y et al. J Immunother Cancer, DOI://10.1136/jitc-2022-004698 (2022)
- Non-synergy of PD-1 blockade with T-cell therapy in solid tumors Davies, JS; Karimipour, F; Zhang, L et al. J Immunother Cancer, DOI://10.1136/jitc-2022-004906 (2022)
- Strong and weak cross-inheritance of substance use disorders in a nationally representative sample Zhang, H; Grant, BF; Hodgkinson, CA et al. Mol Psychiatry, DOI://10.1038/s41380-021-01370-0 (2022)
- Lipid Peroxidation Induced ApoE Receptor-Ligand Disruption as a Unifying Hypothesis Underlying Sporadic Alzheimer's Disease in Humans Ramsden, CE; Keyes, GS; Calzada, E et al. J Alzheimers Dis, DOI://10.3233/JAD-220071 (2022)
- IQ Modulates Coupling Between Diverse Dimensions of Psychopathology in Children and Adolescents Mahony, BW; Tu, D; Rau, S et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2022.06.015 (2022)
- Clonal Hematopoiesis Is Not Significantly Associated with Covid-19 Disease Severity Zhou, Y; Shalhoub, RN; Rogers, SN et al. Blood, DOI://10.1182/blood.2022015721 (2022)
- C3-Symmetric Aromatic Core of Griffithsin Is Essential for Potent Anti-HIV Activity Sun, J; Zhao, G; Bylund, T et al. ACS Chem Biol, DOI://10.1021/acschembio.1c00990 (2022)
- Distinct functions of three chromatin remodelers in activator binding and preinitiation complex assembly Rawal, Y; Qiu, H; Hinnebusch, AG; , PLoS Genet, DOI://10.1371/journal.pgen.1010277 (2022)
- Design principles of PI(4,5)P 2 clustering under protein-free conditions: Specific cation effects and calcium-potassium synergy Han, K; Kim, SH; Venable, RM; Pastor, RW; , Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2202647119 (2022)
- Pruning recurrent neural networks replicates adolescent changes in working memory and reinforcement learning Averbeck, BB Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2121331119 (2022)
- Coding and Noncoding Variation in LRRK2 and Parkinson's Disease Risk Lake, J; Reed, X; Langston, RG et al. Mov Disord, DOI://10.1002/mds.28787 (2022)
- HNRNPH1 destabilizes the G-quadruplex structures formed by G-rich RNA sequences that regulate the alternative splicing of an oncogenic fusion transcript Vo, T; Brownmiller, T; Hall, K et al. Nucleic Acids Res, DOI://10.1093/nar/gkac409 (2022)
- DNA methyltransferase 3B-mediated intra-tumoral heterogeneity and therapeutic targeting in breast cancer recurrence and metastasis So, JY; Yang, HH; Park, WY et al. Mol Cancer Res, DOI://10.1158/1541-7786.MCR-21-0887 (2022)
- Single-Cell Analysis Reveals the Range of Transcriptional States of Circulating Human Neutrophils Wigerblad, G; Cao, Q; Brooks, S et al. J Immunol, DOI://10.4049/jimmunol.2200154 (2022)
- Studies of a mosaic patient with DBA and chimeric mice reveal erythroid cell-extrinsic contributions to erythropoiesis Doty, RT; Fan, X; Young, DJ et al. Blood, DOI://10.1182/blood.2021013507 (2022)
- Hemogen/BRG1 cooperativity modulates promoter and enhancer activation during erythropoiesis Guo, X; Zhao, Y; Kim, J; Dean, A; , Blood, DOI://10.1182/blood.2021014308 (2022)
- A Path-Based Analysis of Infected Cell Line and COVID-19 Patient Transcriptome Reveals Novel Potential Targets and Drugs Against SARS-CoV-2 Agrawal, P; Sambaturu, N; Olgun, G; Hannenhalli, S; , Front Immunol, DOI://10.3389/fimmu.2022.918817 (2022)
- Computational simulations reveal that Abl activity controls cohesiveness of actin networks in growth cones Chandrasekaran, A; Clarke, A; McQueen, P et al. Mol Biol Cell, DOI://10.1091/mbc.E21-11-0535 (2022)
- The structural basis of BCR-ABL recruitment of GRB2 in chronic myelogenous leukemia Liu, Y; Jang, H; Zhang, M et al. Biophys J, DOI://10.1016/j.bpj.2022.05.030 (2022)
- Finite-Size Effects in Simulations of Peptide/Lipid Assembly Jarin, Z; Agolini, O; Pastor, RW; , J Membr Biol, DOI://10.1007/s00232-022-00255-9 (2022)
- Folic acid-mediated fibrosis is driven by C5a receptor 1-mediated activation of kidney myeloid cells Sahu, RK; Xavier, S; Chauss, D et al. Am J Physiol Renal Physiol, DOI://10.1152/ajprenal.00404.2021 (2022)
- Bma-LAD-2, an Intestinal Cell Adhesion Protein, as a Potential Therapeutic Target for Lymphatic Filariasis Flynn, AF; Taylor, RT; Pazgier, ME et al. mBio, DOI://10.1128/mbio.03742-21 (2022)
- Identification of Distinct Inflammatory Programs and Biomarkers in Systemic Juvenile Idiopathic Arthritis and Related Lung Disease by Serum Proteome Analysis Chen, G; Deutsch, GH; Schulert, GS et al. Arthritis Rheumatol, DOI://10.1002/art.42099 (2022)
- BioRED: a rich biomedical relation extraction dataset Luo, L; Lai, PT; Wei, CH et al. Brief Bioinform, DOI://10.1093/bib/bbac282 (2022)
- Global changes in diffusion tensor imaging during acute ischemic stroke and post-stroke cognitive performance Kern, KC; Wright, CB; Leigh, R; , J Cereb Blood Flow Metab, DOI://10.1177/0271678X221101644 (2022)
- Structural and catalytic analyses of the InsP 6 kinase activities of higher plant ITPKs Zong, G; Shears, SB; Wang, H; , FASEB J, DOI://10.1096/fj.202200393R (2022)
- Selective A 3 Adenosine Receptor Antagonist Radioligand for Human and Rodent Species Suresh, RR; Gao, ZG; Salmaso, V et al. ACS Med Chem Lett, DOI://10.1021/acsmedchemlett.1c00685 (2022)
- A molecularly integrated grade for meningioma Driver, J; Hoffman, SE; Tavakol, S et al. Neuro Oncol, DOI://10.1093/neuonc/noab213 (2022)
- Dependence on Bcl6 and Blimp1 drive distinct differentiation of murine memory and follicular helper CD4+ T cells Ciucci, T; Vacchio, MS; Chen, T et al. J Exp Med, DOI://10.1084/jem.20202343 (2022)
- Novel MAPK/AKT-impairing germline NRAS variant identified in a melanoma-prone family Brown, KM; Xu, M; Sargen, M et al. Fam Cancer, DOI://10.1007/s10689-021-00267-9 (2022)
- Reply to Wang et al., "Assessment of the Abundance and Potential Function of Human Papillomavirus Type 16 Circular E7 RNA" Yu, L; Lobanov, A; Zheng, ZM; , mBio, DOI://10.1128/mbio.00758-22 (2022)
- Mucus sialylation determines intestinal host-commensal homeostasis Yao, Y; Kim, G; Shafer, S et al. Cell, DOI://10.1016/j.cell.2022.02.013 (2022)
- P-glycoprotein Mediates Resistance to the Anaplastic Lymphoma Kinase Inhiitor Ensartinib in Cancer Cells Wu, CP; Hung, CY; Murakami, M et al. Cancers (Basel), DOI://10.3390/cancers14092341 (2022)
- Host CLIC4 expression in the tumor microenvironment is essential for breast cancer metastatic competence Sanchez, VC; Yang, HH; Craig-Lucas, A et al. PLoS Genet, DOI://10.1371/journal.pgen.1010271 (2022)
- Non-invasive in situ visualization of the murine cranial vasculature Rosenblum, JS; Cappadona, AJ; Lookian, PP et al. Cell Rep Methods, DOI://10.1016/j.crmeth.2021.100151 (2022)
- ABCA4 c.859-25A>G, a Frequent Palestinian Founder Mutation Affecting the Intron 7 Branchpoint, Is Associated With Early-Onset Stargardt Disease Corradi, Z; Salameh, M; Khan, M et al. Invest Ophthalmol Vis Sci, DOI://10.1167/iovs.63.4.20 (2022)
- Autocrine Canonical Wnt Signaling Primes Noncanonical Signaling through ROR1 in Metastatic Castration-Resistant Prostate Cancer Ma, F; Arai, S; Wang, K et al. Cancer Res, DOI://10.1158/0008-5472.CAN-21-1807 (2022)
- Human constitutive androstane receptor represses liver cancer development and hepatoma cell proliferation by inhibiting erythropoietin signaling Li, Z; Kwon, SM; Li, D et al. J Biol Chem, DOI://10.1016/j.jbc.2022.101885 (2022)
- Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes Lehman, NL; Spassky, N; Sak, M et al. Nat Commun, DOI://10.1038/s41467-022-29302-8 (2022)
- A complete pedigree-based graph workflow for rare candidate variant analysis Markello, C; Huang, C; Rodriguez, A et al. Genome Res, DOI://10.1101/gr.276387.121 (2022)
- Associations of carotid intima media thickness with gene expression in whole blood and genetically predicted gene expression across 48 tissues Castaneda, AB; Petty, LE; Scholz, M et al. Hum Mol Genet, DOI://10.1093/hmg/ddab236 (2022)
- Redefining the Foreign Antigen and Self-Driven Memory CD4+ T-Cell Compartments via Transcriptomic, Phenotypic, and Functional Analyses Kawabe, T; Ciucci, T; Kim, KS et al. Front Immunol, DOI://10.3389/fimmu.2022.870542 (2022)
- Dromedary camel nanobodies broadly neutralize SARS-CoV-2 variants Hong, J; Kwon, HJ; Cachau, R et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2201433119 (2022)
- DNA-PK promotes DNA end resection at DNA double strand breaks in G0 cells Fowler, FC; Chen, BR; Zolnerowich, N et al. Elife, DOI://10.7554/eLife.74700 (2022)
- Cardiovascular disease protein biomarkers are associated with kidney function: The Framingham Heart Study Keshawarz, A; Hwang, SJ; Lee, GY et al. PLoS One, DOI://10.1371/journal.pone.0268293 (2022)
- The CD8α hinge is intrinsically disordered with a dynamic exchange that includes proline cis-trans isomerization Chen, X; Mirazee, JM; Skorupka, KA et al. J Magn Reson, DOI://10.1016/j.jmr.2022.107234 (2022)
- Characterization of Immunogenicity of Malignant Cells with Stemness in Intrahepatic Cholangiocarcinoma by Single-Cell RNA Sequencing Bian, J; Fu, J; Wang, X et al. Stem Cells Int, DOI://10.1155/2022/3558200 (2022)
- Dataset of high-throughput ligand screening against the RNA Packaging Signals regulating Hepatitis B Virus nucleocapsid formation Abulwerdi, F; Fatehi, F; Manfield, IW et al. Data Brief, DOI://10.1016/j.dib.2022.108206 (2022)
- Association of Pathogenic Variants in Hereditary Cancer Genes With Multiple Diseases Zeng, C; Bastarache, LA; Tao, R et al. JAMA Oncol, DOI://10.1001/jamaoncol.2022.0373 (2022)
- A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop Wang, H; Perera, L; Jork, N et al. Nat Commun, DOI://10.1038/s41467-022-29673-y (2022)
- Fully Automated Abdominal CT Biomarkers for Type 2 Diabetes Using Deep Learning Tallam, H; Elton, DC; Lee, S et al. Radiology, DOI://10.1148/radiol.211914 (2022)
- Hierarchical length and sequence preferences establish a single major piRNA 3'-end Stoyko, D; Genzor, P; Haase, AD; , iScience, DOI://10.1016/j.isci.2022.104427 (2022)
- Multiple modes of antigen exposure induce clonotypically diverse epitope-specific CD8+ T cells across multiple tissues in nonhuman primates Simpson, J; Starke, CE; Ortiz, AM et al. PLoS Pathog, DOI://10.1371/journal.ppat.1010611 (2022)
- Butyrate administration is not sufficient to improve immune reconstitution in antiretroviral-treated SIV-infected macaques Ortiz, AM; Simpson, J; Langner, CA et al. Sci Rep, DOI://10.1038/s41598-022-11122-x (2022)
- Functional Heterogeneity of Cell Populations Increases Robustness of Pacemaker Function in a Numerical Model of the Sinoatrial Node Tissue Maltsev, AV; Stern, MD; Lakatta, EG; Maltsev, VA; , Front Physiol, DOI://10.3389/fphys.2022.845634 (2022)
- Sex-specific placental gene expression signatures of small for gestational age at birth Chatterjee, S; Zeng, X; Ouidir, M et al. Placenta, DOI://10.1016/j.placenta.2022.03.004 (2022)
- Bayesian analysis of dynamic phosphoproteomic data identifies protein kinases mediating GPCR responses Leo, KT; Chou, CL; Yang, CR et al. Cell Commun Signal, DOI://10.1186/s12964-022-00892-6 (2022)
- Postmitotic G1 phase survivin drives mitogen-independent cell division of B lymphocytes Singh, A; Spitzer, MH; Joy, JP et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2115567119 (2022)
- Acquired Disorder and Asymmetry in a Domain-Swapped Model for γ-Crystallin Aggregation Sagar, V; Wistow, G; , J Mol Biol, DOI://10.1016/j.jmb.2022.167559 (2022)
- Plasticity in structure and assembly of SARS-CoV-2 nucleocapsid protein Zhao, H; Nguyen, A; Wu, D et al. PNAS Nexus, DOI://10.1093/pnasnexus/pgac049 (2022)
- Predominant Founder Effect among Recurrent Pathogenic Variants for an X-Linked Disorder Bender, C; Woo, EG; Guan, B et al. Genes (Basel), DOI://10.3390/genes13040675 (2022)
- Computational modeling of threat learning reveals links with anxiety and neuroanatomy in humans Abend, R; Burk, D; Ruiz, SG et al. Elife, DOI://10.7554/eLife.66169 (2022)
- Cryo-EM structure of anchorless RML prion reveals variations in shared motifs between distinct strains Hoyt, F; Standke, HG; Artikis, E et al. Nat Commun, DOI://10.1038/s41467-022-30458-6 (2022)
- On-scalp magnetocorticography with optically pumped magnetometers: Simulated performance in resolving simultaneous sources Nugent, AC; Benitez Andonegui, A; Holroyd, T; Robinson, SE; , Neuroimage Rep, DOI://10.1016/j.ynirp.2022.100093 (2022)
- Patagonian sheepdog: Genomic analyses trace the footprints of extinct UK herding dogs to South America Barrios, N; González-Lagos, C; Dreger, DL et al. PLoS Genet, DOI://10.1371/journal.pgen.1010160 (2022)
- APOE gene region methylation is associated with cognitive performance in middle-aged urban adults Shen, B; Hernandez, DG; Chitrala, KN et al. Neurobiol Aging, DOI://10.1016/j.neurobiolaging.2022.03.010 (2022)
- Checkpoint Inhibitors Modulate Plasticity of Innate Lymphoid Cells in Peripheral Blood of Patients With Hepatocellular Carcinoma Heinrich, B; Ruf, B; Subramanyam, V et al. Front Immunol, DOI://10.3389/fimmu.2022.849958 (2022)
- Unraveling the Treatment Effect of Baricitinib on Clinical Progression and Resource Utilization in Hospitalized COVID-19 Patients: Secondary Analysis of the Adaptive COVID-19 Treatment Randomized Trial-2 Fintzi, J; Bonnett, T; Tebas, P et al. Open Forum Infect Dis, DOI://10.1093/ofid/ofac219 (2022)
- Scoping review and classification of deep learning in medical genetics Ledgister Hanchard, SE; Dwyer, MC; Liu, S et al. Genet Med, DOI://10.1016/j.gim.2022.04.025 (2022)
- A Genome-First Approach to Estimate Prevalence of Germline Pathogenic Variants and Risk of Pancreatic Cancer in Select Cancer Susceptibility Genes Astiazaran-Symonds, E; Kim, J; Haley, JS et al. Cancers (Basel), DOI://10.3390/cancers14133257 (2022)
- A dual-activity topoisomerase complex regulates mRNA translation and turnover Su, S; Xue, Y; Sharov, A et al. Nucleic Acids Res, DOI://10.1093/nar/gkac538 (2022)
- Durable response in a patient with recurrent respiratory papillomatosis treated with immune checkpoint blockade Bai, K; Norberg, SM; Sievers, C et al. Head Neck, DOI://10.1002/hed.27144 (2022)
- Question-aware transformer models for consumer health question summarization Yadav, S; Gupta, D; Abacha, AB; Demner-Fushman, D; , J Biomed Inform, DOI://10.1016/j.jbi.2022.104040 (2022)
- Dentithecamides A-H, Diacylated Zoanthoxanthin Derivatives with PAX3-FOXO1 Inhibitory Activity from the Hydroid Dentitheca habereri Jiang, W; Tian, X; Wang, D et al. J Nat Prod, DOI://10.1021/acs.jnatprod.2c00246 (2022)
- GRN Mutations Are Associated with Lewy Body Dementia Reho, P; Koga, S; Shah, Z et al. Mov Disord, DOI://10.1002/mds.29144 (2022)
- DiffChIPL: A differential peak analysis method for high throughput sequencing data with biological replicates based on limma Chen, Y; Chen, S; Lei, EP; , Bioinformatics, DOI://10.1093/bioinformatics/btac498 (2022)
- Translation of cytoplasmic UBA1 contributes to VEXAS syndrome pathogenesis Ferrada, MA; Savic, S; Ospina Cardona, D et al. Blood, DOI://10.1182/blood.2022016985 (2022)
- Dysregulation of Hepatitis B Virus Nucleocapsid Assembly in vitro by RNA-binding Small Ligands Patel, N; Abulwerdi, F; Fatehi, F et al. J Mol Biol, DOI://10.1016/j.jmb.2022.167557 (2022)
- Prior Vaccination Exceeds Prior Infection in Eliciting Innate and Humoral Immune Responses in Omicron Infected Outpatients Lee, HK; Knabl, L; Walter, M et al. Front Immunol, DOI://10.3389/fimmu.2022.916686 (2022)
- Many dissimilar NusG protein domains switch between α-helix and β-sheet folds Porter, LL; Kim, AK; Rimal, S et al. Nat Commun, DOI://10.1038/s41467-022-31532-9 (2022)
- Systematic identification of molecular mediators of interspecies sensing in a community of two frequently coinfecting bacterial pathogens Zarrella, TM; Khare, A; , PLoS Biol, DOI://10.1371/journal.pbio.3001679 (2022)
- Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma Lee, PC; Klaeger, S; Le, PM et al. J Clin Invest, DOI://10.1172/JCI151666 (2022)
- Putative Host-Derived Insertions in the Genomes of Circulating SARS-CoV-2 Variants Yang, Y; Dufault-Thompson, K; Salgado Fontenele, R; Jiang, X; , mSystems, DOI://10.1128/msystems.00179-22 (2022)
- Genetic evaluation of dementia with Lewy bodies implicates distinct disease subgroups Kaivola, K; Shah, Z; Chia, R et al. Brain, DOI://10.1093/brain/awab402 (2022)
- Sorting out Parkinson's disease: one cell at a time Lin, HP; Narendra, DP; , Brain, DOI://10.1093/brain/awac071 (2022)
- Interrogating RNA-Small Molecule Interactions with Structure Probing and Artificial Intelligence-Augmented Molecular Simulations Wang, Y; Parmar, S; Schneekloth, JS; Tiwary, P; , ACS Cent Sci, DOI://10.1021/acscentsci.2c00149 (2022)
- Long-read mapping to repetitive reference sequences using Winnowmap2 Jain, C; Rhie, A; Hansen, NF et al. Nat Methods, DOI://10.1038/s41592-022-01457-8 (2022)
- Copper-Binding Domain Variation in a Novel Murine Lysyl Oxidase Model Produces Structurally Inferior Aortic Elastic Fibers Whose Failure Is Modified by Age, Sex, and Blood Pressure Tsang, KM; Knutsen, RH; Billington, CJ et al. Int J Mol Sci, DOI://10.3390/ijms23126749 (2022)
- Enhanced neoepitope-specific immunity following neoadjuvant PD-L1 and TGF-b blockade in HPV-unrelated head and neck cancer Redman, JM; Friedman, J; Robbins, Y et al. J Clin Invest, DOI://10.1172/JCI161400 (2022)
- An 8-Gene Signature for Classifying Major Subtypes of Non-Small-Cell Lung Cancer Hamaneh, M; Yu, YK; , Cancer Inform, DOI://10.1177/11769351221100718 (2022)
- Cross-sectional and Longitudinal Associations of Anxiety and Irritability With Adolescents' Neural Responses to Cognitive Conflict Cardinale, EM; Bezek, J; Morales, S et al. Biol Psychiatry Cogn Neurosci Neuroimaging, DOI://10.1016/j.bpsc.2022.03.007 (2022)
- Investigating the genetic architecture of eye colour in a Canadian cohort Lona-Durazo, F; Thakur, R; Pairo-Castineira, E et al. iScience, DOI://10.1016/j.isci.2022.104485 (2022)
- Macaque Clonal Hematopoiesis Model Demonstrates Expansion of TET2-Disrupted Clones and Utility for Testing Interventions Shin, TH; Zhou, Y; Chen, S et al. Blood, DOI://10.1182/blood.2021014875 (2022)
- A cellular and molecular analysis of SoxB-driven neurogenesis in a cnidarian Chrysostomou, E; Flici, H; Gornik, SG et al. Elife, DOI://10.7554/eLife.78793 (2022)
- Classification of Functional Movement Disorders with Resting-State Functional Magnetic Resonance Imaging Waugh, RE; Parker, JA; Hallett, M; Horovitz, SG; , Brain Connect, DOI://10.1089/brain.2022.0001 (2022)
- Isha is a su(Hw) mRNA-binding protein required for gypsy insulator function Bag, I; Chen, Y; D'Orazio, K et al. G3 (Bethesda), DOI://10.1093/g3journal/jkac152 (2022)
- Donor-derived cell-free DNA as a composite marker of acute lung allograft dysfunction in clinical care Keller, M; Sun, J; Mutebi, C et al. J Heart Lung Transplant, DOI://10.1016/j.healun.2021.12.009 (2022)
- GPR15L is an epithelial inflammation-derived pruritogen Tseng, PY; Hoon, MA; , Sci Adv, DOI://10.1126/sciadv.abm7342 (2022)
- DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity Roy, R; Ramamoorthy, S; Shapiro, BD et al. Immunity, DOI://10.1016/j.immuni.2022.05.006 (2022)
- Antisense transcription from lentiviral gene targeting linked to an integrated stress response in colorectal cancer cells Ha, T; DiPrima, M; Koparde, V et al. Mol Ther Nucleic Acids, DOI://10.1016/j.omtn.2022.05.029 (2022)
- Notes from the Field: VEXAS Syndrome and Disease Taxonomy in Rheumatology Grayson, PC; Beck, DB; Ferrada, MA et al. Arthritis Rheumatol, DOI://10.1002/art.42258 (2022)
- Functional characterization of a novel p.Ser76Thr variant in IGFBP4 that associates with body mass index in American Indians Muller, YL; Saporito, M; Day, S et al. Eur J Hum Genet, DOI://10.1038/s41431-022-01129-3 (2022)
- Prostate-Specific Membrane Antigen Is a Biomarker for Residual Disease following Neoadjuvant Intense Androgen Deprivation Therapy in Prostate Cancer Bright, JR; Lis, RT; Ku, AT et al. J Urol, DOI://10.1097/JU.0000000000002492 (2022)
- High-Frequency Transcranial Magnetic Stimulation Combined With Functional Magnetic Resonance Imaging Reveals Distinct Activation Patterns Associated With Different Dorsolateral Prefrontal Cortex Stimulation Sites Caparelli, EC; Schleyer, B; Zhai, T et al. Neuromodulation, DOI://10.1016/j.neurom.2022.03.002 (2022)
- Additive genetic effect of GCKR, G6PC2, and SLC30A8 variants on fasting glucose levels and risk of type 2 diabetes Chen, G; Shriner, D; Zhang, J et al. PLoS One, DOI://10.1371/journal.pone.0269378 (2022)
- Immune Determinants of the Association between Tumor Mutational Burden and Immunotherapy Response across Cancer Types Sinha, N; Sinha, S; Valero, C et al. Cancer Res, DOI://10.1158/0008-5472.CAN-21-2542 (2022)
- Lesion size and shape in central vein sign assessment for multiple sclerosis diagnosis: An in vivo and postmortem MRI study Al-Louzi, O; Manukyan, S; Donadieu, M et al. Mult Scler, DOI://10.1177/13524585221097560 (2022)
- Heterologous ChAdOx1-BNT162b2 vaccination in Korean cohort induces robust immune and antibody responses that includes Omicron Lee, HK; Go, J; Sung, H et al. iScience, DOI://10.1016/j.isci.2022.104473 (2022)
- Genetically programmed alternative splicing of NEMO mediates an autoinflammatory disease phenotype Lee, Y; Wessel, AW; Xu, J et al. J Clin Invest, DOI://10.1172/JCI128808 (2022)
- Impact of the methylation classifier and ancillary methods on CNS tumor diagnostics Wu, Z; Abdullaev, Z; Pratt, D et al. Neuro Oncol, DOI://10.1093/neuonc/noab227 (2022)
- Development of Aging-Related Emphysematous and Lymphoma-Like Lesions is Enhanced by the Lack of Secretoglobin 3A2 in Mouse Lungs Kurotani, R; Kurumazuka, A; Sakahara, S et al. Int J Chron Obstruct Pulmon Dis, DOI://10.2147/COPD.S330170 (2022)
- Neuropeptides in Rhipicephalus microplus and other hard ticks Waldman, J; Xavier, MA; Vieira, LR et al. Ticks Tick Borne Dis, DOI://10.1016/j.ttbdis.2022.101910 (2022)
- Intestinal inflammation alters the antigen-specific immune response to a skin commensal Merana, GR; Dwyer, LR; Dhariwala, MO et al. Cell Rep, DOI://10.1016/j.celrep.2022.110891 (2022)
- Identification of Antibiotic Resistance Proteins via MiCId's Augmented Workflow. A Mass Spectrometry-Based Proteomics Approach Alves, G; Ogurtsov, A; Karlsson, R et al. J Am Soc Mass Spectrom, DOI://10.1021/jasms.1c00347 (2022)
- Variegation of autism related traits across seven neurogenetic disorders Lee, NR; Niu, X; Zhang, F et al. Transl Psychiatry, DOI://10.1038/s41398-022-01895-0 (2022)
- Human lymph node immune dynamics as driver of vaccine efficacy: an understudied aspect of immune responses Moysi, E; Paris, RM; Le Grand, R et al. Expert Rev Vaccines, DOI://10.1080/14760584.2022.2045198 (2022)
- AlphaFold2 fails to predict protein fold switching Chakravarty, D; Porter, LL; , Protein Sci, DOI://10.1002/pro.4353 (2022)
- In situ cryo-electron tomography reveals local cellular machineries for axon branch development Nedozralova, H; Basnet, N; Ibiricu, I et al. J Cell Biol, DOI://10.1083/jcb.202106086 (2022)
- High-grade glioma with pleomorphic and pseudopapillary features (HPAP): a proposed type of circumscribed glioma in adults harboring frequent TP53 mutations and recurrent monosomy 13 Pratt, D; Abdullaev, Z; Papanicolau-Sengos, A et al. Acta Neuropathol, DOI://10.1007/s00401-022-02404-9 (2022)
- A missense variant Arg611Cys in LIPE which encodes hormone sensitive lipase decreases lipolysis and increases risk of type 2 diabetes in American Indians Muller, YL; Sutherland, J; Nair, AK et al. Diabetes Metab Res Rev, DOI://10.1002/dmrr.3504 (2022)
- Boosting NAD+ blunts TLR4-induced type I IFN in control and systemic lupus erythematosus monocytes Wu, J; Singh, K; Lin, A et al. J Clin Invest, DOI://10.1172/JCI139828 (2022)
- Context-dependent amygdala-prefrontal connectivity during the dot-probe task varies by irritability and attention bias to angry faces Naim, R; Haller, SP; Linke, JO et al. Neuropsychopharmacology, DOI://10.1038/s41386-022-01307-3 (2022)
- Functional editing of endogenous genes through rapid selection of cell pools (Rapid generation of endogenously tagged genes in Drosophila ovarian somatic sheath cells) Meng, Q; Stoyko, D; Andrews, CM et al. Nucleic Acids Res, DOI://10.1093/nar/gkac448 (2022)
- Computational modeling of mitochondrial K+- and H+-driven ATP synthesis Cortassa, S; Aon, MA; Juhaszova, M et al. J Mol Cell Cardiol, DOI://10.1016/j.yjmcc.2021.12.005 (2022)
- Integrated Multiomics, Bioinformatics, and Computational Modeling Approaches to Central Metabolism in Organs Cortassa, S; Villon, P; Sollott, SJ; Aon, MA; , Methods Mol Biol, DOI://10.1007/978-1-0716-1831-8_7 (2022)
- Systems Biology of the Vasopressin V2 Receptor: New Tools for Discovery of Molecular Actions of a GPCR Chen, L; Jung, HJ; Datta, A et al. Annu Rev Pharmacol Toxicol, DOI://10.1146/annurev-pharmtox-052120-011012 (2022)
- Draft Reference Genome Sequence of Corynebacterium mastitidis RC, an Ocular Commensal, Isolated from Mouse Conjunctiva Nagarajan, V; St Leger, AJ; Zhang, A et al. Microbiol Resour Announc, DOI://10.1128/mra.00187-22 (2022)
- Rare and common variants in ROM1 and PRPH2 genes trans-modify Stargardt/ABCA4 disease Zernant, J; Lee, W; Wang, J et al. PLoS Genet, DOI://10.1371/journal.pgen.1010129 (2022)
- Structural basis for catalyzed assembly of the Sonic hedgehog-Patched1 signaling complex Huang, P; Wierbowski, BM; Lian, T et al. Dev Cell, DOI://10.1016/j.devcel.2022.02.008 (2022)
- Diagnostic and Prognostic Implications of GNAS Inactivation in Sonic Hedgehog-Activated Medulloblastoma: Case Report with Comprehensive Molecular Profiling and Review of Literature Goode, E; Montoya, L; Graham, E et al. JCO Precis Oncol, DOI://10.1200/PO.21.00403 (2022)
- Differential ion dehydration energetics explains selectivity in the non-canonical lysosomal K + channel TMEM175 Oh, S; Marinelli, F; Zhou, W et al. Elife, DOI://10.7554/eLife.75122 (2022)
- Predicting cancer prognosis and drug response from the tumor microbiome Hermida, LC; Gertz, EM; Ruppin, E; , Nat Commun, DOI://10.1038/s41467-022-30512-3 (2022)
- A comprehensive evaluation of the potential binding poses of fentanyl and its analogs at the µ-opioid receptor Xie, B; Goldberg, A; Shi, L; , Comput Struct Biotechnol J, DOI://10.1016/j.csbj.2022.05.013 (2022)
- SARS-CoV-2 introductions and early dynamics of the epidemic in Portugal Borges, V; Isidro, J; Trovão, NS et al. Commun Med (Lond), DOI://10.1038/s43856-022-00072-0 (2022)
- Synthetic lethality-based prediction of anti-SARS-CoV-2 targets Pal, LR; Cheng, K; Nair, NU et al. iScience, DOI://10.1016/j.isci.2022.104311 (2022)
- Coxiella Endosymbiont of Rhipicephalus microplus Modulates Tick Physiology With a Major Impact in Blood Feeding Capacity Guizzo, MG; Tirloni, L; Gonzalez, SA et al. Front Microbiol, DOI://10.3389/fmicb.2022.868575 (2022)
- Obtaining QM/MM binding free energies in the SAMPL8 drugs of abuse challenge: indirect approaches Hudson, PS; Aviat, F; Meana-Pañeda, R et al. J Comput Aided Mol Des, DOI://10.1007/s10822-022-00443-8 (2022)
- Conformational spread drives the evolution of the calcium-calmodulin protein kinase II Khan, S Sci Rep, DOI://10.1038/s41598-022-12090-y (2022)
- GraphVAMPNet, using graph neural networks and variational approach to Markov processes for dynamical modeling of biomolecules Ghorbani, M; Prasad, S; Klauda, JB; Brooks, BR; , J Chem Phys, DOI://10.1063/5.0085607 (2022)
- GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision Asher, WB; Terry, DS; Gregorio, GGA et al. Cell, DOI://10.1016/j.cell.2022.03.042 (2022)
- Drugsniffer: An Open Source Workflow for Virtually Screening Billions of Molecules for Binding Affinity to Protein Targets Venkatraman, V; Colligan, TH; Lesica, GT et al. Front Pharmacol, DOI://10.3389/fphar.2022.874746 (2022)
- Serum proteomics links suppression of tumor immunity to ancestry and lethal prostate cancer Minas, TZ; Candia, J; Dorsey, TH et al. Nat Commun, DOI://10.1038/s41467-022-29235-2 (2022)
- DNA methylation analysis of glioblastomas harboring FGFR3-TACC3 fusions identifies a methylation subclass with better patient survival Wu, Z; Lopes Abath Neto, O; Bale, TA et al. Acta Neuropathol, DOI://10.1007/s00401-022-02430-7 (2022)
- Structural characterization of the Myxococcus xanthus encapsulin and ferritin-like cargo system gives insight into its iron storage mechanism Eren, E; Wang, B; Winkler, DC et al. Structure, DOI://10.1016/j.str.2022.01.008 (2022)
- Flexible pri-miRNA structures enable tunable production of 5' isomiRs Bofill-De Ros, X; Hong, Z; Birkenfeld, B et al. RNA Biol, DOI://10.1080/15476286.2022.2025680 (2022)
- A phenotypic signature that identifies neoantigen-reactive T cells in fresh human lung cancers Hanada, KI; Zhao, C; Gil-Hoyos, R et al. Cancer Cell, DOI://10.1016/j.ccell.2022.03.012 (2022)
- Protonation-Dependent Sequencing of 5-Formylcytidine in RNA Link, CN; Thalalla Gamage, S; Gallimore, D et al. Biochemistry, DOI://10.1021/acs.biochem.1c00761 (2022)
- Phylogenomic analysis of the diversity of graspetides and proteins involved in their biosynthesis Makarova, KS; Blackburne, B; Wolf, YI et al. Biol Direct, DOI://10.1186/s13062-022-00320-2 (2022)
- Immune transcriptome and antibody response in adult-onset Still's disease with mild flare following administration of mRNA vaccine BNT162b2 Knabl, L; Lee, HK; Walter, M et al. Rheumatology (Oxford), DOI://10.1093/rheumatology/keac281 (2022)
- DDX58(RIG-I)-related disease is associated with tissue-specific interferon pathway activation Prasov, L; Bohnsack, BL; El Husny, AS et al. J Med Genet, DOI://10.1136/jmedgenet-2020-107447 (2022)
- The mechanism of activation of MEK1 by B-Raf and KSR1 Maloney, RC; Zhang, M; Liu, Y et al. Cell Mol Life Sci, DOI://10.1007/s00018-022-04296-0 (2022)
- Placental multi-omics integration identifies candidate functional genes for birthweight Tekola-Ayele, F; Zeng, X; Chatterjee, S et al. Nat Commun, DOI://10.1038/s41467-022-30007-1 (2022)
- Increasing efficiency and reducing bias when assessing HPV vaccination efficacy by using nontargeted HPV strains Etievant, L; Sampson, JN; Gail, MH; , Biometrics, DOI://10.1111/biom.13663 (2022)
- Modeling Androgen Deprivation Therapy-Induced Prostate Cancer Dormancy and Its Clinical Implications Dong, X; Xue, H; Mo, F et al. Mol Cancer Res, DOI://10.1158/1541-7786.MCR-21-1037 (2022)
- Retinal pigment epithelium-specific CLIC4 mutant is a mouse model of dry age-related macular degeneration Chuang, JZ; Yang, N; Nakajima, N et al. Nat Commun, DOI://10.1038/s41467-021-27935-9 (2022)
- A T cell resilience model associated with response to immunotherapy in multiple tumor types Zhang, Y; Trang, V; Palmer, DC et al. Nat Med, DOI://10.1038/s41591-022-01799-y (2022)
- Inactivation of axon guidance molecule netrin-1 in human colorectal cancer by an epigenetic mechanism Nakayama, H; Ohnuki, H; Nakahara, M et al. Biochem Biophys Res Commun, DOI://10.1016/j.bbrc.2022.04.069 (2022)
- Urine Single-Cell RNA Sequencing in Focal Segmental Glomerulosclerosis Reveals Inflammatory Signatures Latt, KZ; Heymann, J; Jessee, JH et al. Kidney Int Rep, DOI://10.1016/j.ekir.2021.11.005 (2022)
- Selective Recognition of Carbohydrate Antigens by Germline Antibodies Isolated from AID Knockout Mice DeLaitsch, AT; Pridgen, JR; Tytla, A et al. J Am Chem Soc, DOI://10.1021/jacs.1c12745 (2022)
- Transposable element landscapes in aging Drosophila Yang, N; Srivastav, SP; Rahman, R et al. PLoS Genet, DOI://10.1371/journal.pgen.1010024 (2022)
- Neural Networks for Classification and Image Generation of Aging in Genetic Syndromes Duong D; Hu P.; et al Front Genet., 10.3389/fgene.2022.864092 (2022)
- BNT162b2 vaccination enhances interferon-JAK-STAT-regulated antiviral programs in COVID-19 patients infected with the SARS-CoV-2 Beta variant Knabl, L; Lee, HK; Wieser, M et al. Commun Med (Lond), DOI://10.1038/s43856-022-00083-x (2022)
- Evolutionary history and introduction of SARS-CoV-2 Alpha VOC/B.1.1.7 in Pakistan through international travelers Nasir, A; Bukhari, AR; Trovão, NS et al. Virus Evol, DOI://10.1093/ve/veac020 (2022)
- Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci Yin, X; Chan, LS; Bose, D et al. Nat Commun, DOI://10.1038/s41467-022-29143-5 (2022)
- Simultaneous Quantification of H2O2 and Organic Hydroperoxides by 1H NMR Spectroscopy Kakeshpour, T; Bax, A; , Anal Chem, DOI://10.1021/acs.analchem.2c00264 (2022)
- Synthesis and Effect of Conformationally Locked Carbocyclic Guanine Nucleotides on Dynamin Toti, KS; Jimah, JR; Salmaso, V et al. Biomolecules, DOI://10.3390/biom12040584 (2022)
- Estimation of multiple ordered ROC curves using placement values Ghosal, S; Grantz, KL; Chen, Z; , Stat Methods Med Res, DOI://10.1177/09622802221094940 (2022)
- Utilizing patient information to identify subtype heterogeneity of cancer driver genes Wu, HH; Hua, X; Shi, J et al. Stat Methods Med Res, DOI://10.1177/09622802211055854 (2022)
- Lysosomal exocytosis of HSP70 stimulates monocytic BMP6 expression in Sjögren's syndrome Mo, YQ; Nakamura, H; Tanaka, T et al. J Clin Invest, DOI://10.1172/JCI152780 (2022)
- Heterogeneity of neuroendocrine transcriptional states in metastatic small cell lung cancers and patient-derived models Lissa, D; Takahashi, N; Desai, P et al. Nat Commun, DOI://10.1038/s41467-022-29517-9 (2022)
- Autophosphorylation transforms DNA-PK from protecting to processing DNA ends Liu, L; Chen, X; Li, J et al. Mol Cell, DOI://10.1016/j.molcel.2021.11.025 (2022)
- H3K27ac nucleosomes facilitate HMGN localization at regulatory sites to modulate chromatin binding of transcription factors Zhang, S; Postnikov, Y; Lobanov, A et al. Commun Biol, DOI://10.1038/s42003-022-03099-0 (2022)
- The transcription factor LRF promotes integrin β7 expression by and gut homing of CD8αα + intraepithelial lymphocyte precursors Nie, J; Carpenter, AC; Chopp, LB et al. Nat Immunol, DOI://10.1038/s41590-022-01161-x (2022)
- Oncogenic lncRNAs alter epigenetic memory at a fragile chromosomal site in human cancer cells Arunkumar, G; Baek, S; Sturgill, D et al. Sci Adv, DOI://10.1126/sciadv.abl5621 (2022)
- Dosage compensation in Bombyx mori is achieved by partial repression of both Z chromosomes in males Rosin, LF; Chen, D; Chen, Y; Lei, EP; , Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2113374119 (2022)
- Integrating cultivation and metagenomics for a multi-kingdom view of skin microbiome diversity and functions Saheb Kashaf, S; Proctor, DM; Deming, C et al. Nat Microbiol, DOI://10.1038/s41564-021-01011-w (2022)
- Artificial intelligence approaches to human-microbiome protein-protein interactions Lim, H; Cankara, F; Tsai, CJ et al. Curr Opin Struct Biol, DOI://10.1016/j.sbi.2022.102328 (2022)
- Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter Thaker, TM; Mishra, S; Zhou, W et al. Nat Chem Biol, DOI://10.1038/s41589-021-00936-x (2022)
- Patterns of Crystallin Gene Expression in Differentiation State Specific Regions of the Embryonic Chicken Lens Ma, Z; Chauss, D; Disatham, J et al. Invest Ophthalmol Vis Sci, DOI://10.1167/iovs.63.4.8 (2022)
- SUITOR: Selecting the number of mutational signatures through cross-validation Lee, D; Wang, D; Yang, XR et al. PLoS Comput Biol, DOI://10.1371/journal.pcbi.1009309 (2022)
- Reliability of task-evoked neural activation during face-emotion paradigms: Effects of scanner and psychological processes Haller, SP; Chen, G; Kitt, ER et al. Hum Brain Mapp, DOI://10.1002/hbm.25723 (2022)
- Modified eQTL and Somatic DNA Segment Alterations in Esophageal Squamous Cell Carcinoma for Genes Related to Immunity, DNA Repair, and Inflammation Yang, HH; Liu, H; Hu, N et al. Cancers (Basel), DOI://10.3390/cancers14071629 (2022)
- ATP Synthase K+- and H+-fluxes Drive ATP Synthesis and Enable Mitochondrial K+-Uniporter Function: II. Ion and ATP Synthase Flux Regulation Juhaszova, M; Kobrinsky, E; Zorov, DB et al. Function (Oxf), DOI://10.1093/function/zqac001 (2022)
- ATP Synthase K+- and H+-Fluxes Drive ATP Synthesis and Enable Mitochondrial K+-Uniporter Function: I. Characterization of Ion Fluxes Juhaszova, M; Kobrinsky, E; Zorov, DB et al. Function (Oxf), DOI://10.1093/function/zqab065 (2022)
- Long-read sequencing reveals complex patterns of wraparound transcription in polyomaviruses Nomburg, J; Zou, W; Frost, TC et al. PLoS Pathog, DOI://10.1371/journal.ppat.1010401 (2022)
- HiCRes: a computational method to estimate and predict the genomic resolution of Hi-C libraries Marchal, C; Singh, N; Corso-Díaz, X; Swaroop, A; , Nucleic Acids Res, DOI://10.1093/nar/gkab1235 (2022)
- Modulation of free energy landscapes as a strategy for the design of antimicrobial peptides Hassan, SA; Steinbach, PJ; , J Biol Phys, DOI://10.1007/s10867-022-09605-z (2022)
- mRNA vaccination in octogenarians 15 and 20 months after recovery from COVID-19 elicits robust immune and antibody responses that include Omicron Lee, HK; Knabl, L; Moliva, JI et al. Cell Rep, DOI://10.1016/j.celrep.2022.110680 (2022)
- A deep learning system for automated kidney stone detection and volumetric segmentation on noncontrast CT scans Elton, DC; Turkbey, EB; Pickhardt, PJ; Summers, RM; , Med Phys, DOI://10.1002/mp.15518 (2022)
- The glucocorticoid receptor associates with the cohesin loader NIPBL to promote long-range gene regulation Rinaldi, L; Fettweis, G; Kim, S et al. Sci Adv, DOI://10.1126/sciadv.abj8360 (2022)
- Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers Lowery, FJ; Krishna, S; Yossef, R et al. Science, DOI://10.1126/science.abl5447 (2022)
- Virtual Screening for the Discovery of Microbiome β-Glucuronidase Inhibitors to Alleviate Cancer Drug Toxicity Challa, AP; Hu, X; Zhang, YQ et al. J Chem Inf Model, DOI://10.1021/acs.jcim.1c01414 (2022)
- Examination of Genetic Susceptibility in Radiation-Associated Meningioma Pemov, A; Kim, J; Jones, K et al. Radiat Res, DOI://10.1667/RADE-21-00035.1 (2022)
- The progressive spectral signal-to-noise ratio of cryo-electron micrograph movies as a tool to assess quality and radiation damage Heymann, JB Comput Methods Programs Biomed, DOI://10.1016/j.cmpb.2022.106799 (2022)
- Cure of syngeneic carcinomas with targeted IL-12 through obligate reprogramming of lymphoid and myeloid immunity Hong, Y; Robbins, Y; Yang, X et al. JCI Insight, DOI://10.1172/jci.insight.157448 (2022)
- The amyloid concentric β-barrel hypothesis: Models of synuclein oligomers, annular protofibrils, lipoproteins, and transmembrane channels Durell, SR; Guy, HR; , Proteins, DOI://10.1002/prot.26249 (2022)
- TMPRSS2-ERG promotes the initiation of prostate cancer by suppressing oncogene-induced senescence Fang, L; Li, D; Yin, J et al. Cancer Gene Ther, DOI://10.1038/s41417-022-00454-5 (2022)
- Combining selinexor with alisertib to target the p53 pathway in neuroblastoma Nguyen, R; Wang, H; Sun, M et al. Neoplasia, DOI://10.1016/j.neo.2022.100776 (2022)
- Detailed mapping of behavior reveals the formation of prelimbic neural ensembles across operant learning Zhang, Y; Denman, AJ; Liang, B et al. Neuron, DOI://10.1016/j.neuron.2021.11.022 (2022)
- The posterior cingulate cortex reflects the impact of anxiety on drift rates during cognitive processing Gorka, AX; Philips, RT; Torrisi, S et al. Biol Psychiatry Cogn Neurosci Neuroimaging, DOI://10.1016/j.bpsc.2022.03.010 (2022)
- Understanding immunity in a tissue-centric context: Combining novel imaging methods and mathematics to extract new insights into function and dysfunction Germain, RN; Radtke, AJ; Thakur, N et al. Immunol Rev, DOI://10.1111/imr.13052 (2022)
- Yearlong COVID-19 Infection Reveals Within-Host Evolution of SARS-CoV-2 in a Patient With B-Cell Depletion Nussenblatt, V; Roder, AE; Das, S et al. J Infect Dis, DOI://10.1093/infdis/jiab622 (2022)
- Imaging the immune system redux Germain, RN Immunol Rev, DOI://10.1111/imr.13063 (2022)
- Structure of the Shaker Kv channel and mechanism of slow C-type inactivation Tan, XF; Bae, C; Stix, R et al. Sci Adv, DOI://10.1126/sciadv.abm7814 (2022)
- Merfin: improved variant filtering, assembly evaluation and polishing via k-mer validation Formenti, G; Rhie, A; Walenz, BP et al. Nat Methods, DOI://10.1038/s41592-022-01445-y (2022)
- The complete sequence of a human genome Nurk, S; Koren, S; Rhie, A et al. Science, DOI://10.1126/science.abj6987 (2022)
- From telomere to telomere: The transcriptional and epigenetic state of human repeat elements Hoyt, SJ; Storer, JM; Hartley, GA et al. Science, DOI://10.1126/science.abk3112 (2022)
- Epigenetic patterns in a complete human genome Gershman, A; Sauria, MEG; Guitart, X et al. Science, DOI://10.1126/science.abj5089 (2022)
- Chasing perfection: validation and polishing strategies for telomere-to-telomere genome assemblies McCartney AM, Shafin K, Alonge M et al Nat. Methods, 10.1038/s41592-022-01440-3 (2022)
- Segmental duplications and their variation in a complete human genome Vollger, MR; Guitart, X; Dishuck, PC et al. Science, DOI://10.1126/science.abj6965 (2022)
- Complete genomic and epigenetic maps of human centromeres Altemose, N; Logsdon, GA; Bzikadze, AV et al. Science, DOI://10.1126/science.abl4178 (2022)
- A complete reference genome improves analysis of human genetic variation Aganezov, S; Yan, SM; Soto, DC et al. Science, DOI://10.1126/science.abl3533 (2022)
- Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain Lee, DR; Rhodes, C; Mitra, A et al. Elife, DOI://10.7554/eLife.71864 (2022)
- Transcriptomic analysis of human sensory neurons in painful diabetic neuropathy reveals inflammation and neuronal loss Hall, BE; Macdonald, E; Cassidy, M et al. Sci Rep, DOI://10.1038/s41598-022-08100-8 (2022)
- The genome of the zebra mussel, Dreissena polymorpha: a resource for comparative genomics, invasion genetics, and biocontrol McCartney, MA; Auch, B; Kono, T et al. G3 (Bethesda), DOI://10.1093/g3journal/jkab423 (2022)
- Epstein-Barr Virus in Burkitt Lymphoma in Africa Reveals a Limited Set of Whole Genome and LMP-1 Sequence Patterns: Analysis of Archival Datasets and Field Samples From Uganda, Tanzania, and Kenya Liao, HM; Liu, H; Chin, PJ et al. Front Oncol, DOI://10.3389/fonc.2022.812224 (2022)
- The landscape of receptor-mediated precision cancer combination therapy via a single-cell perspective Ahmadi, S; Sukprasert, P; Vegesna, R et al. Nat Commun, DOI://10.1038/s41467-022-29154-2 (2022)
- Complete Genome Sequence of Herpes Simplex Virus 2 Strain G Chang, W; Jiao, X; Sui, H et al. Viruses, DOI://10.3390/v14030536 (2022)
- Single-molecule fluorescence imaging and deep learning reveal highly heterogeneous aggregation of amyloid-β 42 Meng, F; Yoo, J; Chung, HS; , Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2116736119 (2022)
- Assessment of Aortoiliac Atherosclerotic Plaque on CT in Prostate Cancer Patients Undergoing Treatment Lee, S; Elton, DC; Gulley, JL et al. Tomography, DOI://10.3390/tomography8020050 (2022)
- Lamina-specific immunohistochemical signatures in the olfactory bulb of healthy, Alzheimer's and Parkinson's disease patients Murray, HC; Johnson, K; Sedlock, A et al. Commun Biol, DOI://10.1038/s42003-022-03032-5 (2022)
- Pleomorphic xanthoastrocytoma is a heterogeneous entity with pTERT mutations prognosticating shorter survival Ebrahimi, A; Korshunov, A; Reifenberger, G et al. Acta Neuropathol Commun, DOI://10.1186/s40478-021-01308-1 (2022)
- Tuning Formation of Protein-DNA Coacervates by Sequence and Environment Lebold, KM; Best, RB; , J Phys Chem B, DOI://10.1021/acs.jpcb.2c00424 (2022)
- Enhancer-silencer transitions in the human genome Huang, D; Ovcharenko, I; , Genome Res, DOI://10.1101/gr.275992.121 (2022)
- Parallel functional subnetworks embedded in the macaque face patch system Park, SH; Koyano, KW; Russ, BE et al. Sci Adv, DOI://10.1126/sciadv.abm2054 (2022)
- DNA methylation-based prognostic subtypes of chordoma tumors in tissue and plasma Zuccato, JA; Patil, V; Mansouri, S et al. Neuro Oncol, DOI://10.1093/neuonc/noab235 (2022)
- Photoreceptor degeneration in ABCA4-associated retinopathy and its genetic correlates Pfau, M; Cukras, CA; Huryn, LA et al. JCI Insight, DOI://10.1172/jci.insight.155373 (2022)
- Germline SUCLG2 Variants in Patients With Pheochromocytoma and Paraganglioma Hadrava Vanova, K; Pang, Y; Krobova, L et al. J Natl Cancer Inst, DOI://10.1093/jnci/djab158 (2022)
- Preintubation Sequential Organ Failure Assessment Score for Predicting COVID-19 Mortality: External Validation Using Electronic Health Record From 86 U.S. Healthcare Systems to Appraise Current Ventilator Triage Algorithms Keller, MB; Wang, J; Nason, M et al. Crit Care Med, DOI://10.1097/CCM.0000000000005534 (2022)
- A mouse model of occult intestinal colonization demonstrating antibiotic-induced outgrowth of carbapenem-resistant Enterobacteriaceae Sim, CK; Kashaf, SS; Stacy, A et al. Microbiome, DOI://10.1186/s40168-021-01207-6 (2022)
- Clinical Implications of Inter- and Intratumor Heterogeneity of Immune Cell Markers in Lung Cancer Zhao, W; Zhu, B; Hutchinson, A et al. J Natl Cancer Inst, DOI://10.1093/jnci/djab157 (2022)
- Dual-function Spot 42 RNA encodes a 15-amino acid protein that regulates the CRP transcription factor Aoyama, JJ; Raina, M; Zhong, A; Storz, G; , Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2119866119 (2022)
