Papers that used NIH HPC Systems resources

Papers that used NIH HPC (Biowulf) resources

If you have published research that has made significant use of these systems, please let us know by sending email to staff@hpc.nih.gov

2022 to date (2 papers)

Autocrine vitamin D signaling switches off pro-inflammatory programs of T H 1 cells Chauss, D; Freiwald, T; McGregor, R et al. Nat Immunol, DOI://10.1038/s41590-021-01080-3 (2022)
Antipsychotic medication-mediated cognitive change in schizophrenia and polygenic score for cognitive ability Blackman, RK; Dickinson, D; Eisenberg, DP et al. Schizophr Res Cogn, DOI://10.1016/j.scog.2021.100223 (2022)

2021 (449 papers)

Comprehensive multiomic characterization of human papillomavirus-driven recurrent respiratory papillomatosis reveals distinct molecular subtypes Sievers, C; Robbins, Y; Bai, K et al. Commun Biol, DOI://10.1038/s42003-021-02942-0 (2021)
Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma Lu, X; Sabbasani, VR; Osei-Amponsa, V et al. Nat Commun, DOI://10.1038/s41467-021-27570-4 (2021)
Nuclear pore protein NUP210 depletion suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response Amin, R; Shukla, A; Zhu, JJ et al. Nat Commun, DOI://10.1038/s41467-021-27451-w (2021)
Identification of Genetic Risk Factors for Familial Urinary Bladder Cancer: An Exome Sequencing Study Pemov, A; Wegman-Ostrosky, T; Kim, J et al. JCO Precis Oncol, DOI://10.1200/PO.21.00115 (2021)
A machine learning model for ranking candidate HLA class I neoantigens based on known neoepitopes from multiple human tumor types Gartner, JJ; Parkhurst, MR; Gros, A et al. Nat Cancer, DOI://10.1038/s43018-021-00197-6 (2021)
gcMECM: graph clustering of mutual exclusivity of cancer mutations Hu, Y; Yan, C; Chen, Q; Meerzaman, D; , BMC Bioinformatics, DOI://10.1186/s12859-021-04505-w (2021)

Lentzeacins A-E, New Bacterial-Derived 2,5- and 2,6-Disubstituted Pyrazines from a BGC-Rich Soil Bacterium Lentzea sp. GA3-008 Liu, HB; Davison, JR; Rajwani, R et al. Molecules, DOI://10.3390/molecules26237197 (2021)
The Hydrogen-Coupled Oligopeptide Membrane Cotransporter Pept2 is SUMOylated in Kidney Distal Convoluted Tubule Cells Aroankins, TS; Murali, SK; Fenton, RA; Wu, Q; , Front Mol Biosci, DOI://10.3389/fmolb.2021.790606 (2021)
Immuno-transcriptomic profiling of extracranial pediatric solid malignancies Brohl, AS; Sindiri, S; Wei, JS et al. Cell Rep, DOI://10.1016/j.celrep.2021.110047 (2021)
Inferred expression regulator activities suggest genes mediating cardiometabolic genetic signals Hoskins, JW; Chung, CC; O'Brien, A et al. PLoS Comput Biol, DOI://10.1371/journal.pcbi.1009563 (2021)
Single-nucleus transcriptomic analysis of human dorsal root ganglion neurons Nguyen, MQ; von Buchholtz, LJ; Reker, AN et al. Elife, DOI://10.7554/eLife.71752 (2021)
Multiview confocal super-resolution microscopy Wu, Y; Han, X; Su, Y et al. Nature, DOI://10.1038/s41586-021-04110-0 (2021)

Genome-Guided Discovery of Natural Products through Multiplexed Low-Coverage Whole-Genome Sequencing of Soil Actinomycetes on Oxford Nanopore Flongle Rajwani, R; Ohlemacher, SI; Zhao, G et al. mSystems, DOI://10.1128/mSystems.01020-21 (2021)
Cataloging Human PRDM9 Allelic Variation Using Long-Read Sequencing Reveals PRDM9 Population Specificity and Two Distinct Groupings of Related Alleles Alleva, B; Brick, K; Pratto, F et al. Front Cell Dev Biol, DOI://10.3389/fcell.2021.675286 (2021)
Integration of adeno-associated virus (AAV) into the genomes of most Thai and Mongolian liver cancer patients does not induce oncogenesis Schäffer, AA; Dominguez, DA; Chapman, LM et al. BMC Genomics, DOI://10.1186/s12864-021-08098-9 (2021)
Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfaces Lee, M; Changela, A; Gorman, J et al. Nat Commun, DOI://10.1038/s41467-021-26579-z (2021)
Whole genome and exome sequencing reference datasets from a multi-center and cross-platform benchmark study Zhao, Y; Fang, LT; Shen, TW et al. Sci Data, DOI://10.1038/s41597-021-01077-5 (2021)
Overcoming Acquired Epigenetic Resistance to BTK Inhibitors Shaffer, AL; Phelan, JD; Wang, JQ et al. Blood Cancer Discov, DOI://10.1158/2643-3230.BCD-21-0063 (2021)

CSC software corrects off-target mediated gRNA depletion in CRISPR-Cas9 essentiality screens Perez, AR; Sala, L; Perez, RK; Vidigal, JA; , Nat Commun, DOI://10.1038/s41467-021-26722-w (2021)
A large Canadian cohort provides insights into the genetic architecture of human hair colour Lona-Durazo, F; Mendes, M; Thakur, R et al. Commun Biol, DOI://10.1038/s42003-021-02764-0 (2021)
Genome-scale metabolic modeling reveals SARS-CoV-2-induced metabolic changes and antiviral targets Cheng, K; Martin-Sancho, L; Pal, LR et al. Mol Syst Biol, DOI://10.15252/msb.202110260 (2021)
PERK signaling through C/EBPδ contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cells Sheshadri, N; Poria, DK; Sharan, S et al. Cell Death Dis, DOI://10.1038/s41419-021-04318-y (2021)
Placental Gene Co-expression Network for Maternal Plasma Lipids Revealed Enrichment of Inflammatory Response Pathways Ouidir, M; Chatterjee, S; Mendola, P et al. Front Genet, DOI://10.3389/fgene.2021.681095 (2021)
Methylphenidate modulates interactions of anxiety with cognition Gaillard, C; Lago, TR; Gorka, AX et al. Transl Psychiatry, DOI://10.1038/s41398-021-01621-2 (2021)

A 584 bp deletion in CTRB2 inhibits chymotrypsin B2 activity and secretion and confers risk of pancreatic cancer Jermusyk, A; Zhong, J; Connelly, KE et al. Am J Hum Genet, DOI://10.1016/j.ajhg.2021.09.002 (2021)
Development of CHARMM Additive Potential Energy Parameters for α-Methyl Amino Acids Pane, AJ; Yu, W; Aytenfisu, A et al. J Phys Chem B, DOI://10.1021/acs.jpcb.1c07202 (2021)
Identification of BvgA-Dependent and BvgA-Independent Small RNAs (sRNAs) in Bordetella pertussis Using the Prokaryotic sRNA Prediction Toolkit ANNOgesic Moon, K; Sim, M; Tai, CH et al. Microbiol Spectr, DOI://10.1128/Spectrum.00044-21 (2021)
Cigarette Smoking and Opium Use in Relation to the Oral Microbiota in Iran Wu, Z; Han, Y; Caporaso, JG et al. Microbiol Spectr, DOI://10.1128/Spectrum.00138-21 (2021)
T Cell-Mediated Antitumor Immunity Cooperatively Induced By TGFβR1 Antagonism and Gemcitabine Counteracts Reformation of the Stromal Barrier in Pancreatic Cancer Li, D; Schaub, N; Guerin, TM et al. Mol Cancer Ther, DOI://10.1158/1535-7163.MCT-20-0620 (2021)
A disease-specific language representation model for cerebrovascular disease research Lin, CH; Hsu, KC; Liang, CK et al. Comput Methods Programs Biomed, DOI://10.1016/j.cmpb.2021.106446 (2021)

Tyrp1 Mutant Variants Associated with OCA3: Computational Characterization of Protein Stability and Ligand Binding Patel, MH; Dolinska, MB; Sergeev, YV; , Int J Mol Sci, DOI://10.3390/ijms221910203 (2021)
Repeated strand invasion and extensive branch migration are hallmarks of meiotic recombination Ahuja, JS; Harvey, CS; Wheeler, DL; Lichten, M; , Mol Cell, DOI://10.1016/j.molcel.2021.08.003 (2021)
Sp6/Epiprofin is a master regulator in the developing tooth Rhodes, CS; Yoshitomi, Y; Burbelo, PD et al. Biochem Biophys Res Commun, DOI://10.1016/j.bbrc.2021.10.017 (2021)
Deep Learning CT-based Quantitative Visualization Tool for Liver Volume Estimation: Defining Normal and Hepatomegaly Perez, AA; Noe-Kim, V; Lubner, MG et al. Radiology, DOI://10.1148/radiol.2021210531 (2021)
Genomic and evolutionary classification of lung cancer in never smokers Zhang, T; Joubert, P; Ansari-Pour, N et al. Nat Genet, DOI://10.1038/s41588-021-00920-0 (2021)
Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing Fang, LT; Zhu, B; Zhao, Y et al. Nat Biotechnol, DOI://10.1038/s41587-021-00993-6 (2021)

Rigorous treatment of pairwise and many-body electrostatic interactions among dielectric spheres at the Debye-Hückel level Obolensky, OI; Doerr, TP; Yu, YK; , Eur Phys J E Soft Matter, DOI://10.1140/epje/s10189-021-00131-9 (2021)
Ecdysoneless protein regulates viral and cellular mRNA splicing to promote cervical oncogenesis Mirza, S; Kalluchi, A; Raza, M et al. Mol Cancer Res, DOI://10.1158/1541-7786.MCR-21-0567 (2021)
A novel exome probe set captures phototransduction genes across birds (Aves) enabling efficient analysis of vision evolution White, ND; Batz, ZA; Braun, EL et al. Mol Ecol Resour, DOI://10.1111/1755-0998.13496 (2021)
Adintoviruses: a proposed animal-tropic family of midsize eukaryotic linear dsDNA (MELD) viruses Starrett, GJ; Tisza, MJ; Welch, NL et al. Virus Evol, DOI://10.1093/ve/veaa055 (2021)
A mixed-model approach for powerful testing of genetic associations with cancer risk incorporating tumor characteristics Zhang, H; Zhao, N; Ahearn, TU et al. Biostatistics, DOI://10.1093/biostatistics/kxz065 (2021)
Neanderthal-derived genetic variation in living humans relates to schizophrenia diagnosis, to psychotic symptom severity, and to dopamine synthesis Gregory, MD; Eisenberg, DP; Hamborg, M et al. Am J Med Genet B Neuropsychiatr Genet, DOI://10.1002/ajmg.b.32872 (2021)

Social groups constrain the spatiotemporal dynamics of wild sifaka gut microbiomes Perofsky, AC; Ancel Meyers, L; Abondano, LA et al. Mol Ecol, DOI://10.1111/mec.16193 (2021)
Corrections in the CHARMM36 Parametrization of Chloride Interactions with Proteins, Lipids, and Alkali Cations, and Extension to Other Halide Anions Orabi, EA; Öztürk, TN; Bernhardt, N; Faraldo-Gómez, JD; , J Chem Theory Comput, DOI://10.1021/acs.jctc.1c00550 (2021)
NMDARs Drive the Expression of Neuropsychiatric Disorder Risk Genes Within GABAergic Interneuron Subtypes in the Juvenile Brain Mahadevan, V; Mitra, A; Zhang, Y et al. Front Mol Neurosci, DOI://10.3389/fnmol.2021.712609 (2021)
Identification of DNA Methylation Changes That Predict Onset of Post-traumatic Stress Disorder and Depression Following Physical Trauma Martin, CA; Vorn, R; Schrieber, M et al. Front Neurosci, DOI://10.3389/fnins.2021.738347 (2021)
Deconstructing the Treatment Effect of Remdesivir in the Adaptive COVID-19 Treatment Trial-1: Implications for Critical Care Resource Utilization Fintzi, J; Bonnett, T; Sweeney, DA et al. Clin Infect Dis, DOI://10.1093/cid/ciab712 (2021)
Microbial signatures in the lower airways of mechanically ventilated COVID-19 patients associated with poor clinical outcome Sulaiman, I; Chung, M; Angel, L et al. Nat Microbiol, DOI://10.1038/s41564-021-00961-5 (2021)

Dual Inhibition of Histone Deacetylases and the Mechanistic Target of Rapamycin Promotes Apoptosis in Cell Line Models of Uveal Melanoma Patel, RP; Thomas, JR; Curt, KM et al. Invest Ophthalmol Vis Sci, DOI://10.1167/iovs.62.12.16 (2021)
The ETS transcription factor ERF controls the exit from the naïve pluripotent state in a MAPK-dependent manner Vega-Sendino, M; Olbrich, T; Tillo, D et al. Sci Adv, DOI://10.1126/sciadv.abg8306 (2021)
Blockade of GRTH/DDX25 Phosphorylation by Cyclic Peptides Provides an Avenue for Developing a Nonhormonal Male Contraceptive Raju, M; Kavarthapu, R; Anbazhagan, R et al. J Med Chem, DOI://10.1021/acs.jmedchem.1c01201 (2021)
Long term follow-up of a phase II study of cladribine with concurrent rituximab with hairy cell leukemia variant Chihara, D; Arons, E; Stetler-Stevenson, M et al. Blood Adv, DOI://10.1182/bloodadvances.2021005039 (2021)
Proteogenomic Analysis Unveils the HLA Class I-Presented Immunopeptidome in Melanoma and EGFR-Mutant Lung Adenocarcinoma Qi, YA; Maity, TK; Cultraro, CM et al. Mol Cell Proteomics, DOI://10.1016/j.mcpro.2021.100136 (2021)
Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action Eren, E; Watts, NR; Sackett, DL; Wingfield, PT; , J Biol Chem, DOI://10.1016/j.jbc.2021.101138 (2021)

Systematic investigation of cytokine signaling activity at the tissue and single-cell levels Jiang, P; Zhang, Y; Ru, B et al. Nat Methods, DOI://10.1038/s41592-021-01274-5 (2021)
The taxonomic distribution of histamine-secreting bacteria in the human gut microbiome Mou, Z; Yang, Y; Hall, AB; Jiang, X; , BMC Genomics, DOI://10.1186/s12864-021-08004-3 (2021)
A lymphocyte-microglia-astrocyte axis in chronic active multiple sclerosis Absinta, M; Maric, D; Gharagozloo, M et al. Nature, DOI://10.1038/s41586-021-03892-7 (2021)
Binding of regulatory proteins to nucleosomes is modulated by dynamic histone tails Peng, Y; Li, S; Onufriev, A et al. Nat Commun, DOI://10.1038/s41467-021-25568-6 (2021)
Joint testing of overall and simple effects for the two-by-two factorial trial design Leifer, ES; Troendle, JF; Kolecki, A; Follmann, DA; , Clin Trials, DOI://10.1177/17407745211014493 (2021)
Impact of depression and stress on placental DNA methylation in ethnically diverse pregnant women Tesfaye, M; Chatterjee, S; Zeng, X et al. Epigenomics, DOI://10.2217/epi-2021-0192 (2021)

Altered regulation of DPF3, a member of the SWI/SNF complexes, underlies the 14q24 renal cancer susceptibility locus Colli, LM; Jessop, L; Myers, TA et al. Am J Hum Genet, DOI://10.1016/j.ajhg.2021.07.009 (2021)
NOTCH-mediated ex vivo expansion of human hematopoietic stem and progenitor cells by culture under hypoxia Araki, D; Fu, JF; Huntsman, H et al. Stem Cell Reports, DOI://10.1016/j.stemcr.2021.08.001 (2021)
Specific β-Defensins Stimulate Pruritus through Activation of Sensory Neurons Tseng, PY; Hoon, MA; , J Invest Dermatol, DOI://10.1016/j.jid.2021.07.178 (2021)
Transcriptomic profiling in canines and humans reveals cancer specific gene modules and biological mechanisms common to both species Tawa, GJ; Braisted, J; Gerhold, D et al. PLoS Comput Biol, DOI://10.1371/journal.pcbi.1009450 (2021)
Genome-Wide Analysis Unveils DNA Helicase RECQ1 as a Regulator of Estrogen Response Pathway in Breast Cancer Cells Lu, X; Redon, CE; Tang, W et al. Mol Cell Biol, DOI://10.1128/MCB.00515-20 (2021)
Training Spiking Neural Networks in the Strong Coupling Regime Kim, CM; Chow, CC; , Neural Comput, DOI://10.1162/neco_a_01379 (2021)
Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium Shern, JF; Selfe, J; Izquierdo, E et al. J Clin Oncol, DOI://10.1200/JCO.20.03060 (2021)
An engineered IL-2 partial agonist promotes CD8 + T cell stemness Mo, F; Yu, Z; Li, P et al. Nature, DOI://10.1038/s41586-021-03861-0 (2021)
Progesterone promotes immunomodulation and tumor development in the murine mammary gland Werner, LR; Gibson, KA; Goodman, ML et al. J Immunother Cancer, DOI://10.1136/jitc-2020-001710 (2021)
Stem-like cells drive NF1-associated MPNST functional heterogeneity and tumor progression Sun, D; Xie, XP; Zhang, X et al. Cell Stem Cell, DOI://10.1016/j.stem.2021.04.029 (2021)
Tumor metabolism and associated serum metabolites define prognostic subtypes of Asian hepatocellular carcinoma Pomyen, Y; Budhu, A; Chaisaingmongkol, J et al. Sci Rep, DOI://10.1038/s41598-021-91560-1 (2021)
Identification of bacteria-derived HLA-bound peptides in melanoma Kalaora, S; Nagler, A; Nejman, D et al. Nature, DOI://10.1038/s41586-021-03368-8 (2021)
CBFB cooperates with p53 to maintain TAp73 expression and suppress breast cancer Malik, N; Yan, H; Yang, HH et al. PLoS Genet, DOI://10.1371/journal.pgen.1009553 (2021)
Fully-Automated Deep Learning Tool for Sarcopenia Assessment on CT: L1 Versus L3 Vertebral Level Muscle Measurements for Opportunistic Prediction of Adverse Clinical Outcomes Pickhardt, PJ; Perez, AA; Garrett, JW et al. AJR Am J Roentgenol, DOI://10.2214/AJR.21.26486 (2021)
Identification and Validation of T-cell Receptors Targeting RAS Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy Levin, N; Paria, BC; Vale, NR et al. Clin Cancer Res, DOI://10.1158/1078-0432.CCR-21-0849 (2021)
Chromosome 8 gain is associated with high-grade transformation in MPNST Dehner, C; Moon, CI; Zhang, X et al. JCI Insight, DOI://10.1172/jci.insight.146351 (2021)
Identifying and characterizing virus-encoded circular RNAs Tagawa, T; Kopardé, VN; Ziegelbauer, JM; , Methods, DOI://10.1016/j.ymeth.2021.03.004 (2021)
Two mechanisms of chromosome fragility at replication-termination sites in bacteria Mei, Q; Fitzgerald, DM; Liu, J et al. Sci Adv, DOI://10.1126/sciadv.abe2846 (2021)

Dual PD-L1 and TGF-b blockade in patients with recurrent respiratory papillomatosis Robbins, Y; Friedman, J; Clavijo, PE et al. J Immunother Cancer, DOI://10.1136/jitc-2021-003113 (2021)
Treatment of Relapsing HPV Diseases by Restored Function of Natural Killer Cells Lisco, A; Hsu, AP; Dimitrova, D et al. N Engl J Med, DOI://10.1056/NEJMoa2102715 (2021)
Biomedical Vocabulary Alignment at Scale in the UMLS Metathesaurus Nguyen, V; Yip, HY; Bodenreider, O; , Proc Int World Wide Web Conf, DOI://10.1145/3442381.3450128 (2021)
The third-generation EGFR inhibitor almonertinib (HS-10296) resensitizes ABCB1-overexpressing multidrug-resistant cancer cells to chemotherapeutic drugs Wu, CP; Hung, TH; Lusvarghi, S et al. Biochem Pharmacol, DOI://10.1016/j.bcp.2021.114516 (2021)
Compromised counterselection by FAS creates an aggressive subtype of germinal center lymphoma Razzaghi, R; Agarwal, S; Kotlov, N et al. J Exp Med, DOI://10.1084/jem.20201173 (2021)
Gut microbiota development during infancy: Impact of introducing allergenic foods Marrs, T; Jo, JH; Perkin, MR et al. J Allergy Clin Immunol, DOI://10.1016/j.jaci.2020.09.042 (2021)

Immune cell deconvolution of bulk DNA methylation data reveals an association with methylation class, key somatic alterations, and cell state in glial/glioneuronal tumors Singh, O; Pratt, D; Aldape, K; , Acta Neuropathol Commun, DOI://10.1186/s40478-021-01249-9 (2021)
Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing Xiao, W; Ren, L; Chen, Z et al. Nat Biotechnol, DOI://10.1038/s41587-021-00994-5 (2021)
Skin Metagenomic Sequence Analysis of Early Candida auris Outbreaks in U.S. Nursing Homes Huang, X; Welsh, RM; Deming, C et al. mSphere, DOI://10.1128/mSphere.00287-21 (2021)
Toward Reducing hERG Affinities for DAT Inhibitors with a Combined Machine Learning and Molecular Modeling Approach Lee, KH; Fant, AD; Guo, J et al. J Chem Inf Model, DOI://10.1021/acs.jcim.1c00856 (2021)
Identification of human long noncoding RNAs associated with nonalcoholic fatty liver disease and metabolic homeostasis Ruan, X; Li, P; Ma, Y et al. J Clin Invest, DOI://10.1172/JCI136336 (2021)
Magnetization transfer weighted EPI facilitates cortical depth determination in native fMRI space Chai, Y; Li, L; Wang, Y et al. Neuroimage, DOI://10.1016/j.neuroimage.2021.118455 (2021)
ZFTA Translocations Constitute Ependymoma Chromatin Remodeling and Transcription Factors Kupp, R; Ruff, L; Terranova, S et al. Cancer Discov, DOI://10.1158/2159-8290.CD-20-1052 (2021)
Understanding tumour cell heterogeneity and its implication for immunotherapy in liver cancer using single-cell analysis Heinrich, S; Craig, AJ; Ma, L et al. J Hepatol, DOI://10.1016/j.jhep.2020.11.036 (2021)
A penalized regression framework for building polygenic risk models based on summary statistics from genome-wide association studies and incorporating external information Chen, TH; Chatterjee, N; Landi, MT; Shi, J; , J Am Stat Assoc, DOI://10.1080/01621459.2020.1764849 (2021)
Differences in risk factors for molecular subtypes of clear cell renal cell carcinoma Purdue, MP; Rhee, J; Moore, L et al. Int J Cancer, DOI://10.1002/ijc.33701 (2021)
A Novel ARL3 Gene Mutation Associated With Autosomal Dominant Retinal Degeneration Ratnapriya, R; Jacobson, SG; Cideciyan, AV et al. Front Cell Dev Biol, DOI://10.3389/fcell.2021.720782 (2021)
Determinants of conductance of a bacterial voltage-gated sodium channel Chen, AY; Brooks, BR; Damjanovic, A; , Biophys J, DOI://10.1016/j.bpj.2021.06.013 (2021)

Genetic risk scores for cardiometabolic traits in sub-Saharan African populations Ekoru, K; Adeyemo, AA; Chen, G et al. Int J Epidemiol, DOI://10.1093/ije/dyab046 (2021)
Cell-free DNA ultra-low-pass whole genome sequencing to distinguish malignant peripheral nerve sheath tumor (MPNST) from its benign precursor lesion: A cross-sectional study Szymanski, JJ; Sundby, RT; Jones, PA et al. PLoS Med, DOI://10.1371/journal.pmed.1003734 (2021)
SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity Olia, AS; Tsybovsky, Y; Chen, SJ et al. J Biol Chem, DOI://10.1016/j.jbc.2021.101127 (2021)
Prenatal maternal infection promotes tissue-specific immunity and inflammation in offspring Lim, AI; McFadden, T; Link, VM et al. Science, DOI://10.1126/science.abf3002 (2021)
X-chromosome influences on neuroanatomical variation in humans Mallard, TT; Liu, S; Seidlitz, J et al. Nat Neurosci, DOI://10.1038/s41593-021-00890-w (2021)
Topographical and laminar distribution of audiovisual processing within human planum temporale Chai, Y; Liu, TT; Marrett, S et al. Prog Neurobiol, DOI://10.1016/j.pneurobio.2021.102121 (2021)

Origin of the Isomer Stability of Polymethylated DOTA Chelates Complexed with Ln3+ Ions Yong-Sok Lee, Zhongyou Mou et al Eur. J. Inorg. Chem, doi://10.1002/ejic.202100252 (2021)
Empirical Findings on the Role of Structured Data, Unstructured Data, and their Combination for Automatic Clinical Phenotyping Moldwin, A; Demner-Fushman, D; Goodwin, TR; , AMIA Annu Symp Proc, 1942-597X (2021)
The trans-ancestral genomic architecture of glycemic traits Chen, J; Spracklen, CN; Marenne, G et al. Nat Genet, DOI://10.1038/s41588-021-00852-9 (2021)
Compound heterozygous KCTD7 variants in progressive myoclonus epilepsy Burke, EA; Sturgeon, M; Zastrow, DB et al. J Neurogenet, DOI://10.1080/01677063.2021.1892095 (2021)
Genetic contributions to alcohol use disorder treatment outcomes: a genome-wide pharmacogenomics study Biernacka, JM; Coombes, BJ; Batzler, A et al. Neuropsychopharmacology, DOI://10.1038/s41386-021-01097-0 (2021)
The N terminus of α-synuclein dictates fibril formation McGlinchey, RP; Ni, X; Shadish, JA et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2023487118 (2021)

Hedgehog dysregulation contributes to tissue-specific inflammaging of resident macrophages Babagana, M; Oh, KS; Chakraborty, S et al. Aging (Albany NY), DOI://10.18632/aging.203422 (2021)
Recovering prokaryotic genomes from host-associated, short-read shotgun metagenomic sequencing data Saheb Kashaf, S; Almeida, A; Segre, JA; Finn, RD; , Nat Protoc, DOI://10.1038/s41596-021-00508-2 (2021)
Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging McCartney, DL; Min, JL; Richmond, RC et al. Genome Biol, DOI://10.1186/s13059-021-02398-9 (2021)
Effects of processed meat and drinking water nitrate on oral and fecal microbial populations in a controlled feeding study Sinha, R; Zhao, N; Goedert, JJ et al. Environ Res, DOI://10.1016/j.envres.2021.111084 (2021)
Dynamic Time Warping Identifies Functionally Distinct fMRI Resting State Cortical Networks Specific to VTA and SNc: A Proof of Concept Philips, RT; Torrisi, SJ; Gorka, AX et al. Cereb Cortex, DOI://10.1093/cercor/bhab273 (2021)
Rat PRDM9 shapes recombination landscapes, duration of meiosis, gametogenesis, and age of fertility Mihola, O; Landa, V; Pratto, F et al. BMC Biol, DOI://10.1186/s12915-021-01017-0 (2021)
Amygdala Functional Connectivity and Negative Reactive Temperament at Age 4 Months Filippi, CA; Ravi, S; Bracy, M et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2020.11.021 (2021)
Sperm acrosome overgrowth and infertility in mice lacking chromosome 18 pachytene piRNA Choi, H; Wang, Z; Dean, J; , PLoS Genet, DOI://10.1371/journal.pgen.1009485 (2021)
Intratumoral γδ T-Cell Infiltrates, Chemokine (C-C Motif) Ligand 4/Chemokine (C-C Motif) Ligand 5 Protein Expression and Survival in Patients With Hepatocellular Carcinoma Zhao, N; Dang, H; Ma, L et al. Hepatology, DOI://10.1002/hep.31412 (2021)
FOXF1 is required for the oncogenic properties of PAX3-FOXO1 in rhabdomyosarcoma Milewski, D; Shukla, S; Gryder, BE et al. Oncogene, DOI://10.1038/s41388-021-01694-9 (2021)
Single-cell atlas of tumor cell evolution in response to therapy in hepatocellular carcinoma and intrahepatic cholangiocarcinoma Ma, L; Wang, L; Khatib, SA et al. J Hepatol, DOI://10.1016/j.jhep.2021.06.028 (2021)
High-resolution structure and strain comparison of infectious mammalian prions Kraus, A; Hoyt, F; Schwartz, CL et al. Mol Cell, DOI://10.1016/j.molcel.2021.08.011 (2021)

Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants Xu, J; Xu, K; Jung, S et al. Nature, DOI://10.1038/s41586-021-03676-z (2021)
Novel Tsg101 Binding Partners Regulate Viral L Domain Trafficking Strickland, M; Nyenhuis, D; Watanabe, SM et al. Viruses, DOI://10.3390/v13061147 (2021)
An Integrative Genomic Strategy Identifies sRAGE as a Causal and Protective Biomarker of Lung Function Keefe, J; Yao, C; Hwang, SJ et al. Chest, DOI://10.1016/j.chest.2021.06.053 (2021)
Bias correction for estimates from linear excess relative risk models in small case-control studies Roberti, S; van Leeuwen, FE; Hauptmann, M; Pfeiffer, RM; , Stat Med, DOI://10.1002/sim.9158 (2021)
Regional White Matter Scaling in the Human Brain Warling, A; McDermott, CL; Liu, S et al. J Neurosci, DOI://10.1523/JNEUROSCI.1193-21.2021 (2021)
Experimental Babesia rossi infection induces hemolytic, metabolic, and viral response pathways in the canine host Smith, RL; Goddard, A; Boddapati, A et al. BMC Genomics, DOI://10.1186/s12864-021-07889-4 (2021)

Granzyme A and CD160 expression delineates ILC1 with graded functions in the mouse liver Di Censo, C; Marotel, M; Mattiola, I et al. Eur J Immunol, DOI://10.1002/eji.202149209 (2021)
Mechanistic basis of breast cancer resistance protein inhibition by new indeno[1,2-b]indoles Kita, DH; Guragossian, N; Zattoni, IF et al. Sci Rep, DOI://10.1038/s41598-020-79892-w (2021)
POLD1 Deficiency Reveals a Role for POLD1 in DNA Repair and T and B Cell Development Nichols-Vinueza, DX; Delmonte, OM; Bundy, V et al. J Clin Immunol, DOI://10.1007/s10875-020-00903-6 (2021)
Genome-wide covariation in SARS-CoV-2 Cresswell-Clay, E; Periwal, V; , Math Biosci, DOI://10.1016/j.mbs.2021.108678 (2021)
Atomic view of cosolute-induced protein denaturation probed by NMR solvent paramagnetic relaxation enhancement Okuno, Y; Yoo, J; Schwieters, CD et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2112021118 (2021)
Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding Han, S; Okawa, S; Wilkinson, GA et al. Neuron, DOI://10.1016/j.neuron.2021.07.007 (2021)
Fecal microbiota transplant overcomes resistance to anti-PD-1 therapy in melanoma patients Davar, D; Dzutsev, AK; McCulloch, JA et al. Science, DOI://10.1126/science.abf3363 (2021)
Sclerosing Sialadenitis Is Associated With Salivary Gland Hypofunction and a Unique Gene Expression Profile in Sjögren's Syndrome Yin H, Pranzatelli TJF et al. Front Immunol ., doi://10.3389/fimmu.2021.699722. (2021)
The large bat Helitron DNA transposase forms a compact monomeric assembly that buries and protects its covalently bound 5'-transposon end Kosek, D; Grabundzija, I; Lei, H et al. Mol Cell, DOI://10.1016/j.molcel.2021.07.028 (2021)
Identification of Accessible Hepatic Gene Signatures for Interindividual Variations in Nutrigenomic Response to Dietary Supplementation of Omega-3 Fatty Acids Shi, Y; Li, P; Jiang, CF et al. Cells, DOI://10.3390/cells10020467 (2021)
Mouse papillomavirus type 1 (MmuPV1) DNA is frequently integrated in benign tumors by microhomology-mediated end-joining Yu, L; Majerciak, V; Xue, XY et al. PLoS Pathog, DOI://10.1371/journal.ppat.1009812 (2021)
RGC-32 Acts as a Hub to Regulate the Transcriptomic Changes Associated With Astrocyte Development and Reactive Astrocytosis Tatomir, A; Beltrand, A; Nguyen, V et al. Front Immunol, DOI://10.3389/fimmu.2021.705308 (2021)
Identification of retinal ganglion cell types and brain nuclei expressing the transcription factor Brn3c/Pou4f3 using a Cre recombinase knock-in allele Parmhans, N; Fuller, AD; Nguyen, E et al. J Comp Neurol, DOI://10.1002/cne.25065 (2021)
Hepcidin-regulating iron metabolism genes and pancreatic ductal adenocarcinoma: a pathway analysis of genome-wide association studies Julián-Serrano, S; Yuan, F; Wheeler, W et al. Am J Clin Nutr, DOI://10.1093/ajcn/nqab217 (2021)
JAK inhibitors dampen activation of interferon-activated transcriptomes and the SARS-CoV-2 receptor ACE2 in human renal proximal tubules Jankowski, J; Lee, HK; Wilflingseder, J; Hennighausen, L; , iScience, DOI://10.1016/j.isci.2021.102928 (2021)
Color Space Geometry Uncovered with Magnetoencephalography Rosenthal, IA; Singh, SR; Hermann, KL et al. Curr Biol, DOI://10.1016/j.cub.2021.02.023 (2021)
The X-linked acrogigantism-associated gene gpr101 is a regulator of early embryonic development and growth in zebrafish Trivellin, G; Tirosh, A; Hernández-Ramírez, LC et al. Mol Cell Endocrinol, DOI://10.1016/j.mce.2020.111091 (2021)
How to Interpret Resting-State fMRI: Ask Your Participants Gonzalez-Castillo, J; Kam, JWY; Hoy, CW; Bandettini, PA; , J Neurosci, DOI://10.1523/JNEUROSCI.1786-20.2020 (2021)

RepairSig: Deconvolution of DNA damage and repair contributions to the mutational landscape of cancer Wojtowicz, D; Hoinka, J; Amgalan, B et al. Cell Syst, DOI://10.1016/j.cels.2021.07.004 (2021)
Contrasting Patterns of Gene Duplication, Relocation, and Selection Among Human Taste Genes Wang, Y; Sun, Y; Joseph, PV; , Evol Bioinform Online, DOI://10.1177/11769343211035141 (2021)
Translational autoregulation of the S. cerevisiae high-affinity polyamine transporter Hol1 Vindu, A; Shin, BS; Choi, K et al. Mol Cell, DOI://10.1016/j.molcel.2021.07.020 (2021)
A phage-encoded nucleoid associated protein compacts both host and phage DNA and derepresses H-NS silencing Son, B; Patterson-West, J; Arroyo-Mendoza, M et al. Nucleic Acids Res, DOI://10.1093/nar/gkab678 (2021)
Branebrutinib (BMS-986195), a Bruton's Tyrosine Kinase Inhibitor, Resensitizes P-Glycoprotein-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Agents Wu, CP; Murakami, M; Wu, YS et al. Front Cell Dev Biol, DOI://10.3389/fcell.2021.699571 (2021)
Distinct Mitochondrial Pathologies Caused by Mutations of the Proximal Tubular Enzymes EHHADH and GATM Forst, AL; Reichold, M; Kleta, R; Warth, R; , Front Physiol, DOI://10.3389/fphys.2021.715485 (2021)

Use of Variational Autoencoders with Unsupervised Learning to Detect Incorrect Organ Segmentations at CT Sandfort, V; Yan, K; Graffy, PM et al. Radiol Artif Intell, DOI://10.1148/ryai.2021200218 (2021)
gEAR: Gene Expression Analysis Resource portal for community-driven, multi-omic data exploration Orvis, J; Gottfried, B; Kancherla, J et al. Nat Methods, DOI://10.1038/s41592-021-01200-9 (2021)
Serine hydroxymethyltransferase 2 expression promotes tumorigenesis in rhabdomyosarcoma with 12q13-q14 amplification Nguyen, TH; Vemu, PL; Hoy, GE et al. J Clin Invest, DOI://10.1172/JCI138022 (2021)
Aberrant type 1 immunity drives susceptibility to mucosal fungal infections Break, TJ; Oikonomou, V; Dutzan, N et al. Science, DOI://10.1126/science.aay5731 (2021)
The p53-induced RNA-binding protein ZMAT3 is a splicing regulator that inhibits the splicing of oncogenic CD44 variants in colorectal carcinoma Muys, BR; Anastasakis, DG; Claypool, D et al. Genes Dev, DOI://10.1101/gad.342634.120 (2021)
Host-Virus Chimeric Events in SARS-CoV-2-Infected Cells Are Infrequent and Artifactual Yan, B; Chakravorty, S; Mirabelli, C et al. J Virol, DOI://10.1128/JVI.00294-21 (2021)

Direct identification of neoantigen-specific TCRs from tumor specimens by high-throughput single-cell sequencing Lu, YC; Zheng, Z; Lowery, FJ et al. J Immunother Cancer, DOI://10.1136/jitc-2021-002595 (2021)
Resting-State Functional Connectivity and Psychopathology in Klinefelter Syndrome (47, XXY) Whitman, ET; Liu, S; Torres, E et al. Cereb Cortex, DOI://10.1093/cercor/bhab077 (2021)
A computational network perspective on pediatric anxiety symptoms Abend, R; Bajaj, MA; Coppersmith, DDL et al. Psychol Med, DOI://10.1017/S0033291720000501 (2021)
Strengths and challenges of longitudinal non-human primate neuroimaging Song, X; García-Saldivar, P; Kindred, N et al. Neuroimage, DOI://10.1016/j.neuroimage.2021.118009 (2021)
Shifts in the Skin Bacterial and Fungal Communities of Healthy Children Transitioning through Puberty Park, J; Schwardt, NH; Jo, JH et al. J Invest Dermatol, DOI://10.1016/j.jid.2021.04.034 (2021)
Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA Ma, R; Lian, T; Huang, R et al. Nat Microbiol, DOI://10.1038/s41564-020-00858-9 (2021)

Unusual phenotypes in patients with a pathogenic germline variant in DICER1 Venger, K; Elbracht, M; Carlens, J et al. Fam Cancer, DOI://10.1007/s10689-021-00271-z (2021)
Clinical Manifestations, Mutational Analysis, and Immunological Phenotype in Patients with RAG1/2 Mutations: First Cases Series from Mexico and Description of Two Novel Mutations Lugo-Reyes, SO; Pastor, N; González-Serrano, E et al. J Clin Immunol, DOI://10.1007/s10875-021-01052-0 (2021)
Distinguishing type II focal cortical dysplasias from normal cortex: A novel normative modeling approach Snyder, K; Whitehead, EP; Theodore, WH et al. Neuroimage Clin, DOI://10.1016/j.nicl.2021.102565 (2021)
The genome of the stable fly, Stomoxys calcitrans, reveals potential mechanisms underlying reproduction, host interactions, and novel targets for pest control Olafson, PU; Aksoy, S; Attardo, GM et al. BMC Biol, DOI://10.1186/s12915-021-00975-9 (2021)
Toward a Liver Cell Atlas: Understanding Liver Biology in Health and Disease at Single-Cell Resolution Ma, L; Khatib, S; Craig, AJ; Wang, XW; , Semin Liver Dis, DOI://10.1055/s-0041-1729970 (2021)
Mutant Idh2 cooperates with a NUP98-HOXD13 fusion to induce early immature thymocyte precursor ALL Goldberg, L; Negi, V; Chung, YJ et al. Cancer Res, DOI://10.1158/0008-5472.CAN-21-1027 (2021)
Gene-Based Association Testing of Dichotomous Traits With Generalized Functional Linear Mixed Models Using Extended Pedigrees: Applications to Age-Related Macular Degeneration Jiang, Y; Chiu, CY; Yan, Q et al. J Am Stat Assoc, DOI://10.1080/01621459.2020.1799809 (2021)
Acute ambient air pollution exposure and placental Doppler results in the NICHD fetal growth studies - Singleton cohort Ouidir, M; Tekola-Ayele, F; Canty, T et al. Environ Res, DOI://10.1016/j.envres.2021.111728 (2021)
Monocyte Subsets With High Osteoclastogenic Potential and Their Epigenetic Regulation Orchestrated by IRF8 Das, A; Wang, X; Kang, J et al. J Bone Miner Res, DOI://10.1002/jbmr.4165 (2021)
Emotional distractors and attentional control in anxious youth: eye tracking and fMRI data Smith, AR; Haller, SP; Haas, SA et al. Cogn Emot, DOI://10.1080/02699931.2020.1816911 (2021)
Endogenous retroviruses drive lineage-specific regulatory evolution across primate and rodent placentae Sun, MA; Wolf, G; Wang, Y et al. Mol Biol Evol, DOI://10.1093/molbev/msab223 (2021)
Frequency of Pathogenic Germline Variants in Cancer-Susceptibility Genes in the Childhood Cancer Survivor Study Kim, J; Gianferante, M; Karyadi, DM et al. JNCI Cancer Spectr, DOI://10.1093/jncics/pkab007 (2021)

In vivo evolution of an emerging zoonotic bacterial pathogen in an immunocompromised human host Launay, A; Wu, CJ; Dulanto Chiang, A et al. Nat Commun, DOI://10.1038/s41467-021-24668-7 (2021)
A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids Jhun, MA; Mendelson, M; Wilson, R et al. Nat Commun, DOI://10.1038/s41467-021-23899-y (2021)
PD-1 blockade exacerbates Mycobacterium tuberculosis infection in rhesus macaques Kauffman, KD; Sakai, S; Lora, NE et al. Sci Immunol, DOI://10.1126/sciimmunol.abf3861 (2021)
M1BP cooperates with CP190 to activate transcription at TAD borders and promote chromatin insulator activity Bag, I; Chen, S; Rosin, LF et al. Nat Commun, DOI://10.1038/s41467-021-24407-y (2021)
Oncogenic Hedgehog-smoothened signaling depends on YAP1-TAZ/TEAD transcription to restrain differentiation in basal cell carcinoma Yuan, Y; Salinas Parra, N; Chen, Q; Iglesias-Bartolome, R; , J Invest Dermatol, DOI://10.1016/j.jid.2021.06.020 (2021)
Targeting a noncanonical, hairpin-containing G-quadruplex structure from the MYCN gene Yang, M; Carter, S; Parmar, S et al. Nucleic Acids Res, DOI://10.1093/nar/gkab594 (2021)
Budding epithelial morphogenesis driven by cell-matrix versus cell-cell adhesion Wang, S; Matsumoto, K; Lish, SR et al. Cell, DOI://10.1016/j.cell.2021.05.015 (2021)
Modelling PNPLA3-Associated Non-Alcoholic Fatty Liver Disease Using Human Induced Pluripotent Stem Cells Tilson, SG; Morell, CM; Lenaerts, AS et al. Hepatology, DOI://10.1002/hep.32063 (2021)
Statistical learning occurs during practice while high-order rule learning during rest period Quentin, R; Fanuel, L; Kiss, M et al. NPJ Sci Learn, DOI://10.1038/s41539-021-00093-9 (2021)
A Randomized Controlled Trial of Computerized Interpretation Bias Training for Disruptive Mood Dysregulation Disorder: A Fast-Fail Study Haller, SP; Stoddard, J; Botz-Zapp, C et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2021.05.022 (2021)
Characterizing Expression and Regulation of Gamma-Herpesviral Circular RNAs Tagawa, T; Oh, D; Santos, J et al. Front Microbiol, DOI://10.3389/fmicb.2021.670542 (2021)
The dystonia gene THAP1 controls DNA double-strand break repair choice Shinoda, K; Zong, D; Callen, E et al. Mol Cell, DOI://10.1016/j.molcel.2021.03.034 (2021)

PARK7-Related Early Onset Parkinson Disease in the Setting of Complete Uniparental Isodisomy of Chromosome 1 Xiao, C; Markello, T; Zein, WM et al. Neurol Genet, DOI://10.1212/NXG.0000000000000606 (2021)
Genetic and evolutionary analysis of SARS-CoV-2 circulating in the region surrounding Islamabad, Pakistan Tamim, S; Trovao, NS; Thielen, P et al. Infect Genet Evol, DOI://10.1016/j.meegid.2021.105003 (2021)
Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry Graff, M; Justice, AE; Young, KL et al. Am J Hum Genet, DOI://10.1016/j.ajhg.2021.02.011 (2021)
A fluorescence-based genetic screen reveals diverse mechanisms silencing small RNA signaling in E. coli Chen, J; To, L; de Mets, F et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2106964118 (2021)
Computational Modeling of C-Terminal Tails to Predict the Calcium-Dependent Secretion of Endoplasmic Reticulum Resident Proteins Trychta, KA; Xie, B; Verma, RK et al. Front Chem, DOI://10.3389/fchem.2021.689608 (2021)
Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease Tumburu, L; Ghosh-Choudhary, S; Seifuddin, FT et al. Blood, DOI://10.1182/blood.2020009063 (2021)
Multimodal Molecular Imaging Detects Early Responses to Immune Checkpoint Blockade Saida, Y; Brender, JR; Yamamoto, K et al. Cancer Res, DOI://10.1158/0008-5472.CAN-20-3182 (2021)
Landscape of GPCR expression along the mouse nephron Poll, BG; Chen, L; Chou, CL et al. Am J Physiol Renal Physiol, DOI://10.1152/ajprenal.00077.2021 (2021)
Fine-tuning neural excitation/inhibition for tailored ketamine use in treatment-resistant depression Fagerholm, ED; Leech, R; Williams, S et al. Transl Psychiatry, DOI://10.1038/s41398-021-01442-3 (2021)
Meiotic recombination mirrors patterns of germline replication in mice and humans Pratto, F; Brick, K; Cheng, G et al. Cell, DOI://10.1016/j.cell.2021.06.025 (2021)
Prior Cocaine Use Alters the Normal Evolution of Information Coding in Striatal Ensembles during Value-Guided Decision-Making Mueller, LE; Sharpe, MJ; Stalnaker, TA et al. J Neurosci, DOI://10.1523/JNEUROSCI.1755-20.2020 (2021)
A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells Chen, Y; Tristan, CA; Chen, L et al. Nat Methods, DOI://10.1038/s41592-021-01126-2 (2021)

Host-virus chimeric events in SARS-CoV2 infected cells are infrequent and artifactual Yan, B; Chakravorty, S; Mirabelli, C et al. bioRxiv, DOI://10.1101/2021.02.17.431704 (2021)
Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer Roper, N; Velez, MJ; Chiappori, A et al. Nat Commun, DOI://10.1038/s41467-021-24164-y (2021)
The combined action of CTCF and its testis-specific paralog BORIS is essential for spermatogenesis Rivero-Hinojosa, S; Pugacheva, EM; Kang, S et al. Nat Commun, DOI://10.1038/s41467-021-24140-6 (2021)
Analysis of PTRHD1 common and rare variants in European patients with Parkinson's disease Sosero, YL; Bandres-Ciga, S; Gan-Or, Z et al. Neurobiol Aging, DOI://10.1016/j.neurobiolaging.2021.06.005 (2021)
Navigator-Guided Motion and B0 Correction of T2*-Weighted Magnetic Resonance Imaging Improves Multiple Sclerosis Cortical Lesion Detection Liu, J; Beck, ES; Filippini, S et al. Invest Radiol, DOI://10.1097/RLI.0000000000000754 (2021)
Retbindin mediates light-damage in mouse retina while its absence leads to premature retinal aging Fan, J; Rajapakse, D; Peterson, K et al. Exp Eye Res, DOI://10.1016/j.exer.2021.108698 (2021)

Personalized Single-Cell Proteogenomics to Distinguish Acute Myeloid Leukemia from Nonmalignant Clonal Hematopoiesis Dillon, LW; Ghannam, J; Nosiri, C et al. Cancer Discov, DOI://10.1158/2643-3230.BCD-21-0046 (2021)
Histone tails as signaling antennas of chromatin Peng, Y; Li, S; Landsman, D; Panchenko, AR; , Curr Opin Struct Biol, DOI://10.1016/j.sbi.2020.10.018 (2021)
A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis Disatham, J; Brennan, L; Chauss, D et al. BMC Genomics, DOI://10.1186/s12864-021-07795-9 (2021)
Consolidation of human skill linked to waking hippocampo-neocortical replay Buch, ER; Claudino, L; Quentin, R et al. Cell Rep, DOI://10.1016/j.celrep.2021.109193 (2021)
The Parkinson's Disease DNA Variant Browser Kim, JJ; Makarious, MB; Bandres-Ciga, S et al. Mov Disord, DOI://10.1002/mds.28488 (2021)
Genetic Variation and Recurrent Haplotypes on Chromosome 6q23-25 Risk Locus in Familial Lung Cancer Musolf, AM; Simpson, CL; Moiz, BA et al. Cancer Res, DOI://10.1158/0008-5472.CAN-20-3196 (2021)

LayNii: A software suite for layer-fMRI Huber, LR; Poser, BA; Bandettini, PA et al. Neuroimage, DOI://10.1016/j.neuroimage.2021.118091 (2021)
Ketamine and Attentional Bias Toward Emotional Faces: Dynamic Causal Modeling of Magnetoencephalographic Connectivity in Treatment-Resistant Depression Gilbert, JR; Galiano, CS; Nugent, AC; Zarate, CA; , Front Psychiatry, DOI://10.3389/fpsyt.2021.673159 (2021)
Dynamics of replication origin over-activation Fu, H; Redon, CE; Thakur, BL et al. Nat Commun, DOI://10.1038/s41467-021-23835-0 (2021)
Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure Wang, H; Noordam, R; Cade, BE et al. Mol Psychiatry, DOI://10.1038/s41380-021-01087-0 (2021)
CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice Li, N; Torres, MB; Spetz, MR et al. Cell Rep Med, DOI://10.1016/j.xcrm.2021.100297 (2021)
Assessing vaccine durability in randomized trials following placebo crossover Fintzi, J; Follmann, D; , Stat Med, DOI://10.1002/sim.9001 (2021)

Predictable fold switching by the SARS-CoV-2 protein ORF9b Porter, LL Protein Sci, DOI://10.1002/pro.4097 (2021)
The temporal representation of experience in subjective mood Keren, H; Zheng, C; Jangraw, DC et al. Elife, DOI://10.7554/eLife.62051 (2021)
GWAS in Africans identifies novel lipids loci and demonstrates heterogenous association within Africa Bentley, AR; Chen, G; Doumatey, AP et al. Hum Mol Genet, DOI://10.1093/hmg/ddab174 (2021)
Distinct Signatures of Genomic Copy Number Variants Define Subgroups of Merkel Cell Carcinoma Tumors Hill, NT; Kim, D; Busam, KJ et al. Cancers (Basel), DOI://10.3390/cancers13051134 (2021)
Long-term stability of avalanche scaling and integrative network organization in prefrontal and premotor cortex Miller, SR; Yu, S; Pajevic, S; Plenz, D; , Netw Neurosci, DOI://10.1162/netn_a_00188 (2021)
The mechanism of activation of monomeric B-Raf V600E Maloney, RC; Zhang, M; Jang, H; Nussinov, R; , Comput Struct Biotechnol J, DOI://10.1016/j.csbj.2021.06.007 (2021)

Functional connectivity of dorsolateral prefrontal cortex predicts cocaine relapse: implications for neuromodulation treatment Zhai, T; Salmeron, BJ; Gu, H et al. Brain Commun, DOI://10.1093/braincomms/fcab120 (2021)
Commute patterns, residential traffic-related air pollution, and lung cancer risk in the prospective UK Biobank cohort study Wong, JYY; Jones, RR; Breeze, C et al. Environ Int, DOI://10.1016/j.envint.2021.106698 (2021)
Hidden mover-stayer model for disease progression accounting for misclassified and partially observed diagnostic tests: Application to the natural history of human papillomavirus and cervical precancer Aron, J; Albert, PS; Wentzensen, N; Cheung, LC; , Stat Med, DOI://10.1002/sim.8977 (2021)
Subgenual cingulate resting regional cerebral blood flow in premenstrual dysphoric disorder: differential regulation by ovarian steroids and preliminary evidence for an association with expression of ESC/E(Z) complex genes Wei, SM; Baller, EB; Martinez, PE et al. Transl Psychiatry, DOI://10.1038/s41398-021-01328-4 (2021)
Prediction and Validation of Hematopoietic Stem and Progenitor Cell Off-Target Editing in Transplanted Rhesus Macaques AlJanahi, AA; Lazzarotto, CR; Chen, S et al. Mol Ther, DOI://10.1016/j.ymthe.2021.06.016 (2021)
Innate Immune Memory in Hematopoietic Stem/Progenitor Cells: Myeloid-Biased Differentiation and the Role of Interferon Chen, L; Ozato, K; , Front Immunol, DOI://10.3389/fimmu.2021.621333 (2021)

A catalog of tens of thousands of viruses from human metagenomes reveals hidden associations with chronic diseases Tisza, MJ; Buck, CB; , Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2023202118 (2021)
Structural insights into integrin α 5 β 1 opening by fibronectin ligand Schumacher, S; Dedden, D; Nunez, RV et al. Sci Adv, DOI://10.1126/sciadv.abe9716 (2021)
A Fusion Transcription Factor-Driven Cancer Progresses to a Fusion-Independent Relapse via Constitutive Activation of a Downstream Transcriptional Target Boudjadi, S; Pandey, PR; Chatterjee, B et al. Cancer Res, DOI://10.1158/0008-5472.CAN-20-1613 (2021)
Prospective representations in rat orbitofrontal ensembles Zhou, J; Zong, W; Jia, C et al. Behav Neurosci, DOI://10.1037/bne0000451 (2021)
Group testing can improve the cost-efficiency of prospective-retrospective biomarker studies Zhang, W; Zhang, Z; Krushkal, J; Liu, A; , BMC Med Res Methodol, DOI://10.1186/s12874-021-01239-4 (2021)
Response of human macrophages to gamma radiation is mediated via expression of endogenous retroviruses Mikhalkevich, N; O'Carroll, IP; Tkavc, R et al. PLoS Pathog, DOI://10.1371/journal.ppat.1009305 (2021)
Integrin αvβ6-TGFβ-SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer Bagati, A; Kumar, S; Jiang, P et al. Cancer Cell, DOI://10.1016/j.ccell.2020.12.001 (2021)
Functional connectivity during frustration: a preliminary study of predictive modeling of irritability in youth Scheinost, D; Dadashkarimi, J; Finn, ES et al. Neuropsychopharmacology, DOI://10.1038/s41386-020-00954-8 (2021)
Correction to: Large‑scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease Bandres-Ciga, S; Saez-Atienzar, S; Kim, JJ et al. Acta Neuropathol, DOI://10.1007/s00401-021-02309-z (2021)
Structural insights of the conserved “priming loop” of hepatitis B virus pre-genomic RNA LeBlanc, RM; Kasprzak, WK; Longhini, AP et al. J Biomol Struct Dyn, DOI://10.1080/07391102.2021.1934544 (2021)
Integrated genomic, epidemiologic investigation of Candida auris skin colonization in a skilled nursing facility Proctor, DM; Dangana, T; Sexton, DJ et al. Nat Med, DOI://10.1038/s41591-021-01383-w (2021)
Genetic and in-utero environmental contributions to DNA methylation variation in placenta Chatterjee, S; Ouidir, M; Tekola-Ayele, F; , Hum Mol Genet, DOI://10.1093/hmg/ddab161 (2021)

Functional Selectivity of a Biased Cannabinoid-1 Receptor (CB 1 R) Antagonist Liu, Z; Iyer, MR; Godlewski, G et al. ACS Pharmacol Transl Sci, DOI://10.1021/acsptsci.1c00048 (2021)
Corrigendum: Characterizing Adult Cochlear Supporting Cell Transcriptional Diversity Using Single-Cell RNA-Seq: Validation in the Adult Mouse and Translational Implications for the Adult Human Cochlea Hoa, M; Olszewski, R; Li, X et al. Front Mol Neurosci, DOI://10.3389/fnmol.2021.699859 (2021)
Investigation of Autosomal Genetic Sex Differences in Parkinson's Disease Blauwendraat, C; Iwaki, H; Makarious, MB et al. Ann Neurol, DOI://10.1002/ana.26090 (2021)
A UGT1A1 variant is associated with serum total bilirubin levels, which are causal for hypertension in African-ancestry individuals Chen, G; Adeyemo, A; Zhou, J et al. NPJ Genom Med, DOI://10.1038/s41525-021-00208-6 (2021)
Author Correction to: Endemic Burkitt lymphoma in second-degree relatives in Northern Uganda: in-depth genome-wide analysis suggests clues about genetic susceptibility Gouveia, MH; Otim, I; Ogwang, MD et al. Leukemia, DOI://10.1038/s41375-021-01140-5 (2021)
Regional Differences in Human Biliary Tissues and Corresponding In Vitro-Derived Organoids Rimland, CA; Tilson, SG; Morell, CM et al. Hepatology, DOI://10.1002/hep.31252 (2021)
Correction to: Clinical Manifestations, Mutational Analysis, and Immunological Phenotype in Patients with RAG1/2 Mutations: First Cases Series from Mexico and Description of Two Novel Mutations Lugo-Reyes, SO; Pastor, N; González-Serrano, E et al. J Clin Immunol, DOI://10.1007/s10875-021-01075-7 (2021)
Spreading and epigenetic inheritance of heterochromatin require a critical density of histone H3 lysine 9 tri-methylation Cutter DiPiazza, AR; Taneja, N; Dhakshnamoorthy, J et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2100699118 (2021)
Clinical sites of the Undiagnosed Diseases Network: unique contributions to genomic medicine and science Schoch, K; Esteves, C; Bican, A et al. Genet Med, DOI://10.1038/s41436-020-00984-z (2021)
A non-radioactive, improved PAR-CLIP and small RNA cDNA library preparation protocol Anastasakis, DG; Jacob, A; Konstantinidou, P et al. Nucleic Acids Res, DOI://10.1093/nar/gkab011 (2021)
Dynamic imaging of nascent RNA reveals general principles of transcription dynamics and stochastic splice site selection Wan, Y; Anastasakis, DG; Rodriguez, J et al. Cell, DOI://10.1016/j.cell.2021.04.012 (2021)
LRRC15 antibody-drug conjugates show promise as osteosarcoma therapeutics in preclinical studies Slemmons, KK; Mukherjee, S; Meltzer, P et al. Pediatr Blood Cancer, DOI://10.1002/pbc.28771 (2021)

JAK inhibitors dampen activation of interferon-stimulated transcription of ACE2 isoforms in human airway epithelial cells Lee, HK; Jung, O; Hennighausen, L; , Commun Biol, DOI://10.1038/s42003-021-02167-1 (2021)
Neuronal enhancers are hotspots for DNA single-strand break repair Wu, W; Hill, SE; Nathan, WJ et al. Nature, DOI://10.1038/s41586-021-03468-5 (2021)
Profiling single-cell histone modifications using indexing chromatin immunocleavage sequencing Ku, WL; Pan, L; Cao, Y et al. Genome Res, DOI://10.1101/gr.260893.120 (2021)
Human oral mucosa cell atlas reveals a stromal-neutrophil axis regulating tissue immunity Williams, DW; Greenwell-Wild, T; Brenchley, L et al. Cell, DOI://10.1016/j.cell.2021.05.013 (2021)
Innate immune cells in the tumor microenvironment Li, MO; Wolf, N; Raulet, DH et al. Cancer Cell, DOI://10.1016/j.ccell.2021.05.016 (2021)
Rare Germline Variants in Chordoma-Related Genes and Chordoma Susceptibility Yepes, S; Shah, NN; Bai, J et al. Cancers (Basel), DOI://10.3390/cancers13112704 (2021)

Biomolecular interactions of ultrasmall metallic nanoparticles and nanoclusters Sousa, AA; Schuck, P; Hassan, SA; , Nanoscale Adv, DOI://10.1039/d1na00086a (2021)
A complement factor H homolog, heparan sulfation, and syndecan maintain inversin compartment boundaries in C. elegans cilia Acker, N; Smith, H; Devine, C et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2016698118 (2021)
The mechanism of full activation of tumor suppressor PTEN at the phosphoinositide-enriched membrane Jang, H; Smith, IN; Eng, C; Nussinov, R; , iScience, DOI://10.1016/j.isci.2021.102438 (2021)
The mechanistic analysis of founder virus data in challenge models Ortega-Villa, AM; Nason, MC; Follmann, D; , Stat Med, DOI://10.1002/sim.9075 (2021)
Functional and Regulatory Roles of Fold-Switching Proteins Kim, AK; Porter, LL; , Structure, DOI://10.1016/j.str.2020.10.006 (2021)
An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids Ferdinandusse, S; McWalter, K; Te Brinke, H et al. Genet Med, DOI://10.1038/s41436-020-01027-3 (2021)

Pathogenic Germline Variants in Cancer Susceptibility Genes in Children and Young Adults With Rhabdomyosarcoma Kim, J; Light, N; Subasri, V et al. JCO Precis Oncol, DOI://10.1200/PO.20.00218 (2021)
Time-Varying Functional Connectivity Decreases as a Function of Acute Nicotine Abstinence Fedota, JR; Ross, TJ; Castillo, J et al. Biol Psychiatry Cogn Neurosci Neuroimaging, DOI://10.1016/j.bpsc.2020.10.004 (2021)
Topological polymorphism of nucleosome fibers and folding of chromatin Zhurkin, VB; Norouzi, D; , Biophys J, DOI://10.1016/j.bpj.2021.01.008 (2021)
A transcriptionally distinct subpopulation of healthy acinar cells exhibit features of pancreatic progenitors and pancreatic ductal adenocarcinoma Gopalan, V; Singh, A; Rashidi Mehrabadi, F et al. Cancer Res, DOI://10.1158/0008-5472.CAN-21-0427 (2021)
Prefrontal Responses during Proactive and Reactive Inhibition Are Differentially Impacted by Stress in Anorexia and Bulimia Nervosa Westwater, ML; Mancini, F; Gorka, AX et al. J Neurosci, DOI://10.1523/JNEUROSCI.2853-20.2021 (2021)
NLRP3 Inhibition Ameliorates Severe Cutaneous Autoimmune Manifestations in a Mouse Model of Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy-Like Disease Zhu, F; Willette-Brown, J; Zhang, J et al. J Invest Dermatol, DOI://10.1016/j.jid.2020.10.016 (2021)

AniProtDB: A Collection of Consistently Generated Metazoan Proteomes for Comparative Genomics Studies Barreira, SN; Nguyen, AD; Fredriksen, MT et al. Mol Biol Evol, DOI://10.1093/molbev/msab165 (2021)
Cutaneous T-Cell Lymphoma Skin Microbiome Is Characterized by Shifts in Certain Commensal Bacteria but not Viruses when Compared with Healthy Controls Harkins, CP; MacGibeny, MA; Thompson, K et al. J Invest Dermatol, DOI://10.1016/j.jid.2020.10.021 (2021)
Impact of Conditioning Intensity and Genomics on Relapse After Allogeneic Transplantation for Patients With Myelodysplastic Syndrome Dillon, LW; Gui, G; Logan, BR et al. JCO Precis Oncol, DOI://10.1200/PO.20.00355 (2021)
Gut microbiota composition is associated with newborn functional brain connectivity and behavioral temperament Kelsey, CM; Prescott, S; McCulloch, JA et al. Brain Behav Immun, DOI://10.1016/j.bbi.2020.11.003 (2021)
Automated picking of amyloid fibrils from cryo-EM images for helical reconstruction with RELION Thurber, KR; Yin, Y; Tycko, R; , J Struct Biol, DOI://10.1016/j.jsb.2021.107736 (2021)
Comparative Transcriptomic Analysis of the Hematopoietic System between Human and Mouse by Single Cell RNA Sequencing Gao, S; Wu, Z; Kannan, J et al. Cells, DOI://10.3390/cells10050973 (2021)
Recurrent lymphadenitis in a female XIAP/BIRC4 mutation carrier with normal lyonization Durkee-Shock, JR; Kuehn, HS; Stoddard, J et al. J Allergy Clin Immunol Pract, DOI://10.1016/j.jaip.2020.10.062 (2021)
MED1 is a lipogenesis coactivator required for postnatal adipose expansion Jang, Y; Park, YK; Lee, JE et al. Genes Dev, DOI://10.1101/gad.347583.120 (2021)
Radiation-related genomic profile of papillary thyroid carcinoma after the Chernobyl accident Morton, LM; Karyadi, DM; Stewart, C et al. Science, DOI://10.1126/science.abg2538 (2021)
A replica exchange umbrella sampling (REUS) approach to predict host-guest binding free energies in SAMPL8 challenge Ghorbani, M; Hudson, PS; Jones, MR et al. J Comput Aided Mol Des, DOI://10.1007/s10822-021-00385-7 (2021)
A Data-Driven Hydrophobicity Scale for Predicting Liquid-Liquid Phase Separation of Proteins Dannenhoffer-Lafage, T; Best, RB; , J Phys Chem B, DOI://10.1021/acs.jpcb.0c11479 (2021)
Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis Su, H; Yang, F; Fu, R et al. Cancer Cell, DOI://10.1016/j.ccell.2021.02.016 (2021)

Bridged parametric survival models: General paradigm and speed improvements Swihart, BJ; Bandyopadhyay, D; , Comput Methods Programs Biomed, DOI://10.1016/j.cmpb.2021.106115 (2021)
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist Glassman, CR; Su, L; Majri-Morrison, SS et al. Elife, DOI://10.7554/eLife.65777 (2021)
Lack of transgenerational effects of ionizing radiation exposure from the Chernobyl accident Yeager, M; Machiela, MJ; Kothiyal, P et al. Science, DOI://10.1126/science.abg2365 (2021)
A miR-375/YAP axis regulates neuroendocrine differentiation and tumorigenesis in lung carcinoid cells Yang, X; Nanayakkara, J; Claypool, D et al. Sci Rep, DOI://10.1038/s41598-021-89855-4 (2021)
COVID-19-CT-CXR: A Freely Accessible and Weakly Labeled Chest X-Ray and CT Image Collection on COVID-19 From Biomedical Literature Peng, Y; Tang, Y; Lee, S et al. IEEE Trans Big Data, DOI://10.1109/tbdata.2020.3035935 (2021)
Severity modeling of propionic acidemia using clinical and laboratory biomarkers Shchelochkov, OA; Manoli, I; Juneau, P et al. Genet Med, DOI://10.1038/s41436-021-01173-2 (2021)
Common Variable Immunodeficiency, Autoimmune Hemolytic Anemia, and Pancytopenia Associated With a Defect in IKAROS Yilmaz, E; Kuehn, HS; Odakir, E et al. J Pediatr Hematol Oncol, DOI://10.1097/MPH.0000000000001976 (2021)
Small RNAs are modified with N-glycans and displayed on the surface of living cells Flynn, RA; Pedram, K; Malaker, SA et al. Cell, DOI://10.1016/j.cell.2021.04.023 (2021)
Genome-Wide Association Study Meta-Analysis for Parkinson Disease Motor Subtypes Alfradique-Dunham, I; Al-Ouran, R; von Coelln, R et al. Neurol Genet, DOI://10.1212/NXG.0000000000000557 (2021)
Feeding-induced resistance to acute lethal sepsis is dependent on hepatic BMAL1 and FXR signalling Geiger, SS; Traba, J; Richoz, N et al. Nat Commun, DOI://10.1038/s41467-021-22961-z (2021)
Membrane transporter dimerization driven by differential lipid solvation energetics of dissociated and associated states Chadda, R; Bernhardt, N; Kelley, EG et al. Elife, DOI://10.7554/eLife.63288 (2021)
Next generation sequencing for HLA loci in full heritage Pima Indians of Arizona, Part II: HLA-A, -B, and -C with selected non-classical loci at 4-field resolution from whole genome sequences Williams, RC; Koroglu, C; Knowler, WC et al. Hum Immunol, DOI://10.1016/j.humimm.2021.03.013 (2021)
Novel Murine Biomarkers of Radiation Exposure Using An Aptamer-Based Proteomic Technology Sproull, M; Shankavaram, U; Camphausen, K; , Front Pharmacol, DOI://10.3389/fphar.2021.633131 (2021)
SeqEnhDL: sequence-based classification of cell type-specific enhancers using deep learning models Wang, Y; Jaime-Lara, RB; Roy, A et al. BMC Res Notes, DOI://10.1186/s13104-021-05518-7 (2021)
Single nucleus RNA-sequencing defines unexpected diversity of cholinergic neuron types in the adult mouse spinal cord Alkaslasi, MR; Piccus, ZE; Hareendran, S et al. Nat Commun, DOI://10.1038/s41467-021-22691-2 (2021)
Rapid Identification and Evaluation of Neoantigen-reactive T-Cell Receptors From Single Cells Paria, BC; Levin, N; Lowery, FJ et al. J Immunother, DOI://10.1097/CJI.0000000000000342 (2021)
The Extended Eighth-Shell method for periodic boundary conditions with rotational symmetry Prasad, S; Simmonett, AC; Meana-Pañeda, R; Brooks, BR; , J Comput Chem, DOI://10.1002/jcc.26545 (2021)
Germline IKAROS dimerization haploinsufficiency causes hematologic cytopenias and malignancies Kuehn, HS; Niemela, JE; Stoddard, J et al. Blood, DOI://10.1182/blood.2020007292 (2021)

The ribosome modulates folding inside the ribosomal exit tunnel Wruck, F; Tian, P; Kudva, R et al. Commun Biol, DOI://10.1038/s42003-021-02055-8 (2021)
Multimodal Functional Imaging for Cancer/Tumor Microenvironments Based on MRI, EPRI, and PET Matsumoto, KI; Mitchell, JB; Krishna, MC; , Molecules, DOI://10.3390/molecules26061614 (2021)
Author Correction: High-depth African genomes inform human migration and health Choudhury, A; Aron, S; Botigué, LR et al. Nature, DOI://10.1038/s41586-021-03286-9 (2021)
VPS13D promotes peroxisome biogenesis Baldwin, HA; Wang, C; Kanfer, G et al. J Cell Biol, DOI://10.1083/jcb.202001188 (2021)
The causes of Fanconi anemia in South Asia and the Middle East: A case series and review of the literature Thompson, AS; Saba, N; McReynolds, LJ et al. Mol Genet Genomic Med, DOI://10.1002/mgg3.1693 (2021)
Towards complete and error-free genome assemblies of all vertebrate species Rhie, A; McCarthy, SA; Fedrigo, O et al. Nature, DOI://10.1038/s41586-021-03451-0 (2021)

Loss of DLX3 tumor suppressive function promotes progression of SCC through EGFR-ERBB2 pathway Bajpai, D; Mehdizadeh, S; Uchiyama, A et al. Oncogene, DOI://10.1038/s41388-021-01802-9 (2021)
Social Heterogeneity Drives Complex Patterns of the COVID-19 Pandemic: Insights From a Novel Stochastic Heterogeneous Epidemic Model (SHEM) Alexander V. Maltsev & Michael D. Stern* Front. Phys., doi://10.3389/fphy.2020.609224 (2021)
Human Histone Interaction Networks: An Old Concept, New Trends Peng, Y; Markov, Y; Goncearenco, A et al. J Mol Biol, DOI://10.1016/j.jmb.2020.10.018 (2021)
Redundant and non-redundant cytokine-activated enhancers control Csn1s2b expression in the lactating mouse mammary gland Lee, HK; Willi, M; Kuhns, T et al. Nat Commun, DOI://10.1038/s41467-021-22500-w (2021)
FIB-SEM as a Volume Electron Microscopy Approach to Study Cellular Architectures in SARS-CoV-2 and Other Viral Infections: A Practical Primer for a Virologist Baena, V; Conrad, R; Friday, P et al. Viruses, doi://10.3390/v13040611 (2021)
Perfluorooctanoic acid (PFOA) or perfluorooctane sulfonate (PFOS) and DNA methylation in newborn dried blood spots in the Upstate KIDS cohort Robinson, SL; Zeng, X; Guan, W et al. Environ Res, DOI://10.1016/j.envres.2020.110668 (2021)
TOR targets an RNA processing network to regulate facultative heterochromatin, developmental gene expression and cell proliferation Wei, Y; Lee, NN; Pan, L et al. Nat Cell Biol, DOI://10.1038/s41556-021-00631-y (2021)
Threat-anticipatory psychophysiological response is enhanced in youth with anxiety disorders and correlates with prefrontal cortex neuroanatomy Abend, R; Bajaj, MA; Harrewijn, A et al. J Psychiatry Neurosci, DOI://10.1503/jpn.200110 (2021)
Shared and Anxiety-Specific Pediatric Psychopathology Dimensions Manifest Distributed Neural Correlates Linke, JO; Abend, R; Kircanski, K et al. Biol Psychiatry, DOI://10.1016/j.biopsych.2020.10.018 (2021)
Overexpression of Human ABCB1 and ABCG2 Reduces the Susceptibility of Cancer Cells to the Histone Deacetylase 6-Specific Inhibitor Citarinostat Wu, CP; Hung, CY; Lusvarghi, S et al. Int J Mol Sci, DOI://10.3390/ijms22052592 (2021)
Host-Pathogen Interactions in Human Polyomavirus 7‒Associated Pruritic Skin Eruption Rosenstein, RK; Pastrana, DV; Starrett, GJ et al. J Invest Dermatol, DOI://10.1016/j.jid.2020.09.014 (2021)
Morphological integration of the human brain across adolescence and adulthood Nadig, A; Seidlitz, J; McDermott, CL et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2023860118 (2021)
SASH3 variants cause a novel form of X-linked combined immunodeficiency with immune dysregulation Delmonte, OM; Bergerson, JRE; Kawai, T et al. Blood, DOI://10.1182/blood.2020008629 (2021)
Assessment of ANG variants in Parkinson's disease Grenn, FP; Moore, A; Bandres-Ciga, S et al. Neurobiol Aging, DOI://10.1016/j.neurobiolaging.2021.03.006 (2021)
Ketamine Alters Electrophysiological Responses to Emotional Faces in Major Depressive Disorder Lundin, NB; Sepe-Forrest, L; Gilbert, JR et al. J Affect Disord, DOI://10.1016/j.jad.2020.10.007 (2021)
Beam image-shift accelerated data acquisition for near-atomic resolution single-particle cryo-electron tomography Bouvette, J; Liu, HF; Du, X et al. Nat Commun, DOI://10.1038/s41467-021-22251-8 (2021)
The structure, function and evolution of a complete human chromosome 8 Logsdon, GA; Vollger, MR; Hsieh, P et al. Nature, DOI://10.1038/s41586-021-03420-7 (2021)
Synchronous RNA conformational changes trigger ordered phase transitions in crystals Ramakrishnan, S; Stagno, JR; Conrad, CE et al. Nat Commun, DOI://10.1038/s41467-021-21838-5 (2021)

A comprehensive macaque fMRI pipeline and hierarchical atlas Jung, B; Taylor, PA; Seidlitz, J et al. Neuroimage, DOI://10.1016/j.neuroimage.2021.117997 (2021)
Reprogramming of translation in yeast cells impaired for ribosome recycling favors short, efficiently translated mRNAs Gaikwad, S; Ghobakhlou, F; Young, DJ et al. Elife, DOI://10.7554/eLife.64283 (2021)
Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress Thomas, A; Takahashi, N; Rajapakse, VN et al. Cancer Cell, DOI://10.1016/j.ccell.2021.02.014 (2021)
Synthetic lethality-mediated precision oncology via the tumor transcriptome Lee, JS; Nair, NU; Dinstag, G et al. Cell, DOI://10.1016/j.cell.2021.03.030 (2021)
SomatoSim: precision simulation of somatic single nucleotide variants Hawari, MA; Hong, CS; Biesecker, LG; , BMC Bioinformatics, DOI://10.1186/s12859-021-04024-8 (2021)
Functional Anatomy of the Trimer Apex Reveals Key Hydrophobic Constraints That Maintain the HIV-1 Envelope Spike in a Closed State Zhang, P; Kwon, AL; Guzzo, C et al. mBio, DOI://10.1128/mBio.00090-21 (2021)

Beyond linearity in neuroimaging: Capturing nonlinear relationships with application to longitudinal studies Chen, G; Nash, TA; Cole, KM et al. Neuroimage, DOI://10.1016/j.neuroimage.2021.117891 (2021)
CEM500K, a large-scale heterogeneous unlabeled cellular electron microscopy image dataset for deep learning Conrad, R; Narayan, K; Elife, DOI://10.7554/eLife.65894 (2021)
Martini 3: a general purpose force field for coarse-grained molecular dynamics Souza, PCT; Alessandri, R; Barnoud, J et al. Nat Methods, DOI://10.1038/s41592-021-01098-3 (2021)
SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation Yan, B; Freiwald, T; Chauss, D et al. Sci Immunol, DOI://10.1126/sciimmunol.abg0833 (2021)
A transcription-centric model of SNP-age interaction Wang, K; Basu, M; Malin, J; Hannenhalli, S; , PLoS Genet, DOI://10.1371/journal.pgen.1009427 (2021)
Conception by fertility treatment and offspring deoxyribonucleic acid methylation Yeung, EH; Mendola, P; Sundaram, R et al. Fertil Steril, DOI://10.1016/j.fertnstert.2021.03.011 (2021)

Network Analysis and Transcriptome Profiling Identify Autophagic and Mitochondrial Dysfunctions in SARS-CoV-2 Infection Singh, K; Chen, YC; Hassanzadeh, S et al. Front Genet, DOI://10.3389/fgene.2021.599261 (2021)
Genome-wide binding potential and regulatory activity of the glucocorticoid receptor's monomeric and dimeric forms Johnson, TA; Paakinaho, V; Kim, S; Hager, GL; Presman, DM; , Nat Commun, DOI://10.1038/s41467-021-22234-9 (2021)
Predicting tissue-specific gene expression from whole blood transcriptome Basu, M; Wang, K; Ruppin, E; Hannenhalli, S; , Sci Adv, DOI://10.1126/sciadv.abd6991 (2021)
Movie-watching outperforms rest for functional connectivity-based prediction of behavior Finn, ES; Bandettini, PA; , Neuroimage, DOI://10.1016/j.neuroimage.2021.117963 (2021)
Structure-Activity Relationship of Heterocyclic P2Y 14 Receptor Antagonists: Removal of the Zwitterionic Character with Piperidine Bioisosteres Jung, YH; Salmaso, V; Wen, Z et al. J Med Chem, DOI://10.1021/acs.jmedchem.1c00164 (2021)
Nascent Prostate Cancer Heterogeneity Drives Evolution and Resistance to Intense Hormonal Therapy Wilkinson, S; Ye, H; Karzai, F et al. Eur Urol, DOI://10.1016/j.eururo.2021.03.009 (2021)

Thousands of previously unknown phages discovered in whole-community human gut metagenomes Benler, S; Yutin, N; Antipov, D et al. Microbiome, DOI://10.1186/s40168-021-01017-w (2021)
Genomic insights into the host specific adaptation of the Pneumocystis genus Cissé, OH; Ma, L; Dekker, JP et al. Commun Biol, DOI://10.1038/s42003-021-01799-7 (2021)
New insights into modeling exposure measurements below the limit of detection Ortega-Villa, AM; Liu, D; Ward, MH; Albert, PS; , Environ Epidemiol, DOI://10.1097/EE9.0000000000000116 (2021)
The Structural Basis of Akt PH Domain Interaction with Calmodulin Weako, J; Jang, H; Keskin, O; Nussinov, R; Gursoy, A; , Biophys J, DOI://10.1016/j.bpj.2021.03.018 (2021)
The NIMH Intramural Longitudinal Study of the Endocrine and Neurobiological Events Accompanying Puberty: Protocol and Rationale for Methods and Measures Cole, KM; Wei, SM; Martinez, PE et al. Neuroimage, DOI://10.1016/j.neuroimage.2021.117970 (2021)
Performance in even a simple perceptual task depends on mouse secondary visual areas Goldbach, HC; Akitake, B; Leedy, CE; Histed, MH; , Elife, DOI://10.7554/eLife.62156 (2021)