- Severe delayed hypersensitivity reactions to IL-1 and IL-6 inhibitors link to common HLA-DRB1*15 alleles Saper, VE; Ombrello, MJ; Tremoulet, AH et al. Ann Rheum Dis, DOI://10.1136/annrheumdis-2021-220578 (2022)
- Ancestry-Matched and Cross-Ancestry Genetic Risk Scores of Type 2 Diabetes in Pregnant Women and Fetal Growth: A Study in an Ancestrally Diverse Cohort Ouidir, M; Zeng, X; Chatterjee, S et al. Diabetes, DOI://10.2337/db21-0655 (2022)
- Taxonomic distribution and evolutionary analysis of the equol biosynthesis gene cluster Dufault-Thompson, K; Hall, B; Jiang, X; , BMC Genomics, DOI://10.1186/s12864-022-08426-7 (2022)
- A year of COVID-19 GWAS results from the GRASP portal reveals potential genetic risk factors Thibord, F; Chan, MV; Chen, MH; Johnson, AD; , HGG Adv, DOI://10.1016/j.xhgg.2022.100095 (2022)
- Quantification of cerebral blood volume changes caused by visual stimulation at 3 T using DANTE-prepared dual-echo EPI Li, L; Law, C; Marrett, S et al. Magn Reson Med, DOI://10.1002/mrm.29099 (2022)
- Pembrolizumab and decitabine for refractory or relapsed acute myeloid leukemia Goswami, M; Gui, G; Dillon, LW et al. J Immunother Cancer, DOI://10.1136/jitc-2021-003392 (2022)
- Mitochondria in cone photoreceptors act as microlenses to enhance photon delivery and confer directional sensitivity to light Ball, JM; Chen, S; Li, W; , Sci Adv, DOI://10.1126/sciadv.abn2070 (2022)
- Topoisomerase VI is a chirally-selective, preferential DNA decatenase McKie, SJ; Desai, PR; Seol, Y et al. Elife, DOI://10.7554/eLife.67021 (2022)
- Influence of network defects on the conformational structure of nanogel particles: From "closed compact" to "open fractal" nanogel particles Chremos, A; Horkay, F; Douglas, JF; , J Chem Phys, DOI://10.1063/5.0072274 (2022)
- DNA Methylation Profiling: An Emerging Paradigm for Cancer Diagnosis Papanicolau-Sengos, A; Aldape, K; , Annu Rev Pathol, DOI://10.1146/annurev-pathol-042220-022304 (2022)
- A systematic genome-wide account of binding sites for the model transcription factor Gcn4 Coey, CT; Clark, DJ; , Genome Res, DOI://10.1101/gr.276080.121 (2022)
- Bivalent recognition of fatty acyl-CoA by a human integral membrane palmitoyltransferase Lee, CJ; Stix, R; Rana, MS et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2022050119 (2022)
- Interaction of A 3 adenosine receptor ligands with the human multidrug transporter ABCG2 Abel, B; Murakami, M; Tosh, DK et al. Eur J Med Chem, DOI://10.1016/j.ejmech.2022.114103 (2022)
- Japanese pediatric and adult atomic bomb survivor dosimetry: potential improvements using the J45 phantom series and modern Monte Carlo transport Griffin, KT; Sato, T; Funamoto, S et al. Radiat Environ Biophys, DOI://10.1007/s00411-021-00946-2 (2022)
- Activating NTRK2 and ALK receptor tyrosine kinase fusions extend the molecular spectrum of pleomorphic xanthoastrocytomas of early childhood: a diagnostic overlap with infant-type hemispheric glioma Lucas, CG; Abdullaev, Z; Bruggers, CS et al. Acta Neuropathol, DOI://10.1007/s00401-021-02396-y (2022)
- Bridged Piperidine Analogues of a High Affinity Naphthalene-Based P2Y 14 R Antagonist
Wen, Z; Salmaso, V; Jung, YH et al. J Med Chem, DOI://10.1021/acs.jmedchem.1c01964 (2022)
- Immune cell gene expression signatures in diffuse glioma are associated with IDH mutation status, patient outcome and malignant cell state, and highlight the importance of specific cell subsets in glioma biology Mehani, B; Asanigari, S; Chung, HJ et al. Acta Neuropathol Commun, DOI://10.1186/s40478-022-01323-w (2022)
- Evaluating treatment effects in group sequential multivariate longitudinal studies with covariate adjustment Jeffries, NO; Troendle, JF; Geller, NL; , Biometrics, DOI://10.1111/biom.13659 (2022)
- Artificial Intelligence-based Tumor Segmentation in Mouse Models of Lung Adenocarcinoma Arlova, A; Jin, C; Wong-Rolle, A et al. J Pathol Inform, DOI://10.1016/j.jpi.2022.100007 (2022)
- Periconception and Prenatal Exposure to Maternal Perceived Stress and Cord Blood DNA Methylation Polinski, KJ; Putnick, DL; Robinson, SL et al. Epigenet Insights, DOI://10.1177/25168657221082045 (2022)
- DNA methylation cues in nucleosome geometry, stability and unwrapping Li, S; Peng, Y; Landsman, D; Panchenko, AR; , Nucleic Acids Res, DOI://10.1093/nar/gkac097 (2022)
- Immune transcriptome analysis of COVID-19 patients infected with SARS-CoV-2 variants carrying the E484K escape mutation identifies a distinct gene module Lee, HK; Knabl, L; Knabl, L et al. Sci Rep, DOI://10.1038/s41598-022-06752-0 (2022)
- Yap-Sox9 signaling determines hepatocyte plasticity and lineage-specific hepatocarcinogenesis Liu, Y; Zhuo, S; Zhou, Y et al. J Hepatol, DOI://10.1016/j.jhep.2021.11.010 (2022)
- Layer-specific activation in human primary somatosensory cortex during tactile temporal prediction error processing Yu, Y; Huber, L; Yang, J et al. Neuroimage, DOI://10.1016/j.neuroimage.2021.118867 (2022)
- A 3 adenosine receptor agonists containing dopamine moieties for enhanced interspecies affinity Tosh, DK; Salmaso, V; Campbell, RG et al. Eur J Med Chem, DOI://10.1016/j.ejmech.2021.113983 (2022)
- Structure-Activity Relationship of 3-Methylcytidine-5'-α,β-methylenediphosphates as CD73 Inhibitors Scortichini, M; Idris, RM; Moschütz, S et al. J Med Chem, DOI://10.1021/acs.jmedchem.1c01852 (2022)
- MRP5 and MRP9 play a concerted role in male reproduction and mitochondrial function Chambers, IG; Kumar, P; Lichtenberg, J et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2111617119 (2022)
- SARS-CoV-2 infection in free-ranging white-tailed deer Hale, VL; Dennis, PM; McBride, DS et al. Nature, DOI://10.1038/s41586-021-04353-x (2022)
- An open-source tool for automated analysis of breathing behaviors in common marmosets and rodents Bishop, M; Weinhold, M; Turk, AZ et al. Elife, DOI://10.7554/eLife.71647 (2022)
- Epidemiology and genetic diversity of SARS-CoV-2 lineages circulating in Africa Okoh, OS; Nii-Trebi, NI; Jakkari, A et al. iScience, DOI://10.1016/j.isci.2022.103880 (2022)
- Identification of genetic risk loci and prioritization of genes and pathways for myasthenia gravis: a genome-wide association study Chia, R; Saez-Atienzar, S; Murphy, N et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2108672119 (2022)
- The positive-negative mode link between brain connectivity, demographics and behaviour: a pre-registered replication of Smith et al. (2015) Goyal, N; Moraczewski, D; Bandettini, PA et al. R Soc Open Sci, DOI://10.1098/rsos.201090 (2022)
- Multiple in vivo roles for the C-terminal domain of the RNA chaperone Hfq Kavita, K; Zhang, A; Tai, CH et al. Nucleic Acids Res, DOI://10.1093/nar/gkac017 (2022)
- MicroRNA-15a/16-1 Prevents Hepatocellular Carcinoma by Disrupting the Communication Between Kupffer Cells and Regulatory T Cells Liu, N; Chang, CW; Steer, CJ et al. Gastroenterology, DOI://10.1053/j.gastro.2021.10.015 (2022)
- Synthesis, Biological Evaluation, and Molecular Modeling Studies of 3,4-Diarylpyrazoline Series of Compounds as Potent, Nonbrain Penetrant Antagonists of Cannabinoid-1 (CB1R) Receptor with Reduced Lipophilicity Iyer, MR; Cinar, R; Wood, CM et al. J Med Chem, DOI://10.1021/acs.jmedchem.1c01836 (2022)
- MYC amplifies gene expression through global changes in transcription factor dynamics Patange, S; Ball, DA; Wan, Y et al. Cell Rep, DOI://10.1016/j.celrep.2021.110292 (2022)
- Structural insights into the BRAF monomer-to-dimer transition mediated by RAS binding Martinez Fiesco, JA; Durrant, DE; Morrison, DK; Zhang, P; , Nat Commun, DOI://10.1038/s41467-022-28084-3 (2022)
- KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas Rudd, ML; Hansen, NF; Zhang, X et al. PLoS One, DOI://10.1371/journal.pone.0251286 (2022)
- Prenatal origins of suicide mortality: A prospective cohort study in the United States Vidal-Ribas, P; Govender, T; Sundaram, R et al. Transl Psychiatry, DOI://10.1038/s41398-021-01777-x (2022)
- Can AlphaFold2 predict the impact of missense mutations on structure? Buel, GR; Walters, KJ; , Nat Struct Mol Biol, DOI://10.1038/s41594-021-00714-2 (2022)
- Hyperbolic trade-off: The importance of balancing trial and subject sample sizes in neuroimaging Chen, G; Pine, DS; Brotman, MA et al. Neuroimage, DOI://10.1016/j.neuroimage.2021.118786 (2022)
- Autonomic arousals contribute to brain fluid pulsations during sleep Picchioni, D; Özbay, PS; Mandelkow, H et al. Neuroimage, DOI://10.1016/j.neuroimage.2022.118888 (2022)
- Comparison of somatic mutation landscapes in Chinese versus European breast cancer patients Zhu, B; Joo, L; Zhang, T et al. HGG Adv, DOI://10.1016/j.xhgg.2021.100076 (2022)
- Neural network classifiers for images of genetic conditions with cutaneous manifestations Duong, D; Waikel, RL; Hu, P et al. HGG Adv, DOI://10.1016/j.xhgg.2021.100053 (2022)
- Central Vein Sign Profile of Newly Developing Lesions in Multiple Sclerosis: A 3-Year Longitudinal Study Al-Louzi, O; Letchuman, V; Manukyan, S et al. Neurol Neuroimmunol Neuroinflamm, DOI://10.1212/NXI.0000000000001120 (2022)
- Evolution of influenza A virus in intensive and free-range swine farms in Spain Encinas, P; Del Real, G; Dutta, J et al. Virus Evol, DOI://10.1093/ve/veab099 (2022)
- Artificial Intelligence in Medical Imaging and its Impact on the Rare Disease Community: Threats, Challenges and Opportunities Hasani, N; Farhadi, F; Morris, MA et al. PET Clin, DOI://10.1016/j.cpet.2021.09.009 (2022)
- Functional variants in cytochrome b5 type A (CYB5A) are enriched in Southwest American Indian individuals and associate with obesity Day, SE; Traurig, M; Kumar, P et al. Obesity (Silver Spring), DOI://10.1002/oby.23359 (2022)
- Threat imminence reveals links among unfolding of anticipatory physiological response, cortical-subcortical intrinsic functional connectivity, and anxiety Abend, R; Ruiz, SG; Bajaj, MA et al. Neurobiol Stress, DOI://10.1016/j.ynstr.2022.100428 (2022)
- Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern Li, W; Chen, Y; Prévost, J et al. Cell Rep, DOI://10.1016/j.celrep.2021.110210 (2022)
- Dose-dependent relationship between social drinking and brain aging Angebrandt, A; Abulseoud, OA; Kisner, M et al. Neurobiol Aging, DOI://10.1016/j.neurobiolaging.2021.11.008 (2022)
- Integrated analysis of the sialotranscriptome and sialoproteome of the rat flea Xenopsylla cheopis Lu, S; Andersen, JF; Bosio, CF et al. J Proteomics, DOI://10.1016/j.jprot.2021.104476 (2022)
- cLoops2: a full-stack comprehensive analytical tool for chromatin interactions Cao, Y; Liu, S; Ren, G et al. Nucleic Acids Res, DOI://10.1093/nar/gkab1233 (2022)
- Fetal dose from proton pencil beam scanning craniospinal irradiation during pregnancy: a Monte Carlo study Yeom, YS; Griffin, KT; Mille, MM et al. Phys Med Biol, DOI://10.1088/1361-6560/ac4b38 (2022)
- Viscoelastic parameterization of human skin cells characterize material behavior at multiple timescales Parvini, CH; Cartagena-Rivera, AX; Solares, SD; , Commun Biol, DOI://10.1038/s42003-021-02959-5 (2022)
- Bacteroidales species in the human gut are a reservoir of antibiotic resistance genes regulated by invertible promoters Yan, W; Hall, AB; Jiang, X; , NPJ Biofilms Microbiomes, DOI://10.1038/s41522-021-00260-1 (2022)
- Achieving robust somatic mutation detection with deep learning models derived from reference data sets of a cancer sample Sahraeian, SME; Fang, LT; Karagiannis, K et al. Genome Biol, DOI://10.1186/s13059-021-02592-9 (2022)
- Genomic analysis of childhood hearing loss in the Yoruba population of Nigeria Adeyemo, A; Faridi, R; Chattaraj, P et al. Eur J Hum Genet, DOI://10.1038/s41431-021-00984-w (2022)
- Release of linker histone from the nucleosome driven by polyelectrolyte competition with a disordered protein Heidarsson, PO; Mercadante, D; Sottini, A et al. Nat Chem, DOI://10.1038/s41557-021-00839-3 (2022)
- Autocrine vitamin D signaling switches off pro-inflammatory programs of T H 1 cells Chauss, D; Freiwald, T; McGregor, R et al. Nat Immunol, DOI://10.1038/s41590-021-01080-3 (2022)
- Deconvolving clinically relevant cellular immune crosstalk from bulk gene expression using CODEFACS and LIRICS stratifies melanoma patients to anti-PD-1 therapy Wang, K; Patkar, S; Lee, JS et al. Cancer Discov, DOI://10.1158/2159-8290.CD-21-0887 (2022)
- Fluorine-Modifications Contribute to Potent Antiviral Activity against Highly Drug-Resistant HIV-1 and Favorable Blood-Brain Barrier (BBB) Penetration Property of Novel Central Nervous System (CNS)-targeting HIV-1 Protease Inhibitors In Vitro Amano, M; Yedidi, RS; Salcedo-Gómez, PM et al. Antimicrob Agents Chemother, DOI://10.1128/AAC.01715-21 (2022)
- Discovery of novel fish papillomaviruses: From the Antarctic to the commercial fish market Kraberger, S; Austin, C; Farkas, K et al. Virology, DOI://10.1016/j.virol.2021.10.007 (2022)
- Antipsychotic medication-mediated cognitive change in schizophrenia and polygenic score for cognitive ability Blackman, RK; Dickinson, D; Eisenberg, DP et al. Schizophr Res Cogn, DOI://10.1016/j.scog.2021.100223 (2022)
- Artificial Intelligence in Vascular-PET:: Translational and Clinical Applications Paravastu, SS; Theng, EH; Morris, MA et al. PET Clin, DOI://10.1016/j.cpet.2021.09.003 (2022)
2021 (605 papers)
- B cell residency but not T cell-independent IgA switching in the gut requires innate lymphoid cells Zheng, M; Mao, K; Fang, D et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2106754118 (2021)
- Phosphoproteomic Identification of Vasopressin/cAMP/Protein Kinase A-Dependent Signaling in Kidney Salhadar, K; Matthews, A; Raghuram, V et al. Mol Pharmacol, DOI://10.1124/mol.120.119602 (2021)
- The NIH Lipo-COVID Study: A Pilot NMR Investigation of Lipoprotein Subfractions and Other Metabolites in Patients with Severe COVID-19 Ballout, RA; Kong, H; Sampson, M et al. Biomedicines, DOI://10.3390/biomedicines9091090 (2021)
- The SIRPα-CD47 immune checkpoint in NK cells Deuse, T; Hu, X; Agbor-Enoh, S et al. J Exp Med, DOI://10.1084/jem.20200839 (2021)
- Trial and error: A hierarchical modeling approach to test-retest reliability Chen, G; Pine, DS; Brotman, MA et al. Neuroimage, DOI://10.1016/j.neuroimage.2021.118647 (2021)
- Response by Shah et al to Letter Regarding Article, "Cell-Free DNA to Detect Heart Allograft Acute Rejection" Shah, P; Agbor-Enoh, S; Tunc, I et al. Circulation, DOI://10.1161/CIRCULATIONAHA.121.055697 (2021)
- Integration of Single-Cell RNA- and CAGE-seq Reveals Tooth-Enriched Genes Chiba, Y; Yoshizaki, K; Tian, T et al. J Dent Res, DOI://10.1177/00220345211049785 (2021)
- Donor-Derived Cell-Free DNA for Acute Rejection Monitoring in Heart and Lung Transplantation Keller, M; Agbor-Enoh, S; , Curr Transplant Rep, DOI://10.1007/s40472-021-00349-8 (2021)
- Incorporating survival data into case-control studies with incident and prevalent cases Mandal, S; Qin, J; Pfeiffer, RM; , Stat Med, DOI://10.1002/sim.9183 (2021)
- Cancer incidence, patterns, and genotype-phenotype associations in individuals with pathogenic or likely pathogenic germline TP53 variants: an observational cohort study de Andrade, KC; Khincha, PP; Hatton, JN et al. Lancet Oncol, DOI://10.1016/S1470-2045(21)00580-5 (2021)
- Donor derived cell free DNA% is elevated with pathogens that are risk factors for acute and chronic lung allograft injury Bazemore, K; Rohly, M; Permpalung, N et al. J Heart Lung Transplant, DOI://10.1016/j.healun.2021.05.012 (2021)
- Building the mega single-cell transcriptome ocular meta-atlas Swamy, VS; Fufa, TD; Hufnagel, RB; McGaughey, DM; , Gigascience, DOI://10.1093/gigascience/giab061 (2021)
- Mechanistic Insights into Photodynamic Regulation of Adenosine 5'-Triphosphate-Binding Cassette Drug Transporters Liang, BJ; Lusvarghi, S; Ambudkar, SV; Huang, HC; , ACS Pharmacol Transl Sci, DOI://10.1021/acsptsci.1c00138 (2021)
- Role of 53BP1 in end protection and DNA synthesis at DNA breaks Paiano, J; Zolnerowich, N; Wu, W et al. Genes Dev, DOI://10.1101/gad.348667.121 (2021)
- Studying the History of Tumor Evolution from Single-Cell Sequencing Data by Exploring the Space of Binary Matrices Malikić, S; Mehrabadi, FR; Azer, ES et al. J Comput Biol, DOI://10.1089/cmb.2020.0595 (2021)
- Long-Term Report of a Comprehensive Molecular and Genomic Analysis in NRG Oncology/RTOG 0424: A Phase II Study of Radiation and Temozolomide in High-Risk Grade II Glioma Fleming, JL; Pugh, SL; Fisher, BJ et al. JCO Precis Oncol, DOI://10.1200/PO.21.00112 (2021)
- Report of Canonical BCR-ABL1 Fusion in Glioblastoma Pang, Y; Yu, G; Butler, M et al. JCO Precis Oncol, DOI://10.1200/PO.20.00519 (2021)
- Comparison of approaches to transcriptomic analysis in multi-sampled tumors Ku, AT; Wilkinson, S; Sowalsky, AG; , Brief Bioinform, DOI://10.1093/bib/bbab337 (2021)
- Neonatal exposure to a wild-derived microbiome protects mice against diet-induced obesity Hild, B; Dreier, MS; Oh, JH et al. Nat Metab, DOI://10.1038/s42255-021-00439-y (2021)
- Privacy-Preserving Genotype Imputation in a Trusted Execution Environment Dokmai, N; Kockan, C; Zhu, K et al. Res Comput Mol Biol (2021)
- The power of genetic diversity in genome-wide association studies of lipids Graham, SE; Clarke, SL; Wu, KH et al. Nature, DOI://10.1038/s41586-021-04064-3 (2021)
- Clinical and Histopathologic Correlates of Asymmetric Retinitis Pigmentosa Lal, T; Yu, ZX; Guan, B et al. JAMA Ophthalmol, DOI://10.1001/jamaophthalmol.2021.2688 (2021)
- Blood DNA Methylation and Incident Coronary Heart Disease: Evidence From the Strong Heart Study Navas-Acien, A; Domingo-Relloso, A; Subedi, P et al. JAMA Cardiol, DOI://10.1001/jamacardio.2021.2704 (2021)
- A Longitudinal Study of Resting-State Connectivity and Response to Psychostimulant Treatment in ADHD Norman, LJ; Sudre, G; Bouyssi-Kobar, M et al. Am J Psychiatry, DOI://10.1176/appi.ajp.2021.20091342 (2021)
- Cortical and subcortical brain structure in generalized anxiety disorder: findings from 28 research sites in the ENIGMA-Anxiety Working Group Harrewijn, A; Cardinale, EM; Groenewold, NA et al. Transl Psychiatry, DOI://10.1038/s41398-021-01622-1 (2021)
- α-tubulin tail modifications regulate microtubule stability through selective effector recruitment, not changes in intrinsic polymer dynamics Chen, J; Kholina, E; Szyk, A et al. Dev Cell, DOI://10.1016/j.devcel.2021.05.005 (2021)
- Transcriptome of HPβCD-treated Niemann-Pick disease type C1 cells highlights GPNMB as a biomarker for therapeutics Rodriguez-Gil, JL; Baxter, LL; Watkins-Chow, DE et al. Hum Mol Genet, DOI://10.1093/hmg/ddab194 (2021)
- Exploring and Targeting the Tumor Immune Microenvironment of Neuroblastoma Masih, KE; Wei, JS; Milewski, D; Khan, J; , J Cell Immunol, DOI://10.33696/immunology.3.111 (2021)
- BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma Laubscher, D; Gryder, BE; Sunkel, BD et al. Nat Commun, DOI://10.1038/s41467-021-27176-w (2021)
- Androgen receptor and MYC equilibration centralizes on developmental super-enhancer Guo, H; Wu, Y; Nouri, M et al. Nat Commun, DOI://10.1038/s41467-021-27077-y (2021)
- Use of donor-derived-cell-free DNA as a marker of early allograft injury in primary graft dysfunction (PGD) to predict the risk of chronic lung allograft dysfunction (CLAD) Keller, M; Bush, E; Diamond, JM et al. J Heart Lung Transplant, DOI://10.1016/j.healun.2021.02.008 (2021)
- Serum fructosamine and glycemic status in the presence of the sickle cell mutation Doumatey, AP; Feron, H; Ekoru, K et al. Diabetes Res Clin Pract, DOI://10.1016/j.diabres.2021.108918 (2021)
- Sex Chromosome Dosage Effects on White Matter Structure in the Human Brain Warling, A; Yavi, M; Clasen, LS et al. Cereb Cortex, DOI://10.1093/cercor/bhab162 (2021)
- Fasting blood glucose as a predictor of mortality: Lost in translation Palliyaguru, DL; Shiroma, EJ; Nam, JK et al. Cell Metab, DOI://10.1016/j.cmet.2021.08.013 (2021)
- Structure activity relationship of 3-nitro-2-(trifluoromethyl)-2H-chromene derivatives as P2Y 6 receptor antagonists Jung, YH; Jain, S; Gopinatth, V et al. Bioorg Med Chem Lett, DOI://10.1016/j.bmcl.2021.128008 (2021)
- Connectome 2.0: Developing the next-generation ultra-high gradient strength human MRI scanner for bridging studies of the micro-, meso- and macro-connectome Huang, SY; Witzel, T; Keil, B et al. Neuroimage, DOI://10.1016/j.neuroimage.2021.118530 (2021)
- Myeloid-Derived Suppressive Cell Expansion Promotes Melanoma Growth and Autoimmunity by Inhibiting CD40/IL27 Regulation in Macrophages Valencia, JC; Erwin-Cohen, RA; Clavijo, PE et al. Cancer Res, DOI://10.1158/0008-5472.CAN-21-1148 (2021)
- Lysine Demethylase 5A is Required for MYC Driven Transcription in Multiple Myeloma Ohguchi, H; Park, PMC; Wang, T et al. Blood Cancer Discov, DOI://10.1158/2643-3230.BCD-20-0108 (2021)
- Auditory and olfactory findings in patients with USH2A-related retinal degeneration-Findings at baseline from the rate of progression in USH2A-related retinal degeneration natural history study (RUSH2A) Iannaccone, A; Brewer, CC; Cheng, P et al. Am J Med Genet A, DOI://10.1002/ajmg.a.62437 (2021)
- Clinical diagnosis of presumed SOX2 gonadosomatic mosaicism Daich Varela, M; Hufnagel, RB; Guan, B et al. Ophthalmic Genet, DOI://10.1080/13816810.2021.1888127 (2021)
- Impact of Prior Treatment on the Efficacy of Adoptive Transfer of Tumor-Infiltrating Lymphocytes in Patients with Metastatic Melanoma Seitter, SJ; Sherry, RM; Yang, JC et al. Clin Cancer Res, DOI://10.1158/1078-0432.CCR-21-1171 (2021)
- Age-related DNA methylation in paired normal and tumour breast tissue in Chinese breast cancer patients Kiely, M; Tse, LA; Koka, H et al. Epigenetics, DOI://10.1080/15592294.2020.1819661 (2021)
- A custom capture sequence approach for oculocutaneous albinism identifies structural variant alleles at the OCA2 locus Loftus, SK; Lundh, L; Watkins-Chow, DE et al. Hum Mutat, DOI://10.1002/humu.24257 (2021)
- Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development Bresciani, E; Carrington, B; Yu, K et al. Blood Adv, DOI://10.1182/bloodadvances.2020003969 (2021)
- Oncostatin M can sensitize sensory neurons in inflammatory pruritus Tseng, PY; Hoon, MA; , Sci Transl Med, DOI://10.1126/scitranslmed.abe3037 (2021)
- Genetic effects on liver chromatin accessibility identify disease regulatory variants Currin, KW; Erdos, MR; Narisu, N et al. Am J Hum Genet, DOI://10.1016/j.ajhg.2021.05.001 (2021)
- Curvature Energetics Determined by Alchemical Simulation on Four Topologically Distinct Lipid Phases Beaven, AH; Arnarez, C; Lyman, E et al. J Phys Chem B, DOI://10.1021/acs.jpcb.0c09458 (2021)
- A semiparametric kernel independence test with application to mutational signatures Lee, D; Zhu, B; , J Am Stat Assoc, DOI://10.1080/01621459.2020.1871357 (2021)
- Atoh7-independent specification of retinal ganglion cell identity Brodie-Kommit, J; Clark, BS; Shi, Q et al. Sci Adv, DOI://10.1126/sciadv.abe4983 (2021)
- Cellular abundance shapes function in piRNA-guided genome defense Genzor, P; Konstantinidou, P; Stoyko, D et al. Genome Res, DOI://10.1101/gr.275478.121 (2021)
- Mechanistic gene networks inferred from single-cell data with an outlier-insensitive method Han, J; Perera, S; Wunderlich, Z; Periwal, V; , Math Biosci, DOI://10.1016/j.mbs.2021.108722 (2021)
- How asymmetric DNA replication achieves symmetrical fidelity Zhou, ZX; Lujan, SA; Burkholder, AB et al. Nat Struct Mol Biol, DOI://10.1038/s41594-021-00691-6 (2021)
- Fasting-induced FOXO4 blunts human CD4+ T helper cell responsiveness Han, K; Singh, K; Rodman, MJ et al. Nat Metab, DOI://10.1038/s42255-021-00356-0 (2021)
- The role of Niemann-Pick type C2 in zebrafish embryonic development Tseng, WC; Johnson Escauriza, AJ; Tsai-Morris, CH et al. Development, DOI://10.1242/dev.194258 (2021)
- Genome editing in human hematopoietic stem and progenitor cells via CRISPR-Cas9-mediated homology-independent targeted integration Bloomer, H; Smith, RH; Hakami, W; Larochelle, A; , Mol Ther, DOI://10.1016/j.ymthe.2020.12.010 (2021)
- Metastatic Castration-Resistant Prostate Cancer Remains Dependent on Oncogenic Drivers Found in Primary Tumors Einstein, DJ; Arai, S; Calagua, C et al. JCO Precis Oncol, DOI://10.1200/PO.21.00059 (2021)
- The Haskins pediatric atlas: a magnetic-resonance-imaging-based pediatric template and atlas Molfese, PJ; Glen, D; Mesite, L et al. Pediatr Radiol, DOI://10.1007/s00247-020-04875-y (2021)
- Targeted Single-Cell RNA-seq Identifies Minority Cell Types of Kidney Distal Nephron Chen, L; Chou, CL; Knepper, MA; , J Am Soc Nephrol, DOI://10.1681/ASN.2020101407 (2021)
- The RUNX1 database (RUNX1db): establishment of an expert curated RUNX1 registry and genomics database as a public resource for familial platelet disorder with myeloid malignancy Homan, CC; King-Smith, SL; Lawrence, DM et al. Haematologica, DOI://10.3324/haematol.2021.278762 (2021)
- Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis Johnson, JO; Chia, R; Miller, DE et al. JAMA Neurol, DOI://10.1001/jamaneurol.2021.2598 (2021)
- Using a Recently Approved Tumor Mutational Burden Biomarker to Stratify Patients for Immunotherapy May Introduce a Sex Bias Sinha, N; Sinha, S; Cheng, K et al. JCO Precis Oncol, DOI://10.1200/PO.21.00168 (2021)
- Parsing Immune Correlates of Protection Against SARS-CoV-2 from Biomedical Literature Foote, SL; Jones, S; Lockmuller, J et al. AMIA Annu Symp Proc, 1942-597X (2021)
- Cell-Free DNA to Detect Heart Allograft Acute Rejection Agbor-Enoh, S; Shah, P; Tunc, I et al. Circulation, DOI://10.1161/CIRCULATIONAHA.120.049098 (2021)
- Meta-analysis of epigenome-wide association studies of carotid intima-media thickness Portilla-Fernández, E; Hwang, SJ; Wilson, R et al. Eur J Epidemiol, DOI://10.1007/s10654-021-00759-z (2021)
- Alterations of human skin microbiome and expansion of antimicrobial resistance after systemic antibiotics Jo, JH; Harkins, CP; Schwardt, NH et al. Sci Transl Med, DOI://10.1126/scitranslmed.abd8077 (2021)
- Meta-analyses identify DNA methylation associated with kidney function and damage Schlosser, P; Tin, A; Matias-Garcia, PR et al. Nat Commun, DOI://10.1038/s41467-021-27234-3 (2021)
- Proteomic Biomarker Analysis of Serum from Japanese Field Mice (Apodemus Speciosus) Collected within the Fukushima Difficult-to-return Zone Sproull, M; Hayes, J; Ishiniwa, H et al. Health Phys, DOI://10.1097/HP.0000000000001467 (2021)
- Tentorial venous anatomy of mice and humans Lookian, PP; Chandrashekhar, V; Cappadona, A et al. JCI Insight, DOI://10.1172/jci.insight.151222 (2021)
- Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus Tin, A; Schlosser, P; Matias-Garcia, PR et al. Nat Commun, DOI://10.1038/s41467-021-27198-4 (2021)
- Helminth-Induced Human Gastrointestinal Dysbiosis: a Systematic Review and Meta-Analysis Reveals Insights into Altered Taxon Diversity and Microbial Gradient Collapse Kupritz, J; Angelova, A; Nutman, TB; Gazzinelli-Guimaraes, PH; , mBio, DOI://10.1128/mBio.02890-21 (2021)
- A UVB-responsive common variant at chromosome band 7p21.1 confers tanning response and melanoma risk via regulation of the aryl hydrocarbon receptor, AHR Xu, M; Mehl, L; Zhang, T et al. Am J Hum Genet, DOI://10.1016/j.ajhg.2021.07.002 (2021)
- Cell-type-specific meQTLs extend melanoma GWAS annotation beyond eQTLs and inform melanocyte gene-regulatory mechanisms Zhang, T; Choi, J; Dilshat, R et al. Am J Hum Genet, DOI://10.1016/j.ajhg.2021.06.018 (2021)
- The nuclear transcription factor, TAF7, is a cytoplasmic regulator of protein synthesis Cheng, D; Semmens, K; McManus, E et al. Sci Adv, DOI://10.1126/sciadv.abi5751 (2021)
- Cryo-EM structure of the autoinhibited state of myosin-2 Heissler, SM; Arora, AS; Billington, N et al. Sci Adv, DOI://10.1126/sciadv.abk3273 (2021)
- 25-Hydroxycholesterol Inhibits Kaposi's Sarcoma Herpesvirus and Epstein-Barr Virus Infections and Activates Inflammatory Cytokine Responses Serquiña, AKP; Tagawa, T; Oh, D et al. mBio, DOI://10.1128/mBio.02907-21 (2021)
- A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes Calagua, C; Ficial, M; Jansen, CS et al. Clin Cancer Res, DOI://10.1158/1078-0432.CCR-21-0121 (2021)
- Genetic Overlap Profiles of Cognitive Ability in Psychotic and Affective Illnesses: A Multisite Study of Multiplex Pedigrees Knowles, EEM; Peralta, JM; Almasy, L et al. Biol Psychiatry, DOI://10.1016/j.biopsych.2021.03.012 (2021)
- Retroviral integrase: Structure, mechanism, and inhibition Passos, DO; Li, M; Craigie, R; Lyumkis, D; , Enzymes, DOI://10.1016/bs.enz.2021.06.007 (2021)
- The Vaginal Microbiome of Nonhuman Primates Can Be Only Transiently Altered to Become Lactobacillus Dominant without Reducing Inflammation Langner, CA; Ortiz, AM; Flynn, JK et al. Microbiol Spectr, DOI://10.1128/Spectrum.01074-21 (2021)
- Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors Sievers, P; Henneken, SC; Blume, C et al. Acta Neuropathol, DOI://10.1007/s00401-021-02356-6 (2021)
- High-resolution mapping and digital atlas of subcortical regions in the macaque monkey based on matched MAP-MRI and histology Saleem, KS; Avram, AV; Glen, D et al. Neuroimage, DOI://10.1016/j.neuroimage.2021.118759 (2021)
- Tissue Trafficking Kinetics of Rhesus Macaque Natural Killer Cells Measured by Serial Intravascular Staining Mortlock, RD; Wu, C; Potter, EL et al. Front Immunol, DOI://10.3389/fimmu.2021.772332 (2021)
- PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory Cannons, JL; Villarino, AV; Kapnick, SM et al. Cell Rep, DOI://10.1016/j.celrep.2021.109804 (2021)
- Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1 Sievers, P; Sill, M; Blume, C et al. Acta Neuropathol, DOI://10.1007/s00401-020-02247-2 (2021)
- The Spectrum of the Deficiency of Adenosine Deaminase 2: An Observational Analysis of a 60 Patient Cohort Barron, KS; Aksentijevich, I; Deuitch, NT et al. Front Immunol, DOI://10.3389/fimmu.2021.811473 (2021)
- New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1 Zong, G; Jork, N; Hostachy, S et al. FASEB J, DOI://10.1096/fj.202001489R (2021)
- Converging Multi-modal Evidence for Implicit Threat-Related Bias in Pediatric Anxiety Disorders Abend, R; Bajaj, MA; Matsumoto, C et al. Res Child Adolesc Psychopathol, DOI://10.1007/s10802-020-00712-w (2021)
- GLYCO: a tool to quantify glycan shielding of glycosylated proteins Lee, M; Reveiz, M; Rawi, R et al. Bioinformatics, DOI://10.1093/bioinformatics/btab791 (2021)
- Cell-free DNA beyond a biomarker for rejection: Biological trigger of tissue injury and potential therapeutics Tsuji, N; Agbor-Enoh, S; , J Heart Lung Transplant, DOI://10.1016/j.healun.2021.03.007 (2021)
- Argos: A toolkit for tracking multiple animals in complex visual environments Ray S; Stopfer MA Methods Ecol. Evol. , /10.1111/2041-210X.13776 (2021)
- Use of photoimmunoconjugates to characterize ABCB1 in cancer cells Liang, BJ; Lusvarghi, S; Ambudkar, SV; Huang, HC; , Nanophotonics, DOI://10.1515/nanoph-2021-0252 (2021)
- Temperature Dependence of Hydrophobic and Hydrophilic Forces and Interactions Durell, SR; Ben-Naim, A; , J Phys Chem B, DOI://10.1021/acs.jpcb.1c07802 (2021)
- An Integrative Sialomic Analysis Reveals Molecules From Triatoma sordida (Hemiptera: Reduviidae) Praça, YR; Santiago, PB; Charneau, S et al. Front Cell Infect Microbiol, DOI://10.3389/fcimb.2021.798924 (2021)
- Correction: Regulatory roles of Escherichia coli 5' UTR and ORF-internal RNAs detected by 3' end mapping Storz, G; Adams, PP; Baniulyte, G et al. Elife, DOI://10.7554/eLife.69260 (2021)
- Detection of metabolic change in glioblastoma cells after radiotherapy using hyperpolarized 13 C-MRI Kawai, T; Brender, JR; Lee, JA et al. NMR Biomed, DOI://10.1002/nbm.4514 (2021)
- RNA Externalized by Neutrophil Extracellular Traps Promotes Inflammatory Pathways in Endothelial Cells Blanco, LP; Wang, X; Carlucci, PM et al. Arthritis Rheumatol, DOI://10.1002/art.41796 (2021)
- Efficient Immune Cell Genome Engineering with Enhanced CRISPR Editing Tools Chan, W; Gottschalk, RA; Yao, Y et al. Immunohorizons, DOI://10.4049/immunohorizons.2000082 (2021)
- Reversion mutations in phosphoprotein P of a codon-pair-deoptimized human respiratory syncytial virus confer increased transcription, immunogenicity, and genetic stability without loss of attenuation Chen, JW; Yang, L; Santos, C et al. PLoS Pathog, DOI://10.1371/journal.ppat.1010191 (2021)
- A sequence-based method for predicting extant fold switchers that undergo α-helix ↔ β-strand transitions Mishra, S; Looger, LL; Porter, LL; , Biopolymers, DOI://10.1002/bip.23471 (2021)
- Identification of neoantigen-reactive T lymphocytes in the peripheral blood of a patient with glioblastoma Leko, V; Cafri, G; Yossef, R et al. J Immunother Cancer, DOI://10.1136/jitc-2021-002882 (2021)
- The mechanism of Raf activation through dimerization Zhang, M; Maloney, R; Jang, H; Nussinov, R; , Chem Sci, DOI://10.1039/d1sc03444h (2021)
- Genomic and Transcriptomic Analysis of Relapsed and Refractory Childhood Solid Tumors Reveals a Diverse Molecular Landscape and Mechanisms of Immune Evasion Byron, SA; Hendricks, WPD; Nagulapally, AB et al. Cancer Res, DOI://10.1158/0008-5472.CAN-21-1033 (2021)
- TNF plays a crucial role in inflammation by signaling via T cell TNFR2 Alam, MS; Otsuka, S; Wong, N et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2109972118 (2021)
- Inhibition of cytoplasmic EZH2 induces antitumor activity through stabilization of the DLC1 tumor suppressor protein Tripathi, BK; Anderman, MF; Bhargava, D et al. Nat Commun, DOI://10.1038/s41467-021-26993-3 (2021)
- Dynamic bulge nucleotides in the KSHV PAN ENE triple helix provide a unique binding platform for small molecule ligands Swain, M; Ageeli, AA; Kasprzak, WK et al. Nucleic Acids Res, DOI://10.1093/nar/gkab1170 (2021)
- Comprehensive multiomic characterization of human papillomavirus-driven recurrent respiratory papillomatosis reveals distinct molecular subtypes Sievers, C; Robbins, Y; Bai, K et al. Commun Biol, DOI://10.1038/s42003-021-02942-0 (2021)
- Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma Lu, X; Sabbasani, VR; Osei-Amponsa, V et al. Nat Commun, DOI://10.1038/s41467-021-27570-4 (2021)
- Nuclear pore protein NUP210 depletion suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response Amin, R; Shukla, A; Zhu, JJ et al. Nat Commun, DOI://10.1038/s41467-021-27451-w (2021)
- A novel lineage of polyomaviruses identified in bark scorpions Schmidlin, K; Kraberger, S; Cook, C et al. Virology, DOI://10.1016/j.virol.2021.08.008 (2021)
- Variational embedding of protein folding simulations using Gaussian mixture variational autoencoders Ghorbani, M; Prasad, S; Klauda, JB; Brooks, BR; , J Chem Phys, DOI://10.1063/5.0069708 (2021)
- Integrated Molecular-Morphologic Meningioma Classification: A Multicenter Retrospective Analysis, Retrospectively and Prospectively Validated Maas, SLN; Stichel, D; Hielscher, T et al. J Clin Oncol, DOI://10.1200/JCO.21.00784 (2021)
- Interrogation of clonal tracking data using barcodetrackR Espinoza DA; Mortlock RD; et al Nat. Comp. Sci., doi://10.1038/s43588-021-00057-4 (2021)
- Identification of Genetic Risk Factors for Familial Urinary Bladder Cancer: An Exome Sequencing Study Pemov, A; Wegman-Ostrosky, T; Kim, J et al. JCO Precis Oncol, DOI://10.1200/PO.21.00115 (2021)
- Endogenous Retroviral Elements in Human Development and Central Nervous System Embryonal Tumors Doucet-O'Hare, TT; Rosenblum, JS; Shah, AH et al. J Pers Med, DOI://10.3390/jpm11121332 (2021)
- Luminal microvesicles uniquely influence translocating bacteria after SIV infection Flynn, JK; Langner, CA; Karmele, EP et al. Mucosal Immunol, DOI://10.1038/s41385-021-00393-8 (2021)
- Outlier detection in multimodal MRI identifies rare individual phenotypes among more than 15,000 brains Ma, Z; Reich, DS; Dembling, S et al. Hum Brain Mapp, DOI://10.1002/hbm.25756 (2021)
- Genotype-cancer association in patients with Fanconi anemia due to pathogenic variants in FANCD1 (BRCA2) or FANCN (PALB2) McReynolds, LJ; Biswas, K; Giri, N et al. Cancer Genet, DOI://10.1016/j.cancergen.2021.10.001 (2021)
- RAS induced senescence of skin keratinocytes is mediated through Rho-associated protein kinase (ROCK) Lee, AJ; Fraser, E; Flowers, B et al. Mol Carcinog, DOI://10.1002/mc.23351 (2021)
- Molecular studies into cell biological role of Copine-4 in Retinal Ganglion Cells Goel, M; Aponte, AM; Wistow, G; Badea, TC; , PLoS One, DOI://10.1371/journal.pone.0255860 (2021)
- Temporal inhibition of chromatin looping and enhancer accessibility during neuronal remodeling Chen, D; McManus, CE; Radmanesh, B et al. Nat Commun, DOI://10.1038/s41467-021-26628-7 (2021)
- Screening by deep sequencing reveals mediators of microRNA tailing in C. elegans Vieux, KF; Prothro, KP; Kelley, LH et al. Nucleic Acids Res, DOI://10.1093/nar/gkab840 (2021)
- A machine learning model for ranking candidate HLA class I neoantigens based on known neoepitopes from multiple human tumor types Gartner, JJ; Parkhurst, MR; Gros, A et al. Nat Cancer, DOI://10.1038/s43018-021-00197-6 (2021)
- Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U Frazier, MN; Dillard, LB; Krahn, JM et al. Nucleic Acids Res, DOI://10.1093/nar/gkab719 (2021)
- gcMECM: graph clustering of mutual exclusivity of cancer mutations Hu, Y; Yan, C; Chen, Q; Meerzaman, D; , BMC Bioinformatics, DOI://10.1186/s12859-021-04505-w (2021)
- Large parental differences in chromatin organization in pancreatic beta cell line explaining diabetes susceptibility effects Jian, X; Felsenfeld, G; , Nat Commun, DOI://10.1038/s41467-021-24635-2 (2021)
- Tumor heterogeneity assessed by sequencing and fluorescence in situ hybridization (FISH) data Lei, H; Gertz, EM; Schäffer, AA et al. Bioinformatics, DOI://10.1093/bioinformatics/btab504 (2021)
- A Transcription Start Site Map in Human Pancreatic Islets Reveals Functional Regulatory Signatures Varshney, A; Kyono, Y; Elangovan, VR et al. Diabetes, DOI://10.2337/db20-1087 (2021)
- Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver Flynn, BP; Birnie, MT; Kershaw, YM et al. PLoS Genet, DOI://10.1371/journal.pgen.1009737 (2021)
- The dynamic nature of the K-Ras/calmodulin complex can be altered by oncogenic mutations Abdelkarim, H; Leschinsky, N; Jang, H et al. Curr Opin Struct Biol, DOI://10.1016/j.sbi.2021.06.008 (2021)
- Lentzeacins A-E, New Bacterial-Derived 2,5- and 2,6-Disubstituted Pyrazines from a BGC-Rich Soil Bacterium Lentzea sp. GA3-008 Liu, HB; Davison, JR; Rajwani, R et al. Molecules, DOI://10.3390/molecules26237197 (2021)
- Tumor Mutation Burden, Expressed Neoantigens and the Immune Microenvironment in Diffuse Gliomas Yu, G; Pang, Y; Merchant, M et al. Cancers (Basel), DOI://10.3390/cancers13236092 (2021)
- The Hydrogen-Coupled Oligopeptide Membrane Cotransporter Pept2 is SUMOylated in Kidney Distal Convoluted Tubule Cells Aroankins, TS; Murali, SK; Fenton, RA; Wu, Q; , Front Mol Biosci, DOI://10.3389/fmolb.2021.790606 (2021)
- Immuno-transcriptomic profiling of extracranial pediatric solid malignancies Brohl, AS; Sindiri, S; Wei, JS et al. Cell Rep, DOI://10.1016/j.celrep.2021.110047 (2021)
- Inferred expression regulator activities suggest genes mediating cardiometabolic genetic signals Hoskins, JW; Chung, CC; O'Brien, A et al. PLoS Comput Biol, DOI://10.1371/journal.pcbi.1009563 (2021)
- Single-nucleus transcriptomic analysis of human dorsal root ganglion neurons Nguyen, MQ; von Buchholtz, LJ; Reker, AN et al. Elife, DOI://10.7554/eLife.71752 (2021)
- CD63 + and MHC Class I + Subsets of Extracellular Vesicles Produced by Wild-Type and CD47-Deficient Jurkat T Cells Have Divergent Functional Effects on Endothelial Cell Gene Expression Kaur, S; Elkahloun, AG; Petersen, JD et al. Biomedicines, DOI://10.3390/biomedicines9111705 (2021)
- Multiview confocal super-resolution microscopy Wu, Y; Han, X; Su, Y et al. Nature, DOI://10.1038/s41586-021-04110-0 (2021)
- Genome-Guided Discovery of Natural Products through Multiplexed Low-Coverage Whole-Genome Sequencing of Soil Actinomycetes on Oxford Nanopore Flongle Rajwani, R; Ohlemacher, SI; Zhao, G et al. mSystems, DOI://10.1128/mSystems.01020-21 (2021)
- Cataloging Human PRDM9 Allelic Variation Using Long-Read Sequencing Reveals PRDM9 Population Specificity and Two Distinct Groupings of Related Alleles Alleva, B; Brick, K; Pratto, F et al. Front Cell Dev Biol, DOI://10.3389/fcell.2021.675286 (2021)
- Bayesian identification of candidate transcription factors for the regulation of Aqp2 gene expression Kikuchi, H; Jung, HJ; Raghuram, V et al. Am J Physiol Renal Physiol, DOI://10.1152/ajprenal.00204.2021 (2021)
- Integration of adeno-associated virus (AAV) into the genomes of most Thai and Mongolian liver cancer patients does not induce oncogenesis Schäffer, AA; Dominguez, DA; Chapman, LM et al. BMC Genomics, DOI://10.1186/s12864-021-08098-9 (2021)
- Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfaces Lee, M; Changela, A; Gorman, J et al. Nat Commun, DOI://10.1038/s41467-021-26579-z (2021)
- Whole genome and exome sequencing reference datasets from a multi-center and cross-platform benchmark study Zhao, Y; Fang, LT; Shen, TW et al. Sci Data, DOI://10.1038/s41597-021-01077-5 (2021)
- Overcoming Acquired Epigenetic Resistance to BTK Inhibitors Shaffer, AL; Phelan, JD; Wang, JQ et al. Blood Cancer Discov, DOI://10.1158/2643-3230.BCD-21-0063 (2021)
- CSC software corrects off-target mediated gRNA depletion in CRISPR-Cas9 essentiality screens Perez, AR; Sala, L; Perez, RK; Vidigal, JA; , Nat Commun, DOI://10.1038/s41467-021-26722-w (2021)
- A large Canadian cohort provides insights into the genetic architecture of human hair colour Lona-Durazo, F; Mendes, M; Thakur, R et al. Commun Biol, DOI://10.1038/s42003-021-02764-0 (2021)
- Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction Ahmad, J; Jiang, J; Boyd, LF et al. J Biol Chem, DOI://10.1016/j.jbc.2021.101202 (2021)
- Genome-scale metabolic modeling reveals SARS-CoV-2-induced metabolic changes and antiviral targets Cheng, K; Martin-Sancho, L; Pal, LR et al. Mol Syst Biol, DOI://10.15252/msb.202110260 (2021)
- PERK signaling through C/EBPδ contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cells Sheshadri, N; Poria, DK; Sharan, S et al. Cell Death Dis, DOI://10.1038/s41419-021-04318-y (2021)
- Placental Gene Co-expression Network for Maternal Plasma Lipids Revealed Enrichment of Inflammatory Response Pathways Ouidir, M; Chatterjee, S; Mendola, P et al. Front Genet, DOI://10.3389/fgene.2021.681095 (2021)
- Methylphenidate modulates interactions of anxiety with cognition Gaillard, C; Lago, TR; Gorka, AX et al. Transl Psychiatry, DOI://10.1038/s41398-021-01621-2 (2021)
- FGFR1-TACC1 fusion associated with malignant transformation in a primary spinal cord glioma: a case report Asuzu, DT; Desai, B; Maggio, D et al. J Spine Surg, DOI://10.21037/jss-21-24 (2021)
- DNA methylation profiling as a model for discovery and precision diagnostics in neuro-oncology Pratt, D; Sahm, F; Aldape, K; , Neuro Oncol, DOI://10.1093/neuonc/noab143 (2021)
- A 584 bp deletion in CTRB2 inhibits chymotrypsin B2 activity and secretion and confers risk of pancreatic cancer Jermusyk, A; Zhong, J; Connelly, KE et al. Am J Hum Genet, DOI://10.1016/j.ajhg.2021.09.002 (2021)
- Development of CHARMM Additive Potential Energy Parameters for α-Methyl Amino Acids Pane, AJ; Yu, W; Aytenfisu, A et al. J Phys Chem B, DOI://10.1021/acs.jpcb.1c07202 (2021)
- Identification of BvgA-Dependent and BvgA-Independent Small RNAs (sRNAs) in Bordetella pertussis Using the Prokaryotic sRNA Prediction Toolkit ANNOgesic Moon, K; Sim, M; Tai, CH et al. Microbiol Spectr, DOI://10.1128/Spectrum.00044-21 (2021)
- Cigarette Smoking and Opium Use in Relation to the Oral Microbiota in Iran Wu, Z; Han, Y; Caporaso, JG et al. Microbiol Spectr, DOI://10.1128/Spectrum.00138-21 (2021)
- T Cell-Mediated Antitumor Immunity Cooperatively Induced By TGFβR1 Antagonism and Gemcitabine Counteracts Reformation of the Stromal Barrier in Pancreatic Cancer Li, D; Schaub, N; Guerin, TM et al. Mol Cancer Ther, DOI://10.1158/1535-7163.MCT-20-0620 (2021)
- A disease-specific language representation model for cerebrovascular disease research Lin, CH; Hsu, KC; Liang, CK et al. Comput Methods Programs Biomed, DOI://10.1016/j.cmpb.2021.106446 (2021)
- Pupal behavior emerges from unstructured muscle activity in response to neuromodulation in Drosophila Elliott, AD; Berndt, A; Houpert, M et al. Elife, DOI://10.7554/eLife.68656 (2021)
- A chemical probe based on the PreQ 1 metabolite enables transcriptome-wide mapping of binding sites Balaratnam, S; Rhodes, C; Bume, DD et al. Nat Commun, DOI://10.1038/s41467-021-25973-x (2021)
- Tyrp1 Mutant Variants Associated with OCA3: Computational Characterization of Protein Stability and Ligand Binding Patel, MH; Dolinska, MB; Sergeev, YV; , Int J Mol Sci, DOI://10.3390/ijms221910203 (2021)
- Repeated strand invasion and extensive branch migration are hallmarks of meiotic recombination Ahuja, JS; Harvey, CS; Wheeler, DL; Lichten, M; , Mol Cell, DOI://10.1016/j.molcel.2021.08.003 (2021)
- Sp6/Epiprofin is a master regulator in the developing tooth Rhodes, CS; Yoshitomi, Y; Burbelo, PD et al. Biochem Biophys Res Commun, DOI://10.1016/j.bbrc.2021.10.017 (2021)
- Deep Learning CT-based Quantitative Visualization Tool for Liver Volume Estimation: Defining Normal and Hepatomegaly Perez, AA; Noe-Kim, V; Lubner, MG et al. Radiology, DOI://10.1148/radiol.2021210531 (2021)
- Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis Suwala, AK; Stichel, D; Schrimpf, D et al. Acta Neuropathol, DOI://10.1007/s00401-020-02243-6 (2021)
- Genomic and evolutionary classification of lung cancer in never smokers Zhang, T; Joubert, P; Ansari-Pour, N et al. Nat Genet, DOI://10.1038/s41588-021-00920-0 (2021)
- Prioritizing and characterizing functionally relevant genes across human tissues Somepalli, G; Sahoo, S; Singh, A; Hannenhalli, S; , PLoS Comput Biol, DOI://10.1371/journal.pcbi.1009194 (2021)
- Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing Fang, LT; Zhu, B; Zhao, Y et al. Nat Biotechnol, DOI://10.1038/s41587-021-00993-6 (2021)
- Rigorous treatment of pairwise and many-body electrostatic interactions among dielectric spheres at the Debye-Hückel level Obolensky, OI; Doerr, TP; Yu, YK; , Eur Phys J E Soft Matter, DOI://10.1140/epje/s10189-021-00131-9 (2021)
- Ecdysoneless protein regulates viral and cellular mRNA splicing to promote cervical oncogenesis Mirza, S; Kalluchi, A; Raza, M et al. Mol Cancer Res, DOI://10.1158/1541-7786.MCR-21-0567 (2021)
- A novel exome probe set captures phototransduction genes across birds (Aves) enabling efficient analysis of vision evolution White, ND; Batz, ZA; Braun, EL et al. Mol Ecol Resour, DOI://10.1111/1755-0998.13496 (2021)
- Adintoviruses: a proposed animal-tropic family of midsize eukaryotic linear dsDNA (MELD) viruses Starrett, GJ; Tisza, MJ; Welch, NL et al. Virus Evol, DOI://10.1093/ve/veaa055 (2021)
- A mixed-model approach for powerful testing of genetic associations with cancer risk incorporating tumor characteristics Zhang, H; Zhao, N; Ahearn, TU et al. Biostatistics, DOI://10.1093/biostatistics/kxz065 (2021)
- Neanderthal-derived genetic variation in living humans relates to schizophrenia diagnosis, to psychotic symptom severity, and to dopamine synthesis Gregory, MD; Eisenberg, DP; Hamborg, M et al. Am J Med Genet B Neuropsychiatr Genet, DOI://10.1002/ajmg.b.32872 (2021)
- Social groups constrain the spatiotemporal dynamics of wild sifaka gut microbiomes Perofsky, AC; Ancel Meyers, L; Abondano, LA et al. Mol Ecol, DOI://10.1111/mec.16193 (2021)
- Corrections in the CHARMM36 Parametrization of Chloride Interactions with Proteins, Lipids, and Alkali Cations, and Extension to Other Halide Anions Orabi, EA; Öztürk, TN; Bernhardt, N; Faraldo-Gómez, JD; , J Chem Theory Comput, DOI://10.1021/acs.jctc.1c00550 (2021)
- NMDARs Drive the Expression of Neuropsychiatric Disorder Risk Genes Within GABAergic Interneuron Subtypes in the Juvenile Brain Mahadevan, V; Mitra, A; Zhang, Y et al. Front Mol Neurosci, DOI://10.3389/fnmol.2021.712609 (2021)
- Identification of DNA Methylation Changes That Predict Onset of Post-traumatic Stress Disorder and Depression Following Physical Trauma Martin, CA; Vorn, R; Schrieber, M et al. Front Neurosci, DOI://10.3389/fnins.2021.738347 (2021)
- Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques Bochart, RM; Busman-Sahay, K; Bondoc, S et al. PLoS Pathog, DOI://10.1371/journal.ppat.1009565 (2021)
- Deconstructing the Treatment Effect of Remdesivir in the Adaptive COVID-19 Treatment Trial-1: Implications for Critical Care Resource Utilization Fintzi, J; Bonnett, T; Sweeney, DA et al. Clin Infect Dis, DOI://10.1093/cid/ciab712 (2021)
- Microbial signatures in the lower airways of mechanically ventilated COVID-19 patients associated with poor clinical outcome Sulaiman, I; Chung, M; Angel, L et al. Nat Microbiol, DOI://10.1038/s41564-021-00961-5 (2021)
- Longitudinal change in blood DNA epigenetic signature after smoking cessation Keshawarz, A; Joehanes, R; Guan, W et al. Epigenetics, DOI://10.1080/15592294.2021.1985301 (2021)
- Dual Inhibition of Histone Deacetylases and the Mechanistic Target of Rapamycin Promotes Apoptosis in Cell Line Models of Uveal Melanoma Patel, RP; Thomas, JR; Curt, KM et al. Invest Ophthalmol Vis Sci, DOI://10.1167/iovs.62.12.16 (2021)
- The ETS transcription factor ERF controls the exit from the naive pluripotent state in a MAPK-dependent manner Vega-Sendino, M; Olbrich, T; Tillo, D et al. Sci Adv, DOI://10.1126/sciadv.abg8306 (2021)
- Blockade of GRTH/DDX25 Phosphorylation by Cyclic Peptides Provides an Avenue for Developing a Nonhormonal Male Contraceptive Raju, M; Kavarthapu, R; Anbazhagan, R et al. J Med Chem, DOI://10.1021/acs.jmedchem.1c01201 (2021)
- Long term follow-up of a phase II study of cladribine with concurrent rituximab with hairy cell leukemia variant Chihara, D; Arons, E; Stetler-Stevenson, M et al. Blood Adv, DOI://10.1182/bloodadvances.2021005039 (2021)
- Proteogenomic Analysis Unveils the HLA Class I-Presented Immunopeptidome in Melanoma and EGFR-Mutant Lung Adenocarcinoma Qi, YA; Maity, TK; Cultraro, CM et al. Mol Cell Proteomics, DOI://10.1016/j.mcpro.2021.100136 (2021)
- Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action Eren, E; Watts, NR; Sackett, DL; Wingfield, PT; , J Biol Chem, DOI://10.1016/j.jbc.2021.101138 (2021)
- Systematic investigation of cytokine signaling activity at the tissue and single-cell levels Jiang, P; Zhang, Y; Ru, B et al. Nat Methods, DOI://10.1038/s41592-021-01274-5 (2021)
- Phenotypic and Genetic Spectrum of Autosomal Recessive Bestrophinopathy and Best Vitelliform Macular Dystrophy Pfister, TA; Zein, WM; Cukras, CA et al. Invest Ophthalmol Vis Sci, DOI://10.1167/iovs.62.6.22 (2021)
- The taxonomic distribution of histamine-secreting bacteria in the human gut microbiome Mou, Z; Yang, Y; Hall, AB; Jiang, X; , BMC Genomics, DOI://10.1186/s12864-021-08004-3 (2021)
- A lymphocyte-microglia-astrocyte axis in chronic active multiple sclerosis Absinta, M; Maric, D; Gharagozloo, M et al. Nature, DOI://10.1038/s41586-021-03892-7 (2021)
- Binding of regulatory proteins to nucleosomes is modulated by dynamic histone tails Peng, Y; Li, S; Onufriev, A et al. Nat Commun, DOI://10.1038/s41467-021-25568-6 (2021)
- Joint testing of overall and simple effects for the two-by-two factorial trial design Leifer, ES; Troendle, JF; Kolecki, A; Follmann, DA; , Clin Trials, DOI://10.1177/17407745211014493 (2021)
- Impact of depression and stress on placental DNA methylation in ethnically diverse pregnant women Tesfaye, M; Chatterjee, S; Zeng, X et al. Epigenomics, DOI://10.2217/epi-2021-0192 (2021)
- Altered regulation of DPF3, a member of the SWI/SNF complexes, underlies the 14q24 renal cancer susceptibility locus Colli, LM; Jessop, L; Myers, TA et al. Am J Hum Genet, DOI://10.1016/j.ajhg.2021.07.009 (2021)
- NOTCH-mediated ex vivo expansion of human hematopoietic stem and progenitor cells by culture under hypoxia Araki, D; Fu, JF; Huntsman, H et al. Stem Cell Reports, DOI://10.1016/j.stemcr.2021.08.001 (2021)
- Specific β-Defensins Stimulate Pruritus through Activation of Sensory Neurons Tseng, PY; Hoon, MA; , J Invest Dermatol, DOI://10.1016/j.jid.2021.07.178 (2021)
- Transcriptomic profiling in canines and humans reveals cancer specific gene modules and biological mechanisms common to both species Tawa, GJ; Braisted, J; Gerhold, D et al. PLoS Comput Biol, DOI://10.1371/journal.pcbi.1009450 (2021)
- Genome-Wide Analysis Unveils DNA Helicase RECQ1 as a Regulator of Estrogen Response Pathway in Breast Cancer Cells Lu, X; Redon, CE; Tang, W et al. Mol Cell Biol, DOI://10.1128/MCB.00515-20 (2021)
- Training Spiking Neural Networks in the Strong Coupling Regime Kim, CM; Chow, CC; , Neural Comput, DOI://10.1162/neco_a_01379 (2021)
- Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium Shern, JF; Selfe, J; Izquierdo, E et al. J Clin Oncol, DOI://10.1200/JCO.20.03060 (2021)
- An engineered IL-2 partial agonist promotes CD8 + T cell stemness Mo, F; Yu, Z; Li, P et al. Nature, DOI://10.1038/s41586-021-03861-0 (2021)
- Progesterone promotes immunomodulation and tumor development in the murine mammary gland Werner, LR; Gibson, KA; Goodman, ML et al. J Immunother Cancer, DOI://10.1136/jitc-2020-001710 (2021)
- Stem-like cells drive NF1-associated MPNST functional heterogeneity and tumor progression Sun, D; Xie, XP; Zhang, X et al. Cell Stem Cell, DOI://10.1016/j.stem.2021.04.029 (2021)
- Tumor metabolism and associated serum metabolites define prognostic subtypes of Asian hepatocellular carcinoma Pomyen, Y; Budhu, A; Chaisaingmongkol, J et al. Sci Rep, DOI://10.1038/s41598-021-91560-1 (2021)
- Identification of bacteria-derived HLA-bound peptides in melanoma Kalaora, S; Nagler, A; Nejman, D et al. Nature, DOI://10.1038/s41586-021-03368-8 (2021)
- A clinically applicable integrative molecular classification of meningiomas Nassiri, F; Liu, J; Patil, V et al. Nature, DOI://10.1038/s41586-021-03850-3 (2021)
- CBFB cooperates with p53 to maintain TAp73 expression and suppress breast cancer Malik, N; Yan, H; Yang, HH et al. PLoS Genet, DOI://10.1371/journal.pgen.1009553 (2021)
- Fully-Automated Deep Learning Tool for Sarcopenia Assessment on CT: L1 Versus L3 Vertebral Level Muscle Measurements for Opportunistic Prediction of Adverse Clinical Outcomes Pickhardt, PJ; Perez, AA; Garrett, JW et al. AJR Am J Roentgenol, DOI://10.2214/AJR.21.26486 (2021)
- Identification and Validation of T-cell Receptors Targeting RAS Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy Levin, N; Paria, BC; Vale, NR et al. Clin Cancer Res, DOI://10.1158/1078-0432.CCR-21-0849 (2021)
- Chromosome 8 gain is associated with high-grade transformation in MPNST Dehner, C; Moon, CI; Zhang, X et al. JCI Insight, DOI://10.1172/jci.insight.146351 (2021)
- Replication of the Mammalian Genome by Replisomes Specific for Euchromatin and Heterochromatin Zhang, J; Bellani, MA; Huang, J et al. Front Cell Dev Biol, DOI://10.3389/fcell.2021.729265 (2021)
- Identifying and characterizing virus-encoded circular RNAs Tagawa, T; Kopardé, VN; Ziegelbauer, JM; , Methods, DOI://10.1016/j.ymeth.2021.03.004 (2021)
- Two mechanisms of chromosome fragility at replication-termination sites in bacteria Mei, Q; Fitzgerald, DM; Liu, J et al. Sci Adv, DOI://10.1126/sciadv.abe2846 (2021)
- Dual PD-L1 and TGF-b blockade in patients with recurrent respiratory papillomatosis Robbins, Y; Friedman, J; Clavijo, PE et al. J Immunother Cancer, DOI://10.1136/jitc-2021-003113 (2021)
- Treatment of Relapsing HPV Diseases by Restored Function of Natural Killer Cells Lisco, A; Hsu, AP; Dimitrova, D et al. N Engl J Med, DOI://10.1056/NEJMoa2102715 (2021)
- Biomedical Vocabulary Alignment at Scale in the UMLS Metathesaurus Nguyen, V; Yip, HY; Bodenreider, O; , Proc Int World Wide Web Conf, DOI://10.1145/3442381.3450128 (2021)
- The third-generation EGFR inhibitor almonertinib (HS-10296) resensitizes ABCB1-overexpressing multidrug-resistant cancer cells to chemotherapeutic drugs Wu, CP; Hung, TH; Lusvarghi, S et al. Biochem Pharmacol, DOI://10.1016/j.bcp.2021.114516 (2021)
- Compromised counterselection by FAS creates an aggressive subtype of germinal center lymphoma Razzaghi, R; Agarwal, S; Kotlov, N et al. J Exp Med, DOI://10.1084/jem.20201173 (2021)
- Regulation of the Dimerization and Activity of SARS-CoV-2 Main Protease through Reversible Glutathionylation of Cysteine 300 Davis, DA; Bulut, H; Shrestha, P et al. mBio, DOI://10.1128/mBio.02094-21 (2021)
- Gut microbiota development during infancy: Impact of introducing allergenic foods Marrs, T; Jo, JH; Perkin, MR et al. J Allergy Clin Immunol, DOI://10.1016/j.jaci.2020.09.042 (2021)
- Immune cell deconvolution of bulk DNA methylation data reveals an association with methylation class, key somatic alterations, and cell state in glial/glioneuronal tumors Singh, O; Pratt, D; Aldape, K; , Acta Neuropathol Commun, DOI://10.1186/s40478-021-01249-9 (2021)
- Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing Xiao, W; Ren, L; Chen, Z et al. Nat Biotechnol, DOI://10.1038/s41587-021-00994-5 (2021)
- Skin Metagenomic Sequence Analysis of Early Candida auris Outbreaks in U.S. Nursing Homes Huang, X; Welsh, RM; Deming, C et al. mSphere, DOI://10.1128/mSphere.00287-21 (2021)
- Applications of genetic-epigenetic tissue mapping for plasma DNA in prenatal testing, transplantation and oncology Gai, W; Zhou, Z; Agbor-Enoh, S et al. Elife, DOI://10.7554/eLife.64356 (2021)
- Toward Reducing hERG Affinities for DAT Inhibitors with a Combined Machine Learning and Molecular Modeling Approach Lee, KH; Fant, AD; Guo, J et al. J Chem Inf Model, DOI://10.1021/acs.jcim.1c00856 (2021)
- Identification of human long noncoding RNAs associated with nonalcoholic fatty liver disease and metabolic homeostasis Ruan, X; Li, P; Ma, Y et al. J Clin Invest, DOI://10.1172/JCI136336 (2021)
- Magnetization transfer weighted EPI facilitates cortical depth determination in native fMRI space Chai, Y; Li, L; Wang, Y et al. Neuroimage, DOI://10.1016/j.neuroimage.2021.118455 (2021)
- ZFTA Translocations Constitute Ependymoma Chromatin Remodeling and Transcription Factors Kupp, R; Ruff, L; Terranova, S et al. Cancer Discov, DOI://10.1158/2159-8290.CD-20-1052 (2021)
- Tobacco smoking induces metabolic reprogramming of renal cell carcinoma Reigle, J; Secic, D; Biesiada, J et al. J Clin Invest, DOI://10.1172/JCI140522 (2021)
- Understanding tumour cell heterogeneity and its implication for immunotherapy in liver cancer using single-cell analysis Heinrich, S; Craig, AJ; Ma, L et al. J Hepatol, DOI://10.1016/j.jhep.2020.11.036 (2021)
- A penalized regression framework for building polygenic risk models based on summary statistics from genome-wide association studies and incorporating external information Chen, TH; Chatterjee, N; Landi, MT; Shi, J; , J Am Stat Assoc, DOI://10.1080/01621459.2020.1764849 (2021)
- Differences in risk factors for molecular subtypes of clear cell renal cell carcinoma Purdue, MP; Rhee, J; Moore, L et al. Int J Cancer, DOI://10.1002/ijc.33701 (2021)
- A Novel ARL3 Gene Mutation Associated With Autosomal Dominant Retinal Degeneration Ratnapriya, R; Jacobson, SG; Cideciyan, AV et al. Front Cell Dev Biol, DOI://10.3389/fcell.2021.720782 (2021)
- Determinants of conductance of a bacterial voltage-gated sodium channel Chen, AY; Brooks, BR; Damjanovic, A; , Biophys J, DOI://10.1016/j.bpj.2021.06.013 (2021)
- Genetic risk scores for cardiometabolic traits in sub-Saharan African populations Ekoru, K; Adeyemo, AA; Chen, G et al. Int J Epidemiol, DOI://10.1093/ije/dyab046 (2021)
- Cell-free DNA ultra-low-pass whole genome sequencing to distinguish malignant peripheral nerve sheath tumor (MPNST) from its benign precursor lesion: A cross-sectional study Szymanski, JJ; Sundby, RT; Jones, PA et al. PLoS Med, DOI://10.1371/journal.pmed.1003734 (2021)
- SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity Olia, AS; Tsybovsky, Y; Chen, SJ et al. J Biol Chem, DOI://10.1016/j.jbc.2021.101127 (2021)
- Ras isoform-specific expression, chromatin accessibility, and signaling Nussinov, R; Zhang, M; Maloney, R; Jang, H; , Biophys Rev, DOI://10.1007/s12551-021-00817-6 (2021)
- Prenatal maternal infection promotes tissue-specific immunity and inflammation in offspring Lim, AI; McFadden, T; Link, VM et al. Science, DOI://10.1126/science.abf3002 (2021)
- Identification of natural product modulators of Merkel cell carcinoma cell growth and survival Smith, EA; Hill, NT; Gelb, T et al. Sci Rep, DOI://10.1038/s41598-021-93097-9 (2021)
- A linear noise approximation for stochastic epidemic models fit to partially observed incidence counts Fintzi, J; Wakefield, J; Minin V Biometrics, 10.1111/biom.13538 (2021)
- X-chromosome influences on neuroanatomical variation in humans Mallard, TT; Liu, S; Seidlitz, J et al. Nat Neurosci, DOI://10.1038/s41593-021-00890-w (2021)
- Topographical and laminar distribution of audiovisual processing within human planum temporale Chai, Y; Liu, TT; Marrett, S et al. Prog Neurobiol, DOI://10.1016/j.pneurobio.2021.102121 (2021)
- Origin of the Isomer Stability of Polymethylated DOTA Chelates Complexed with Ln3+ Ions Yong-Sok Lee, Zhongyou Mou et al Eur. J. Inorg. Chem, doi://10.1002/ejic.202100252 (2021)
- Empirical Findings on the Role of Structured Data, Unstructured Data, and their Combination for Automatic Clinical Phenotyping Moldwin, A; Demner-Fushman, D; Goodwin, TR; , AMIA Annu Symp Proc, 1942-597X (2021)
- The trans-ancestral genomic architecture of glycemic traits Chen, J; Spracklen, CN; Marenne, G et al. Nat Genet, DOI://10.1038/s41588-021-00852-9 (2021)
- Compound heterozygous KCTD7 variants in progressive myoclonus epilepsy Burke, EA; Sturgeon, M; Zastrow, DB et al. J Neurogenet, DOI://10.1080/01677063.2021.1892095 (2021)
- Genetic contributions to alcohol use disorder treatment outcomes: a genome-wide pharmacogenomics study Biernacka, JM; Coombes, BJ; Batzler, A et al. Neuropsychopharmacology, DOI://10.1038/s41386-021-01097-0 (2021)
- The N terminus of α-synuclein dictates fibril formation McGlinchey, RP; Ni, X; Shadish, JA et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2023487118 (2021)
- Hedgehog dysregulation contributes to tissue-specific inflammaging of resident macrophages Babagana, M; Oh, KS; Chakraborty, S et al. Aging (Albany NY), DOI://10.18632/aging.203422 (2021)
- Recovering prokaryotic genomes from host-associated, short-read shotgun metagenomic sequencing data Saheb Kashaf, S; Almeida, A; Segre, JA; Finn, RD; , Nat Protoc, DOI://10.1038/s41596-021-00508-2 (2021)
- Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging McCartney, DL; Min, JL; Richmond, RC et al. Genome Biol, DOI://10.1186/s13059-021-02398-9 (2021)
- Effects of processed meat and drinking water nitrate on oral and fecal microbial populations in a controlled feeding study Sinha, R; Zhao, N; Goedert, JJ et al. Environ Res, DOI://10.1016/j.envres.2021.111084 (2021)
- Dynamic Time Warping Identifies Functionally Distinct fMRI Resting State Cortical Networks Specific to VTA and SNc: A Proof of Concept Philips, RT; Torrisi, SJ; Gorka, AX et al. Cereb Cortex, DOI://10.1093/cercor/bhab273 (2021)
- Rat PRDM9 shapes recombination landscapes, duration of meiosis, gametogenesis, and age of fertility Mihola, O; Landa, V; Pratto, F et al. BMC Biol, DOI://10.1186/s12915-021-01017-0 (2021)
- Amygdala Functional Connectivity and Negative Reactive Temperament at Age 4 Months Filippi, CA; Ravi, S; Bracy, M et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2020.11.021 (2021)
- Sperm acrosome overgrowth and infertility in mice lacking chromosome 18 pachytene piRNA Choi, H; Wang, Z; Dean, J; , PLoS Genet, DOI://10.1371/journal.pgen.1009485 (2021)
- Intratumoral γδ T-Cell Infiltrates, Chemokine (C-C Motif) Ligand 4/Chemokine (C-C Motif) Ligand 5 Protein Expression and Survival in Patients With Hepatocellular Carcinoma Zhao, N; Dang, H; Ma, L et al. Hepatology, DOI://10.1002/hep.31412 (2021)
- FOXF1 is required for the oncogenic properties of PAX3-FOXO1 in rhabdomyosarcoma Milewski, D; Shukla, S; Gryder, BE et al. Oncogene, DOI://10.1038/s41388-021-01694-9 (2021)
- Single-cell atlas of tumor cell evolution in response to therapy in hepatocellular carcinoma and intrahepatic cholangiocarcinoma Ma, L; Wang, L; Khatib, SA et al. J Hepatol, DOI://10.1016/j.jhep.2021.06.028 (2021)
- High-resolution structure and strain comparison of infectious mammalian prions Kraus, A; Hoyt, F; Schwartz, CL et al. Mol Cell, DOI://10.1016/j.molcel.2021.08.011 (2021)
- Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants Xu, J; Xu, K; Jung, S et al. Nature, DOI://10.1038/s41586-021-03676-z (2021)
- Novel Tsg101 Binding Partners Regulate Viral L Domain Trafficking Strickland, M; Nyenhuis, D; Watanabe, SM et al. Viruses, DOI://10.3390/v13061147 (2021)
- An Integrative Genomic Strategy Identifies sRAGE as a Causal and Protective Biomarker of Lung Function Keefe, J; Yao, C; Hwang, SJ et al. Chest, DOI://10.1016/j.chest.2021.06.053 (2021)
- Bias correction for estimates from linear excess relative risk models in small case-control studies Roberti, S; van Leeuwen, FE; Hauptmann, M; Pfeiffer, RM; , Stat Med, DOI://10.1002/sim.9158 (2021)
- Regional White Matter Scaling in the Human Brain Warling, A; McDermott, CL; Liu, S et al. J Neurosci, DOI://10.1523/JNEUROSCI.1193-21.2021 (2021)
- Experimental Babesia rossi infection induces hemolytic, metabolic, and viral response pathways in the canine host Smith, RL; Goddard, A; Boddapati, A et al. BMC Genomics, DOI://10.1186/s12864-021-07889-4 (2021)
- Granzyme A and CD160 expression delineates ILC1 with graded functions in the mouse liver Di Censo, C; Marotel, M; Mattiola, I et al. Eur J Immunol, DOI://10.1002/eji.202149209 (2021)
- Mechanistic basis of breast cancer resistance protein inhibition by new indeno[1,2-b]indoles Kita, DH; Guragossian, N; Zattoni, IF et al. Sci Rep, DOI://10.1038/s41598-020-79892-w (2021)
- POLD1 Deficiency Reveals a Role for POLD1 in DNA Repair and T and B Cell Development Nichols-Vinueza, DX; Delmonte, OM; Bundy, V et al. J Clin Immunol, DOI://10.1007/s10875-020-00903-6 (2021)
- Genome-wide covariation in SARS-CoV-2 Cresswell-Clay, E; Periwal, V; , Math Biosci, DOI://10.1016/j.mbs.2021.108678 (2021)
- Atomic view of cosolute-induced protein denaturation probed by NMR solvent paramagnetic relaxation enhancement Okuno, Y; Yoo, J; Schwieters, CD et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2112021118 (2021)
- Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding Han, S; Okawa, S; Wilkinson, GA et al. Neuron, DOI://10.1016/j.neuron.2021.07.007 (2021)
- Fecal microbiota transplant overcomes resistance to anti-PD-1 therapy in melanoma patients Davar, D; Dzutsev, AK; McCulloch, JA et al. Science, DOI://10.1126/science.abf3363 (2021)
- Sclerosing Sialadenitis Is Associated With Salivary Gland Hypofunction and a Unique Gene Expression Profile in Sjögren's Syndrome Yin H, Pranzatelli TJF et al. Front Immunol ., doi://10.3389/fimmu.2021.699722. (2021)
- The large bat Helitron DNA transposase forms a compact monomeric assembly that buries and protects its covalently bound 5'-transposon end Kosek, D; Grabundzija, I; Lei, H et al. Mol Cell, DOI://10.1016/j.molcel.2021.07.028 (2021)
- Identification of Accessible Hepatic Gene Signatures for Interindividual Variations in Nutrigenomic Response to Dietary Supplementation of Omega-3 Fatty Acids Shi, Y; Li, P; Jiang, CF et al. Cells, DOI://10.3390/cells10020467 (2021)
- Mouse papillomavirus type 1 (MmuPV1) DNA is frequently integrated in benign tumors by microhomology-mediated end-joining Yu, L; Majerciak, V; Xue, XY et al. PLoS Pathog, DOI://10.1371/journal.ppat.1009812 (2021)
- RGC-32 Acts as a Hub to Regulate the Transcriptomic Changes Associated With Astrocyte Development and Reactive Astrocytosis Tatomir, A; Beltrand, A; Nguyen, V et al. Front Immunol, DOI://10.3389/fimmu.2021.705308 (2021)
- Identification of retinal ganglion cell types and brain nuclei expressing the transcription factor Brn3c/Pou4f3 using a Cre recombinase knock-in allele Parmhans, N; Fuller, AD; Nguyen, E et al. J Comp Neurol, DOI://10.1002/cne.25065 (2021)
- Hepcidin-regulating iron metabolism genes and pancreatic ductal adenocarcinoma: a pathway analysis of genome-wide association studies Julián-Serrano, S; Yuan, F; Wheeler, W et al. Am J Clin Nutr, DOI://10.1093/ajcn/nqab217 (2021)
- JAK inhibitors dampen activation of interferon-activated transcriptomes and the SARS-CoV-2 receptor ACE2 in human renal proximal tubules Jankowski, J; Lee, HK; Wilflingseder, J; Hennighausen, L; , iScience, DOI://10.1016/j.isci.2021.102928 (2021)
- Color Space Geometry Uncovered with Magnetoencephalography Rosenthal, IA; Singh, SR; Hermann, KL et al. Curr Biol, DOI://10.1016/j.cub.2021.02.023 (2021)
- Novel Majeed Syndrome-Causing LPIN2 Mutations Link Bone Inflammation to Inflammatory M2 Macrophages and Accelerated Osteoclastogenesis Bhuyan, F; de Jesus, AA; Mitchell, J et al. Arthritis Rheumatol, DOI://10.1002/art.41624 (2021)
- The X-linked acrogigantism-associated gene gpr101 is a regulator of early embryonic development and growth in zebrafish Trivellin, G; Tirosh, A; Hernández-Ramírez, LC et al. Mol Cell Endocrinol, DOI://10.1016/j.mce.2020.111091 (2021)
- How to Interpret Resting-State fMRI: Ask Your Participants Gonzalez-Castillo, J; Kam, JWY; Hoy, CW; Bandettini, PA; , J Neurosci, DOI://10.1523/JNEUROSCI.1786-20.2020 (2021)
- RepairSig: Deconvolution of DNA damage and repair contributions to the mutational landscape of cancer Wojtowicz, D; Hoinka, J; Amgalan, B et al. Cell Syst, DOI://10.1016/j.cels.2021.07.004 (2021)
- Contrasting Patterns of Gene Duplication, Relocation, and Selection Among Human Taste Genes Wang, Y; Sun, Y; Joseph, PV; , Evol Bioinform Online, DOI://10.1177/11769343211035141 (2021)
- Translational autoregulation of the S. cerevisiae high-affinity polyamine transporter Hol1 Vindu, A; Shin, BS; Choi, K et al. Mol Cell, DOI://10.1016/j.molcel.2021.07.020 (2021)
- A phage-encoded nucleoid associated protein compacts both host and phage DNA and derepresses H-NS silencing Son, B; Patterson-West, J; Arroyo-Mendoza, M et al. Nucleic Acids Res, DOI://10.1093/nar/gkab678 (2021)
- Branebrutinib (BMS-986195), a Bruton'ss Tyrosine Kinase Inhibitor, Resensitizes P-Glycoprotein-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Agents Wu, CP; Murakami, M; Wu, YS et al. Front Cell Dev Biol, DOI://10.3389/fcell.2021.699571 (2021)
- Distinct Mitochondrial Pathologies Caused by Mutations of the Proximal Tubular Enzymes EHHADH and GATM Forst, AL; Reichold, M; Kleta, R; Warth, R; , Front Physiol, DOI://10.3389/fphys.2021.715485 (2021)
- Use of Variational Autoencoders with Unsupervised Learning to Detect Incorrect Organ Segmentations at CT Sandfort, V; Yan, K; Graffy, PM et al. Radiol Artif Intell, DOI://10.1148/ryai.2021200218 (2021)
- gEAR: Gene Expression Analysis Resource portal for community-driven, multi-omic data exploration Orvis, J; Gottfried, B; Kancherla, J et al. Nat Methods, DOI://10.1038/s41592-021-01200-9 (2021)
- Endemic Burkitt Lymphoma in second-degree relatives in Northern Uganda: in-depth genome-wide analysis suggests clues about genetic susceptibility Gouveia, MH; Otim, I; Ogwang, MD et al. Leukemia, DOI://10.1038/s41375-020-01052-w (2021)
- Linking cortical circuit models to human cognition with laminar fMRI Yang, J; Huber, L; Yu, Y; Bandettini, PA; , Neurosci Biobehav Rev, DOI://10.1016/j.neubiorev.2021.07.005 (2021)
- Serine hydroxymethyltransferase 2 expression promotes tumorigenesis in rhabdomyosarcoma with 12q13-q14 amplification Nguyen, TH; Vemu, PL; Hoy, GE et al. J Clin Invest, DOI://10.1172/JCI138022 (2021)
- Aberrant type 1 immunity drives susceptibility to mucosal fungal infections Break, TJ; Oikonomou, V; Dutzan, N et al. Science, DOI://10.1126/science.aay5731 (2021)
- The p53-induced RNA-binding protein ZMAT3 is a splicing regulator that inhibits the splicing of oncogenic CD44 variants in colorectal carcinoma Muys, BR; Anastasakis, DG; Claypool, D et al. Genes Dev, DOI://10.1101/gad.342634.120 (2021)
- Host-Virus Chimeric Events in SARS-CoV-2-Infected Cells Are Infrequent and Artifactual Yan, B; Chakravorty, S; Mirabelli, C et al. J Virol, DOI://10.1128/JVI.00294-21 (2021)
- Direct identification of neoantigen-specific TCRs from tumor specimens by high-throughput single-cell sequencing Lu, YC; Zheng, Z; Lowery, FJ et al. J Immunother Cancer, DOI://10.1136/jitc-2021-002595 (2021)
- Resting-State Functional Connectivity and Psychopathology in Klinefelter Syndrome (47, XXY) Whitman, ET; Liu, S; Torres, E et al. Cereb Cortex, DOI://10.1093/cercor/bhab077 (2021)
- A computational network perspective on pediatric anxiety symptoms Abend, R; Bajaj, MA; Coppersmith, DDL et al. Psychol Med, DOI://10.1017/S0033291720000501 (2021)
- Strengths and challenges of longitudinal non-human primate neuroimaging Song, X; García-Saldivar, P; Kindred, N et al. Neuroimage, DOI://10.1016/j.neuroimage.2021.118009 (2021)
- NLM-Gene, a richly annotated gold standard dataset for gene entities that addresses ambiguity and multi-species gene recognition Islamaj, R; Wei, CH; Cissel, D et al. J Biomed Inform, DOI://10.1016/j.jbi.2021.103779 (2021)
- Shifts in the Skin Bacterial and Fungal Communities of Healthy Children Transitioning through Puberty Park, J; Schwardt, NH; Jo, JH et al. J Invest Dermatol, DOI://10.1016/j.jid.2021.04.034 (2021)
- Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA Ma, R; Lian, T; Huang, R et al. Nat Microbiol, DOI://10.1038/s41564-020-00858-9 (2021)
- Unusual phenotypes in patients with a pathogenic germline variant in DICER1 Venger, K; Elbracht, M; Carlens, J et al. Fam Cancer, DOI://10.1007/s10689-021-00271-z (2021)
- Clinical Manifestations, Mutational Analysis, and Immunological Phenotype in Patients with RAG1/2 Mutations: First Cases Series from Mexico and Description of Two Novel Mutations Lugo-Reyes, SO; Pastor, N; González-Serrano, E et al. J Clin Immunol, DOI://10.1007/s10875-021-01052-0 (2021)
- Distinguishing type II focal cortical dysplasias from normal cortex: A novel normative modeling approach Snyder, K; Whitehead, EP; Theodore, WH et al. Neuroimage Clin, DOI://10.1016/j.nicl.2021.102565 (2021)
- The genome of the stable fly, Stomoxys calcitrans, reveals potential mechanisms underlying reproduction, host interactions, and novel targets for pest control Olafson, PU; Aksoy, S; Attardo, GM et al. BMC Biol, DOI://10.1186/s12915-021-00975-9 (2021)
- Toward a Liver Cell Atlas: Understanding Liver Biology in Health and Disease at Single-Cell Resolution Ma, L; Khatib, S; Craig, AJ; Wang, XW; , Semin Liver Dis, DOI://10.1055/s-0041-1729970 (2021)
- Mutant Idh2 cooperates with a NUP98-HOXD13 fusion to induce early immature thymocyte precursor ALL Goldberg, L; Negi, V; Chung, YJ et al. Cancer Res, DOI://10.1158/0008-5472.CAN-21-1027 (2021)
- Gene-Based Association Testing of Dichotomous Traits With Generalized Functional Linear Mixed Models Using Extended Pedigrees: Applications to Age-Related Macular Degeneration Jiang, Y; Chiu, CY; Yan, Q et al. J Am Stat Assoc, DOI://10.1080/01621459.2020.1799809 (2021)
- Acute ambient air pollution exposure and placental Doppler results in the NICHD fetal growth studies - Singleton cohort Ouidir, M; Tekola-Ayele, F; Canty, T et al. Environ Res, DOI://10.1016/j.envres.2021.111728 (2021)
- Monocyte Subsets With High Osteoclastogenic Potential and Their Epigenetic Regulation Orchestrated by IRF8 Das, A; Wang, X; Kang, J et al. J Bone Miner Res, DOI://10.1002/jbmr.4165 (2021)
- Emotional distractors and attentional control in anxious youth: eye tracking and fMRI data Smith, AR; Haller, SP; Haas, SA et al. Cogn Emot, DOI://10.1080/02699931.2020.1816911 (2021)
- Endogenous retroviruses drive lineage-specific regulatory evolution across primate and rodent placentae Sun, MA; Wolf, G; Wang, Y et al. Mol Biol Evol, DOI://10.1093/molbev/msab223 (2021)
- Roseabol A, a New Peptaibol from the Fungus Clonostachys rosea Kim, CK; Krumpe, LRH; Smith, E et al. Molecules, DOI://10.3390/molecules26123594 (2021)
- Frequency of Pathogenic Germline Variants in Cancer-Susceptibility Genes in the Childhood Cancer Survivor Study Kim, J; Gianferante, M; Karyadi, DM et al. JNCI Cancer Spectr, DOI://10.1093/jncics/pkab007 (2021)
- In vivo evolution of an emerging zoonotic bacterial pathogen in an immunocompromised human host Launay, A; Wu, CJ; Dulanto Chiang, A et al. Nat Commun, DOI://10.1038/s41467-021-24668-7 (2021)
- A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids Jhun, MA; Mendelson, M; Wilson, R et al. Nat Commun, DOI://10.1038/s41467-021-23899-y (2021)
- PD-1 blockade exacerbates Mycobacterium tuberculosis infection in rhesus macaques Kauffman, KD; Sakai, S; Lora, NE et al. Sci Immunol, DOI://10.1126/sciimmunol.abf3861 (2021)
- Publisher Correction: A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids Jhun, MA; Mendelson, M; Wilson, R et al. Nat Commun, DOI://10.1038/s41467-021-24600-z (2021)
- M1BP cooperates with CP190 to activate transcription at TAD borders and promote chromatin insulator activity Bag, I; Chen, S; Rosin, LF et al. Nat Commun, DOI://10.1038/s41467-021-24407-y (2021)
- Oncogenic Hedgehog-smoothened signaling depends on YAP1-TAZ/TEAD transcription to restrain differentiation in basal cell carcinoma Yuan, Y; Salinas Parra, N; Chen, Q; Iglesias-Bartolome, R; , J Invest Dermatol, DOI://10.1016/j.jid.2021.06.020 (2021)
- Targeting a noncanonical, hairpin-containing G-quadruplex structure from the MYCN gene Yang, M; Carter, S; Parmar, S et al. Nucleic Acids Res, DOI://10.1093/nar/gkab594 (2021)
- Budding epithelial morphogenesis driven by cell-matrix versus cell-cell adhesion Wang, S; Matsumoto, K; Lish, SR et al. Cell, DOI://10.1016/j.cell.2021.05.015 (2021)
- Modelling PNPLA3-Associated Non-Alcoholic Fatty Liver Disease Using Human Induced Pluripotent Stem Cells Tilson, SG; Morell, CM; Lenaerts, AS et al. Hepatology, DOI://10.1002/hep.32063 (2021)
- Statistical learning occurs during practice while high-order rule learning during rest period Quentin, R; Fanuel, L; Kiss, M et al. NPJ Sci Learn, DOI://10.1038/s41539-021-00093-9 (2021)
- A Randomized Controlled Trial of Computerized Interpretation Bias Training for Disruptive Mood Dysregulation Disorder: A Fast-Fail Study Haller, SP; Stoddard, J; Botz-Zapp, C et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2021.05.022 (2021)
- Characterizing Expression and Regulation of Gamma-Herpesviral Circular RNAs Tagawa, T; Oh, D; Santos, J et al. Front Microbiol, DOI://10.3389/fmicb.2021.670542 (2021)
- The dystonia gene THAP1 controls DNA double-strand break repair choice Shinoda, K; Zong, D; Callen, E et al. Mol Cell, DOI://10.1016/j.molcel.2021.03.034 (2021)
- PARK7-Related Early Onset Parkinson Disease in the Setting of Complete Uniparental Isodisomy of Chromosome 1 Xiao, C; Markello, T; Zein, WM et al. Neurol Genet, DOI://10.1212/NXG.0000000000000606 (2021)
- Genetic and evolutionary analysis of SARS-CoV-2 circulating in the region surrounding Islamabad, Pakistan Tamim, S; Trovao, NS; Thielen, P et al. Infect Genet Evol, DOI://10.1016/j.meegid.2021.105003 (2021)
- Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry Graff, M; Justice, AE; Young, KL et al. Am J Hum Genet, DOI://10.1016/j.ajhg.2021.02.011 (2021)
- A fluorescence-based genetic screen reveals diverse mechanisms silencing small RNA signaling in E. coli Chen, J; To, L; de Mets, F et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2106964118 (2021)
- Computational Modeling of C-Terminal Tails to Predict the Calcium-Dependent Secretion of Endoplasmic Reticulum Resident Proteins Trychta, KA; Xie, B; Verma, RK et al. Front Chem, DOI://10.3389/fchem.2021.689608 (2021)
- Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease Tumburu, L; Ghosh-Choudhary, S; Seifuddin, FT et al. Blood, DOI://10.1182/blood.2020009063 (2021)
- Multimodal Molecular Imaging Detects Early Responses to Immune Checkpoint Blockade Saida, Y; Brender, JR; Yamamoto, K et al. Cancer Res, DOI://10.1158/0008-5472.CAN-20-3182 (2021)
- Landscape of GPCR expression along the mouse nephron Poll, BG; Chen, L; Chou, CL et al. Am J Physiol Renal Physiol, DOI://10.1152/ajprenal.00077.2021 (2021)
- Activation of the antiviral factor RNase L triggers translation of non-coding mRNA sequences Karasik, A; Jones, GD; DePass, AV; Guydosh, NR; , Nucleic Acids Res, DOI://10.1093/nar/gkab036 (2021)
- Fine-tuning neural excitation/inhibition for tailored ketamine use in treatment-resistant depression Fagerholm, ED; Leech, R; Williams, S et al. Transl Psychiatry, DOI://10.1038/s41398-021-01442-3 (2021)
- Meiotic recombination mirrors patterns of germline replication in mice and humans Pratto, F; Brick, K; Cheng, G et al. Cell, DOI://10.1016/j.cell.2021.06.025 (2021)
- Prior Cocaine Use Alters the Normal Evolution of Information Coding in Striatal Ensembles during Value-Guided Decision-Making Mueller, LE; Sharpe, MJ; Stalnaker, TA et al. J Neurosci, DOI://10.1523/JNEUROSCI.1755-20.2020 (2021)
- A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells Chen, Y; Tristan, CA; Chen, L et al. Nat Methods, DOI://10.1038/s41592-021-01126-2 (2021)
- Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer Roper, N; Velez, MJ; Chiappori, A et al. Nat Commun, DOI://10.1038/s41467-021-24164-y (2021)
- The combined action of CTCF and its testis-specific paralog BORIS is essential for spermatogenesis Rivero-Hinojosa, S; Pugacheva, EM; Kang, S et al. Nat Commun, DOI://10.1038/s41467-021-24140-6 (2021)
- Analysis of PTRHD1 common and rare variants in European patients with Parkinson's disease Sosero, YL; Bandres-Ciga, S; Gan-Or, Z et al. Neurobiol Aging, DOI://10.1016/j.neurobiolaging.2021.06.005 (2021)
- Navigator-Guided Motion and B0 Correction of T2*-Weighted Magnetic Resonance Imaging Improves Multiple Sclerosis Cortical Lesion Detection Liu, J; Beck, ES; Filippini, S et al. Invest Radiol, DOI://10.1097/RLI.0000000000000754 (2021)
- Retbindin mediates light-damage in mouse retina while its absence leads to premature retinal aging Fan, J; Rajapakse, D; Peterson, K et al. Exp Eye Res, DOI://10.1016/j.exer.2021.108698 (2021)
- Personalized Single-Cell Proteogenomics to Distinguish Acute Myeloid Leukemia from Nonmalignant Clonal Hematopoiesis Dillon, LW; Ghannam, J; Nosiri, C et al. Cancer Discov, DOI://10.1158/2643-3230.BCD-21-0046 (2021)
- The structures of two salivary proteins from the West Nile vector Culex quinquefasciatus reveal a beta-trefoil fold with putative sugar binding properties Kern, O; Valenzuela Leon, PC; Gittis, AG et al. Curr Res Struct Biol, DOI://10.1016/j.crstbi.2021.03.001 (2021)
- Histone tails as signaling antennas of chromatin Peng, Y; Li, S; Landsman, D; Panchenko, AR; , Curr Opin Struct Biol, DOI://10.1016/j.sbi.2020.10.018 (2021)
- A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis Disatham, J; Brennan, L; Chauss, D et al. BMC Genomics, DOI://10.1186/s12864-021-07795-9 (2021)
- Consolidation of human skill linked to waking hippocampo-neocortical replay Buch, ER; Claudino, L; Quentin, R et al. Cell Rep, DOI://10.1016/j.celrep.2021.109193 (2021)
- The Parkinson's Disease DNA Variant Browser Kim, JJ; Makarious, MB; Bandres-Ciga, S et al. Mov Disord, DOI://10.1002/mds.28488 (2021)
- Genetic Variation and Recurrent Haplotypes on Chromosome 6q23-25 Risk Locus in Familial Lung Cancer Musolf, AM; Simpson, CL; Moiz, BA et al. Cancer Res, DOI://10.1158/0008-5472.CAN-20-3196 (2021)
- LayNii: A software suite for layer-fMRI Huber, LR; Poser, BA; Bandettini, PA et al. Neuroimage, DOI://10.1016/j.neuroimage.2021.118091 (2021)
- Ketamine and Attentional Bias Toward Emotional Faces: Dynamic Causal Modeling of Magnetoencephalographic Connectivity in Treatment-Resistant Depression Gilbert, JR; Galiano, CS; Nugent, AC; Zarate, CA; , Front Psychiatry, DOI://10.3389/fpsyt.2021.673159 (2021)
- Dynamics of replication origin over-activation Fu, H; Redon, CE; Thakur, BL et al. Nat Commun, DOI://10.1038/s41467-021-23835-0 (2021)
- Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure Wang, H; Noordam, R; Cade, BE et al. Mol Psychiatry, DOI://10.1038/s41380-021-01087-0 (2021)
- CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice Li, N; Torres, MB; Spetz, MR et al. Cell Rep Med, DOI://10.1016/j.xcrm.2021.100297 (2021)
- Assessing vaccine durability in randomized trials following placebo crossover Fintzi, J; Follmann, D; , Stat Med, DOI://10.1002/sim.9001 (2021)
- Predictable fold switching by the SARS-CoV-2 protein ORF9b Porter, LL Protein Sci, DOI://10.1002/pro.4097 (2021)
- The temporal representation of experience in subjective mood Keren, H; Zheng, C; Jangraw, DC et al. Elife, DOI://10.7554/eLife.62051 (2021)
- GWAS in Africans identifies novel lipids loci and demonstrates heterogenous association within Africa Bentley, AR; Chen, G; Doumatey, AP et al. Hum Mol Genet, DOI://10.1093/hmg/ddab174 (2021)
- Distinct Signatures of Genomic Copy Number Variants Define Subgroups of Merkel Cell Carcinoma Tumors Hill, NT; Kim, D; Busam, KJ et al. Cancers (Basel), DOI://10.3390/cancers13051134 (2021)
- Long-term stability of avalanche scaling and integrative network organization in prefrontal and premotor cortex Miller, SR; Yu, S; Pajevic, S; Plenz, D; , Netw Neurosci, DOI://10.1162/netn_a_00188 (2021)
- The mechanism of activation of monomeric B-Raf V600E Maloney, RC; Zhang, M; Jang, H; Nussinov, R; , Comput Struct Biotechnol J, DOI://10.1016/j.csbj.2021.06.007 (2021)
- Functional connectivity of dorsolateral prefrontal cortex predicts cocaine relapse: implications for neuromodulation treatment Zhai, T; Salmeron, BJ; Gu, H et al. Brain Commun, DOI://10.1093/braincomms/fcab120 (2021)
- Commute patterns, residential traffic-related air pollution, and lung cancer risk in the prospective UK Biobank cohort study Wong, JYY; Jones, RR; Breeze, C et al. Environ Int, DOI://10.1016/j.envint.2021.106698 (2021)
- Hidden mover-stayer model for disease progression accounting for misclassified and partially observed diagnostic tests: Application to the natural history of human papillomavirus and cervical precancer Aron, J; Albert, PS; Wentzensen, N; Cheung, LC; , Stat Med, DOI://10.1002/sim.8977 (2021)
- Subgenual cingulate resting regional cerebral blood flow in premenstrual dysphoric disorder: differential regulation by ovarian steroids and preliminary evidence for an association with expression of ESC/E(Z) complex genes Wei, SM; Baller, EB; Martinez, PE et al. Transl Psychiatry, DOI://10.1038/s41398-021-01328-4 (2021)
- Prediction and Validation of Hematopoietic Stem and Progenitor Cell Off-Target Editing in Transplanted Rhesus Macaques AlJanahi, AA; Lazzarotto, CR; Chen, S et al. Mol Ther, DOI://10.1016/j.ymthe.2021.06.016 (2021)
- Innate Immune Memory in Hematopoietic Stem/Progenitor Cells: Myeloid-Biased Differentiation and the Role of Interferon Chen, L; Ozato, K; , Front Immunol, DOI://10.3389/fimmu.2021.621333 (2021)
- A catalog of tens of thousands of viruses from human metagenomes reveals hidden associations with chronic diseases Tisza, MJ; Buck, CB; , Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2023202118 (2021)
- Structural insights into integrin α 5 β 1 opening by fibronectin ligand Schumacher, S; Dedden, D; Nunez, RV et al. Sci Adv, DOI://10.1126/sciadv.abe9716 (2021)
- A Fusion Transcription Factor-Driven Cancer Progresses to a Fusion-Independent Relapse via Constitutive Activation of a Downstream Transcriptional Target Boudjadi, S; Pandey, PR; Chatterjee, B et al. Cancer Res, DOI://10.1158/0008-5472.CAN-20-1613 (2021)
- Prospective representations in rat orbitofrontal ensembles Zhou, J; Zong, W; Jia, C et al. Behav Neurosci, DOI://10.1037/bne0000451 (2021)
- Group testing can improve the cost-efficiency of prospective-retrospective biomarker studies Zhang, W; Zhang, Z; Krushkal, J; Liu, A; , BMC Med Res Methodol, DOI://10.1186/s12874-021-01239-4 (2021)
- Response of human macrophages to gamma radiation is mediated via expression of endogenous retroviruses Mikhalkevich, N; O'Carroll, IP; Tkavc, R et al. PLoS Pathog, DOI://10.1371/journal.ppat.1009305 (2021)
- Integrin αvβ6-TGFβ-SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer Bagati, A; Kumar, S; Jiang, P et al. Cancer Cell, DOI://10.1016/j.ccell.2020.12.001 (2021)
- Functional connectivity during frustration: a preliminary study of predictive modeling of irritability in youth Scheinost, D; Dadashkarimi, J; Finn, ES et al. Neuropsychopharmacology, DOI://10.1038/s41386-020-00954-8 (2021)
- Correction to: Large‑scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease Bandres-Ciga, S; Saez-Atienzar, S; Kim, JJ et al. Acta Neuropathol, DOI://10.1007/s00401-021-02309-z (2021)
- Structural insights of the conserved “priming loop” of hepatitis B virus pre-genomic RNA LeBlanc, RM; Kasprzak, WK; Longhini, AP et al. J Biomol Struct Dyn, DOI://10.1080/07391102.2021.1934544 (2021)
- Integrated genomic, epidemiologic investigation of Candida auris skin colonization in a skilled nursing facility Proctor, DM; Dangana, T; Sexton, DJ et al. Nat Med, DOI://10.1038/s41591-021-01383-w (2021)
- Genetic and in-utero environmental contributions to DNA methylation variation in placenta Chatterjee, S; Ouidir, M; Tekola-Ayele, F; , Hum Mol Genet, DOI://10.1093/hmg/ddab161 (2021)
- Functional Selectivity of a Biased Cannabinoid-1 Receptor (CB 1 R) Antagonist Liu, Z; Iyer, MR; Godlewski, G et al. ACS Pharmacol Transl Sci, DOI://10.1021/acsptsci.1c00048 (2021)
- Corrigendum: Characterizing Adult Cochlear Supporting Cell Transcriptional Diversity Using Single-Cell RNA-Seq: Validation in the Adult Mouse and Translational Implications for the Adult Human Cochlea Hoa, M; Olszewski, R; Li, X et al. Front Mol Neurosci, DOI://10.3389/fnmol.2021.699859 (2021)
- Investigation of Autosomal Genetic Sex Differences in Parkinson's Disease Blauwendraat, C; Iwaki, H; Makarious, MB et al. Ann Neurol, DOI://10.1002/ana.26090 (2021)
- A UGT1A1 variant is associated with serum total bilirubin levels, which are causal for hypertension in African-ancestry individuals Chen, G; Adeyemo, A; Zhou, J et al. NPJ Genom Med, DOI://10.1038/s41525-021-00208-6 (2021)
- Author Correction to: Endemic Burkitt lymphoma in second-degree relatives in Northern Uganda: in-depth genome-wide analysis suggests clues about genetic susceptibility Gouveia, MH; Otim, I; Ogwang, MD et al. Leukemia, DOI://10.1038/s41375-021-01140-5 (2021)