Estimating transition path times and shapes from single-molecule photon trajectories: A simulation analysis Taumoefolau, GH; Best, RB; , J Chem Phys, DOI://10.1063/5.0040949 (2021)
SARS-CoV-2 infection of the oral cavity and saliva Huang, N; Pérez, P; Kato, T et al. Nat Med, DOI://10.1038/s41591-021-01296-8 (2021)
A Comprehensive Map of mRNAs and Their Isoforms across All 14 Renal Tubule Segments of Mouse Chen, L; Chou, CL; Knepper, MA; , J Am Soc Nephrol, DOI://10.1681/ASN.2020101406 (2021)
Integrative analysis of multiple case-control studies Zhang, H; Deng, L; Wheeler, W; Qin, J; Yu, K; , Biometrics, DOI://10.1111/biom.13461 (2021)
Epigenome-wide association study of whole blood gene expression in Framingham Heart Study participants provides molecular insight into the potential role of CHRNA5 in cigarette smoking-related lung diseases Yao, C; Joehanes, R; Wilson, R et al. Clin Epigenetics, DOI://10.1186/s13148-021-01041-5 (2021)
Genetically engineered myeloid cells rebalance the core immune suppression program in metastasis Kaczanowska, S; Beury, DW; Gopalan, V et al. Cell, DOI://10.1016/j.cell.2021.02.048 (2021)

Exploring dynamics and network analysis of spike glycoprotein of SARS-COV-2 Ghorbani, M; Brooks, BR; Klauda, JB; , Biophys J, DOI://10.1016/j.bpj.2021.02.047 (2021)
Genomic diversity of SARS-CoV-2 during early introduction into the Baltimore-Washington metropolitan area Thielen, PM; Wohl, S; Mehoke, T et al. JCI Insight, DOI://10.1172/jci.insight.144350 (2021)
Conformational Ensemble of Tte AdoCbl Riboswitch Provides Stable Structural Elements for Conformation Selection and Population Shift in Cobalamin Recognition Ma, B; Bai, G; Nussinov, R; Ding, J; Wang, YX; , J Phys Chem B, DOI://10.1021/acs.jpcb.1c00038 (2021)
Targeting natural splicing plasticity of APOBEC3B restricts its expression and mutagenic activity Rouf Banday, A; Onabajo, OO; Lin, SH et al. Commun Biol, DOI://10.1038/s42003-021-01844-5 (2021)
Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation Guan, R; Lian, T; Zhou, BR et al. Nat Commun, DOI://10.1038/s41467-021-21985-9 (2021)
Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma Hung, MH; Lee, JS; Ma, C et al. Nat Commun, DOI://10.1038/s41467-021-21804-1 (2021)

Iterative epigenomic analyses in the same single cell Ohnuki, H; Venzon, DJ; Lobanov, A; Tosato, G; , Genome Res, DOI://10.1101/gr.269068.120 (2021)
Correction to: The Haskins pediatric atlas: a magnetic-resonance-imaging-based pediatric template and atlas Molfese, PJ; Glen, D; Mesite, L et al. Pediatr Radiol, DOI://10.1007/s00247-020-04958-w (2021)
Ancestral haplotype reconstruction in endogamous populations using identity-by-descent Finke, K; Kourakos, M; Brown, G et al. PLoS Comput Biol, DOI://10.1371/journal.pcbi.1008638 (2021)
Chloride-dependent conformational changes in the GlyT1 glycine transporter Zhang, YW; Uchendu, S; Leone, V et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2017431118 (2021)
Death agonist antibody against TRAILR2/DR5/TNFRSF10B enhances birinapant anti-tumor activity in HPV-positive head and neck squamous cell carcinomas An, Y; Jeon, J; Sun, L et al. Sci Rep, DOI://10.1038/s41598-021-85589-5 (2021)
Structure of membrane diacylglycerol kinase in lipid bilayers Li, J; Shen, Y; Chen, Y et al. Commun Biol, DOI://10.1038/s42003-021-01802-1 (2021)

Comparative engraftment and clonality of macaque HSPCs expanded on human umbilical vein endothelial cells versus non-expanded cells Srivastava, SK; Truitt, LL; Wu, C et al. Mol Ther Methods Clin Dev, DOI://10.1016/j.omtm.2021.02.009 (2021)
Genetically inferred telomere length and testicular germ cell tumor risk Brown, DW; Lan, Q; Rothman, N et al. Cancer Epidemiol Biomarkers Prev, DOI://10.1158/1055-9965.EPI-20-1775 (2021)
Nascent RNA sequencing identifies a widespread sigma70-dependent pausing regulated by Gre factors in bacteria Sun, Z; Yakhnin, AV; FitzGerald, PC et al. Nat Commun, DOI://10.1038/s41467-021-21150-2 (2021)
Tumor IsomiR Encyclopedia (TIE): a pancancer database of miRNA isoforms Bofill-De Ros, X; Luke, B; Guthridge, R et al. Bioinformatics, DOI://10.1093/bioinformatics/btab172 (2021)
Fully automated CT imaging biomarkers of bone, muscle, and fat: correcting for the effect of intravenous contrast Perez, AA; Pickhardt, PJ; Elton, DC; Sandfort, V; Summers, RM; , Abdom Radiol (NY), DOI://10.1007/s00261-020-02755-5 (2021)
Retroviral Elements in Human Evolution and Neural Development Wang, T; Doucet-O'Hare, TT; Henderson, L et al. J Exp Neurol, 2692-2819 (2021)

B-Raf autoinhibition in the presence and absence of 14-3-3 Zhang, M; Jang, H; Li, Z; Sacks, DB; Nussinov, R; , Structure, DOI://10.1016/j.str.2021.02.005 (2021)
Single-Cell RNA Sequencing Analysis of the Drosophila Larval Ventral Cord Nguyen, TH; Vicidomini, R; Choudhury, SD et al. Curr Protoc, DOI://10.1002/cpz1.38 (2021)
Dose conversion coefficients for neutron external exposures with five postures: walking, sitting, bending, kneeling, and squatting Yeom, YS; Griffin, K; Han, H et al. Radiat Environ Biophys, DOI://10.1007/s00411-021-00900-2 (2021)
Multiplex indexing approach for the detection of DNase I hypersensitive sites in single cells Gao, W; Ku, WL; Pan, L et al. Nucleic Acids Res, DOI://10.1093/nar/gkab102 (2021)
MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23 Mikami, Y; Philips, RL; Sciumè, G et al. Immunity, DOI://10.1016/j.immuni.2021.02.015 (2021)
Mitochondrial Ca 2+, redox environment and ROS emission in heart failure: Two sides of the same coin? Cortassa, S; Juhaszova, M; Aon, MA et al. J Mol Cell Cardiol, DOI://10.1016/j.yjmcc.2020.11.013 (2021)

CHARMM36 Lipid Force Field with Explicit Treatment of Long-Range Dispersion: Parametrization and Validation for Phosphatidylethanolamine, Phosphatidylglycerol, and Ether Lipids Yu, Y; Krämer, A; Venable, RM et al. J Chem Theory Comput, DOI://10.1021/acs.jctc.0c01327 (2021)
Semi-automated Optimization of the CHARMM36 Lipid Force Field to Include Explicit Treatment of Long-Range Dispersion Yu, Y; Krämer, A; Venable, RM et al. J Chem Theory Comput, DOI://10.1021/acs.jctc.0c01326 (2021)
Midbrain activity shapes high-level visual properties in the primate temporal cortex Bogadhi, AR; Katz, LN; Bollimunta, A et al. Neuron, DOI://10.1016/j.neuron.2020.11.023 (2021)
Loop extrusion mediates physiological Igh locus contraction for RAG scanning Dai, HQ; Hu, H; Lou, J et al. Nature, DOI://10.1038/s41586-020-03121-7 (2021)
Mechanism of membrane-tethered mitochondrial protein synthesis Itoh, Y; Andréll, J; Choi, A et al. Science, DOI://10.1126/science.abe0763 (2021)
Gene-based analysis of bi-variate survival traits via functional regressions with applications to eye diseases Zhang, B; Chiu, CY; Yuan, F et al. Genet Epidemiol, DOI://10.1002/gepi.22381 (2021)

BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8 + T cells Yao, C; Lou, G; Sun, HW et al. Nat Immunol, DOI://10.1038/s41590-021-00868-7 (2021)
Lysosome-associated membrane protein 3 misexpression in salivary glands induces a Sjögren's syndrome-like phenotype in mice Nakamura, H; Tanaka, T; Pranzatelli, T et al. Ann Rheum Dis, DOI://10.1136/annrheumdis-2020-219649 (2021)
Structure of an activated DNA-PK and its implications for NHEJ Chen, X; Xu, X; Chen, Y et al. Mol Cell, DOI://10.1016/j.molcel.2020.12.015 (2021)
Does the ATP-bound EQ mutant reflect the pre- or post-ATP hydrolysis state in the catalytic cycle of human P-glycoprotein (ABCB1)? Lusvarghi, S; Durell, SR; Ambudkar, SV; , FEBS Lett, DOI://10.1002/1873-3468.14054 (2021)
Audiovisual integration in macaque face patch neurons Khandhadia, AP; Murphy, AP; Romanski, LM; Bizley, JK; Leopold, DA; , Curr Biol, DOI://10.1016/j.cub.2021.01.102 (2021)
A Genome-First Approach to Characterize DICER1 Pathogenic Variant Prevalence, Penetrance, and Phenotype Mirshahi, UL; Kim, J; Best, AF et al. JAMA Netw Open, DOI://10.1001/jamanetworkopen.2021.0112 (2021)

The Myc-associated zinc finger protein (MAZ) works together with CTCF to control cohesin positioning and genome organization Xiao, T; Li, X; Felsenfeld, G; , Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2023127118 (2021)
Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits Gouveia, MH; Bentley, AR; Leonard, H et al. Sci Rep, DOI://10.1038/s41598-021-83450-3 (2021)
Deep-learning based multi-modal retinal image registration for the longitudinal analysis of patients with age-related macular degeneration De Silva, T; Chew, EY; Hotaling, N; Cukras, CA; , Biomed Opt Express, DOI://10.1364/BOE.408573 (2021)
TRF2-mediated telomere protection is dispensable in pluripotent stem cells Markiewicz-Potoczny, M; Lobanova, A; Loeb, AM et al. Nature, DOI://10.1038/s41586-020-2959-4 (2021)
The yeast ISW1b ATP-dependent chromatin remodeler is critical for nucleosome spacing and dinucleosome resolution Eriksson, PR; Clark, DJ; , Sci Rep, DOI://10.1038/s41598-021-82842-9 (2021)
Smoking modifies pancreatic cancer risk loci on 2q21.3 Mocci, E; Kundu, P; Wheeler, W et al. Cancer Res, DOI://10.1158/0008-5472.CAN-20-3267 (2021)

Exome Sequencing of 21 Bardet-Biedl Syndrome (BBS) Genes to Identify Obesity Variants in 6,851 American Indians Day, SE; Muller, YL; Koroglu, C et al. Obesity (Silver Spring), DOI://10.1002/oby.23115 (2021)
Immune transcriptomes of highly exposed SARS-CoV-2 asymptomatic seropositive versus seronegative individuals from the Ischgl community Lee, HK; Knabl, L; Pipperger, L et al. Sci Rep, DOI://10.1038/s41598-021-83110-6 (2021)
The NF-κB regulator Bcl-3 restricts terminal differentiation and promotes memory cell formation of CD8+ T cells during viral infection Jaiswal, H; Ciucci, T; Wang, H et al. PLoS Pathog, DOI://10.1371/journal.ppat.1009249 (2021)
Gene Therapy of Dominant CRX-Leber Congenital Amaurosis using Patient Stem Cell-Derived Retinal Organoids Kruczek, K; Qu, Z; Gentry, J et al. Stem Cell Reports, DOI://10.1016/j.stemcr.2020.12.018 (2021)
Total Ortholog Median Matrix as an alternative unsupervised approach for phylogenomics based on evolutionary distance between protein coding genes Maruyama, SR; Rogerio, LA; Freitas, PD; Teixeira, MMG; Ribeiro, JMC; , Sci Rep, DOI://10.1038/s41598-021-81926-w (2021)
Dynamic sex chromosome expression in Drosophila male germ cells Mahadevaraju, S; Fear, JM; Akeju, M et al. Nat Commun, DOI://10.1038/s41467-021-20897-y (2021)

Admixture mapping identifies African and Amerindigenous local ancestry loci associated with fetal growth Tekola-Ayele, F; Ouidir, M; Shrestha, D et al. Hum Genet, DOI://10.1007/s00439-021-02265-4 (2021)
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture Chia, R; Sabir, MS; Bandres-Ciga, S et al. Nat Genet, DOI://10.1038/s41588-021-00785-3 (2021)
Genome-wide transcriptome study using deep RNA sequencing for myocardial infarction and coronary artery calcification Zhang, X; van Rooij, JGJ; Wakabayashi, Y et al. BMC Med Genomics, DOI://10.1186/s12920-020-00838-2 (2021)
Assessment of assumptions underlying models of prokaryotic pangenome evolution Sela, I; Wolf, YI; Koonin, EV; , BMC Biol, DOI://10.1186/s12915-021-00960-2 (2021)
Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets Kia, DA; Zhang, D; Guelfi, S et al. JAMA Neurol, DOI://10.1001/jamaneurol.2020.5257 (2021)
Molecular structure of a prevalent amyloid-β fibril polymorph from Alzheimer's disease brain tissue Ghosh, U; Thurber, KR; Yau, WM; Tycko, R; , Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2023089118 (2021)

An open-source python library for detection of known and novel Kell, Duffy and Kidd variants from exome sequencing Montemayor, C; Simone, A; Long, J et al. Vox Sang, DOI://10.1111/vox.13035 (2021)
On the Role of a Conserved Methionine in the Na+-Coupling Mechanism of a Neurotransmitter Transporter Homolog Zhou, W; Trinco, G; Slotboom, DJ; Forrest, LR; Faraldo-Gómez, JD; , Neurochem Res, DOI://10.1007/s11064-021-03253-w (2021)
The genomic structure of a human chromosome 22 nucleolar organizer region determined by TAR cloning Kim, JH; Noskov, VN; Ogurtsov, AY et al. Sci Rep, DOI://10.1038/s41598-021-82565-x (2021)
Deep transcriptome sequencing of subgenual anterior cingulate cortex reveals cross-diagnostic and diagnosis-specific RNA expression changes in major psychiatric disorders Akula, N; Marenco, S; Johnson, K et al. Neuropsychopharmacology, DOI://10.1038/s41386-020-00949-5 (2021)
An examination of the relationships between attention/deficit hyperactivity disorder symptoms and functional connectivity over time Norman, LJ; Sudre, G; Bouyssi-Kobar, M; Sharp, W; Shaw, P; , Neuropsychopharmacology, DOI://10.1038/s41386-021-00958-y (2021)
Trastuzumab Blocks the Receiver Function of HER2 Leading to the Population Shifts of HER2-Containing Homodimers and Heterodimers Zhao, J; Mohan, N; Nussinov, R; Ma, B; Wu, WJ; , Antibodies (Basel), DOI://10.3390/antib10010007 (2021)

Infection trains the host for microbiota-enhanced resistance to pathogens Stacy, A; Andrade-Oliveira, V; McCulloch, JA et al. Cell, DOI://10.1016/j.cell.2020.12.011 (2021)
Active and Inactive Cdc42 Differ in Their Insert Region Conformational Dynamics Haspel, N; Jang, H; Nussinov, R; , Biophys J, DOI://10.1016/j.bpj.2020.12.007 (2021)
Linkage-specific deubiquitylation by OTUD5 defines an embryonic pathway intolerant to genomic variation Beck, DB; Basar, MA; Asmar, AJ et al. Sci Adv, DOI://10.1126/sciadv.abe2116 (2021)
Synthetic lethality across normal tissues is strongly associated with cancer risk, onset, and tumor suppressor specificity Cheng, K; Nair, NU; Lee, JS; Ruppin, E; , Sci Adv, DOI://10.1126/sciadv.abc2100 (2021)
Genetic analysis of amyotrophic lateral sclerosis identifies contributing pathways and cell types Saez-Atienzar, S; Bandres-Ciga, S; Langston, RG et al. Sci Adv, DOI://10.1126/sciadv.abd9036 (2021)
Self-organizing maps with variable neighborhoods facilitate learning of chromatin accessibility signal shapes associated with regulatory elements Eicher, T; Chan, J; Luu, H; Machiraju, R; Mathé, EA; , BMC Bioinformatics, DOI://10.1186/s12859-021-03976-1 (2021)

Associations of maternal blood pressure-raising polygenic risk scores with fetal weight Workalemahu, T; Rahman, ML; Ouidir, M; Wu, J; Zhang, C; Tekola-Ayele, F; , J Hum Hypertens, DOI://10.1038/s41371-021-00483-x (2021)
Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics Pillon, MC; Frazier, MN; Dillard, LB et al. Nat Commun, DOI://10.1038/s41467-020-20608-z (2021)
Dense cellular segmentation for EM using 2D-3D neural network ensembles Guay, MD; Emam, ZAS; Anderson, AB et al. Sci Rep, DOI://10.1038/s41598-021-81590-0 (2021)
An optimized protocol for acquiring and processing cryo-EM data of human 26S proteasome with M1-Ub6 Chen, X; Shi, D; Zhang, P; Walters, KJ; , STAR Protoc, DOI://10.1016/j.xpro.2020.100278 (2021)
A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication Hattori, SI; Higashi-Kuwata, N; Hayashi, H et al. Nat Commun, DOI://10.1038/s41467-021-20900-6 (2021)
Whole-exome sequencing reveals germline-mutated small cell lung cancer subtype with favorable response to DNA repair-targeted therapies Tlemsani, C; Takahashi, N; Pongor, L et al. Sci Transl Med, DOI://10.1126/scitranslmed.abc7488 (2021)

Cenote-Taker 2 democratizes virus discovery and sequence annotation Tisza, MJ; Belford, AK; Domínguez-Huerta, G; Bolduc, B; Buck, CB; , Virus Evol, DOI://10.1093/ve/veaa100 (2021)
Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma Pomella, S; Sreenivas, P; Gryder, BE et al. Nat Commun, DOI://10.1038/s41467-020-20386-8 (2021)
Glycolytic metabolism of pathogenic T cells enables early detection of GVHD by 13C-MRI Assmann, JC; Farthing, DE; Saito, K et al. Blood, DOI://10.1182/blood.2020005770 (2021)
TCF7L2 silencing results in altered gene expression patterns accompanied by local genomic reorganization Brown, MA; Dotson, GA; Ronquist, S; Emons, G; Rajapakse, I; Ried, T; , Neoplasia, DOI://10.1016/j.neo.2020.12.010 (2021)
Overexpression of the Bacteriophage T4 motB Gene Alters H-NS Dependent Repression of Specific Host DNA Patterson-West, J; Tai, CH; Son, B; Hsieh, ML; Iben, JR; Hinton, DM; , Viruses, DOI://10.3390/v13010084 (2021)
Regulatory roles of Escherichia coli 5'UTR and ORF-internal RNAs detected by 3'end mapping Adams, PP; Baniulyte, G; Esnault, C et al. Elife, DOI://10.7554/eLife.62438 (2021)

Survivin Expression is Differentially Regulated by a Selective Crosstalk between Rbm38 and miRNAs let-7b or miR-203a Lucchesi, CA; Zhang, J; Ma, B; Nussinov, R; Chen, X; , Cancer Res, DOI://10.1158/0008-5472.CAN-20-3157 (2021)
Image-based pooled whole-genome CRISPRi screening for subcellular phenotypes Kanfer, G; Sarraf, SA; Maman, Y et al. J Cell Biol, DOI://10.1083/jcb.202006180 (2021)
A Tumor Suppressor Enhancer of PTEN in T-cell development and leukemia Tottone, L; Lancho, O; Loh, JW et al. Blood Cancer Discov, DOI://10.1158/2643-3230.BCD-20-0201 (2021)
A high-throughput predictive method for sequence-similar fold switchers Kim, AK; Looger, LL; Porter, LL; , Biopolymers, DOI://10.1002/bip.23416 (2021)
Marmoset Brain Mapping V3: Population multi-modal standard volumetric and surface-based templates Liu, C; Yen, CC; Szczupak, D; Tian, X; Glen, D; Silva, AC; , Neuroimage, DOI://10.1016/j.neuroimage.2020.117620 (2021)
A collaborative resource platform for non-human primate neuroimaging Messinger, A; Sirmpilatze, N; Heuer, K et al. Neuroimage, DOI://10.1016/j.neuroimage.2020.117519 (2021)

Thymic stromal lymphopoietin limits primary and recall CD8 + T-cell anti-viral responses Ebina-Shibuya, R; West, EE; Spolski, R et al. Elife, DOI://10.7554/eLife.61912 (2021)
Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet-induced diabetes Rodrigues, RR; Gurung, M; Li, Z et al. Nat Commun, DOI://10.1038/s41467-020-20313-x (2021)
Ambulatory Assessment Methods to Examine Momentary State-Based Predictors of Opioid Use Behaviors Burgess-Hull, A; Epstein, DH; , Curr Addict Rep, DOI://10.1007/s40429-020-00351-7 (2021)
Pleiotropic genetic influence on birth weight and childhood obesity Chatterjee, S; Ouidir, M; Tekola-Ayele, F; , Sci Rep, DOI://10.1038/s41598-020-80084-9 (2021)
A population scale analysis of rare SNCA variation in the UK Biobank Blauwendraat, C; Makarious, MB; Leonard, HL et al. Neurobiol Dis, DOI://10.1016/j.nbd.2020.105182 (2021)
Platypus and echidna genomes reveal mammalian biology and evolution Zhou, Y; Shearwin-Whyatt, L; Li, J et al. Nature, DOI://10.1038/s41586-020-03039-0 (2021)

Conserved binding site in the N-lobe of prokaryotic MATE transporters suggests a role for Na + in ion-coupled drug efflux Castellano, S; Claxton, DP; Ficici, E et al. J Biol Chem, DOI://10.1074/jbc.RA120.016792 (2021)
Malaria parasites use a soluble RhopH complex for erythrocyte invasion and an integral form for nutrient uptake Schureck, MA; Darling, JE; Merk, A et al. Elife, DOI://10.7554/eLife.65282 (2021)
Automated assessment of longitudinal biomarker changes at abdominal CT: correlation with subsequent cardiovascular events in an asymptomatic adult screening cohort Graffy, PM; Summers, RM; Perez, AA; Sandfort, V; Zea, R; Pickhardt, PJ; , Abdom Radiol (NY), DOI://10.1007/s00261-020-02885-w (2021)
Great Expectations: A Critical Review of and Suggestions for the Study of Reward Processing as a Cause and Predictor of Depression Nielson, DM; Keren, H; O'Callaghan, G et al. Biol Psychiatry, DOI://10.1016/j.biopsych.2020.06.012 (2021)
END-seq: An Unbiased, High-Resolution, and Genome-Wide Approach to Map DNA Double-Strand Breaks and Resection in Human Cells Wong, N; John, S; Nussenzweig, A; Canela, A; , Methods Mol Biol, DOI://10.1007/978-1-0716-0644-5_2 (2021)

2020 (515 papers)

Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivity Manzella, G; Schreck, LD; Breunis, WB et al. Nat Commun, DOI://10.1038/s41467-020-18388-7 (2020)

Novel, abundant Drosha isoforms are deficient in miRNA processing in cancer cells Dai, L; Hallmark, L; Bofill De Ros, X et al. RNA Biol, DOI://10.1080/15476286.2020.1813439 (2020)
Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations Chen, MH; Raffield, LM; Mousas, A et al. Cell, DOI://10.1016/j.cell.2020.06.045 (2020)
The genomic landscape of Mongolian hepatocellular carcinoma Candia, J; Bayarsaikhan, E; Tandon, M et al. Nat Commun, DOI://10.1038/s41467-020-18186-1 (2020)
Author Correction: Mapping histone modifications in low cell number and single cells using antibody-guided chromatin tagmentation (ACT-seq) Carter, B; Ku, WL; Kang, JY et al. Nat Commun, DOI://10.1038/s41467-020-18309-8 (2020)
The GENDULF algorithm: mining transcriptomics to uncover modifier genes for monogenic diseases Auslander, N; Ramos, DM; Zelaya, I et al. Mol Syst Biol, DOI://10.15252/msb.20209701 (2020)
Exome Sequencing Identifies A Nonsense Variant in DAO Associated With Reduced Energy Expenditure in American Indians Piaggi, P; Köroğlu, Ç; Nair, AK et al. J Clin Endocrinol Metab, DOI://10.1210/clinem/dgaa548 (2020)
Retinal ganglion cell defects cause decision shifts in visually evoked defense responses Lees, RN; Akbar, AF; Badea, TC; , J Neurophysiol, DOI://10.1152/jn.00474.2019 (2020)
In vitro model of perimenopausal depression implicates steroid metabolic and proinflammatory genes Rudzinskas, S; Hoffman, JF; Martinez, P et al. Mol Psychiatry, DOI://10.1038/s41380-020-00860-x (2020)
NusG-dependent RNA polymerase pausing is a frequent function of this universally conserved transcription elongation factor Yakhnin, AV; Kashlev, M; Babitzke, P; , Crit Rev Biochem Mol Biol, DOI://10.1080/10409238.2020.1828261 (2020)
The Genetic Basis of Morphological Diversity in Domesticated Goldfish Kon, T; Omori, Y; Fukuta, K et al. Curr Biol, DOI://10.1016/j.cub.2020.04.034 (2020)
Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma Brudno, JN; Lam, N; Vanasse, D et al. Nat Med, DOI://10.1038/s41591-019-0737-3 (2020)
Genomic analyses of a livestock pest, the New World screwworm, find potential targets for genetic control programs Scott, MJ; Benoit, JB; Davis, RJ et al. Commun Biol, DOI://10.1038/s42003-020-01152-4 (2020)

Transcriptome analysis of desmoplastic small round cell tumors identifies actionable therapeutic targets: a report from the Children's Oncology Group Hingorani, P; Dinu, V; Zhang, X et al. Sci Rep, DOI://10.1038/s41598-020-69015-w (2020)
LSH mediates gene repression through macroH2A deposition Ni, K; Ren, J; Xu, X et al. Nat Commun, DOI://10.1038/s41467-020-19159-0 (2020)
Improved reference genome of the arboviral vector Aedes albopictus Palatini, U; Masri, RA; Cosme, LV et al. Genome Biol, DOI://10.1186/s13059-020-02141-w (2020)
Whole-Exome Profiling of NSCLC Among African Americans Arauz, RF; Byun, JS; Tandon, M et al. J Thorac Oncol, DOI://10.1016/j.jtho.2020.08.029 (2020)
HLA tapasin independence: broader peptide repertoire and HIV control Bashirova, AA; Viard, M; Naranbhai, V et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2013554117 (2020)
Disappearance of the polyelectrolyte peak in salt-free solutions Chremos, A; Horkay, F; , Phys Rev E, DOI://10.1103/PhysRevE.102.012611 (2020)

Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease Beck, DB; Ferrada, MA; Sikora, KA et al. N Engl J Med, DOI://10.1056/NEJMoa2026834 (2020)
Biallelic variants in two complex I genes cause abnormal splicing defects in probands with mild Leigh syndrome Johnstone, T; Wang, J; Ross, D et al. Mol Genet Metab, DOI://10.1016/j.ymgme.2020.09.008 (2020)
Multilayer MEG functional connectivity as a potential marker for suicidal thoughts in major depressive disorder Nugent, AC; Ballard, ED; Gilbert, JR et al. Neuroimage Clin, DOI://10.1016/j.nicl.2020.102378 (2020)
Development and validation of prognostic gene signature for basal-like breast cancer and high-grade serous ovarian cancer Zhang, Y; Liu, J; Raj-Kumar, PK et al. Breast Cancer Res Treat, DOI://10.1007/s10549-020-05884-z (2020)
A Cutibacterium acnes antibiotic modulates human skin microbiota composition in hair follicles Claesen, J; Spagnolo, JB; Ramos, SF et al. Sci Transl Med, DOI://10.1126/scitranslmed.aay5445 (2020)
Therapeutic responses to Roseomonas mucosa in atopic dermatitis may involve lipid-mediated TNF-related epithelial repair Myles, IA; Castillo, CR; Barbian, KD et al. Sci Transl Med, DOI://10.1126/scitranslmed.aaz8631 (2020)
Comparative Transcriptomics Analyses in Livers of Mice, Humans, and Humanized Mice Define Human-Specific Gene Networks Jiang, C; Li, P; Ruan, X et al. Cells, DOI://10.3390/cells9122566 (2020)
IBEX: A versatile multiplex optical imaging approach for deep phenotyping and spatial analysis of cells in complex tissues Radtke, AJ; Kandov, E; Lowekamp, B et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2018488117 (2020)
The Central Role of Salivary Metalloproteases in Host Acquired Resistance to Tick Feeding Perner, J; Helm, D; Haberkant, P et al. Front Cell Infect Microbiol, DOI://10.3389/fcimb.2020.563349 (2020)
Deficiency in the endocytic adaptor proteins PHETA1/2 impairs renal and craniofacial development Ates, KM; Wang, T; Moreland, T et al. Dis Model Mech, DOI://10.1242/dmm.041913 (2020)
APOBEC3A catalyzes mutation and drives carcinogenesis in vivo Law, EK; Levin-Klein, R; Jarvis, MC et al. J Exp Med, DOI://10.1084/jem.20200261 (2020)
Polygenic analysis of the effect of common and low-frequency genetic variants on serum uric acid levels in Korean individuals Cho, SK; Kim, B; Myung, W et al. Sci Rep, DOI://10.1038/s41598-020-66064-z (2020)

Dynamics of genomic and immune responses during primary immunotherapy resistance in mismatch repair-deficient tumors Takahashi, N; Rajapakse, VN; Pongor, L et al. Cold Spring Harb Mol Case Stud, DOI://10.1101/mcs.a005678 (2020)
Systematic investigation of synthetic polyelectrolyte bottlebrush solutions by neutron and dynamic light scattering, osmometry, and molecular dynamics simulation Horkay, F; Chremos, A; Douglas, JF et al. J Chem Phys, DOI://10.1063/5.0007271 (2020)
Sex chromosome and sex locus characterization in goldfish, Carassius auratus (Linnaeus, 1758) Wen, M; Feron, R; Pan, Q et al. BMC Genomics, DOI://10.1186/s12864-020-06959-3 (2020)
Structural insight into toxin secretion by contact-dependent growth inhibition transporters Guerin, J; Botos, I; Zhang, Z et al. Elife, DOI://10.7554/eLife.58100 (2020)
An RNA Repair Operon Regulated by Damaged tRNAs Hughes, KJ; Chen, X; Burroughs, AM et al. Cell Rep, DOI://10.1016/j.celrep.2020.108527 (2020)
Effect of sequence depth and length in long-read assembly of the maize inbred NC358 Ou, S; Liu, J; Chougule, KM et al. Nat Commun, DOI://10.1038/s41467-020-16037-7 (2020)
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci de Las Fuentes, L; Sung, YJ; Noordam, R et al. Mol Psychiatry, DOI://10.1038/s41380-020-0719-3 (2020)
Rapid image deconvolution and multiview fusion for optical microscopy Guo, M; Li, Y; Su, Y et al. Nat Biotechnol, DOI://10.1038/s41587-020-0560-x (2020)
Language lateralization from task-based and resting state functional MRI in patients with epilepsy Rolinski, R; You, X; Gonzalez-Castillo, J et al. Hum Brain Mapp, DOI://10.1002/hbm.25003 (2020)
Strains used in whole organism Plasmodium falciparum vaccine trials differ in genome structure, sequence, and immunogenic potential Moser, KA; Drábek, EF; Dwivedi, A et al. Genome Med, DOI://10.1186/s13073-019-0708-9 (2020)
A Serum Proteomic Signature Predicting Survival in Patients with Glioblastoma Sproull, M; Mathen, P; Miller, CA et al. J Biochem Anal Stud, DOI://10.16966/2576-5833.117 (2020)
Impact of Conditioning Intensity of Allogeneic Transplantation for Acute Myeloid Leukemia With Genomic Evidence of Residual Disease Hourigan, CS; Dillon, LW; Gui, G et al. J Clin Oncol, DOI://10.1200/JCO.19.03011 (2020)

Uncoupling the Folding-Function Paradigm of Lytic Peptides to Deliver Impermeable Inhibitors of Intracellular Protein-Protein Interactions Miller, SE; Tsuji, K; Abrams, RPM et al. J Am Chem Soc, DOI://10.1021/jacs.0c07921 (2020)
COVID-19 reopening strategies at the county level in the face of uncertainty: Multiple Models for Outbreak Decision Support Shea, K; Borchering, RK; Probert, WJM et al. medRxiv, DOI://10.1101/2020.11.03.20225409 (2020)
Genome-Wide Analysis of the FOXA1 Transcriptional Network Identifies Novel Protein-Coding and Long Noncoding RNA Targets in Colorectal Cancer Cells Lazar, SB; Pongor, L; Li, XL et al. Mol Cell Biol, DOI://10.1128/MCB.00224-20 (2020)
Somatic structural variation targets neurodevelopmental genes and identifies SHANK2 as a tumor suppressor in neuroblastoma Lopez, G; Conkrite, KL; Doepner, M et al. Genome Res, DOI://10.1101/gr.252106.119 (2020)
Use of word and graph embedding to measure semantic relatedness between Unified Medical Language System concepts Mao, Y; Fung, KW; , J Am Med Inform Assoc, DOI://10.1093/jamia/ocaa136 (2020)
Zebrafish Posterior Lateral Line primordium migration requires interactions between a superficial sheath of motile cells and the skin Dalle Nogare, DE; Natesh, N; Vishwasrao, HD et al. Elife, DOI://10.7554/eLife.58251 (2020)
bZIP Dimers CREB1, ATF2, Zta, ATF3|cJun, and cFos|cJun Prefer to Bind to Some Double-Stranded DNA Sequences Containing 5-Formylcytosine and 5-Carboxylcytosine Ray, S; Tillo, D; Ufot, A et al. Biochemistry, DOI://10.1021/acs.biochem.0c00475 (2020)
Lipid flip-flop and desorption from supported lipid bilayers is independent of curvature Jing, H; Wang, Y; Desai, PR et al. PLoS One, DOI://10.1371/journal.pone.0244460 (2020)
Repeat expansions confer WRN dependence in microsatellite-unstable cancers van Wietmarschen, N; Sridharan, S; Nathan, WJ et al. Nature, DOI://10.1038/s41586-020-2769-8 (2020)
Metabolic but not transcriptional regulation by PKM2 is important for natural killer cell responses Walls, JF; Subleski, JJ; Palmieri, EM et al. Elife, DOI://10.7554/eLife.59166 (2020)
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 Zhang, Q; Bastard, P; Liu, Z et al. Science, DOI://10.1126/science.abd4570 (2020)
mRNA vaccine-induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer Cafri, G; Gartner, JJ; Zaks, T et al. J Clin Invest, DOI://10.1172/JCI134915 (2020)
Age and Tumor Differentiation-Associated Gene Expression Based Analysis of Non-Familial Prostate Cancers Sharad, S; Allemang, TC; Li, H et al. Front Oncol, DOI://10.3389/fonc.2020.584280 (2020)
NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency Marques, JG; Gryder, BE; Pavlovic, B et al. Elife, DOI://10.7554/eLife.54993 (2020)
Scale-Free Dynamics in Animal Groups and Brain Networks Ribeiro, TL; Chialvo, DR; Plenz, D; , Front Syst Neurosci, DOI://10.3389/fnsys.2020.591210 (2020)
Progressive B Cell Loss in Revertant X-SCID Lin, CH; Kuehn, HS; Thauland, TJ et al. J Clin Immunol, DOI://10.1007/s10875-020-00825-3 (2020)
Correction to: A Nonsense N -Terminus NFKB2 Mutation Leading to Haploinsufficiency in a Patient with a Predominantly Antibody Deficiency Kuehn, HS; Bernasconi, A; Niemela, JE et al. J Clin Immunol, DOI://10.1007/s10875-020-00860-0 (2020)
Case Report: Single-Cell Transcriptomic Analysis of an Anaplastic Oligodendroglioma Post Immunotherapy Yu, G; Butler, MK; Abdelmaksoud, A et al. Front Oncol, DOI://10.3389/fonc.2020.601452 (2020)
Integrated analysis of genome-wide miRNAs and targeted gene expression in esophageal squamous cell carcinoma (ESCC) and relation to prognosis Yang, H; Su, H; Hu, N et al. BMC Cancer, DOI://10.1186/s12885-020-06901-6 (2020)
G-Protein biased opioid agonists: 3-hydroxy- N-phenethyl-5-phenylmorphans with three-carbon chain substituents at C9 Gutman, ES; Bow, E; Li, F et al. RSC Med Chem, DOI://10.1039/d0md00104j (2020)
Author Correction: Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma Brudno, JN; Lam, N; Vanasse, D et al. Nat Med, DOI://10.1038/s41591-020-0864-x (2020)
Mutations in CERKL and RP1 cause retinitis pigmentosa in Pakistani families Nadeem, R; Kabir, F; Li, J et al. Hum Genome Var, DOI://10.1038/s41439-020-0100-8 (2020)
Emx2 regulates hair cell rearrangement but not positional identity within neuromasts Ohta, S; Ji, YR; Martin, D; Wu, DK; , Elife, DOI://10.7554/eLife.60432 (2020)
NCINM: organ dose calculator for patients undergoing nuclear medicine procedures Villoing, D; Cuthbert, TA; Kitahara, CM; Lee, C; , Biomed Phys Eng Express, DOI://10.1088/2057-1976/aba41e (2020)

Genetic determinants of survival in progressive supranuclear palsy: a genome-wide association study Jabbari, E; Koga, S; Valentino, RR et al. Lancet Neurol, DOI://10.1016/S1474-4422(20)30394-X (2020)
Assessment of LIN28A variants in Parkinson's disease in large European cohorts Diez-Fairen, M; Makarious, MB; Bandres-Ciga, S; Blauwendraat, C; , ; , Neurobiol Aging, DOI://10.1016/j.neurobiolaging.2020.12.002 (2020)
Gene Expression Profiling of Mediastinal Gray Zone Lymphoma and Its Relationship to Primary Mediastinal B-cell Lymphoma and Classical Hodgkin Lymphoma Pittaluga, S; Nicolae, A; Wright, GW et al. Blood Cancer Discov, DOI://10.1158/2643-3230.BCD-20-0009 (2020)
Loss of myeloid-specific lamin A/C drives lung metastasis through Gfi-1 and C/EBPε-mediated granulocytic differentiation Ishii, H; Park, WY; So, J et al. Mol Carcinog, DOI://10.1002/mc.23147 (2020)
Synthetic Lethal Drug Combinations Targeting Proteasome and Histone Deacetylase Inhibitors in TP53-Mutated Cancers Das, S; Deng, X; Camphausen, K; Shankavaram, U; , Arch Cancer Biol Ther (2020)
PAX1 is essential for development and function of the human thymus Yamazaki, Y; Urrutia, R; Franco, LM et al. Sci Immunol, DOI://10.1126/sciimmunol.aax1036 (2020)

A three-dimensional potential of mean force to improve backbone and sidechain hydrogen bond geometry in Xplor-NIH protein structure determination Schwieters, CD; Bermejo, GA; Clore, GM; , Protein Sci, DOI://10.1002/pro.3745 (2020)
IRBIT Directs Differentiation of Intestinal Stem Cell Progeny to Maintain Tissue Homeostasis Arnaoutov, A; Lee, H; Plevock Haase, K et al. iScience, DOI://10.1016/j.isci.2020.100954 (2020)
Longitudinal changes in network homogeneity in presymptomatic C9orf72 mutation carriers Waugh, RE; Danielian, LE; Shoukry, RFS; Floeter, MK; , Neurobiol Aging, DOI://10.1016/j.neurobiolaging.2020.11.014 (2020)
Progressive multifocal leukoencephalopathy lesion and brain parenchymal segmentation from MRI using serial deep convolutional neural networks Al-Louzi, O; Roy, S; Osuorah, I et al. Neuroimage Clin, DOI://10.1016/j.nicl.2020.102499 (2020)
Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis Dewan, R; Chia, R; Ding, J et al. Neuron, DOI://10.1016/j.neuron.2020.11.005 (2020)
The Evolutionary Dynamics of Influenza A Viruses Circulating in Mallards in Duck Hunting Preserves in Maryland, USA Trovão, NS; Nolting, JM; Slemons, RD; Nelson, MI; Bowman, AS; , Microorganisms, DOI://10.3390/microorganisms9010040 (2020)

Enhancing Question Answering by Injecting Ontological Knowledge through Regularization Goodwin, TR; Demner-Fushman, D; , Proc Conf Empir Methods Nat Lang Process, DOI://10.18653/v1/2020.deelio-1.7 (2020)
Towards Zero-Shot Conditional Summarization with Adaptive Multi-Task Fine-Tuning Goodwin, TR; Savery, ME; Demner-Fushman, D; , Proc Conf Empir Methods Nat Lang Process (2020)
Matrix Drug Screen Identifies Synergistic Drug Combinations to Augment SMAC Mimetic Activity in Ovarian Cancer Noonan, AM; Cousins, A; Anderson, D et al. Cancers (Basel), DOI://10.3390/cancers12123784 (2020)
Molecular Details of Protein Condensates Probed by Microsecond Long Atomistic Simulations Zheng, W; Dignon, GL; Jovic, N et al. J Phys Chem B, DOI://10.1021/acs.jpcb.0c10489 (2020)
Loss of endocytosis-associated RabGEF1 causes aberrant morphogenesis and altered autophagy in photoreceptors leading to retinal degeneration Hargrove-Grimes, P; Mondal, AK; Gumerson, J et al. PLoS Genet, DOI://10.1371/journal.pgen.1009259 (2020)
Evolving schema representations in orbitofrontal ensembles during learning Zhou, J; Jia, C; Montesinos-Cartagena, M; Gardner, MPH; Zong, W; Schoenbaum, G; , Nature, DOI://10.1038/s41586-020-03061-2 (2020)

Seeker: alignment-free identification of bacteriophage genomes by deep learning Auslander, N; Gussow, AB; Benler, S; Wolf, YI; Koonin, EV; , Nucleic Acids Res, DOI://10.1093/nar/gkaa856 (2020)
Cancer prognosis with shallow tumor RNA sequencing Milanez-Almeida, P; Martins, AJ; Germain, RN; Tsang, JS; , Nat Med, DOI://10.1038/s41591-019-0729-3 (2020)
LAMP3 induces apoptosis and autoantigen release in Sjögren's syndrome patients Tanaka, T; Warner, BM; Odani, T et al. Sci Rep, DOI://10.1038/s41598-020-71669-5 (2020)
Disseminated Mycobacterium marinum in HIV unmasked by Immune Reconstitution Inflammatory Syndrome Manion, M; Dulanto Chiang, A; Pei, L et al. J Infect Dis, DOI://10.1093/infdis/jiaa769 (2020)
Resting State Functional Connectivity Is Decreased Globally Across the C9orf72 Mutation Spectrum Smallwood Shoukry, RF; Clark, MG; Floeter, MK; , Front Neurol, DOI://10.3389/fneur.2020.598474 (2020)
An Integrated Epigenomic and Transcriptomic Map of Mouse and Human αβ T Cell Development Chopp, LB; Gopalan, V; Ciucci, T et al. Immunity, DOI://10.1016/j.immuni.2020.10.024 (2020)

Identification of a novel long-acting 4'-modified nucleoside reverse transcriptase inhibitor against HBV Higashi-Kuwata, N; Hayashi, S; Kumamoto, H et al. J Hepatol, DOI://10.1016/j.jhep.2020.12.006 (2020)
A Deep Learning Pipeline for Nucleus Segmentation Zaki, G; Gudla, PR; Lee, K et al. Cytometry A, DOI://10.1002/cyto.a.24257 (2020)
Identification of a pathogenic intronic KIF5A mutation in an ALS-FTD kindred Saez-Atienzar, S; Dalgard, CL; Ding, J et al. Neurology, DOI://10.1212/WNL.0000000000011064 (2020)
Ubiquitination of MHC Class II by March-I Regulates Dendritic Cell Fitness Kim, HJ; Bandola-Simon, J; Ishido, S et al. J Immunol, DOI://10.4049/jimmunol.2000975 (2020)
Peptide-MHC Binding Reveals Conserved Allosteric Sites in MHC Class I- and Class II-Restricted T Cell Receptors (TCRs) He, Y; Agnihotri, P; Rangarajan, S et al. J Mol Biol, DOI://10.1016/j.jmb.2020.10.031 (2020)
Generation of a Single-Cell RNAseq Atlas of Murine Salivary Gland Development Hauser, BR; Aure, MH; Kelly, MC; , ; Hoffman, MP; Chibly, AM; , iScience, DOI://10.1016/j.isci.2020.101838 (2020)

Plasma proteomic biomarker signature of age predicts health and life span Tanaka, T; Basisty, N; Fantoni, G et al. Elife, DOI://10.7554/eLife.61073 (2020)
Flight of the PEGASUS? Comparing Transformers on Few-Shot and Zero-Shot Multi-document Abstractive Summarization Goodwin, TR; Savery, ME; Demner-Fushman, D; , Proc Int Conf Comput Ling, 1525-2477 (2020)
Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer Krishna, S; Lowery, FJ; Copeland, AR et al. Science, DOI://10.1126/science.abb9847 (2020)
Data sets on human histone interaction networks Peng, Y; Markov, Y; Goncearenco, A et al. Data Brief, DOI://10.1016/j.dib.2020.106555 (2020)
Identification of Genes Contributing to a Long Circadian Period in Drosophila Melanogaster Kumar, S; Tunc, I; Tansey, TR; Pirooznia, M; Harbison, ST; , J Biol Rhythms, DOI://10.1177/0748730420975946 (2020)
Natural selection on sleep duration in Drosophila melanogaster Souto-Maior, C; Serrano Negron, YL; Harbison, ST; , Sci Rep, DOI://10.1038/s41598-020-77680-0 (2020)

Polyelectrolyte interactions enable rapid association and dissociation in high-affinity disordered protein complexes Sottini, A; Borgia, A; Borgia, MB et al. Nat Commun, DOI://10.1038/s41467-020-18859-x (2020)
Molecular structure and interactions within amyloid-like fibrils formed by a low-complexity protein sequence from FUS Lee, M; Ghosh, U; Thurber, KR; Kato, M; Tycko, R; , Nat Commun, DOI://10.1038/s41467-020-19512-3 (2020)
Feedforward prediction error signals during episodic memory retrieval Haque, RU; Inati, SK; Levey, AI; Zaghloul, KA; , Nat Commun, DOI://10.1038/s41467-020-19828-0 (2020)
Computational Investigation of Gantenerumab and Crenezumab Recognition of Aβ Fibrils in Alzheimer's Disease Brain Tissue Chen, Y; Wei, G; Zhao, J; Nussinov, R; Ma, B; , ACS Chem Neurosci, DOI://10.1021/acschemneuro.0c00364 (2020)
Reliable segmentation of 2D cardiac magnetic resonance perfusion image sequences using time as the 3rd dimension Sandfort, V; Jacobs, M; Arai, AE; Hsu, LY; , Eur Radiol, DOI://10.1007/s00330-020-07474-5 (2020)
A generalized workflow for conducting electric field-optimized, fMRI-guided, transcranial magnetic stimulation Balderston, NL; Roberts, C; Beydler, EM et al. Nat Protoc, DOI://10.1038/s41596-020-0387-4 (2020)

Emergence of non-canonical parvalbumin-containing interneurons in hippocampus of a murine model of type I lissencephaly Ekins, TG; Mahadevan, V; Zhang, Y et al. Elife, DOI://10.7554/eLife.62373 (2020)
Distinct Structures and Dynamics of Chromatosomes with Different Human Linker Histone Isoforms Zhou, BR; Feng, H; Kale, S et al. Mol Cell, DOI://10.1016/j.molcel.2020.10.038 (2020)
A series of five population-specific Indian brain templates and atlases spanning ages 6-60 years Holla, B; Taylor, PA; Glen, DR et al. Hum Brain Mapp, DOI://10.1002/hbm.25182 (2020)
A Heterogeneous Swine Show Circuit Drives Zoonotic Transmission of Influenza A Viruses in the United States Nelson, MI; Perofsky, A; McBride, DS et al. J Virol, DOI://10.1128/JVI.01453-20 (2020)
Novel TMEM98, MFRP, PRSS56 variants in a large United States high hyperopia and nanophthalmos cohort Prasov, L; Guan, B; Ullah, E et al. Sci Rep, DOI://10.1038/s41598-020-76725-8 (2020)
An immune-based biomarker signature is associated with mortality in COVID-19 patients Abers, MS; Delmonte, OM; Ricotta, EE et al. JCI Insight, DOI://10.1172/jci.insight.144455 (2020)

Neanderthal-derived genetic variation is associated with functional connectivity in the brains of living humans Gregory, MD; Kippenhan, JS; Kohn, P et al. Brain Connect, DOI://10.1089/brain.2020.0809 (2020)
SAVI, in silico generation of billions of easily synthesizable compounds through expert-system type rules Patel, H; Ihlenfeldt, WD; Judson, PN et al. Sci Data, DOI://10.1038/s41597-020-00727-4 (2020)
Network Changes in Insula and Amygdala Connectivity Accompany Implicit Suicidal Associations Ballard, ED; Gilbert, JR; Fields, JS; Nugent, AC; Zarate, CA; , Front Psychiatry, DOI://10.3389/fpsyt.2020.577628 (2020)
Statistical approaches using longitudinal biomarkers for disease early detection: A comparison of methodologies Han, Y; Albert, PS; Berg, CD; Wentzensen, N; Katki, HA; Liu, D; , Stat Med, DOI://10.1002/sim.8731 (2020)
The sialotranscriptome of the gopher-tortoise tick, Amblyomma tuberculatum Karim, S; Kumar, D; Adamson, S; Ennen, JR; Qualls, CP; Ribeiro, JMC; , Ticks Tick Borne Dis, DOI://10.1016/j.ttbdis.2020.101560 (2020)
Lack of pathogenic germline DICER1 variants in males with testicular germ-cell tumors Vasta, LM; McMaster, ML; Harney, LA et al. Cancer Genet, DOI://10.1016/j.cancergen.2020.10.002 (2020)
Author Correction: Cryo-EM structure of the bacterial Ton motor subcomplex ExbB-ExbD provides information on structure and stoichiometry Celia, H; Botos, I; Ni, X et al. Commun Biol, DOI://10.1038/s42003-020-01427-w (2020)
Accommodation of In-Register N-Linked Glycans on Prion Protein Amyloid Cores Artikis, E; Roy, A; Verli, H; Cordeiro, Y; Caughey, B; , ACS Chem Neurosci, DOI://10.1021/acschemneuro.0c00635 (2020)
Coarse-grained modelling of DNA plectoneme pinning in the presence of base-pair mismatches Desai, PR; Brahmachari, S; Marko, JF; Das, S; Neuman, KC; , Nucleic Acids Res, DOI://10.1093/nar/gkaa836 (2020)
Predicting the course of ADHD symptoms through the integration of childhood genomic, neural, and cognitive features Sudre, G; Sharp, W; Kundzicz, P et al. Mol Psychiatry, DOI://10.1038/s41380-020-00941-x (2020)
Reversing the direction of drug transport mediated by the human multidrug transporter P-glycoprotein Sajid, A; Lusvarghi, S; Murakami, M et al. Proc Natl Acad Sci U S A, DOI://10.1073/pnas.2016270117 (2020)
Rapid Enhancer Remodeling and Transcription Factor Repurposing Enable High Magnitude Gene Induction upon Acute Activation of NK Cells Sciumè, G; Mikami, Y; Jankovic, D et al. Immunity, DOI://10.1016/j.immuni.2020.09.008 (2020)

Patients with anxiety disorders rely on bilateral dlPFC activation during verbal working memory Balderston, NL; Flook, E; Hsiung, A et al. Soc Cogn Affect Neurosci, DOI://10.1093/scan/nsaa146 (2020)
Genetically predicted telomere length is associated with clonal somatic copy number alterations in peripheral leukocytes Brown, DW; Lin, SH; Loh, PR; Chanock, SJ; Savage, SA; Machiela, MJ; , PLoS Genet, DOI://10.1371/journal.pgen.1009078 (2020)
Characterizing transcriptional regulatory sequences in coronaviruses and their role in recombination Yang, Y; Yan, W; Hall, AB; Jiang, X; , Mol Biol Evol, DOI://10.1093/molbev/msaa281 (2020)
Vestibular phenotype-genotype correlation in a cohort of 90 patients with Usher syndrome Wafa, TT; Faridi, R; King, KA et al. Clin Genet, DOI://10.1111/cge.13868 (2020)
FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age García-Prat, L; Perdiguero, E; Alonso-Martín, S et al. Nat Cell Biol, DOI://10.1038/s41556-020-00593-7 (2020)
Mouse Models of Human Pathogenic Variants of TBC1D24 Associated with Non-Syndromic Deafness DFNB86 and DFNA65 and Syndromes Involving Deafness Tona, R; Lopez, IA; Fenollar-Ferrer, C et al. Genes (Basel), DOI://10.3390/genes11101122 (2020)

Prevalent and sex-biased breathing patterns modify functional connectivity MRI in young adults Lynch, CJ; Silver, BM; Dubin, MJ et al. Nat Commun, DOI://10.1038/s41467-020-18974-9 (2020)
Transcriptomes of Major Proximal Tubule Cell Culture Models Khundmiri, SJ; Chen, L; Lederer, ED; Yang, CR; Knepper, MA; , J Am Soc Nephrol, DOI://10.1681/ASN.2020010009 (2020)
Tumor Phylogeny Topology Inference via Deep Learning Sadeqi Azer, E; Haghir Ebrahimabadi, M; Malikić, S et al. iScience, DOI://10.1016/j.isci.2020.101655 (2020)
Critical Sequence Hotspots for Binding of Novel Coronavirus to Angiotensin Converter Enzyme as Evaluated by Molecular Simulations Ghorbani, M; Brooks, BR; Klauda, JB; , J Phys Chem B, DOI://10.1021/acs.jpcb.0c05994 (2020)
Cancer-Specific Immune Prognostic Signature in Solid Tumors and Its Relation to Immune Checkpoint Therapies Das, S; Camphausen, K; Shankavaram, U; , Cancers (Basel), DOI://10.3390/cancers12092476 (2020)
A physiologic overview of the organ-specific transcriptome of the cattle tick Rhipicephalus microplus Tirloni, L; Braz, G; Nunes, RD et al. Sci Rep, DOI://10.1038/s41598-020-75341-w (2020)

An optimized protocol for retina single-cell RNA sequencing Fadl, BR; Brodie, SA; Malasky, M et al. Mol Vis, 1090-0535 (2020)
Distinct contributions of cathelin-related antimicrobial peptide (CRAMP) derived from epithelial cells and macrophages to colon mucosal homeostasis Chen, K; Yoshimura, T; Yao, X et al. J Pathol, DOI://10.1002/path.5572 (2020)
Embryonic erythropoiesis and hemoglobin switching require transcriptional repressor ETO2 to modulate chromatin organization Guo, X; Plank-Bazinet, J; Krivega, I; Dale, RK; Dean, A; , Nucleic Acids Res, DOI://10.1093/nar/gkaa736 (2020)
Characterization of rare spindle and root cell transcriptional profiles in the stria vascularis of the adult mouse cochlea Gu, S; Olszewski, R; Taukulis, I et al. Sci Rep, DOI://10.1038/s41598-020-75238-8 (2020)
Permutation inference for canonical correlation analysis Winkler, AM; Renaud, O; Smith, SM; Nichols, TE; , Neuroimage, DOI://10.1016/j.neuroimage.2020.117065 (2020)
RNA-sequencing of the Nyssomyia neivai sialome: a sand fly-vector from a Brazilian endemic area for tegumentary leishmaniasis and pemphigus foliaceus Vernal, S; Oliveira, F; Oliveira, WHC et al. Sci Rep, DOI://10.1038/s41598-020-74343-y (2020)

Whole genome sequencing data of multiple individuals of Pakistani descent Khan, SY; Ali, M; Lee, MW et al. Sci Data, DOI://10.1038/s41597-020-00664-2 (2020)
Direct Comparison of (N)-Methanocarba and Ribose-Containing 2-Arylalkynyladenosine Derivatives as A 3 Receptor Agonists Tosh, DK; Salmaso, V; Rao, H et al. ACS Med Chem Lett, DOI://10.1021/acsmedchemlett.9b00637 (2020)
Exploring the sequence fitness landscape of a bridge between protein folds Tian, P; Best, RB; , PLoS Comput Biol, DOI://10.1371/journal.pcbi.1008285 (2020)
lncRNAKB, a knowledgebase of tissue-specific functional annotation and trait association of long noncoding RNA Seifuddin, F; Singh, K; Suresh, A et al. Sci Data, DOI://10.1038/s41597-020-00659-z (2020)
Using whole-exome sequencing and protein interaction networks to prioritize candidate genes for germline cutaneous melanoma susceptibility Yepes, S; Tucker, MA; Koka, H et al. Sci Rep, DOI://10.1038/s41598-020-74293-5 (2020)
Long-Term Cocaine Self-administration Produces Structural Brain Changes That Correlate With Altered Cognition Jedema, HP; Song, X; Aizenstein, HJ et al. Biol Psychiatry, DOI://10.1016/j.biopsych.2020.08.008 (2020)

Interferons and viruses induce a novel truncated ACE2 isoform and not the full-length SARS-CoV-2 receptor Onabajo, OO; Banday, AR; Stanifer, ML et al. Nat Genet, DOI://10.1038/s41588-020-00731-9 (2020)
Low-frequency variation near common germline susceptibility loci are associated with risk of Ewing sarcoma Lin, SH; Sampson, JN; Grünewald, TGP et al. PLoS One, DOI://10.1371/journal.pone.0237792 (2020)
Dynamic Suppression of Average Facial Structure Shapes Neural Tuning in Three Macaque Face Patches Koyano, KW; Jones, AP; McMahon, DBT; Waidmann, EN; Russ, BE; Leopold, DA; , Curr Biol, DOI://10.1016/j.cub.2020.09.070 (2020)
Response nonlinearities in networks of spiking neurons Sanzeni, A; Histed, MH; Brunel, N; , PLoS Comput Biol, DOI://10.1371/journal.pcbi.1008165 (2020)
Body-size-dependent Iodine-131 S values Yeom, YS; Griffin, KT; Shin, B; Choi, C; Han, H; Moon, S; , J Radiol Prot, DOI://10.1088/1361-6498/abc053 (2020)
Structural snapshots of the cellular folded protein translocation machinery Bcs1 Xia, D FEBS J, DOI://10.1111/febs.15576 (2020)

Androgen receptor signaling regulates the transcriptome of prostate cancer cells by modulating global alternative splicing Shah, K; Gagliano, T; Garland, L et al. Oncogene, DOI://10.1038/s41388-020-01429-2 (2020)
Activation of the SARS-CoV-2 Receptor Ace2 through JAK/STAT-Dependent Enhancers during Pregnancy Hennighausen, L; Lee, HK; , Cell Rep, DOI://10.1016/j.celrep.2020.108199 (2020)
Exponential-Family Random Graph Models for Multi-Layer Networks Krivitsky, PN; Koehly, LM; Marcum, CS; , Psychometrika, DOI://10.1007/s11336-020-09720-7 (2020)
Transcriptomic profiling of the digestive tract of the rat flea, Xenopsylla cheopis, following blood feeding and infection with Yersinia pestis Bland, DM; Martens, CA; Virtaneva, K et al. PLoS Negl Trop Dis, DOI://10.1371/journal.pntd.0008688 (2020)
Genetic rescue of X-linked retinoschisis mouse (Rs1-/y) retina induces quiescence of the retinal microglial inflammatory state following AAV8-RS1 gene transfer and identifies gene networks underlying retinal recovery Vijayasarathy, C; Zeng, Y; Brooks, M; Fariss, RN; Sieving, PA; , Hum Gene Ther, DOI://10.1089/hum.2020.213 (2020)
Membrane permeability of small molecules from unbiased molecular dynamics simulations Krämer, A; Ghysels, A; Wang, E et al. J Chem Phys, DOI://10.1063/5.0013429 (2020)

Multiple capsid protein binding sites mediate selective packaging of the alphavirus genomic RNA Brown, RS; Anastasakis, DG; Hafner, M; Kielian, M; , Nat Commun, DOI://10.1038/s41467-020-18447-z (2020)
Deregulated immune cell recruitment orchestrated by FOXM1 impairs human diabetic wound healing Sawaya, AP; Stone, RC; Brooks, SR et al. Nat Commun, DOI://10.1038/s41467-020-18276-0 (2020)
Single-Cell RNA-Sequencing From Mouse Incisor Reveals Dental Epithelial Cell-Type Specific Genes Chiba, Y; Saito, K; Martin, D et al. Front Cell Dev Biol, DOI://10.3389/fcell.2020.00841 (2020)
Projected Cancer Risks to Residents of New Mexico from Exposure to Trinity Radioactive Fallout Cahoon, EK; Zhang, R; Simon, SL; Bouville, A; Pfeiffer, RM; , Health Phys, DOI://10.1097/HP.0000000000001333 (2020)
Merqury: reference-free quality, completeness, and phasing assessment for genome assemblies Rhie, A; Walenz, BP; Koren, S; Phillippy, AM; , Genome Biol, DOI://10.1186/s13059-020-02134-9 (2020)
Synthetic lethal combination targeting BET uncovered intrinsic susceptibility of TNBC to ferroptosis Verma, N; Vinik, Y; Saroha, A et al. Sci Adv, DOI://10.1126/sciadv.aba8968 (2020)
Polygenic risk score for the prediction of breast cancer is related to lesser terminal duct lobular unit involution of the breast Bodelon, C; Oh, H; Derkach, A et al. , DOI://10.1038/s41523-020-00184-7 (2020)
Hybrid-DCA: A double asynchronous approach for stochastic dual coordinate ascent Pal, S; Xu, T; Yang, T; Rajasekaran, S; Bi, J; , , DOI://10.1016/j.jpdc.2020.04.002 (2020)
Serological Responses to Human Virome Define Clinical Outcomes of Italian Patients Infected with SARS-CoV-2 Wang, L; Candia, J; Ma, L et al. medRxiv, DOI://10.1101/2020.09.04.20187088 (2020)
In silico Drug Repurposing to combat COVID-19 based on Pharmacogenomics of Patient Transcriptomic Data Das, S; Camphausen, K; Shankavaram, U; , Res Sq, DOI://10.21203/rs.3.rs-39128/v1 (2020)
Maternal-fetal genetic interactions, imprinting, and risk of placental abruption Workalemahu, T; Enquobahrie, DA; Gelaye, B et al. J Matern Fetal Neonatal Med, DOI://10.1080/14767058.2020.1822314 (2020)
Subsequent Neoplasm Risk Associated With Rare Variants in DNA Damage Response and Clinical Radiation Sensitivity Syndrome Genes in the Childhood Cancer Survivor Study Morton, LM; Karyadi, DM; Hartley, SW et al. JCO Precis Oncol, DOI://10.1200/PO.20.00141 (2020)

Organ Dose Conversion Coefficients Calculated for Korean Pediatric and Adult Voxel Phantoms Exposed to External Photon Fields Choonsik Lee, Yeon Soo Yeom, Keith Griffin, Choonik Lee, Ae-Kyoung Lee, Hyung-do Choi J. Radiat. Prot. Res, doi://10.14407/jrpr.2020.45.2.69 (2020)
Power of Microbiome Beta-Diversity Analyses Based on Standard Reference Samples Gail, MH; Wan, Y; Shi, J; , Am J Epidemiol, DOI://10.1093/aje/kwaa204 (2020)
The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction Yang, S; Zhang, Y; Ting, CY et al. Dev. Cell, DOI://10.1016/j.devcel.2020.08.006 (2020)
Immune correlates analysis using vaccinees from test negative designs Follmann, DA; Dodd, L; , Biostatistics, DOI://10.1093/biostatistics/kxaa037 (2020)
Atherosclerotic Plaque Burden on Abdominal CT: Automated Assessment With Deep Learning on Noncontrast and Contrast-enhanced Scans Summers, RM; Elton, DC; Lee, S et al. Acad Radiol, DOI://10.1016/j.acra.2020.08.022 (2020)
Untangling the relatedness among correlations, part III: Inter-subject correlation analysis through Bayesian multilevel modeling for naturalistic scanning Chen, G; Taylor, PA; Qu, X et al. Neuroimage, DOI://10.1016/j.neuroimage.2019.116474 (2020)

The role of RHOT1 and RHOT2 genetic variation on Parkinson disease risk and onset Periñán, MT; Gómez-Garre, P; Blauwendraat, C; Mir, P; Bandres-Ciga, S; , ; , Neurobiol Aging, DOI://10.1016/j.neurobiolaging.2020.07.003 (2020)
Formation and Properties of a Self-Assembled Nanoparticle-Supported Lipid Bilayer Probed through Molecular Dynamics Simulations Jing, H; Wang, Y; Desai, PR; Ramamurthi, KS; Das, S; , Langmuir, DOI://10.1021/acs.langmuir.0c00593 (2020)
Functional Dissection of Basal Ganglia Inhibitory Inputs onto Substantia Nigra Dopaminergic Neurons Evans, RC; Twedell, EL; Zhu, M; Ascencio, J; Zhang, R; Khaliq, ZM; , Cell Rep, DOI://10.1016/j.celrep.2020.108156 (2020)
Liver Steatosis Categorization on Contrast-Enhanced CT Using a Fully-Automated Deep Learning Volumetric Segmentation Tool: Evaluation in 1,204 Heathy Adults Using Unenhanced CT as Reference Standard Pickhardt, PJ; Blake, GM; Graffy, PM et al. AJR Am J Roentgenol, DOI://10.2214/AJR.20.24415 (2020)
RUNX1 and CBFβ-SMMHC transactivate target genes together in abnormal myeloid progenitors for leukemia development Zhen, T; Cao, Y; Ren, G et al. Blood, DOI://10.1182/blood.2020007747 (2020)
Ketamine modulates fronto-striatal circuitry in depressed and healthy individuals Mkrtchian, A; Evans, JW; Kraus, C et al. Mol Psychiatry, DOI://10.1038/s41380-020-00878-1 (2020)
Pan-cancer analysis of whole genomes ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium Nature, DOI://10.1038/s41586-020-1969-6 (2020)
[Imaging of Tumor-Specific Hypoxia Dynamics and Its Significance in Radiation Biology] Yasui, H; Matsumoto, S; Inanami, O; Krishna, MC; , Igaku Butsuri, DOI://10.11323/jjmp.40.1_13 (2020)
Structural Features that Distinguish Inactive and Active PI3K Lipid Kinases Zhang, M; Jang, H; Nussinov, R; , J. Mol. Biol., DOI://10.1016/j.jmb.2020.09.002 (2020)
Targeting the PI3K/AKT Pathway Overcomes Enzalutamide Resistance by Inhibiting Induction of the Glucocorticoid Receptor Adelaiye-Ogala, R; Gryder, BE; Nguyen, YTM et al. Mol. Cancer Ther., DOI://10.1158/1535-7163.MCT-19-0936 (2020)
Knockout of the caspase 8 associated protein 2 gene improves recombinant protein expression in HEK293 cells through up-regulation of the cyclin-dependent kinase inhibitor 2A gene Abaandou, L; Sharma, AK; Shiloach, J; , Biotechnol. Bioeng., DOI://10.1002/bit.27561 (2020)
Voriconazole and the Risk of Keratinocyte Carcinomas Among Lung Transplant Recipients in the United States D'Arcy, ME; Pfeiffer, RM; Rivera, DR et al. JAMA Dermatol, DOI://10.1001/jamadermatol.2020.1141 (2020)

Polygenic risk for anxiety influences anxiety comorbidity and suicidal behavior in bipolar disorder Lopes, FL; Zhu, K; Purves, KL et al. Transl Psychiatry, DOI://10.1038/s41398-020-00981-5 (2020)
Contacting domains segregate a lipid transporter from a solute transporter in the malarial host-parasite interface Garten, M; Beck, JR; Roth, R et al. Nat Commun, DOI://10.1038/s41467-020-17506-9 (2020)
Theta-burst TMS to the posterior superior temporal sulcus decreases resting-state fMRI connectivity across the face processing network Handwerker, DA; Ianni, G; Gutierrez, B et al. Netw Neurosci, DOI://10.1162/netn_a_00145 (2020)
A mega-analysis of expression quantitative trait loci in retinal tissue Strunz, T; Kiel, C; Grassmann, F et al. PLoS Genet., DOI://10.1371/journal.pgen.1008934 (2020)
Pharmacologic fibroblast reprogramming into photoreceptors restores vision Mahato, B; Kaya, KD; Fan, Y et al. Nature, DOI://10.1038/s41586-020-2201-4 (2020)
Tracking the adaptation and compensation processes of patients brain arterial network to an evolving glioblastoma Zhu, J; Teolis, S; Biassou, N et al. IEEE Trans Pattern Anal Mach Intell, DOI://10.1109/TPAMI.2020.3008379 (2020)

High throughput assessment of biomarkers in tissue microarrays using artificial intelligence: PTEN loss as a proof-of-principle in multi-center prostate cancer cohorts Harmon, SA; Patel, PG; Sanford, TH et al. Mod. Pathol., DOI://10.1038/s41379-020-00674-w (2020)
Miswired Enhancer Logic Drives a Cancer of the Muscle Lineage Gryder, BE; Wachtel, M; Chang, K et al. iScience, DOI://10.1016/j.isci.2020.101103 (2020)
Robust Accurate Identification and Biomass Estimates of Microorganisms via Tandem Mass Spectrometry Alves, G; Yu, YK; , J. Am. Soc. Mass Spectrom., DOI://10.1021/jasms.9b00035 (2020)
Overexpression of ABCB1 and ABCG2 contributes to reduced efficacy of the PI3K/mTOR inhibitor samotolisib (LY3023414) in cancer cell lines Wu, CP; Hung, CY; Lusvarghi, S et al. Biochem. Pharmacol., DOI://10.1016/j.bcp.2020.114137 (2020)
Automated CT biomarkers for opportunistic prediction of future cardiovascular events and mortality in an asymptomatic screening population: a retrospective cohort study Pickhardt, PJ; Graffy, PM; Zea, R et al. Lancet Digit Health, DOI://10.1016/S2589-7500(20)30025-X (2020)
Lsh/HELLS is required for B lymphocyte development and immunoglobulin class switch recombination He, Y; Ren, J; Xu, X et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.2004112117 (2020)

New Guinea highland wild dogs are the original New Guinea singing dogs Surbakti, S; Parker, HG; McIntyre, JK et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.2007242117 (2020)
G-protein coupled receptor Gpr115 ( Adgrf4) is required for enamel mineralization mediated by ameloblasts Chiba, Y; Yoshizaki, K; Saito, K et al. J. Biol. Chem., DOI://10.1074/jbc.RA120.014281 (2020)
TickSialoFam (TSFam): A Database That Helps to Classify Tick Salivary Proteins, a Review on Tick Salivary Protein Function and Evolution, With Considerations on the Tick Sialome Switching Phenomenon Ribeiro, JMC; Mans, BJ; Front Cell Infect Microbiol, DOI://10.3389/fcimb.2020.00374 (2020)
Bedaquiline inhibits the yeast and human mitochondrial ATP synthases Luo, M; Zhou, W; Patel, H et al. Commun Biol, DOI://10.1038/s42003-020-01173-z (2020)
Power calculation for the general two-sample Mendelian randomization analysis Deng, L; Zhang, H; Yu, K; , Genet Epidemiol, DOI://10.1002/gepi.22284 (2020)
ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis Paiano, J; Wu, W; Yamada, S et al. Nat Commun, DOI://10.1038/s41467-020-14654-w (2020)

Disome and Trisome Profiling Reveal Genome-wide Targets of Ribosome Quality Control Meydan, S; Guydosh, NR; Mol. Cell, DOI://10.1016/j.molcel.2020.06.010 (2020)
A Peptide Derived from Lens Epithelium-Derived Growth Factor Stimulates HIV-1 DNA Integration and Facilitates Intasome Structural Studies Li, M; Chen, X; Wang, H; Jurado, KA; Engelman, AN; Craigie, R; J. Mol. Biol., DOI://10.1016/j.jmb.2020.01.040 (2020)
Pathway identification through transcriptome analysis Terabayashi, T; Germino, GG; Menezes, LF; Cell. Signal., DOI://10.1016/j.cellsig.2020.109701 (2020)
Phenotype stability under dynamic brain-tumor environment stimuli maps glioblastoma progression in patients Rajapakse, VN; Herrada, S; Lavi, O; , Sci Adv, DOI://10.1126/sciadv.aaz4125 (2020)
GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 Infection Hattori, SI; Higshi-Kuwata, N; Raghavaiah, J et al. mBio, DOI://10.1128/mBio.01833-20 (2020)
AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2 Yang, A; Shao, TJ; Bofill-De Ros, X et al. Nat Commun, DOI://10.1038/s41467-020-16533-w (2020)

Protein kinase A inhibitor proteins (PKIs) divert GPCR-Gαs-cAMP signaling toward EPAC and ERK activation and are involved in tumor growth Hoy, JJ; Salinas Parra, N; Park, J; Kuhn, S; Iglesias-Bartolome, R; FASEB J., DOI://10.1096/fj.202001515R (2020)
Whole Blood DNA Methylation Signatures of Diet Are Associated With Cardiovascular Disease Risk Factors and All-Cause Mortality Ma, J; Rebholz, CM; Braun, KVE et al. Circ Genom Precis Med, DOI://10.1161/CIRCGEN.119.002766 (2020)
A Platelet Function Modulator of Thrombin Activation Is Causally Linked to Cardiovascular Disease and Affects PAR4 Receptor Signaling Rodriguez, BAT; Bhan, A; Beswick, A et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2020.06.008 (2020)
Structure and Mechanism of DHHC Protein Acyltransferases Stix, R; Lee, CJ; Faraldo-Gómez, JD; Banerjee, A; J. Mol. Biol., DOI://10.1016/j.jmb.2020.05.023 (2020)
Genome-wide Association Study Identifies HLA-DPB1 as a Significant Risk Factor for Severe Aplastic Anemia Savage, SA; Viard, M; O'hUigin, C et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2020.01.004 (2020)
Retinal pigment epithelium transcriptome analysis in chronic smoking reveals a suppressed innate immune response and activation of differentiation pathways Wang, L; Kaya, KD; Kim, S et al. Free Radic. Biol. Med., DOI://10.1016/j.freeradbiomed.2020.06.004 (2020)

A protocol for preparing explicitly solvated systems for stable molecular dynamics simulations Roe, DR; Brooks, BR; , J Chem Phys, DOI://10.1063/5.0013849 (2020)
Transcription factor AP2 controls cnidarian germ cell induction DuBuc, TQ; Schnitzler, CE; Chrysostomou, E et al. Science, DOI://10.1126/science.aay6782 (2020)
Robotic High-Throughput Biomanufacturing and Functional Differentiation of Human Pluripotent Stem Cells Tristan, CA; Ormanoglu, P; Slamecka, J et al. bioRxiv, DOI://10.1101/2020.08.03.235242 (2020)
DONSON and FANCM associate with different replisomes distinguished by replication timing and chromatin domain Zhang, J; Bellani, MA; James, RC et al. Nat Commun, DOI://10.1038/s41467-020-17449-1 (2020)
HiCanu: accurate assembly of segmental duplications, satellites, and allelic variants from high-fidelity long reads Nurk, S; Walenz, BP; Rhie, A et al. Genome Res., DOI://10.1101/gr.263566.120 (2020)
High Levels of Chromosomal Copy Number Alterations and TP53 Mutations Correlate with Poor Outcome in Younger Breast Cancer Patients Koçak, A; Heselmeyer-Haddad, K; Lischka, A et al. Am. J. Pathol., DOI://10.1016/j.ajpath.2020.04.015 (2020)

Estimating the Heritability of Developmental Change in Neural Connectivity, and Its Association With Changing Symptoms of Attention-Deficit/Hyperactivity Disorder Sudre, G; Bouyssi-Kobar, M; Norman, L; Sharp, W; Choudhury, S; Shaw, P; Biol. Psychiatry, DOI://10.1016/j.biopsych.2020.06.007 (2020)
Diploid genome architecture revealed by multi-omic data of hybrid mice Han, Z; Cui, K; Placek, K et al. Genome Res., DOI://10.1101/gr.257568.119 (2020)
Cryptic genetic variation enhances primate L1 retrotransposon survival by enlarging the functional coiled coil sequence space of ORF1p Furano, AV; Jones, CE; Periwal, V; Callahan, KE; Walser, JC; Cook, PR; PLoS Genet., DOI://10.1371/journal.pgen.1008991 (2020)
Adapting CHMTRN (CHeMistry TRaNslator) for a New Use Judson, PN; Ihlenfeldt, WD; Patel, H; Delann�e, V; Tarasova, N; Nicklaus, MC; , J Chem Inf Model, DOI://10.1021/acs.jcim.0c00448 (2020)
Molecular mechanisms underlying menthol binding and activation of TRPM8 ion channel Xu, L; Han, Y; Chen, X et al. Nat Commun, DOI://10.1038/s41467-020-17582-x (2020)
White matter microstructure in youth with and at risk for bipolar disorder Linke, JO; Stavish, C; Adleman, NE et al. Bipolar Disord, DOI://10.1111/bdi.12885 (2020)

Dose-dependent activation of gene expression is achieved using CRISPR and small molecules that recruit endogenous chromatin machinery Chiarella, AM; Butler, KV; Gryder, BE et al. Nat. Biotechnol., DOI://10.1038/s41587-019-0296-7 (2020)
Licochalcone A Selectively Resensitizes ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Drugs Wu, CP; Lusvarghi, S; Hsiao, SH et al. J. Nat. Prod., DOI://10.1021/acs.jnatprod.9b01022 (2020)
Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome Chen, X; Dorris, Z; Shi, D et al. Structure, DOI://10.1016/j.str.2020.07.011 (2020)
Exploration of Alternative Scaffolds for P2Y 14 Receptor Antagonists Containing a Biaryl Core Jung, YH; Yu, J; Wen, Z et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.0c00745 (2020)
A preliminary study on functional activation and connectivity during frustration in youths with bipolar disorder Ross, AJ; Roule, AL; Deveney, CM et al. Bipolar Disord, DOI://10.1111/bdi.12985 (2020)
Impact of Cysteine Residues on MHC Binding Predictions and Recognition by Tumor-Reactive T Cells Sachs, A; Moore, E; Kosaloglu-Yalcin, Z et al. J. Immunol., DOI://10.4049/jimmunol.1901173 (2020)
Integrative Genomic Analysis Reveals Four Protein Biomarkers for Platelet Traits Lee, DH; Yao, C; Bhan, A et al. Circ. Res., DOI://10.1161/CIRCRESAHA.119.316447 (2020)
Topoisomerase 3β knockout mice show transcriptional and behavioural impairments associated with neurogenesis and synaptic plasticity Joo, Y; Xue, Y; Wang, Y et al. Nat Commun, DOI://10.1038/s41467-020-16884-4 (2020)
Hsd17b13 Deficiency Does not Protect Mice From Obesogenic Diet Injury Ma, Y; Brown, PM; Lin, DD et al. Hepatology, DOI://10.1002/hep.31517 (2020)
Automated Abdominal CT Imaging Biomarkers for Opportunistic Prediction of Future Major Osteoporotic Fractures in Asymptomatic Adults Pickhardt, PJ; Graffy, PM; Zea, R et al. Radiology, DOI://10.1148/radiol.2020200466 (2020)
Opportunistic Screening for Metabolic Syndrome in Asymptomatic Adults Utilizing Fully Automated Abdominal CT-based Biomarkers Pickhardt, PJ; Graffy, PM; Zea, R et al. AJR Am J Roentgenol, DOI://10.2214/AJR.20.23049 (2020)
Transcriptional variation of sensory-related genes in natural populations of Aedes albopictus Gomulski, LM; Manni, M; Carraretto, D et al. BMC Genomics, DOI://10.1186/s12864-020-06956-6 (2020)