- Regional Differences in Human Biliary Tissues and Corresponding In Vitro-Derived Organoids Rimland, CA; Tilson, SG; Morell, CM et al. Hepatology, DOI://10.1002/hep.31252 (2021)
- Correction to: Clinical Manifestations, Mutational Analysis, and Immunological Phenotype in Patients with RAG1/2 Mutations: First Cases Series from Mexico and Description of Two Novel Mutations Lugo-Reyes, SO; Pastor, N; González-Serrano, E et al. J Clin Immunol, DOI://10.1007/s10875-021-01075-7 (2021)
- Spreading and epigenetic inheritance of heterochromatin require a critical density of histone H3 lysine 9 tri-methylation Cutter DiPiazza, AR; Taneja, N; Dhakshnamoorthy, J et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2100699118 (2021)
- Clinical sites of the Undiagnosed Diseases Network: unique contributions to genomic medicine and science Schoch, K; Esteves, C; Bican, A et al. Genet Med, DOI://10.1038/s41436-020-00984-z (2021)
- A non-radioactive, improved PAR-CLIP and small RNA cDNA library preparation protocol Anastasakis, DG; Jacob, A; Konstantinidou, P et al. Nucleic Acids Res, DOI://10.1093/nar/gkab011 (2021)
- Dynamic imaging of nascent RNA reveals general principles of transcription dynamics and stochastic splice site selection Wan, Y; Anastasakis, DG; Rodriguez, J et al. Cell, DOI://10.1016/j.cell.2021.04.012 (2021)
- LRRC15 antibody-drug conjugates show promise as osteosarcoma therapeutics in preclinical studies Slemmons, KK; Mukherjee, S; Meltzer, P et al. Pediatr Blood Cancer, DOI://10.1002/pbc.28771 (2021)
- JAK inhibitors dampen activation of interferon-stimulated transcription of ACE2 isoforms in human airway epithelial cells Lee, HK; Jung, O; Hennighausen, L; , Commun Biol, DOI://10.1038/s42003-021-02167-1 (2021)
- Neuronal enhancers are hotspots for DNA single-strand break repair Wu, W; Hill, SE; Nathan, WJ et al. Nature, DOI://10.1038/s41586-021-03468-5 (2021)
- Profiling single-cell histone modifications using indexing chromatin immunocleavage sequencing Ku, WL; Pan, L; Cao, Y et al. Genome Res, DOI://10.1101/gr.260893.120 (2021)
- Human oral mucosa cell atlas reveals a stromal-neutrophil axis regulating tissue immunity Williams, DW; Greenwell-Wild, T; Brenchley, L et al. Cell, DOI://10.1016/j.cell.2021.05.013 (2021)
- Innate immune cells in the tumor microenvironment Li, MO; Wolf, N; Raulet, DH et al. Cancer Cell, DOI://10.1016/j.ccell.2021.05.016 (2021)
- Rare Germline Variants in Chordoma-Related Genes and Chordoma Susceptibility Yepes, S; Shah, NN; Bai, J et al. Cancers (Basel), DOI://10.3390/cancers13112704 (2021)
- Biomolecular interactions of ultrasmall metallic nanoparticles and nanoclusters Sousa, AA; Schuck, P; Hassan, SA; , Nanoscale Adv, DOI://10.1039/d1na00086a (2021)
- A complement factor H homolog, heparan sulfation, and syndecan maintain inversin compartment boundaries in C. elegans cilia Acker, N; Smith, H; Devine, C et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2016698118 (2021)
- The mechanism of full activation of tumor suppressor PTEN at the phosphoinositide-enriched membrane Jang, H; Smith, IN; Eng, C; Nussinov, R; , iScience, DOI://10.1016/j.isci.2021.102438 (2021)
- The mechanistic analysis of founder virus data in challenge models Ortega-Villa, AM; Nason, MC; Follmann, D; , Stat Med, DOI://10.1002/sim.9075 (2021)
- Functional and Regulatory Roles of Fold-Switching Proteins Kim, AK; Porter, LL; , Structure, DOI://10.1016/j.str.2020.10.006 (2021)
- An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids Ferdinandusse, S; McWalter, K; Te Brinke, H et al. Genet Med, DOI://10.1038/s41436-020-01027-3 (2021)
- Identification and Validation of Nutrient State-Dependent Serum Protein Mediators of Human CD4 + T Cell Responsiveness Han, K; Singh, K; Rodman, MJ et al. Nutrients, DOI://10.3390/nu13051492 (2021)
- Pathogenic Germline Variants in Cancer Susceptibility Genes in Children and Young Adults With Rhabdomyosarcoma Kim, J; Light, N; Subasri, V et al. JCO Precis Oncol, DOI://10.1200/PO.20.00218 (2021)
- Time-Varying Functional Connectivity Decreases as a Function of Acute Nicotine Abstinence Fedota, JR; Ross, TJ; Castillo, J et al. Biol Psychiatry Cogn Neurosci Neuroimaging, DOI://10.1016/j.bpsc.2020.10.004 (2021)
- Topological polymorphism of nucleosome fibers and folding of chromatin Zhurkin, VB; Norouzi, D; , Biophys J, DOI://10.1016/j.bpj.2021.01.008 (2021)
- A transcriptionally distinct subpopulation of healthy acinar cells exhibit features of pancreatic progenitors and pancreatic ductal adenocarcinoma Gopalan, V; Singh, A; Rashidi Mehrabadi, F et al. Cancer Res, DOI://10.1158/0008-5472.CAN-21-0427 (2021)
- Prefrontal Responses during Proactive and Reactive Inhibition Are Differentially Impacted by Stress in Anorexia and Bulimia Nervosa Westwater, ML; Mancini, F; Gorka, AX et al. J Neurosci, DOI://10.1523/JNEUROSCI.2853-20.2021 (2021)
- NLRP3 Inhibition Ameliorates Severe Cutaneous Autoimmune Manifestations in a Mouse Model of Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy-Like Disease Zhu, F; Willette-Brown, J; Zhang, J et al. J Invest Dermatol, DOI://10.1016/j.jid.2020.10.016 (2021)
- AniProtDB: A Collection of Consistently Generated Metazoan Proteomes for Comparative Genomics Studies Barreira, SN; Nguyen, AD; Fredriksen, MT et al. Mol Biol Evol, DOI://10.1093/molbev/msab165 (2021)
- Cutaneous T-Cell Lymphoma Skin Microbiome Is Characterized by Shifts in Certain Commensal Bacteria but not Viruses when Compared with Healthy Controls Harkins, CP; MacGibeny, MA; Thompson, K et al. J Invest Dermatol, DOI://10.1016/j.jid.2020.10.021 (2021)
- Impact of Conditioning Intensity and Genomics on Relapse After Allogeneic Transplantation for Patients With Myelodysplastic Syndrome Dillon, LW; Gui, G; Logan, BR et al. JCO Precis Oncol, DOI://10.1200/PO.20.00355 (2021)
- Gut microbiota composition is associated with newborn functional brain connectivity and behavioral temperament Kelsey, CM; Prescott, S; McCulloch, JA et al. Brain Behav Immun, DOI://10.1016/j.bbi.2020.11.003 (2021)
- Automated picking of amyloid fibrils from cryo-EM images for helical reconstruction with RELION Thurber, KR; Yin, Y; Tycko, R; , J Struct Biol, DOI://10.1016/j.jsb.2021.107736 (2021)
- Comparative Transcriptomic Analysis of the Hematopoietic System between Human and Mouse by Single Cell RNA Sequencing Gao, S; Wu, Z; Kannan, J et al. Cells, DOI://10.3390/cells10050973 (2021)
- Recurrent lymphadenitis in a female XIAP/BIRC4 mutation carrier with normal lyonization Durkee-Shock, JR; Kuehn, HS; Stoddard, J et al. J Allergy Clin Immunol Pract, DOI://10.1016/j.jaip.2020.10.062 (2021)
- MED1 is a lipogenesis coactivator required for postnatal adipose expansion Jang, Y; Park, YK; Lee, JE et al. Genes Dev, DOI://10.1101/gad.347583.120 (2021)
- Radiation-related genomic profile of papillary thyroid carcinoma after the Chernobyl accident Morton, LM; Karyadi, DM; Stewart, C et al. Science, DOI://10.1126/science.abg2538 (2021)
- A replica exchange umbrella sampling (REUS) approach to predict host-guest binding free energies in SAMPL8 challenge Ghorbani, M; Hudson, PS; Jones, MR et al. J Comput Aided Mol Des, DOI://10.1007/s10822-021-00385-7 (2021)
- A Data-Driven Hydrophobicity Scale for Predicting Liquid-Liquid Phase Separation of Proteins Dannenhoffer-Lafage, T; Best, RB; , J Phys Chem B, DOI://10.1021/acs.jpcb.0c11479 (2021)
- Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis Su, H; Yang, F; Fu, R et al. Cancer Cell, DOI://10.1016/j.ccell.2021.02.016 (2021)
- Bridged parametric survival models: General paradigm and speed improvements Swihart, BJ; Bandyopadhyay, D; , Comput Methods Programs Biomed, DOI://10.1016/j.cmpb.2021.106115 (2021)
- Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist Glassman, CR; Su, L; Majri-Morrison, SS et al. Elife, DOI://10.7554/eLife.65777 (2021)
- Lack of transgenerational effects of ionizing radiation exposure from the Chernobyl accident Yeager, M; Machiela, MJ; Kothiyal, P et al. Science, DOI://10.1126/science.abg2365 (2021)
- A miR-375/YAP axis regulates neuroendocrine differentiation and tumorigenesis in lung carcinoid cells Yang, X; Nanayakkara, J; Claypool, D et al. Sci Rep, DOI://10.1038/s41598-021-89855-4 (2021)
- COVID-19-CT-CXR: A Freely Accessible and Weakly Labeled Chest X-Ray and CT Image Collection on COVID-19 From Biomedical Literature Peng, Y; Tang, Y; Lee, S et al. IEEE Trans Big Data, DOI://10.1109/tbdata.2020.3035935 (2021)
- Severity modeling of propionic acidemia using clinical and laboratory biomarkers Shchelochkov, OA; Manoli, I; Juneau, P et al. Genet Med, DOI://10.1038/s41436-021-01173-2 (2021)
- Common Variable Immunodeficiency, Autoimmune Hemolytic Anemia, and Pancytopenia Associated With a Defect in IKAROS Yilmaz, E; Kuehn, HS; Odakir, E et al. J Pediatr Hematol Oncol, DOI://10.1097/MPH.0000000000001976 (2021)
- Cell-free DNA maps COVID-19 tissue injury and risk of death and can cause tissue injury Andargie, TE; Tsuji, N; Seifuddin, F et al. JCI Insight, DOI://10.1172/jci.insight.147610 (2021)
- Small RNAs are modified with N-glycans and displayed on the surface of living cells Flynn, RA; Pedram, K; Malaker, SA et al. Cell, DOI://10.1016/j.cell.2021.04.023 (2021)
- Genome-Wide Association Study Meta-Analysis for Parkinson Disease Motor Subtypes Alfradique-Dunham, I; Al-Ouran, R; von Coelln, R et al. Neurol Genet, DOI://10.1212/NXG.0000000000000557 (2021)
- Feeding-induced resistance to acute lethal sepsis is dependent on hepatic BMAL1 and FXR signalling Geiger, SS; Traba, J; Richoz, N et al. Nat Commun, DOI://10.1038/s41467-021-22961-z (2021)
- Membrane transporter dimerization driven by differential lipid solvation energetics of dissociated and associated states Chadda, R; Bernhardt, N; Kelley, EG et al. Elife, DOI://10.7554/eLife.63288 (2021)
- Next generation sequencing for HLA loci in full heritage Pima Indians of Arizona, Part II: HLA-A, -B, and -C with selected non-classical loci at 4-field resolution from whole genome sequences Williams, RC; Koroglu, C; Knowler, WC et al. Hum Immunol, DOI://10.1016/j.humimm.2021.03.013 (2021)
- Novel Murine Biomarkers of Radiation Exposure Using An Aptamer-Based Proteomic Technology Sproull, M; Shankavaram, U; Camphausen, K; , Front Pharmacol, DOI://10.3389/fphar.2021.633131 (2021)
- SeqEnhDL: sequence-based classification of cell type-specific enhancers using deep learning models Wang, Y; Jaime-Lara, RB; Roy, A et al. BMC Res Notes, DOI://10.1186/s13104-021-05518-7 (2021)
- Single nucleus RNA-sequencing defines unexpected diversity of cholinergic neuron types in the adult mouse spinal cord Alkaslasi, MR; Piccus, ZE; Hareendran, S et al. Nat Commun, DOI://10.1038/s41467-021-22691-2 (2021)
- Rapid Identification and Evaluation of Neoantigen-reactive T-Cell Receptors From Single Cells Paria, BC; Levin, N; Lowery, FJ et al. J Immunother, DOI://10.1097/CJI.0000000000000342 (2021)
- The Extended Eighth-Shell method for periodic boundary conditions with rotational symmetry Prasad, S; Simmonett, AC; Meana-Pañeda, R; Brooks, BR; , J Comput Chem, DOI://10.1002/jcc.26545 (2021)
- Germline IKAROS dimerization haploinsufficiency causes hematologic cytopenias and malignancies Kuehn, HS; Niemela, JE; Stoddard, J et al. Blood, DOI://10.1182/blood.2020007292 (2021)
- The ribosome modulates folding inside the ribosomal exit tunnel Wruck, F; Tian, P; Kudva, R et al. Commun Biol, DOI://10.1038/s42003-021-02055-8 (2021)
- Multimodal Functional Imaging for Cancer/Tumor Microenvironments Based on MRI, EPRI, and PET Matsumoto, KI; Mitchell, JB; Krishna, MC; , Molecules, DOI://10.3390/molecules26061614 (2021)
- Author Correction: High-depth African genomes inform human migration and health Choudhury, A; Aron, S; Botigué, LR et al. Nature, DOI://10.1038/s41586-021-03286-9 (2021)
- VPS13D promotes peroxisome biogenesis Baldwin, HA; Wang, C; Kanfer, G et al. J Cell Biol, DOI://10.1083/jcb.202001188 (2021)
- The causes of Fanconi anemia in South Asia and the Middle East: A case series and review of the literature Thompson, AS; Saba, N; McReynolds, LJ et al. Mol Genet Genomic Med, DOI://10.1002/mgg3.1693 (2021)
- Towards complete and error-free genome assemblies of all vertebrate species Rhie, A; McCarthy, SA; Fedrigo, O et al. Nature, DOI://10.1038/s41586-021-03451-0 (2021)
- Loss of DLX3 tumor suppressive function promotes progression of SCC through EGFR-ERBB2 pathway Bajpai, D; Mehdizadeh, S; Uchiyama, A et al. Oncogene, DOI://10.1038/s41388-021-01802-9 (2021)
- Social Heterogeneity Drives Complex Patterns of the COVID-19 Pandemic: Insights From a Novel Stochastic Heterogeneous Epidemic Model (SHEM) Alexander V. Maltsev & Michael D. Stern* Front. Phys., doi://10.3389/fphy.2020.609224 (2021)
- Human Histone Interaction Networks: An Old Concept, New Trends Peng, Y; Markov, Y; Goncearenco, A et al. J Mol Biol, DOI://10.1016/j.jmb.2020.10.018 (2021)
- Redundant and non-redundant cytokine-activated enhancers control Csn1s2b expression in the lactating mouse mammary gland Lee, HK; Willi, M; Kuhns, T et al. Nat Commun, DOI://10.1038/s41467-021-22500-w (2021)
- FIB-SEM as a Volume Electron Microscopy Approach to Study Cellular Architectures in SARS-CoV-2 and Other Viral Infections: A Practical Primer for a Virologist Baena, V; Conrad, R; Friday, P et al. Viruses, doi://10.3390/v13040611 (2021)
- Perfluorooctanoic acid (PFOA) or perfluorooctane sulfonate (PFOS) and DNA methylation in newborn dried blood spots in the Upstate KIDS cohort Robinson, SL; Zeng, X; Guan, W et al. Environ Res, DOI://10.1016/j.envres.2020.110668 (2021)
- TOR targets an RNA processing network to regulate facultative heterochromatin, developmental gene expression and cell proliferation Wei, Y; Lee, NN; Pan, L et al. Nat Cell Biol, DOI://10.1038/s41556-021-00631-y (2021)
- Threat-anticipatory psychophysiological response is enhanced in youth with anxiety disorders and correlates with prefrontal cortex neuroanatomy Abend, R; Bajaj, MA; Harrewijn, A et al. J Psychiatry Neurosci, DOI://10.1503/jpn.200110 (2021)
- Shared and Anxiety-Specific Pediatric Psychopathology Dimensions Manifest Distributed Neural Correlates Linke, JO; Abend, R; Kircanski, K et al. Biol Psychiatry, DOI://10.1016/j.biopsych.2020.10.018 (2021)
- Overexpression of Human ABCB1 and ABCG2 Reduces the Susceptibility of Cancer Cells to the Histone Deacetylase 6-Specific Inhibitor Citarinostat Wu, CP; Hung, CY; Lusvarghi, S et al. Int J Mol Sci, DOI://10.3390/ijms22052592 (2021)
- Host-Pathogen Interactions in Human Polyomavirus 7‒Associated Pruritic Skin Eruption Rosenstein, RK; Pastrana, DV; Starrett, GJ et al. J Invest Dermatol, DOI://10.1016/j.jid.2020.09.014 (2021)
- Morphological integration of the human brain across adolescence and adulthood Nadig, A; Seidlitz, J; McDermott, CL et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2023860118 (2021)
- SASH3 variants cause a novel form of X-linked combined immunodeficiency with immune dysregulation Delmonte, OM; Bergerson, JRE; Kawai, T et al. Blood, DOI://10.1182/blood.2020008629 (2021)
- Assessment of ANG variants in Parkinson's disease Grenn, FP; Moore, A; Bandres-Ciga, S et al. Neurobiol Aging, DOI://10.1016/j.neurobiolaging.2021.03.006 (2021)
- Ketamine Alters Electrophysiological Responses to Emotional Faces in Major Depressive Disorder Lundin, NB; Sepe-Forrest, L; Gilbert, JR et al. J Affect Disord, DOI://10.1016/j.jad.2020.10.007 (2021)
- Beam image-shift accelerated data acquisition for near-atomic resolution single-particle cryo-electron tomography Bouvette, J; Liu, HF; Du, X et al. Nat Commun, DOI://10.1038/s41467-021-22251-8 (2021)
- Skeletal muscle transcriptome in healthy aging Tumasian, RA; Harish, A; Kundu, G et al. Nat Commun, DOI://10.1038/s41467-021-22168-2 (2021)
- The structure, function and evolution of a complete human chromosome 8 Logsdon, GA; Vollger, MR; Hsieh, P et al. Nature, DOI://10.1038/s41586-021-03420-7 (2021)
- Synchronous RNA conformational changes trigger ordered phase transitions in crystals Ramakrishnan, S; Stagno, JR; Conrad, CE et al. Nat Commun, DOI://10.1038/s41467-021-21838-5 (2021)
- A comprehensive macaque fMRI pipeline and hierarchical atlas Jung, B; Taylor, PA; Seidlitz, J et al. Neuroimage, DOI://10.1016/j.neuroimage.2021.117997 (2021)
- Reprogramming of translation in yeast cells impaired for ribosome recycling favors short, efficiently translated mRNAs Gaikwad, S; Ghobakhlou, F; Young, DJ et al. Elife, DOI://10.7554/eLife.64283 (2021)
- Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress Thomas, A; Takahashi, N; Rajapakse, VN et al. Cancer Cell, DOI://10.1016/j.ccell.2021.02.014 (2021)
- Synthetic lethality-mediated precision oncology via the tumor transcriptome Lee, JS; Nair, NU; Dinstag, G et al. Cell, DOI://10.1016/j.cell.2021.03.030 (2021)
- SomatoSim: precision simulation of somatic single nucleotide variants Hawari, MA; Hong, CS; Biesecker, LG; , BMC Bioinformatics, DOI://10.1186/s12859-021-04024-8 (2021)
- Functional Anatomy of the Trimer Apex Reveals Key Hydrophobic Constraints That Maintain the HIV-1 Envelope Spike in a Closed State Zhang, P; Kwon, AL; Guzzo, C et al. mBio, DOI://10.1128/mBio.00090-21 (2021)
- Beyond linearity in neuroimaging: Capturing nonlinear relationships with application to longitudinal studies Chen, G; Nash, TA; Cole, KM et al. Neuroimage, DOI://10.1016/j.neuroimage.2021.117891 (2021)
- CEM500K, a large-scale heterogeneous unlabeled cellular electron microscopy image dataset for deep learning Conrad, R; Narayan, K; Elife, DOI://10.7554/eLife.65894 (2021)
- Martini 3: a general purpose force field for coarse-grained molecular dynamics Souza, PCT; Alessandri, R; Barnoud, J et al. Nat Methods, DOI://10.1038/s41592-021-01098-3 (2021)
- SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation Yan, B; Freiwald, T; Chauss, D et al. Sci Immunol, DOI://10.1126/sciimmunol.abg0833 (2021)
- A transcription-centric model of SNP-age interaction Wang, K; Basu, M; Malin, J; Hannenhalli, S; , PLoS Genet, DOI://10.1371/journal.pgen.1009427 (2021)
- Conception by fertility treatment and offspring deoxyribonucleic acid methylation Yeung, EH; Mendola, P; Sundaram, R et al. Fertil Steril, DOI://10.1016/j.fertnstert.2021.03.011 (2021)
- Network Analysis and Transcriptome Profiling Identify Autophagic and Mitochondrial Dysfunctions in SARS-CoV-2 Infection Singh, K; Chen, YC; Hassanzadeh, S et al. Front Genet, DOI://10.3389/fgene.2021.599261 (2021)
- Genome-wide binding potential and regulatory activity of the glucocorticoid receptor's monomeric and dimeric forms Johnson, TA; Paakinaho, V; Kim, S; Hager, GL; Presman, DM; , Nat Commun, DOI://10.1038/s41467-021-22234-9 (2021)
- Predicting tissue-specific gene expression from whole blood transcriptome Basu, M; Wang, K; Ruppin, E; Hannenhalli, S; , Sci Adv, DOI://10.1126/sciadv.abd6991 (2021)
- Movie-watching outperforms rest for functional connectivity-based prediction of behavior Finn, ES; Bandettini, PA; , Neuroimage, DOI://10.1016/j.neuroimage.2021.117963 (2021)
- Interplay of BAF and MLL4 promotes cell type-specific enhancer activation Park, YK; Lee, JE; Yan, Z et al. Nat Commun, DOI://10.1038/s41467-021-21893-y (2021)
- Structure-Activity Relationship of Heterocyclic P2Y 14 Receptor Antagonists: Removal of the Zwitterionic Character with Piperidine Bioisosteres Jung, YH; Salmaso, V; Wen, Z et al. J Med Chem, DOI://10.1021/acs.jmedchem.1c00164 (2021)
- Nascent Prostate Cancer Heterogeneity Drives Evolution and Resistance to Intense Hormonal Therapy Wilkinson, S; Ye, H; Karzai, F et al. Eur Urol, DOI://10.1016/j.eururo.2021.03.009 (2021)
- Thousands of previously unknown phages discovered in whole-community human gut metagenomes Benler, S; Yutin, N; Antipov, D et al. Microbiome, DOI://10.1186/s40168-021-01017-w (2021)
- Genomic insights into the host specific adaptation of the Pneumocystis genus Cissé, OH; Ma, L; Dekker, JP et al. Commun Biol, DOI://10.1038/s42003-021-01799-7 (2021)
- New insights into modeling exposure measurements below the limit of detection Ortega-Villa, AM; Liu, D; Ward, MH; Albert, PS; , Environ Epidemiol, DOI://10.1097/EE9.0000000000000116 (2021)
- The Structural Basis of Akt PH Domain Interaction with Calmodulin Weako, J; Jang, H; Keskin, O; Nussinov, R; Gursoy, A; , Biophys J, DOI://10.1016/j.bpj.2021.03.018 (2021)
- The NIMH Intramural Longitudinal Study of the Endocrine and Neurobiological Events Accompanying Puberty: Protocol and Rationale for Methods and Measures Cole, KM; Wei, SM; Martinez, PE et al. Neuroimage, DOI://10.1016/j.neuroimage.2021.117970 (2021)
- Performance in even a simple perceptual task depends on mouse secondary visual areas Goldbach, HC; Akitake, B; Leedy, CE; Histed, MH; , Elife, DOI://10.7554/eLife.62156 (2021)
- Estimating transition path times and shapes from single-molecule photon trajectories: A simulation analysis Taumoefolau, GH; Best, RB; , J Chem Phys, DOI://10.1063/5.0040949 (2021)
- SARS-CoV-2 infection of the oral cavity and saliva Huang, N; Pérez, P; Kato, T et al. Nat Med, DOI://10.1038/s41591-021-01296-8 (2021)
- A Comprehensive Map of mRNAs and Their Isoforms across All 14 Renal Tubule Segments of Mouse Chen, L; Chou, CL; Knepper, MA; , J Am Soc Nephrol, DOI://10.1681/ASN.2020101406 (2021)
- Integrative analysis of multiple case-control studies Zhang, H; Deng, L; Wheeler, W; Qin, J; Yu, K; , Biometrics, DOI://10.1111/biom.13461 (2021)
- Epigenome-wide association study of whole blood gene expression in Framingham Heart Study participants provides molecular insight into the potential role of CHRNA5 in cigarette smoking-related lung diseases Yao, C; Joehanes, R; Wilson, R et al. Clin Epigenetics, DOI://10.1186/s13148-021-01041-5 (2021)
- Genetically engineered myeloid cells rebalance the core immune suppression program in metastasis Kaczanowska, S; Beury, DW; Gopalan, V et al. Cell, DOI://10.1016/j.cell.2021.02.048 (2021)
- Exploring dynamics and network analysis of spike glycoprotein of SARS-COV-2 Ghorbani, M; Brooks, BR; Klauda, JB; , Biophys J, DOI://10.1016/j.bpj.2021.02.047 (2021)
- Genomic diversity of SARS-CoV-2 during early introduction into the Baltimore-Washington metropolitan area Thielen, PM; Wohl, S; Mehoke, T et al. JCI Insight, DOI://10.1172/jci.insight.144350 (2021)
- Conformational Ensemble of Tte AdoCbl Riboswitch Provides Stable Structural Elements for Conformation Selection and Population Shift in Cobalamin Recognition Ma, B; Bai, G; Nussinov, R; Ding, J; Wang, YX; , J Phys Chem B, DOI://10.1021/acs.jpcb.1c00038 (2021)
- Targeting natural splicing plasticity of APOBEC3B restricts its expression and mutagenic activity Rouf Banday, A; Onabajo, OO; Lin, SH et al. Commun Biol, DOI://10.1038/s42003-021-01844-5 (2021)
- Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation Guan, R; Lian, T; Zhou, BR et al. Nat Commun, DOI://10.1038/s41467-021-21985-9 (2021)
- Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma Hung, MH; Lee, JS; Ma, C et al. Nat Commun, DOI://10.1038/s41467-021-21804-1 (2021)
- Iterative epigenomic analyses in the same single cell Ohnuki, H; Venzon, DJ; Lobanov, A; Tosato, G; , Genome Res, DOI://10.1101/gr.269068.120 (2021)
- Correction to: The Haskins pediatric atlas: a magnetic-resonance-imaging-based pediatric template and atlas Molfese, PJ; Glen, D; Mesite, L et al. Pediatr Radiol, DOI://10.1007/s00247-020-04958-w (2021)
- Ancestral haplotype reconstruction in endogamous populations using identity-by-descent Finke, K; Kourakos, M; Brown, G et al. PLoS Comput Biol, DOI://10.1371/journal.pcbi.1008638 (2021)
- Chloride-dependent conformational changes in the GlyT1 glycine transporter Zhang, YW; Uchendu, S; Leone, V et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2017431118 (2021)
- Death agonist antibody against TRAILR2/DR5/TNFRSF10B enhances birinapant anti-tumor activity in HPV-positive head and neck squamous cell carcinomas An, Y; Jeon, J; Sun, L et al. Sci Rep, DOI://10.1038/s41598-021-85589-5 (2021)
- Structure of membrane diacylglycerol kinase in lipid bilayers Li, J; Shen, Y; Chen, Y et al. Commun Biol, DOI://10.1038/s42003-021-01802-1 (2021)
- Comparative engraftment and clonality of macaque HSPCs expanded on human umbilical vein endothelial cells versus non-expanded cells Srivastava, SK; Truitt, LL; Wu, C et al. Mol Ther Methods Clin Dev, DOI://10.1016/j.omtm.2021.02.009 (2021)
- Genetically inferred telomere length and testicular germ cell tumor risk Brown, DW; Lan, Q; Rothman, N et al. Cancer Epidemiol Biomarkers Prev, DOI://10.1158/1055-9965.EPI-20-1775 (2021)
- Nascent RNA sequencing identifies a widespread sigma70-dependent pausing regulated by Gre factors in bacteria Sun, Z; Yakhnin, AV; FitzGerald, PC et al. Nat Commun, DOI://10.1038/s41467-021-21150-2 (2021)
- Tumor IsomiR Encyclopedia (TIE): a pancancer database of miRNA isoforms Bofill-De Ros, X; Luke, B; Guthridge, R et al. Bioinformatics, DOI://10.1093/bioinformatics/btab172 (2021)
- Fully automated CT imaging biomarkers of bone, muscle, and fat: correcting for the effect of intravenous contrast Perez, AA; Pickhardt, PJ; Elton, DC; Sandfort, V; Summers, RM; , Abdom Radiol (NY), DOI://10.1007/s00261-020-02755-5 (2021)
- Retroviral Elements in Human Evolution and Neural Development Wang, T; Doucet-O'Hare, TT; Henderson, L et al. J Exp Neurol, 2692-2819 (2021)
- B-Raf autoinhibition in the presence and absence of 14-3-3 Zhang, M; Jang, H; Li, Z; Sacks, DB; Nussinov, R; , Structure, DOI://10.1016/j.str.2021.02.005 (2021)
- Single-Cell RNA Sequencing Analysis of the Drosophila Larval Ventral Cord Nguyen, TH; Vicidomini, R; Choudhury, SD et al. Curr Protoc, DOI://10.1002/cpz1.38 (2021)
- Dose conversion coefficients for neutron external exposures with five postures: walking, sitting, bending, kneeling, and squatting Yeom, YS; Griffin, K; Han, H et al. Radiat Environ Biophys, DOI://10.1007/s00411-021-00900-2 (2021)
- Multiplex indexing approach for the detection of DNase I hypersensitive sites in single cells Gao, W; Ku, WL; Pan, L et al. Nucleic Acids Res, DOI://10.1093/nar/gkab102 (2021)
- MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23 Mikami, Y; Philips, RL; Sciumè, G et al. Immunity, DOI://10.1016/j.immuni.2021.02.015 (2021)
- Mitochondrial Ca 2+, redox environment and ROS emission in heart failure: Two sides of the same coin? Cortassa, S; Juhaszova, M; Aon, MA et al. J Mol Cell Cardiol, DOI://10.1016/j.yjmcc.2020.11.013 (2021)
- CHARMM36 Lipid Force Field with Explicit Treatment of Long-Range Dispersion: Parametrization and Validation for Phosphatidylethanolamine, Phosphatidylglycerol, and Ether Lipids Yu, Y; Krämer, A; Venable, RM et al. J Chem Theory Comput, DOI://10.1021/acs.jctc.0c01327 (2021)
- Semi-automated Optimization of the CHARMM36 Lipid Force Field to Include Explicit Treatment of Long-Range Dispersion Yu, Y; Krämer, A; Venable, RM et al. J Chem Theory Comput, DOI://10.1021/acs.jctc.0c01326 (2021)
- Midbrain activity shapes high-level visual properties in the primate temporal cortex Bogadhi, AR; Katz, LN; Bollimunta, A et al. Neuron, DOI://10.1016/j.neuron.2020.11.023 (2021)
- Loop extrusion mediates physiological Igh locus contraction for RAG scanning Dai, HQ; Hu, H; Lou, J et al. Nature, DOI://10.1038/s41586-020-03121-7 (2021)
- Mechanism of membrane-tethered mitochondrial protein synthesis Itoh, Y; Andréll, J; Choi, A et al. Science, DOI://10.1126/science.abe0763 (2021)
- Gene-based analysis of bi-variate survival traits via functional regressions with applications to eye diseases Zhang, B; Chiu, CY; Yuan, F et al. Genet Epidemiol, DOI://10.1002/gepi.22381 (2021)
- BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8 + T cells Yao, C; Lou, G; Sun, HW et al. Nat Immunol, DOI://10.1038/s41590-021-00868-7 (2021)
- Lysosome-associated membrane protein 3 misexpression in salivary glands induces a Sjögren's syndrome-like phenotype in mice Nakamura, H; Tanaka, T; Pranzatelli, T et al. Ann Rheum Dis, DOI://10.1136/annrheumdis-2020-219649 (2021)
- Structure of an activated DNA-PK and its implications for NHEJ Chen, X; Xu, X; Chen, Y et al. Mol Cell, DOI://10.1016/j.molcel.2020.12.015 (2021)
- Does the ATP-bound EQ mutant reflect the pre- or post-ATP hydrolysis state in the catalytic cycle of human P-glycoprotein (ABCB1)? Lusvarghi, S; Durell, SR; Ambudkar, SV; , FEBS Lett, DOI://10.1002/1873-3468.14054 (2021)
- Audiovisual integration in macaque face patch neurons Khandhadia, AP; Murphy, AP; Romanski, LM; Bizley, JK; Leopold, DA; , Curr Biol, DOI://10.1016/j.cub.2021.01.102 (2021)
- A Genome-First Approach to Characterize DICER1 Pathogenic Variant Prevalence, Penetrance, and Phenotype Mirshahi, UL; Kim, J; Best, AF et al. JAMA Netw Open, DOI://10.1001/jamanetworkopen.2021.0112 (2021)
- The Myc-associated zinc finger protein (MAZ) works together with CTCF to control cohesin positioning and genome organization Xiao, T; Li, X; Felsenfeld, G; , Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2023127118 (2021)
- Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits Gouveia, MH; Bentley, AR; Leonard, H et al. Sci Rep, DOI://10.1038/s41598-021-83450-3 (2021)
- Deep-learning based multi-modal retinal image registration for the longitudinal analysis of patients with age-related macular degeneration De Silva, T; Chew, EY; Hotaling, N; Cukras, CA; , Biomed Opt Express, DOI://10.1364/BOE.408573 (2021)
- TRF2-mediated telomere protection is dispensable in pluripotent stem cells Markiewicz-Potoczny, M; Lobanova, A; Loeb, AM et al. Nature, DOI://10.1038/s41586-020-2959-4 (2021)
- The yeast ISW1b ATP-dependent chromatin remodeler is critical for nucleosome spacing and dinucleosome resolution Eriksson, PR; Clark, DJ; , Sci Rep, DOI://10.1038/s41598-021-82842-9 (2021)
- Smoking modifies pancreatic cancer risk loci on 2q21.3 Mocci, E; Kundu, P; Wheeler, W et al. Cancer Res, DOI://10.1158/0008-5472.CAN-20-3267 (2021)
- Whole genome sequencing of skull-base chordoma reveals genomic alterations associated with recurrence and chordoma-specific survival Bai, J; Shi, J; Li, C et al. Nat Commun, DOI://10.1038/s41467-021-21026-5 (2021)
- Exome Sequencing of 21 Bardet-Biedl Syndrome (BBS) Genes to Identify Obesity Variants in 6,851 American Indians Day, SE; Muller, YL; Koroglu, C et al. Obesity (Silver Spring), DOI://10.1002/oby.23115 (2021)
- Immune transcriptomes of highly exposed SARS-CoV-2 asymptomatic seropositive versus seronegative individuals from the Ischgl community Lee, HK; Knabl, L; Pipperger, L et al. Sci Rep, DOI://10.1038/s41598-021-83110-6 (2021)
- The NF-κB regulator Bcl-3 restricts terminal differentiation and promotes memory cell formation of CD8+ T cells during viral infection Jaiswal, H; Ciucci, T; Wang, H et al. PLoS Pathog, DOI://10.1371/journal.ppat.1009249 (2021)
- Gene Therapy of Dominant CRX-Leber Congenital Amaurosis using Patient Stem Cell-Derived Retinal Organoids Kruczek, K; Qu, Z; Gentry, J et al. Stem Cell Reports, DOI://10.1016/j.stemcr.2020.12.018 (2021)
- Total Ortholog Median Matrix as an alternative unsupervised approach for phylogenomics based on evolutionary distance between protein coding genes Maruyama, SR; Rogerio, LA; Freitas, PD; Teixeira, MMG; Ribeiro, JMC; , Sci Rep, DOI://10.1038/s41598-021-81926-w (2021)
- Dynamic sex chromosome expression in Drosophila male germ cells Mahadevaraju, S; Fear, JM; Akeju, M et al. Nat Commun, DOI://10.1038/s41467-021-20897-y (2021)
- Admixture mapping identifies African and Amerindigenous local ancestry loci associated with fetal growth Tekola-Ayele, F; Ouidir, M; Shrestha, D et al. Hum Genet, DOI://10.1007/s00439-021-02265-4 (2021)
- Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture Chia, R; Sabir, MS; Bandres-Ciga, S et al. Nat Genet, DOI://10.1038/s41588-021-00785-3 (2021)
- Genome-wide transcriptome study using deep RNA sequencing for myocardial infarction and coronary artery calcification Zhang, X; van Rooij, JGJ; Wakabayashi, Y et al. BMC Med Genomics, DOI://10.1186/s12920-020-00838-2 (2021)
- Assessment of assumptions underlying models of prokaryotic pangenome evolution Sela, I; Wolf, YI; Koonin, EV; , BMC Biol, DOI://10.1186/s12915-021-00960-2 (2021)
- Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets Kia, DA; Zhang, D; Guelfi, S et al. JAMA Neurol, DOI://10.1001/jamaneurol.2020.5257 (2021)
- Molecular structure of a prevalent amyloid-β fibril polymorph from Alzheimer's disease brain tissue Ghosh, U; Thurber, KR; Yau, WM; Tycko, R; , Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2023089118 (2021)
- An open-source python library for detection of known and novel Kell, Duffy and Kidd variants from exome sequencing Montemayor, C; Simone, A; Long, J et al. Vox Sang, DOI://10.1111/vox.13035 (2021)
- On the Role of a Conserved Methionine in the Na+-Coupling Mechanism of a Neurotransmitter Transporter Homolog Zhou, W; Trinco, G; Slotboom, DJ; Forrest, LR; Faraldo-Gómez, JD; , Neurochem Res, DOI://10.1007/s11064-021-03253-w (2021)
- The genomic structure of a human chromosome 22 nucleolar organizer region determined by TAR cloning Kim, JH; Noskov, VN; Ogurtsov, AY et al. Sci Rep, DOI://10.1038/s41598-021-82565-x (2021)
- Deep transcriptome sequencing of subgenual anterior cingulate cortex reveals cross-diagnostic and diagnosis-specific RNA expression changes in major psychiatric disorders Akula, N; Marenco, S; Johnson, K et al. Neuropsychopharmacology, DOI://10.1038/s41386-020-00949-5 (2021)
- An examination of the relationships between attention/deficit hyperactivity disorder symptoms and functional connectivity over time Norman, LJ; Sudre, G; Bouyssi-Kobar, M; Sharp, W; Shaw, P; , Neuropsychopharmacology, DOI://10.1038/s41386-021-00958-y (2021)
- Trastuzumab Blocks the Receiver Function of HER2 Leading to the Population Shifts of HER2-Containing Homodimers and Heterodimers Zhao, J; Mohan, N; Nussinov, R; Ma, B; Wu, WJ; , Antibodies (Basel), DOI://10.3390/antib10010007 (2021)
- Infection trains the host for microbiota-enhanced resistance to pathogens Stacy, A; Andrade-Oliveira, V; McCulloch, JA et al. Cell, DOI://10.1016/j.cell.2020.12.011 (2021)
- Active and Inactive Cdc42 Differ in Their Insert Region Conformational Dynamics Haspel, N; Jang, H; Nussinov, R; , Biophys J, DOI://10.1016/j.bpj.2020.12.007 (2021)
- Linkage-specific deubiquitylation by OTUD5 defines an embryonic pathway intolerant to genomic variation Beck, DB; Basar, MA; Asmar, AJ et al. Sci Adv, DOI://10.1126/sciadv.abe2116 (2021)
- Synthetic lethality across normal tissues is strongly associated with cancer risk, onset, and tumor suppressor specificity Cheng, K; Nair, NU; Lee, JS; Ruppin, E; , Sci Adv, DOI://10.1126/sciadv.abc2100 (2021)
- Genetic analysis of amyotrophic lateral sclerosis identifies contributing pathways and cell types Saez-Atienzar, S; Bandres-Ciga, S; Langston, RG et al. Sci Adv, DOI://10.1126/sciadv.abd9036 (2021)
- Self-organizing maps with variable neighborhoods facilitate learning of chromatin accessibility signal shapes associated with regulatory elements Eicher, T; Chan, J; Luu, H; Machiraju, R; Mathé, EA; , BMC Bioinformatics, DOI://10.1186/s12859-021-03976-1 (2021)
- Associations of maternal blood pressure-raising polygenic risk scores with fetal weight Workalemahu, T; Rahman, ML; Ouidir, M; Wu, J; Zhang, C; Tekola-Ayele, F; , J Hum Hypertens, DOI://10.1038/s41371-021-00483-x (2021)
- Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics Pillon, MC; Frazier, MN; Dillard, LB et al. Nat Commun, DOI://10.1038/s41467-020-20608-z (2021)
- Dense cellular segmentation for EM using 2D-3D neural network ensembles Guay, MD; Emam, ZAS; Anderson, AB et al. Sci Rep, DOI://10.1038/s41598-021-81590-0 (2021)
- An optimized protocol for acquiring and processing cryo-EM data of human 26S proteasome with M1-Ub6 Chen, X; Shi, D; Zhang, P; Walters, KJ; , STAR Protoc, DOI://10.1016/j.xpro.2020.100278 (2021)
- A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication Hattori, SI; Higashi-Kuwata, N; Hayashi, H et al. Nat Commun, DOI://10.1038/s41467-021-20900-6 (2021)
- Whole-exome sequencing reveals germline-mutated small cell lung cancer subtype with favorable response to DNA repair-targeted therapies Tlemsani, C; Takahashi, N; Pongor, L et al. Sci Transl Med, DOI://10.1126/scitranslmed.abc7488 (2021)
- Cenote-Taker 2 democratizes virus discovery and sequence annotation Tisza, MJ; Belford, AK; Domínguez-Huerta, G; Bolduc, B; Buck, CB; , Virus Evol, DOI://10.1093/ve/veaa100 (2021)
- Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma Pomella, S; Sreenivas, P; Gryder, BE et al. Nat Commun, DOI://10.1038/s41467-020-20386-8 (2021)
- Glycolytic metabolism of pathogenic T cells enables early detection of GVHD by 13C-MRI Assmann, JC; Farthing, DE; Saito, K et al. Blood, DOI://10.1182/blood.2020005770 (2021)
- TCF7L2 silencing results in altered gene expression patterns accompanied by local genomic reorganization Brown, MA; Dotson, GA; Ronquist, S; Emons, G; Rajapakse, I; Ried, T; , Neoplasia, DOI://10.1016/j.neo.2020.12.010 (2021)
- Overexpression of the Bacteriophage T4 motB Gene Alters H-NS Dependent Repression of Specific Host DNA Patterson-West, J; Tai, CH; Son, B; Hsieh, ML; Iben, JR; Hinton, DM; , Viruses, DOI://10.3390/v13010084 (2021)
- Regulatory roles of Escherichia coli 5'UTR and ORF-internal RNAs detected by 3'end mapping Adams, PP; Baniulyte, G; Esnault, C et al. Elife, DOI://10.7554/eLife.62438 (2021)
- Survivin Expression is Differentially Regulated by a Selective Crosstalk between Rbm38 and miRNAs let-7b or miR-203a Lucchesi, CA; Zhang, J; Ma, B; Nussinov, R; Chen, X; , Cancer Res, DOI://10.1158/0008-5472.CAN-20-3157 (2021)
- Image-based pooled whole-genome CRISPRi screening for subcellular phenotypes Kanfer, G; Sarraf, SA; Maman, Y et al. J Cell Biol, DOI://10.1083/jcb.202006180 (2021)
- A Tumor Suppressor Enhancer of PTEN in T-cell development and leukemia Tottone, L; Lancho, O; Loh, JW et al. Blood Cancer Discov, DOI://10.1158/2643-3230.BCD-20-0201 (2021)
- A high-throughput predictive method for sequence-similar fold switchers Kim, AK; Looger, LL; Porter, LL; , Biopolymers, DOI://10.1002/bip.23416 (2021)
- Marmoset Brain Mapping V3: Population multi-modal standard volumetric and surface-based templates Liu, C; Yen, CC; Szczupak, D; Tian, X; Glen, D; Silva, AC; , Neuroimage, DOI://10.1016/j.neuroimage.2020.117620 (2021)
- A collaborative resource platform for non-human primate neuroimaging Messinger, A; Sirmpilatze, N; Heuer, K et al. Neuroimage, DOI://10.1016/j.neuroimage.2020.117519 (2021)
- Thymic stromal lymphopoietin limits primary and recall CD8 + T-cell anti-viral responses Ebina-Shibuya, R; West, EE; Spolski, R et al. Elife, DOI://10.7554/eLife.61912 (2021)
- Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet-induced diabetes Rodrigues, RR; Gurung, M; Li, Z et al. Nat Commun, DOI://10.1038/s41467-020-20313-x (2021)
- Ambulatory Assessment Methods to Examine Momentary State-Based Predictors of Opioid Use Behaviors Burgess-Hull, A; Epstein, DH; , Curr Addict Rep, DOI://10.1007/s40429-020-00351-7 (2021)
- Pleiotropic genetic influence on birth weight and childhood obesity Chatterjee, S; Ouidir, M; Tekola-Ayele, F; , Sci Rep, DOI://10.1038/s41598-020-80084-9 (2021)
- A population scale analysis of rare SNCA variation in the UK Biobank Blauwendraat, C; Makarious, MB; Leonard, HL et al. Neurobiol Dis, DOI://10.1016/j.nbd.2020.105182 (2021)
- Platypus and echidna genomes reveal mammalian biology and evolution Zhou, Y; Shearwin-Whyatt, L; Li, J et al. Nature, DOI://10.1038/s41586-020-03039-0 (2021)
- Conserved binding site in the N-lobe of prokaryotic MATE transporters suggests a role for Na + in ion-coupled drug efflux Castellano, S; Claxton, DP; Ficici, E et al. J Biol Chem, DOI://10.1074/jbc.RA120.016792 (2021)
- Malaria parasites use a soluble RhopH complex for erythrocyte invasion and an integral form for nutrient uptake Schureck, MA; Darling, JE; Merk, A et al. Elife, DOI://10.7554/eLife.65282 (2021)
- Automated assessment of longitudinal biomarker changes at abdominal CT: correlation with subsequent cardiovascular events in an asymptomatic adult screening cohort Graffy, PM; Summers, RM; Perez, AA; Sandfort, V; Zea, R; Pickhardt, PJ; , Abdom Radiol (NY), DOI://10.1007/s00261-020-02885-w (2021)
- Great Expectations: A Critical Review of and Suggestions for the Study of Reward Processing as a Cause and Predictor of Depression Nielson, DM; Keren, H; O'Callaghan, G et al. Biol Psychiatry, DOI://10.1016/j.biopsych.2020.06.012 (2021)
- END-seq: An Unbiased, High-Resolution, and Genome-Wide Approach to Map DNA Double-Strand Breaks and Resection in Human Cells Wong, N; John, S; Nussenzweig, A; Canela, A; , Methods Mol Biol, DOI://10.1007/978-1-0716-0644-5_2 (2021)
2020 (519 papers)
- Activation of the SARS-CoV-2 receptor Ace2 by cytokines through pan JAK-STAT enhancers Hennighausen, L; Lee, HK; , SSRN, DOI://10.2139/ssrn.3601827 (2020)
- Genomic profiling of primary histiocytic sarcoma reveals two molecular subgroups Egan, C; Nicolae, A; Lack, J et al. Haematologica, DOI://10.3324/haematol.2019.230375 (2020)
- Higher prevalence of homologous recombination deficiency in tumors from African Americans versus European Americans Sinha, S; Mitchell, KA; Zingone, A et al. Nat Cancer, DOI://10.1038/s43018-019-0009-7 (2020)
- Incorporation of α-methylated amino acids into Apolipoprotein A-I mimetic peptides improves their helicity and cholesterol efflux potential Islam, R; Sviridov, DO; Drake, SK et al. Biochem Biophys Res Commun, DOI://10.1016/j.bbrc.2020.03.070 (2020)
- Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivity Manzella, G; Schreck, LD; Breunis, WB et al. Nat Commun, DOI://10.1038/s41467-020-18388-7 (2020)
- Novel, abundant Drosha isoforms are deficient in miRNA processing in cancer cells Dai, L; Hallmark, L; Bofill De Ros, X et al. RNA Biol, DOI://10.1080/15476286.2020.1813439 (2020)
- Identification and functional validation of genetic variants in potential miRNA target sites of established BMI genes Kumar, P; Traurig, M; Baier, LJ; , Int J Obes (Lond), DOI://10.1038/s41366-019-0488-8 (2020)
- Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations Chen, MH; Raffield, LM; Mousas, A et al. Cell, DOI://10.1016/j.cell.2020.06.045 (2020)
- The genomic landscape of Mongolian hepatocellular carcinoma Candia, J; Bayarsaikhan, E; Tandon, M et al. Nat Commun, DOI://10.1038/s41467-020-18186-1 (2020)
- Author Correction: Mapping histone modifications in low cell number and single cells using antibody-guided chromatin tagmentation (ACT-seq) Carter, B; Ku, WL; Kang, JY et al. Nat Commun, DOI://10.1038/s41467-020-18309-8 (2020)
- The GENDULF algorithm: mining transcriptomics to uncover modifier genes for monogenic diseases Auslander, N; Ramos, DM; Zelaya, I et al. Mol Syst Biol, DOI://10.15252/msb.20209701 (2020)
- Exome Sequencing Identifies A Nonsense Variant in DAO Associated With Reduced Energy Expenditure in American Indians Piaggi, P; Köroğlu, Ç; Nair, AK et al. J Clin Endocrinol Metab, DOI://10.1210/clinem/dgaa548 (2020)
- Retinal ganglion cell defects cause decision shifts in visually evoked defense responses Lees, RN; Akbar, AF; Badea, TC; , J Neurophysiol, DOI://10.1152/jn.00474.2019 (2020)
- In vitro model of perimenopausal depression implicates steroid metabolic and proinflammatory genes Rudzinskas, S; Hoffman, JF; Martinez, P et al. Mol Psychiatry, DOI://10.1038/s41380-020-00860-x (2020)
- NusG-dependent RNA polymerase pausing is a frequent function of this universally conserved transcription elongation factor Yakhnin, AV; Kashlev, M; Babitzke, P; , Crit Rev Biochem Mol Biol, DOI://10.1080/10409238.2020.1828261 (2020)
- The Genetic Basis of Morphological Diversity in Domesticated Goldfish Kon, T; Omori, Y; Fukuta, K et al. Curr Biol, DOI://10.1016/j.cub.2020.04.034 (2020)
- Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma Brudno, JN; Lam, N; Vanasse, D et al. Nat Med, DOI://10.1038/s41591-019-0737-3 (2020)
- Genomic analyses of a livestock pest, the New World screwworm, find potential targets for genetic control programs Scott, MJ; Benoit, JB; Davis, RJ et al. Commun Biol, DOI://10.1038/s42003-020-01152-4 (2020)
- Transcriptome analysis of desmoplastic small round cell tumors identifies actionable therapeutic targets: a report from the Children's Oncology Group Hingorani, P; Dinu, V; Zhang, X et al. Sci Rep, DOI://10.1038/s41598-020-69015-w (2020)
- LSH mediates gene repression through macroH2A deposition Ni, K; Ren, J; Xu, X et al. Nat Commun, DOI://10.1038/s41467-020-19159-0 (2020)
- Improved reference genome of the arboviral vector Aedes albopictus Palatini, U; Masri, RA; Cosme, LV et al. Genome Biol, DOI://10.1186/s13059-020-02141-w (2020)
- Whole-Exome Profiling of NSCLC Among African Americans Arauz, RF; Byun, JS; Tandon, M et al. J Thorac Oncol, DOI://10.1016/j.jtho.2020.08.029 (2020)
- HLA tapasin independence: broader peptide repertoire and HIV control Bashirova, AA; Viard, M; Naranbhai, V et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2013554117 (2020)
- Disappearance of the polyelectrolyte peak in salt-free solutions Chremos, A; Horkay, F; , Phys Rev E, DOI://10.1103/PhysRevE.102.012611 (2020)
- Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease Beck, DB; Ferrada, MA; Sikora, KA et al. N Engl J Med, DOI://10.1056/NEJMoa2026834 (2020)