Artificial neural networks for the inverse design of nanoparticles with preferential nano-bio behaviors Hassan, SA J Chem Phys, DOI://10.1063/5.0013990 (2020)
Longitudinal changes in resting state networks in early presymptomatic carriers of C9orf72 expansions Shoukry, RS; Waugh, R; Bartlett, D; Raitcheva, D; Floeter, MK; Neuroimage Clin, DOI://10.1016/j.nicl.2020.102354 (2020)
SOS1 interacts with Grb2 through regions that induce closed nSH3 conformations Liao, TJ; Jang, H; Fushman, D; Nussinov, R; J Chem Phys, DOI://10.1063/5.0013926 (2020)
Impaired angiogenesis and extracellular matrix metabolism in autosomal-dominant hyper-IgE syndrome Dmitrieva, NI; Walts, AD; Nguyen, DP et al. J. Clin. Invest., DOI://10.1172/JCI135490 (2020)
Blood DNA methylation sites predict death risk in a longitudinal study of 12, 300 individuals Colicino, E; Marioni, R; Ward-Caviness, C et al. Aging (Albany NY), DOI://10.18632/aging.103408 (2020)
TREML4 Promotes Inflammatory Programs in Human and Murine Macrophages and Alters Atherosclerosis Lesion Composition in the Apolipoprotein E Deficient Mouse Gonzalez-Cotto, M; Guo, L; Karwan, M et al. Front Immunol, DOI://10.3389/fimmu.2020.00397 (2020)
Integrative structural, functional, and transcriptomic analyses of sex-biased brain organization in humans Liu, S; Seidlitz, J; Blumenthal, JD; Clasen, LS; Raznahan, A; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1919091117 (2020)
A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity Sanchez-Soto, M; Verma, RK; Willette, BKA et al. Sci Signal, DOI://10.1126/scisignal.aaw5885 (2020)
Quantitative method for estimating stain density in electron microscopy of conventionally prepared biological specimens Fera, A; He, Q; Zhang, G; Leapman, RD; J Microsc, DOI://10.1111/jmi.12865 (2020)
Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders Seidlitz, J; Nadig, A; Liu, S et al. Nat Commun, DOI://10.1038/s41467-020-17051-5 (2020)
Cutting antiparallel DNA strands in a single active site Chen, X; Cui, Y; Best, RB et al. Nat. Struct. Mol. Biol., DOI://10.1038/s41594-019-0363-2 (2020)
Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets Psaila, B; Wang, G; Rodriguez-Meira, A et al. Mol. Cell, DOI://10.1016/j.molcel.2020.04.008 (2020)

RNA-RNA Interactomes of ProQ and Hfq Reveal Overlapping and Competing Roles Melamed, S; Adams, PP; Zhang, A; Zhang, H; Storz, G; Mol. Cell, DOI://10.1016/j.molcel.2019.10.022 (2020)
HIV-associated gut dysbiosis is independent of sexual practice and correlates with noncommunicable diseases Vujkovic-Cvijin, I; Sortino, O; Verheij, E et al. Nat Commun, DOI://10.1038/s41467-020-16222-8 (2020)
In Silico Drug Design for Purinergic GPCRs: Overview on Molecular Dynamics Applied to Adenosine and P2Y Receptors Salmaso, V; Jacobson, KA; Biomolecules, DOI://10.3390/biom10060812 (2020)
In vitro and in vivo identification of clinically approved drugs that modify ACE2 expression Sinha, S; Cheng, K; Schäffer, AA; Aldape, K; Schiff, E; Ruppin, E; Mol. Syst. Biol., DOI://10.15252/msb.20209628 (2020)
Novel metabolic role for BDNF in pancreatic β-cell insulin secretion Fulgenzi, G; Hong, Z; Tomassoni-Ardori, F et al. Nat Commun, DOI://10.1038/s41467-020-15833-5 (2020)
Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model Cheng, RYS; Patel, NL; Back, T et al. J Vis Exp, DOI://10.3791/60316 (2020)
Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism Gupta, S; Nakabo, S; Blanco, LP et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.2003603117 (2020)
A dose voxel kernel method for rapid reconstruction of out-of-field neutron dose of patients in pencil beam scanning (PBS) proton therapy Yeom, YS; Griffin, KT; Mille, M; Jung, JW; Lee, C; Lee, C; Phys Med Biol, DOI://10.1088/1361-6560/abaa5f (2020)
An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity Debruycker, V; Hutchin, A; Masureel, M et al. Nat. Struct. Mol. Biol., DOI://10.1038/s41594-020-0464-y (2020)
Genotype of CDC73 germline mutation determines risk of parathyroid cancer Li, Y; Zhang, J; Adikaram, PR et al. Endocr. Relat. Cancer, DOI://10.1530/ERC-20-0149 (2020)
EXOSC10 sculpts the transcriptome during the growth-to-maturation transition in mouse oocytes Wu, D; Dean, J; Nucleic Acids Res., DOI://10.1093/nar/gkaa249 (2020)
Different mechanisms for translocation by monomeric and hexameric helicases Gao, Y; Yang, W; Curr. Opin. Struct. Biol., DOI://10.1016/j.sbi.2019.10.003 (2020)

A Viral Exposure Signature Defines Early Onset of Hepatocellular Carcinoma Liu, J; Tang, W; Budhu, A et al. Cell, DOI://10.1016/j.cell.2020.05.038 (2020)
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing Riva, L; Yuan, S; Yin, X et al. Nature, DOI://10.1038/s41586-020-2577-1 (2020)
Laterally Resolved Small-Angle Scattering Intensity from Lipid Bilayer Simulations: An Exact and a Limited-Range Treatment Dorrell, MW; Heberle, FA; Katsaras, J; Maibaum, L; Lyman, E; Sodt, AJ; J Chem Theory Comput, DOI://10.1021/acs.jctc.0c00132 (2020)
Activation and inhibition of nonsense-mediated mRNA decay control the abundance of alternative polyadenylation products Kishor, A; Fritz, SE; Haque, N et al. Nucleic Acids Res., DOI://10.1093/nar/gkaa491 (2020)
Trehalose as an alternative to glycerol as a glassing agent for in vivo DNP MRI Brender, JR; Kishimoto, S; Eaton, GR et al. Magn Reson Med, DOI://10.1002/mrm.28405 (2020)
Molecular mechanisms underlying milk production and viviparity in the cockroach, Diploptera punctata Jennings, EC; Korthauer, MW; Hendershot, JM et al. Insect Biochem. Mol. Biol., DOI://10.1016/j.ibmb.2020.103333 (2020)
Broad immune activation underlies shared set point signatures for vaccine responsiveness in healthy individuals and disease activity in patients with lupus Kotliarov, Y; Sparks, R; Martins, AJ et al. Nat. Med., DOI://10.1038/s41591-020-0769-8 (2020)
Positioning Heterochromatin at the Nuclear Periphery Suppresses Histone Turnover to Promote Epigenetic Inheritance Holla, S; Dhakshnamoorthy, J; Folco, HD et al. Cell, DOI://10.1016/j.cell.2019.12.004 (2020)
Automated glioma grading on conventional MRI images using deep convolutional neural networks Zhuge, Y; Ning, H; Mathen, P et al. Med Phys, DOI://10.1002/mp.14168 (2020)
Penetrance of Parkinson's Disease in LRRK2 p.G2019S Carriers Is Modified by a Polygenic Risk Score Iwaki, H; Blauwendraat, C; Makarious, MB et al. Mov. Disord., DOI://10.1002/mds.27974 (2020)
Resource: A multi-species multi-timepoint transcriptome database and webpage for the pineal gland and retina Chang, E; Fu, C; Coon, SL et al. J. Pineal Res., DOI://10.1111/jpi.12673 (2020)
Targeted therapy guided by single-cell transcriptomic analysis in drug-induced hypersensitivity syndrome: a case report Kim, D; Kobayashi, T; Voisin, B et al. Nat. Med., DOI://10.1038/s41591-019-0733-7 (2020)

Nanopore sequencing and the Shasta toolkit enable efficient de novo assembly of eleven human genomes Shafin, K; Pesout, T; Lorig-Roach, R et al. Nat. Biotechnol., DOI://10.1038/s41587-020-0503-6 (2020)
An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis Xiang, G; Keller, CA; Heuston, E et al. Genome Res., DOI://10.1101/gr.255760.119 (2020)
PLD2-PI(4,5)P2 interactions in fluid phase membranes: Structural modeling and molecular dynamics simulations Han, K; Pastor, RW; Fenollar-Ferrer, C; PLoS ONE, DOI://10.1371/journal.pone.0236201 (2020)
Age Differences in the Neural Correlates of Anxiety Disorders: An fMRI Study of Response to Learned Threat Gold, AL; Abend, R; Britton, JC et al. Am J Psychiatry, DOI://10.1176/appi.ajp.2019.19060650 (2020)
Differential Expression of the Transcription Factor GATA3 Specifies Lineage and Functions of Innate Lymphoid Cells Zhong, C; Zheng, M; Cui, K et al. Immunity, DOI://10.1016/j.immuni.2019.12.001 (2020)
MEIS1 down-regulation by MYC mediates prostate cancer development through elevated HOXB13 expression and AR activity Whitlock, NC; Trostel, SY; Wilkinson, S et al. Oncogene, DOI://10.1038/s41388-020-01389-7 (2020)
Maternal cardiometabolic factors and genetic ancestry influence epigenetic aging of the placenta Workalemahu, T; Shrestha, D; Tajuddin, SM; Tekola-Ayele, F; J Dev Orig Health Dis, DOI://10.1017/S2040174419000801 (2020)
Identification of conserved evolutionary trajectories in tumors Hodzic, E; Shrestha, R; Malikic, S et al. Bioinformatics, DOI://10.1093/bioinformatics/btaa453 (2020)
Drugs Targeting Tumor-Initiating Cells Prolong Survival in a Post-Surgery, Post-Chemotherapy Ovarian Cancer Relapse Model Harrington, BS; Ozaki, MK; Caminear, MW et al. Cancers (Basel), DOI://10.3390/cancers12061645 (2020)
PhISCS-BnB: a fast branch and bound algorithm for the perfect tumor phylogeny reconstruction problem Sadeqi Azer, E; Rashidi Mehrabadi, F; Malikić, S et al. Bioinformatics, DOI://10.1093/bioinformatics/btaa464 (2020)
Early pregnancy dyslipidemia is associated with placental DNA methylation at loci relevant for cardiometabolic diseases Ouidir, M; Zeng, X; Workalemahu, T et al. Epigenomics, DOI://10.2217/epi-2019-0293 (2020)
The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter Plenge, P; Abramyan, AM; Sørensen, G et al. Nat Commun, DOI://10.1038/s41467-020-15292-y (2020)

Epigenome-wide association study of DNA methylation and microRNA expression highlights novel pathways for human complex traits Huan, T; Mendelson, M; Joehanes, R et al. Epigenetics, DOI://10.1080/15592294.2019.1640547 (2020)
Integrated analysis of sialotranscriptome and sialoproteome of the brown dog tick Rhipicephalus sanguineus (s.l.): Insights into gene expression during blood feeding Tirloni, L; Lu, S; Calvo, E et al. J Proteomics, DOI://10.1016/j.jprot.2020.103899 (2020)
Structural basis of seamless excision and specific targeting by piggyBac transposase Chen, Q; Luo, W; Veach, RA; Hickman, AB; Wilson, MH; Dyda, F; Nat Commun, DOI://10.1038/s41467-020-17128-1 (2020)
Telomere-to-telomere assembly of a complete human X chromosome Miga, KH; Koren, S; Rhie, A et al. Nature, DOI://10.1038/s41586-020-2547-7 (2020)
Chromatin remodeler Ino80C acts independently of H2A.Z to evict promoter nucleosomes and stimulate transcription of highly expressed genes in yeast Qiu, H; Biernat, E; Govind, CK et al. Nucleic Acids Res., DOI://10.1093/nar/gkaa571 (2020)
Human Herpesvirus 6 Detection in Alzheimer's Disease Cases and Controls across Multiple Cohorts Allnutt, MA; Johnson, K; Bennett, DA et al. Neuron, DOI://10.1016/j.neuron.2019.12.031 (2020)
Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus Goel, RR; Wang, X; O'Neil, LJ et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1916897117 (2020)
Genome-wide admixture mapping of DSM-IV alcohol dependence, criterion count, and the self-rating of the effects of ethanol in African American populations Lai, D; Kapoor, M; Wetherill, L et al. Am. J. Med. Genet. B Neuropsychiatr. Genet., DOI://10.1002/ajmg.b.32805 (2020)
Concentrations of persistent organic pollutants in maternal plasma and epigenome-wide placental DNA methylation Ouidir, M; Mendola, P; Buck Louis, GM; Kannan, K; Zhang, C; Tekola-Ayele, F; Clin Epigenetics, DOI://10.1186/s13148-020-00894-6 (2020)
Structural insight into mitochondrial β-barrel outer membrane protein biogenesis Diederichs, KA; Ni, X; Rollauer, SE et al. Nat Commun, DOI://10.1038/s41467-020-17144-1 (2020)
Epigenetic Regulation of DNA Repair Pathway Choice by MacroH2A1 Splice Variants Ensures Genome Stability Sebastian, R; Hosogane, EK; Sun, EG et al. Mol. Cell, DOI://10.1016/j.molcel.2020.06.028 (2020)
XAF1 as a modifier of p53 function and cancer susceptibility Pinto, EM; Figueiredo, BC; Chen, W et al. Sci Adv, DOI://10.1126/sciadv.aba3231 (2020)

Evaluation of the Anti-Tumor Activity of the Humanized Monoclonal Antibody NEO-201 in Preclinical Models of Ovarian Cancer Zeligs, KP; Morelli, MP; David, JM et al. Front Oncol, DOI://10.3389/fonc.2020.00805 (2020)
Genome-wide association study data reveal genetic susceptibility to chronic inflammatory intestinal diseases and pancreatic ductal adenocarcinoma risk Yuan, F; Hung, RJ; Walsh, N et al. Cancer Res., DOI://10.1158/0008-5472.CAN-20-0447 (2020)
Soy protein nanofiber scaffolds for uniform maturation of hiPSC-derived retinal pigment epithelium Phelan, MA; Kruczek, K; Wilson, JP et al. Tissue Eng Part C Methods, DOI://10.1089/ten.TEC.2020.0072 (2020)
Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury Wilflingseder, J; Willi, M; Lee, HK et al. Nat Commun, DOI://10.1038/s41467-020-17205-5 (2020)
Deficiency of Adenosine Deaminase 2 (DADA2): Hidden Variants, Reduced Penetrance, and Unusual Inheritance Schnappauf, O; Zhou, Q; Moura, NS et al. J. Clin. Immunol., DOI://10.1007/s10875-020-00817-3 (2020)
Comparison of Oral Microbiota Collected Using Multiple Methods and Recommendations for New Epidemiologic Studies Yano, Y; Hua, X; Wan, Y et al. mSystems, DOI://10.1128/mSystems.00156-20 (2020)

Update of the CHARMM36 United Atom Chain Model for Hydrocarbons and Phospholipids Yu, Y; Klauda, JB; J Phys Chem B, DOI://10.1021/acs.jpcb.0c04795 (2020)
The Intriguing Effects of Substituents in the N-Phenethyl Moiety of Norhydromorphone: A Bifunctional Opioid from a Set of 'Tail Wags Dog' Experiments Wang, M; Irvin, TC; Herdman, CA et al. Molecules, DOI://10.3390/molecules25112640 (2020)
FIGLA, LHX8 and SOHLH1 transcription factor networks regulate mouse oocyte growth and differentiation Wang, Z; Liu, CY; Zhao, Y; Dean, J; Nucleic Acids Res., DOI://10.1093/nar/gkaa101 (2020)
Structure of E3 ligase E6AP with a proteasome-binding site provided by substrate receptor hRpn10 Buel, GR; Chen, X; Chari, R et al. Nat Commun, DOI://10.1038/s41467-020-15073-7 (2020)
Single atom changes in newly synthesized HIV protease inhibitors reveal structural basis for extreme affinity, high genetic barrier, and adaptation to the HIV protease plasticity Bulut, H; Hattori, SI; Aoki-Ogata, H et al. Sci Rep, DOI://10.1038/s41598-020-65993-z (2020)
Single-cell ATAC-Seq in human pancreatic islets and deep learning upscaling of rare cells reveals cell-specific type 2 diabetes regulatory signatures Rai, V; Quang, DX; Erdos, MR et al. Mol Metab, DOI://10.1016/j.molmet.2019.12.006 (2020)
Group testing in mediation analysis Derkach, A; Moore, SC; Boca, SM; Sampson, JN; , Stat Med, DOI://10.1002/sim.8546 (2020)
Inhibition stabilization is a widespread property of cortical networks Sanzeni, A; Akitake, B; Goldbach, HC; Leedy, CE; Brunel, N; Histed, MH; Elife, DOI://10.7554/eLife.54875 (2020)
Large-scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease Bandres-Ciga, S; Saez-Atienzar, S; Kim, JJ et al. Acta Neuropathol., DOI://10.1007/s00401-020-02181-3 (2020)
Sample-weighted semiparametric estimation of cause-specific cumulative risk and incidence using left- or interval-censored data from electronic health records Hyun, N; Katki, HA; Graubard, BI; Stat Med, DOI://10.1002/sim.8544 (2020)
A New Molecular-Mechanics Model for Simulations of Hydrogen Fluoride in Chemistry and Biology Orabi, EA; Faraldo-Gomez, JD; J Chem Theory Comput, DOI://10.1021/acs.jctc.0c00247 (2020)
Single-Cell-Derived Primary Rectal Carcinoma Cell Lines Reflect Intratumor Heterogeneity Associated with Treatment Response Braun, R; Anthuber, L; Hirsch, D et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-19-1984 (2020)

Cotranslational folding cooperativity of contiguous domains of α-spectrin Kemp, G; Nilsson, OB; Tian, P; Best, RB; von Heijne, G; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1909683117 (2020)
Analysis of Thyroid Hormone Receptor α-Knockout Tadpoles Reveals That the Activation of Cell Cycle Program Is Involved in Thyroid Hormone-Induced Larval Epithelial Cell Death and Adult Intestinal Stem Cell Development During Xenopus tropicalis Metamorphosis Tanizaki, Y; Shibata, Y; Zhang, H; Shi, YB; Thyroid, DOI://10.1089/thy.2020.0022 (2020)
Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases de Jesus, AA; Hou, Y; Brooks, S et al. J. Clin. Invest., DOI://10.1172/JCI129301 (2020)
Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery Guardia, CM; Tan, XF; Lian, T et al. Cell Rep, DOI://10.1016/j.celrep.2020.107837 (2020)
Mutations in FYCO1 identified in families with congenital cataracts Iqbal, H; Khan, SY; Zhou, L et al. Mol. Vis., 1090-0535 (2020)
Ancient familial Mediterranean fever mutations in human pyrin and resistance to Yersinia pestis Park, YH; Remmers, EF; Lee, W et al. Nat. Immunol., DOI://10.1038/s41590-020-0705-6 (2020)

Metabolic reprogramming associated with aggressiveness occurs in the G-CIMP-high molecular subtypes of IDH1mut lower grade gliomas Ruiz-Rodado, V; Malta, TM; Seki, T et al. Neuro-oncology, DOI://10.1093/neuonc/noz207 (2020)
Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer Lin, Y; Nakatochi, M; Hosono, Y et al. Nat Commun, DOI://10.1038/s41467-020-16711-w (2020)
The genomic and epigenomic evolutionary history of papillary renal cell carcinomas Zhu, B; Poeta, ML; Costantini, M et al. Nat Commun, DOI://10.1038/s41467-020-16546-5 (2020)
Oral microbial community composition is associated with pancreatic cancer: A case-control study in Iran Vogtmann, E; Han, Y; Caporaso, JG et al. Cancer Med, DOI://10.1002/cam4.2660 (2020)
True S-cones are concentrated in the ventral mouse retina and wired for color detection in the upper visual field Nadal-Nicolás, FM; Kunze, VP; Ball, JM et al. Elife, DOI://10.7554/eLife.56840 (2020)
The RNA-binding protein PTBP1 promotes ATPase-dependent dissociation of the RNA helicase UPF1 to protect transcripts from nonsense-mediated mRNA decay Fritz, SE; Ranganathan, S; Wang, CD; Hogg, JR; J. Biol. Chem., DOI://10.1074/jbc.RA120.013824 (2020)

Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization So, JY; Skrypek, N; Yang, HH et al. Cancer Res., DOI://10.1158/0008-5472.CAN-19-3339 (2020)
fs(1)A1304 1 Is a 5' UTR Deletion of the Essential Gene small ovary in Drosophila Hammond, M; Gomez, JG; Oliver, B; Kucera, S; Benner, L; MicroPubl Biol, DOI://10.17912/micropub.biology.000246 (2020)
Activity-dependent tuning of intrinsic excitability in mouse and human neurogliaform cells Chittajallu, R; Auville, K; Mahadevan, V et al. Elife, DOI://10.7554/eLife.57571 (2020)
eIF1 discriminates against suboptimal initiation sites to prevent excessive uORF translation genome-wide Zhou, F; Zhang, H; Kulkarni, SD; Lorsch, JR; Hinnebusch, AG; RNA, DOI://10.1261/rna.073536.119 (2020)
An improved pig reference genome sequence to enable pig genetics and genomics research Warr, A; Affara, N; Aken, B et al. Gigascience, DOI://10.1093/gigascience/giaa051 (2020)
Integrated VASO and perfusion contrast: A new tool for laminar functional MRI Chai, Y; Li, L; Huber, L; Poser, BA; Bandettini, PA; Neuroimage, DOI://10.1016/j.neuroimage.2019.116358 (2020)

KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage Wolf, G; de Iaco, A; Sun, MA et al. Elife, DOI://10.7554/eLife.56337 (2020)
Beware (Surprisingly Common) Left-Right Flips in Your MRI Data: An Efficient and Robust Method to Check MRI Dataset Consistency Using AFNI Glen, DR; Taylor, PA; Buchsbaum, BR; Cox, RW; Reynolds, RC; Front Neuroinform, DOI://10.3389/fninf.2020.00018 (2020)
Cell-Specific Transcriptional Responses to Heat Shock in the Mouse Utricle Epithelium Sadler, E; Ryals, MM; May, LA et al. Front Cell Neurosci, DOI://10.3389/fncel.2020.00123 (2020)
Tensor image enhancement and optimal multichannel receiver combination analyses for human hyperpolarized 13 C MRSI Chen, HY; Autry, AW; Brender, JR et al. Magn Reson Med, DOI://10.1002/mrm.28328 (2020)
Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies Gurusamy, D; Henning, AN; Yamamoto, TN et al. Cancer Cell, DOI://10.1016/j.ccell.2020.05.004 (2020)
The genomic landscape of metastasis in treatment-naïve breast cancer models Ross, C; Szczepanek, K; Lee, M et al. PLoS Genet., DOI://10.1371/journal.pgen.1008743 (2020)

An imputation approach for fitting two-part mixed effects models for longitudinal semi-continuous data Choo-Wosoba, H; Kundu, D; Albert, PS; Stat Methods Med Res, DOI://10.1177/0962280220927720 (2020)
Variability in the analysis of a single neuroimaging dataset by many teams Botvinik-Nezer, R; Holzmeister, F; Camerer, CF et al. Nature, DOI://10.1038/s41586-020-2314-9 (2020)
Common genetic susceptibility loci link PFAPA syndrome, Behçet's disease, and recurrent aphthous stomatitis Manthiram, K; Preite, S; Dedeoglu, F et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.2002051117 (2020)
Metastasis-specific gene expression in autochthonous and allograft mouse mammary tumor models: stratification and identification of targetable signatures Ross, C; Szczepanek, K; Lee, M et al. Mol. Cancer Res., DOI://10.1158/1541-7786.MCR-20-0046 (2020)
Layer-dependent functional connectivity methods Huber, L; Finn, ES; Chai, Y et al. Prog. Neurobiol., DOI://10.1016/j.pneurobio.2020.101835 (2020)
Dynamic morphogenesis of a pioneer axon in Drosophila and its regulation by Abl tyrosine kinase Clarke, A; McQueen, PG; Fang, HY et al. Mol. Biol. Cell, DOI://10.1091/mbc.E19-10-0563 (2020)
The structure of emotional support networks in families affected by Lynch syndrome Marcum, CS; Lea, D; Eliezer, D; Hadley, DW; Koehly, LM Network Science, doi:10.1017/nws.2020.13 (2020)
Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer Roper, N; Brown, AL; Wei, JS et al. Cell Rep Med, DOI://10.1016/j.xcrm.2020.100007 (2020)
Ensuring meiotic DNA break formation in the mouse pseudoautosomal region Acquaviva, L; Boekhout, M; Karasu, ME et al. Nature, DOI://10.1038/s41586-020-2327-4 (2020)
The undiagnosed diseases program: Approach to diagnosis Macnamara, EF; D'Souza, P; , ; Tifft, CJ; , Transl Sci Rare Dis, DOI://10.3233/TRD-190045 (2020)
DNA methylation loci in placenta associated with birthweight and expression of genes relevant for early development and adult diseases Tekola-Ayele, F; Zeng, X; Ouidir, M et al. Clin Epigenetics, DOI://10.1186/s13148-020-00873-x (2020)
Atomistic mechanism of transmembrane helix association Domański, J; Sansom, MSP; Stansfeld, PJ; Best, RB; PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1007919 (2020)
Peptidylarginine Deiminase IV Regulates Breast Cancer Stem Cells via a Novel Tumor Cell-Autonomous Suppressor Role Moshkovich, N; Ochoa, HJ; Tang, B et al. Cancer Res., DOI://10.1158/0008-5472.CAN-19-3018 (2020)
Discovery, Optimization, and Characterization of ML417: A Novel and Highly Selective D 3 Dopamine Receptor Agonist Moritz, AE; Free, RB; Weiner, WS et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.0c00424 (2020)
Multiresolution Application of Artificial Intelligence in Digital Pathology for Prediction of Positive Lymph Nodes From Primary Tumors in Bladder Cancer Harmon, SA; Sanford, TH; Brown, GT et al. JCO Clin Cancer Inform, DOI://10.1200/CCI.19.00155 (2020)
Dynorphin and Enkephalin Opioid Peptides and Transcripts in Spinal Cord and Dorsal Root Ganglion During Peripheral Inflammatory Hyperalgesia and Allodynia Sapio, MR; Iadarola, MJ; Loydpierson, AJ et al. J Pain, DOI://10.1016/j.jpain.2020.01.001 (2020)
Predicting RNA SHAPE scores with deep learning Bliss, N; Bindewald, E; Shapiro, BA; RNA Biol, DOI://10.1080/15476286.2020.1760534 (2020)
The Heterogeneity of Anxious Phenotypes: Neural Responses to Errors in Treatment-Seeking Anxious and Behaviorally Inhibited Youths Smith, AR; White, LK; Leibenluft, E et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2019.05.014 (2020)
Infant behavioral reactivity predicts change in amygdala volume 12 years later Filippi, CA; Sachs, JF; Phillips, D et al. Dev Cogn Neurosci, DOI://10.1016/j.dcn.2020.100776 (2020)
ORCA/LRWD1 Regulates Homologous Recombination at ALT-Telomeres by Modulating Heterochromatin Organization Hsu, RYC; Lin, YC; Redon, C et al. iScience, DOI://10.1016/j.isci.2020.101038 (2020)
Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker Menon, R; Otto, EA; Hoover, P et al. JCI Insight, DOI://10.1172/jci.insight.133267 (2020)
Trans-ethnic meta-analysis of genome-wide association studies identifies maternal ITPR1 as a novel locus influencing fetal growth during sensitive periods in pregnancy Tekola-Ayele, F; Zhang, C; Wu, J et al. PLoS Genet., DOI://10.1371/journal.pgen.1008747 (2020)
Synthesis and evaluation of the anti-hepatitis B virus activity of 4'-Azido-thymidine analogs and 4'-Azido-2'-deoxy-5-methylcytidine analogs: structural insights for the development of a novel anti-HBV agent Onitsuka, K; Tokuda, R; Kuwata-Higashi, N et al. Nucleosides Nucleotides Nucleic Acids, DOI://10.1080/15257770.2019.1664749 (2020)
Plasmodium vivax and Human Hexokinases Share Similar Active Sites but Display Distinct Quaternary Architectures Srivastava, SS; Darling, JE; Suryadi, J; Morris, JC; Drew, ME; Subramaniam, S; IUCrJ, DOI://10.1107/S2052252520002456 (2020)

Genetic and epigenetic intratumor heterogeneity impacts prognosis of lung adenocarcinoma Hua, X; Zhao, W; Pesatori, AC et al. Nat Commun, DOI://10.1038/s41467-020-16295-5 (2020)
Dual histone methyl reader ZCWPW1 facilitates repair of meiotic double strand breaks in male mice Mahgoub, M; Paiano, J; Bruno, M et al. Elife, DOI://10.7554/eLife.53360 (2020)
Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase Palmieri, EM; Gonzalez-Cotto, M; Baseler, WA et al. Nat Commun, DOI://10.1038/s41467-020-14433-7 (2020)
Fast detection and reduction of local transient artifacts in resting-state fMRI Jo, HJ; Reynolds, RC; Gotts, SJ et al. Comput. Biol. Med., DOI://10.1016/j.compbiomed.2020.103742 (2020)
Accelerated epigenetic age and cognitive decline among urban-dwelling adults Beydoun, MA; Shaked, D; Tajuddin, SM; Weiss, J; Evans, MK; Zonderman, AB; Neurology, DOI://10.1212/WNL.0000000000008756 (2020)
Conserved protein Pir2 ARS2 mediates gene repression through cryptic introns in lncRNAs. Thillainadesan, G; Xiao, H; Holla, S et al. Nat Commun, DOI://10.1038/s41467-020-16280-y (2020)

Patients infected with Mycobacterium africanum versus Mycobacterium tuberculosis possess distinct intestinal microbiota Namasivayam, S; Diarra, B; Diabate, S et al. PLoS Negl Trop Dis, DOI://10.1371/journal.pntd.0008230 (2020)
Assessment of Genetic Association Between Parkinson Disease and Bipolar Disorder Bandres-Ciga, S; Blauwendraat, C; Singleton, AB; JAMA Neurol, DOI://10.1001/jamaneurol.2020.0248 (2020)
Dissecting the phenotypic and functional heterogeneity of mouse inflammatory osteoclasts by the expression of Cx3cr1 Madel, MB; Ibáñez, L; Ciucci, T et al. Elife, DOI://10.7554/eLife.54493 (2020)
Characterization of the development of the mouse cochlear epithelium at the single cell level Kolla, L; Kelly, MC; Mann, ZF et al. Nat Commun, DOI://10.1038/s41467-020-16113-y (2020)
Whole exome sequencing in patients with Williams-Beuren syndrome followed by disease modeling in mice points to four novel pathways that may modify stenosis risk Parrish, PCR; Liu, D; Knutsen, RH et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddaa093 (2020)
Medin Oligomer Membrane Pore Formation: A Potential Mechanism of Vascular Dysfunction Younger, S; Jang, H; Davies, HA et al. Biophys. J., DOI://10.1016/j.bpj.2020.04.026 (2020)

Assessing established BMI variants for a role in nighttime eating behavior in robustly phenotyped Southwestern American Indians Köroğlu, Ç; Gluck, ME; Traurig, M et al. Eur J Clin Nutr, DOI://10.1038/s41430-020-0654-z (2020)
Distinct gene expression patterns in vector-residing Leishmania infantum identify parasite stage-enriched markers Coutinho-Abreu, IV; Serafim, TD; Meneses, C; Kamhawi, S; Oliveira, F; Valenzuela, JG; PLoS Negl Trop Dis, DOI://10.1371/journal.pntd.0008014 (2020)
Somatic SMAD3-activating mutations cause melorheostosis by up-regulating the TGF-β/SMAD pathway Kang, H; Jha, S; Ivovic, A et al. J. Exp. Med., DOI://10.1084/jem.20191499 (2020)
Genome-wide association studies of the self-rating of effects of ethanol (SRE) Lai, D; Wetherill, L; Kapoor, M et al. Addict Biol, DOI://10.1111/adb.12800 (2020)
Dimensionality, information and learning in prefrontal cortex Bartolo, R; Saunders, RC; Mitz, AR; Averbeck, BB; PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1007514 (2020)
Ductal Carcinoma In Situ Progression in Dog Model of Breast Cancer Mohammed, SI; Utturkar, S; Lee, M et al. Cancers (Basel), DOI://10.3390/cancers12020418 (2020)

Amelotin is expressed in retinal pigment epithelium and localizes to hydroxyapatite deposits in dry age-related macular degeneration Rajapakse, D; Peterson, K; Mishra, S et al. Transl Res, DOI://10.1016/j.trsl.2020.02.007 (2020)
Creating 2D Occupancy Plots Using plot2DO Beati, P; Chereji, RV; Methods Mol. Biol., DOI://10.1007/978-1-0716-0301-7_5 (2020)
Haplotype-resolved genomes provide insights into structural variation and gene content in Angus and Brahman cattle Low, WY; Tearle, R; Liu, R et al. Nat Commun, DOI://10.1038/s41467-020-15848-y (2020)
Quantitative Proteomics of All 14 Renal Tubule Segments in Rat Limbutara, K; Chou, CL; Knepper, MA; J. Am. Soc. Nephrol., DOI://10.1681/ASN.2020010071 (2020)
Id1 and Id3 Maintain Steady-State Hematopoiesis by Promoting Sinusoidal Endothelial Cell Survival and Regeneration Gadomski, S; Singh, SK; Singh, S et al. Cell Rep, DOI://10.1016/j.celrep.2020.107572 (2020)
Genetic model of MS severity predicts future accumulation of disability Jackson, KC; Sun, K; Barbour, C et al. Ann. Hum. Genet., DOI://10.1111/ahg.12342 (2020)
Stress keratin 17 enhances papillomavirus infection-induced disease by downregulating T cell recruitment Wang, W; Uberoi, A; Spurgeon, M et al. PLoS Pathog., DOI://10.1371/journal.ppat.1008206 (2020)
Survey of ribose ring pucker of signaling nucleosides and nucleotides Salmaso, V; Jacobson, KA; Nucleosides Nucleotides Nucleic Acids, DOI://10.1080/15257770.2019.1658115 (2020)
Histone Deacetylases in Kidney Physiology and Acute Kidney Injury Hyndman, KA Semin. Nephrol., DOI://10.1016/j.semnephrol.2020.01.005 (2020)
The interdependence of mammary-specific super-enhancers and their native promoters facilitates gene activation during pregnancy Zeng, X; Lee, HK; Wang, C; Achikeh, P; Liu, C; Hennighausen, L; Exp. Mol. Med., DOI://10.1038/s12276-020-0425-x (2020)
Truncated (N)-Methanocarba Nucleosides as Partial Agonists at Mouse and Human A 3 Adenosine Receptors: Affinity Enhancement by N6-(2-Phenylethyl) Substitution Tosh, DK; Salmaso, V; Rao, H et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.0c00235 (2020)
Expression of the muscle-associated gene MYF6 in hairy cell leukemia Arons, E; Zhou, H; Sokolsky, M et al. PLoS ONE, DOI://10.1371/journal.pone.0227586 (2020)

Genome-wide Profiling Identifies DNA Methylation Signatures of Aging in Rod Photoreceptors Associated with Alterations in Energy Metabolism Corso-Díaz, X; Gentry, J; Rebernick, R et al. Cell Rep, DOI://10.1016/j.celrep.2020.107525 (2020)
Protonation state of the selectivity filter of bacterial voltage-gated sodium channels is modulated by ions Damjanovic, A; Chen, AY; Rosenberg, RL; Roe, DR; Wu, X; Brooks, BR; , Proteins, DOI://10.1002/prot.25831 (2020)
Sperm Head-Tail Linkage Requires Restriction of Pericentriolar Material to the Proximal Centriole End Galletta, BJ; Ortega, JM; Smith, SL et al. Dev. Cell, DOI://10.1016/j.devcel.2020.02.006 (2020)
Prefrontal Cortex Predicts State Switches during Reversal Learning Bartolo, R; Averbeck, BB; Neuron, DOI://10.1016/j.neuron.2020.03.024 (2020)
Phase-plate cryo-EM structure of the Widom 601 CENP-A nucleosome core particle reveals differential flexibility of the DNA ends Boopathi, R; Danev, R; Khoshouei, M et al. Nucleic Acids Res., DOI://10.1093/nar/gkaa246 (2020)
How mouse RAG recombinase avoids DNA transposition Chen, X; Cui, Y; Wang, H; Zhou, ZH; Gellert, M; Yang, W; Nat. Struct. Mol. Biol., DOI://10.1038/s41594-019-0366-z (2020)

Intrinsic connections between thalamic sub-regions and the lateral prefrontal cortex are differentially impacted by acute methylphenidate Gorka, AX; Lago, TR; Balderston, N et al. Psychopharmacology (Berl.), DOI://10.1007/s00213-020-05505-z (2020)
7-Deaza-7-fluoro modification confers on 4'-cyano-nucleosides potent activity against entecavir/adefovir-resistant HBV variants and favorable safety Hayashi, S; Higashi-Kuwata, N; Das, D et al. Antiviral Res., DOI://10.1016/j.antiviral.2020.104744 (2020)
Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas Hickman, AB; Kailasan, S; Genzor, P; Haase, AD; Dyda, F; Elife, DOI://10.7554/eLife.50004 (2020)
AGO2 Mediates MYC mRNA Stability in Hepatocellular Carcinoma Zhang, K; Pomyen, Y; Barry, AE et al. Mol. Cancer Res., DOI://10.1158/1541-7786.MCR-19-0805 (2020)
Systematic integration of GATA transcription factors and epigenomes via IDEAS paints the regulatory landscape of hematopoietic cells Hardison, RC; Zhang, Y; Keller, CA et al. IUBMB Life, DOI://10.1002/iub.2195 (2020)
Confidence intervals for the difference between two relative risks Sampson, JN; Gail, MH; Stat Methods Med Res, DOI://10.1177/0962280220915737 (2020)

High density of unrepaired genomic ribonucleotides leads to Topoisomerase 1-mediated severe growth defects in absence of ribonucleotide reductase Cerritelli, SM; Iranzo, J; Sharma, S et al. Nucleic Acids Res., DOI://10.1093/nar/gkaa103 (2020)
Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression Farmer, CA; Gilbert, JR; Moaddel, R et al. Neuropsychopharmacology, DOI://10.1038/s41386-020-0663-6 (2020)
Erasure machine: Inverse Ising inference from reweighting of observation frequencies Jo, J; Hoang, DT; Periwal, V; , Phys Rev E, DOI://10.1103/PhysRevE.101.032107 (2020)
Skin Microbiota Perturbations Are Distinct and Disease Severity-Dependent in Hidradenitis Suppurativa Naik, HB; Jo, JH; Paul, M; Kong, HH; , J. Invest. Dermatol., DOI://10.1016/j.jid.2019.08.445 (2020)
Investigation of the Influence of Thyroid Location on Iodine-131 S Values Yeom, YS; Villoing, D; Greenstein, N et al. Radiat Prot Dosimetry, DOI://10.1093/rpd/ncaa027 (2020)
A Probabilistic Classification Tool for Genetic Subtypes of Diffuse Large B Cell Lymphoma with Therapeutic Implications Wright, GW; Huang, DW; Phelan, JD et al. Cancer Cell, DOI://10.1016/j.ccell.2020.03.015 (2020)

In vivo functional analysis of non-conserved human lncRNAs associated with cardiometabolic traits Ruan, X; Li, P; Chen, Y et al. Nat Commun, DOI://10.1038/s41467-019-13688-z (2020)
A hidden Markov modeling approach for identifying tumor subclones in next-generation sequencing studies Choo-Wosoba, H; Albert, PS; Zhu, B; Biostatistics, DOI://10.1093/biostatistics/kxaa013 (2020)
Quantum chemical predictions of water-octanol partition coefficients applied to the SAMPL6 logP blind challenge Jones, MR; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-020-00286-1 (2020)
Multi-phase Boltzmann weighting: accounting for local inhomogeneity in molecular simulations of water-octanol partition coefficients in the SAMPL6 challenge Krämer, A; Hudson, PS; Jones, MR; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-020-00285-2 (2020)
Feedback inhibition and its control in an insect olfactory circuit Ray, S; Aldworth, ZN; Stopfer, MA; Elife, DOI://10.7554/eLife.53281 (2020)
Interpretation of HDX Data by Maximum-Entropy Reweighting of Simulated Structural Ensembles Bradshaw, RT; Marinelli, F; Faraldo-Gómez, JD; Forrest, LR; Biophys. J., DOI://10.1016/j.bpj.2020.02.005 (2020)

A Shared Regulatory Element Controls the Initiation of Tcf7 Expression During Early T Cell and Innate Lymphoid Cell Developments Harly, C; Kenney, D; Wang, Y et al. Front Immunol, DOI://10.3389/fimmu.2020.00470 (2020)
Idiosynchrony: From shared responses to individual differences during naturalistic neuroimaging Finn, ES; Glerean, E; Khojandi, AY et al. Neuroimage, DOI://10.1016/j.neuroimage.2020.116828 (2020)
The quaternary assembly of KRas4B with Raf-1 at the membrane Jang, H; Zhang, M; Nussinov, R; Comput Struct Biotechnol J, DOI://10.1016/j.csbj.2020.03.018 (2020)
Continuous chromosome-scale haplotypes assembled from a single interspecies F1 hybrid of yak and cattle Rice, ES; Koren, S; Rhie, A et al. Gigascience, DOI://10.1093/gigascience/giaa029 (2020)
Structures of AAA protein translocase Bcs1 suggest translocation mechanism of a folded protein Tang, WK; Borgnia, MJ; Hsu, AL et al. Nat. Struct. Mol. Biol., DOI://10.1038/s41594-020-0373-0 (2020)
Predisposition to hematologic malignancies in patients with xeroderma pigmentosum Oetjen, KA; Levoska, MA; Tamura, D et al. Haematologica, DOI://10.3324/haematol.2019.223370 (2020)

Levels of early-childhood behavioral inhibition predict distinct neurodevelopmental pathways to pediatric anxiety Abend, R; Swetlitz, C; White, LK et al. Psychol Med, DOI://10.1017/S0033291718003999 (2020)
Structure elucidation and absolute configuration of metabolites from the soil-derived fungus Dictyosporium digitatum using spectroscopic and computational methods Tran, TD; Wilson, BAP; Henrich, CJ et al. Phytochemistry, DOI://10.1016/j.phytochem.2020.112278 (2020)
Differential DNA Methylation in Placenta Associated With Maternal Blood Pressure During Pregnancy Workalemahu, T; Ouidir, M; Shrestha, D; Wu, J; Grantz, KL; Tekola-Ayele, F; Hypertension, DOI://10.1161/HYPERTENSIONAHA.119.14509 (2020)
Family-based exome sequencing identifies rare coding variants in age-related macular degeneration Ratnapriya, R; Acar, İE; Geerlings, MJ et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddaa057 (2020)
Next-generation sequencing of the intrahepatic antibody repertoire delineates a unique B-cell response in HBV-associated acute liver failure Chen, Z; Shen, CH; Engle, RE et al. J. Viral Hepat., DOI://10.1111/jvh.13290 (2020)
Interaction between Epithelial Sodium Channel γ-Subunit and Claudin-8 Modulates Paracellular Sodium Permeability in Renal Collecting Duct Sassi, A; Wang, Y; Chassot, A et al. J. Am. Soc. Nephrol., DOI://10.1681/ASN.2019080790 (2020)
CRISPR-Cas9/phosphoproteomics identifies multiple noncanonical targets of myosin light chain kinase Isobe, K; Raghuram, V; Krishnan, L; Chou, CL; Yang, CR; Knepper, MA; Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00431.2019 (2020)
Genotype-phenotype association and variant characterization in Diamond-Blackfan anemia caused by pathogenic variants in RPL35A Gianferante, DM; Wlodarski, MW; Atsidaftos, E et al. Haematologica, DOI://10.3324/haematol.2020.246629 (2020)
Comprehensive RNA-Seq analysis of notochord-enriched genes induced during Xenopus tropicalis tail resorption Nakajima, K; Tanizaki, Y; Luu, N; Zhang, H; Shi, YB; Gen. Comp. Endocrinol., DOI://10.1016/j.ygcen.2019.113349 (2020)
Retinal Organoids derived from hiPSCs of an AIPL1-LCA Patient Maintain Cytoarchitecture despite Reduced levels of Mutant AIPL1 Lukovic, D; Artero Castro, A; Kaya, KD et al. Sci Rep, DOI://10.1038/s41598-020-62047-2 (2020)
mTORC2/Rac1 Pathway Predisposes Cancer Aggressiveness in IDH1-Mutated Glioma Liu, Y; Lu, Y; Li, A et al. Cancers (Basel), DOI://10.3390/cancers12040787 (2020)
Gene co-expression networks are associated with obesity-related traits in kidney transplant recipients Jaime-Lara, RB; Roy, A; Wang, Y; Stanfill, A; Cashion, AK; Joseph, PV; BMC Med Genomics, DOI://10.1186/s12920-020-0702-5 (2020)

RNAseq expression patterns of canine invasive urothelial carcinoma reveal two distinct tumor clusters and shared regions of dysregulation with human bladder tumors Parker, HG; Dhawan, D; Harris, AC et al. BMC Cancer, DOI://10.1186/s12885-020-06737-0 (2020)
Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress Murai, J; Zhang, H; Pongor, L et al. Cell Rep, DOI://10.1016/j.celrep.2020.02.117 (2020)
Suppressing proteasome mediated processing of topoisomerase II DNA-protein complexes preserves genome integrity Sciascia, N; Wu, W; Zong, D et al. Elife, DOI://10.7554/eLife.53447 (2020)
Understanding the Cause and Consequence of Tumor Heterogeneity Khatib, S; Pomyen, Y; Dang, H; Wang, XW; , Trends Cancer, DOI://10.1016/j.trecan.2020.01.010 (2020)
YAP1/TAZ-TEAD transcriptional networks maintain skin homeostasis by regulating cell proliferation and limiting KLF4 activity Yuan, Y; Park, J; Feng, A et al. Nat Commun, DOI://10.1038/s41467-020-15301-0 (2020)
De novo assembly of the cattle reference genome with single-molecule sequencing Rosen, BD; Bickhart, DM; Schnabel, RD et al. Gigascience, DOI://10.1093/gigascience/giaa021 (2020)
Association of polygenic score for major depression with response to lithium in patients with bipolar disorder Amare, AT; Schubert, KO; Hou, L et al. Mol. Psychiatry, DOI://10.1038/s41380-020-0689-5 (2020)
Stylized versus voxel phantoms: a juxtaposition of organ depth distributions Griffin, KT; Cuthbert, TA; Dewji, SA; Lee, C; Phys Med Biol, DOI://10.1088/1361-6560/ab7686 (2020)
Tautomer Database: A Comprehensive Resource for Tautomerism Analyses Dhaked, DK; Guasch, L; Nicklaus, MC; J Chem Inf Model, DOI://10.1021/acs.jcim.9b01156 (2020)
Toward a Comprehensive Treatment of Tautomerism in Chemoinformatics Including in InChI V2 Dhaked, DK; Ihlenfeldt, WD; Patel, H; Delannée, V; Nicklaus, MC; J Chem Inf Model, DOI://10.1021/acs.jcim.9b01080 (2020)
Multiple testing correction overcontrasts for brain imaging Alberton, BAV; Nichols, TE; Gamba, HR; Winkler, AM; Neuroimage, DOI://10.1016/j.neuroimage.2020.116760 (2020)
Prediction of stress and drug craving ninety minutes in the future with passively collected GPS data Epstein, DH; Tyburski, M; Kowalczyk, WJ et al. NPJ Digit Med, DOI://10.1038/s41746-020-0234-6 (2020)

Analysis of DNA methylation patterns in the tumor immune microenvironment of metastatic melanoma Mitra, S; Lauss, M; Cabrita, R et al. Mol Oncol, DOI://10.1002/1878-0261.12663 (2020)
Distinct inactive conformations of the dopamine D2 and D3 receptors correspond to different extents of inverse agonism Lane, JR; Abramyan, AM; Adhikari, P et al. Elife, DOI://10.7554/eLife.52189 (2020)
Modulating the Stiffness of the Myosin VI Single α-Helical Domain Barnes, CA; Shen, Y; Ying, J; Bax, A; Biophys. J., DOI://10.1016/j.bpj.2020.01.003 (2020)
Interplay between DNA damage repair and apoptosis shapes cancer evolution through aneuploidy and microsatellite instability Auslander, N; Wolf, YI; Koonin, EV; Nat Commun, DOI://10.1038/s41467-020-15094-2 (2020)
Outcome-related signatures identified by Whole Transcriptome Sequencing of Resectable Stage III/IV Melanoma Evaluated After Starting Hu14.18-IL2 Yang, RK; Kuznetsov, IB; Ranheim, EA et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-19-3294 (2020)
Longitudinal Positron Emission Tomography of Dopamine Synthesis in Subjects with GBA1 Mutations Lopez, G; Eisenberg, DP; Gregory, MD et al. Ann. Neurol., DOI://10.1002/ana.25692 (2020)

Combining fMRI during resting state and an attention bias task in children Harrewijn, A; Abend, R; Linke, J et al. Neuroimage, DOI://10.1016/j.neuroimage.2019.116301 (2020)
Sex-biased trajectories of amygdalo-hippocampal morphology change over human development Fish, AM; Nadig, A; Seidlitz, J et al. Neuroimage, DOI://10.1016/j.neuroimage.2019.116122 (2020)
Stem Cell-Derived Endothelial Cell Model that Responds to Tobacco Smoke Like Primary Endothelial Cells Chu, PH; Chen, G; Kuo, D et al. Chem. Res. Toxicol., DOI://10.1021/acs.chemrestox.9b00363 (2020)
Multiple lipid binding sites determine the affinity of PH domains for phosphoinositide-containing membranes Yamamoto, E; Domanski, J; Naughton, FB et al. Sci Adv, DOI://10.1126/sciadv.aay5736 (2020)
Tick-Borne Encephalitis Virus Infection Alters the Sialome of Ixodes ricinus Ticks During the Earliest Stages of Feeding Hart, CE; Ribeiro, JM; Kazimirova, M; Thangamani, S; Front Cell Infect Microbiol, DOI://10.3389/fcimb.2020.00041 (2020)
Low-frequency parietal repetitive transcranial magnetic stimulation reduces fear and anxiety Balderston, NL; Beydler, EM; Goodwin, M et al. Transl Psychiatry, DOI://10.1038/s41398-020-0751-8 (2020)

Molecular and cellular determinants of motor asymmetry in zebrafish Horstick, EJ; Bayleyen, Y; Burgess, HA; Nat Commun, DOI://10.1038/s41467-020-14965-y (2020)
C. elegans pronuclei fuse after fertilization through a novel membrane structure Rahman, M; Chang, IY; Harned, A et al. J. Cell Biol., DOI://10.1083/jcb.201909137 (2020)
Measurement of differential chromatin interactions with absolute quantification of architecture (AQuA-HiChIP) Gryder, BE; Khan, J; Stanton, BZ; Nat Protoc, DOI://10.1038/s41596-019-0285-9 (2020)
Characterizing Adult Cochlear Supporting Cell Transcriptional Diversity Using Single-Cell RNA-Seq: Validation in the Adult Mouse and Translational Implications for the Adult Human Cochlea Hoa, M; Olszewski, R; Li, X et al. Front Mol Neurosci, DOI://10.3389/fnmol.2020.00013 (2020)
Oncogenic K-Ras4B Dimerization Enhances Downstream Mitogen-activated Protein Kinase Signaling Muratcioglu, S; Aydin, C; Odabasi, E et al. J. Mol. Biol., DOI://10.1016/j.jmb.2020.01.002 (2020)
Modeling repeated labor curves in consecutive pregnancies: Individualized prediction of labor progression from previous pregnancy data Buhule, OD; Choo-Wosoba, H; Albert, PS; Stat Med, DOI://10.1002/sim.8462 (2020)

Serial evaluation of CD19 surface expression in pediatric B-cell malignancies following CD19-targeted therapy Libert, D; Yuan, CM; Masih, KE et al. Leukemia, DOI://10.1038/s41375-020-0760-x (2020)
Integrative analysis suggests cell type-specific decoding of NF-κB dynamics Martin, EW; Pacholewska, A; Patel, H; Dashora, H; Sung, MH; Sci Signal, DOI://10.1126/scisignal.aax7195 (2020)
Distribution and evolution of the serine/aspartate racemase family in plants Uda, K; Edashige, Y; Nishimura, R et al. Phytochemistry, DOI://10.1016/j.phytochem.2019.112164 (2020)
Dense Transposon Integration Reveals Essential Cleavage and Polyadenylation Factors Promote Heterochromatin Formation Lee, SY; Hung, S; Esnault, C et al. Cell Rep, DOI://10.1016/j.celrep.2020.01.094 (2020)
Low Serum Insulinlike Growth Factor II Levels Correlate with High BMI in American Indian Adults Muller, YL; Hanson, RL; Mahkee, D et al. Obesity (Silver Spring), DOI://10.1002/oby.22741 (2020)
CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG Liu, Z; Zhang, X; Lei, H et al. Nat Commun, DOI://10.1038/s41467-020-14684-4 (2020)

A case report of multiple primary prostate tumors with differential drug sensitivity Wilkinson, S; Harmon, SA; Terrigino, NT et al. Nat Commun, DOI://10.1038/s41467-020-14657-7 (2020)
A resource for the detailed 3D mapping of white matter pathways in the marmoset brain Liu, C; Ye, FQ; Newman, JD et al. Nat. Neurosci., DOI://10.1038/s41593-019-0575-0 (2020)
The Pharmacopea within Triatomine Salivary Glands Santiago, PB; de Araújo, CN; Charneau, S et al. Trends Parasitol., DOI://10.1016/j.pt.2019.12.014 (2020)
MY-5445, a phosphodiesterase type 5 inhibitor, resensitizes ABCG2-overexpressing multidrug-resistant cancer cells to cytotoxic anticancer drugs Wu, CP; Lusvarghi, S; Tseng, PJ et al. Am J Cancer Res, 2156-6976 (2020)
The Glu102 mutation disrupts higher-order oligomerization of the sigma 1 receptor Abramyan, AM; Yano, H; Xu, M et al. Comput Struct Biotechnol J, DOI://10.1016/j.csbj.2019.12.012 (2020)
High-Affinity Interactions of the nSH3/cSH3 Domains of Grb2 with the C-Terminal Proline-Rich Domain of SOS1 Liao, TJ; Jang, H; Nussinov, R; Fushman, D; J. Am. Chem. Soc., DOI://10.1021/jacs.9b10710 (2020)
Placental DNA methylation changes associated with maternal prepregnancy BMI and gestational weight gain Shrestha, D; Ouidir, M; Workalemahu, T; Zeng, X; Tekola-Ayele, F; Int J Obes (Lond), DOI://10.1038/s41366-020-0546-2 (2020)
Refining genome-wide associated loci for serum uric acid in individuals with African ancestry Chen, G; Shriner, D; Doumatey, AP et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddz272 (2020)
A customizable deep learning model for nosocomial risk prediction from critical care notes with indirect supervision Goodwin, TR; Demner-Fushman, D; J Am Med Inform Assoc, DOI://10.1093/jamia/ocaa004 (2020)
Transcriptional profiling and physiological roles of Aedes aegypti spermathecal-related genes Pascini, TV; Ramalho-Ortigão, M; Ribeiro, JM; Jacobs-Lorena, M; Martins, GF; BMC Genomics, DOI://10.1186/s12864-020-6543-y (2020)
Author Correction: Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans Mitchell, KA; Nichols, N; Tang, W et al. Nat Commun, DOI://10.1038/s41467-020-14448-0 (2020)
Comprehensive Transcriptome Profiling of Cryptic CBFA2T3-GLIS2 Fusion-Positive AML Defines Novel Therapeutic Options: A COG and TARGET Pediatric AML Study Smith, JL; Ries, RE; Hylkema, T et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-19-1800 (2020)

TCR Repertoires of Thymic Conventional and Regulatory T Cells: Identification and Characterization of Both Unique and Shared TCR Sequences Ko, A; Watanabe, M; Nguyen, T et al. J. Immunol., DOI://10.4049/jimmunol.1901006 (2020)
Evaluating global brain connectivity as an imaging marker for depression: influence of preprocessing strategies and placebo-controlled ketamine treatment Kraus, C; Mkrtchian, A; Kadriu, B; Nugent, AC; Zarate, CA; Evans, JW; Neuropsychopharmacology, DOI://10.1038/s41386-020-0624-0 (2020)
CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention Pugacheva, EM; Kubo, N; Loukinov, D et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1911708117 (2020)
Discovery of several thousand highly diverse circular DNA viruses Tisza, MJ; Pastrana, DV; Welch, NL et al. Elife, DOI://10.7554/eLife.51971 (2020)
Sub-millimeter fMRI reveals multiple topographical digit representations that form action maps in human motor cortex Huber, L; Finn, ES; Handwerker, DA et al. Neuroimage, DOI://10.1016/j.neuroimage.2019.116463 (2020)
Truncated tetrahedral RNA nanostructures exhibit enhanced features for delivery of RNAi substrates Zakrevsky, P; Kasprzak, WK; Heinz, WF et al. Nanoscale, DOI://10.1039/c9nr08197f (2020)

SAMPL6 logP challenge: machine learning and quantum mechanical approaches Patel, P; Kuntz, DM; Jones, MR; Brooks, BR; Wilson, AK; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-020-00287-0 (2020)
A deep learning approach for the blind logP prediction in SAMPL6 challenge Prasad, S; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-020-00292-3 (2020)
Whole Genome Sequence-Based Haplotypes Reveal a Single Origin of the 1393 Bp HBB Deletion Wang, X; Xu, JZ; Conrey, A et al. J. Med. Genet., DOI://10.1136/jmedgenet-2019-106698 (2020)
Complete Genome Sequence of Myophage Ec_Makalu_002, Which Infects Uropathogenic Escherichia coli Dhungana, G; Malla, R; Rajaure, M; Adhya, S; Microbiol Resour Announc, DOI://10.1128/MRA.01530-19 (2020)
A dual apolipoprotein C-II mimetic-apolipoprotein C-III antagonist peptide lowers plasma triglycerides Wolska, A; Lo, L; Sviridov, DO et al. Sci Transl Med, DOI://10.1126/scitranslmed.aaw7905 (2020)
Characterization of Specific Ion Effects on PI(4,5)P 2 Clustering: Molecular Dynamics Simulations and Graph-Theoretic Analysis Han, K; Gericke, A; Pastor, RW; J Phys Chem B, DOI://10.1021/acs.jpcb.9b10951 (2020)

In search of genetic factors predisposing to familial hairy cell leukemia (HCL): exome-sequencing of four multiplex HCL pedigrees Pemov, A; Pathak, A; Jones, SJ et al. Leukemia, DOI://10.1038/s41375-019-0702-7 (2020)
ABC-transporter upregulation mediates resistance to the CDK7 inhibitors THZ1 and ICEC0942 Sava, GP; Fan, H; Fisher, RA et al. Oncogene, DOI://10.1038/s41388-019-1008-y (2020)
Abl Signaling Directs Growth of a Pioneer Axon in Drosophila by Shaping the Intrinsic Fluctuations of Actin Clarke, A; McQueen, PG; Fang, HY et al. Mol. Biol. Cell, DOI://10.1091/mbc.E19-10-0564 (2020)
Information-limiting correlations in large neural populations Bartolo, R; Saunders, RC; Mitz, AR; Averbeck, BB; J. Neurosci., DOI://10.1523/JNEUROSCI.2072-19.2019 (2020)
Cytosine base editor 4 but not adenine base editor generates off-target mutations in mouse embryos Lee, HK; Smith, HE; Liu, C; Willi, M; Hennighausen, L; Commun Biol, DOI://10.1038/s42003-019-0745-3 (2020)
A Transcriptome-Wide Association Study (TWAS) Identifies Novel Candidate Susceptibility Genes for Pancreatic Cancer Zhong, J; Jermusyk, A; Wu, L et al. J. Natl. Cancer Inst., DOI://10.1093/jnci/djz246 (2020)

Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease Lalaoui, N; Boyden, SE; Oda, H et al. Nature, DOI://10.1038/s41586-019-1828-5 (2020)
Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation Di Gioia, M; Spreafico, R; Springstead, JR et al. Nat. Immunol., DOI://10.1038/s41590-019-0539-2 (2020)
Mammalian Surface Display Screening of Diverse Cystine-Dense Peptide Libraries for Difficult-to-Drug Targets Crook, ZR; Sevilla, GP; Mhyre, AJ; Olson, JM; Methods Mol. Biol., DOI://10.1007/978-1-4939-9853-1_21 (2020)
Whole Exome Sequencing of Highly Aggregated Lung Cancer Families Reveals Linked Loci for Increased Cancer Risk on Chromosomes 12q, 7p, and 4q Musolf, AM; Moiz, BA; Sun, H et al. Cancer Epidemiol. Biomarkers Prev., DOI://10.1158/1055-9965.EPI-19-0887 (2020)

2019 (522 papers)

A novel HIV-1 protease inhibitor, GRL-044, has potent activity against various HIV-1s with an extremely high genetic barrier to the emergence of HIV-1 drug resistance Aoki, M; Chang, SB; Das, D et al. Glob Health Med, DOI://10.35772/ghm.2019.01003 (2019)
MAIT cells are imprinted by the microbiota in early life and promote tissue repair Constantinides, MG; Link, VM; Tamoutounour, S et al. Science, DOI://10.1126/science.aax6624 (2019)

Amphetamines signal through intracellular TAAR1 receptors coupled to Gα13 and GαS in discrete subcellular domains Underhill, SM; Hullihen, PD; Chen, J et al. Mol. Psychiatry, DOI://10.1038/s41380-019-0469-2 (2019)
GATA3-Controlled Nucleosome Eviction Drives MYC Enhancer Activity in T-cell Development and Leukemia Belver, L; Yang, AY; Albero, R et al. Cancer Discov, DOI://10.1158/2159-8290.CD-19-0471 (2019)
Sptlc1 is essential for myeloid differentiation and hematopoietic homeostasis Parthibane, V; Acharya, D; Srideshikan, SM et al. Blood Adv, DOI://10.1182/bloodadvances.2019000729 (2019)
Genome-Wide Association Study in Irradiated Childhood Cancer Survivors Identifies HTR2A for Subsequent Basal Cell Carcinoma Sapkota, Y; Turcotte, LM; Ehrhardt, MJ et al. J. Invest. Dermatol., DOI://10.1016/j.jid.2019.02.029 (2019)
Mapping histone modifications in low cell number and single cells using antibody-guided chromatin tagmentation (ACT-seq) Carter, B; Ku, WL; Kang, JY et al. Nat Commun, DOI://10.1038/s41467-019-11559-1 (2019)
Cryo-EM reveals active site coordination within a multienzyme pre-rRNA processing complex Pillon, MC; Hsu, AL; Krahn, JM et al. Nat. Struct. Mol. Biol., DOI://10.1038/s41594-019-0289-8 (2019)

Beyond Synthetic Lethality: Charting the Landscape of Pairwise Gene Expression States Associated with Survival in Cancer Magen, A; Das Sahu, A; Lee, JS et al. Cell Rep, DOI://10.1016/j.celrep.2019.06.067 (2019)
ATP-dependent thermostabilization of human P-glycoprotein (ABCB1) is blocked by modulators Lusvarghi, S; Ambudkar, SV; , Biochem. J., DOI://10.1042/BCJ20190736 (2019)
Organ Doses from Chest Radiographs in Tuberculosis Patients in Canada and Their Uncertainties in Periods from 1930 to 1969 Kocher, DC; Apostoaei, AI; Thomas, BA; Borrego, D; Lee, C; Zablotska, LB; , Health Phys, DOI://10.1097/HP.0000000000001171 (2019)
Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals Mandaviya, PR; Joehanes, R; Brody, J et al. Am. J. Clin. Nutr., DOI://10.1093/ajcn/nqz031 (2019)
PARP1 inhibition alleviates injury in ARH3-deficient mice and human cells Mashimo, M; Bu, X; Aoyama, K et al. JCI Insight, DOI://10.1172/jci.insight.124519 (2019)
Placental malaria vaccine candidate antigen VAR2CSA displays atypical domain architecture in some Plasmodium falciparum strains Doritchamou, JYA; Morrison, R; Renn, JP et al. Commun Biol, DOI://10.1038/s42003-019-0704-z (2019)

The Selective Class IIa Histone Deacetylase Inhibitor TMP195 Resensitizes ABCB1- and ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Cytotoxic Anticancer Drugs Wu, CP; Lusvarghi, S; Wang, JC et al. Int J Mol Sci, DOI://10.3390/ijms21010238 (2019)
Assessment of APOE in atypical parkinsonism syndromes Sabir, MS; Blauwendraat, C; Ahmed, S et al. Neurobiol. Dis., DOI://10.1016/j.nbd.2019.02.016 (2019)
SLC35A2-CDG: Functional characterization, expanded molecular, clinical, and biochemical phenotypes of 30 unreported Individuals Ng, BG; Sosicka, P; Agadi, S et al. Hum. Mutat., DOI://10.1002/humu.23731 (2019)
Association between epigenetic age acceleration and depressive symptoms in a prospective cohort study of urban-dwelling adults Beydoun, MA; Hossain, S; Chitrala, KN et al. J Affect Disord, DOI://10.1016/j.jad.2019.06.032 (2019)
Time-lapse Live Imaging and Quantification of Fast Dendritic Branch Dynamics in Developing Drosophila Neurons Sheng, C; Javed, U; Rosenthal, J; Yin, J; Qin, B; Yuan, Q; J Vis Exp, DOI://10.3791/60287 (2019)
The Genetic Architecture of Parkinson Disease in Spain: Characterizing Population-Specific Risk, Differential Haplotype Structures, and Providing Etiologic Insight Bandres-Ciga, S; Ahmed, S; Sabir, MS et al. Mov. Disord., DOI://10.1002/mds.27864 (2019)

Gene signature predictive of hepatocellular carcinoma patient response to transarterial chemoembolization Fako, V; Martin, SP; Pomyen, Y et al. Int. J. Biol. Sci., DOI://10.7150/ijbs.39534 (2019)
Assessment of the Association of D2 Dopamine Receptor Gene and Reported Allele Frequencies With Alcohol Use Disorders: A Systematic Review and Meta-analysis Jung, Y; Montel, RA; Shen, PH; Mash, DC; Goldman, D; JAMA Netw Open, DOI://10.1001/jamanetworkopen.2019.14940 (2019)
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies Nalls, MA; Blauwendraat, C; Vallerga, CL et al. Lancet Neurol, DOI://10.1016/S1474-4422(19)30320-5 (2019)
Resistin-like Molecule α Provides Vitamin-A-Dependent Antimicrobial Protection in the Skin Harris, TA; Gattu, S; Propheter, DC et al. Cell Host Microbe, DOI://10.1016/j.chom.2019.04.004 (2019)
Complementary Task Structure Representations in Hippocampus and Orbitofrontal Cortex during an Odor Sequence Task Zhou, J; Montesinos-Cartagena, M; Wikenheiser, AM; Gardner, MPH; Niv, Y; Schoenbaum, G; Curr. Biol., DOI://10.1016/j.cub.2019.08.040 (2019)
Negative-Stain Transmission Electron Microscopy of Molecular Complexes for Image Analysis by 2D Class Averaging Gallagher, JR; Kim, AJ; Gulati, NM; Harris, AK; Curr Protoc Microbiol, DOI://10.1002/cpmc.90 (2019)

NAA10 polyadenylation signal variants cause syndromic microphthalmia Johnston, JJ; Williamson, KA; Chou, CM et al. J. Med. Genet., DOI://10.1136/jmedgenet-2018-105836 (2019)
Immunoelectron Microscopy of Viral Antigens Gulati, NM; Torian, U; Gallagher, JR; Harris, AK; Curr Protoc Microbiol, DOI://10.1002/cpmc.86 (2019)
The nucleoporin ELYS regulates nuclear size by controlling NPC number and nuclear import capacity Jevtić, P; Schibler, AC; Wesley, CC; Pegoraro, G; Misteli, T; Levy, DL; , EMBO Rep., DOI://10.15252/embr.201847283 (2019)
Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma Gryder, BE; Pomella, S; Sayers, C et al. Nat. Genet., DOI://10.1038/s41588-019-0534-4 (2019)
Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma Yeung, C; Gibson, AE; Issaq, SH et al. Cancer Res., DOI://10.1158/0008-5472.CAN-19-0217 (2019)
Intra-Vκ Cluster Recombination Shapes the Ig Kappa Locus Repertoire Shinoda, K; Maman, Y; Canela, A; Schatz, DG; Livak, F; Nussenzweig, A; , Cell Rep, DOI://10.1016/j.celrep.2019.11.088 (2019)

Targeting the Chromosomal Passenger Complex Subunit INCENP Induces Polyploidization, Apoptosis, and Senescence in Neuroblastoma Sun, M; Veschi, V; Bagchi, S et al. Cancer Res., DOI://10.1158/0008-5472.CAN-19-0695 (2019)
Meta-analysis of Chromatin Programming by Steroid Receptors Paakinaho, V; Swinstead, EE; Presman, DM; Grøntved, L; Hager, GL; , Cell Rep, DOI://10.1016/j.celrep.2019.08.039 (2019)
Sympathetic activity contributes to the fMRI signal Özbay, PS; Chang, C; Picchioni, D et al. Commun Biol, DOI://10.1038/s42003-019-0659-0 (2019)
Evidence for a Causal Role of the SH2B3-β 2 M Axis in Blood Pressure Regulation Keefe, JA; Hwang, SJ; Huan, T et al. Hypertension, DOI://10.1161/HYPERTENSIONAHA.118.12094 (2019)
Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus Mistry, P; Nakabo, S; O'Neil, L et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1908576116 (2019)
The Bone Marrow Protects and Optimizes Immunological Memory during Dietary Restriction Collins, N; Han, SJ; Enamorado, M et al. Cell, DOI://10.1016/j.cell.2019.07.049 (2019)
Relationship between human leukocyte antigen alleles and risk of Kaposi's sarcoma in Cameroon Cornejo Castro, EM; Morrison, BJ; Marshall, VA et al. Genes Immun., DOI://10.1038/s41435-019-0077-9 (2019)
Integration of TGF-β-induced Smad signaling in the insulin-induced transcriptional response in endothelial cells Budi, EH; Hoffman, S; Gao, S; Zhang, YE; Derynck, R; , Sci Rep, DOI://10.1038/s41598-019-53490-x (2019)
Development of R7BP inhibitors through cross-linking coupled mass spectrometry and integrated modeling Adikaram, PR; Zhang, JH; Kittock, CM et al. Commun Biol, DOI://10.1038/s42003-019-0585-1 (2019)
Differential expression and subcellular localization of Copines in mouse retina Goel, M; Li, T; Badea, TC; J. Comp. Neurol., DOI://10.1002/cne.24684 (2019)
Identification of Novel Pathways Associated with Patterned Cerebellar Purkinje Neuron Degeneration in Niemann-Pick Disease, Type C1 Martin, KB; Williams, IM; Cluzeau, CV et al. Int J Mol Sci, DOI://10.3390/ijms21010292 (2019)
A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers El Khattabi, L; Zhao, H; Kalchschmidt, J et al. Cell, DOI://10.1016/j.cell.2019.07.011 (2019)
Temperature-dependent regulation of upstream open reading frame translation in S. cerevisiae Kulkarni, SD; Zhou, F; Sen, ND; Zhang, H; Hinnebusch, AG; Lorsch, JR; BMC Biol., DOI://10.1186/s12915-019-0718-5 (2019)
A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity Bradfield, JP; Vogelezang, S; Felix, JF et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddz161 (2019)
Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice Wang, Z; Xu, X; Li, JL; Palmer, C; Maric, D; Dean, J; Nat Commun, DOI://10.1038/s41467-019-13193-3 (2019)
A Peripheral Blood DNA Methylation Signature of Hepatic Fat Reveals a Potential Causal Pathway for Nonalcoholic Fatty Liver Disease Ma, J; Nano, J; Ding, J et al. Diabetes, DOI://10.2337/DB18-1193 (2019)
Liver- and Microbiome-derived Bile Acids Accumulate in Human Breast Tumors and Inhibit Growth and Improve Patient Survival Tang, W; Putluri, V; Ambati, CR; Dorsey, TH; Putluri, N; Ambs, S; , Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-19-0094 (2019)
ARSA variants in α-synucleinopathies Makarious, MB; Diez-Fairen, M; Krohn, L et al. Brain, DOI://10.1093/brain/awz340 (2019)

A New Lineage of Cryptococcus gattii (VGV) Discovered in the Central Zambezian Miombo Woodlands Farrer, RA; Chang, M; Davis, MJ et al. mBio, DOI://10.1128/mBio.02306-19 (2019)
Contribution of SLC22A12 on hypouricemia and its clinical significance for screening purposes Cha, DH; Gee, HY; Cachau, R et al. Sci Rep, DOI://10.1038/s41598-019-50798-6 (2019)
Dose coefficients of mesh-type ICRP reference computational phantoms for external exposures of neutrons, protons, and helium ions Yeom YS, Choi C, et al. Nuc. Engg. Tech., doi://10.1016/j.net.2019.12.020 (2019)
White Blood Cell Count and Risk of Incident Lung Cancer in the UK Biobank Wong JYY, Bassig BA et al. JNCI Cancer Spectrum, doi://10.1093/jncics/pkz102 (2019)
Cryo-EM structure of substrate-free E. coli Lon protease provides insights into the dynamics of Lon machinery Botos I, Lountos GT et al. Cur. Res. Struct. Biol. , doi://0.1016/j.crstbi.2019.10.001 (2019)
Dosimetric impact of voxel resolutions of computational human phantoms for external photon exposure Choonsik Lee, Andreu Badal, Yeon Soo Yeom, Keith T Griffin and Dayton McMillan Biomed. Phys. Engg. Exp. , doi://10.1088/2057-1976/ab2850 (2019)
Joint modelling of competing risks and current status data: an application to a spontaneous labour study Youjin Lee Mei; Cheng Wang; Katherine L. Grantz; Rajeshwari Sundaram Royal Statistical Society, doi://10.1111/rssc.12351 (2019)
Keratinocyte-intrinsic MHCII expression controls microbiota-induced Th1 cell responses Tamoutounour, S; Han, SJ; Deckers, J et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1912432116 (2019)
Mammographic breast density and its association with urinary estrogens and the fecal microbiota in postmenopausal women Jones, GS; Spencer Feigelson, H; Falk, RT et al. PLoS ONE, DOI://10.1371/journal.pone.0216114 (2019)
NMR Analysis of Apo Glutamine-Binding Protein Exposes Challenges in the Study of Interdomain Dynamics Kooshapur, H; Ma, J; Tjandra, N; Bermejo, GA; Angew. Chem. Int. Ed. Engl., DOI://10.1002/anie.201911015 (2019)
Proteomics Pipeline for Identifying Variant Proteins in Plasmodium falciparum Parasites Isolated from Children Presenting with Malaria Gonzales Hurtado, PA; Morrison, R; Ribeiro, JMC et al. J. Proteome Res., DOI://10.1021/acs.jproteome.9b00169 (2019)
Oncoviruses Can Drive Cancer by Rewiring Signaling Pathways Through Interface Mimicry Guven-Maiorov, E; Tsai, CJ; Nussinov, R; , Front Oncol, DOI://10.3389/fonc.2019.01236 (2019)
Rat Orbitofrontal Ensemble Activity Contains Multiplexed but Dissociable Representations of Value and Task Structure in an Odor Sequence Task Zhou, J; Gardner, MPH; Stalnaker, TA et al. Curr. Biol., DOI://10.1016/j.cub.2019.01.048 (2019)
Non-Leishmania Parasite in Fatal Visceral Leishmaniasis-Like Disease, Brazil Maruyama, SR; de Santana, AKM; Takamiya, NT et al. Emerging Infect. Dis., DOI://10.3201/eid2511.181548 (2019)
A Phase II Study of Tumor-infiltrating Lymphocyte Therapy for Human Papillomavirus-associated Epithelial Cancers Stevanovic, S; Helman, SR; Wunderlich, JR et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-2722 (2019)
Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans Mitchell, KA; Nichols, N; Tang, W et al. Nat Commun, DOI://10.1038/s41467-019-13732-y (2019)
The endocytic membrane trafficking pathway plays a major role in the risk of Parkinson's disease Bandres-Ciga, S; Saez-Atienzar, S; Bonet-Ponce, L et al. Mov. Disord., DOI://10.1002/mds.27614 (2019)
The GATOR complex regulates an essential response to meiotic double-stranded breaks in Drosophila Wei, Y; Bettedi, L; Ting, CY et al. Elife, DOI://10.7554/eLife.42149 (2019)
Next generation sequencing and the classical HLA loci in full heritage Pima Indians of Arizona: Defining the core HLA variation for North American Paleo-Indians Williams, RC; Knowler, WC; Shuldiner, AR et al. Hum Immunol, DOI://10.1016/j.humimm.2019.10.002 (2019)
Autosomal recessive congenital cataracts linked to HSF4 in a consanguineous Pakistani family Jiao, X; Khan, SY; Kaul, H et al. PLoS ONE, DOI://10.1371/journal.pone.0225010 (2019)
White Matter Microstructure in Pediatric Bipolar Disorder and Disruptive Mood Dysregulation Disorder Linke, JO; Adleman, NE; Sarlls, J et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2019.05.035 (2019)
DENND5B Regulates Intestinal Triglyceride Absorption and Body Mass Gordon, SM; Neufeld, EB; Yang, Z et al. Sci Rep, DOI://10.1038/s41598-019-40296-0 (2019)
Reply to Spreng et al.: Multiecho fMRI denoising does not remove global motion-associated respiratory signals Power, JD; Lynch, CJ; Gilmore, AW; Gotts, SJ; Martin, A; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1909852116 (2019)
Single molecule analysis of lamin dynamics Serebryannyy, LA; Ball, DA; Karpova, TS; Misteli, T; , Methods, DOI://10.1016/j.ymeth.2018.08.009 (2019)
HNRNPH1-dependent splicing of a fusion oncogene reveals a targetable RNA G-quadruplex interaction Neckles, C; Boer, RE; Aboreden, N et al. RNA, DOI://10.1261/rna.072454.119 (2019)
Head and Neck Cancers Promote an Inflammatory Transcriptome Through Coactivation of Classic and Alternative NF-κB Pathways Yang, X; Cheng, H; Chen, J et al. Cancer Immunol Res, DOI://10.1158/2326-6066.CIR-18-0832 (2019)
Enhancement of LIN28B-induced hematopoietic reprogramming by IGF2BP3 Wang, S; Chim, B; Su, Y et al. Genes Dev., DOI://10.1101/gad.325100.119 (2019)
Genome-Wide Profiling of Cervical RNA-Binding Proteins Identifies Human Papillomavirus Regulation of RNASEH2A Expression by Viral E7 and E2F1 Xu, J; Liu, H; Yang, Y et al. mBio, DOI://10.1128/mBio.02687-18 (2019)
Classification of GBA Variants and Their Effects in Synucleinopathies Gan-Or, Z; Alcalay, RN; Makarious, MB; Scholz, SW; Blauwendraat, C; , ; Mov. Disord., DOI://10.1002/mds.27803 (2019)
H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development Jang, Y; Broun, A; Wang, C et al. Nucleic Acids Res., DOI://10.1093/nar/gky982 (2019)
MicroRNA-mediated control of developmental lymphangiogenesis Jung, HM; Hu, CT; Fister, AM et al. Elife, DOI://10.7554/eLife.46007 (2019)
Immunoprecipitation and Sequencing of Acetylated RNA Arango, D; Sturgill, D; Oberdoerffer, S; , Bio Protoc, DOI://10.21769/BioProtoc.3278 (2019)
Correction: Conserved mRNA-granule component Scd6 targets Dhh1 to repress translation initiation and activates Dcp2-mediated mRNA decay in vivo Zeidan, Q; He, F; Zhang, F; Zhang, H; Jacobson, A; Hinnebusch, AG; PLoS Genet., DOI://10.1371/journal.pgen.1008299 (2019)
Understanding Cancer Through the Lens of Epigenetic Inheritance, Allele-Specific Gene Expression, and High-Throughput Technology Lee, MP Front Oncol, DOI://10.3389/fonc.2019.00794 (2019)
A deconvolution algorithm for multi-echo functional MRI: Multi-echo Sparse Paradigm Free Mapping Caballero-Gaudes, C; Moia, S; Panwar, P; Bandettini, PA; Gonzalez-Castillo, J; Neuroimage, DOI://10.1016/j.neuroimage.2019.116081 (2019)
A tail of two sides: Artificially doubled false positive rates in neuroimaging due to the sidedness choice with t-tests Chen, G; Cox, RW; Glen, DR; Rajendra, JK; Reynolds, RC; Taylor, PA; Hum Brain Mapp, DOI://10.1002/hbm.24399 (2019)
Association of Maternal Exposure to Persistent Organic Pollutants in Early Pregnancy With Fetal Growth Ouidir, M; Buck Louis, GM; Kanner, J et al. JAMA Pediatr, DOI://10.1001/jamapediatrics.2019.5104 (2019)
Modeling ligand docking to RNA in the design of RNA-based nanostructures Kasprzak, WK; Ahmed, NA; Shapiro, BA; Curr. Opin. Biotechnol., DOI://10.1016/j.copbio.2019.10.010 (2019)
Integrating Hi-C links with assembly graphs for chromosome-scale assembly Ghurye, J; Rhie, A; Walenz, BP et al. PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1007273 (2019)
Magnetoencephalographic Correlates of Suicidal Ideation in Major Depression Gilbert, JR; Ballard, ED; Galiano, CS; Nugent, AC; Zarate, CA; Biol Psychiatry Cogn Neurosci Neuroimaging, DOI://10.1016/j.bpsc.2019.11.011 (2019)
Single Cell and Single Nucleus RNA-Seq Reveal Cellular Heterogeneity and Homeostatic Regulatory Networks in Adult Mouse Stria Vascularis Korrapati, S; Taukulis, I; Olszewski, R et al. Front Mol Neurosci, DOI://10.3389/fnmol.2019.00316 (2019)
Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods Hu, X; Compton, JR; Legler, PM; J Vis Exp, DOI://10.3791/60421 (2019)
Anoctamin 8 Tethers Endoplasmic Reticulum and Plasma Membrane for Assembly of Ca 2+ Signaling Complexes at the ER/PM Compartment Jha, A; Chung, WY; Vachel, L et al. EMBO J., DOI://10.15252/embj.2018101452 (2019)
Single-Cell Profiling Defines Transcriptomic Signatures Specific to Tumor-Reactive versus Virus-Responsive CD4+ T Cells Magen, A; Nie, J; Ciucci, T et al. Cell Rep, DOI://10.1016/j.celrep.2019.10.131 (2019)
Transcriptome-based molecular staging of human stem cell-derived retinal organoids uncovers accelerated photoreceptor differentiation by 9-cis retinal Kaya KD, Chen HY, Brooks MJ et al Mol Vis (2019)
Novel Protease Inhibitors Containing C-5-Modified bis-Tetrahydrofuranylurethane and Aminobenzothiazole as P2 and P2' Ligands That Exert Potent Antiviral Activity against Highly Multidrug-Resistant HIV-1 with a High Genetic Barrier against the Emergence of Drug Resistance Takamatsu, Y; Aoki, M; Bulut, H et al. Antimicrob. Agents Chemother., DOI://10.1128/AAC.00372-19 (2019)
Benchmarking the Performance of Time-Dependent Density Functional Theory Methods on Biochromophores Shao, Y; Mei, Y; Sundholm, D; Kaila, VRI; J Chem Theory Comput, DOI://10.1021/acs.jctc.9b00823 (2019)
Novel Central Nervous System (CNS)-Targeting Protease Inhibitors for Drug-Resistant HIV Infection and HIV-Associated CNS Complications Amano, M; Salcedo-Gómez, PM; Yedidi, RS et al. Antimicrob. Agents Chemother., DOI://10.1128/AAC.00466-19 (2019)