- Biallelic variants in two complex I genes cause abnormal splicing defects in probands with mild Leigh syndrome Johnstone, T; Wang, J; Ross, D et al. Mol Genet Metab, DOI://10.1016/j.ymgme.2020.09.008 (2020)
- Multilayer MEG functional connectivity as a potential marker for suicidal thoughts in major depressive disorder Nugent, AC; Ballard, ED; Gilbert, JR et al. Neuroimage Clin, DOI://10.1016/j.nicl.2020.102378 (2020)
- Development and validation of prognostic gene signature for basal-like breast cancer and high-grade serous ovarian cancer Zhang, Y; Liu, J; Raj-Kumar, PK et al. Breast Cancer Res Treat, DOI://10.1007/s10549-020-05884-z (2020)
- A Cutibacterium acnes antibiotic modulates human skin microbiota composition in hair follicles Claesen, J; Spagnolo, JB; Ramos, SF et al. Sci Transl Med, DOI://10.1126/scitranslmed.aay5445 (2020)
- Therapeutic responses to Roseomonas mucosa in atopic dermatitis may involve lipid-mediated TNF-related epithelial repair Myles, IA; Castillo, CR; Barbian, KD et al. Sci Transl Med, DOI://10.1126/scitranslmed.aaz8631 (2020)
- Comparative Transcriptomics Analyses in Livers of Mice, Humans, and Humanized Mice Define Human-Specific Gene Networks Jiang, C; Li, P; Ruan, X et al. Cells, DOI://10.3390/cells9122566 (2020)
- IBEX: A versatile multiplex optical imaging approach for deep phenotyping and spatial analysis of cells in complex tissues Radtke, AJ; Kandov, E; Lowekamp, B et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2018488117 (2020)
- The Central Role of Salivary Metalloproteases in Host Acquired Resistance to Tick Feeding Perner, J; Helm, D; Haberkant, P et al. Front Cell Infect Microbiol, DOI://10.3389/fcimb.2020.563349 (2020)
- Deficiency in the endocytic adaptor proteins PHETA1/2 impairs renal and craniofacial development Ates, KM; Wang, T; Moreland, T et al. Dis Model Mech, DOI://10.1242/dmm.041913 (2020)
- The outcome of TGFβ antagonism in metastatic breast cancer models in vivo reflects a complex balance between tumor-suppressive and pro-progression activities of TGFβ Yang, Y; Yang, HH; Tang, B et al. Clin Cancer Res, DOI://10.1158/1078-0432.CCR-19-2370 (2020)
- APOBEC3A catalyzes mutation and drives carcinogenesis in vivo Law, EK; Levin-Klein, R; Jarvis, MC et al. J Exp Med, DOI://10.1084/jem.20200261 (2020)
- Polygenic analysis of the effect of common and low-frequency genetic variants on serum uric acid levels in Korean individuals Cho, SK; Kim, B; Myung, W et al. Sci Rep, DOI://10.1038/s41598-020-66064-z (2020)
- Dynamics of genomic and immune responses during primary immunotherapy resistance in mismatch repair-deficient tumors Takahashi, N; Rajapakse, VN; Pongor, L et al. Cold Spring Harb Mol Case Stud, DOI://10.1101/mcs.a005678 (2020)
- Systematic investigation of synthetic polyelectrolyte bottlebrush solutions by neutron and dynamic light scattering, osmometry, and molecular dynamics simulation Horkay, F; Chremos, A; Douglas, JF et al. J Chem Phys, DOI://10.1063/5.0007271 (2020)
- Sex chromosome and sex locus characterization in goldfish, Carassius auratus (Linnaeus, 1758) Wen, M; Feron, R; Pan, Q et al. BMC Genomics, DOI://10.1186/s12864-020-06959-3 (2020)
- Structural insight into toxin secretion by contact-dependent growth inhibition transporters Guerin, J; Botos, I; Zhang, Z et al. Elife, DOI://10.7554/eLife.58100 (2020)
- An RNA Repair Operon Regulated by Damaged tRNAs Hughes, KJ; Chen, X; Burroughs, AM et al. Cell Rep, DOI://10.1016/j.celrep.2020.108527 (2020)
- Effect of sequence depth and length in long-read assembly of the maize inbred NC358 Ou, S; Liu, J; Chougule, KM et al. Nat Commun, DOI://10.1038/s41467-020-16037-7 (2020)
- Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci de Las Fuentes, L; Sung, YJ; Noordam, R et al. Mol Psychiatry, DOI://10.1038/s41380-020-0719-3 (2020)
- Rapid image deconvolution and multiview fusion for optical microscopy Guo, M; Li, Y; Su, Y et al. Nat Biotechnol, DOI://10.1038/s41587-020-0560-x (2020)
- Language lateralization from task-based and resting state functional MRI in patients with epilepsy Rolinski, R; You, X; Gonzalez-Castillo, J et al. Hum Brain Mapp, DOI://10.1002/hbm.25003 (2020)
- Strains used in whole organism Plasmodium falciparum vaccine trials differ in genome structure, sequence, and immunogenic potential Moser, KA; Drábek, EF; Dwivedi, A et al. Genome Med, DOI://10.1186/s13073-019-0708-9 (2020)
- A Serum Proteomic Signature Predicting Survival in Patients with Glioblastoma Sproull, M; Mathen, P; Miller, CA et al. J Biochem Anal Stud, DOI://10.16966/2576-5833.117 (2020)
- Impact of Conditioning Intensity of Allogeneic Transplantation for Acute Myeloid Leukemia With Genomic Evidence of Residual Disease Hourigan, CS; Dillon, LW; Gui, G et al. J Clin Oncol, DOI://10.1200/JCO.19.03011 (2020)
- BAMscale: quantification of next-generation sequencing peaks and generation of scaled coverage tracks Pongor, LS; Gross, JM; Vera Alvarez, R et al. Epigenetics Chromatin, DOI://10.1186/s13072-020-00343-x (2020)
- Uncoupling the Folding-Function Paradigm of Lytic Peptides to Deliver Impermeable Inhibitors of Intracellular Protein-Protein Interactions Miller, SE; Tsuji, K; Abrams, RPM et al. J Am Chem Soc, DOI://10.1021/jacs.0c07921 (2020)
- Genome-Wide Analysis of the FOXA1 Transcriptional Network Identifies Novel Protein-Coding and Long Noncoding RNA Targets in Colorectal Cancer Cells Lazar, SB; Pongor, L; Li, XL et al. Mol Cell Biol, DOI://10.1128/MCB.00224-20 (2020)
- Somatic structural variation targets neurodevelopmental genes and identifies SHANK2 as a tumor suppressor in neuroblastoma Lopez, G; Conkrite, KL; Doepner, M et al. Genome Res, DOI://10.1101/gr.252106.119 (2020)
- Use of word and graph embedding to measure semantic relatedness between Unified Medical Language System concepts Mao, Y; Fung, KW; , J Am Med Inform Assoc, DOI://10.1093/jamia/ocaa136 (2020)
- Zebrafish Posterior Lateral Line primordium migration requires interactions between a superficial sheath of motile cells and the skin Dalle Nogare, DE; Natesh, N; Vishwasrao, HD et al. Elife, DOI://10.7554/eLife.58251 (2020)
- bZIP Dimers CREB1, ATF2, Zta, ATF3|cJun, and cFos|cJun Prefer to Bind to Some Double-Stranded DNA Sequences Containing 5-Formylcytosine and 5-Carboxylcytosine Ray, S; Tillo, D; Ufot, A et al. Biochemistry, DOI://10.1021/acs.biochem.0c00475 (2020)
- Lipid flip-flop and desorption from supported lipid bilayers is independent of curvature Jing, H; Wang, Y; Desai, PR et al. PLoS One, DOI://10.1371/journal.pone.0244460 (2020)
- Repeat expansions confer WRN dependence in microsatellite-unstable cancers van Wietmarschen, N; Sridharan, S; Nathan, WJ et al. Nature, DOI://10.1038/s41586-020-2769-8 (2020)
- Metabolic but not transcriptional regulation by PKM2 is important for natural killer cell responses Walls, JF; Subleski, JJ; Palmieri, EM et al. Elife, DOI://10.7554/eLife.59166 (2020)
- Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 Zhang, Q; Bastard, P; Liu, Z et al. Science, DOI://10.1126/science.abd4570 (2020)
- mRNA vaccine-induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer Cafri, G; Gartner, JJ; Zaks, T et al. J Clin Invest, DOI://10.1172/JCI134915 (2020)
- Age and Tumor Differentiation-Associated Gene Expression Based Analysis of Non-Familial Prostate Cancers Sharad, S; Allemang, TC; Li, H et al. Front Oncol, DOI://10.3389/fonc.2020.584280 (2020)
- NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency Marques, JG; Gryder, BE; Pavlovic, B et al. Elife, DOI://10.7554/eLife.54993 (2020)
- Scale-Free Dynamics in Animal Groups and Brain Networks Ribeiro, TL; Chialvo, DR; Plenz, D; , Front Syst Neurosci, DOI://10.3389/fnsys.2020.591210 (2020)
- Progressive B Cell Loss in Revertant X-SCID Lin, CH; Kuehn, HS; Thauland, TJ et al. J Clin Immunol, DOI://10.1007/s10875-020-00825-3 (2020)
- Correction to: A Nonsense N -Terminus NFKB2 Mutation Leading to Haploinsufficiency in a Patient with a Predominantly Antibody Deficiency Kuehn, HS; Bernasconi, A; Niemela, JE et al. J Clin Immunol, DOI://10.1007/s10875-020-00860-0 (2020)
- Case Report: Single-Cell Transcriptomic Analysis of an Anaplastic Oligodendroglioma Post Immunotherapy Yu, G; Butler, MK; Abdelmaksoud, A et al. Front Oncol, DOI://10.3389/fonc.2020.601452 (2020)
- Integrated analysis of genome-wide miRNAs and targeted gene expression in esophageal squamous cell carcinoma (ESCC) and relation to prognosis Yang, H; Su, H; Hu, N et al. BMC Cancer, DOI://10.1186/s12885-020-06901-6 (2020)
- G-Protein biased opioid agonists: 3-hydroxy- N-phenethyl-5-phenylmorphans with three-carbon chain substituents at C9 Gutman, ES; Bow, E; Li, F et al. RSC Med Chem, DOI://10.1039/d0md00104j (2020)
- Author Correction: Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma Brudno, JN; Lam, N; Vanasse, D et al. Nat Med, DOI://10.1038/s41591-020-0864-x (2020)
- Mutations in CERKL and RP1 cause retinitis pigmentosa in Pakistani families Nadeem, R; Kabir, F; Li, J et al. Hum Genome Var, DOI://10.1038/s41439-020-0100-8 (2020)
- Emx2 regulates hair cell rearrangement but not positional identity within neuromasts Ohta, S; Ji, YR; Martin, D; Wu, DK; , Elife, DOI://10.7554/eLife.60432 (2020)
- NCINM: organ dose calculator for patients undergoing nuclear medicine procedures Villoing, D; Cuthbert, TA; Kitahara, CM; Lee, C; , Biomed Phys Eng Express, DOI://10.1088/2057-1976/aba41e (2020)
- Genetic determinants of survival in progressive supranuclear palsy: a genome-wide association study Jabbari, E; Koga, S; Valentino, RR et al. Lancet Neurol, DOI://10.1016/S1474-4422(20)30394-X (2020)
- Zika Virus-Induced Neuronal Apoptosis via Increased Mitochondrial Fragmentation Yang, S; Gorshkov, K; Lee, EM et al. Front Microbiol, DOI://10.3389/fmicb.2020.598203 (2020)
- Assessment of LIN28A variants in Parkinson's disease in large European cohorts Diez-Fairen, M; Makarious, MB; Bandres-Ciga, S; Blauwendraat, C; , ; , Neurobiol Aging, DOI://10.1016/j.neurobiolaging.2020.12.002 (2020)
- Gene Expression Profiling of Mediastinal Gray Zone Lymphoma and Its Relationship to Primary Mediastinal B-cell Lymphoma and Classical Hodgkin Lymphoma Pittaluga, S; Nicolae, A; Wright, GW et al. Blood Cancer Discov, DOI://10.1158/2643-3230.BCD-20-0009 (2020)
- Loss of myeloid-specific lamin A/C drives lung metastasis through Gfi-1 and C/EBPε-mediated granulocytic differentiation Ishii, H; Park, WY; So, J et al. Mol Carcinog, DOI://10.1002/mc.23147 (2020)
- Lipidomic profiling identifies signatures of metabolic risk Yin, X; Willinger, CM; Keefe, J et al. EBioMedicine, DOI://10.1016/j.ebiom.2019.10.046 (2020)
- Synthetic Lethal Drug Combinations Targeting Proteasome and Histone Deacetylase Inhibitors in TP53-Mutated Cancers Das, S; Deng, X; Camphausen, K; Shankavaram, U; , Arch Cancer Biol Ther (2020)
- PAX1 is essential for development and function of the human thymus Yamazaki, Y; Urrutia, R; Franco, LM et al. Sci Immunol, DOI://10.1126/sciimmunol.aax1036 (2020)
- A three-dimensional potential of mean force to improve backbone and sidechain hydrogen bond geometry in Xplor-NIH protein structure determination Schwieters, CD; Bermejo, GA; Clore, GM; , Protein Sci, DOI://10.1002/pro.3745 (2020)
- IRBIT Directs Differentiation of Intestinal Stem Cell Progeny to Maintain Tissue Homeostasis Arnaoutov, A; Lee, H; Plevock Haase, K et al. iScience, DOI://10.1016/j.isci.2020.100954 (2020)
- Longitudinal changes in network homogeneity in presymptomatic C9orf72 mutation carriers Waugh, RE; Danielian, LE; Shoukry, RFS; Floeter, MK; , Neurobiol Aging, DOI://10.1016/j.neurobiolaging.2020.11.014 (2020)
- Progressive multifocal leukoencephalopathy lesion and brain parenchymal segmentation from MRI using serial deep convolutional neural networks Al-Louzi, O; Roy, S; Osuorah, I et al. Neuroimage Clin, DOI://10.1016/j.nicl.2020.102499 (2020)
- Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis Dewan, R; Chia, R; Ding, J et al. Neuron, DOI://10.1016/j.neuron.2020.11.005 (2020)
- The Evolutionary Dynamics of Influenza A Viruses Circulating in Mallards in Duck Hunting Preserves in Maryland, USA Trovão, NS; Nolting, JM; Slemons, RD; Nelson, MI; Bowman, AS; , Microorganisms, DOI://10.3390/microorganisms9010040 (2020)
- Enhancing Question Answering by Injecting Ontological Knowledge through Regularization Goodwin, TR; Demner-Fushman, D; , Proc Conf Empir Methods Nat Lang Process, DOI://10.18653/v1/2020.deelio-1.7 (2020)
- Towards Zero-Shot Conditional Summarization with Adaptive Multi-Task Fine-Tuning Goodwin, TR; Savery, ME; Demner-Fushman, D; , Proc Conf Empir Methods Nat Lang Process (2020)
- Matrix Drug Screen Identifies Synergistic Drug Combinations to Augment SMAC Mimetic Activity in Ovarian Cancer Noonan, AM; Cousins, A; Anderson, D et al. Cancers (Basel), DOI://10.3390/cancers12123784 (2020)
- Molecular Details of Protein Condensates Probed by Microsecond Long Atomistic Simulations Zheng, W; Dignon, GL; Jovic, N et al. J Phys Chem B, DOI://10.1021/acs.jpcb.0c10489 (2020)
- Loss of endocytosis-associated RabGEF1 causes aberrant morphogenesis and altered autophagy in photoreceptors leading to retinal degeneration Hargrove-Grimes, P; Mondal, AK; Gumerson, J et al. PLoS Genet, DOI://10.1371/journal.pgen.1009259 (2020)
- Evolving schema representations in orbitofrontal ensembles during learning Zhou, J; Jia, C; Montesinos-Cartagena, M; Gardner, MPH; Zong, W; Schoenbaum, G; , Nature, DOI://10.1038/s41586-020-03061-2 (2020)
- Activation of Interferon-Stimulated Transcriptomes and ACE2 Isoforms in Human Airway Epithelium Is Curbed by Janus Kinase Inhibitors Lee, HK; Jung, O; Hennighausen, L; , Res Sq, DOI://10.21203/rs.3.rs-119695/v1 (2020)
- Seeker: alignment-free identification of bacteriophage genomes by deep learning Auslander, N; Gussow, AB; Benler, S; Wolf, YI; Koonin, EV; , Nucleic Acids Res, DOI://10.1093/nar/gkaa856 (2020)
- Cancer prognosis with shallow tumor RNA sequencing Milanez-Almeida, P; Martins, AJ; Germain, RN; Tsang, JS; , Nat Med, DOI://10.1038/s41591-019-0729-3 (2020)
- LAMP3 induces apoptosis and autoantigen release in Sjögren's syndrome patients Tanaka, T; Warner, BM; Odani, T et al. Sci Rep, DOI://10.1038/s41598-020-71669-5 (2020)
- Disseminated Mycobacterium marinum in HIV unmasked by Immune Reconstitution Inflammatory Syndrome Manion, M; Dulanto Chiang, A; Pei, L et al. J Infect Dis, DOI://10.1093/infdis/jiaa769 (2020)
- Resting State Functional Connectivity Is Decreased Globally Across the C9orf72 Mutation Spectrum Smallwood Shoukry, RF; Clark, MG; Floeter, MK; , Front Neurol, DOI://10.3389/fneur.2020.598474 (2020)
- An Integrated Epigenomic and Transcriptomic Map of Mouse and Human αβ T Cell Development Chopp, LB; Gopalan, V; Ciucci, T et al. Immunity, DOI://10.1016/j.immuni.2020.10.024 (2020)
- Identification of a novel long-acting 4'-modified nucleoside reverse transcriptase inhibitor against HBV Higashi-Kuwata, N; Hayashi, S; Kumamoto, H et al. J Hepatol, DOI://10.1016/j.jhep.2020.12.006 (2020)
- A Deep Learning Pipeline for Nucleus Segmentation Zaki, G; Gudla, PR; Lee, K et al. Cytometry A, DOI://10.1002/cyto.a.24257 (2020)
- Identification of a pathogenic intronic KIF5A mutation in an ALS-FTD kindred Saez-Atienzar, S; Dalgard, CL; Ding, J et al. Neurology, DOI://10.1212/WNL.0000000000011064 (2020)
- Ubiquitination of MHC Class II by March-I Regulates Dendritic Cell Fitness Kim, HJ; Bandola-Simon, J; Ishido, S et al. J Immunol, DOI://10.4049/jimmunol.2000975 (2020)
- Peptide-MHC Binding Reveals Conserved Allosteric Sites in MHC Class I- and Class II-Restricted T Cell Receptors (TCRs) He, Y; Agnihotri, P; Rangarajan, S et al. J Mol Biol, DOI://10.1016/j.jmb.2020.10.031 (2020)
- Generation of a Single-Cell RNAseq Atlas of Murine Salivary Gland Development Hauser, BR; Aure, MH; Kelly, MC; , ; Hoffman, MP; Chibly, AM; , iScience, DOI://10.1016/j.isci.2020.101838 (2020)
- Plasma proteomic biomarker signature of age predicts health and life span Tanaka, T; Basisty, N; Fantoni, G et al. Elife, DOI://10.7554/eLife.61073 (2020)
- Flight of the PEGASUS? Comparing Transformers on Few-Shot and Zero-Shot Multi-document Abstractive Summarization Goodwin, TR; Savery, ME; Demner-Fushman, D; , Proc Int Conf Comput Ling, 1525-2477 (2020)
- Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer Krishna, S; Lowery, FJ; Copeland, AR et al. Science, DOI://10.1126/science.abb9847 (2020)
- Data sets on human histone interaction networks Peng, Y; Markov, Y; Goncearenco, A et al. Data Brief, DOI://10.1016/j.dib.2020.106555 (2020)
- Identification of Genes Contributing to a Long Circadian Period in Drosophila Melanogaster Kumar, S; Tunc, I; Tansey, TR; Pirooznia, M; Harbison, ST; , J Biol Rhythms, DOI://10.1177/0748730420975946 (2020)
- Natural selection on sleep duration in Drosophila melanogaster Souto-Maior, C; Serrano Negron, YL; Harbison, ST; , Sci Rep, DOI://10.1038/s41598-020-77680-0 (2020)
- Polyelectrolyte interactions enable rapid association and dissociation in high-affinity disordered protein complexes Sottini, A; Borgia, A; Borgia, MB et al. Nat Commun, DOI://10.1038/s41467-020-18859-x (2020)
- Molecular structure and interactions within amyloid-like fibrils formed by a low-complexity protein sequence from FUS Lee, M; Ghosh, U; Thurber, KR; Kato, M; Tycko, R; , Nat Commun, DOI://10.1038/s41467-020-19512-3 (2020)
- Feedforward prediction error signals during episodic memory retrieval Haque, RU; Inati, SK; Levey, AI; Zaghloul, KA; , Nat Commun, DOI://10.1038/s41467-020-19828-0 (2020)
- Computational Investigation of Gantenerumab and Crenezumab Recognition of Aβ Fibrils in Alzheimer's Disease Brain Tissue Chen, Y; Wei, G; Zhao, J; Nussinov, R; Ma, B; , ACS Chem Neurosci, DOI://10.1021/acschemneuro.0c00364 (2020)
- Reliable segmentation of 2D cardiac magnetic resonance perfusion image sequences using time as the 3rd dimension Sandfort, V; Jacobs, M; Arai, AE; Hsu, LY; , Eur Radiol, DOI://10.1007/s00330-020-07474-5 (2020)
- A generalized workflow for conducting electric field-optimized, fMRI-guided, transcranial magnetic stimulation Balderston, NL; Roberts, C; Beydler, EM et al. Nat Protoc, DOI://10.1038/s41596-020-0387-4 (2020)
- Emergence of non-canonical parvalbumin-containing interneurons in hippocampus of a murine model of type I lissencephaly Ekins, TG; Mahadevan, V; Zhang, Y et al. Elife, DOI://10.7554/eLife.62373 (2020)
- Distinct Structures and Dynamics of Chromatosomes with Different Human Linker Histone Isoforms Zhou, BR; Feng, H; Kale, S et al. Mol Cell, DOI://10.1016/j.molcel.2020.10.038 (2020)
- A series of five population-specific Indian brain templates and atlases spanning ages 6-60 years Holla, B; Taylor, PA; Glen, DR et al. Hum Brain Mapp, DOI://10.1002/hbm.25182 (2020)
- A Heterogeneous Swine Show Circuit Drives Zoonotic Transmission of Influenza A Viruses in the United States Nelson, MI; Perofsky, A; McBride, DS et al. J Virol, DOI://10.1128/JVI.01453-20 (2020)
- Novel TMEM98, MFRP, PRSS56 variants in a large United States high hyperopia and nanophthalmos cohort Prasov, L; Guan, B; Ullah, E et al. Sci Rep, DOI://10.1038/s41598-020-76725-8 (2020)
- An immune-based biomarker signature is associated with mortality in COVID-19 patients Abers, MS; Delmonte, OM; Ricotta, EE et al. JCI Insight, DOI://10.1172/jci.insight.144455 (2020)
- Neanderthal-derived genetic variation is associated with functional connectivity in the brains of living humans Gregory, MD; Kippenhan, JS; Kohn, P et al. Brain Connect, DOI://10.1089/brain.2020.0809 (2020)
- SAVI, in silico generation of billions of easily synthesizable compounds through expert-system type rules Patel, H; Ihlenfeldt, WD; Judson, PN et al. Sci Data, DOI://10.1038/s41597-020-00727-4 (2020)
- Network Changes in Insula and Amygdala Connectivity Accompany Implicit Suicidal Associations Ballard, ED; Gilbert, JR; Fields, JS; Nugent, AC; Zarate, CA; , Front Psychiatry, DOI://10.3389/fpsyt.2020.577628 (2020)
- Statistical approaches using longitudinal biomarkers for disease early detection: A comparison of methodologies Han, Y; Albert, PS; Berg, CD; Wentzensen, N; Katki, HA; Liu, D; , Stat Med, DOI://10.1002/sim.8731 (2020)
- The sialotranscriptome of the gopher-tortoise tick, Amblyomma tuberculatum Karim, S; Kumar, D; Adamson, S; Ennen, JR; Qualls, CP; Ribeiro, JMC; , Ticks Tick Borne Dis, DOI://10.1016/j.ttbdis.2020.101560 (2020)
- Lack of pathogenic germline DICER1 variants in males with testicular germ-cell tumors Vasta, LM; McMaster, ML; Harney, LA et al. Cancer Genet, DOI://10.1016/j.cancergen.2020.10.002 (2020)
- Author Correction: Cryo-EM structure of the bacterial Ton motor subcomplex ExbB-ExbD provides information on structure and stoichiometry Celia, H; Botos, I; Ni, X et al. Commun Biol, DOI://10.1038/s42003-020-01427-w (2020)
- Accommodation of In-Register N-Linked Glycans on Prion Protein Amyloid Cores Artikis, E; Roy, A; Verli, H; Cordeiro, Y; Caughey, B; , ACS Chem Neurosci, DOI://10.1021/acschemneuro.0c00635 (2020)
- Coarse-grained modelling of DNA plectoneme pinning in the presence of base-pair mismatches Desai, PR; Brahmachari, S; Marko, JF; Das, S; Neuman, KC; , Nucleic Acids Res, DOI://10.1093/nar/gkaa836 (2020)
- Predicting the course of ADHD symptoms through the integration of childhood genomic, neural, and cognitive features Sudre, G; Sharp, W; Kundzicz, P et al. Mol Psychiatry, DOI://10.1038/s41380-020-00941-x (2020)
- Reversing the direction of drug transport mediated by the human multidrug transporter P-glycoprotein Sajid, A; Lusvarghi, S; Murakami, M et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2016270117 (2020)
- Rapid Enhancer Remodeling and Transcription Factor Repurposing Enable High Magnitude Gene Induction upon Acute Activation of NK Cells Sciumè, G; Mikami, Y; Jankovic, D et al. Immunity, DOI://10.1016/j.immuni.2020.09.008 (2020)
- Patients with anxiety disorders rely on bilateral dlPFC activation during verbal working memory Balderston, NL; Flook, E; Hsiung, A et al. Soc Cogn Affect Neurosci, DOI://10.1093/scan/nsaa146 (2020)
- Genetically predicted telomere length is associated with clonal somatic copy number alterations in peripheral leukocytes Brown, DW; Lin, SH; Loh, PR; Chanock, SJ; Savage, SA; Machiela, MJ; , PLoS Genet, DOI://10.1371/journal.pgen.1009078 (2020)
- Characterizing transcriptional regulatory sequences in coronaviruses and their role in recombination Yang, Y; Yan, W; Hall, AB; Jiang, X; , Mol Biol Evol, DOI://10.1093/molbev/msaa281 (2020)
- Vestibular phenotype-genotype correlation in a cohort of 90 patients with Usher syndrome Wafa, TT; Faridi, R; King, KA et al. Clin Genet, DOI://10.1111/cge.13868 (2020)
- FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age García-Prat, L; Perdiguero, E; Alonso-Martín, S et al. Nat Cell Biol, DOI://10.1038/s41556-020-00593-7 (2020)
- Mouse Models of Human Pathogenic Variants of TBC1D24 Associated with Non-Syndromic Deafness DFNB86 and DFNA65 and Syndromes Involving Deafness Tona, R; Lopez, IA; Fenollar-Ferrer, C et al. Genes (Basel), DOI://10.3390/genes11101122 (2020)
- Prevalent and sex-biased breathing patterns modify functional connectivity MRI in young adults Lynch, CJ; Silver, BM; Dubin, MJ et al. Nat Commun, DOI://10.1038/s41467-020-18974-9 (2020)
- Transcriptomes of Major Proximal Tubule Cell Culture Models Khundmiri, SJ; Chen, L; Lederer, ED; Yang, CR; Knepper, MA; , J Am Soc Nephrol, DOI://10.1681/ASN.2020010009 (2020)
- Tumor Phylogeny Topology Inference via Deep Learning Sadeqi Azer, E; Haghir Ebrahimabadi, M; Malikić, S et al. iScience, DOI://10.1016/j.isci.2020.101655 (2020)
- Critical Sequence Hotspots for Binding of Novel Coronavirus to Angiotensin Converter Enzyme as Evaluated by Molecular Simulations Ghorbani, M; Brooks, BR; Klauda, JB; , J Phys Chem B, DOI://10.1021/acs.jpcb.0c05994 (2020)
- Cancer-Specific Immune Prognostic Signature in Solid Tumors and Its Relation to Immune Checkpoint Therapies Das, S; Camphausen, K; Shankavaram, U; , Cancers (Basel), DOI://10.3390/cancers12092476 (2020)
- A physiologic overview of the organ-specific transcriptome of the cattle tick Rhipicephalus microplus Tirloni, L; Braz, G; Nunes, RD et al. Sci Rep, DOI://10.1038/s41598-020-75341-w (2020)
- An optimized protocol for retina single-cell RNA sequencing Fadl, BR; Brodie, SA; Malasky, M et al. Mol Vis, 1090-0535 (2020)
- Distinct contributions of cathelin-related antimicrobial peptide (CRAMP) derived from epithelial cells and macrophages to colon mucosal homeostasis Chen, K; Yoshimura, T; Yao, X et al. J Pathol, DOI://10.1002/path.5572 (2020)
- Embryonic erythropoiesis and hemoglobin switching require transcriptional repressor ETO2 to modulate chromatin organization Guo, X; Plank-Bazinet, J; Krivega, I; Dale, RK; Dean, A; , Nucleic Acids Res, DOI://10.1093/nar/gkaa736 (2020)
- Characterization of rare spindle and root cell transcriptional profiles in the stria vascularis of the adult mouse cochlea Gu, S; Olszewski, R; Taukulis, I et al. Sci Rep, DOI://10.1038/s41598-020-75238-8 (2020)
- Permutation inference for canonical correlation analysis Winkler, AM; Renaud, O; Smith, SM; Nichols, TE; , Neuroimage, DOI://10.1016/j.neuroimage.2020.117065 (2020)
- RNA-sequencing of the Nyssomyia neivai sialome: a sand fly-vector from a Brazilian endemic area for tegumentary leishmaniasis and pemphigus foliaceus Vernal, S; Oliveira, F; Oliveira, WHC et al. Sci Rep, DOI://10.1038/s41598-020-74343-y (2020)
- Whole genome sequencing data of multiple individuals of Pakistani descent Khan, SY; Ali, M; Lee, MW et al. Sci Data, DOI://10.1038/s41597-020-00664-2 (2020)
- Direct Comparison of (N)-Methanocarba and Ribose-Containing 2-Arylalkynyladenosine Derivatives as A 3 Receptor Agonists Tosh, DK; Salmaso, V; Rao, H et al. ACS Med Chem Lett, DOI://10.1021/acsmedchemlett.9b00637 (2020)
- Exploring the sequence fitness landscape of a bridge between protein folds Tian, P; Best, RB; , PLoS Comput Biol, DOI://10.1371/journal.pcbi.1008285 (2020)
- lncRNAKB, a knowledgebase of tissue-specific functional annotation and trait association of long noncoding RNA Seifuddin, F; Singh, K; Suresh, A et al. Sci Data, DOI://10.1038/s41597-020-00659-z (2020)
- Using whole-exome sequencing and protein interaction networks to prioritize candidate genes for germline cutaneous melanoma susceptibility Yepes, S; Tucker, MA; Koka, H et al. Sci Rep, DOI://10.1038/s41598-020-74293-5 (2020)
- Long-Term Cocaine Self-administration Produces Structural Brain Changes That Correlate With Altered Cognition Jedema, HP; Song, X; Aizenstein, HJ et al. Biol Psychiatry, DOI://10.1016/j.biopsych.2020.08.008 (2020)
- Interferons and viruses induce a novel truncated ACE2 isoform and not the full-length SARS-CoV-2 receptor Onabajo, OO; Banday, AR; Stanifer, ML et al. Nat Genet, DOI://10.1038/s41588-020-00731-9 (2020)
- Low-frequency variation near common germline susceptibility loci are associated with risk of Ewing sarcoma Lin, SH; Sampson, JN; Grünewald, TGP et al. PLoS One, DOI://10.1371/journal.pone.0237792 (2020)
- Dynamic Suppression of Average Facial Structure Shapes Neural Tuning in Three Macaque Face Patches Koyano, KW; Jones, AP; McMahon, DBT; Waidmann, EN; Russ, BE; Leopold, DA; , Curr Biol, DOI://10.1016/j.cub.2020.09.070 (2020)
- Response nonlinearities in networks of spiking neurons Sanzeni, A; Histed, MH; Brunel, N; , PLoS Comput Biol, DOI://10.1371/journal.pcbi.1008165 (2020)
- Body-size-dependent Iodine-131 S values Yeom, YS; Griffin, KT; Shin, B; Choi, C; Han, H; Moon, S; , J Radiol Prot, DOI://10.1088/1361-6498/abc053 (2020)
- Structural snapshots of the cellular folded protein translocation machinery Bcs1 Xia, D FEBS J, DOI://10.1111/febs.15576 (2020)
- Androgen receptor signaling regulates the transcriptome of prostate cancer cells by modulating global alternative splicing Shah, K; Gagliano, T; Garland, L et al. Oncogene, DOI://10.1038/s41388-020-01429-2 (2020)
- Activation of the SARS-CoV-2 Receptor Ace2 through JAK/STAT-Dependent Enhancers during Pregnancy Hennighausen, L; Lee, HK; , Cell Rep, DOI://10.1016/j.celrep.2020.108199 (2020)
- Exponential-Family Random Graph Models for Multi-Layer Networks Krivitsky, PN; Koehly, LM; Marcum, CS; , Psychometrika, DOI://10.1007/s11336-020-09720-7 (2020)
- Transcriptomic profiling of the digestive tract of the rat flea, Xenopsylla cheopis, following blood feeding and infection with Yersinia pestis Bland, DM; Martens, CA; Virtaneva, K et al. PLoS Negl Trop Dis, DOI://10.1371/journal.pntd.0008688 (2020)
- Genetic rescue of X-linked retinoschisis mouse (Rs1-/y) retina induces quiescence of the retinal microglial inflammatory state following AAV8-RS1 gene transfer and identifies gene networks underlying retinal recovery Vijayasarathy, C; Zeng, Y; Brooks, M; Fariss, RN; Sieving, PA; , Hum Gene Ther, DOI://10.1089/hum.2020.213 (2020)
- Membrane permeability of small molecules from unbiased molecular dynamics simulations Krämer, A; Ghysels, A; Wang, E et al. J Chem Phys, DOI://10.1063/5.0013429 (2020)
- Multiple capsid protein binding sites mediate selective packaging of the alphavirus genomic RNA Brown, RS; Anastasakis, DG; Hafner, M; Kielian, M; , Nat Commun, DOI://10.1038/s41467-020-18447-z (2020)
- Deregulated immune cell recruitment orchestrated by FOXM1 impairs human diabetic wound healing Sawaya, AP; Stone, RC; Brooks, SR et al. Nat Commun, DOI://10.1038/s41467-020-18276-0 (2020)
- Single-Cell RNA-Sequencing From Mouse Incisor Reveals Dental Epithelial Cell-Type Specific Genes Chiba, Y; Saito, K; Martin, D et al. Front Cell Dev Biol, DOI://10.3389/fcell.2020.00841 (2020)
- Projected Cancer Risks to Residents of New Mexico from Exposure to Trinity Radioactive Fallout Cahoon, EK; Zhang, R; Simon, SL; Bouville, A; Pfeiffer, RM; , Health Phys, DOI://10.1097/HP.0000000000001333 (2020)
- Merqury: reference-free quality, completeness, and phasing assessment for genome assemblies Rhie, A; Walenz, BP; Koren, S; Phillippy, AM; , Genome Biol, DOI://10.1186/s13059-020-02134-9 (2020)
- Synthetic lethal combination targeting BET uncovered intrinsic susceptibility of TNBC to ferroptosis Verma, N; Vinik, Y; Saroha, A et al. Sci Adv, DOI://10.1126/sciadv.aba8968 (2020)
- Polygenic risk score for the prediction of breast cancer is related to lesser terminal duct lobular unit involution of the breast Bodelon, C; Oh, H; Derkach, A et al. , DOI://10.1038/s41523-020-00184-7 (2020)
- Hybrid-DCA: A double asynchronous approach for stochastic dual coordinate ascent Pal, S; Xu, T; Yang, T; Rajasekaran, S; Bi, J; , , DOI://10.1016/j.jpdc.2020.04.002 (2020)
- In silico Drug Repurposing to combat COVID-19 based on Pharmacogenomics of Patient Transcriptomic Data Das, S; Camphausen, K; Shankavaram, U; , Res Sq, DOI://10.21203/rs.3.rs-39128/v1 (2020)
- Maternal-fetal genetic interactions, imprinting, and risk of placental abruption Workalemahu, T; Enquobahrie, DA; Gelaye, B et al. J Matern Fetal Neonatal Med, DOI://10.1080/14767058.2020.1822314 (2020)
- Subsequent Neoplasm Risk Associated With Rare Variants in DNA Damage Response and Clinical Radiation Sensitivity Syndrome Genes in the Childhood Cancer Survivor Study Morton, LM; Karyadi, DM; Hartley, SW et al. JCO Precis Oncol, DOI://10.1200/PO.20.00141 (2020)
- Organ Dose Conversion Coefficients Calculated for Korean Pediatric and Adult Voxel Phantoms Exposed to External Photon Fields Choonsik Lee, Yeon Soo Yeom, Keith Griffin, Choonik Lee, Ae-Kyoung Lee, Hyung-do Choi J. Radiat. Prot. Res, doi://10.14407/jrpr.2020.45.2.69 (2020)
- Power of Microbiome Beta-Diversity Analyses Based on Standard Reference Samples Gail, MH; Wan, Y; Shi, J; , Am J Epidemiol, DOI://10.1093/aje/kwaa204 (2020)
- The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction Yang, S; Zhang, Y; Ting, CY et al. Dev. Cell, DOI://10.1016/j.devcel.2020.08.006 (2020)
- Immune correlates analysis using vaccinees from test negative designs Follmann, DA; Dodd, L; , Biostatistics, DOI://10.1093/biostatistics/kxaa037 (2020)
- Atherosclerotic Plaque Burden on Abdominal CT: Automated Assessment With Deep Learning on Noncontrast and Contrast-enhanced Scans Summers, RM; Elton, DC; Lee, S et al. Acad Radiol, DOI://10.1016/j.acra.2020.08.022 (2020)
- Untangling the relatedness among correlations, part III: Inter-subject correlation analysis through Bayesian multilevel modeling for naturalistic scanning Chen, G; Taylor, PA; Qu, X et al. Neuroimage, DOI://10.1016/j.neuroimage.2019.116474 (2020)
- The role of RHOT1 and RHOT2 genetic variation on Parkinson disease risk and onset Periñán, MT; Gómez-Garre, P; Blauwendraat, C; Mir, P; Bandres-Ciga, S; , ; , Neurobiol Aging, DOI://10.1016/j.neurobiolaging.2020.07.003 (2020)
- Formation and Properties of a Self-Assembled Nanoparticle-Supported Lipid Bilayer Probed through Molecular Dynamics Simulations Jing, H; Wang, Y; Desai, PR; Ramamurthi, KS; Das, S; , Langmuir, DOI://10.1021/acs.langmuir.0c00593 (2020)
- Functional Dissection of Basal Ganglia Inhibitory Inputs onto Substantia Nigra Dopaminergic Neurons Evans, RC; Twedell, EL; Zhu, M; Ascencio, J; Zhang, R; Khaliq, ZM; , Cell Rep, DOI://10.1016/j.celrep.2020.108156 (2020)
- Liver Steatosis Categorization on Contrast-Enhanced CT Using a Fully-Automated Deep Learning Volumetric Segmentation Tool: Evaluation in 1,204 Heathy Adults Using Unenhanced CT as Reference Standard Pickhardt, PJ; Blake, GM; Graffy, PM et al. AJR Am J Roentgenol, DOI://10.2214/AJR.20.24415 (2020)
- RUNX1 and CBFβ-SMMHC transactivate target genes together in abnormal myeloid progenitors for leukemia development Zhen, T; Cao, Y; Ren, G et al. Blood, DOI://10.1182/blood.2020007747 (2020)
- Ketamine modulates fronto-striatal circuitry in depressed and healthy individuals Mkrtchian, A; Evans, JW; Kraus, C et al. Mol Psychiatry, DOI://10.1038/s41380-020-00878-1 (2020)
- Pan-cancer analysis of whole genomes ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium Nature, DOI://10.1038/s41586-020-1969-6 (2020)
- [Imaging of Tumor-Specific Hypoxia Dynamics and Its Significance in Radiation Biology] Yasui, H; Matsumoto, S; Inanami, O; Krishna, MC; , Igaku Butsuri, DOI://10.11323/jjmp.40.1_13 (2020)
- Structural Features that Distinguish Inactive and Active PI3K Lipid Kinases Zhang, M; Jang, H; Nussinov, R; , J. Mol. Biol., DOI://10.1016/j.jmb.2020.09.002 (2020)
- Targeting the PI3K/AKT Pathway Overcomes Enzalutamide Resistance by Inhibiting Induction of the Glucocorticoid Receptor Adelaiye-Ogala, R; Gryder, BE; Nguyen, YTM et al. Mol. Cancer Ther., DOI://10.1158/1535-7163.MCT-19-0936 (2020)
- Knockout of the caspase 8 associated protein 2 gene improves recombinant protein expression in HEK293 cells through up-regulation of the cyclin-dependent kinase inhibitor 2A gene Abaandou, L; Sharma, AK; Shiloach, J; , Biotechnol. Bioeng., DOI://10.1002/bit.27561 (2020)
- Voriconazole and the Risk of Keratinocyte Carcinomas Among Lung Transplant Recipients in the United States D'Arcy, ME; Pfeiffer, RM; Rivera, DR et al. JAMA Dermatol, DOI://10.1001/jamadermatol.2020.1141 (2020)
- Polygenic risk for anxiety influences anxiety comorbidity and suicidal behavior in bipolar disorder Lopes, FL; Zhu, K; Purves, KL et al. Transl Psychiatry, DOI://10.1038/s41398-020-00981-5 (2020)
- Contacting domains segregate a lipid transporter from a solute transporter in the malarial host-parasite interface Garten, M; Beck, JR; Roth, R et al. Nat Commun, DOI://10.1038/s41467-020-17506-9 (2020)
- Theta-burst TMS to the posterior superior temporal sulcus decreases resting-state fMRI connectivity across the face processing network Handwerker, DA; Ianni, G; Gutierrez, B et al. Netw Neurosci, DOI://10.1162/netn_a_00145 (2020)
- A mega-analysis of expression quantitative trait loci in retinal tissue Strunz, T; Kiel, C; Grassmann, F et al. PLoS Genet., DOI://10.1371/journal.pgen.1008934 (2020)
- Pharmacologic fibroblast reprogramming into photoreceptors restores vision Mahato, B; Kaya, KD; Fan, Y et al. Nature, DOI://10.1038/s41586-020-2201-4 (2020)
- Tracking the adaptation and compensation processes of patients brain arterial network to an evolving glioblastoma Zhu, J; Teolis, S; Biassou, N et al. IEEE Trans Pattern Anal Mach Intell, DOI://10.1109/TPAMI.2020.3008379 (2020)
- High throughput assessment of biomarkers in tissue microarrays using artificial intelligence: PTEN loss as a proof-of-principle in multi-center prostate cancer cohorts Harmon, SA; Patel, PG; Sanford, TH et al. Mod. Pathol., DOI://10.1038/s41379-020-00674-w (2020)
- Miswired Enhancer Logic Drives a Cancer of the Muscle Lineage Gryder, BE; Wachtel, M; Chang, K et al. iScience, DOI://10.1016/j.isci.2020.101103 (2020)
- Robust Accurate Identification and Biomass Estimates of Microorganisms via Tandem Mass Spectrometry Alves, G; Yu, YK; , J. Am. Soc. Mass Spectrom., DOI://10.1021/jasms.9b00035 (2020)
- Overexpression of ABCB1 and ABCG2 contributes to reduced efficacy of the PI3K/mTOR inhibitor samotolisib (LY3023414) in cancer cell lines Wu, CP; Hung, CY; Lusvarghi, S et al. Biochem. Pharmacol., DOI://10.1016/j.bcp.2020.114137 (2020)
- Automated CT biomarkers for opportunistic prediction of future cardiovascular events and mortality in an asymptomatic screening population: a retrospective cohort study Pickhardt, PJ; Graffy, PM; Zea, R et al. Lancet Digit Health, DOI://10.1016/S2589-7500(20)30025-X (2020)
- Lsh/HELLS is required for B lymphocyte development and immunoglobulin class switch recombination He, Y; Ren, J; Xu, X et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.2004112117 (2020)
- New Guinea highland wild dogs are the original New Guinea singing dogs Surbakti, S; Parker, HG; McIntyre, JK et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.2007242117 (2020)
- G-protein coupled receptor Gpr115 ( Adgrf4) is required for enamel mineralization mediated by ameloblasts Chiba, Y; Yoshizaki, K; Saito, K et al. J. Biol. Chem., DOI://10.1074/jbc.RA120.014281 (2020)
- TickSialoFam (TSFam): A Database That Helps to Classify Tick Salivary Proteins, a Review on Tick Salivary Protein Function and Evolution, With Considerations on the Tick Sialome Switching Phenomenon Ribeiro, JMC; Mans, BJ; Front Cell Infect Microbiol, DOI://10.3389/fcimb.2020.00374 (2020)
- Bedaquiline inhibits the yeast and human mitochondrial ATP synthases Luo, M; Zhou, W; Patel, H et al. Commun Biol, DOI://10.1038/s42003-020-01173-z (2020)
- Power calculation for the general two-sample Mendelian randomization analysis Deng, L; Zhang, H; Yu, K; , Genet Epidemiol, DOI://10.1002/gepi.22284 (2020)
- ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis Paiano, J; Wu, W; Yamada, S et al. Nat Commun, DOI://10.1038/s41467-020-14654-w (2020)
- Disome and Trisome Profiling Reveal Genome-wide Targets of Ribosome Quality Control Meydan, S; Guydosh, NR; Mol. Cell, DOI://10.1016/j.molcel.2020.06.010 (2020)
- A Peptide Derived from Lens Epithelium-Derived Growth Factor Stimulates HIV-1 DNA Integration and Facilitates Intasome Structural Studies Li, M; Chen, X; Wang, H; Jurado, KA; Engelman, AN; Craigie, R; J. Mol. Biol., DOI://10.1016/j.jmb.2020.01.040 (2020)
- Pathway identification through transcriptome analysis Terabayashi, T; Germino, GG; Menezes, LF; Cell. Signal., DOI://10.1016/j.cellsig.2020.109701 (2020)
- Phase-plate Cryo-electron Tomography Facilitates the Identification of Influenza Virus Condensed Core Structures John Gallagher , Neetu Gulati and Audray Harris Microscopy and Microanalysis, doi:10.1017/S1431927620017651 (2020)
- Phenotype stability under dynamic brain-tumor environment stimuli maps glioblastoma progression in patients Rajapakse, VN; Herrada, S; Lavi, O; , Sci Adv, DOI://10.1126/sciadv.aaz4125 (2020)
- GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 Infection Hattori, SI; Higshi-Kuwata, N; Raghavaiah, J et al. mBio, DOI://10.1128/mBio.01833-20 (2020)
- AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2 Yang, A; Shao, TJ; Bofill-De Ros, X et al. Nat Commun, DOI://10.1038/s41467-020-16533-w (2020)
- Protein kinase A inhibitor proteins (PKIs) divert GPCR-Gαs-cAMP signaling toward EPAC and ERK activation and are involved in tumor growth Hoy, JJ; Salinas Parra, N; Park, J; Kuhn, S; Iglesias-Bartolome, R; FASEB J., DOI://10.1096/fj.202001515R (2020)
- Whole Blood DNA Methylation Signatures of Diet Are Associated With Cardiovascular Disease Risk Factors and All-Cause Mortality Ma, J; Rebholz, CM; Braun, KVE et al. Circ Genom Precis Med, DOI://10.1161/CIRCGEN.119.002766 (2020)
- A Platelet Function Modulator of Thrombin Activation Is Causally Linked to Cardiovascular Disease and Affects PAR4 Receptor Signaling Rodriguez, BAT; Bhan, A; Beswick, A et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2020.06.008 (2020)
- Structure and Mechanism of DHHC Protein Acyltransferases Stix, R; Lee, CJ; Faraldo-Gómez, JD; Banerjee, A; J. Mol. Biol., DOI://10.1016/j.jmb.2020.05.023 (2020)
- Genome-wide Association Study Identifies HLA-DPB1 as a Significant Risk Factor for Severe Aplastic Anemia Savage, SA; Viard, M; O'hUigin, C et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2020.01.004 (2020)
- Retinal pigment epithelium transcriptome analysis in chronic smoking reveals a suppressed innate immune response and activation of differentiation pathways Wang, L; Kaya, KD; Kim, S et al. Free Radic. Biol. Med., DOI://10.1016/j.freeradbiomed.2020.06.004 (2020)
- A protocol for preparing explicitly solvated systems for stable molecular dynamics simulations Roe, DR; Brooks, BR; , J Chem Phys, DOI://10.1063/5.0013849 (2020)
- Transcription factor AP2 controls cnidarian germ cell induction DuBuc, TQ; Schnitzler, CE; Chrysostomou, E et al. Science, DOI://10.1126/science.aay6782 (2020)
- DONSON and FANCM associate with different replisomes distinguished by replication timing and chromatin domain Zhang, J; Bellani, MA; James, RC et al. Nat Commun, DOI://10.1038/s41467-020-17449-1 (2020)
- HiCanu: accurate assembly of segmental duplications, satellites, and allelic variants from high-fidelity long reads Nurk, S; Walenz, BP; Rhie, A et al. Genome Res., DOI://10.1101/gr.263566.120 (2020)
- High Levels of Chromosomal Copy Number Alterations and TP53 Mutations Correlate with Poor Outcome in Younger Breast Cancer Patients Koçak, A; Heselmeyer-Haddad, K; Lischka, A et al. Am. J. Pathol., DOI://10.1016/j.ajpath.2020.04.015 (2020)
- Estimating the Heritability of Developmental Change in Neural Connectivity, and Its Association With Changing Symptoms of Attention-Deficit/Hyperactivity Disorder Sudre, G; Bouyssi-Kobar, M; Norman, L; Sharp, W; Choudhury, S; Shaw, P; Biol. Psychiatry, DOI://10.1016/j.biopsych.2020.06.007 (2020)
- Diploid genome architecture revealed by multi-omic data of hybrid mice Han, Z; Cui, K; Placek, K et al. Genome Res., DOI://10.1101/gr.257568.119 (2020)
- Cryptic genetic variation enhances primate L1 retrotransposon survival by enlarging the functional coiled coil sequence space of ORF1p Furano, AV; Jones, CE; Periwal, V; Callahan, KE; Walser, JC; Cook, PR; PLoS Genet., DOI://10.1371/journal.pgen.1008991 (2020)
- Adapting CHMTRN (CHeMistry TRaNslator) for a New Use Judson, PN; Ihlenfeldt, WD; Patel, H; Delanne, V; Tarasova, N; Nicklaus, MC; , J Chem Inf Model, DOI://10.1021/acs.jcim.0c00448 (2020)
- Molecular mechanisms underlying menthol binding and activation of TRPM8 ion channel Xu, L; Han, Y; Chen, X et al. Nat Commun, DOI://10.1038/s41467-020-17582-x (2020)
- White matter microstructure in youth with and at risk for bipolar disorder Linke, JO; Stavish, C; Adleman, NE et al. Bipolar Disord, DOI://10.1111/bdi.12885 (2020)
- Dose-dependent activation of gene expression is achieved using CRISPR and small molecules that recruit endogenous chromatin machinery Chiarella, AM; Butler, KV; Gryder, BE et al. Nat. Biotechnol., DOI://10.1038/s41587-019-0296-7 (2020)
- Licochalcone A Selectively Resensitizes ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Drugs Wu, CP; Lusvarghi, S; Hsiao, SH et al. J. Nat. Prod., DOI://10.1021/acs.jnatprod.9b01022 (2020)
- Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome Chen, X; Dorris, Z; Shi, D et al. Structure, DOI://10.1016/j.str.2020.07.011 (2020)
- Exploration of Alternative Scaffolds for P2Y 14 Receptor Antagonists Containing a Biaryl Core Jung, YH; Yu, J; Wen, Z et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.0c00745 (2020)
- A preliminary study on functional activation and connectivity during frustration in youths with bipolar disorder Ross, AJ; Roule, AL; Deveney, CM et al. Bipolar Disord, DOI://10.1111/bdi.12985 (2020)
- Impact of Cysteine Residues on MHC Binding Predictions and Recognition by Tumor-Reactive T Cells Sachs, A; Moore, E; Kosaloglu-Yalcin, Z et al. J. Immunol., DOI://10.4049/jimmunol.1901173 (2020)
- Integrative Genomic Analysis Reveals Four Protein Biomarkers for Platelet Traits Lee, DH; Yao, C; Bhan, A et al. Circ. Res., DOI://10.1161/CIRCRESAHA.119.316447 (2020)
- Topoisomerase 3β knockout mice show transcriptional and behavioural impairments associated with neurogenesis and synaptic plasticity Joo, Y; Xue, Y; Wang, Y et al. Nat Commun, DOI://10.1038/s41467-020-16884-4 (2020)
- Hsd17b13 Deficiency Does not Protect Mice From Obesogenic Diet Injury Ma, Y; Brown, PM; Lin, DD et al. Hepatology, DOI://10.1002/hep.31517 (2020)
- Automated Abdominal CT Imaging Biomarkers for Opportunistic Prediction of Future Major Osteoporotic Fractures in Asymptomatic Adults Pickhardt, PJ; Graffy, PM; Zea, R et al. Radiology, DOI://10.1148/radiol.2020200466 (2020)
- Opportunistic Screening for Metabolic Syndrome in Asymptomatic Adults Utilizing Fully Automated Abdominal CT-based Biomarkers Pickhardt, PJ; Graffy, PM; Zea, R et al. AJR Am J Roentgenol, DOI://10.2214/AJR.20.23049 (2020)
- Transcriptional variation of sensory-related genes in natural populations of Aedes albopictus Gomulski, LM; Manni, M; Carraretto, D et al. BMC Genomics, DOI://10.1186/s12864-020-06956-6 (2020)
- Artificial neural networks for the inverse design of nanoparticles with preferential nano-bio behaviors Hassan, SA J Chem Phys, DOI://10.1063/5.0013990 (2020)
- Longitudinal changes in resting state networks in early presymptomatic carriers of C9orf72 expansions Shoukry, RS; Waugh, R; Bartlett, D; Raitcheva, D; Floeter, MK; Neuroimage Clin, DOI://10.1016/j.nicl.2020.102354 (2020)
- SOS1 interacts with Grb2 through regions that induce closed nSH3 conformations Liao, TJ; Jang, H; Fushman, D; Nussinov, R; J Chem Phys, DOI://10.1063/5.0013926 (2020)
- Impaired angiogenesis and extracellular matrix metabolism in autosomal-dominant hyper-IgE syndrome Dmitrieva, NI; Walts, AD; Nguyen, DP et al. J. Clin. Invest., DOI://10.1172/JCI135490 (2020)
- Blood DNA methylation sites predict death risk in a longitudinal study of 12, 300 individuals Colicino, E; Marioni, R; Ward-Caviness, C et al. Aging (Albany NY), DOI://10.18632/aging.103408 (2020)
- TREML4 Promotes Inflammatory Programs in Human and Murine Macrophages and Alters Atherosclerosis Lesion Composition in the Apolipoprotein E Deficient Mouse Gonzalez-Cotto, M; Guo, L; Karwan, M et al. Front Immunol, DOI://10.3389/fimmu.2020.00397 (2020)
- Integrative structural, functional, and transcriptomic analyses of sex-biased brain organization in humans Liu, S; Seidlitz, J; Blumenthal, JD; Clasen, LS; Raznahan, A; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1919091117 (2020)
- A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity Sanchez-Soto, M; Verma, RK; Willette, BKA et al. Sci Signal, DOI://10.1126/scisignal.aaw5885 (2020)
- Quantitative method for estimating stain density in electron microscopy of conventionally prepared biological specimens Fera, A; He, Q; Zhang, G; Leapman, RD; J Microsc, DOI://10.1111/jmi.12865 (2020)
- Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders Seidlitz, J; Nadig, A; Liu, S et al. Nat Commun, DOI://10.1038/s41467-020-17051-5 (2020)
- Cutting antiparallel DNA strands in a single active site Chen, X; Cui, Y; Best, RB et al. Nat. Struct. Mol. Biol., DOI://10.1038/s41594-019-0363-2 (2020)
- Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets Psaila, B; Wang, G; Rodriguez-Meira, A et al. Mol. Cell, DOI://10.1016/j.molcel.2020.04.008 (2020)
- RNA-RNA Interactomes of ProQ and Hfq Reveal Overlapping and Competing Roles Melamed, S; Adams, PP; Zhang, A; Zhang, H; Storz, G; Mol. Cell, DOI://10.1016/j.molcel.2019.10.022 (2020)
- HIV-associated gut dysbiosis is independent of sexual practice and correlates with noncommunicable diseases Vujkovic-Cvijin, I; Sortino, O; Verheij, E et al. Nat Commun, DOI://10.1038/s41467-020-16222-8 (2020)
- In Silico Drug Design for Purinergic GPCRs: Overview on Molecular Dynamics Applied to Adenosine and P2Y Receptors Salmaso, V; Jacobson, KA; Biomolecules, DOI://10.3390/biom10060812 (2020)
- In vitro and in vivo identification of clinically approved drugs that modify ACE2 expression Sinha, S; Cheng, K; Schäffer, AA; Aldape, K; Schiff, E; Ruppin, E; Mol. Syst. Biol., DOI://10.15252/msb.20209628 (2020)
- Novel metabolic role for BDNF in pancreatic β-cell insulin secretion Fulgenzi, G; Hong, Z; Tomassoni-Ardori, F et al. Nat Commun, DOI://10.1038/s41467-020-15833-5 (2020)
- Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model Cheng, RYS; Patel, NL; Back, T et al. J Vis Exp, DOI://10.3791/60316 (2020)
- Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism Gupta, S; Nakabo, S; Blanco, LP et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.2003603117 (2020)
- A dose voxel kernel method for rapid reconstruction of out-of-field neutron dose of patients in pencil beam scanning (PBS) proton therapy Yeom, YS; Griffin, KT; Mille, M; Jung, JW; Lee, C; Lee, C; Phys Med Biol, DOI://10.1088/1361-6560/abaa5f (2020)
- An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity Debruycker, V; Hutchin, A; Masureel, M et al. Nat. Struct. Mol. Biol., DOI://10.1038/s41594-020-0464-y (2020)
- Genotype of CDC73 germline mutation determines risk of parathyroid cancer Li, Y; Zhang, J; Adikaram, PR et al. Endocr. Relat. Cancer, DOI://10.1530/ERC-20-0149 (2020)
- EXOSC10 sculpts the transcriptome during the growth-to-maturation transition in mouse oocytes Wu, D; Dean, J; Nucleic Acids Res., DOI://10.1093/nar/gkaa249 (2020)
- Different mechanisms for translocation by monomeric and hexameric helicases Gao, Y; Yang, W; Curr. Opin. Struct. Biol., DOI://10.1016/j.sbi.2019.10.003 (2020)
- SARS-CoV2 drives JAK1/2-dependent local and systemic complement hyper-activation Yan, B; Freiwald, T; et al researchsquare, doi://10.21203/rs.3.rs-33390/v1 (2020)
- A Viral Exposure Signature Defines Early Onset of Hepatocellular Carcinoma Liu, J; Tang, W; Budhu, A et al. Cell, DOI://10.1016/j.cell.2020.05.038 (2020)
- Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing Riva, L; Yuan, S; Yin, X et al. Nature, DOI://10.1038/s41586-020-2577-1 (2020)
- Laterally Resolved Small-Angle Scattering Intensity from Lipid Bilayer Simulations: An Exact and a Limited-Range Treatment Dorrell, MW; Heberle, FA; Katsaras, J; Maibaum, L; Lyman, E; Sodt, AJ; J Chem Theory Comput, DOI://10.1021/acs.jctc.0c00132 (2020)
- Activation and inhibition of nonsense-mediated mRNA decay control the abundance of alternative polyadenylation products Kishor, A; Fritz, SE; Haque, N et al. Nucleic Acids Res., DOI://10.1093/nar/gkaa491 (2020)
- Trehalose as an alternative to glycerol as a glassing agent for in vivo DNP MRI Brender, JR; Kishimoto, S; Eaton, GR et al. Magn Reson Med, DOI://10.1002/mrm.28405 (2020)
- Molecular mechanisms underlying milk production and viviparity in the cockroach, Diploptera punctata Jennings, EC; Korthauer, MW; Hendershot, JM et al. Insect Biochem. Mol. Biol., DOI://10.1016/j.ibmb.2020.103333 (2020)
- Broad immune activation underlies shared set point signatures for vaccine responsiveness in healthy individuals and disease activity in patients with lupus Kotliarov, Y; Sparks, R; Martins, AJ et al. Nat. Med., DOI://10.1038/s41591-020-0769-8 (2020)
- Positioning Heterochromatin at the Nuclear Periphery Suppresses Histone Turnover to Promote Epigenetic Inheritance Holla, S; Dhakshnamoorthy, J; Folco, HD et al. Cell, DOI://10.1016/j.cell.2019.12.004 (2020)
- Automated glioma grading on conventional MRI images using deep convolutional neural networks Zhuge, Y; Ning, H; Mathen, P et al. Med Phys, DOI://10.1002/mp.14168 (2020)
- Penetrance of Parkinson's Disease in LRRK2 p.G2019S Carriers Is Modified by a Polygenic Risk Score Iwaki, H; Blauwendraat, C; Makarious, MB et al. Mov. Disord., DOI://10.1002/mds.27974 (2020)
- Resource: A multi-species multi-timepoint transcriptome database and webpage for the pineal gland and retina Chang, E; Fu, C; Coon, SL et al. J. Pineal Res., DOI://10.1111/jpi.12673 (2020)
- Targeted therapy guided by single-cell transcriptomic analysis in drug-induced hypersensitivity syndrome: a case report Kim, D; Kobayashi, T; Voisin, B et al. Nat. Med., DOI://10.1038/s41591-019-0733-7 (2020)
- Nanopore sequencing and the Shasta toolkit enable efficient de novo assembly of eleven human genomes Shafin, K; Pesout, T; Lorig-Roach, R et al. Nat. Biotechnol., DOI://10.1038/s41587-020-0503-6 (2020)
- An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis Xiang, G; Keller, CA; Heuston, E et al. Genome Res., DOI://10.1101/gr.255760.119 (2020)
- PLD2-PI(4,5)P2 interactions in fluid phase membranes: Structural modeling and molecular dynamics simulations Han, K; Pastor, RW; Fenollar-Ferrer, C; PLoS ONE, DOI://10.1371/journal.pone.0236201 (2020)
- Age Differences in the Neural Correlates of Anxiety Disorders: An fMRI Study of Response to Learned Threat Gold, AL; Abend, R; Britton, JC et al. Am J Psychiatry, DOI://10.1176/appi.ajp.2019.19060650 (2020)
- Differential Expression of the Transcription Factor GATA3 Specifies Lineage and Functions of Innate Lymphoid Cells Zhong, C; Zheng, M; Cui, K et al. Immunity, DOI://10.1016/j.immuni.2019.12.001 (2020)
- MEIS1 down-regulation by MYC mediates prostate cancer development through elevated HOXB13 expression and AR activity Whitlock, NC; Trostel, SY; Wilkinson, S et al. Oncogene, DOI://10.1038/s41388-020-01389-7 (2020)
- Maternal cardiometabolic factors and genetic ancestry influence epigenetic aging of the placenta Workalemahu, T; Shrestha, D; Tajuddin, SM; Tekola-Ayele, F; J Dev Orig Health Dis, DOI://10.1017/S2040174419000801 (2020)
- Identification of conserved evolutionary trajectories in tumors Hodzic, E; Shrestha, R; Malikic, S et al. Bioinformatics, DOI://10.1093/bioinformatics/btaa453 (2020)
- Drugs Targeting Tumor-Initiating Cells Prolong Survival in a Post-Surgery, Post-Chemotherapy Ovarian Cancer Relapse Model Harrington, BS; Ozaki, MK; Caminear, MW et al. Cancers (Basel), DOI://10.3390/cancers12061645 (2020)
- PhISCS-BnB: a fast branch and bound algorithm for the perfect tumor phylogeny reconstruction problem Sadeqi Azer, E; Rashidi Mehrabadi, F; Malikić, S et al. Bioinformatics, DOI://10.1093/bioinformatics/btaa464 (2020)
- Early pregnancy dyslipidemia is associated with placental DNA methylation at loci relevant for cardiometabolic diseases Ouidir, M; Zeng, X; Workalemahu, T et al. Epigenomics, DOI://10.2217/epi-2019-0293 (2020)
- The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter Plenge, P; Abramyan, AM; Sørensen, G et al. Nat Commun, DOI://10.1038/s41467-020-15292-y (2020)
- Epigenome-wide association study of DNA methylation and microRNA expression highlights novel pathways for human complex traits Huan, T; Mendelson, M; Joehanes, R et al. Epigenetics, DOI://10.1080/15592294.2019.1640547 (2020)
- Integrated analysis of sialotranscriptome and sialoproteome of the brown dog tick Rhipicephalus sanguineus (s.l.): Insights into gene expression during blood feeding Tirloni, L; Lu, S; Calvo, E et al. J Proteomics, DOI://10.1016/j.jprot.2020.103899 (2020)
- Structural basis of seamless excision and specific targeting by piggyBac transposase Chen, Q; Luo, W; Veach, RA; Hickman, AB; Wilson, MH; Dyda, F; Nat Commun, DOI://10.1038/s41467-020-17128-1 (2020)
- Telomere-to-telomere assembly of a complete human X chromosome Miga, KH; Koren, S; Rhie, A et al. Nature, DOI://10.1038/s41586-020-2547-7 (2020)
- Chromatin remodeler Ino80C acts independently of H2A.Z to evict promoter nucleosomes and stimulate transcription of highly expressed genes in yeast Qiu, H; Biernat, E; Govind, CK et al. Nucleic Acids Res., DOI://10.1093/nar/gkaa571 (2020)
- Human Herpesvirus 6 Detection in Alzheimer's Disease Cases and Controls across Multiple Cohorts Allnutt, MA; Johnson, K; Bennett, DA et al. Neuron, DOI://10.1016/j.neuron.2019.12.031 (2020)
- Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus Goel, RR; Wang, X; O'Neil, LJ et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1916897117 (2020)
- Genome-wide admixture mapping of DSM-IV alcohol dependence, criterion count, and the self-rating of the effects of ethanol in African American populations Lai, D; Kapoor, M; Wetherill, L et al. Am. J. Med. Genet. B Neuropsychiatr. Genet., DOI://10.1002/ajmg.b.32805 (2020)
- Concentrations of persistent organic pollutants in maternal plasma and epigenome-wide placental DNA methylation Ouidir, M; Mendola, P; Buck Louis, GM; Kannan, K; Zhang, C; Tekola-Ayele, F; Clin Epigenetics, DOI://10.1186/s13148-020-00894-6 (2020)
- Structural insight into mitochondrial β-barrel outer membrane protein biogenesis Diederichs, KA; Ni, X; Rollauer, SE et al. Nat Commun, DOI://10.1038/s41467-020-17144-1 (2020)
- Epigenetic Regulation of DNA Repair Pathway Choice by MacroH2A1 Splice Variants Ensures Genome Stability Sebastian, R; Hosogane, EK; Sun, EG et al. Mol. Cell, DOI://10.1016/j.molcel.2020.06.028 (2020)
- XAF1 as a modifier of p53 function and cancer susceptibility Pinto, EM; Figueiredo, BC; Chen, W et al. Sci Adv, DOI://10.1126/sciadv.aba3231 (2020)
- Evaluation of the Anti-Tumor Activity of the Humanized Monoclonal Antibody NEO-201 in Preclinical Models of Ovarian Cancer Zeligs, KP; Morelli, MP; David, JM et al. Front Oncol, DOI://10.3389/fonc.2020.00805 (2020)
- Genome-wide association study data reveal genetic susceptibility to chronic inflammatory intestinal diseases and pancreatic ductal adenocarcinoma risk Yuan, F; Hung, RJ; Walsh, N et al. Cancer Res., DOI://10.1158/0008-5472.CAN-20-0447 (2020)
- Soy protein nanofiber scaffolds for uniform maturation of hiPSC-derived retinal pigment epithelium Phelan, MA; Kruczek, K; Wilson, JP et al. Tissue Eng Part C Methods, DOI://10.1089/ten.TEC.2020.0072 (2020)
- Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury Wilflingseder, J; Willi, M; Lee, HK et al. Nat Commun, DOI://10.1038/s41467-020-17205-5 (2020)
- Deficiency of Adenosine Deaminase 2 (DADA2): Hidden Variants, Reduced Penetrance, and Unusual Inheritance Schnappauf, O; Zhou, Q; Moura, NS et al. J. Clin. Immunol., DOI://10.1007/s10875-020-00817-3 (2020)
- Comparison of Oral Microbiota Collected Using Multiple Methods and Recommendations for New Epidemiologic Studies Yano, Y; Hua, X; Wan, Y et al. mSystems, DOI://10.1128/mSystems.00156-20 (2020)
- Update of the CHARMM36 United Atom Chain Model for Hydrocarbons and Phospholipids Yu, Y; Klauda, JB; J Phys Chem B, DOI://10.1021/acs.jpcb.0c04795 (2020)
- The Intriguing Effects of Substituents in the N-Phenethyl Moiety of Norhydromorphone: A Bifunctional Opioid from a Set of 'Tail Wags Dog' Experiments Wang, M; Irvin, TC; Herdman, CA et al. Molecules, DOI://10.3390/molecules25112640 (2020)
- FIGLA, LHX8 and SOHLH1 transcription factor networks regulate mouse oocyte growth and differentiation Wang, Z; Liu, CY; Zhao, Y; Dean, J; Nucleic Acids Res., DOI://10.1093/nar/gkaa101 (2020)
- Structure of E3 ligase E6AP with a proteasome-binding site provided by substrate receptor hRpn10 Buel, GR; Chen, X; Chari, R et al. Nat Commun, DOI://10.1038/s41467-020-15073-7 (2020)
- Single atom changes in newly synthesized HIV protease inhibitors reveal structural basis for extreme affinity, high genetic barrier, and adaptation to the HIV protease plasticity Bulut, H; Hattori, SI; Aoki-Ogata, H et al. Sci Rep, DOI://10.1038/s41598-020-65993-z (2020)
- Single-cell ATAC-Seq in human pancreatic islets and deep learning upscaling of rare cells reveals cell-specific type 2 diabetes regulatory signatures Rai, V; Quang, DX; Erdos, MR et al. Mol Metab, DOI://10.1016/j.molmet.2019.12.006 (2020)
- Group testing in mediation analysis Derkach, A; Moore, SC; Boca, SM; Sampson, JN; , Stat Med, DOI://10.1002/sim.8546 (2020)
- Inhibition stabilization is a widespread property of cortical networks Sanzeni, A; Akitake, B; Goldbach, HC; Leedy, CE; Brunel, N; Histed, MH; Elife, DOI://10.7554/eLife.54875 (2020)
- Large-scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease Bandres-Ciga, S; Saez-Atienzar, S; Kim, JJ et al. Acta Neuropathol., DOI://10.1007/s00401-020-02181-3 (2020)
- Sample-weighted semiparametric estimation of cause-specific cumulative risk and incidence using left- or interval-censored data from electronic health records Hyun, N; Katki, HA; Graubard, BI; Stat Med, DOI://10.1002/sim.8544 (2020)
- A New Molecular-Mechanics Model for Simulations of Hydrogen Fluoride in Chemistry and Biology Orabi, EA; Faraldo-Gomez, JD; J Chem Theory Comput, DOI://10.1021/acs.jctc.0c00247 (2020)
- Single-Cell-Derived Primary Rectal Carcinoma Cell Lines Reflect Intratumor Heterogeneity Associated with Treatment Response Braun, R; Anthuber, L; Hirsch, D et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-19-1984 (2020)
- Cotranslational folding cooperativity of contiguous domains of α-spectrin Kemp, G; Nilsson, OB; Tian, P; Best, RB; von Heijne, G; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1909683117 (2020)
- Analysis of Thyroid Hormone Receptor α-Knockout Tadpoles Reveals That the Activation of Cell Cycle Program Is Involved in Thyroid Hormone-Induced Larval Epithelial Cell Death and Adult Intestinal Stem Cell Development During Xenopus tropicalis Metamorphosis Tanizaki, Y; Shibata, Y; Zhang, H; Shi, YB; Thyroid, DOI://10.1089/thy.2020.0022 (2020)
- Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases de Jesus, AA; Hou, Y; Brooks, S et al. J. Clin. Invest., DOI://10.1172/JCI129301 (2020)
- Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery Guardia, CM; Tan, XF; Lian, T et al. Cell Rep, DOI://10.1016/j.celrep.2020.107837 (2020)
- Mutations in FYCO1 identified in families with congenital cataracts Iqbal, H; Khan, SY; Zhou, L et al. Mol. Vis., 1090-0535 (2020)
- Ancient familial Mediterranean fever mutations in human pyrin and resistance to Yersinia pestis Park, YH; Remmers, EF; Lee, W et al. Nat. Immunol., DOI://10.1038/s41590-020-0705-6 (2020)
- Metabolic reprogramming associated with aggressiveness occurs in the G-CIMP-high molecular subtypes of IDH1mut lower grade gliomas Ruiz-Rodado, V; Malta, TM; Seki, T et al. Neuro-oncology, DOI://10.1093/neuonc/noz207 (2020)
- Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer Lin, Y; Nakatochi, M; Hosono, Y et al. Nat Commun, DOI://10.1038/s41467-020-16711-w (2020)
- The genomic and epigenomic evolutionary history of papillary renal cell carcinomas Zhu, B; Poeta, ML; Costantini, M et al. Nat Commun, DOI://10.1038/s41467-020-16546-5 (2020)
- Oral microbial community composition is associated with pancreatic cancer: A case-control study in Iran Vogtmann, E; Han, Y; Caporaso, JG et al. Cancer Med, DOI://10.1002/cam4.2660 (2020)
- True S-cones are concentrated in the ventral mouse retina and wired for color detection in the upper visual field Nadal-Nicolás, FM; Kunze, VP; Ball, JM et al. Elife, DOI://10.7554/eLife.56840 (2020)
- The RNA-binding protein PTBP1 promotes ATPase-dependent dissociation of the RNA helicase UPF1 to protect transcripts from nonsense-mediated mRNA decay Fritz, SE; Ranganathan, S; Wang, CD; Hogg, JR; J. Biol. Chem., DOI://10.1074/jbc.RA120.013824 (2020)
- Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization So, JY; Skrypek, N; Yang, HH et al. Cancer Res., DOI://10.1158/0008-5472.CAN-19-3339 (2020)
- fs(1)A1304 1 Is a 5' UTR Deletion of the Essential Gene small ovary in Drosophila Hammond, M; Gomez, JG; Oliver, B; Kucera, S; Benner, L; MicroPubl Biol, DOI://10.17912/micropub.biology.000246 (2020)
- Activity-dependent tuning of intrinsic excitability in mouse and human neurogliaform cells Chittajallu, R; Auville, K; Mahadevan, V et al. Elife, DOI://10.7554/eLife.57571 (2020)
- eIF1 discriminates against suboptimal initiation sites to prevent excessive uORF translation genome-wide Zhou, F; Zhang, H; Kulkarni, SD; Lorsch, JR; Hinnebusch, AG; RNA, DOI://10.1261/rna.073536.119 (2020)
- An improved pig reference genome sequence to enable pig genetics and genomics research Warr, A; Affara, N; Aken, B et al. Gigascience, DOI://10.1093/gigascience/giaa051 (2020)
- Integrated VASO and perfusion contrast: A new tool for laminar functional MRI Chai, Y; Li, L; Huber, L; Poser, BA; Bandettini, PA; Neuroimage, DOI://10.1016/j.neuroimage.2019.116358 (2020)
- KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage Wolf, G; de Iaco, A; Sun, MA et al. Elife, DOI://10.7554/eLife.56337 (2020)
- Beware (Surprisingly Common) Left-Right Flips in Your MRI Data: An Efficient and Robust Method to Check MRI Dataset Consistency Using AFNI Glen, DR; Taylor, PA; Buchsbaum, BR; Cox, RW; Reynolds, RC; Front Neuroinform, DOI://10.3389/fninf.2020.00018 (2020)
- Cell-Specific Transcriptional Responses to Heat Shock in the Mouse Utricle Epithelium Sadler, E; Ryals, MM; May, LA et al. Front Cell Neurosci, DOI://10.3389/fncel.2020.00123 (2020)
- Tensor image enhancement and optimal multichannel receiver combination analyses for human hyperpolarized 13 C MRSI Chen, HY; Autry, AW; Brender, JR et al. Magn Reson Med, DOI://10.1002/mrm.28328 (2020)
- Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies Gurusamy, D; Henning, AN; Yamamoto, TN et al. Cancer Cell, DOI://10.1016/j.ccell.2020.05.004 (2020)
- The genomic landscape of metastasis in treatment-naive breast cancer models Ross, C; Szczepanek, K; Lee, M et al. PLoS Genet., DOI://10.1371/journal.pgen.1008743 (2020)
- An imputation approach for fitting two-part mixed effects models for longitudinal semi-continuous data Choo-Wosoba, H; Kundu, D; Albert, PS; Stat Methods Med Res, DOI://10.1177/0962280220927720 (2020)
- Variability in the analysis of a single neuroimaging dataset by many teams Botvinik-Nezer, R; Holzmeister, F; Camerer, CF et al. Nature, DOI://10.1038/s41586-020-2314-9 (2020)
- Common genetic susceptibility loci link PFAPA syndrome, Behçet's disease, and recurrent aphthous stomatitis Manthiram, K; Preite, S; Dedeoglu, F et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.2002051117 (2020)
- Metastasis-specific gene expression in autochthonous and allograft mouse mammary tumor models: stratification and identification of targetable signatures Ross, C; Szczepanek, K; Lee, M et al. Mol. Cancer Res., DOI://10.1158/1541-7786.MCR-20-0046 (2020)
- Layer-dependent functional connectivity methods Huber, L; Finn, ES; Chai, Y et al. Prog. Neurobiol., DOI://10.1016/j.pneurobio.2020.101835 (2020)
- Dynamic morphogenesis of a pioneer axon in Drosophila and its regulation by Abl tyrosine kinase Clarke, A; McQueen, PG; Fang, HY et al. Mol. Biol. Cell, DOI://10.1091/mbc.E19-10-0563 (2020)
- The structure of emotional support networks in families affected by Lynch syndrome Marcum, CS; Lea, D; Eliezer, D; Hadley, DW; Koehly, LM Network Science, doi:10.1017/nws.2020.13 (2020)
- Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer Roper, N; Brown, AL; Wei, JS et al. Cell Rep Med, DOI://10.1016/j.xcrm.2020.100007 (2020)
- Ensuring meiotic DNA break formation in the mouse pseudoautosomal region Acquaviva, L; Boekhout, M; Karasu, ME et al. Nature, DOI://10.1038/s41586-020-2327-4 (2020)
- The undiagnosed diseases program: Approach to diagnosis Macnamara, EF; D'Souza, P; , ; Tifft, CJ; , Transl Sci Rare Dis, DOI://10.3233/TRD-190045 (2020)
- DNA methylation loci in placenta associated with birthweight and expression of genes relevant for early development and adult diseases Tekola-Ayele, F; Zeng, X; Ouidir, M et al. Clin Epigenetics, DOI://10.1186/s13148-020-00873-x (2020)
- Atomistic mechanism of transmembrane helix association Domański, J; Sansom, MSP; Stansfeld, PJ; Best, RB; PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1007919 (2020)
- Peptidylarginine Deiminase IV Regulates Breast Cancer Stem Cells via a Novel Tumor Cell-Autonomous Suppressor Role Moshkovich, N; Ochoa, HJ; Tang, B et al. Cancer Res., DOI://10.1158/0008-5472.CAN-19-3018 (2020)
- Discovery, Optimization, and Characterization of ML417: A Novel and Highly Selective D 3 Dopamine Receptor Agonist Moritz, AE; Free, RB; Weiner, WS et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.0c00424 (2020)
- Multiresolution Application of Artificial Intelligence in Digital Pathology for Prediction of Positive Lymph Nodes From Primary Tumors in Bladder Cancer Harmon, SA; Sanford, TH; Brown, GT et al. JCO Clin Cancer Inform, DOI://10.1200/CCI.19.00155 (2020)
- Dynorphin and Enkephalin Opioid Peptides and Transcripts in Spinal Cord and Dorsal Root Ganglion During Peripheral Inflammatory Hyperalgesia and Allodynia Sapio, MR; Iadarola, MJ; Loydpierson, AJ et al. J Pain, DOI://10.1016/j.jpain.2020.01.001 (2020)
- Predicting RNA SHAPE scores with deep learning Bliss, N; Bindewald, E; Shapiro, BA; RNA Biol, DOI://10.1080/15476286.2020.1760534 (2020)
- The Heterogeneity of Anxious Phenotypes: Neural Responses to Errors in Treatment-Seeking Anxious and Behaviorally Inhibited Youths Smith, AR; White, LK; Leibenluft, E et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2019.05.014 (2020)
- Infant behavioral reactivity predicts change in amygdala volume 12 years later Filippi, CA; Sachs, JF; Phillips, D et al. Dev Cogn Neurosci, DOI://10.1016/j.dcn.2020.100776 (2020)
- ORCA/LRWD1 Regulates Homologous Recombination at ALT-Telomeres by Modulating Heterochromatin Organization Hsu, RYC; Lin, YC; Redon, C et al. iScience, DOI://10.1016/j.isci.2020.101038 (2020)
- Trans-ethnic meta-analysis of genome-wide association studies identifies maternal ITPR1 as a novel locus influencing fetal growth during sensitive periods in pregnancy Tekola-Ayele, F; Zhang, C; Wu, J et al. PLoS Genet., DOI://10.1371/journal.pgen.1008747 (2020)
- Synthesis and evaluation of the anti-hepatitis B virus activity of 4'-Azido-thymidine analogs and 4'-Azido-2'-deoxy-5-methylcytidine analogs: structural insights for the development of a novel anti-HBV agent Onitsuka, K; Tokuda, R; Kuwata-Higashi, N et al. Nucleosides Nucleotides Nucleic Acids, DOI://10.1080/15257770.2019.1664749 (2020)
- Plasmodium vivax and Human Hexokinases Share Similar Active Sites but Display Distinct Quaternary Architectures Srivastava, SS; Darling, JE; Suryadi, J; Morris, JC; Drew, ME; Subramaniam, S; IUCrJ, DOI://10.1107/S2052252520002456 (2020)
- Genetic and epigenetic intratumor heterogeneity impacts prognosis of lung adenocarcinoma Hua, X; Zhao, W; Pesatori, AC et al. Nat Commun, DOI://10.1038/s41467-020-16295-5 (2020)
- Dual histone methyl reader ZCWPW1 facilitates repair of meiotic double strand breaks in male mice Mahgoub, M; Paiano, J; Bruno, M et al. Elife, DOI://10.7554/eLife.53360 (2020)
- Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase Palmieri, EM; Gonzalez-Cotto, M; Baseler, WA et al. Nat Commun, DOI://10.1038/s41467-020-14433-7 (2020)
- Fast detection and reduction of local transient artifacts in resting-state fMRI Jo, HJ; Reynolds, RC; Gotts, SJ et al. Comput. Biol. Med., DOI://10.1016/j.compbiomed.2020.103742 (2020)
- Accelerated epigenetic age and cognitive decline among urban-dwelling adults Beydoun, MA; Shaked, D; Tajuddin, SM; Weiss, J; Evans, MK; Zonderman, AB; Neurology, DOI://10.1212/WNL.0000000000008756 (2020)
- Conserved protein Pir2 ARS2 mediates gene repression through cryptic introns in lncRNAs. Thillainadesan, G; Xiao, H; Holla, S et al. Nat Commun, DOI://10.1038/s41467-020-16280-y (2020)
- Patients infected with Mycobacterium africanum versus Mycobacterium tuberculosis possess distinct intestinal microbiota Namasivayam, S; Diarra, B; Diabate, S et al. PLoS Negl Trop Dis, DOI://10.1371/journal.pntd.0008230 (2020)
- Assessment of Genetic Association Between Parkinson Disease and Bipolar Disorder Bandres-Ciga, S; Blauwendraat, C; Singleton, AB; JAMA Neurol, DOI://10.1001/jamaneurol.2020.0248 (2020)
- Dissecting the phenotypic and functional heterogeneity of mouse inflammatory osteoclasts by the expression of Cx3cr1 Madel, MB; Ibáñez, L; Ciucci, T et al. Elife, DOI://10.7554/eLife.54493 (2020)
- Characterization of the development of the mouse cochlear epithelium at the single cell level Kolla, L; Kelly, MC; Mann, ZF et al. Nat Commun, DOI://10.1038/s41467-020-16113-y (2020)
- Whole exome sequencing in patients with Williams-Beuren syndrome followed by disease modeling in mice points to four novel pathways that may modify stenosis risk Parrish, PCR; Liu, D; Knutsen, RH et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddaa093 (2020)
- Medin Oligomer Membrane Pore Formation: A Potential Mechanism of Vascular Dysfunction Younger, S; Jang, H; Davies, HA et al. Biophys. J., DOI://10.1016/j.bpj.2020.04.026 (2020)
- Assessing established BMI variants for a role in nighttime eating behavior in robustly phenotyped Southwestern American Indians Köroğlu, Ç; Gluck, ME; Traurig, M et al. Eur J Clin Nutr, DOI://10.1038/s41430-020-0654-z (2020)
- Distinct gene expression patterns in vector-residing Leishmania infantum identify parasite stage-enriched markers Coutinho-Abreu, IV; Serafim, TD; Meneses, C; Kamhawi, S; Oliveira, F; Valenzuela, JG; PLoS Negl Trop Dis, DOI://10.1371/journal.pntd.0008014 (2020)
- Somatic SMAD3-activating mutations cause melorheostosis by up-regulating the TGF-β/SMAD pathway Kang, H; Jha, S; Ivovic, A et al. J. Exp. Med., DOI://10.1084/jem.20191499 (2020)
- Genome-wide association studies of the self-rating of effects of ethanol (SRE) Lai, D; Wetherill, L; Kapoor, M et al. Addict Biol, DOI://10.1111/adb.12800 (2020)
- Dimensionality, information and learning in prefrontal cortex Bartolo, R; Saunders, RC; Mitz, AR; Averbeck, BB; PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1007514 (2020)
- Ductal Carcinoma In Situ Progression in Dog Model of Breast Cancer Mohammed, SI; Utturkar, S; Lee, M et al. Cancers (Basel), DOI://10.3390/cancers12020418 (2020)
- Amelotin is expressed in retinal pigment epithelium and localizes to hydroxyapatite deposits in dry age-related macular degeneration Rajapakse, D; Peterson, K; Mishra, S et al. Transl Res, DOI://10.1016/j.trsl.2020.02.007 (2020)
- Creating 2D Occupancy Plots Using plot2DO Beati, P; Chereji, RV; Methods Mol. Biol., DOI://10.1007/978-1-0716-0301-7_5 (2020)
- Haplotype-resolved genomes provide insights into structural variation and gene content in Angus and Brahman cattle Low, WY; Tearle, R; Liu, R et al. Nat Commun, DOI://10.1038/s41467-020-15848-y (2020)
- Quantitative Proteomics of All 14 Renal Tubule Segments in Rat Limbutara, K; Chou, CL; Knepper, MA; J. Am. Soc. Nephrol., DOI://10.1681/ASN.2020010071 (2020)
- Id1 and Id3 Maintain Steady-State Hematopoiesis by Promoting Sinusoidal Endothelial Cell Survival and Regeneration Gadomski, S; Singh, SK; Singh, S et al. Cell Rep, DOI://10.1016/j.celrep.2020.107572 (2020)
- Genetic model of MS severity predicts future accumulation of disability Jackson, KC; Sun, K; Barbour, C et al. Ann. Hum. Genet., DOI://10.1111/ahg.12342 (2020)
- Stress keratin 17 enhances papillomavirus infection-induced disease by downregulating T cell recruitment Wang, W; Uberoi, A; Spurgeon, M et al. PLoS Pathog., DOI://10.1371/journal.ppat.1008206 (2020)
- Survey of ribose ring pucker of signaling nucleosides and nucleotides Salmaso, V; Jacobson, KA; Nucleosides Nucleotides Nucleic Acids, DOI://10.1080/15257770.2019.1658115 (2020)
- The interdependence of mammary-specific super-enhancers and their native promoters facilitates gene activation during pregnancy Zeng, X; Lee, HK; Wang, C; Achikeh, P; Liu, C; Hennighausen, L; Exp. Mol. Med., DOI://10.1038/s12276-020-0425-x (2020)
- Truncated (N)-Methanocarba Nucleosides as Partial Agonists at Mouse and Human A 3 Adenosine Receptors: Affinity Enhancement by N6-(2-Phenylethyl) Substitution Tosh, DK; Salmaso, V; Rao, H et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.0c00235 (2020)
- Expression of the muscle-associated gene MYF6 in hairy cell leukemia Arons, E; Zhou, H; Sokolsky, M et al. PLoS ONE, DOI://10.1371/journal.pone.0227586 (2020)
- Genome-wide Profiling Identifies DNA Methylation Signatures of Aging in Rod Photoreceptors Associated with Alterations in Energy Metabolism Corso-Díaz, X; Gentry, J; Rebernick, R et al. Cell Rep, DOI://10.1016/j.celrep.2020.107525 (2020)
- Protonation state of the selectivity filter of bacterial voltage-gated sodium channels is modulated by ions Damjanovic, A; Chen, AY; Rosenberg, RL; Roe, DR; Wu, X; Brooks, BR; , Proteins, DOI://10.1002/prot.25831 (2020)
- Sperm Head-Tail Linkage Requires Restriction of Pericentriolar Material to the Proximal Centriole End Galletta, BJ; Ortega, JM; Smith, SL et al. Dev. Cell, DOI://10.1016/j.devcel.2020.02.006 (2020)
- Prefrontal Cortex Predicts State Switches during Reversal Learning Bartolo, R; Averbeck, BB; Neuron, DOI://10.1016/j.neuron.2020.03.024 (2020)
- Phase-plate cryo-EM structure of the Widom 601 CENP-A nucleosome core particle reveals differential flexibility of the DNA ends Boopathi, R; Danev, R; Khoshouei, M et al. Nucleic Acids Res., DOI://10.1093/nar/gkaa246 (2020)
- How mouse RAG recombinase avoids DNA transposition Chen, X; Cui, Y; Wang, H; Zhou, ZH; Gellert, M; Yang, W; Nat. Struct. Mol. Biol., DOI://10.1038/s41594-019-0366-z (2020)
- Intrinsic connections between thalamic sub-regions and the lateral prefrontal cortex are differentially impacted by acute methylphenidate Gorka, AX; Lago, TR; Balderston, N et al. Psychopharmacology (Berl.), DOI://10.1007/s00213-020-05505-z (2020)
- 7-Deaza-7-fluoro modification confers on 4'-cyano-nucleosides potent activity against entecavir/adefovir-resistant HBV variants and favorable safety Hayashi, S; Higashi-Kuwata, N; Das, D et al. Antiviral Res., DOI://10.1016/j.antiviral.2020.104744 (2020)
- Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas Hickman, AB; Kailasan, S; Genzor, P; Haase, AD; Dyda, F; Elife, DOI://10.7554/eLife.50004 (2020)
- AGO2 Mediates MYC mRNA Stability in Hepatocellular Carcinoma Zhang, K; Pomyen, Y; Barry, AE et al. Mol. Cancer Res., DOI://10.1158/1541-7786.MCR-19-0805 (2020)
- Systematic integration of GATA transcription factors and epigenomes via IDEAS paints the regulatory landscape of hematopoietic cells Hardison, RC; Zhang, Y; Keller, CA et al. IUBMB Life, DOI://10.1002/iub.2195 (2020)
- Confidence intervals for the difference between two relative risks Sampson, JN; Gail, MH; Stat Methods Med Res, DOI://10.1177/0962280220915737 (2020)
- High density of unrepaired genomic ribonucleotides leads to Topoisomerase 1-mediated severe growth defects in absence of ribonucleotide reductase Cerritelli, SM; Iranzo, J; Sharma, S et al. Nucleic Acids Res., DOI://10.1093/nar/gkaa103 (2020)
- Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression Farmer, CA; Gilbert, JR; Moaddel, R et al. Neuropsychopharmacology, DOI://10.1038/s41386-020-0663-6 (2020)
- Erasure machine: Inverse Ising inference from reweighting of observation frequencies Jo, J; Hoang, DT; Periwal, V; , Phys Rev E, DOI://10.1103/PhysRevE.101.032107 (2020)
- Skin Microbiota Perturbations Are Distinct and Disease Severity-Dependent in Hidradenitis Suppurativa Naik, HB; Jo, JH; Paul, M; Kong, HH; , J. Invest. Dermatol., DOI://10.1016/j.jid.2019.08.445 (2020)
- Investigation of the Influence of Thyroid Location on Iodine-131 S Values Yeom, YS; Villoing, D; Greenstein, N et al. Radiat Prot Dosimetry, DOI://10.1093/rpd/ncaa027 (2020)
- A Probabilistic Classification Tool for Genetic Subtypes of Diffuse Large B Cell Lymphoma with Therapeutic Implications Wright, GW; Huang, DW; Phelan, JD et al. Cancer Cell, DOI://10.1016/j.ccell.2020.03.015 (2020)
- In vivo functional analysis of non-conserved human lncRNAs associated with cardiometabolic traits Ruan, X; Li, P; Chen, Y et al. Nat Commun, DOI://10.1038/s41467-019-13688-z (2020)
- A hidden Markov modeling approach for identifying tumor subclones in next-generation sequencing studies Choo-Wosoba, H; Albert, PS; Zhu, B; Biostatistics, DOI://10.1093/biostatistics/kxaa013 (2020)
- Quantum chemical predictions of water-octanol partition coefficients applied to the SAMPL6 logP blind challenge Jones, MR; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-020-00286-1 (2020)
- Multi-phase Boltzmann weighting: accounting for local inhomogeneity in molecular simulations of water-octanol partition coefficients in the SAMPL6 challenge Krämer, A; Hudson, PS; Jones, MR; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-020-00285-2 (2020)
- Feedback inhibition and its control in an insect olfactory circuit Ray, S; Aldworth, ZN; Stopfer, MA; Elife, DOI://10.7554/eLife.53281 (2020)
- Interpretation of HDX Data by Maximum-Entropy Reweighting of Simulated Structural Ensembles Bradshaw, RT; Marinelli, F; Faraldo-Gómez, JD; Forrest, LR; Biophys. J., DOI://10.1016/j.bpj.2020.02.005 (2020)
- A Shared Regulatory Element Controls the Initiation of Tcf7 Expression During Early T Cell and Innate Lymphoid Cell Developments Harly, C; Kenney, D; Wang, Y et al. Front Immunol, DOI://10.3389/fimmu.2020.00470 (2020)
- Idiosynchrony: From shared responses to individual differences during naturalistic neuroimaging Finn, ES; Glerean, E; Khojandi, AY et al. Neuroimage, DOI://10.1016/j.neuroimage.2020.116828 (2020)
- The quaternary assembly of KRas4B with Raf-1 at the membrane Jang, H; Zhang, M; Nussinov, R; Comput Struct Biotechnol J, DOI://10.1016/j.csbj.2020.03.018 (2020)
- Continuous chromosome-scale haplotypes assembled from a single interspecies F1 hybrid of yak and cattle Rice, ES; Koren, S; Rhie, A et al. Gigascience, DOI://10.1093/gigascience/giaa029 (2020)
- Structures of AAA protein translocase Bcs1 suggest translocation mechanism of a folded protein Tang, WK; Borgnia, MJ; Hsu, AL et al. Nat. Struct. Mol. Biol., DOI://10.1038/s41594-020-0373-0 (2020)
- Predisposition to hematologic malignancies in patients with xeroderma pigmentosum Oetjen, KA; Levoska, MA; Tamura, D et al. Haematologica, DOI://10.3324/haematol.2019.223370 (2020)
- Levels of early-childhood behavioral inhibition predict distinct neurodevelopmental pathways to pediatric anxiety Abend, R; Swetlitz, C; White, LK et al. Psychol Med, DOI://10.1017/S0033291718003999 (2020)
- Structure elucidation and absolute configuration of metabolites from the soil-derived fungus Dictyosporium digitatum using spectroscopic and computational methods Tran, TD; Wilson, BAP; Henrich, CJ et al. Phytochemistry, DOI://10.1016/j.phytochem.2020.112278 (2020)
- Differential DNA Methylation in Placenta Associated With Maternal Blood Pressure During Pregnancy Workalemahu, T; Ouidir, M; Shrestha, D; Wu, J; Grantz, KL; Tekola-Ayele, F; Hypertension, DOI://10.1161/HYPERTENSIONAHA.119.14509 (2020)
- Family-based exome sequencing identifies rare coding variants in age-related macular degeneration Ratnapriya, R; Acar, İE; Geerlings, MJ et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddaa057 (2020)
- Next-generation sequencing of the intrahepatic antibody repertoire delineates a unique B-cell response in HBV-associated acute liver failure Chen, Z; Shen, CH; Engle, RE et al. J. Viral Hepat., DOI://10.1111/jvh.13290 (2020)
- CRISPR-Cas9/phosphoproteomics identifies multiple noncanonical targets of myosin light chain kinase Isobe, K; Raghuram, V; Krishnan, L; Chou, CL; Yang, CR; Knepper, MA; Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00431.2019 (2020)
- Genotype-phenotype association and variant characterization in Diamond-Blackfan anemia caused by pathogenic variants in RPL35A Gianferante, DM; Wlodarski, MW; Atsidaftos, E et al. Haematologica, DOI://10.3324/haematol.2020.246629 (2020)
- Comprehensive RNA-Seq analysis of notochord-enriched genes induced during Xenopus tropicalis tail resorption Nakajima, K; Tanizaki, Y; Luu, N; Zhang, H; Shi, YB; Gen. Comp. Endocrinol., DOI://10.1016/j.ygcen.2019.113349 (2020)
- Retinal Organoids derived from hiPSCs of an AIPL1-LCA Patient Maintain Cytoarchitecture despite Reduced levels of Mutant AIPL1 Lukovic, D; Artero Castro, A; Kaya, KD et al. Sci Rep, DOI://10.1038/s41598-020-62047-2 (2020)
- mTORC2/Rac1 Pathway Predisposes Cancer Aggressiveness in IDH1-Mutated Glioma Liu, Y; Lu, Y; Li, A et al. Cancers (Basel), DOI://10.3390/cancers12040787 (2020)
- Gene co-expression networks are associated with obesity-related traits in kidney transplant recipients Jaime-Lara, RB; Roy, A; Wang, Y; Stanfill, A; Cashion, AK; Joseph, PV; BMC Med Genomics, DOI://10.1186/s12920-020-0702-5 (2020)
- RNAseq expression patterns of canine invasive urothelial carcinoma reveal two distinct tumor clusters and shared regions of dysregulation with human bladder tumors Parker, HG; Dhawan, D; Harris, AC et al. BMC Cancer, DOI://10.1186/s12885-020-06737-0 (2020)
- Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress Murai, J; Zhang, H; Pongor, L et al. Cell Rep, DOI://10.1016/j.celrep.2020.02.117 (2020)
- Suppressing proteasome mediated processing of topoisomerase II DNA-protein complexes preserves genome integrity Sciascia, N; Wu, W; Zong, D et al. Elife, DOI://10.7554/eLife.53447 (2020)
- Understanding the Cause and Consequence of Tumor Heterogeneity Khatib, S; Pomyen, Y; Dang, H; Wang, XW; , Trends Cancer, DOI://10.1016/j.trecan.2020.01.010 (2020)
- YAP1/TAZ-TEAD transcriptional networks maintain skin homeostasis by regulating cell proliferation and limiting KLF4 activity Yuan, Y; Park, J; Feng, A et al. Nat Commun, DOI://10.1038/s41467-020-15301-0 (2020)
- De novo assembly of the cattle reference genome with single-molecule sequencing Rosen, BD; Bickhart, DM; Schnabel, RD et al. Gigascience, DOI://10.1093/gigascience/giaa021 (2020)
- Association of polygenic score for major depression with response to lithium in patients with bipolar disorder Amare, AT; Schubert, KO; Hou, L et al. Mol. Psychiatry, DOI://10.1038/s41380-020-0689-5 (2020)
- Stylized versus voxel phantoms: a juxtaposition of organ depth distributions Griffin, KT; Cuthbert, TA; Dewji, SA; Lee, C; Phys Med Biol, DOI://10.1088/1361-6560/ab7686 (2020)
- Tautomer Database: A Comprehensive Resource for Tautomerism Analyses Dhaked, DK; Guasch, L; Nicklaus, MC; J Chem Inf Model, DOI://10.1021/acs.jcim.9b01156 (2020)
- Toward a Comprehensive Treatment of Tautomerism in Chemoinformatics Including in InChI V2 Dhaked, DK; Ihlenfeldt, WD; Patel, H; Delannée, V; Nicklaus, MC; J Chem Inf Model, DOI://10.1021/acs.jcim.9b01080 (2020)
- Multiple testing correction overcontrasts for brain imaging Alberton, BAV; Nichols, TE; Gamba, HR; Winkler, AM; Neuroimage, DOI://10.1016/j.neuroimage.2020.116760 (2020)
- Prediction of stress and drug craving ninety minutes in the future with passively collected GPS data Epstein, DH; Tyburski, M; Kowalczyk, WJ et al. NPJ Digit Med, DOI://10.1038/s41746-020-0234-6 (2020)
- Analysis of DNA methylation patterns in the tumor immune microenvironment of metastatic melanoma Mitra, S; Lauss, M; Cabrita, R et al. Mol Oncol, DOI://10.1002/1878-0261.12663 (2020)
- Distinct inactive conformations of the dopamine D2 and D3 receptors correspond to different extents of inverse agonism Lane, JR; Abramyan, AM; Adhikari, P et al. Elife, DOI://10.7554/eLife.52189 (2020)
- Modulating the Stiffness of the Myosin VI Single α-Helical Domain Barnes, CA; Shen, Y; Ying, J; Bax, A; Biophys. J., DOI://10.1016/j.bpj.2020.01.003 (2020)
- Interplay between DNA damage repair and apoptosis shapes cancer evolution through aneuploidy and microsatellite instability Auslander, N; Wolf, YI; Koonin, EV; Nat Commun, DOI://10.1038/s41467-020-15094-2 (2020)
- Outcome-related signatures identified by Whole Transcriptome Sequencing of Resectable Stage III/IV Melanoma Evaluated After Starting Hu14.18-IL2 Yang, RK; Kuznetsov, IB; Ranheim, EA et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-19-3294 (2020)
- Longitudinal Positron Emission Tomography of Dopamine Synthesis in Subjects with GBA1 Mutations Lopez, G; Eisenberg, DP; Gregory, MD et al. Ann. Neurol., DOI://10.1002/ana.25692 (2020)
- Combining fMRI during resting state and an attention bias task in children Harrewijn, A; Abend, R; Linke, J et al. Neuroimage, DOI://10.1016/j.neuroimage.2019.116301 (2020)
- Sex-biased trajectories of amygdalo-hippocampal morphology change over human development Fish, AM; Nadig, A; Seidlitz, J et al. Neuroimage, DOI://10.1016/j.neuroimage.2019.116122 (2020)
- Stem Cell-Derived Endothelial Cell Model that Responds to Tobacco Smoke Like Primary Endothelial Cells Chu, PH; Chen, G; Kuo, D et al. Chem. Res. Toxicol., DOI://10.1021/acs.chemrestox.9b00363 (2020)
- Multiple lipid binding sites determine the affinity of PH domains for phosphoinositide-containing membranes Yamamoto, E; Domanski, J; Naughton, FB et al. Sci Adv, DOI://10.1126/sciadv.aay5736 (2020)
- Tick-Borne Encephalitis Virus Infection Alters the Sialome of Ixodes ricinus Ticks During the Earliest Stages of Feeding Hart, CE; Ribeiro, JM; Kazimirova, M; Thangamani, S; Front Cell Infect Microbiol, DOI://10.3389/fcimb.2020.00041 (2020)
- Low-frequency parietal repetitive transcranial magnetic stimulation reduces fear and anxiety Balderston, NL; Beydler, EM; Goodwin, M et al. Transl Psychiatry, DOI://10.1038/s41398-020-0751-8 (2020)
- Molecular and cellular determinants of motor asymmetry in zebrafish Horstick, EJ; Bayleyen, Y; Burgess, HA; Nat Commun, DOI://10.1038/s41467-020-14965-y (2020)
- C. elegans pronuclei fuse after fertilization through a novel membrane structure Rahman, M; Chang, IY; Harned, A et al. J. Cell Biol., DOI://10.1083/jcb.201909137 (2020)
- Measurement of differential chromatin interactions with absolute quantification of architecture (AQuA-HiChIP) Gryder, BE; Khan, J; Stanton, BZ; Nat Protoc, DOI://10.1038/s41596-019-0285-9 (2020)
- Characterizing Adult Cochlear Supporting Cell Transcriptional Diversity Using Single-Cell RNA-Seq: Validation in the Adult Mouse and Translational Implications for the Adult Human Cochlea Hoa, M; Olszewski, R; Li, X et al. Front Mol Neurosci, DOI://10.3389/fnmol.2020.00013 (2020)