HLA and autoantibodies define scleroderma subtypes and risk in African and European Americans and suggest a role for molecular mimicry Gourh, P; Safran, SA; Alexander, T et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1906593116 (2019)
Maternal fatty acid concentrations and newborn DNA methylation Robinson, SL; Mumford, SL; Guan, W et al. Am. J. Clin. Nutr., DOI://10.1093/ajcn/nqz311 (2019)
DHHC20 Palmitoyl-Transferase Reshapes the Membrane to Foster Catalysis Stix, R; Song, J; Banerjee, A; Faraldo-Gómez, JD; Biophys. J., DOI://10.1016/j.bpj.2019.11.003 (2019)
Analysis of ordered composite endpoints Follmann, D; Fay, MP; Hamasaki, T; Evans, S; Stat Med, DOI://10.1002/sim.8431 (2019)
Large-scale state-dependent membrane remodeling by a transporter protein Zhou, W; Fiorin, G; Anselmi, C et al. Elife, DOI://10.7554/eLife.50576 (2019)
CNVScope: Visually Exploring Copy Number Aberrations in Cancer Genomes Dalgleish, JL; Wang, Y; Zhu, J; Meltzer, PS; Cancer Inform, DOI://10.1177/1176935119890290 (2019)

Identification of 102 Correlations between Serum Metabolites and Habitual Diet in a Metabolomics Study of the Prostate, Lung, Colorectal, and Ovarian Cancer Trial Mazzilli, KM; McClain, KM; Lipworth, L et al. J. Nutr., DOI://10.1093/jn/nxz300 (2019)
Permeability of membranes in the liquid ordered and liquid disordered phases Ghysels, A; Krämer, A; Venable, RM et al. Nat Commun, DOI://10.1038/s41467-019-13432-7 (2019)
A Thpok-Directed Transcriptional Circuitry Promotes Bcl6 and Maf Expression to Orchestrate T Follicular Helper Differentiation Vacchio, MS; Ciucci, T; Gao, Y et al. Immunity, DOI://10.1016/j.immuni.2019.06.023 (2019)
SummaryAUC: a tool for evaluating the performance of polygenic risk prediction models in validation datasets with only summary level statistics Song, L; Liu, A; Shi, J; , ; Bioinformatics, DOI://10.1093/bioinformatics/btz176 (2019)
Accurate Prediction for Antibody Resistance of Clinical HIV-1 Isolates Rawi, R; Mall, R; Shen, CH et al. Sci Rep, DOI://10.1038/s41598-019-50635-w (2019)
Gene gain and loss push prokaryotes beyond the homologous recombination barrier and accelerate genome sequence divergence Iranzo, J; Wolf, YI; Koonin, EV; Sela, I; Nat Commun, DOI://10.1038/s41467-019-13429-2 (2019)

Mash Screen: high-throughput sequence containment estimation for genome discovery Ondov, BD; Starrett, GJ; Sappington, A et al. Genome Biol., DOI://10.1186/s13059-019-1841-x (2019)
The scale-invariant, temporal profile of neuronal avalanches in relation to cortical γ-oscillations Miller, SR; Yu, S; Plenz, D; Sci Rep, DOI://10.1038/s41598-019-52326-y (2019)
Myc controls a distinct transcriptional program in fetal thymic epithelial cells that determines thymus growth Cowan, JE; Malin, J; Zhao, Y et al. Nat Commun, DOI://10.1038/s41467-019-13465-y (2019)
Ca2+-Dependent Switch of Calmodulin Interaction Mode with Tandem IQ Motifs in the Scaffolding Protein IQGAP1 Zhang, M; Li, Z; Jang, H; Hedman, AC; Sacks, DB; Nussinov, R; Biochemistry, DOI://10.1021/acs.biochem.9b00854 (2019)
Contribution of Common Genetic Variants to Familial Aggregation of Disease and Implications for Sequencing Studies Schlafly, A; Pfeiffer, RM; Nagore, E et al. PLoS Genet., DOI://10.1371/journal.pgen.1008490 (2019)
Mechanistic link between right prefrontal cortical activity and anxious arousal revealed using transcranial magnetic stimulation in healthy subjects Balderston, NL; Beydler, EM; Roberts, C et al. Neuropsychopharmacology, DOI://10.1038/s41386-019-0583-5 (2019)

Race-specific alterations in DNA methylation among middle-aged African Americans and Whites with metabolic syndrome Chitrala, KN; Hernandez, DG; Nalls, MA et al. Epigenetics, DOI://10.1080/15592294.2019.1695340 (2019)
A3 adenosine receptor activation mechanisms: molecular dynamics analysis of inactive, active, and fully active states Ciancetta, A; Rubio, P; Lieberman, DI; Jacobson, KA; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-019-00246-4 (2019)
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls Flannick, J; Mercader, JM; Fuchsberger, C et al. Nature, DOI://10.1038/s41586-019-1231-2 (2019)
Knowing What You Know in Brain Segmentation Using Bayesian Deep Neural Networks McClure, P; Rho, N; Lee, JA et al. Front Neuroinform, DOI://10.3389/fninf.2019.00067 (2019)
Commensal microbiota drive the functional diversification of colon macrophages Kang, B; Alvarado, LJ; Kim, T et al. Mucosal Immunol, DOI://10.1038/s41385-019-0228-3 (2019)
Rotamer Jumps, Proton Exchange, and Amine Inversion Dynamics of Dimethylated Lysine Residues in Proteins Resolved by pH-Dependent 1H and 13C NMR Relaxation Dispersion Weininger, U; Modig, K; Ishida, H; Vogel, HJ; Akke, M; J Phys Chem B, DOI://10.1021/acs.jpcb.9b06408 (2019)

Single cell analysis of adult mouse skeletal muscle stem cells in homeostatic and regenerative conditions Dell'Orso, S; Juan, AH; Ko, KD et al. Development, DOI://10.1242/dev.174177 (2019)
Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle Taylor, DL; Jackson, AU; Narisu, N et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1814263116 (2019)
Author Correction: Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses Kanekiyo, M; Joyce, MG; Gillespie, RA et al. Nat. Immunol., DOI://10.1038/s41590-019-0395-0 (2019)
Correction: CAPN1 is a novel binding partner and regulator of the tumor suppressor NF1 in melanoma Alon, M; Arafeh, R; Lee, JS et al. Oncotarget, DOI://10.18632/oncotarget.26685 (2019)
Correction: The zinc-finger protein CLAMP promotes gypsy chromatin insulator function in Drosophila (doi:10.1242/jcs.226092) Bag, I; Dale, RK; Palmer, C; Lei, EP; J. Cell. Sci., DOI://10.1242/jcs.231977 (2019)
Multiomic Profiling Identifies cis-Regulatory Networks Underlying Human Pancreatic β Cell Identity and Function Lawlor, N; Márquez, EJ; Orchard, P et al. Cell Rep, DOI://10.1016/j.celrep.2018.12.083 (2019)
Oligonucleotide Preparation Approach for Assembly of DNA Synthons Yantsevich, AV; Shchur, VV; Usanov, SA; SLAS Technol, DOI://10.1177/2472630319850534 (2019)
Second Case of HOIP Deficiency Expands Clinical Features and Defines Inflammatory Transcriptome Regulated by LUBAC Oda, H; Beck, DB; Kuehn, HS et al. Front Immunol, DOI://10.3389/fimmu.2019.00479 (2019)
Katanin Grips the β-Tubulin Tail through an Electropositive Double Spiral to Sever Microtubules Zehr, EA; Szyk, A; Szczesna, E; Roll-Mecak, A; Dev. Cell, DOI://10.1016/j.devcel.2019.10.010 (2019)
Bilateral ureteral obstruction is rapidly accompanied by ER stress and activation of autophagic degradation of IMCD proteins including AQP2 Somparn, P; Boonkrai, C; Charngkaew, K et al. Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00113.2019 (2019)
Data augmentation using generative adversarial networks (CycleGAN) to improve generalizability in CT segmentation tasks Sandfort, V; Yan, K; Pickhardt, PJ; Summers, RM; Sci Rep, DOI://10.1038/s41598-019-52737-x (2019)
Author Correction: In vivo tropism of Salmonella Typhi toxin to cells expressing a multiantennal glycan receptor Yang, YA; Lee, S; Zhao, J et al. Nat Microbiol, DOI://10.1038/s41564-019-0505-7 (2019)
Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression Forstner, AJ; Awasthi, S; Wolf, C et al. Mol. Psychiatry, DOI://10.1038/s41380-019-0590-2 (2019)
Preventing dysbiosis of the neonatal mouse intestinal microbiome protects against late-onset sepsis Singer, JR; Blosser, EG; Zindl, CL et al. Nat. Med., DOI://10.1038/s41591-019-0640-y (2019)
Splicing factor DHX15 affects tp53 and mdm2 expression via alternate splicing and promoter usage McElderry, J; Carrington, B; Bishop, K et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddz261 (2019)
Tango1 coordinates the formation of ER/Golgi docking sites to mediate secretory granule formation Reynolds, HM; Zhang, L; Tran, DT; Ten Hagen, KG; J. Biol. Chem., DOI://10.1074/jbc.RA119.011063 (2019)
Williams syndrome hemideletion and LIMK1 variation both affect dorsal stream functional connectivity Gregory, MD; Mervis, CB; Elliott, ML et al. Brain, DOI://10.1093/brain/awz323 (2019)
Reducing motion sensitivity in 3D high-resolution T2*-weighted MRI by navigator-based motion and nonlinear magnetic field correction Liu, J; van Gelderen, P; de Zwart, JA; Duyn, JH; Neuroimage, DOI://10.1016/j.neuroimage.2019.116332 (2019)

Single-Cell Transcriptome Analysis Reveals Gene Signatures Associated with T-cell Persistence Following Adoptive Cell Therapy Lu, YC; Jia, L; Zheng, Z; Tran, E; Robbins, PF; Rosenberg, SA; Cancer Immunol Res, DOI://10.1158/2326-6066.CIR-19-0299 (2019)
Over-expression of Vitreoscilla hemoglobin (VHb) and flavohemoglobin (FHb) genes greatly enhances pullulan production Xue, SJ; Jiang, H; Chen, L et al. Int. J. Biol. Macromol., DOI://10.1016/j.ijbiomac.2019.04.007 (2019)
Dose coefficients of percentile-specific computational phantoms for photon external exposures Yeom, YS; Han, H; Choi, C; Shin, B; Kim, CH; Lee, C; Radiat Environ Biophys, DOI://10.1007/s00411-019-00818-w (2019)
Characteristics of respiratory measures in young adults scanned at rest, including systematic changes and "missed" deep breaths Power, JD; Lynch, CJ; Dubin, MJ; Silver, BM; Martin, A; Jones, RM; Neuroimage, DOI://10.1016/j.neuroimage.2019.116234 (2019)
Impact of CMV Infection on Natural Killer Cell Clonal Repertoire in CMV-Naïve Rhesus Macaques Truitt, LL; Yang, D; Espinoza, DA et al. Front Immunol, DOI://10.3389/fimmu.2019.02381 (2019)
Prepontine non-giant neurons drive flexible escape behavior in zebrafish Marquart, GD; Tabor, KM; Bergeron, SA; Briggman, KL; Burgess, HA; PLoS Biol., DOI://10.1371/journal.pbio.3000480 (2019)

Approximation of Bias and Mean Squared Error in Two-sample Mendelian Randomization Analyses Deng, L; Zhang, H; Song, L; Yu, K; Biometrics, DOI://10.1111/biom.13169 (2019)
AI Meets Exascale Computing: Advancing Cancer Research With Large-Scale High Performance Computing Bhattacharya, T; Brettin, T; Doroshow, JH et al. Front Oncol, DOI://10.3389/fonc.2019.00984 (2019)
Plasmid Dissemination and Selection of a Multidrug-Resistant Klebsiella pneumoniae Strain during Transplant-Associated Antibiotic Therapy Conlan, S; Lau, AF; Deming, C et al. MBio, DOI://10.1128/mBio.00652-19 (2019)
Stereotyped transcriptomic transformation of somatosensory neurons in response to injury Nguyen, MQ; Le Pichon, CE; Ryba, N; Elife, DOI://10.7554/eLife.49679 (2019)
Cryo-EM structure of the bacterial Ton motor subcomplex ExbB-ExbD provides information on structure and stoichiometry Celia, H; Botos, I; Ni, X et al. Commun Biol, DOI://10.1038/s42003-019-0604-2 (2019)
Dog10K: an international sequencing effort to advance studies of canine domestication, phenotypes and health Ostrander, EA; Wang, GD; Larson, G et al. Natl Sci Rev, DOI://10.1093/nsr/nwz049 (2019)

Single-Cell RNA-seq Identifies Cell Diversity in Embryonic Salivary Glands Sekiguchi, R; Martin, D; , ; Yamada, KM; J. Dent. Res., DOI://10.1177/0022034519883888 (2019)
Embryo polarity in moth flies and mosquitoes relies on distinct old genes with localized transcript isoforms Yoon, Y; Klomp, J; Martin-Martin, I et al. Elife, DOI://10.7554/eLife.46711 (2019)
Differential Nucleosome Spacing in Neurons and Glia Clark, SC; Chereji, RV; Lee, PR; Fields, RD; Clark, DJ; Neurosci. Lett., DOI://10.1016/j.neulet.2019.134559 (2019)
Improved Retinal Organoid Differentiation by Modulating Signaling Pathways Revealed by Comparative Transcriptome Analyses with Development In Vivo Brooks, MJ; Chen, HY; Kelley, RA et al. Stem Cell Reports, DOI://10.1016/j.stemcr.2019.09.009 (2019)
Gata2 deficiency delays leukemogenesis while contributing to aggressive leukemia phenotype in Cbfb-MYH11 knockin mice Saida, S; Zhen, T; Kim, E et al. Leukemia, DOI://10.1038/s41375-019-0605-7 (2019)
Cell Type- and Sex-Dependent Transcriptome Profiles of Rat Anterior Pituitary Cells Fletcher, PA; Smiljanic, K; Maso Prévide, R et al. Front Endocrinol (Lausanne), DOI://10.3389/fendo.2019.00623 (2019)
Differences in Genome-wide DNA Methylation Profiles in Breast Milk by Race and Lactation Duration Davis Lynn, BC; Bodelon, C; Pfeiffer, RM et al. Cancer Prev Res (Phila), DOI://10.1158/1940-6207.CAPR-19-0169 (2019)
Multi-phosphorylation reaction and clustering tune Pom1 gradient mid-cell levels according to cell size Gerganova, V; Floderer, C; Archetti, A et al. Elife, DOI://10.7554/eLife.45983 (2019)
Strong dependence of the nano-bio interactions on core morphology and layer composition of ultrasmall nanostructures Hassan, SA J Chem Phys, DOI://10.1063/1.5115192 (2019)
Discovery and Development of Anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication Maeda, K; Das, D; Kobayakawa, T; Tamamura, H; Takeuchi, H; Curr Top Med Chem, DOI://10.2174/1568026619666190712204603 (2019)
Direct Derivation of Free Energies of Membrane Deformation and Other Solvent Density Variations From Enhanced Sampling Molecular Dynamics Fiorin, G; Marinelli, F; Faraldo-Gómez, JD; J Comput Chem, DOI://10.1002/jcc.26075 (2019)
Clonal tracking of erythropoiesis in rhesus macaques Fan, X; Wu, C; Truitt, LL et al. Haematologica, DOI://10.3324/haematol.2019.231811 (2019)

Molecular Classification of Epithelial Ovarian Cancer Based on Methylation Profiling: Evidence for Survival Heterogeneity Bodelon, C; Killian, JK; Sampson, JN et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-3720 (2019)
Layer-dependent activity in human prefrontal cortex during working memory Finn, ES; Huber, L; Jangraw, DC; Molfese, PJ; Bandettini, PA; Nat. Neurosci., DOI://10.1038/s41593-019-0487-z (2019)
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution Justice, AE; Karaderi, T; Highland, HM et al. Nat. Genet., DOI://10.1038/s41588-018-0334-2 (2019)
Dynamic Emergence of Mismatch Repair Deficiency Facilitates Rapid Evolution of Ceftazidime-Avibactam Resistance in Pseudomonas aeruginosa Acute Infection Khil, PP; Dulanto Chiang, A; Ho, J et al. MBio, DOI://10.1128/mBio.01822-19 (2019)
Drosophila Heterochromatin Stabilization Requires the Zinc-Finger Protein Small Ovary Benner, L; Castro, EA; Whitworth, C et al. Genetics, DOI://10.1534/genetics.119.302590 (2019)
Dual antagonist of cIAP/XIAP ASTX660 sensitizes HPV-and HPV+ head and neck cancers to TNFα, TRAIL, and radiation Therapy Xiao, R; An, Y; Ye, W et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-3802 (2019)
Generation of small molecule-binding RNA arrays and their application to fluorogen-binding RNA aptamers Henderson, CA; Rail, CA; Butt, LE; Vincent, HA; Callaghan, AJ; Methods, DOI://10.1016/j.ymeth.2019.04.021 (2019)
Gene-based association analysis of survival traits via functional regression-based mixed effect cox models for related samples Chiu, CY; Zhang, B; Wang, S et al. Genet. Epidemiol., DOI://10.1002/gepi.22254 (2019)
Molecular characterization of respiratory syncytial viruses circulating in a paediatric cohort in Amman, Jordan Trovão, NS; Khuri-Bulos, N; Tan, Y et al. Microb Genom, DOI://10.1099/mgen.0.000292 (2019)
A Novel Bromine-Containing Paroxetine Analogue Provides Mechanistic Clues for Binding Ambiguity at the Central Primary Binding Site of the Serotonin Transporter Slack, RD; Abramyan, AM; Tang, H et al. ACS Chem Neurosci, DOI://10.1021/acschemneuro.9b00375 (2019)
Low Abundance of Circulating Tumor DNA in Localized Prostate Cancer Hennigan, ST; Trostel, SY; Terrigino, NT et al. JCO Precis Oncol, DOI://10.1200/PO.19.00176 (2019)
Automated Liver Fat Quantification at Nonenhanced Abdominal CT for Population-based Steatosis Assessment Graffy, PM; Sandfort, V; Summers, RM; Pickhardt, PJ; Radiology, DOI://10.1148/radiol.2019190512 (2019)
lncRNA expression predicts mRNA abundance Pacholewska, A; Sung, MH; Epigenomics, DOI://10.2217/epi-2019-0003 (2019)
Quantitative MNase-seq accurately maps nucleosome occupancy levels Chereji, RV; Bryson, TD; Henikoff, S; Genome Biol., DOI://10.1186/s13059-019-1815-z (2019)
Synthesis and Characterization of Bodipy-FL-Cyclosporine A as a Substrate for Multidrug Resistance-Linked P-Glycoprotein (ABCB1) Sajid, A; Raju, N; Lusvarghi, S; Vahedi, S; Swenson, RE; Ambudkar, SV; Drug Metab. Dispos., DOI://10.1124/dmd.119.087734 (2019)
Accessibility of promoter DNA is not the primary determinant of chromatin-mediated gene regulation Chereji, RV; Eriksson, PR; Ocampo, J; Prajapati, HK; Clark, DJ; Genome Res., DOI://10.1101/gr.249326.119 (2019)
Structure of the primed state of the ATPase domain of chromatin remodeling factor ISWI bound to the nucleosome Chittori, S; Hong, J; Bai, Y; Subramaniam, S; Nucleic Acids Res., DOI://10.1093/nar/gkz670 (2019)
De Novo Variants in WDR37 Are Associated with Epilepsy, Colobomas, Dysmorphism, Developmental Delay, Intellectual Disability, and Cerebellar Hypoplasia Kanca, O; Andrews, JC; Lee, PT et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2019.06.014 (2019)

A Monte Carlo model for organ dose reconstruction of patients in Pencil Beam Scanning (PBS) proton therapy for epidemiologic studies of late effects Yeom, YS; Kuzmin, G; Griffin, KT et al. J Radiol Prot, DOI://10.1088/1361-6498/ab437d (2019)
NMR characterization of rearranged staurosporine aglycone analogues from the marine sponge Damiria sp Tran, TD; Cartner, LK; Bokesch, HR et al. Magn Reson Chem, DOI://10.1002/mrc.4932 (2019)
The Spodoptera frugiperda Sf9 cell line is a heterogeneous population of rhabdovirus-infected and virus-negative cells: Isolation and characterization of cell clones containing rhabdovirus X-gene variants and virus-negative cell clones Ma, H; Nandakumar, S; Bae, EH; Chin, PJ; Khan, AS; Virology, DOI://10.1016/j.virol.2019.08.001 (2019)
Genome-wide DNA methylation analysis of colorectal adenomas with and without recurrence reveals an association between cytosine-phosphate-guanine methylation and histological subtypes Fiedler, D; Hirsch, D; El Hajj, N et al. Genes Chromosomes Cancer, DOI://10.1002/gcc.22787 (2019)
The Structural Basis of the Farnesylated and Methylated KRas4B Interaction with Calmodulin Jang, H; Banerjee, A; Marcus, K et al. Structure, DOI://10.1016/j.str.2019.08.009 (2019)
Imaging the spontaneous flow of thought: Distinct periods of cognition contribute to dynamic functional connectivity during rest Gonzalez-Castillo, J; Caballero-Gaudes, C; Topolski, N; Handwerker, DA; Pereira, F; Bandettini, PA; Neuroimage, DOI://10.1016/j.neuroimage.2019.116129 (2019)

Papillomavirus can be transmitted through the blood and produce infections in blood recipients: Evidence from two animal models Cladel, NM; Jiang, P; Li, JJ et al. Emerg Microbes Infect, DOI://10.1080/22221751.2019.1637072 (2019)
Cysteinyl-tRNA Synthetase Mutations Cause a Multi-System, Recessive Disease That Includes Microcephaly, Developmental Delay, and Brittle Hair and Nails Kuo, ME; Theil, AF; Kievit, A et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2019.01.006 (2019)
Sex differences in the associations of placental epigenetic aging with fetal growth Tekola-Ayele, F; Workalemahu, T; Gorfu, G et al. Aging (Albany NY), DOI://10.18632/aging.102124 (2019)
Genome-wide association study for proliferative diabetic retinopathy in Africans Liu, C; Chen, G; Bentley, AR et al. NPJ Genom Med, DOI://10.1038/s41525-019-0094-7 (2019)
Cohesin Impedes Heterochromatin Assembly in Fission Yeast Cells Lacking Pds5 Folco, HD; McCue, A; Balachandran, V; Grewal, SIS; Genetics, DOI://10.1534/genetics.119.302256 (2019)
T-Cell Deletion of MyD88 Connects IL17 and IκBζ to RAS Oncogenesis Cataisson, C; Salcedo, R; Michalowski, AM et al. Mol. Cancer Res., DOI://10.1158/1541-7786.MCR-19-0227 (2019)

Novel pathogenic COX20 variants causing dysarthria, ataxia, and sensory neuropathy Otero, MG; Tiongson, E; Diaz, F et al. Ann Clin Transl Neurol, DOI://10.1002/acn3.661 (2019)
Glucocorticoid receptor quaternary structure drives chromatin occupancy and transcriptional outcome Paakinaho, V; Johnson, TA; Presman, DM; Hager, GL; Genome Res., DOI://10.1101/gr.244814.118 (2019)
Modulation of Target Antigen Density Improves CAR T-cell Functionality and Persistence Ramakrishna, S; Highfill, SL; Walsh, Z et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-3784 (2019)
Pathogenic TERT promoter variants in telomere diseases Gutierrez-Rodrigues, F; Donaires, FS; Pinto, A et al. Genet. Med., DOI://10.1038/s41436-018-0385-x (2019)
Epigenetic aging is accelerated in alcohol use disorder and regulated by genetic variation in APOL2 Luo, A; Jung, J; Longley, M et al. Neuropsychopharmacology, DOI://10.1038/s41386-019-0500-y (2019)
Relationship of DNA methylation to mutational changes and transcriptional organization in fusion-positive and fusion-negative rhabdomyosarcoma Sun, W; Chatterjee, B; Shern, JF et al. Int. J. Cancer, DOI://10.1002/ijc.32006 (2019)

Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel Yin, Y; Le, SC; Hsu, AL; Borgnia, MJ; Yang, H; Lee, SY; Science, DOI://10.1126/science.aav9334 (2019)
Genomic analyses in African populations identify novel risk loci for cleft palate Butali, A; Mossey, PA; Adeyemo, WL et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddy402 (2019)
Laboratory mice born to wild mice have natural microbiota and model human immune responses Rosshart, SP; Herz, J; Vassallo, BG et al. Science, DOI://10.1126/science.aaw4361 (2019)
T cell stemness and dysfunction in tumors are triggered by a common mechanism Vodnala, SK; Eil, R; Kishton, RJ et al. Science, DOI://10.1126/science.aau0135 (2019)
Dynamical modeling of multi-scale variability in neuronal competition Cohen, BP; Chow, CC; Vattikuti, S; Commun Biol, DOI://10.1038/s42003-019-0555-7 (2019)
Organ-specific dose coefficients derived from Monte Carlo simulations for historical (1930s to 1960s) fluoroscopic and radiographic examinations of tuberculosis patients Borrego, D; Apostoaei, AI; Thomas, BA et al. J Radiol Prot, DOI://10.1088/1361-6498/ab2f10 (2019)

Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis Lam, KG; Brick, K; Cheng, G; Pratto, F; Camerini-Otero, RD; Nat Commun, DOI://10.1038/s41467-019-11820-7 (2019)
The bZIP mutant CEBPB (V285A) has sequence specific DNA binding propensities similar to CREB1 Ray, S; Ufot, A; Assad, N et al. Biochim Biophys Acta Gene Regul Mech, DOI://10.1016/j.bbagrm.2019.02.002 (2019)
Novel age-associated DNA methylation changes and epigenetic age acceleration in middle-aged African Americans and whites Tajuddin, SM; Hernandez, DG; Chen, BH et al. Clin Epigenetics, DOI://10.1186/s13148-019-0722-1 (2019)
Resting-state connectivity of the bed nucleus of the stria terminalis and the central nucleus of the amygdala in clinical anxiet Torrisi, S; Alvarez, GM; Gorka, AX et al. J Psychiatry Neurosci, DOI://10.1503/jpn.180150 (2019)
Insights into pediatric rhabdomyosarcoma research: Challenges and goals Yohe, ME; Heske, CM; Stewart, E et al. Pediatr Blood Cancer, DOI://10.1002/pbc.27869 (2019)
Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel Yin, Y; Wu, M; Hsu, AL et al. Nat Commun, DOI://10.1038/s41467-019-11733-5 (2019)

TET-Catalyzed 5-Carboxylcytosine Promotes CTCF Binding to Suboptimal Sequences Genome-wide Nanan, KK; Sturgill, DM; Prigge, MF et al. iScience, DOI://10.1016/j.isci.2019.07.041 (2019)
Transcriptome signature of cellular senescence Casella, G; Munk, R; Kim, KM et al. Nucleic Acids Res., DOI://10.1093/nar/gkz555 (2019)
Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual Krebs, SJ; Kwon, YD; Schramm, CA et al. Immunity, DOI://10.1016/j.immuni.2019.02.008 (2019)
Large-Scale Communication in the Human Brain Is Rhythmically Modulated through Alpha Coherence Chapeton, JI; Haque, R; Wittig, JH; Inati, SK; Zaghloul, KA; Curr. Biol., DOI://10.1016/j.cub.2019.07.014 (2019)
Transcriptional Bursting and Co-bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility Stavreva, DA; Garcia, DA; Fettweis, G et al. Mol. Cell, DOI://10.1016/j.molcel.2019.06.042 (2019)
Pathogenic variants in the AFG3L2 proteolytic domain cause SCA28 through haploinsufficiency and proteostatic stress-driven OMA1 activation Tulli, S; Del Bondio, A; Baderna, V et al. J. Med. Genet., DOI://10.1136/jmedgenet-2018-105766 (2019)

Histone methyltransferase PRDM9 is not essential for meiosis in male mice Mihola, O; Pratto, F; Brick, K et al. Genome Res., DOI://10.1101/gr.244426.118 (2019)
CRISPR/Cas9-mediated Knockout and In Situ Inversion of ORF57 Gene from All Copies of The KSHV Genome in BCBL-1 Cells BeltCappellino, A; Majerciak, V; Lobanov, A; Lack, J; Cam, M; Zheng, ZM; J. Virol., DOI://10.1128/JVI.00628-19 (2019)
Kilquist syndrome: A novel syndromic hearing loss disorder caused by homozygous deletion of SLC12A2 Macnamara, EF; Koehler, AE; D'Souza, P et al. Hum. Mutat., DOI://10.1002/humu.23722 (2019)
3' Uridylation Confers miRNAs with Non-canonical Target Repertoires Yang, A; Bofill-De Ros, X; Shao, TJ et al. Mol. Cell, DOI://10.1016/j.molcel.2019.05.014 (2019)
Pilot Trial of Adoptive Transfer of Chimeric Antigen Receptor-transduced T Cells Targeting EGFRvIII in Patients With Glioblastoma Goff, SL; Morgan, RA; Yang, JC et al. J. Immunother., DOI://10.1097/CJI.0000000000000260 (2019)
Assignment of virus and antimicrobial resistance genes to microbial hosts in a complex microbial community by combined long-read assembly and proximity ligation Bickhart, DM; Watson, M; Koren, S et al. Genome Biol., DOI://10.1186/s13059-019-1760-x (2019)

Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells Lee, PH; Yamamoto, TN; Gurusamy, D et al. J. Exp. Med., DOI://10.1084/jem.20181218 (2019)
Accurate circular consensus long-read sequencing improves variant detection and assembly of a human genome Wenger, AM; Peluso, P; Rowell, WJ et al. Nat. Biotechnol., DOI://10.1038/s41587-019-0217-9 (2019)
Transcriptome profiling of Plasmodium vivax in Saimiri monkeys identifies potential ligands for invasion Gunalan, K; Sá, JM; Moraes Barros, RR et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1818485116 (2019)
Fully automated patellofemoral MRI segmentation using holistically nested networks: Implications for evaluating patellofemoral osteoarthritis, pain, injury, pathology, and adolescent development Cheng, R; Alexandridi, NA; Smith, RM et al. Magn Reson Med, DOI://10.1002/mrm.27920 (2019)
Distinctions among real and apparent respiratory motions in human fMRI data Power, JD; Lynch, CJ; Silver, BM; Dubin, MJ; Martin, A; Jones, RM; Neuroimage, DOI://10.1016/j.neuroimage.2019.116041 (2019)
Visual temporal frequency preference shows a distinct cortical architecture using fMRI Chai, Y; Handwerker, DA; Marrett, S et al. Neuroimage, DOI://10.1016/j.neuroimage.2019.04.048 (2019)

The RNA exosome nuclease complex regulates human embryonic stem cell differentiation Belair, C; Sim, S; Kim, KY et al. J. Cell Biol., DOI://10.1083/jcb.201811148 (2019)
Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation Nagashima, H; Mahlakõiv, T; Shih, HY et al. Immunity, DOI://10.1016/j.immuni.2019.06.009 (2019)
GATA-2-deficient mast cells limit IgE-mediated immediate hypersensitivity reactions in human subjects Desai, A; Sowerwine, K; Liu, Y et al. J. Allergy Clin. Immunol., DOI://10.1016/j.jaci.2019.05.007 (2019)
Circulating Lymphangioleiomyomatosis Tumor Cells With Loss of Heterozygosity in the TSC2 Gene Show Increased Aldehyde Dehydrogenase Activity Pacheco-Rodríguez, G; Steagall, WK; Samsel, L et al. Chest, DOI://10.1016/j.chest.2019.03.040 (2019)
A suite of automated sequence analyses reduces the number of candidate deleterious variants and reveals a difference between probands and unaffected siblings Gu, F; Wu, A; Gordon, MG et al. Genet. Med., DOI://10.1038/s41436-019-0434-0 (2019)
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer Lo, W; Parkhurst, M; Robbins, PF et al. Cancer Immunol Res, DOI://10.1158/2326-6066.CIR-18-0686 (2019)
Novel mutations in CLN6 cause late-infantile neuronal ceroid lipofuscinosis without visual impairment in two unrelated patients Chin, JJ; Behnam, B; Davids, M et al. Mol. Genet. Metab., DOI://10.1016/j.ymgme.2018.12.001 (2019)
Tumor-infiltrating human CD4+ regulatory T cells display a distinct TCR repertoire and exhibit tumor and neoantigen reactivity Ahmadzadeh, M; Pasetto, A; Jia, L et al. Sci Immunol, DOI://10.1126/sciimmunol.aao4310 (2019)
Exploring induced pluripotency in human fibroblasts via construction, validation, and application of a gene regulatory network Hamaneh, MB; Yu, YK; PLoS ONE, DOI://10.1371/journal.pone.0220742 (2019)
Multimodal imaging reveals a complex pattern of dysfunction in corticolimbic pathways in major depressive disorder Nugent, AC; Farmer, C; Evans, JW; Snider, SL; Banerjee, D; Zarate, CA; Hum Brain Mapp, DOI://10.1002/hbm.24679 (2019)
An insight into the sialome, mialome and virome of the horn fly, Haematobia irritans Ribeiro, JM; Debat, HJ; Boiani, M; Ures, X; Rocha, S; Breijo, M; BMC Genomics, DOI://10.1186/s12864-019-5984-7 (2019)
Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts Narisu, N; Rothwell, R; Vrtačnik, P et al. Aging Cell, DOI://10.1111/acel.13010 (2019)

Structures and operating principles of the replisome Gao, Y; Cui, Y; Fox, T et al. Science, DOI://10.1126/science.aav7003 (2019)
Race-ethnic differences in the associations of maternal lipid trait genetic risk scores with longitudinal fetal growth Ouidir, M; Mendola, P; Workalemahu, T et al. J Clin Lipidol, DOI://10.1016/j.jacl.2019.06.007 (2019)
The seizure onset zone drives state-dependent epileptiform activity in susceptible brain regions Diamond, JM; Chapeton, JI; Theodore, WH; Inati, SK; Zaghloul, KA; Clin Neurophysiol, DOI://10.1016/j.clinph.2019.05.032 (2019)
Immune regulation by glucocorticoids can be linked to cell type-dependent transcriptional responses Franco, LM; Gadkari, M; Howe, KN et al. J. Exp. Med., DOI://10.1084/jem.20180595 (2019)
Subtle predictive movements reveal actions regardless of social context McMahon, EG; Zheng, CY; Pereira, F; Gonzalez, R; Ungerleider, LG; Vaziri-Pashkam, M; J Vis, DOI://10.1167/19.7.16 (2019)
The Magnitude of IFN-γ Responses Is Fine-Tuned by DNA Architecture and the Non-coding Transcript of Ifng-as1 Petermann, F; Pękowska, A; Johnson, CA et al. Mol. Cell, DOI://10.1016/j.molcel.2019.06.025 (2019)

Pseudodominance of autoinflammatory disease in a single Turkish family explained by co-inheritance of haploinsufficiency of A20 and familial Mediterranean fever Horita, N; Gül, A; Aksentijevich, I; Kastner, D; Remmers, EF; Clin. Exp. Rheumatol., 0392-856X (2019)
Engineered Bcor mutations lead to acute leukemia of progenitor B-1 lymphocyte origin in a sensitized background Yin, M; Chung, YJ; Lindsley, RC et al. Blood, DOI://10.1182/blood.2018864173 (2019)
Discovering new antiretroviral compounds in Big Data chemical space of the SAVI library Savosina, PI; Stolbov, LA; Druzhilovskiy, DS; Filimonov, DA; Nicklaus, MC; Poroikov, VV; Biomed Khim, DOI://10.18097/PBMC20196502073 (2019)
Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers Parkhurst, MR; Robbins, PF; Tran, E et al. Cancer Discov, DOI://10.1158/2159-8290.CD-18-1494 (2019)
Eye in a Disk: eyeIntegration Human Pan-Eye and Body Transcriptome Database Version 1.0 Swamy, V; McGaughey, D; Invest. Ophthalmol. Vis. Sci., DOI://10.1167/iovs.19-27106 (2019)
The transcription factor TCF-1 enforces commitment to the innate lymphoid cell lineage Harly, C; Kenney, D; Ren, G et al. Nat. Immunol., DOI://10.1038/s41590-019-0445-7 (2019)