- Oncogenic K-Ras4B Dimerization Enhances Downstream Mitogen-activated Protein Kinase Signaling Muratcioglu, S; Aydin, C; Odabasi, E et al. J. Mol. Biol., DOI://10.1016/j.jmb.2020.01.002 (2020)
- Modeling repeated labor curves in consecutive pregnancies: Individualized prediction of labor progression from previous pregnancy data Buhule, OD; Choo-Wosoba, H; Albert, PS; Stat Med, DOI://10.1002/sim.8462 (2020)
- Serial evaluation of CD19 surface expression in pediatric B-cell malignancies following CD19-targeted therapy Libert, D; Yuan, CM; Masih, KE et al. Leukemia, DOI://10.1038/s41375-020-0760-x (2020)
- Integrative analysis suggests cell type-specific decoding of NF-κB dynamics Martin, EW; Pacholewska, A; Patel, H; Dashora, H; Sung, MH; Sci Signal, DOI://10.1126/scisignal.aax7195 (2020)
- Dense Transposon Integration Reveals Essential Cleavage and Polyadenylation Factors Promote Heterochromatin Formation Lee, SY; Hung, S; Esnault, C et al. Cell Rep, DOI://10.1016/j.celrep.2020.01.094 (2020)
- Low Serum Insulinlike Growth Factor II Levels Correlate with High BMI in American Indian Adults Muller, YL; Hanson, RL; Mahkee, D et al. Obesity (Silver Spring), DOI://10.1002/oby.22741 (2020)
- CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG Liu, Z; Zhang, X; Lei, H et al. Nat Commun, DOI://10.1038/s41467-020-14684-4 (2020)
- A case report of multiple primary prostate tumors with differential drug sensitivity Wilkinson, S; Harmon, SA; Terrigino, NT et al. Nat Commun, DOI://10.1038/s41467-020-14657-7 (2020)
- A resource for the detailed 3D mapping of white matter pathways in the marmoset brain Liu, C; Ye, FQ; Newman, JD et al. Nat. Neurosci., DOI://10.1038/s41593-019-0575-0 (2020)
- The Pharmacopea within Triatomine Salivary Glands Santiago, PB; de Araújo, CN; Charneau, S et al. Trends Parasitol., DOI://10.1016/j.pt.2019.12.014 (2020)
- MY-5445, a phosphodiesterase type 5 inhibitor, resensitizes ABCG2-overexpressing multidrug-resistant cancer cells to cytotoxic anticancer drugs Wu, CP; Lusvarghi, S; Tseng, PJ et al. Am J Cancer Res, 2156-6976 (2020)
- The Glu102 mutation disrupts higher-order oligomerization of the sigma 1 receptor Abramyan, AM; Yano, H; Xu, M et al. Comput Struct Biotechnol J, DOI://10.1016/j.csbj.2019.12.012 (2020)
- High-Affinity Interactions of the nSH3/cSH3 Domains of Grb2 with the C-Terminal Proline-Rich Domain of SOS1 Liao, TJ; Jang, H; Nussinov, R; Fushman, D; J. Am. Chem. Soc., DOI://10.1021/jacs.9b10710 (2020)
- Placental DNA methylation changes associated with maternal prepregnancy BMI and gestational weight gain Shrestha, D; Ouidir, M; Workalemahu, T; Zeng, X; Tekola-Ayele, F; Int J Obes (Lond), DOI://10.1038/s41366-020-0546-2 (2020)
- Refining genome-wide associated loci for serum uric acid in individuals with African ancestry Chen, G; Shriner, D; Doumatey, AP et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddz272 (2020)
- A customizable deep learning model for nosocomial risk prediction from critical care notes with indirect supervision Goodwin, TR; Demner-Fushman, D; J Am Med Inform Assoc, DOI://10.1093/jamia/ocaa004 (2020)
- Transcriptional profiling and physiological roles of Aedes aegypti spermathecal-related genes Pascini, TV; Ramalho-Ortigão, M; Ribeiro, JM; Jacobs-Lorena, M; Martins, GF; BMC Genomics, DOI://10.1186/s12864-020-6543-y (2020)
- Author Correction: Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans Mitchell, KA; Nichols, N; Tang, W et al. Nat Commun, DOI://10.1038/s41467-020-14448-0 (2020)
- Comprehensive Transcriptome Profiling of Cryptic CBFA2T3-GLIS2 Fusion-Positive AML Defines Novel Therapeutic Options: A COG and TARGET Pediatric AML Study Smith, JL; Ries, RE; Hylkema, T et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-19-1800 (2020)
- TCR Repertoires of Thymic Conventional and Regulatory T Cells: Identification and Characterization of Both Unique and Shared TCR Sequences Ko, A; Watanabe, M; Nguyen, T et al. J. Immunol., DOI://10.4049/jimmunol.1901006 (2020)
- Whole Exome Sequencing of Highly Aggregated Lung Cancer Families Reveals Linked Loci for Increased Cancer Risk on Chromosomes 12q, 7p, and 4q Musolf, AM; Moiz, BA; Sun, H et al. Cancer Epidemiol. Biomarkers Prev., DOI://10.1158/1055-9965.EPI-19-0887 (2020)
- Evaluating global brain connectivity as an imaging marker for depression: influence of preprocessing strategies and placebo-controlled ketamine treatment Kraus, C; Mkrtchian, A; Kadriu, B; Nugent, AC; Zarate, CA; Evans, JW; Neuropsychopharmacology, DOI://10.1038/s41386-020-0624-0 (2020)
- CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention Pugacheva, EM; Kubo, N; Loukinov, D et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1911708117 (2020)
- Discovery of several thousand highly diverse circular DNA viruses Tisza, MJ; Pastrana, DV; Welch, NL et al. Elife, DOI://10.7554/eLife.51971 (2020)
- Sub-millimeter fMRI reveals multiple topographical digit representations that form action maps in human motor cortex Huber, L; Finn, ES; Handwerker, DA et al. Neuroimage, DOI://10.1016/j.neuroimage.2019.116463 (2020)
- Truncated tetrahedral RNA nanostructures exhibit enhanced features for delivery of RNAi substrates Zakrevsky, P; Kasprzak, WK; Heinz, WF et al. Nanoscale, DOI://10.1039/c9nr08197f (2020)
- SAMPL6 logP challenge: machine learning and quantum mechanical approaches Patel, P; Kuntz, DM; Jones, MR; Brooks, BR; Wilson, AK; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-020-00287-0 (2020)
- A deep learning approach for the blind logP prediction in SAMPL6 challenge Prasad, S; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-020-00292-3 (2020)
- Whole Genome Sequence-Based Haplotypes Reveal a Single Origin of the 1393 Bp HBB Deletion Wang, X; Xu, JZ; Conrey, A et al. J. Med. Genet., DOI://10.1136/jmedgenet-2019-106698 (2020)
- Complete Genome Sequence of Myophage Ec_Makalu_002, Which Infects Uropathogenic Escherichia coli Dhungana, G; Malla, R; Rajaure, M; Adhya, S; Microbiol Resour Announc, DOI://10.1128/MRA.01530-19 (2020)
- A dual apolipoprotein C-II mimetic-apolipoprotein C-III antagonist peptide lowers plasma triglycerides Wolska, A; Lo, L; Sviridov, DO et al. Sci Transl Med, DOI://10.1126/scitranslmed.aaw7905 (2020)
- Characterization of Specific Ion Effects on PI(4,5)P 2 Clustering: Molecular Dynamics Simulations and Graph-Theoretic Analysis Han, K; Gericke, A; Pastor, RW; J Phys Chem B, DOI://10.1021/acs.jpcb.9b10951 (2020)
- In search of genetic factors predisposing to familial hairy cell leukemia (HCL): exome-sequencing of four multiplex HCL pedigrees Pemov, A; Pathak, A; Jones, SJ et al. Leukemia, DOI://10.1038/s41375-019-0702-7 (2020)
- ABC-transporter upregulation mediates resistance to the CDK7 inhibitors THZ1 and ICEC0942 Sava, GP; Fan, H; Fisher, RA et al. Oncogene, DOI://10.1038/s41388-019-1008-y (2020)
- Abl Signaling Directs Growth of a Pioneer Axon in Drosophila by Shaping the Intrinsic Fluctuations of Actin Clarke, A; McQueen, PG; Fang, HY et al. Mol. Biol. Cell, DOI://10.1091/mbc.E19-10-0564 (2020)
- Information-limiting correlations in large neural populations Bartolo, R; Saunders, RC; Mitz, AR; Averbeck, BB; J. Neurosci., DOI://10.1523/JNEUROSCI.2072-19.2019 (2020)
- Cytosine base editor 4 but not adenine base editor generates off-target mutations in mouse embryos Lee, HK; Smith, HE; Liu, C; Willi, M; Hennighausen, L; Commun Biol, DOI://10.1038/s42003-019-0745-3 (2020)
- A Transcriptome-Wide Association Study (TWAS) Identifies Novel Candidate Susceptibility Genes for Pancreatic Cancer Zhong, J; Jermusyk, A; Wu, L et al. J. Natl. Cancer Inst., DOI://10.1093/jnci/djz246 (2020)
- Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease Lalaoui, N; Boyden, SE; Oda, H et al. Nature, DOI://10.1038/s41586-019-1828-5 (2020)
- Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation Di Gioia, M; Spreafico, R; Springstead, JR et al. Nat. Immunol., DOI://10.1038/s41590-019-0539-2 (2020)
2019 (520 papers)
- Emerging consensus on the mechanism of polyspecific substrate recognition by the multidrug transporter P-glycoprotein Xia, D; Zhou, F; Esser, L; , Cancer Drug Resist, DOI://10.20517/cdr.2019.22 (2019)
- Renal-Tubule Epithelial Cell Nomenclature for Single-Cell RNA-Sequencing Studies Chen, L; Clark, JZ; Nelson, JW et al. J Am Soc Nephrol, DOI://10.1681/ASN.2019040415 (2019)
- Probing the Structural Organization of Virions and Genomic Ribonucleoprotein Complexes from Type B Influenza Virus by Cryo-electron Microscopy Gulati, NM; Gallagher, JR; McCraw, DM; Harris, AK; , Microsc Microanal, DOI://10.1017/S1431927619007244 (2019)
- A novel HIV-1 protease inhibitor, GRL-044, has potent activity against various HIV-1s with an extremely high genetic barrier to the emergence of HIV-1 drug resistance Aoki, M; Chang, SB; Das, D et al. Glob Health Med, DOI://10.35772/ghm.2019.01003 (2019)
- MAIT cells are imprinted by the microbiota in early life and promote tissue repair Constantinides, MG; Link, VM; Tamoutounour, S et al. Science, DOI://10.1126/science.aax6624 (2019)
- Amphetamines signal through intracellular TAAR1 receptors coupled to Gα13 and GαS in discrete subcellular domains Underhill, SM; Hullihen, PD; Chen, J et al. Mol. Psychiatry, DOI://10.1038/s41380-019-0469-2 (2019)
- GATA3-Controlled Nucleosome Eviction Drives MYC Enhancer Activity in T-cell Development and Leukemia Belver, L; Yang, AY; Albero, R et al. Cancer Discov, DOI://10.1158/2159-8290.CD-19-0471 (2019)
- Sptlc1 is essential for myeloid differentiation and hematopoietic homeostasis Parthibane, V; Acharya, D; Srideshikan, SM et al. Blood Adv, DOI://10.1182/bloodadvances.2019000729 (2019)
- Genome-Wide Association Study in Irradiated Childhood Cancer Survivors Identifies HTR2A for Subsequent Basal Cell Carcinoma Sapkota, Y; Turcotte, LM; Ehrhardt, MJ et al. J. Invest. Dermatol., DOI://10.1016/j.jid.2019.02.029 (2019)
- Mapping histone modifications in low cell number and single cells using antibody-guided chromatin tagmentation (ACT-seq) Carter, B; Ku, WL; Kang, JY et al. Nat Commun, DOI://10.1038/s41467-019-11559-1 (2019)
- Cryo-EM reveals active site coordination within a multienzyme pre-rRNA processing complex Pillon, MC; Hsu, AL; Krahn, JM et al. Nat. Struct. Mol. Biol., DOI://10.1038/s41594-019-0289-8 (2019)
- Beyond Synthetic Lethality: Charting the Landscape of Pairwise Gene Expression States Associated with Survival in Cancer Magen, A; Das Sahu, A; Lee, JS et al. Cell Rep, DOI://10.1016/j.celrep.2019.06.067 (2019)
- ATP-dependent thermostabilization of human P-glycoprotein (ABCB1) is blocked by modulators Lusvarghi, S; Ambudkar, SV; , Biochem. J., DOI://10.1042/BCJ20190736 (2019)
- Organ Doses from Chest Radiographs in Tuberculosis Patients in Canada and Their Uncertainties in Periods from 1930 to 1969 Kocher, DC; Apostoaei, AI; Thomas, BA; Borrego, D; Lee, C; Zablotska, LB; , Health Phys, DOI://10.1097/HP.0000000000001171 (2019)
- Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals Mandaviya, PR; Joehanes, R; Brody, J et al. Am. J. Clin. Nutr., DOI://10.1093/ajcn/nqz031 (2019)
- PARP1 inhibition alleviates injury in ARH3-deficient mice and human cells Mashimo, M; Bu, X; Aoyama, K et al. JCI Insight, DOI://10.1172/jci.insight.124519 (2019)
- Placental malaria vaccine candidate antigen VAR2CSA displays atypical domain architecture in some Plasmodium falciparum strains Doritchamou, JYA; Morrison, R; Renn, JP et al. Commun Biol, DOI://10.1038/s42003-019-0704-z (2019)
- The Selective Class IIa Histone Deacetylase Inhibitor TMP195 Resensitizes ABCB1- and ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Cytotoxic Anticancer Drugs Wu, CP; Lusvarghi, S; Wang, JC et al. Int J Mol Sci, DOI://10.3390/ijms21010238 (2019)
- Assessment of APOE in atypical parkinsonism syndromes Sabir, MS; Blauwendraat, C; Ahmed, S et al. Neurobiol. Dis., DOI://10.1016/j.nbd.2019.02.016 (2019)
- SLC35A2-CDG: Functional characterization, expanded molecular, clinical, and biochemical phenotypes of 30 unreported Individuals Ng, BG; Sosicka, P; Agadi, S et al. Hum. Mutat., DOI://10.1002/humu.23731 (2019)
- Association between epigenetic age acceleration and depressive symptoms in a prospective cohort study of urban-dwelling adults Beydoun, MA; Hossain, S; Chitrala, KN et al. J Affect Disord, DOI://10.1016/j.jad.2019.06.032 (2019)
- Time-lapse Live Imaging and Quantification of Fast Dendritic Branch Dynamics in Developing Drosophila Neurons Sheng, C; Javed, U; Rosenthal, J; Yin, J; Qin, B; Yuan, Q; J Vis Exp, DOI://10.3791/60287 (2019)
- The Genetic Architecture of Parkinson Disease in Spain: Characterizing Population-Specific Risk, Differential Haplotype Structures, and Providing Etiologic Insight Bandres-Ciga, S; Ahmed, S; Sabir, MS et al. Mov. Disord., DOI://10.1002/mds.27864 (2019)
- Anoctamin 8 tethers endoplasmic reticulum and plasma membrane for assembly of Ca2+ signaling complexes at the ER/PM compartment Jha, A; Chung, WY; Vachel, L et al. EMBO J, DOI://10.15252/embj.2018101452 (2019)
- Gene signature predictive of hepatocellular carcinoma patient response to transarterial chemoembolization Fako, V; Martin, SP; Pomyen, Y et al. Int. J. Biol. Sci., DOI://10.7150/ijbs.39534 (2019)
- Assessment of the Association of D2 Dopamine Receptor Gene and Reported Allele Frequencies With Alcohol Use Disorders: A Systematic Review and Meta-analysis Jung, Y; Montel, RA; Shen, PH; Mash, DC; Goldman, D; JAMA Netw Open, DOI://10.1001/jamanetworkopen.2019.14940 (2019)
- Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies Nalls, MA; Blauwendraat, C; Vallerga, CL et al. Lancet Neurol, DOI://10.1016/S1474-4422(19)30320-5 (2019)
- Resistin-like Molecule α Provides Vitamin-A-Dependent Antimicrobial Protection in the Skin Harris, TA; Gattu, S; Propheter, DC et al. Cell Host Microbe, DOI://10.1016/j.chom.2019.04.004 (2019)
- Complementary Task Structure Representations in Hippocampus and Orbitofrontal Cortex during an Odor Sequence Task Zhou, J; Montesinos-Cartagena, M; Wikenheiser, AM; Gardner, MPH; Niv, Y; Schoenbaum, G; Curr. Biol., DOI://10.1016/j.cub.2019.08.040 (2019)
- Negative-Stain Transmission Electron Microscopy of Molecular Complexes for Image Analysis by 2D Class Averaging Gallagher, JR; Kim, AJ; Gulati, NM; Harris, AK; Curr Protoc Microbiol, DOI://10.1002/cpmc.90 (2019)
- NAA10 polyadenylation signal variants cause syndromic microphthalmia Johnston, JJ; Williamson, KA; Chou, CM et al. J. Med. Genet., DOI://10.1136/jmedgenet-2018-105836 (2019)
- Immunoelectron Microscopy of Viral Antigens Gulati, NM; Torian, U; Gallagher, JR; Harris, AK; Curr Protoc Microbiol, DOI://10.1002/cpmc.86 (2019)
- The nucleoporin ELYS regulates nuclear size by controlling NPC number and nuclear import capacity Jevtić, P; Schibler, AC; Wesley, CC; Pegoraro, G; Misteli, T; Levy, DL; , EMBO Rep., DOI://10.15252/embr.201847283 (2019)
- Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma Gryder, BE; Pomella, S; Sayers, C et al. Nat. Genet., DOI://10.1038/s41588-019-0534-4 (2019)
- Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma Yeung, C; Gibson, AE; Issaq, SH et al. Cancer Res., DOI://10.1158/0008-5472.CAN-19-0217 (2019)
- Intra-Vκ Cluster Recombination Shapes the Ig Kappa Locus Repertoire Shinoda, K; Maman, Y; Canela, A; Schatz, DG; Livak, F; Nussenzweig, A; , Cell Rep, DOI://10.1016/j.celrep.2019.11.088 (2019)
- Targeting the Chromosomal Passenger Complex Subunit INCENP Induces Polyploidization, Apoptosis, and Senescence in Neuroblastoma Sun, M; Veschi, V; Bagchi, S et al. Cancer Res., DOI://10.1158/0008-5472.CAN-19-0695 (2019)
- Meta-analysis of Chromatin Programming by Steroid Receptors Paakinaho, V; Swinstead, EE; Presman, DM; Grøntved, L; Hager, GL; , Cell Rep, DOI://10.1016/j.celrep.2019.08.039 (2019)
- Sympathetic activity contributes to the fMRI signal Özbay, PS; Chang, C; Picchioni, D et al. Commun Biol, DOI://10.1038/s42003-019-0659-0 (2019)
- Evidence for a Causal Role of the SH2B3-β 2 M Axis in Blood Pressure Regulation Keefe, JA; Hwang, SJ; Huan, T et al. Hypertension, DOI://10.1161/HYPERTENSIONAHA.118.12094 (2019)
- Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus Mistry, P; Nakabo, S; O'Neil, L et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1908576116 (2019)
- The Bone Marrow Protects and Optimizes Immunological Memory during Dietary Restriction Collins, N; Han, SJ; Enamorado, M et al. Cell, DOI://10.1016/j.cell.2019.07.049 (2019)
- Relationship between human leukocyte antigen alleles and risk of Kaposi's sarcoma in Cameroon Cornejo Castro, EM; Morrison, BJ; Marshall, VA et al. Genes Immun., DOI://10.1038/s41435-019-0077-9 (2019)
- Integration of TGF-β-induced Smad signaling in the insulin-induced transcriptional response in endothelial cells Budi, EH; Hoffman, S; Gao, S; Zhang, YE; Derynck, R; , Sci Rep, DOI://10.1038/s41598-019-53490-x (2019)
- Development of R7BP inhibitors through cross-linking coupled mass spectrometry and integrated modeling Adikaram, PR; Zhang, JH; Kittock, CM et al. Commun Biol, DOI://10.1038/s42003-019-0585-1 (2019)
- Differential expression and subcellular localization of Copines in mouse retina Goel, M; Li, T; Badea, TC; J. Comp. Neurol., DOI://10.1002/cne.24684 (2019)
- Identification of Novel Pathways Associated with Patterned Cerebellar Purkinje Neuron Degeneration in Niemann-Pick Disease, Type C1 Martin, KB; Williams, IM; Cluzeau, CV et al. Int J Mol Sci, DOI://10.3390/ijms21010292 (2019)
- A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers El Khattabi, L; Zhao, H; Kalchschmidt, J et al. Cell, DOI://10.1016/j.cell.2019.07.011 (2019)
- Temperature-dependent regulation of upstream open reading frame translation in S. cerevisiae Kulkarni, SD; Zhou, F; Sen, ND; Zhang, H; Hinnebusch, AG; Lorsch, JR; BMC Biol., DOI://10.1186/s12915-019-0718-5 (2019)
- A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity Bradfield, JP; Vogelezang, S; Felix, JF et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddz161 (2019)
- Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice Wang, Z; Xu, X; Li, JL; Palmer, C; Maric, D; Dean, J; Nat Commun, DOI://10.1038/s41467-019-13193-3 (2019)
- A Peripheral Blood DNA Methylation Signature of Hepatic Fat Reveals a Potential Causal Pathway for Nonalcoholic Fatty Liver Disease Ma, J; Nano, J; Ding, J et al. Diabetes, DOI://10.2337/DB18-1193 (2019)
- Liver- and Microbiome-derived Bile Acids Accumulate in Human Breast Tumors and Inhibit Growth and Improve Patient Survival Tang, W; Putluri, V; Ambati, CR; Dorsey, TH; Putluri, N; Ambs, S; , Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-19-0094 (2019)
- ARSA variants in α-synucleinopathies Makarious, MB; Diez-Fairen, M; Krohn, L et al. Brain, DOI://10.1093/brain/awz340 (2019)
- A New Lineage of Cryptococcus gattii (VGV) Discovered in the Central Zambezian Miombo Woodlands Farrer, RA; Chang, M; Davis, MJ et al. mBio, DOI://10.1128/mBio.02306-19 (2019)
- Contribution of SLC22A12 on hypouricemia and its clinical significance for screening purposes Cha, DH; Gee, HY; Cachau, R et al. Sci Rep, DOI://10.1038/s41598-019-50798-6 (2019)
- Dose coefficients of mesh-type ICRP reference computational phantoms for external exposures of neutrons, protons, and helium ions Yeom YS, Choi C, et al. Nuc. Engg. Tech., doi://10.1016/j.net.2019.12.020 (2019)
- White Blood Cell Count and Risk of Incident Lung Cancer in the UK Biobank Wong JYY, Bassig BA et al. JNCI Cancer Spectrum, doi://10.1093/jncics/pkz102 (2019)
- Cryo-EM structure of substrate-free E. coli Lon protease provides insights into the dynamics of Lon machinery Botos I, Lountos GT et al. Cur. Res. Struct. Biol. , doi://0.1016/j.crstbi.2019.10.001 (2019)
- Dosimetric impact of voxel resolutions of computational human phantoms for external photon exposure Choonsik Lee, Andreu Badal, Yeon Soo Yeom, Keith T Griffin and Dayton McMillan Biomed. Phys. Engg. Exp. , doi://10.1088/2057-1976/ab2850 (2019)
- Joint modelling of competing risks and current status data: an application to a spontaneous labour study Youjin Lee Mei; Cheng Wang; Katherine L. Grantz; Rajeshwari Sundaram Royal Statistical Society, doi://10.1111/rssc.12351 (2019)
- Keratinocyte-intrinsic MHCII expression controls microbiota-induced Th1 cell responses Tamoutounour, S; Han, SJ; Deckers, J et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1912432116 (2019)
- Mammographic breast density and its association with urinary estrogens and the fecal microbiota in postmenopausal women Jones, GS; Spencer Feigelson, H; Falk, RT et al. PLoS ONE, DOI://10.1371/journal.pone.0216114 (2019)
- NMR Analysis of Apo Glutamine-Binding Protein Exposes Challenges in the Study of Interdomain Dynamics Kooshapur, H; Ma, J; Tjandra, N; Bermejo, GA; Angew. Chem. Int. Ed. Engl., DOI://10.1002/anie.201911015 (2019)
- Proteomics Pipeline for Identifying Variant Proteins in Plasmodium falciparum Parasites Isolated from Children Presenting with Malaria Gonzales Hurtado, PA; Morrison, R; Ribeiro, JMC et al. J. Proteome Res., DOI://10.1021/acs.jproteome.9b00169 (2019)
- Oncoviruses Can Drive Cancer by Rewiring Signaling Pathways Through Interface Mimicry Guven-Maiorov, E; Tsai, CJ; Nussinov, R; , Front Oncol, DOI://10.3389/fonc.2019.01236 (2019)
- Rat Orbitofrontal Ensemble Activity Contains Multiplexed but Dissociable Representations of Value and Task Structure in an Odor Sequence Task Zhou, J; Gardner, MPH; Stalnaker, TA et al. Curr. Biol., DOI://10.1016/j.cub.2019.01.048 (2019)
- Non-Leishmania Parasite in Fatal Visceral Leishmaniasis-Like Disease, Brazil Maruyama, SR; de Santana, AKM; Takamiya, NT et al. Emerging Infect. Dis., DOI://10.3201/eid2511.181548 (2019)
- A Phase II Study of Tumor-infiltrating Lymphocyte Therapy for Human Papillomavirus-associated Epithelial Cancers Stevanovic, S; Helman, SR; Wunderlich, JR et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-2722 (2019)
- Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans Mitchell, KA; Nichols, N; Tang, W et al. Nat Commun, DOI://10.1038/s41467-019-13732-y (2019)
- The endocytic membrane trafficking pathway plays a major role in the risk of Parkinson's disease Bandres-Ciga, S; Saez-Atienzar, S; Bonet-Ponce, L et al. Mov. Disord., DOI://10.1002/mds.27614 (2019)
- The GATOR complex regulates an essential response to meiotic double-stranded breaks in Drosophila Wei, Y; Bettedi, L; Ting, CY et al. Elife, DOI://10.7554/eLife.42149 (2019)
- Next generation sequencing and the classical HLA loci in full heritage Pima Indians of Arizona: Defining the core HLA variation for North American Paleo-Indians Williams, RC; Knowler, WC; Shuldiner, AR et al. Hum Immunol, DOI://10.1016/j.humimm.2019.10.002 (2019)
- Autosomal recessive congenital cataracts linked to HSF4 in a consanguineous Pakistani family Jiao, X; Khan, SY; Kaul, H et al. PLoS ONE, DOI://10.1371/journal.pone.0225010 (2019)
- White Matter Microstructure in Pediatric Bipolar Disorder and Disruptive Mood Dysregulation Disorder Linke, JO; Adleman, NE; Sarlls, J et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2019.05.035 (2019)
- DENND5B Regulates Intestinal Triglyceride Absorption and Body Mass Gordon, SM; Neufeld, EB; Yang, Z et al. Sci Rep, DOI://10.1038/s41598-019-40296-0 (2019)
- Reply to Spreng et al.: Multiecho fMRI denoising does not remove global motion-associated respiratory signals Power, JD; Lynch, CJ; Gilmore, AW; Gotts, SJ; Martin, A; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1909852116 (2019)
- HiPLA: High-throughput imaging proximity ligation assay Serebryannyy, LA; Misteli, T; , Methods, DOI://10.1016/j.ymeth.2018.11.004 (2019)
- Single molecule analysis of lamin dynamics Serebryannyy, LA; Ball, DA; Karpova, TS; Misteli, T; , Methods, DOI://10.1016/j.ymeth.2018.08.009 (2019)
- HNRNPH1-dependent splicing of a fusion oncogene reveals a targetable RNA G-quadruplex interaction Neckles, C; Boer, RE; Aboreden, N et al. RNA, DOI://10.1261/rna.072454.119 (2019)
- Correction to: ATAC2GRN: optimized ATAC-seq and DNase1-seq pipelines for rapid and accurate genome regulatory network inference Pranzatelli, TJF; Michae, DG; Chiorini, JA; , BMC Genomics, DOI://10.1186/s12864-019-5441-7 (2019)
- Head and Neck Cancers Promote an Inflammatory Transcriptome Through Coactivation of Classic and Alternative NF-κB Pathways Yang, X; Cheng, H; Chen, J et al. Cancer Immunol Res, DOI://10.1158/2326-6066.CIR-18-0832 (2019)
- Enhancement of LIN28B-induced hematopoietic reprogramming by IGF2BP3 Wang, S; Chim, B; Su, Y et al. Genes Dev., DOI://10.1101/gad.325100.119 (2019)
- Genome-Wide Profiling of Cervical RNA-Binding Proteins Identifies Human Papillomavirus Regulation of RNASEH2A Expression by Viral E7 and E2F1 Xu, J; Liu, H; Yang, Y et al. mBio, DOI://10.1128/mBio.02687-18 (2019)
- Classification of GBA Variants and Their Effects in Synucleinopathies Gan-Or, Z; Alcalay, RN; Makarious, MB; Scholz, SW; Blauwendraat, C; , ; Mov. Disord., DOI://10.1002/mds.27803 (2019)
- H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development Jang, Y; Broun, A; Wang, C et al. Nucleic Acids Res., DOI://10.1093/nar/gky982 (2019)
- MicroRNA-mediated control of developmental lymphangiogenesis Jung, HM; Hu, CT; Fister, AM et al. Elife, DOI://10.7554/eLife.46007 (2019)
- Immunoprecipitation and Sequencing of Acetylated RNA Arango, D; Sturgill, D; Oberdoerffer, S; , Bio Protoc, DOI://10.21769/BioProtoc.3278 (2019)
- Correction: Conserved mRNA-granule component Scd6 targets Dhh1 to repress translation initiation and activates Dcp2-mediated mRNA decay in vivo Zeidan, Q; He, F; Zhang, F; Zhang, H; Jacobson, A; Hinnebusch, AG; PLoS Genet., DOI://10.1371/journal.pgen.1008299 (2019)
- Understanding Cancer Through the Lens of Epigenetic Inheritance, Allele-Specific Gene Expression, and High-Throughput Technology Lee, MP Front Oncol, DOI://10.3389/fonc.2019.00794 (2019)
- A deconvolution algorithm for multi-echo functional MRI: Multi-echo Sparse Paradigm Free Mapping Caballero-Gaudes, C; Moia, S; Panwar, P; Bandettini, PA; Gonzalez-Castillo, J; Neuroimage, DOI://10.1016/j.neuroimage.2019.116081 (2019)
- A tail of two sides: Artificially doubled false positive rates in neuroimaging due to the sidedness choice with t-tests Chen, G; Cox, RW; Glen, DR; Rajendra, JK; Reynolds, RC; Taylor, PA; Hum Brain Mapp, DOI://10.1002/hbm.24399 (2019)
- Association of Maternal Exposure to Persistent Organic Pollutants in Early Pregnancy With Fetal Growth Ouidir, M; Buck Louis, GM; Kanner, J et al. JAMA Pediatr, DOI://10.1001/jamapediatrics.2019.5104 (2019)
- Modeling ligand docking to RNA in the design of RNA-based nanostructures Kasprzak, WK; Ahmed, NA; Shapiro, BA; Curr. Opin. Biotechnol., DOI://10.1016/j.copbio.2019.10.010 (2019)
- Integrating Hi-C links with assembly graphs for chromosome-scale assembly Ghurye, J; Rhie, A; Walenz, BP et al. PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1007273 (2019)
- Magnetoencephalographic Correlates of Suicidal Ideation in Major Depression Gilbert, JR; Ballard, ED; Galiano, CS; Nugent, AC; Zarate, CA; Biol Psychiatry Cogn Neurosci Neuroimaging, DOI://10.1016/j.bpsc.2019.11.011 (2019)
- Single Cell and Single Nucleus RNA-Seq Reveal Cellular Heterogeneity and Homeostatic Regulatory Networks in Adult Mouse Stria Vascularis Korrapati, S; Taukulis, I; Olszewski, R et al. Front Mol Neurosci, DOI://10.3389/fnmol.2019.00316 (2019)
- Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods Hu, X; Compton, JR; Legler, PM; J Vis Exp, DOI://10.3791/60421 (2019)
- Single-Cell Profiling Defines Transcriptomic Signatures Specific to Tumor-Reactive versus Virus-Responsive CD4+ T Cells Magen, A; Nie, J; Ciucci, T et al. Cell Rep, DOI://10.1016/j.celrep.2019.10.131 (2019)
- Transcriptome-based molecular staging of human stem cell-derived retinal organoids uncovers accelerated photoreceptor differentiation by 9-cis retinal Kaya KD, Chen HY, Brooks MJ et al Mol Vis (2019)
- Novel Protease Inhibitors Containing C-5-Modified bis-Tetrahydrofuranylurethane and Aminobenzothiazole as P2 and P2' Ligands That Exert Potent Antiviral Activity against Highly Multidrug-Resistant HIV-1 with a High Genetic Barrier against the Emergence of Drug Resistance Takamatsu, Y; Aoki, M; Bulut, H et al. Antimicrob. Agents Chemother., DOI://10.1128/AAC.00372-19 (2019)
- Benchmarking the Performance of Time-Dependent Density Functional Theory Methods on Biochromophores Shao, Y; Mei, Y; Sundholm, D; Kaila, VRI; J Chem Theory Comput, DOI://10.1021/acs.jctc.9b00823 (2019)
- Novel Central Nervous System (CNS)-Targeting Protease Inhibitors for Drug-Resistant HIV Infection and HIV-Associated CNS Complications Amano, M; Salcedo-Gómez, PM; Yedidi, RS et al. Antimicrob. Agents Chemother., DOI://10.1128/AAC.00466-19 (2019)
- HLA and autoantibodies define scleroderma subtypes and risk in African and European Americans and suggest a role for molecular mimicry Gourh, P; Safran, SA; Alexander, T et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1906593116 (2019)
- Maternal fatty acid concentrations and newborn DNA methylation Robinson, SL; Mumford, SL; Guan, W et al. Am. J. Clin. Nutr., DOI://10.1093/ajcn/nqz311 (2019)
- DHHC20 Palmitoyl-Transferase Reshapes the Membrane to Foster Catalysis Stix, R; Song, J; Banerjee, A; Faraldo-Gómez, JD; Biophys. J., DOI://10.1016/j.bpj.2019.11.003 (2019)
- Analysis of ordered composite endpoints Follmann, D; Fay, MP; Hamasaki, T; Evans, S; Stat Med, DOI://10.1002/sim.8431 (2019)
- Large-scale state-dependent membrane remodeling by a transporter protein Zhou, W; Fiorin, G; Anselmi, C et al. Elife, DOI://10.7554/eLife.50576 (2019)
- CNVScope: Visually Exploring Copy Number Aberrations in Cancer Genomes Dalgleish, JL; Wang, Y; Zhu, J; Meltzer, PS; Cancer Inform, DOI://10.1177/1176935119890290 (2019)
- Identification of 102 Correlations between Serum Metabolites and Habitual Diet in a Metabolomics Study of the Prostate, Lung, Colorectal, and Ovarian Cancer Trial Mazzilli, KM; McClain, KM; Lipworth, L et al. J. Nutr., DOI://10.1093/jn/nxz300 (2019)
- Permeability of membranes in the liquid ordered and liquid disordered phases Ghysels, A; Krämer, A; Venable, RM et al. Nat Commun, DOI://10.1038/s41467-019-13432-7 (2019)
- A Thpok-Directed Transcriptional Circuitry Promotes Bcl6 and Maf Expression to Orchestrate T Follicular Helper Differentiation Vacchio, MS; Ciucci, T; Gao, Y et al. Immunity, DOI://10.1016/j.immuni.2019.06.023 (2019)
- SummaryAUC: a tool for evaluating the performance of polygenic risk prediction models in validation datasets with only summary level statistics Song, L; Liu, A; Shi, J; , ; Bioinformatics, DOI://10.1093/bioinformatics/btz176 (2019)
- Accurate Prediction for Antibody Resistance of Clinical HIV-1 Isolates Rawi, R; Mall, R; Shen, CH et al. Sci Rep, DOI://10.1038/s41598-019-50635-w (2019)
- Gene gain and loss push prokaryotes beyond the homologous recombination barrier and accelerate genome sequence divergence Iranzo, J; Wolf, YI; Koonin, EV; Sela, I; Nat Commun, DOI://10.1038/s41467-019-13429-2 (2019)
- Mash Screen: high-throughput sequence containment estimation for genome discovery Ondov, BD; Starrett, GJ; Sappington, A et al. Genome Biol., DOI://10.1186/s13059-019-1841-x (2019)
- The scale-invariant, temporal profile of neuronal avalanches in relation to cortical γ-oscillations Miller, SR; Yu, S; Plenz, D; Sci Rep, DOI://10.1038/s41598-019-52326-y (2019)
- Myc controls a distinct transcriptional program in fetal thymic epithelial cells that determines thymus growth Cowan, JE; Malin, J; Zhao, Y et al. Nat Commun, DOI://10.1038/s41467-019-13465-y (2019)
- Ca2+-Dependent Switch of Calmodulin Interaction Mode with Tandem IQ Motifs in the Scaffolding Protein IQGAP1 Zhang, M; Li, Z; Jang, H; Hedman, AC; Sacks, DB; Nussinov, R; Biochemistry, DOI://10.1021/acs.biochem.9b00854 (2019)
- Contribution of Common Genetic Variants to Familial Aggregation of Disease and Implications for Sequencing Studies Schlafly, A; Pfeiffer, RM; Nagore, E et al. PLoS Genet., DOI://10.1371/journal.pgen.1008490 (2019)
- Mechanistic link between right prefrontal cortical activity and anxious arousal revealed using transcranial magnetic stimulation in healthy subjects Balderston, NL; Beydler, EM; Roberts, C et al. Neuropsychopharmacology, DOI://10.1038/s41386-019-0583-5 (2019)
- Race-specific alterations in DNA methylation among middle-aged African Americans and Whites with metabolic syndrome Chitrala, KN; Hernandez, DG; Nalls, MA et al. Epigenetics, DOI://10.1080/15592294.2019.1695340 (2019)
- A3 adenosine receptor activation mechanisms: molecular dynamics analysis of inactive, active, and fully active states Ciancetta, A; Rubio, P; Lieberman, DI; Jacobson, KA; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-019-00246-4 (2019)
- Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls Flannick, J; Mercader, JM; Fuchsberger, C et al. Nature, DOI://10.1038/s41586-019-1231-2 (2019)
- Knowing What You Know in Brain Segmentation Using Bayesian Deep Neural Networks McClure, P; Rho, N; Lee, JA et al. Front Neuroinform, DOI://10.3389/fninf.2019.00067 (2019)
- Commensal microbiota drive the functional diversification of colon macrophages Kang, B; Alvarado, LJ; Kim, T et al. Mucosal Immunol, DOI://10.1038/s41385-019-0228-3 (2019)
- Single cell analysis of adult mouse skeletal muscle stem cells in homeostatic and regenerative conditions Dell'Orso, S; Juan, AH; Ko, KD et al. Development, DOI://10.1242/dev.174177 (2019)
- Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle Taylor, DL; Jackson, AU; Narisu, N et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1814263116 (2019)
- Author Correction: Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses Kanekiyo, M; Joyce, MG; Gillespie, RA et al. Nat. Immunol., DOI://10.1038/s41590-019-0395-0 (2019)
- Correction: CAPN1 is a novel binding partner and regulator of the tumor suppressor NF1 in melanoma Alon, M; Arafeh, R; Lee, JS et al. Oncotarget, DOI://10.18632/oncotarget.26685 (2019)
- Correction: The zinc-finger protein CLAMP promotes gypsy chromatin insulator function in Drosophila (doi:10.1242/jcs.226092) Bag, I; Dale, RK; Palmer, C; Lei, EP; J. Cell. Sci., DOI://10.1242/jcs.231977 (2019)
- Multiomic Profiling Identifies cis-Regulatory Networks Underlying Human Pancreatic β Cell Identity and Function Lawlor, N; Márquez, EJ; Orchard, P et al. Cell Rep, DOI://10.1016/j.celrep.2018.12.083 (2019)
- Second Case of HOIP Deficiency Expands Clinical Features and Defines Inflammatory Transcriptome Regulated by LUBAC Oda, H; Beck, DB; Kuehn, HS et al. Front Immunol, DOI://10.3389/fimmu.2019.00479 (2019)
- Katanin Grips the β-Tubulin Tail through an Electropositive Double Spiral to Sever Microtubules Zehr, EA; Szyk, A; Szczesna, E; Roll-Mecak, A; Dev. Cell, DOI://10.1016/j.devcel.2019.10.010 (2019)
- Data augmentation using generative adversarial networks (CycleGAN) to improve generalizability in CT segmentation tasks Sandfort, V; Yan, K; Pickhardt, PJ; Summers, RM; Sci Rep, DOI://10.1038/s41598-019-52737-x (2019)
- Author Correction: In vivo tropism of Salmonella Typhi toxin to cells expressing a multiantennal glycan receptor Yang, YA; Lee, S; Zhao, J et al. Nat Microbiol, DOI://10.1038/s41564-019-0505-7 (2019)
- Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression Forstner, AJ; Awasthi, S; Wolf, C et al. Mol. Psychiatry, DOI://10.1038/s41380-019-0590-2 (2019)
- Preventing dysbiosis of the neonatal mouse intestinal microbiome protects against late-onset sepsis Singer, JR; Blosser, EG; Zindl, CL et al. Nat. Med., DOI://10.1038/s41591-019-0640-y (2019)
- Splicing factor DHX15 affects tp53 and mdm2 expression via alternate splicing and promoter usage McElderry, J; Carrington, B; Bishop, K et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddz261 (2019)
- Tango1 coordinates the formation of ER/Golgi docking sites to mediate secretory granule formation Reynolds, HM; Zhang, L; Tran, DT; Ten Hagen, KG; J. Biol. Chem., DOI://10.1074/jbc.RA119.011063 (2019)
- Williams syndrome hemideletion and LIMK1 variation both affect dorsal stream functional connectivity Gregory, MD; Mervis, CB; Elliott, ML et al. Brain, DOI://10.1093/brain/awz323 (2019)
- Reducing motion sensitivity in 3D high-resolution T2*-weighted MRI by navigator-based motion and nonlinear magnetic field correction Liu, J; van Gelderen, P; de Zwart, JA; Duyn, JH; Neuroimage, DOI://10.1016/j.neuroimage.2019.116332 (2019)
- Single-Cell Transcriptome Analysis Reveals Gene Signatures Associated with T-cell Persistence Following Adoptive Cell Therapy Lu, YC; Jia, L; Zheng, Z; Tran, E; Robbins, PF; Rosenberg, SA; Cancer Immunol Res, DOI://10.1158/2326-6066.CIR-19-0299 (2019)
- Dose coefficients of percentile-specific computational phantoms for photon external exposures Yeom, YS; Han, H; Choi, C; Shin, B; Kim, CH; Lee, C; Radiat Environ Biophys, DOI://10.1007/s00411-019-00818-w (2019)
- Characteristics of respiratory measures in young adults scanned at rest, including systematic changes and "missed" deep breaths Power, JD; Lynch, CJ; Dubin, MJ; Silver, BM; Martin, A; Jones, RM; Neuroimage, DOI://10.1016/j.neuroimage.2019.116234 (2019)
- Impact of CMV Infection on Natural Killer Cell Clonal Repertoire in CMV-Naïve Rhesus Macaques Truitt, LL; Yang, D; Espinoza, DA et al. Front Immunol, DOI://10.3389/fimmu.2019.02381 (2019)
- Prepontine non-giant neurons drive flexible escape behavior in zebrafish Marquart, GD; Tabor, KM; Bergeron, SA; Briggman, KL; Burgess, HA; PLoS Biol., DOI://10.1371/journal.pbio.3000480 (2019)
- Approximation of Bias and Mean Squared Error in Two-sample Mendelian Randomization Analyses Deng, L; Zhang, H; Song, L; Yu, K; Biometrics, DOI://10.1111/biom.13169 (2019)
- AI Meets Exascale Computing: Advancing Cancer Research With Large-Scale High Performance Computing Bhattacharya, T; Brettin, T; Doroshow, JH et al. Front Oncol, DOI://10.3389/fonc.2019.00984 (2019)
- Plasmid Dissemination and Selection of a Multidrug-Resistant Klebsiella pneumoniae Strain during Transplant-Associated Antibiotic Therapy Conlan, S; Lau, AF; Deming, C et al. MBio, DOI://10.1128/mBio.00652-19 (2019)
- Stereotyped transcriptomic transformation of somatosensory neurons in response to injury Nguyen, MQ; Le Pichon, CE; Ryba, N; Elife, DOI://10.7554/eLife.49679 (2019)
- Cryo-EM structure of the bacterial Ton motor subcomplex ExbB-ExbD provides information on structure and stoichiometry Celia, H; Botos, I; Ni, X et al. Commun Biol, DOI://10.1038/s42003-019-0604-2 (2019)
- Dog10K: an international sequencing effort to advance studies of canine domestication, phenotypes and health Ostrander, EA; Wang, GD; Larson, G et al. Natl Sci Rev, DOI://10.1093/nsr/nwz049 (2019)
- Single-Cell RNA-seq Identifies Cell Diversity in Embryonic Salivary Glands Sekiguchi, R; Martin, D; , ; Yamada, KM; J. Dent. Res., DOI://10.1177/0022034519883888 (2019)
- Embryo polarity in moth flies and mosquitoes relies on distinct old genes with localized transcript isoforms Yoon, Y; Klomp, J; Martin-Martin, I et al. Elife, DOI://10.7554/eLife.46711 (2019)
- Differential Nucleosome Spacing in Neurons and Glia Clark, SC; Chereji, RV; Lee, PR; Fields, RD; Clark, DJ; Neurosci. Lett., DOI://10.1016/j.neulet.2019.134559 (2019)
- Improved Retinal Organoid Differentiation by Modulating Signaling Pathways Revealed by Comparative Transcriptome Analyses with Development In Vivo Brooks, MJ; Chen, HY; Kelley, RA et al. Stem Cell Reports, DOI://10.1016/j.stemcr.2019.09.009 (2019)
- Gata2 deficiency delays leukemogenesis while contributing to aggressive leukemia phenotype in Cbfb-MYH11 knockin mice Saida, S; Zhen, T; Kim, E et al. Leukemia, DOI://10.1038/s41375-019-0605-7 (2019)
- Cell Type- and Sex-Dependent Transcriptome Profiles of Rat Anterior Pituitary Cells Fletcher, PA; Smiljanic, K; Maso Prévide, R et al. Front Endocrinol (Lausanne), DOI://10.3389/fendo.2019.00623 (2019)
- Differences in Genome-wide DNA Methylation Profiles in Breast Milk by Race and Lactation Duration Davis Lynn, BC; Bodelon, C; Pfeiffer, RM et al. Cancer Prev Res (Phila), DOI://10.1158/1940-6207.CAPR-19-0169 (2019)
- Strong dependence of the nano-bio interactions on core morphology and layer composition of ultrasmall nanostructures Hassan, SA J Chem Phys, DOI://10.1063/1.5115192 (2019)
- Discovery and Development of Anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication Maeda, K; Das, D; Kobayakawa, T; Tamamura, H; Takeuchi, H; Curr Top Med Chem, DOI://10.2174/1568026619666190712204603 (2019)
- Direct Derivation of Free Energies of Membrane Deformation and Other Solvent Density Variations From Enhanced Sampling Molecular Dynamics Fiorin, G; Marinelli, F; Faraldo-Gómez, JD; J Comput Chem, DOI://10.1002/jcc.26075 (2019)
- Clonal tracking of erythropoiesis in rhesus macaques Fan, X; Wu, C; Truitt, LL et al. Haematologica, DOI://10.3324/haematol.2019.231811 (2019)
- Molecular Classification of Epithelial Ovarian Cancer Based on Methylation Profiling: Evidence for Survival Heterogeneity Bodelon, C; Killian, JK; Sampson, JN et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-3720 (2019)
- Layer-dependent activity in human prefrontal cortex during working memory Finn, ES; Huber, L; Jangraw, DC; Molfese, PJ; Bandettini, PA; Nat. Neurosci., DOI://10.1038/s41593-019-0487-z (2019)
- Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution Justice, AE; Karaderi, T; Highland, HM et al. Nat. Genet., DOI://10.1038/s41588-018-0334-2 (2019)
- Dynamic Emergence of Mismatch Repair Deficiency Facilitates Rapid Evolution of Ceftazidime-Avibactam Resistance in Pseudomonas aeruginosa Acute Infection Khil, PP; Dulanto Chiang, A; Ho, J et al. MBio, DOI://10.1128/mBio.01822-19 (2019)
- Drosophila Heterochromatin Stabilization Requires the Zinc-Finger Protein Small Ovary Benner, L; Castro, EA; Whitworth, C et al. Genetics, DOI://10.1534/genetics.119.302590 (2019)
- Dual antagonist of cIAP/XIAP ASTX660 sensitizes HPV-and HPV+ head and neck cancers to TNFα, TRAIL, and radiation Therapy Xiao, R; An, Y; Ye, W et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-3802 (2019)
- Gene-based association analysis of survival traits via functional regression-based mixed effect cox models for related samples Chiu, CY; Zhang, B; Wang, S et al. Genet. Epidemiol., DOI://10.1002/gepi.22254 (2019)
- Molecular characterization of respiratory syncytial viruses circulating in a paediatric cohort in Amman, Jordan Trovão, NS; Khuri-Bulos, N; Tan, Y et al. Microb Genom, DOI://10.1099/mgen.0.000292 (2019)
- A Novel Bromine-Containing Paroxetine Analogue Provides Mechanistic Clues for Binding Ambiguity at the Central Primary Binding Site of the Serotonin Transporter Slack, RD; Abramyan, AM; Tang, H et al. ACS Chem Neurosci, DOI://10.1021/acschemneuro.9b00375 (2019)
- Low Abundance of Circulating Tumor DNA in Localized Prostate Cancer Hennigan, ST; Trostel, SY; Terrigino, NT et al. JCO Precis Oncol, DOI://10.1200/PO.19.00176 (2019)
- Automated Liver Fat Quantification at Nonenhanced Abdominal CT for Population-based Steatosis Assessment Graffy, PM; Sandfort, V; Summers, RM; Pickhardt, PJ; Radiology, DOI://10.1148/radiol.2019190512 (2019)
- lncRNA expression predicts mRNA abundance Pacholewska, A; Sung, MH; Epigenomics, DOI://10.2217/epi-2019-0003 (2019)
- Quantitative MNase-seq accurately maps nucleosome occupancy levels Chereji, RV; Bryson, TD; Henikoff, S; Genome Biol., DOI://10.1186/s13059-019-1815-z (2019)
- Synthesis and Characterization of Bodipy-FL-Cyclosporine A as a Substrate for Multidrug Resistance-Linked P-Glycoprotein (ABCB1) Sajid, A; Raju, N; Lusvarghi, S; Vahedi, S; Swenson, RE; Ambudkar, SV; Drug Metab. Dispos., DOI://10.1124/dmd.119.087734 (2019)
- Accessibility of promoter DNA is not the primary determinant of chromatin-mediated gene regulation Chereji, RV; Eriksson, PR; Ocampo, J; Prajapati, HK; Clark, DJ; Genome Res., DOI://10.1101/gr.249326.119 (2019)
- Structure of the primed state of the ATPase domain of chromatin remodeling factor ISWI bound to the nucleosome Chittori, S; Hong, J; Bai, Y; Subramaniam, S; Nucleic Acids Res., DOI://10.1093/nar/gkz670 (2019)
- De Novo Variants in WDR37 Are Associated with Epilepsy, Colobomas, Dysmorphism, Developmental Delay, Intellectual Disability, and Cerebellar Hypoplasia Kanca, O; Andrews, JC; Lee, PT et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2019.06.014 (2019)
- A Monte Carlo model for organ dose reconstruction of patients in Pencil Beam Scanning (PBS) proton therapy for epidemiologic studies of late effects Yeom, YS; Kuzmin, G; Griffin, KT et al. J Radiol Prot, DOI://10.1088/1361-6498/ab437d (2019)
- NMR characterization of rearranged staurosporine aglycone analogues from the marine sponge Damiria sp Tran, TD; Cartner, LK; Bokesch, HR et al. Magn Reson Chem, DOI://10.1002/mrc.4932 (2019)
- The Spodoptera frugiperda Sf9 cell line is a heterogeneous population of rhabdovirus-infected and virus-negative cells: Isolation and characterization of cell clones containing rhabdovirus X-gene variants and virus-negative cell clones Ma, H; Nandakumar, S; Bae, EH; Chin, PJ; Khan, AS; Virology, DOI://10.1016/j.virol.2019.08.001 (2019)
- Genome-wide DNA methylation analysis of colorectal adenomas with and without recurrence reveals an association between cytosine-phosphate-guanine methylation and histological subtypes Fiedler, D; Hirsch, D; El Hajj, N et al. Genes Chromosomes Cancer, DOI://10.1002/gcc.22787 (2019)
- The Structural Basis of the Farnesylated and Methylated KRas4B Interaction with Calmodulin Jang, H; Banerjee, A; Marcus, K et al. Structure, DOI://10.1016/j.str.2019.08.009 (2019)
- Imaging the spontaneous flow of thought: Distinct periods of cognition contribute to dynamic functional connectivity during rest Gonzalez-Castillo, J; Caballero-Gaudes, C; Topolski, N; Handwerker, DA; Pereira, F; Bandettini, PA; Neuroimage, DOI://10.1016/j.neuroimage.2019.116129 (2019)
- Papillomavirus can be transmitted through the blood and produce infections in blood recipients: Evidence from two animal models Cladel, NM; Jiang, P; Li, JJ et al. Emerg Microbes Infect, DOI://10.1080/22221751.2019.1637072 (2019)
- Cysteinyl-tRNA Synthetase Mutations Cause a Multi-System, Recessive Disease That Includes Microcephaly, Developmental Delay, and Brittle Hair and Nails Kuo, ME; Theil, AF; Kievit, A et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2019.01.006 (2019)
- Sex differences in the associations of placental epigenetic aging with fetal growth Tekola-Ayele, F; Workalemahu, T; Gorfu, G et al. Aging (Albany NY), DOI://10.18632/aging.102124 (2019)
- Genome-wide association study for proliferative diabetic retinopathy in Africans Liu, C; Chen, G; Bentley, AR et al. NPJ Genom Med, DOI://10.1038/s41525-019-0094-7 (2019)
- Cohesin Impedes Heterochromatin Assembly in Fission Yeast Cells Lacking Pds5 Folco, HD; McCue, A; Balachandran, V; Grewal, SIS; Genetics, DOI://10.1534/genetics.119.302256 (2019)
- T-Cell Deletion of MyD88 Connects IL17 and IκBζ to RAS Oncogenesis Cataisson, C; Salcedo, R; Michalowski, AM et al. Mol. Cancer Res., DOI://10.1158/1541-7786.MCR-19-0227 (2019)
- Novel pathogenic COX20 variants causing dysarthria, ataxia, and sensory neuropathy Otero, MG; Tiongson, E; Diaz, F et al. Ann Clin Transl Neurol, DOI://10.1002/acn3.661 (2019)
- Glucocorticoid receptor quaternary structure drives chromatin occupancy and transcriptional outcome Paakinaho, V; Johnson, TA; Presman, DM; Hager, GL; Genome Res., DOI://10.1101/gr.244814.118 (2019)
- Modulation of Target Antigen Density Improves CAR T-cell Functionality and Persistence Ramakrishna, S; Highfill, SL; Walsh, Z et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-3784 (2019)
- Pathogenic TERT promoter variants in telomere diseases Gutierrez-Rodrigues, F; Donaires, FS; Pinto, A et al. Genet. Med., DOI://10.1038/s41436-018-0385-x (2019)
- Epigenetic aging is accelerated in alcohol use disorder and regulated by genetic variation in APOL2 Luo, A; Jung, J; Longley, M et al. Neuropsychopharmacology, DOI://10.1038/s41386-019-0500-y (2019)
- Relationship of DNA methylation to mutational changes and transcriptional organization in fusion-positive and fusion-negative rhabdomyosarcoma Sun, W; Chatterjee, B; Shern, JF et al. Int. J. Cancer, DOI://10.1002/ijc.32006 (2019)
- Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel Yin, Y; Le, SC; Hsu, AL; Borgnia, MJ; Yang, H; Lee, SY; Science, DOI://10.1126/science.aav9334 (2019)
- Genomic analyses in African populations identify novel risk loci for cleft palate Butali, A; Mossey, PA; Adeyemo, WL et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddy402 (2019)
- Laboratory mice born to wild mice have natural microbiota and model human immune responses Rosshart, SP; Herz, J; Vassallo, BG et al. Science, DOI://10.1126/science.aaw4361 (2019)
- T cell stemness and dysfunction in tumors are triggered by a common mechanism Vodnala, SK; Eil, R; Kishton, RJ et al. Science, DOI://10.1126/science.aau0135 (2019)
- Dynamical modeling of multi-scale variability in neuronal competition Cohen, BP; Chow, CC; Vattikuti, S; Commun Biol, DOI://10.1038/s42003-019-0555-7 (2019)
- Organ-specific dose coefficients derived from Monte Carlo simulations for historical (1930s to 1960s) fluoroscopic and radiographic examinations of tuberculosis patients Borrego, D; Apostoaei, AI; Thomas, BA et al. J Radiol Prot, DOI://10.1088/1361-6498/ab2f10 (2019)
- Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis Lam, KG; Brick, K; Cheng, G; Pratto, F; Camerini-Otero, RD; Nat Commun, DOI://10.1038/s41467-019-11820-7 (2019)
- The bZIP mutant CEBPB (V285A) has sequence specific DNA binding propensities similar to CREB1 Ray, S; Ufot, A; Assad, N et al. Biochim Biophys Acta Gene Regul Mech, DOI://10.1016/j.bbagrm.2019.02.002 (2019)
- Novel age-associated DNA methylation changes and epigenetic age acceleration in middle-aged African Americans and whites Tajuddin, SM; Hernandez, DG; Chen, BH et al. Clin Epigenetics, DOI://10.1186/s13148-019-0722-1 (2019)
- Resting-state connectivity of the bed nucleus of the stria terminalis and the central nucleus of the amygdala in clinical anxiet Torrisi, S; Alvarez, GM; Gorka, AX et al. J Psychiatry Neurosci, DOI://10.1503/jpn.180150 (2019)
- Insights into pediatric rhabdomyosarcoma research: Challenges and goals Yohe, ME; Heske, CM; Stewart, E et al. Pediatr Blood Cancer, DOI://10.1002/pbc.27869 (2019)
- Longitudinal Development of Social-Cognition Regions Covaries With Amygdala Volume in Children With Williams Syndrome Kuhney F, Kippenhan S et al Biol. Psych., doi:///10.1016/j.biopsych.2019.03.584 (2019)
- Mannobiose-Grafting Shifts PEI Charge and Biphasic Dependence on pH S Basu, R Venable et al Macro. Mat. Engg., doi://10.1002/macp.201800423 (2019)
- Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel Yin, Y; Wu, M; Hsu, AL et al. Nat Commun, DOI://10.1038/s41467-019-11733-5 (2019)
- TET-Catalyzed 5-Carboxylcytosine Promotes CTCF Binding to Suboptimal Sequences Genome-wide Nanan, KK; Sturgill, DM; Prigge, MF et al. iScience, DOI://10.1016/j.isci.2019.07.041 (2019)
- Transcriptome signature of cellular senescence Casella, G; Munk, R; Kim, KM et al. Nucleic Acids Res., DOI://10.1093/nar/gkz555 (2019)
- Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual Krebs, SJ; Kwon, YD; Schramm, CA et al. Immunity, DOI://10.1016/j.immuni.2019.02.008 (2019)
- Large-Scale Communication in the Human Brain Is Rhythmically Modulated through Alpha Coherence Chapeton, JI; Haque, R; Wittig, JH; Inati, SK; Zaghloul, KA; Curr. Biol., DOI://10.1016/j.cub.2019.07.014 (2019)
- Transcriptional Bursting and Co-bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility Stavreva, DA; Garcia, DA; Fettweis, G et al. Mol. Cell, DOI://10.1016/j.molcel.2019.06.042 (2019)
- Pathogenic variants in the AFG3L2 proteolytic domain cause SCA28 through haploinsufficiency and proteostatic stress-driven OMA1 activation Tulli, S; Del Bondio, A; Baderna, V et al. J. Med. Genet., DOI://10.1136/jmedgenet-2018-105766 (2019)
- Histone methyltransferase PRDM9 is not essential for meiosis in male mice Mihola, O; Pratto, F; Brick, K et al. Genome Res., DOI://10.1101/gr.244426.118 (2019)
- CRISPR/Cas9-mediated Knockout and In Situ Inversion of ORF57 Gene from All Copies of The KSHV Genome in BCBL-1 Cells BeltCappellino, A; Majerciak, V; Lobanov, A; Lack, J; Cam, M; Zheng, ZM; J. Virol., DOI://10.1128/JVI.00628-19 (2019)
- Kilquist syndrome: A novel syndromic hearing loss disorder caused by homozygous deletion of SLC12A2 Macnamara, EF; Koehler, AE; D'Souza, P et al. Hum. Mutat., DOI://10.1002/humu.23722 (2019)
- 3' Uridylation Confers miRNAs with Non-canonical Target Repertoires Yang, A; Bofill-De Ros, X; Shao, TJ et al. Mol. Cell, DOI://10.1016/j.molcel.2019.05.014 (2019)
- Pilot Trial of Adoptive Transfer of Chimeric Antigen Receptor-transduced T Cells Targeting EGFRvIII in Patients With Glioblastoma Goff, SL; Morgan, RA; Yang, JC et al. J. Immunother., DOI://10.1097/CJI.0000000000000260 (2019)
- Assignment of virus and antimicrobial resistance genes to microbial hosts in a complex microbial community by combined long-read assembly and proximity ligation Bickhart, DM; Watson, M; Koren, S et al. Genome Biol., DOI://10.1186/s13059-019-1760-x (2019)
- Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells Lee, PH; Yamamoto, TN; Gurusamy, D et al. J. Exp. Med., DOI://10.1084/jem.20181218 (2019)
- Accurate circular consensus long-read sequencing improves variant detection and assembly of a human genome Wenger, AM; Peluso, P; Rowell, WJ et al. Nat. Biotechnol., DOI://10.1038/s41587-019-0217-9 (2019)
- Transcriptome profiling of Plasmodium vivax in Saimiri monkeys identifies potential ligands for invasion Gunalan, K; Sá, JM; Moraes Barros, RR et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1818485116 (2019)
- Fully automated patellofemoral MRI segmentation using holistically nested networks: Implications for evaluating patellofemoral osteoarthritis, pain, injury, pathology, and adolescent development Cheng, R; Alexandridi, NA; Smith, RM et al. Magn Reson Med, DOI://10.1002/mrm.27920 (2019)
- Distinctions among real and apparent respiratory motions in human fMRI data Power, JD; Lynch, CJ; Silver, BM; Dubin, MJ; Martin, A; Jones, RM; Neuroimage, DOI://10.1016/j.neuroimage.2019.116041 (2019)
- Visual temporal frequency preference shows a distinct cortical architecture using fMRI Chai, Y; Handwerker, DA; Marrett, S et al. Neuroimage, DOI://10.1016/j.neuroimage.2019.04.048 (2019)
- The RNA exosome nuclease complex regulates human embryonic stem cell differentiation Belair, C; Sim, S; Kim, KY et al. J. Cell Biol., DOI://10.1083/jcb.201811148 (2019)
- Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation Nagashima, H; Mahlakõiv, T; Shih, HY et al. Immunity, DOI://10.1016/j.immuni.2019.06.009 (2019)
- GATA-2-deficient mast cells limit IgE-mediated immediate hypersensitivity reactions in human subjects Desai, A; Sowerwine, K; Liu, Y et al. J. Allergy Clin. Immunol., DOI://10.1016/j.jaci.2019.05.007 (2019)
- Circulating Lymphangioleiomyomatosis Tumor Cells With Loss of Heterozygosity in the TSC2 Gene Show Increased Aldehyde Dehydrogenase Activity Pacheco-Rodríguez, G; Steagall, WK; Samsel, L et al. Chest, DOI://10.1016/j.chest.2019.03.040 (2019)
- A suite of automated sequence analyses reduces the number of candidate deleterious variants and reveals a difference between probands and unaffected siblings Gu, F; Wu, A; Gordon, MG et al. Genet. Med., DOI://10.1038/s41436-019-0434-0 (2019)
- Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer Lo, W; Parkhurst, M; Robbins, PF et al. Cancer Immunol Res, DOI://10.1158/2326-6066.CIR-18-0686 (2019)
- Novel mutations in CLN6 cause late-infantile neuronal ceroid lipofuscinosis without visual impairment in two unrelated patients Chin, JJ; Behnam, B; Davids, M et al. Mol. Genet. Metab., DOI://10.1016/j.ymgme.2018.12.001 (2019)
- Tumor-infiltrating human CD4+ regulatory T cells display a distinct TCR repertoire and exhibit tumor and neoantigen reactivity Ahmadzadeh, M; Pasetto, A; Jia, L et al. Sci Immunol, DOI://10.1126/sciimmunol.aao4310 (2019)
- Exploring induced pluripotency in human fibroblasts via construction, validation, and application of a gene regulatory network Hamaneh, MB; Yu, YK; PLoS ONE, DOI://10.1371/journal.pone.0220742 (2019)
- Multimodal imaging reveals a complex pattern of dysfunction in corticolimbic pathways in major depressive disorder Nugent, AC; Farmer, C; Evans, JW; Snider, SL; Banerjee, D; Zarate, CA; Hum Brain Mapp, DOI://10.1002/hbm.24679 (2019)
- An insight into the sialome, mialome and virome of the horn fly, Haematobia irritans Ribeiro, JM; Debat, HJ; Boiani, M; Ures, X; Rocha, S; Breijo, M; BMC Genomics, DOI://10.1186/s12864-019-5984-7 (2019)
- Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts Narisu, N; Rothwell, R; Vrtačnik, P et al. Aging Cell, DOI://10.1111/acel.13010 (2019)
- Structures and operating principles of the replisome Gao, Y; Cui, Y; Fox, T et al. Science, DOI://10.1126/science.aav7003 (2019)
- Race-ethnic differences in the associations of maternal lipid trait genetic risk scores with longitudinal fetal growth Ouidir, M; Mendola, P; Workalemahu, T et al. J Clin Lipidol, DOI://10.1016/j.jacl.2019.06.007 (2019)
- The seizure onset zone drives state-dependent epileptiform activity in susceptible brain regions Diamond, JM; Chapeton, JI; Theodore, WH; Inati, SK; Zaghloul, KA; Clin Neurophysiol, DOI://10.1016/j.clinph.2019.05.032 (2019)
- Immune regulation by glucocorticoids can be linked to cell type-dependent transcriptional responses Franco, LM; Gadkari, M; Howe, KN et al. J. Exp. Med., DOI://10.1084/jem.20180595 (2019)
- Subtle predictive movements reveal actions regardless of social context McMahon, EG; Zheng, CY; Pereira, F; Gonzalez, R; Ungerleider, LG; Vaziri-Pashkam, M; J Vis, DOI://10.1167/19.7.16 (2019)
- The Magnitude of IFN-γ Responses Is Fine-Tuned by DNA Architecture and the Non-coding Transcript of Ifng-as1 Petermann, F; Pękowska, A; Johnson, CA et al. Mol. Cell, DOI://10.1016/j.molcel.2019.06.025 (2019)
- Pseudodominance of autoinflammatory disease in a single Turkish family explained by co-inheritance of haploinsufficiency of A20 and familial Mediterranean fever Horita, N; Gül, A; Aksentijevich, I; Kastner, D; Remmers, EF; Clin. Exp. Rheumatol., 0392-856X (2019)
- Engineered Bcor mutations lead to acute leukemia of progenitor B-1 lymphocyte origin in a sensitized background Yin, M; Chung, YJ; Lindsley, RC et al. Blood, DOI://10.1182/blood.2018864173 (2019)
- Discovering new antiretroviral compounds in Big Data chemical space of the SAVI library Savosina, PI; Stolbov, LA; Druzhilovskiy, DS; Filimonov, DA; Nicklaus, MC; Poroikov, VV; Biomed Khim, DOI://10.18097/PBMC20196502073 (2019)
- Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers Parkhurst, MR; Robbins, PF; Tran, E et al. Cancer Discov, DOI://10.1158/2159-8290.CD-18-1494 (2019)
- Eye in a Disk: eyeIntegration Human Pan-Eye and Body Transcriptome Database Version 1.0 Swamy, V; McGaughey, D; Invest. Ophthalmol. Vis. Sci., DOI://10.1167/iovs.19-27106 (2019)
- The transcription factor TCF-1 enforces commitment to the innate lymphoid cell lineage Harly, C; Kenney, D; Ren, G et al. Nat. Immunol., DOI://10.1038/s41590-019-0445-7 (2019)
- Mapping associations between polygenic risks for childhood neuropsychiatric disorders, symptoms of attention deficit hyperactivity disorder, cognition, and the brain Sudre, G; Frederick, J; Sharp, W et al. Mol. Psychiatry, DOI://10.1038/s41380-019-0350-3 (2019)
- Evidence for the interaction of A3 adenosine receptor agonists at the drug-binding site (s) of Human P-glycoprotein (ABCB1) Abel, B; Tosh, DK; Durell, SR et al. Mol. Pharmacol., DOI://10.1124/mol.118.115295 (2019)
- Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization Kong, R; Duan, H; Sheng, Z et al. Cell, DOI://10.1016/j.cell.2019.06.030 (2019)
- Association Between Reduced Brain Glucose Metabolism and Cortical Thickness in Alcoholics: Evidence of Neurotoxicity Tomasi, DG; Wiers, CE; Shokri-Kojori, E et al. Int. J. Neuropsychopharmacol., DOI://10.1093/ijnp/pyz036 (2019)
- Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition Chuang, GY; Zhou, J; Acharya, P et al. Structure, DOI://10.1016/j.str.2018.10.007 (2019)
- A role for the CD38 rs3796863 polymorphism in alcohol and monetary reward: evidence from CD38 knockout mice and alcohol self-administration, [11C]-raclopride binding, and functional MRI in humans Lee, MR; Shin, JH; Deschaine, S et al. Am J Drug Alcohol Abuse, DOI://10.1080/00952990.2019.1638928 (2019)
- Maternal dyslipidemia during early pregnancy and epigenetic ageing of the placenta Shrestha, D; Workalemahu, T; Tekola-Ayele, F; Epigenetics, DOI://10.1080/15592294.2019.1629234 (2019)
- Spatial control of oxygen delivery to three-dimensional cultures alters cancer cell growth and gene expression Wulftange, WJ; Rose, MA; Garmendia-Cedillos, M et al. J. Cell. Physiol., DOI://10.1002/jcp.28665 (2019)
- RNA-seq analysis of the salivary glands and midgut of the Argasid tick Ornithodoros rostratus Araujo, RN; Silva, NCS; Mendes-Sousa, A et al. Sci Rep, DOI://10.1038/s41598-019-42899-z (2019)
- Learning deep similarity metric for 3D MR-TRUS image registration Haskins, G; Kruecker, J; Kruger, U et al. Int J Comput Assist Radiol Surg, DOI://10.1007/s11548-018-1875-7 (2019)
- Blood DNA methylation and breast cancer risk: a meta-analysis of four prospective cohort studies Bodelon, C; Ambatipudi, S; Dugué, PA et al. Breast Cancer Res., DOI://10.1186/s13058-019-1145-9 (2019)
- A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure Sung, YJ; de Las Fuentes, L; Winkler, TW et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddz070 (2019)
- Molecular recognition of nucleosomes by binding partners Kale, S; Goncearenco, A; Markov, Y; Landsman, D; Panchenko, AR; Curr. Opin. Struct. Biol., DOI://10.1016/j.sbi.2019.03.010 (2019)
- Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity Canela, A; Maman, Y; Huang, SN et al. Mol. Cell, DOI://10.1016/j.molcel.2019.04.030 (2019)
- RNA Sequencing in B-Cell Lymphomas Huang, DW; Dawood, M; Johnson, CA; Schmitz, R; Methods Mol. Biol., DOI://10.1007/978-1-4939-9151-8_13 (2019)
- Meta-analysis of GWA studies provides new insights on the genetic architecture of skin pigmentation in recently admixed populations Lona-Durazo, F; Hernandez-Pacheco, N; Fan, S et al. BMC Genet., DOI://10.1186/s12863-019-0765-5 (2019)
- Hair of the Dog: Identification of a Cis-Regulatory Module Predicted to Influence Canine Coat Composition Whitaker, DT; Ostrander, EA; Genes (Basel), DOI://10.3390/genes10050323 (2019)
- Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity Kilpeläinen, TO; Bentley, AR; Noordam, R et al. Nat Commun, DOI://10.1038/s41467-018-08008-w (2019)
- RNA-Seq and protein mass spectrometry in microdissected kidney tubules reveal signaling processes initiating lithium-induced nephrogenic diabetes insipidus Sung, CC; Chen, L; Limbutara, K et al. Kidney Int., DOI://10.1016/j.kint.2019.02.015 (2019)
- Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions de Vries, PS; Brown, MR; Bentley, AR et al. Am. J. Epidemiol., DOI://10.1093/aje/kwz005 (2019)
- Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids Bentley, AR; Sung, YJ; Brown, MR et al. Nat. Genet., DOI://10.1038/s41588-019-0378-y (2019)
- Developments in integrative modeling with dynamical interfaces Ozdemir, ES; Nussinov, R; Gursoy, A; Keskin, O; Curr. Opin. Struct. Biol., DOI://10.1016/j.sbi.2018.10.007 (2019)
- Multiplicative fitness, rapid haplotype discovery, and fitness decay explain evolution of human MHC Lobkovsky, AE; Levi, L; Wolf, YI et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1714436116 (2019)
- Correction: Single cell analysis of adult mouse skeletal muscle stem cells in homeostatic and regenerative conditions (doi: 10.1242/dev.174177) Dell'Orso, S; Juan, AH; Ko, KD et al. Development, DOI://10.1242/dev.181743 (2019)
- Sexual dimorphisms in the transcriptomes of murine salivary glands Mukaibo, T; Gao, X; Yang, NY; Oei, MS; Nakamoto, T; Melvin, JE; FEBS Open Bio, DOI://10.1002/2211-5463.12625 (2019)
- ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response Adeyemo, AA; Zaghloul, NA; Chen, G et al. Nat Commun, DOI://10.1038/s41467-019-10967-7 (2019)
- Structural Insights into α-Synuclein Fibril Polymorphism: Effects of Parkinson's Disease-Related C-Terminal Truncations Ni, X; McGlinchey, RP; Jiang, J; Lee, JC; J. Mol. Biol., DOI://10.1016/j.jmb.2019.07.001 (2019)
- The ribosomal prolyl-hydroxylase OGFOD1 decreases during cardiac differentiation and modulates translation and splicing Stoehr, A; Kennedy, L; Yang, Y et al. JCI Insight, DOI://10.1172/jci.insight.128496 (2019)
- PTM-Logo: a program for generation of sequence logos based on position-specific background amino-acid probabilities Saethang, T; Hodge, K; Yang, CR et al. Bioinformatics, DOI://10.1093/bioinformatics/btz568 (2019)
- Phosphoproteomic Identification of Vasopressin V2 Receptor-Dependent Signaling in the Renal Collecting Duct Deshpande, V; Kao, AR; Raghuram, V; Datta, A; Chou, CL; Knepper, MA; Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00281.2019 (2019)
- Correction: Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression Guo, W; Machado-Vieira, R; Mathew, S et al. Transl Psychiatry, DOI://10.1038/s41398-019-0442-5 (2019)
- Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis Deniset, JF; Belke, D; Lee, WY et al. Immunity, DOI://10.1016/j.immuni.2019.06.010 (2019)
- Pathogenic Autoreactive T and B Cells Cross-React with Mimotopes Expressed by a Common Human Gut Commensal to Trigger Autoimmunity Ruff, WE; Dehner, C; Kim, WJ et al. Cell Host Microbe, DOI://10.1016/j.chom.2019.05.003 (2019)
- Functional interplay between DEAD-box RNA helicases Ded1 and Dbp1 in preinitiation complex attachment and scanning on structured mRNAs in vivo Sen, ND; Gupta, N; K Archer, S; Preiss, T; Lorsch, JR; Hinnebusch, AG; Nucleic Acids Res., DOI://10.1093/nar/gkz595 (2019)
- Parsing neurodevelopmental features of irritability and anxiety: Replication and validation of a latent variable approach Cardinale, EM; Kircanski, K; Brooks, J et al. Dev. Psychopathol., DOI://10.1017/S095457941900035X (2019)
- Chemical genomics reveals histone deacetylases are required for core regulatory transcription Gryder, BE; Wu, L; Woldemichael, GM et al. Nat Commun, DOI://10.1038/s41467-019-11046-7 (2019)
- Avapritinib: A Selective Inhibitor of KIT and PDGFRα that Reverses ABCB1 and ABCG2-Mediated Multidrug Resistance in Cancer Cell Lines Wu, CP; Lusvarghi, S; Wang, JC et al. Mol. Pharm., DOI://10.1021/acs.molpharmaceut.9b00274 (2019)
- BORIS expression in ovarian cancer precursor cells alters the CTCF cistrome and enhances invasiveness through GALNT14 Hillman, JC; Pugacheva, EM; Barger, CJ et al. Mol. Cancer Res., DOI://10.1158/1541-7786.MCR-19-0310 (2019)
- Cancer-testis antigens as biomarkers for Merkel cell carcinoma: Pitfalls and opportunities Dasgeb, B; Mehregan, D; Ring, C; Nartker, N; Brownell, I; J. Cutan. Pathol., DOI://10.1111/cup.13528 (2019)
- The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons Seah, MKY; Wang, Y; Goy, PA et al. Development, DOI://10.1242/dev.170266 (2019)
- Maternal Exposure to Non-nutritive Sweeteners Impacts Progeny's Metabolism and Microbiome Olivier-Van Stichelen, S; Rother, KI; Hanover, JA; Front Microbiol, DOI://10.3389/fmicb.2019.01360 (2019)
- Plerixafor for the Treatment of WHIM Syndrome McDermott, DH; Pastrana, DV; Calvo, KR et al. N. Engl. J. Med., DOI://10.1056/NEJMoa1808575 (2019)
- Impact of APOL1 Genetic Variants on HIV-1 Infection and Disease Progression An, P; Kirk, GD; Limou, S; Binns-Roemer, E; Kopp, JB; Winkler, CA; Front Immunol, DOI://10.3389/fimmu.2019.00053 (2019)
- Amino-acid inserts of HIV-1 capsid (CA) induce CA degradation and abrogate viral infectivity: Insights for the dynamics and mechanisms of HIV-1 CA decomposition Amano, M; Bulut, H; Tamiya, S; Nakamura, T; Koh, Y; Mitsuya, H; Sci Rep, DOI://10.1038/s41598-019-46082-2 (2019)
- Cholesterol-Dependent Bending Energy Is Important in Cholesterol Distribution of the Plasma Membrane Allender, DW; Sodt, AJ; Schick, M; Biophys. J., DOI://10.1016/j.bpj.2019.03.028 (2019)
- Effects of Ketamine on Brain Activity During Emotional Processing: Differential Findings in Depressed Versus Healthy Control Participants Reed, JL; Nugent, AC; Furey, ML; Szczepanik, JE; Evans, JW; Zarate, CA; Biol Psychiatry Cogn Neurosci Neuroimaging, DOI://10.1016/j.bpsc.2019.01.005 (2019)
- Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection Yao, C; Sun, HW; Lacey, NE et al. Nat. Immunol., DOI://10.1038/s41590-019-0403-4 (2019)
- Novel Heterozygous Variants in KMT2D Associated with Holoprosencephaly Tekendo-Ngongang, C; Kruszka, P; Martinez, AF; Muenke, M; Clin. Genet., DOI://10.1111/cge.13598 (2019)
- Deep neural network predicts emotional responses of the human brain from functional magnetic resonance imaging Kim, HC; Bandettini, PA; Lee, JH; Neuroimage, DOI://10.1016/j.neuroimage.2018.10.054 (2019)
- A critical review of five machine learning-based algorithms for predicting protein stability changes upon mutation Fang, J Brief. Bioinformatics, DOI://10.1093/bib/bbz071 (2019)
- A Genome-Wide Epstein-Barr Virus Polyadenylation Map and Its Antisense RNA to EBNA Majerciak, V; Yang, W; Zheng, J; Zhu, J; Zheng, ZM; J. Virol., DOI://10.1128/JVI.01593-18 (2019)
- Interactions of Water and Alkanes: Modifying Additive Force Fields to Account for Polarization Effects Krämer, A; Pickard, FC; Huang, J et al. J Chem Theory Comput, DOI://10.1021/acs.jctc.9b00016 (2019)
- CPF Recruitment to Non-canonical Transcription Termination Sites Triggers Heterochromatin Assembly and Gene Silencing Vo, TV; Dhakshnamoorthy, J; Larkin, M et al. Cell Rep, DOI://10.1016/j.celrep.2019.05.107 (2019)
- Author Correction: Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis Vogt, EJ; Tokuhiro, K; Guo, M et al. Nat Commun, DOI://10.1038/s41467-019-10935-1 (2019)
- The structure-activity profile of mercaptobenzamides' anti-HIV activity suggests that thermodynamics of metabolism is more important than binding affinity to the target Nikolayevskiy, H; Robello, M; Scerba, MT et al. Eur J Med Chem, DOI://10.1016/j.ejmech.2019.06.020 (2019)
- Large-scale purification of functional human P-glycoprotein (ABCB1) Nandigama, K; Lusvarghi, S; Shukla, S; Ambudkar, SV; Protein Expr. Purif., DOI://10.1016/j.pep.2019.03.002 (2019)
- De novo assembly of the goldfish (Carassius auratus) genome and the evolution of genes after whole-genome duplication Chen, Z; Omori, Y; Koren, S et al. Sci Adv, DOI://10.1126/sciadv.aav0547 (2019)
- Molecular dissection of cone photoreceptor-enriched genes encoding transmembrane and secretory proteins Papal, S; Monti, CE; Tennison, ME; Swaroop, A; J. Neurosci. Res., DOI://10.1002/jnr.24329 (2019)
- Transposable element insertions in fission yeast drive adaptation to environmental stress Esnault, C; Lee, M; Ham, C; Levin, HL; Genome Res., DOI://10.1101/gr.239699.118 (2019)
- The splicing factor U2AF1 contributes to cancer progression through a noncanonical role in translation regulation Palangat, M; Anastasakis, DG; Fei, DL et al. Genes Dev., DOI://10.1101/gad.319590.118 (2019)
- RASA2 and NF1; two-negative regulators of Ras with complementary functions in melanoma Arafeh, R; Di Pizio, A; Elkahloun, AG; Dym, O; Niv, MY; Samuels, Y; Oncogene, DOI://10.1038/s41388-018-0578-4 (2019)
- Maternal BMI-Increasing Genetic Risk Score and Fetal Weights among Diverse US Ethnic Groups Shrestha, D; Rahman, ML; Hinkle, SN; Workalemahu, T; Tekola-Ayele, F; Obesity (Silver Spring), DOI://10.1002/oby.22499 (2019)
- Author Correction: Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration Ratnapriya, R; Sosina, OA; Starostik, MR et al. Nat. Genet., DOI://10.1038/s41588-019-0430-y (2019)
- Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP Li, M; Wang, Y; Banerjee, R et al. Elife, DOI://10.7554/eLife.47060 (2019)
- Induced Chromosomal Aneuploidy Results in Global and Consistent Deregulation of the Transcriptome of Cancer Cells Wangsa, D; Braun, R; Stuelten, CH et al. Neoplasia, DOI://10.1016/j.neo.2019.04.009 (2019)
- Sodium valproate rescues expression of TRANK1 in iPSC-derived neural cells that carry a genetic variant associated with serious mental illness Jiang, X; Detera-Wadleigh, SD; Akula, N et al. Mol. Psychiatry, DOI://10.1038/s41380-018-0207-1 (2019)
- Deep learning-based muscle segmentation and quantification at abdominal CT: application to a longitudinal adult screening cohort for sarcopenia assessment Graffy, PM; Liu, J; Pickhardt, PJ; Burns, JE; Yao, J; Summers, RM; Br J Radiol, DOI://10.1259/bjr.20190327 (2019)
- A parameterized digital 3D model of the Rhesus macaque face for investigating the visual processing of social cues Murphy, AP; Leopold, DA; J. Neurosci. Methods, DOI://10.1016/j.jneumeth.2019.06.001 (2019)
- Association of Step Volume and Intensity With All-Cause Mortality in Older Women Lee, IM; Shiroma, EJ; Kamada, M; Bassett, DR; Matthews, CE; Buring, JE; JAMA Intern Med, DOI://10.1001/jamainternmed.2019.0899 (2019)
- Small posterior fossa in Chiari I malformation affected families is significantly linked to 1q43-44 and 12q23-24.11 using whole exome sequencing Musolf, AM; Ho, WSC; Long, KA et al. Eur. J. Hum. Genet., DOI://10.1038/s41431-019-0457-7 (2019)
- Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals Noordam, R; Young, WJ; Salman, R et al. J. Am. Coll. Cardiol., DOI://10.1016/j.jacc.2019.03.519 (2019)
- The Impact of Anthelmintic Treatment on Human Gut Microbiota Based on Cross-Sectional and Pre- and Postdeworming Comparisons in Western Kenya Easton, AV; Quiñones, M; Vujkovic-Cvijin, I et al. MBio, DOI://10.1128/mBio.00519-19 (2019)
- Novel Inter-omic Analysis Reveals Relationships Between Diverse Gut Microbiota and Host Immune Dysregulation in HLA-B27-Induced Experimental Spondyloarthritis Gill, T; Brooks, SR; Rosenbaum, JT; Asquith, M; Colbert, RA; , DOI://10.1002/art.41018 (2019)
- Agouti-Related Protein 2 Is a New Player in the Teleost Stress Response System Shainer, I; Michel, M; Marquart, GD et al. Curr. Biol., DOI://10.1016/j.cub.2019.05.021 (2019)
- Aberrant expression of select piRNA-pathway genes does not reactivate piRNA silencing in cancer cells Genzor, P; Cordts, SC; Bokil, NV; Haase, AD; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1904498116 (2019)
- Disordered RNA chaperones can enhance nucleic acid folding via local charge screening Holmstrom, ED; Liu, Z; Nettels, D; Best, RB; Schuler, B; Nat Commun, DOI://10.1038/s41467-019-10356-0 (2019)
- Long-Range RNA Structural Information via a Paramagnetically Tagged Reporter Protein Strickland, M; Catazaro, J; Rajasekaran, R et al. J. Am. Chem. Soc., DOI://10.1021/jacs.8b11384 (2019)
- Lysosomal Storage and Albinism Due to Effects of a De Novo CLCN7 Variant on Lysosomal Acidification Nicoli, ER; Weston, MR; Hackbarth, M et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2019.04.008 (2019)
- Aicardi-Goutières syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast cancer Deasy, SK; Uehara, R; Vodnala, SK et al. PLoS Genet., DOI://10.1371/journal.pgen.1008020 (2019)
- One-carbon metabolism gene polymorphisms are associated with cognitive trajectory among African-American adults Beydoun, MA; Tajuddin, SM; Shaked, D; Beydoun, HA; Evans, MK; Zonderman, AB; Neurobiol. Aging, DOI://10.1016/j.neurobiolaging.2019.05.013 (2019)
- Structural Basis of p97 Inhibition by the Site-Selective Anticancer Compound CB-5083 Tang, WK; Odzorig, T; Jin, W; Xia, D; Mol. Pharmacol., DOI://10.1124/mol.118.114256 (2019)
- Fully automated prostate whole gland and central gland segmentation on MRI using holistically nested networks with short connections Cheng, R; Lay, N; Roth, HR et al. J Med Imaging (Bellingham), DOI://10.1117/1.JMI.6.2.024007 (2019)
- Correlation between Disease Severity and the Intestinal Microbiome in Mycobacterium tuberculosis-Infected Rhesus Macaques Namasivayam, S; Kauffman, KD; McCulloch, JA et al. MBio, DOI://10.1128/mBio.01018-19 (2019)
- Smartphone Level Test Measures Disability in Several Neurological Domains for Patients With Multiple Sclerosis Boukhvalova, AK; Fan, O; Weideman, AM et al. Front Neurol, DOI://10.3389/fneur.2019.00358 (2019)
- Integrating multiple biomarkers to increase sensitivity for the detection of Onchocerca volvulus infection Bennuru, S; Oduro-Boateng, G; Osigwe, C et al. J. Infect. Dis., DOI://10.1093/infdis/jiz307 (2019)
- Neutrophil Subsets, Platelets, and Vascular Disease in Psoriasis Teague, HL; Varghese, NJ; Tsoi, LC et al. JACC Basic Transl Sci, DOI://10.1016/j.jacbts.2018.10.008 (2019)
- Efficacy of different dynamic functional connectivity methods to capture cognitively relevant information Xie, H; Zheng, CY; Handwerker, DA et al. Neuroimage, DOI://10.1016/j.neuroimage.2018.12.037 (2019)
- TPMCalculator: one-step software to quantify mRNA abundance of genomic features Vera Alvarez, R; Pongor, LS; Mariño-Ramírez, L; Landsman, D; Bioinformatics, DOI://10.1093/bioinformatics/bty896 (2019)
- The structural basis for Ras activation of PI3Kα lipid kinase Zhang, M; Jang, H; Nussinov, R; Phys Chem Chem Phys, DOI://10.1039/c9cp00101h (2019)
- A chromosome-scale assembly of the major African malaria vector Anopheles funestus Ghurye, J; Koren, S; Small, ST et al. Gigascience, DOI://10.1093/gigascience/giz063 (2019)
- Extensive Heterogeneity and Intrinsic Variation in Spatial Genome Organization Finn, EH; Pegoraro, G; Brandão, HB et al. Cell, DOI://10.1016/j.cell.2019.01.020 (2019)
- Methylphenidate's effects on thalamic metabolism and functional connectivity in cannabis abusers and healthy controls Demiral, ŞB; Tomasi, D; Wiers, CE et al. Neuropsychopharmacology, DOI://10.1038/s41386-018-0287-2 (2019)
- Neighbourhood disadvantage and depressive symptoms among adolescents followed into emerging adulthood Goldstein, RB; Lee, AK; Haynie, DL et al. J Epidemiol Community Health, DOI://10.1136/jech-2018-212004 (2019)
- Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes Zubcevic, L; Hsu, AL; Borgnia, MJ; Lee, SY; Elife, DOI://10.7554/eLife.45779 (2019)
- Methods for Discovering and Targeting Druggable Protein-Protein Interfaces and Their Application to Repurposing Ozdemir, ES; Halakou, F; Nussinov, R; Gursoy, A; Keskin, O; Methods Mol. Biol., DOI://10.1007/978-1-4939-8955-3_1 (2019)
- The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription Malik, N; Yan, H; Moshkovich, N et al. Nat Commun, DOI://10.1038/s41467-019-10102-6 (2019)
- Remarkable Rigidity of the Single α-Helical Domain of Myosin-VI As Revealed by NMR Spectroscopy Barnes, CA; Shen, Y; Ying, J et al. J. Am. Chem. Soc., DOI://10.1021/jacs.9b03116 (2019)
- An integrative Bayesian approach to matrix-based analysis in neuroimaging Chen, G; Bürkner, PC; Taylor, PA et al. Hum Brain Mapp, DOI://10.1002/hbm.24686 (2019)
- Crystal Structure of Bacterial Cytochrome bc1 in Complex with Azoxystrobin Reveals a Conformation Switch of the Rieske Iron-Sulfur Protein Subunit Esser, L; Zhou, F; Yu, CA; Xia, D; J. Biol. Chem., DOI://10.1074/jbc.RA119.008381 (2019)
- Aberrant Clonal Hematopoiesis following Lentiviral Vector Transduction of HSPCs in a Rhesus Macaque Espinoza, DA; Fan, X; Yang, D et al. Mol. Ther., DOI://10.1016/j.ymthe.2019.04.003 (2019)
- Mechanisms of Calcium Leak from Cardiac Sarcoplasmic Reticulum Revealed by Statistical Mechanics Maltsev, AV; Stern, MD; Maltsev, VA; Biophys. J., DOI://10.1016/j.bpj.2019.04.031 (2019)
- REC114 Partner ANKRD31 Controls Number, Timing, and Location of Meiotic DNA Breaks Boekhout, M; Karasu, ME; Wang, J et al. Mol. Cell, DOI://10.1016/j.molcel.2019.03.023 (2019)
- Mucosal vaccine efficacy against intrarectal SHIV is independent of anti-Env antibody response Sui, Y; Lewis, GK; Wang, Y et al. J. Clin. Invest., DOI://10.1172/JCI122110 (2019)
- Layer-specific activation of sensory input and predictive feedback in the human primary somatosensory cortex Yu, Y; Huber, L; Yang, J et al. Sci Adv, DOI://10.1126/sciadv.aav9053 (2019)
- Opportunistic Osteoporosis Screening at Routine Abdominal and Thoracic CT: Normative L1 Trabecular Attenuation Values in More than 20 000 Adults Jang, S; Graffy, PM; Ziemlewicz, TJ; Lee, SJ; Summers, RM; Pickhardt, PJ; Radiology, DOI://10.1148/radiol.2019181648 (2019)
- Regulatory switch at the cytoplasmic interface controls TRPV channel gating Zubcevic, L; Borschel, WF; Hsu, AL; Borgnia, MJ; Lee, SY; Elife, DOI://10.7554/eLife.47746 (2019)
- Biallelic HEPHL1 variants impair ferroxidase activity and cause an abnormal hair phenotype Sharma, P; Reichert, M; Lu, Y et al. PLoS Genet., DOI://10.1371/journal.pgen.1008143 (2019)
- Heterogeneity in refractory acute myeloid leukemia Horibata, S; Gui, G; Lack, J; DeStefano, CB; Gottesman, MM; Hourigan, CS; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1902375116 (2019)
- The relapsing fever spirochete Borrelia turicatae persists in the highly oxidative environment of its soft-bodied tick vector Bourret, TJ; Boyle, WK; Zalud, AK; Valenzuela, JG; Oliveira, F; Lopez, JE; Cell. Microbiol., DOI://10.1111/cmi.12987 (2019)
- The skin transcriptome in hidradenitis suppurativa uncovers an antimicrobial and sweat gland gene signature which has distinct overlap with wounded skin Coates, M; Mariottoni, P; Corcoran, DL et al. PLoS ONE, DOI://10.1371/journal.pone.0216249 (2019)
- Atomic resolution cryo-EM structure of a native-like CENP-A nucleosome aided by an antibody fragment Zhou, BR; Yadav, KNS; Borgnia, M et al. Nat Commun, DOI://10.1038/s41467-019-10247-4 (2019)
- A Suite of Therapeutically-Inspired Nucleic Acid Logic Systems for Conditional Generation of Single-Stranded and Double-Stranded Oligonucleotides Zakrevsky, P; Bindewald, E; Humbertson, H; Viard, M; Dorjsuren, N; Shapiro, BA; Nanomaterials (Basel), DOI://10.3390/nano9040615 (2019)
- XL-DNase-seq: improved footprinting of dynamic transcription factors Oh, KS; Ha, J; Baek, S; Sung, MH; Epigenetics Chromatin, DOI://10.1186/s13072-019-0277-6 (2019)
- Potential Regulatory Role of Competitive Encounter Complexes in Paralogous Phosphotransferase Systems Strickland, M; Kale, S; Strub, MP et al. J. Mol. Biol., DOI://10.1016/j.jmb.2019.04.040 (2019)
- Apparent diffusion coefficient changes in human brain during sleep - Does it inform on the existence of a glymphatic system Demiral, ŞB; Tomasi, D; Sarlls, J et al. Neuroimage, DOI://10.1016/j.neuroimage.2018.10.043 (2019)
- Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium Kobayashi, T; Voisin, B; Kim, DY et al. Cell, DOI://10.1016/j.cell.2018.12.031 (2019)
- Artificial intelligence at the intersection of pathology and radiology in prostate cancer Harmon, SA; Tuncer, S; Sanford, T; Choyke, PL; Türkbey, B; Diagn Interv Radiol, DOI://10.5152/dir.2019.19125 (2019)
- Neocortical Projection Neurons Instruct Inhibitory Interneuron Circuit Development in a Lineage-Dependent Manner Wester, JC; Mahadevan, V; Rhodes, CT et al. Neuron, DOI://10.1016/j.neuron.2019.03.036 (2019)
- The oral microbiome of patients undergoing treatment for severe aplastic anemia: a pilot study Ames, NJ; Barb, JJ; Ranucci, A et al. Ann. Hematol., DOI://10.1007/s00277-019-03599-w (2019)
- eNetXplorer: an R package for the quantitative exploration of elastic net families for generalized linear models Candia, J; Tsang, JS; BMC Bioinformatics, DOI://10.1186/s12859-019-2778-5 (2019)
- Nucleosome spacing periodically modulates nucleosome chain folding and DNA topology in circular nucleosome arrays Bass, MV; Nikitina, T; Norouzi, D; Zhurkin, VB; Grigoryev, SA; J. Biol. Chem., DOI://10.1074/jbc.RA118.006412 (2019)
- The Transcriptome of the Salivary Glands of Amblyomma aureolatum Reveals the Antimicrobial Peptide Microplusin as an Important Factor for the Tick Protection Against Rickettsia rickettsii Infection Martins, LA; Malossi, CD; Galletti, MFBM et al. Front Physiol, DOI://10.3389/fphys.2019.00529 (2019)
- TFE3 Xp11.2 Translocation Renal Cell Carcinoma Mouse Model Reveals Novel Therapeutic Targets and Identifies GPNMB as a Diagnostic Marker for Human Disease Baba, M; Furuya, M; Motoshima, T et al. Mol. Cancer Res., DOI://10.1158/1541-7786.MCR-18-1235 (2019)
- Whole-Genome Sequences of Salmonella enterica Serovar I 4,[5],12:i:- Isolates from Swine Gonzalez, S; Harvey, RB; Scott, HM et al. Microbiol Resour Announc, DOI://10.1128/MRA.00223-19 (2019)
- A Frizzled-Like Cysteine-Rich Domain in Glypican-3 Mediates Wnt Binding and Regulates Hepatocellular Carcinoma Tumor Growth in Mice Li, N; Wei, L; Liu, X et al. Hepatology, DOI://10.1002/hep.30646 (2019)
- Maternal and Offspring Genetic Risk of Type 2 Diabetes and Offspring Birthweight Among African Ancestry Populations Rahman, ML; Shrestha, D; Workalemahu, T et al. J. Clin. Endocrinol. Metab., DOI://10.1210/jc.2018-02756 (2019)
- Equitable Thresholding and Clustering (ETAC): A novel method for FMRI clustering in AFNI Cox, RW Brain Connect, DOI://10.1089/brain.2019.0666 (2019)
- Evaluating corrections for Eddy-currents and other EPI distortions in diffusion MRI: methodology and a dataset for benchmarking Irfanoglu, MO; Sarlls, J; Nayak, A; Pierpaoli, C; Magn Reson Med, DOI://10.1002/mrm.27577 (2019)
- Banana (Musa acuminata) transcriptome profiling in response to rhizobacteria: Bacillus amyloliquefaciens Bs006 and Pseudomonas fluorescens Ps006 Gamez, RM; Rodríguez, F; Vidal, NM et al. BMC Genomics, DOI://10.1186/s12864-019-5763-5 (2019)
- Data-driven inference of hidden nodes in networks Hoang, DT; Jo, J; Periwal, V; Phys Rev E, DOI://10.1103/PhysRevE.99.042114 (2019)
- Identifying Small Proteins by Ribosome Profiling with Stalled Initiation Complexes Weaver, J; Mohammad, F; Buskirk, AR; Storz, G; MBio, DOI://10.1128/mBio.02819-18 (2019)
- Epigenetic regulation of REX1 expression and chromatin binding specificity by HMGNs Zhang, S; Deng, T; Tang, W et al. Nucleic Acids Res., DOI://10.1093/nar/gkz161 (2019)
- Early-childhood social reticence predicts SCR-BOLD coupling during fear extinction recall in preadolescent youth Michalska, KJ; Feldman, JS; Ivie, EJ et al. Dev Cogn Neurosci, DOI://10.1016/j.dcn.2018.12.003 (2019)
- miR-155 harnesses Phf19 to potentiate cancer immunotherapy through epigenetic reprogramming of CD8+ T cell fate Ji, Y; Fioravanti, J; Zhu, W et al. Nat Commun, DOI://10.1038/s41467-019-09882-8 (2019)
- Physical Activity Patterns and Mortality: The Weekend Warrior and Activity Bouts Shiroma, EJ; Lee, IM; Schepps, MA; Kamada, M; Harris, TB; Med Sci Sports Exerc, DOI://10.1249/MSS.0000000000001762 (2019)
- Defective IgA response to atypical intestinal commensals in IL-21 receptor deficiency reshapes immune cell homeostasis and mucosal immunity Cho, H; Jaime, H; de Oliveira, RP et al. Mucosal Immunol, DOI://10.1038/s41385-018-0056-x (2019)
- Heritability and genetic variance of dementia with Lewy bodies Guerreiro, R; Escott-Price, V; Hernandez, DG et al. Neurobiol. Dis., DOI://10.1016/j.nbd.2019.04.004 (2019)
- Differential Brain Mechanisms of Selection and Maintenance of Information during Working Memory Quentin, R; King, JR; Sallard, E et al. J. Neurosci., DOI://10.1523/JNEUROSCI.2764-18.2019 (2019)
- High dimensional mediation analysis with latent variables Derkach, A; Pfeiffer, RM; Chen, TH; Sampson, JN; Biometrics, DOI://10.1111/biom.13053 (2019)
- Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting Cheng, C; Xu, K; Kong, R et al. PLoS ONE, DOI://10.1371/journal.pone.0215163 (2019)
- Integrated Genomic and Functional microRNA Analysis Identifies miR-30-5p as a Tumor Suppressor and Potential Therapeutic Nanomedicine in Head and Neck Cancer Saleh, AD; Cheng, H; Martin, SE et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-0716 (2019)
- Computation-guided analysis of paroxetine binding to hSERT reveals functionally important structural elements and dynamics Abramyan, AM; Slack, RD; Meena, S et al. Neuropharmacology, DOI://10.1016/j.neuropharm.2018.10.040 (2019)
- Frontal alpha asymmetry moderates the relations between behavioral inhibition and social-effect ERN Harrewijn, A; Buzzell, GA; Debnath, R; Leibenluft, E; Pine, DS; Fox, NA; Biol Psychol, DOI://10.1016/j.biopsycho.2018.12.014 (2019)
- Characterization of the Phosphorylation Site of GRTH/DDX25 and Protein Kinase A Binding Interface Provides Structural Basis for the Design of a Non-Hormonal Male Contraceptive Raju, M; Hassan, SA; Kavarthapu, R; Anbazhagan, R; Dufau, ML; Sci Rep, DOI://10.1038/s41598-019-42857-9 (2019)
- Identification of Neoantigen-Reactive Tumor-Infiltrating Lymphocytes in Primary Bladder Cancer Leko, V; McDuffie, LA; Zheng, Z et al. J. Immunol., DOI://10.4049/jimmunol.1801022 (2019)
- Assessing the Role of 98 Established Loci for BMI in American Indians Muller, YL; Hanson, RL; Piaggi, P et al. Obesity (Silver Spring), DOI://10.1002/oby.22433 (2019)
- A Rapid Form of Offline Consolidation in Skill Learning Bönstrup, M; Iturrate, I; Thompson, R; Cruciani, G; Censor, N; Cohen, LG; Curr. Biol., DOI://10.1016/j.cub.2019.02.049 (2019)
- Whole genome sequencing of canids reveals genomic regions under selection and variants influencing morphology Plassais, J; Kim, J; Davis, BW et al. Nat Commun, DOI://10.1038/s41467-019-09373-w (2019)
- Molecular constraints on CDR3 for thymic selection of MHC-restricted TCRs from a random pre-selection repertoire Lu, J; Van Laethem, F; Bhattacharya, A et al. Nat Commun, DOI://10.1038/s41467-019-08906-7 (2019)
- An African-specific haplotype in MRGPRX4 is associated with menthol cigarette smoking Kozlitina, J; Risso, D; Lansu, K et al. PLoS Genet., DOI://10.1371/journal.pgen.1007916 (2019)
- Evolution of All-Atom Protein Force Fields to Improve Local and Global Properties Zerze, GH; Zheng, W; Best, RB; Mittal, J; J Phys Chem Lett, DOI://10.1021/acs.jpclett.9b00850 (2019)
- The mechanism of PI3Kα activation at the atomic level Zhang, M; Jang, H; Nussinov, R; Chem Sci, DOI://10.1039/c8sc04498h (2019)
- Design and in Vivo Characterization of A1 Adenosine Receptor Agonists in the Native Ribose and Conformationally Constrained (N)-Methanocarba Series Tosh, DK; Rao, H; Bitant, A et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.8b01662 (2019)
- Association Between Childhood Anhedonia and Alterations in Large-Scale Resting-State Networks and Task-Evoked Activation Pornpattananangkul, N; Leibenluft, E; Pine, DS; Stringaris, A; JAMA Psychiatry, DOI://10.1001/jamapsychiatry.2019.0020 (2019)
- SOX2