Mapping associations between polygenic risks for childhood neuropsychiatric disorders, symptoms of attention deficit hyperactivity disorder, cognition, and the brain Sudre, G; Frederick, J; Sharp, W et al. Mol. Psychiatry, DOI://10.1038/s41380-019-0350-3 (2019)
Evidence for the interaction of A3 adenosine receptor agonists at the drug-binding site (s) of Human P-glycoprotein (ABCB1) Abel, B; Tosh, DK; Durell, SR et al. Mol. Pharmacol., DOI://10.1124/mol.118.115295 (2019)
Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization Kong, R; Duan, H; Sheng, Z et al. Cell, DOI://10.1016/j.cell.2019.06.030 (2019)
Association Between Reduced Brain Glucose Metabolism and Cortical Thickness in Alcoholics: Evidence of Neurotoxicity Tomasi, DG; Wiers, CE; Shokri-Kojori, E et al. Int. J. Neuropsychopharmacol., DOI://10.1093/ijnp/pyz036 (2019)
Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition Chuang, GY; Zhou, J; Acharya, P et al. Structure, DOI://10.1016/j.str.2018.10.007 (2019)
A role for the CD38 rs3796863 polymorphism in alcohol and monetary reward: evidence from CD38 knockout mice and alcohol self-administration, [11C]-raclopride binding, and functional MRI in humans Lee, MR; Shin, JH; Deschaine, S et al. Am J Drug Alcohol Abuse, DOI://10.1080/00952990.2019.1638928 (2019)
Maternal dyslipidemia during early pregnancy and epigenetic ageing of the placenta Shrestha, D; Workalemahu, T; Tekola-Ayele, F; Epigenetics, DOI://10.1080/15592294.2019.1629234 (2019)
Spatial control of oxygen delivery to three-dimensional cultures alters cancer cell growth and gene expression Wulftange, WJ; Rose, MA; Garmendia-Cedillos, M et al. J. Cell. Physiol., DOI://10.1002/jcp.28665 (2019)
RNA-seq analysis of the salivary glands and midgut of the Argasid tick Ornithodoros rostratus Araujo, RN; Silva, NCS; Mendes-Sousa, A et al. Sci Rep, DOI://10.1038/s41598-019-42899-z (2019)
Learning deep similarity metric for 3D MR-TRUS image registration Haskins, G; Kruecker, J; Kruger, U et al. Int J Comput Assist Radiol Surg, DOI://10.1007/s11548-018-1875-7 (2019)
Blood DNA methylation and breast cancer risk: a meta-analysis of four prospective cohort studies Bodelon, C; Ambatipudi, S; Dugué, PA et al. Breast Cancer Res., DOI://10.1186/s13058-019-1145-9 (2019)
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure Sung, YJ; de Las Fuentes, L; Winkler, TW et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddz070 (2019)

Molecular recognition of nucleosomes by binding partners Kale, S; Goncearenco, A; Markov, Y; Landsman, D; Panchenko, AR; Curr. Opin. Struct. Biol., DOI://10.1016/j.sbi.2019.03.010 (2019)
Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity Canela, A; Maman, Y; Huang, SN et al. Mol. Cell, DOI://10.1016/j.molcel.2019.04.030 (2019)
RNA Sequencing in B-Cell Lymphomas Huang, DW; Dawood, M; Johnson, CA; Schmitz, R; Methods Mol. Biol., DOI://10.1007/978-1-4939-9151-8_13 (2019)
Meta-analysis of GWA studies provides new insights on the genetic architecture of skin pigmentation in recently admixed populations Lona-Durazo, F; Hernandez-Pacheco, N; Fan, S et al. BMC Genet., DOI://10.1186/s12863-019-0765-5 (2019)
Hair of the Dog: Identification of a Cis-Regulatory Module Predicted to Influence Canine Coat Composition Whitaker, DT; Ostrander, EA; Genes (Basel), DOI://10.3390/genes10050323 (2019)
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity Kilpeläinen, TO; Bentley, AR; Noordam, R et al. Nat Commun, DOI://10.1038/s41467-018-08008-w (2019)
RNA-Seq and protein mass spectrometry in microdissected kidney tubules reveal signaling processes initiating lithium-induced nephrogenic diabetes insipidus Sung, CC; Chen, L; Limbutara, K et al. Kidney Int., DOI://10.1016/j.kint.2019.02.015 (2019)
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions de Vries, PS; Brown, MR; Bentley, AR et al. Am. J. Epidemiol., DOI://10.1093/aje/kwz005 (2019)
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids Bentley, AR; Sung, YJ; Brown, MR et al. Nat. Genet., DOI://10.1038/s41588-019-0378-y (2019)
Developments in integrative modeling with dynamical interfaces Ozdemir, ES; Nussinov, R; Gursoy, A; Keskin, O; Curr. Opin. Struct. Biol., DOI://10.1016/j.sbi.2018.10.007 (2019)
Multiplicative fitness, rapid haplotype discovery, and fitness decay explain evolution of human MHC Lobkovsky, AE; Levi, L; Wolf, YI et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1714436116 (2019)
Correction: Single cell analysis of adult mouse skeletal muscle stem cells in homeostatic and regenerative conditions (doi: 10.1242/dev.174177) Dell'Orso, S; Juan, AH; Ko, KD et al. Development, DOI://10.1242/dev.181743 (2019)

Sexual dimorphisms in the transcriptomes of murine salivary glands Mukaibo, T; Gao, X; Yang, NY; Oei, MS; Nakamoto, T; Melvin, JE; FEBS Open Bio, DOI://10.1002/2211-5463.12625 (2019)
ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response Adeyemo, AA; Zaghloul, NA; Chen, G et al. Nat Commun, DOI://10.1038/s41467-019-10967-7 (2019)
Structural Insights into α-Synuclein Fibril Polymorphism: Effects of Parkinson's Disease-Related C-Terminal Truncations Ni, X; McGlinchey, RP; Jiang, J; Lee, JC; J. Mol. Biol., DOI://10.1016/j.jmb.2019.07.001 (2019)
The ribosomal prolyl-hydroxylase OGFOD1 decreases during cardiac differentiation and modulates translation and splicing Stoehr, A; Kennedy, L; Yang, Y et al. JCI Insight, DOI://10.1172/jci.insight.128496 (2019)
PTM-Logo: a program for generation of sequence logos based on position-specific background amino-acid probabilities Saethang, T; Hodge, K; Yang, CR et al. Bioinformatics, DOI://10.1093/bioinformatics/btz568 (2019)
Phosphoproteomic Identification of Vasopressin V2 Receptor-Dependent Signaling in the Renal Collecting Duct Deshpande, V; Kao, AR; Raghuram, V; Datta, A; Chou, CL; Knepper, MA; Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00281.2019 (2019)
Correction: Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression Guo, W; Machado-Vieira, R; Mathew, S et al. Transl Psychiatry, DOI://10.1038/s41398-019-0442-5 (2019)
Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis Deniset, JF; Belke, D; Lee, WY et al. Immunity, DOI://10.1016/j.immuni.2019.06.010 (2019)
Pathogenic Autoreactive T and B Cells Cross-React with Mimotopes Expressed by a Common Human Gut Commensal to Trigger Autoimmunity Ruff, WE; Dehner, C; Kim, WJ et al. Cell Host Microbe, DOI://10.1016/j.chom.2019.05.003 (2019)
Functional interplay between DEAD-box RNA helicases Ded1 and Dbp1 in preinitiation complex attachment and scanning on structured mRNAs in vivo Sen, ND; Gupta, N; K Archer, S; Preiss, T; Lorsch, JR; Hinnebusch, AG; Nucleic Acids Res., DOI://10.1093/nar/gkz595 (2019)
Parsing neurodevelopmental features of irritability and anxiety: Replication and validation of a latent variable approach Cardinale, EM; Kircanski, K; Brooks, J et al. Dev. Psychopathol., DOI://10.1017/S095457941900035X (2019)
Chemical genomics reveals histone deacetylases are required for core regulatory transcription Gryder, BE; Wu, L; Woldemichael, GM et al. Nat Commun, DOI://10.1038/s41467-019-11046-7 (2019)

Avapritinib: A Selective Inhibitor of KIT and PDGFRα that Reverses ABCB1 and ABCG2-Mediated Multidrug Resistance in Cancer Cell Lines Wu, CP; Lusvarghi, S; Wang, JC et al. Mol. Pharm., DOI://10.1021/acs.molpharmaceut.9b00274 (2019)
BORIS expression in ovarian cancer precursor cells alters the CTCF cistrome and enhances invasiveness through GALNT14 Hillman, JC; Pugacheva, EM; Barger, CJ et al. Mol. Cancer Res., DOI://10.1158/1541-7786.MCR-19-0310 (2019)
Cancer-testis antigens as biomarkers for Merkel cell carcinoma: Pitfalls and opportunities Dasgeb, B; Mehregan, D; Ring, C; Nartker, N; Brownell, I; J. Cutan. Pathol., DOI://10.1111/cup.13528 (2019)
The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons Seah, MKY; Wang, Y; Goy, PA et al. Development, DOI://10.1242/dev.170266 (2019)
Maternal Exposure to Non-nutritive Sweeteners Impacts Progeny's Metabolism and Microbiome Olivier-Van Stichelen, S; Rother, KI; Hanover, JA; Front Microbiol, DOI://10.3389/fmicb.2019.01360 (2019)
Plerixafor for the Treatment of WHIM Syndrome McDermott, DH; Pastrana, DV; Calvo, KR et al. N. Engl. J. Med., DOI://10.1056/NEJMoa1808575 (2019)
Impact of APOL1 Genetic Variants on HIV-1 Infection and Disease Progression An, P; Kirk, GD; Limou, S; Binns-Roemer, E; Kopp, JB; Winkler, CA; Front Immunol, DOI://10.3389/fimmu.2019.00053 (2019)
Amino-acid inserts of HIV-1 capsid (CA) induce CA degradation and abrogate viral infectivity: Insights for the dynamics and mechanisms of HIV-1 CA decomposition Amano, M; Bulut, H; Tamiya, S; Nakamura, T; Koh, Y; Mitsuya, H; Sci Rep, DOI://10.1038/s41598-019-46082-2 (2019)
Cholesterol-Dependent Bending Energy Is Important in Cholesterol Distribution of the Plasma Membrane Allender, DW; Sodt, AJ; Schick, M; Biophys. J., DOI://10.1016/j.bpj.2019.03.028 (2019)
Effects of Ketamine on Brain Activity During Emotional Processing: Differential Findings in Depressed Versus Healthy Control Participants Reed, JL; Nugent, AC; Furey, ML; Szczepanik, JE; Evans, JW; Zarate, CA; Biol Psychiatry Cogn Neurosci Neuroimaging, DOI://10.1016/j.bpsc.2019.01.005 (2019)
Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection Yao, C; Sun, HW; Lacey, NE et al. Nat. Immunol., DOI://10.1038/s41590-019-0403-4 (2019)
Novel Heterozygous Variants in KMT2D Associated with Holoprosencephaly Tekendo-Ngongang, C; Kruszka, P; Martinez, AF; Muenke, M; Clin. Genet., DOI://10.1111/cge.13598 (2019)

Deep neural network predicts emotional responses of the human brain from functional magnetic resonance imaging Kim, HC; Bandettini, PA; Lee, JH; Neuroimage, DOI://10.1016/j.neuroimage.2018.10.054 (2019)
A critical review of five machine learning-based algorithms for predicting protein stability changes upon mutation Fang, J Brief. Bioinformatics, DOI://10.1093/bib/bbz071 (2019)
A Genome-Wide Epstein-Barr Virus Polyadenylation Map and Its Antisense RNA to EBNA Majerciak, V; Yang, W; Zheng, J; Zhu, J; Zheng, ZM; J. Virol., DOI://10.1128/JVI.01593-18 (2019)
Interactions of Water and Alkanes: Modifying Additive Force Fields to Account for Polarization Effects Krämer, A; Pickard, FC; Huang, J et al. J Chem Theory Comput, DOI://10.1021/acs.jctc.9b00016 (2019)
CPF Recruitment to Non-canonical Transcription Termination Sites Triggers Heterochromatin Assembly and Gene Silencing Vo, TV; Dhakshnamoorthy, J; Larkin, M et al. Cell Rep, DOI://10.1016/j.celrep.2019.05.107 (2019)
Author Correction: Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis Vogt, EJ; Tokuhiro, K; Guo, M et al. Nat Commun, DOI://10.1038/s41467-019-10935-1 (2019)

The structure-activity profile of mercaptobenzamides' anti-HIV activity suggests that thermodynamics of metabolism is more important than binding affinity to the target Nikolayevskiy, H; Robello, M; Scerba, MT et al. Eur J Med Chem, DOI://10.1016/j.ejmech.2019.06.020 (2019)
Large-scale purification of functional human P-glycoprotein (ABCB1) Nandigama, K; Lusvarghi, S; Shukla, S; Ambudkar, SV; Protein Expr. Purif., DOI://10.1016/j.pep.2019.03.002 (2019)
De novo assembly of the goldfish (Carassius auratus) genome and the evolution of genes after whole-genome duplication Chen, Z; Omori, Y; Koren, S et al. Sci Adv, DOI://10.1126/sciadv.aav0547 (2019)
Molecular dissection of cone photoreceptor-enriched genes encoding transmembrane and secretory proteins Papal, S; Monti, CE; Tennison, ME; Swaroop, A; J. Neurosci. Res., DOI://10.1002/jnr.24329 (2019)
Transposable element insertions in fission yeast drive adaptation to environmental stress Esnault, C; Lee, M; Ham, C; Levin, HL; Genome Res., DOI://10.1101/gr.239699.118 (2019)
The splicing factor U2AF1 contributes to cancer progression through a noncanonical role in translation regulation Palangat, M; Anastasakis, DG; Fei, DL et al. Genes Dev., DOI://10.1101/gad.319590.118 (2019)

RASA2 and NF1; two-negative regulators of Ras with complementary functions in melanoma Arafeh, R; Di Pizio, A; Elkahloun, AG; Dym, O; Niv, MY; Samuels, Y; Oncogene, DOI://10.1038/s41388-018-0578-4 (2019)
Maternal BMI-Increasing Genetic Risk Score and Fetal Weights among Diverse US Ethnic Groups Shrestha, D; Rahman, ML; Hinkle, SN; Workalemahu, T; Tekola-Ayele, F; Obesity (Silver Spring), DOI://10.1002/oby.22499 (2019)
Author Correction: Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration Ratnapriya, R; Sosina, OA; Starostik, MR et al. Nat. Genet., DOI://10.1038/s41588-019-0430-y (2019)
Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP Li, M; Wang, Y; Banerjee, R et al. Elife, DOI://10.7554/eLife.47060 (2019)
Induced Chromosomal Aneuploidy Results in Global and Consistent Deregulation of the Transcriptome of Cancer Cells Wangsa, D; Braun, R; Stuelten, CH et al. Neoplasia, DOI://10.1016/j.neo.2019.04.009 (2019)
Sodium valproate rescues expression of TRANK1 in iPSC-derived neural cells that carry a genetic variant associated with serious mental illness Jiang, X; Detera-Wadleigh, SD; Akula, N et al. Mol. Psychiatry, DOI://10.1038/s41380-018-0207-1 (2019)

Deep learning-based muscle segmentation and quantification at abdominal CT: application to a longitudinal adult screening cohort for sarcopenia assessment Graffy, PM; Liu, J; Pickhardt, PJ; Burns, JE; Yao, J; Summers, RM; Br J Radiol, DOI://10.1259/bjr.20190327 (2019)
A parameterized digital 3D model of the Rhesus macaque face for investigating the visual processing of social cues Murphy, AP; Leopold, DA; J. Neurosci. Methods, DOI://10.1016/j.jneumeth.2019.06.001 (2019)
Association of Step Volume and Intensity With All-Cause Mortality in Older Women Lee, IM; Shiroma, EJ; Kamada, M; Bassett, DR; Matthews, CE; Buring, JE; JAMA Intern Med, DOI://10.1001/jamainternmed.2019.0899 (2019)
Small posterior fossa in Chiari I malformation affected families is significantly linked to 1q43-44 and 12q23-24.11 using whole exome sequencing Musolf, AM; Ho, WSC; Long, KA et al. Eur. J. Hum. Genet., DOI://10.1038/s41431-019-0457-7 (2019)
Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals Noordam, R; Young, WJ; Salman, R et al. J. Am. Coll. Cardiol., DOI://10.1016/j.jacc.2019.03.519 (2019)
The Impact of Anthelmintic Treatment on Human Gut Microbiota Based on Cross-Sectional and Pre- and Postdeworming Comparisons in Western Kenya Easton, AV; Quiñones, M; Vujkovic-Cvijin, I et al. MBio, DOI://10.1128/mBio.00519-19 (2019)

Novel Inter-omic Analysis Reveals Relationships Between Diverse Gut Microbiota and Host Immune Dysregulation in HLA-B27-Induced Experimental Spondyloarthritis Gill, T; Brooks, SR; Rosenbaum, JT; Asquith, M; Colbert, RA; , DOI://10.1002/art.41018 (2019)
Agouti-Related Protein 2 Is a New Player in the Teleost Stress Response System Shainer, I; Michel, M; Marquart, GD et al. Curr. Biol., DOI://10.1016/j.cub.2019.05.021 (2019)
Aberrant expression of select piRNA-pathway genes does not reactivate piRNA silencing in cancer cells Genzor, P; Cordts, SC; Bokil, NV; Haase, AD; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1904498116 (2019)
Disordered RNA chaperones can enhance nucleic acid folding via local charge screening Holmstrom, ED; Liu, Z; Nettels, D; Best, RB; Schuler, B; Nat Commun, DOI://10.1038/s41467-019-10356-0 (2019)
Long-Range RNA Structural Information via a Paramagnetically Tagged Reporter Protein Strickland, M; Catazaro, J; Rajasekaran, R et al. J. Am. Chem. Soc., DOI://10.1021/jacs.8b11384 (2019)
Lysosomal Storage and Albinism Due to Effects of a De Novo CLCN7 Variant on Lysosomal Acidification Nicoli, ER; Weston, MR; Hackbarth, M et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2019.04.008 (2019)

Aicardi-Goutières syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast cancer Deasy, SK; Uehara, R; Vodnala, SK et al. PLoS Genet., DOI://10.1371/journal.pgen.1008020 (2019)
One-carbon metabolism gene polymorphisms are associated with cognitive trajectory among African-American adults Beydoun, MA; Tajuddin, SM; Shaked, D; Beydoun, HA; Evans, MK; Zonderman, AB; Neurobiol. Aging, DOI://10.1016/j.neurobiolaging.2019.05.013 (2019)
Structural Basis of p97 Inhibition by the Site-Selective Anticancer Compound CB-5083 Tang, WK; Odzorig, T; Jin, W; Xia, D; Mol. Pharmacol., DOI://10.1124/mol.118.114256 (2019)
Fully automated prostate whole gland and central gland segmentation on MRI using holistically nested networks with short connections Cheng, R; Lay, N; Roth, HR et al. J Med Imaging (Bellingham), DOI://10.1117/1.JMI.6.2.024007 (2019)
Correlation between Disease Severity and the Intestinal Microbiome in Mycobacterium tuberculosis-Infected Rhesus Macaques Namasivayam, S; Kauffman, KD; McCulloch, JA et al. MBio, DOI://10.1128/mBio.01018-19 (2019)
Smartphone Level Test Measures Disability in Several Neurological Domains for Patients With Multiple Sclerosis Boukhvalova, AK; Fan, O; Weideman, AM et al. Front Neurol, DOI://10.3389/fneur.2019.00358 (2019)

Integrating multiple biomarkers to increase sensitivity for the detection of Onchocerca volvulus infection Bennuru, S; Oduro-Boateng, G; Osigwe, C et al. J. Infect. Dis., DOI://10.1093/infdis/jiz307 (2019)
Neutrophil Subsets, Platelets, and Vascular Disease in Psoriasis Teague, HL; Varghese, NJ; Tsoi, LC et al. JACC Basic Transl Sci, DOI://10.1016/j.jacbts.2018.10.008 (2019)
Efficacy of different dynamic functional connectivity methods to capture cognitively relevant information Xie, H; Zheng, CY; Handwerker, DA et al. Neuroimage, DOI://10.1016/j.neuroimage.2018.12.037 (2019)
TPMCalculator: one-step software to quantify mRNA abundance of genomic features Vera Alvarez, R; Pongor, LS; Mariño-Ramírez, L; Landsman, D; Bioinformatics, DOI://10.1093/bioinformatics/bty896 (2019)
The structural basis for Ras activation of PI3Kα lipid kinase Zhang, M; Jang, H; Nussinov, R; Phys Chem Chem Phys, DOI://10.1039/c9cp00101h (2019)
A chromosome-scale assembly of the major African malaria vector Anopheles funestus Ghurye, J; Koren, S; Small, ST et al. Gigascience, DOI://10.1093/gigascience/giz063 (2019)

Extensive Heterogeneity and Intrinsic Variation in Spatial Genome Organization Finn, EH; Pegoraro, G; Brandão, HB et al. Cell, DOI://10.1016/j.cell.2019.01.020 (2019)
Methylphenidate's effects on thalamic metabolism and functional connectivity in cannabis abusers and healthy controls Demiral, ŞB; Tomasi, D; Wiers, CE et al. Neuropsychopharmacology, DOI://10.1038/s41386-018-0287-2 (2019)
Neighbourhood disadvantage and depressive symptoms among adolescents followed into emerging adulthood Goldstein, RB; Lee, AK; Haynie, DL et al. J Epidemiol Community Health, DOI://10.1136/jech-2018-212004 (2019)
Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes Zubcevic, L; Hsu, AL; Borgnia, MJ; Lee, SY; Elife, DOI://10.7554/eLife.45779 (2019)
Methods for Discovering and Targeting Druggable Protein-Protein Interfaces and Their Application to Repurposing Ozdemir, ES; Halakou, F; Nussinov, R; Gursoy, A; Keskin, O; Methods Mol. Biol., DOI://10.1007/978-1-4939-8955-3_1 (2019)
The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription Malik, N; Yan, H; Moshkovich, N et al. Nat Commun, DOI://10.1038/s41467-019-10102-6 (2019)

Remarkable Rigidity of the Single α-Helical Domain of Myosin-VI As Revealed by NMR Spectroscopy Barnes, CA; Shen, Y; Ying, J et al. J. Am. Chem. Soc., DOI://10.1021/jacs.9b03116 (2019)
An integrative Bayesian approach to matrix-based analysis in neuroimaging Chen, G; Bürkner, PC; Taylor, PA et al. Hum Brain Mapp, DOI://10.1002/hbm.24686 (2019)
Crystal Structure of Bacterial Cytochrome bc1 in Complex with Azoxystrobin Reveals a Conformation Switch of the Rieske Iron-Sulfur Protein Subunit Esser, L; Zhou, F; Yu, CA; Xia, D; J. Biol. Chem., DOI://10.1074/jbc.RA119.008381 (2019)
Aberrant Clonal Hematopoiesis following Lentiviral Vector Transduction of HSPCs in a Rhesus Macaque Espinoza, DA; Fan, X; Yang, D et al. Mol. Ther., DOI://10.1016/j.ymthe.2019.04.003 (2019)
Mechanisms of Calcium Leak from Cardiac Sarcoplasmic Reticulum Revealed by Statistical Mechanics Maltsev, AV; Stern, MD; Maltsev, VA; Biophys. J., DOI://10.1016/j.bpj.2019.04.031 (2019)
REC114 Partner ANKRD31 Controls Number, Timing, and Location of Meiotic DNA Breaks Boekhout, M; Karasu, ME; Wang, J et al. Mol. Cell, DOI://10.1016/j.molcel.2019.03.023 (2019)
Mucosal vaccine efficacy against intrarectal SHIV is independent of anti-Env antibody response Sui, Y; Lewis, GK; Wang, Y et al. J. Clin. Invest., DOI://10.1172/JCI122110 (2019)
Layer-specific activation of sensory input and predictive feedback in the human primary somatosensory cortex Yu, Y; Huber, L; Yang, J et al. Sci Adv, DOI://10.1126/sciadv.aav9053 (2019)
Opportunistic Osteoporosis Screening at Routine Abdominal and Thoracic CT: Normative L1 Trabecular Attenuation Values in More than 20 000 Adults Jang, S; Graffy, PM; Ziemlewicz, TJ; Lee, SJ; Summers, RM; Pickhardt, PJ; Radiology, DOI://10.1148/radiol.2019181648 (2019)
Regulatory switch at the cytoplasmic interface controls TRPV channel gating Zubcevic, L; Borschel, WF; Hsu, AL; Borgnia, MJ; Lee, SY; Elife, DOI://10.7554/eLife.47746 (2019)
Biallelic HEPHL1 variants impair ferroxidase activity and cause an abnormal hair phenotype Sharma, P; Reichert, M; Lu, Y et al. PLoS Genet., DOI://10.1371/journal.pgen.1008143 (2019)
Heterogeneity in refractory acute myeloid leukemia Horibata, S; Gui, G; Lack, J; DeStefano, CB; Gottesman, MM; Hourigan, CS; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1902375116 (2019)

The relapsing fever spirochete Borrelia turicatae persists in the highly oxidative environment of its soft-bodied tick vector Bourret, TJ; Boyle, WK; Zalud, AK; Valenzuela, JG; Oliveira, F; Lopez, JE; Cell. Microbiol., DOI://10.1111/cmi.12987 (2019)
The skin transcriptome in hidradenitis suppurativa uncovers an antimicrobial and sweat gland gene signature which has distinct overlap with wounded skin Coates, M; Mariottoni, P; Corcoran, DL et al. PLoS ONE, DOI://10.1371/journal.pone.0216249 (2019)
Atomic resolution cryo-EM structure of a native-like CENP-A nucleosome aided by an antibody fragment Zhou, BR; Yadav, KNS; Borgnia, M et al. Nat Commun, DOI://10.1038/s41467-019-10247-4 (2019)
A Suite of Therapeutically-Inspired Nucleic Acid Logic Systems for Conditional Generation of Single-Stranded and Double-Stranded Oligonucleotides Zakrevsky, P; Bindewald, E; Humbertson, H; Viard, M; Dorjsuren, N; Shapiro, BA; Nanomaterials (Basel), DOI://10.3390/nano9040615 (2019)
XL-DNase-seq: improved footprinting of dynamic transcription factors Oh, KS; Ha, J; Baek, S; Sung, MH; Epigenetics Chromatin, DOI://10.1186/s13072-019-0277-6 (2019)
Potential Regulatory Role of Competitive Encounter Complexes in Paralogous Phosphotransferase Systems Strickland, M; Kale, S; Strub, MP et al. J. Mol. Biol., DOI://10.1016/j.jmb.2019.04.040 (2019)

Apparent diffusion coefficient changes in human brain during sleep - Does it inform on the existence of a glymphatic system Demiral, ŞB; Tomasi, D; Sarlls, J et al. Neuroimage, DOI://10.1016/j.neuroimage.2018.10.043 (2019)
Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium Kobayashi, T; Voisin, B; Kim, DY et al. Cell, DOI://10.1016/j.cell.2018.12.031 (2019)
Artificial intelligence at the intersection of pathology and radiology in prostate cancer Harmon, SA; Tuncer, S; Sanford, T; Choyke, PL; Türkbey, B; Diagn Interv Radiol, DOI://10.5152/dir.2019.19125 (2019)
Neocortical Projection Neurons Instruct Inhibitory Interneuron Circuit Development in a Lineage-Dependent Manner Wester, JC; Mahadevan, V; Rhodes, CT et al. Neuron, DOI://10.1016/j.neuron.2019.03.036 (2019)
The oral microbiome of patients undergoing treatment for severe aplastic anemia: a pilot study Ames, NJ; Barb, JJ; Ranucci, A et al. Ann. Hematol., DOI://10.1007/s00277-019-03599-w (2019)
eNetXplorer: an R package for the quantitative exploration of elastic net families for generalized linear models Candia, J; Tsang, JS; BMC Bioinformatics, DOI://10.1186/s12859-019-2778-5 (2019)

Nucleosome spacing periodically modulates nucleosome chain folding and DNA topology in circular nucleosome arrays Bass, MV; Nikitina, T; Norouzi, D; Zhurkin, VB; Grigoryev, SA; J. Biol. Chem., DOI://10.1074/jbc.RA118.006412 (2019)
The Transcriptome of the Salivary Glands of Amblyomma aureolatum Reveals the Antimicrobial Peptide Microplusin as an Important Factor for the Tick Protection Against Rickettsia rickettsii Infection Martins, LA; Malossi, CD; Galletti, MFBM et al. Front Physiol, DOI://10.3389/fphys.2019.00529 (2019)
TFE3 Xp11.2 Translocation Renal Cell Carcinoma Mouse Model Reveals Novel Therapeutic Targets and Identifies GPNMB as a Diagnostic Marker for Human Disease Baba, M; Furuya, M; Motoshima, T et al. Mol. Cancer Res., DOI://10.1158/1541-7786.MCR-18-1235 (2019)
Whole-Genome Sequences of Salmonella enterica Serovar I 4,[5],12:i:- Isolates from Swine Gonzalez, S; Harvey, RB; Scott, HM et al. Microbiol Resour Announc, DOI://10.1128/MRA.00223-19 (2019)
A Frizzled-Like Cysteine-Rich Domain in Glypican-3 Mediates Wnt Binding and Regulates Hepatocellular Carcinoma Tumor Growth in Mice Li, N; Wei, L; Liu, X et al. Hepatology, DOI://10.1002/hep.30646 (2019)
Maternal and Offspring Genetic Risk of Type 2 Diabetes and Offspring Birthweight Among African Ancestry Populations Rahman, ML; Shrestha, D; Workalemahu, T et al. J. Clin. Endocrinol. Metab., DOI://10.1210/jc.2018-02756 (2019)

Equitable Thresholding and Clustering (ETAC): A novel method for FMRI clustering in AFNI Cox, RW Brain Connect, DOI://10.1089/brain.2019.0666 (2019)
Evaluating corrections for Eddy-currents and other EPI distortions in diffusion MRI: methodology and a dataset for benchmarking Irfanoglu, MO; Sarlls, J; Nayak, A; Pierpaoli, C; Magn Reson Med, DOI://10.1002/mrm.27577 (2019)
Banana (Musa acuminata) transcriptome profiling in response to rhizobacteria: Bacillus amyloliquefaciens Bs006 and Pseudomonas fluorescens Ps006 Gamez, RM; Rodríguez, F; Vidal, NM et al. BMC Genomics, DOI://10.1186/s12864-019-5763-5 (2019)
Data-driven inference of hidden nodes in networks Hoang, DT; Jo, J; Periwal, V; Phys Rev E, DOI://10.1103/PhysRevE.99.042114 (2019)
Identifying Small Proteins by Ribosome Profiling with Stalled Initiation Complexes Weaver, J; Mohammad, F; Buskirk, AR; Storz, G; MBio, DOI://10.1128/mBio.02819-18 (2019)
Epigenetic regulation of REX1 expression and chromatin binding specificity by HMGNs Zhang, S; Deng, T; Tang, W et al. Nucleic Acids Res., DOI://10.1093/nar/gkz161 (2019)

Early-childhood social reticence predicts SCR-BOLD coupling during fear extinction recall in preadolescent youth Michalska, KJ; Feldman, JS; Ivie, EJ et al. Dev Cogn Neurosci, DOI://10.1016/j.dcn.2018.12.003 (2019)
miR-155 harnesses Phf19 to potentiate cancer immunotherapy through epigenetic reprogramming of CD8+ T cell fate Ji, Y; Fioravanti, J; Zhu, W et al. Nat Commun, DOI://10.1038/s41467-019-09882-8 (2019)
Physical Activity Patterns and Mortality: The Weekend Warrior and Activity Bouts Shiroma, EJ; Lee, IM; Schepps, MA; Kamada, M; Harris, TB; Med Sci Sports Exerc, DOI://10.1249/MSS.0000000000001762 (2019)
Defective IgA response to atypical intestinal commensals in IL-21 receptor deficiency reshapes immune cell homeostasis and mucosal immunity Cho, H; Jaime, H; de Oliveira, RP et al. Mucosal Immunol, DOI://10.1038/s41385-018-0056-x (2019)
Heritability and genetic variance of dementia with Lewy bodies Guerreiro, R; Escott-Price, V; Hernandez, DG et al. Neurobiol. Dis., DOI://10.1016/j.nbd.2019.04.004 (2019)
Differential Brain Mechanisms of Selection and Maintenance of Information during Working Memory Quentin, R; King, JR; Sallard, E et al. J. Neurosci., DOI://10.1523/JNEUROSCI.2764-18.2019 (2019)
High dimensional mediation analysis with latent variables Derkach, A; Pfeiffer, RM; Chen, TH; Sampson, JN; Biometrics, DOI://10.1111/biom.13053 (2019)
Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting Cheng, C; Xu, K; Kong, R et al. PLoS ONE, DOI://10.1371/journal.pone.0215163 (2019)
Integrated Genomic and Functional microRNA Analysis Identifies miR-30-5p as a Tumor Suppressor and Potential Therapeutic Nanomedicine in Head and Neck Cancer Saleh, AD; Cheng, H; Martin, SE et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-0716 (2019)
Computation-guided analysis of paroxetine binding to hSERT reveals functionally important structural elements and dynamics Abramyan, AM; Slack, RD; Meena, S et al. Neuropharmacology, DOI://10.1016/j.neuropharm.2018.10.040 (2019)
Frontal alpha asymmetry moderates the relations between behavioral inhibition and social-effect ERN Harrewijn, A; Buzzell, GA; Debnath, R; Leibenluft, E; Pine, DS; Fox, NA; Biol Psychol, DOI://10.1016/j.biopsycho.2018.12.014 (2019)
Characterization of the Phosphorylation Site of GRTH/DDX25 and Protein Kinase A Binding Interface Provides Structural Basis for the Design of a Non-Hormonal Male Contraceptive Raju, M; Hassan, SA; Kavarthapu, R; Anbazhagan, R; Dufau, ML; Sci Rep, DOI://10.1038/s41598-019-42857-9 (2019)
Identification of Neoantigen-Reactive Tumor-Infiltrating Lymphocytes in Primary Bladder Cancer Leko, V; McDuffie, LA; Zheng, Z et al. J. Immunol., DOI://10.4049/jimmunol.1801022 (2019)
Assessing the Role of 98 Established Loci for BMI in American Indians Muller, YL; Hanson, RL; Piaggi, P et al. Obesity (Silver Spring), DOI://10.1002/oby.22433 (2019)
A Rapid Form of Offline Consolidation in Skill Learning Bönstrup, M; Iturrate, I; Thompson, R; Cruciani, G; Censor, N; Cohen, LG; Curr. Biol., DOI://10.1016/j.cub.2019.02.049 (2019)
Whole genome sequencing of canids reveals genomic regions under selection and variants influencing morphology Plassais, J; Kim, J; Davis, BW et al. Nat Commun, DOI://10.1038/s41467-019-09373-w (2019)
Molecular constraints on CDR3 for thymic selection of MHC-restricted TCRs from a random pre-selection repertoire Lu, J; Van Laethem, F; Bhattacharya, A et al. Nat Commun, DOI://10.1038/s41467-019-08906-7 (2019)
An African-specific haplotype in MRGPRX4 is associated with menthol cigarette smoking Kozlitina, J; Risso, D; Lansu, K et al. PLoS Genet., DOI://10.1371/journal.pgen.1007916 (2019)

Evolution of All-Atom Protein Force Fields to Improve Local and Global Properties Zerze, GH; Zheng, W; Best, RB; Mittal, J; J Phys Chem Lett, DOI://10.1021/acs.jpclett.9b00850 (2019)
The mechanism of PI3Kα activation at the atomic level Zhang, M; Jang, H; Nussinov, R; Chem Sci, DOI://10.1039/c8sc04498h (2019)
Design and in Vivo Characterization of A1 Adenosine Receptor Agonists in the Native Ribose and Conformationally Constrained (N)-Methanocarba Series Tosh, DK; Rao, H; Bitant, A et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.8b01662 (2019)
Association Between Childhood Anhedonia and Alterations in Large-Scale Resting-State Networks and Task-Evoked Activation Pornpattananangkul, N; Leibenluft, E; Pine, DS; Stringaris, A; JAMA Psychiatry, DOI://10.1001/jamapsychiatry.2019.0020 (2019)
SOX2 Epidermal Overexpression Promotes Cutaneous Wound Healing via Activation of EGFR/MEK/ERK Signaling Mediated by EGFR Ligands Uchiyama, A; Nayak, S; Graf, R et al. J. Invest. Dermatol., DOI://10.1016/j.jid.2019.02.004 (2019)
APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors Roper, N; Gao, S; Maity, TK et al. Cell Rep, DOI://10.1016/j.celrep.2019.02.028 (2019)
Cases from the Undiagnosed Diseases Network: The continued value of counseling skills in a new genomic era Macnamara, EF; Schoch, K; Kelley, EG et al. J Genet Couns, DOI://10.1002/jgc4.1091 (2019)
Automated segmentation and quantification of aortic calcification at abdominal CT: application of a deep learning-based algorithm to a longitudinal screening cohort Graffy, PM; Liu, J; O'Connor, S; Summers, RM; Pickhardt, PJ; Abdom Radiol (NY), DOI://10.1007/s00261-019-02014-2 (2019)
Improvement of antibody functionality by structure-guided paratope engraftment Liu, Q; Lai, YT; Zhang, P et al. Nat Commun, DOI://10.1038/s41467-019-08658-4 (2019)
A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex Marabelli, C; Marrocco, B; Pilotto, S et al. Cell Rep, DOI://10.1016/j.celrep.2019.03.061 (2019)
Halogen bond interactions of novel HIV-1 protease inhibitors (PI)(GRL-001-15 and GRL-003-15) with the flap of protease are critical for their potent activity against wild-type and multi-PI-resistant HIV-1 variants Hattori, SI; Hayashi, H; Bulut, H et al. Antimicrob. Agents Chemother., DOI://10.1128/AAC.02635-18 (2019)
Local unfolding of the HSP27 monomer regulates chaperone activity Alderson, TR; Roche, J; Gastall, HY et al. Nat Commun, DOI://10.1038/s41467-019-08557-8 (2019)

Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7 Lo, YH; Sobhany, M; Hsu, AL et al. Nat Commun, DOI://10.1038/s41467-019-08373-0 (2019)
Absolute risks of cervical precancer among women who fulfill exiting guidelines based on HPV and cytology cotesting Landy, R; Schiffman, M; Sasieni, PD et al. Int. J. Cancer, DOI://10.1002/ijc.32268 (2019)
Decoding the 5' nucleotide bias of PIWI-interacting RNAs Stein, CB; Genzor, P; Mitra, S et al. Nat Commun, DOI://10.1038/s41467-019-08803-z (2019)
Parkinson's disease age at onset genome-wide association study: Defining heritability, genetic loci, and α-synuclein mechanisms Blauwendraat, C; Heilbron, K; Vallerga, CL et al. Mov. Disord., DOI://10.1002/mds.27659 (2019)
Inference for case-control studies with incident and prevalent cases Maziarz, M; Liu, Y; Qin, J; Pfeiffer, RM; Biometrics, DOI://10.1111/biom.13023 (2019)
Human Influenza A Virus Hemagglutinin Glycan Evolution Follows a Temporal Pattern to a Glycan Limit Altman, MO; Angel, M; Košík, I et al. MBio, DOI://10.1128/mBio.00204-19 (2019)
Network inference in stochastic systems from neurons to currencies: Improved performance at small sample size Hoang, DT; Song, J; Periwal, V; Jo, J; Phys Rev E, DOI://10.1103/PhysRevE.99.023311 (2019)
Shared genetic underpinnings of childhood obesity and adult cardiometabolic diseases Tekola-Ayele, F; Lee, A; Workalemahu, T; Sánchez-Pozos, K; Hum. Genomics, DOI://10.1186/s40246-019-0202-x (2019)
Human-Origin Influenza A (H3N2) Reassortant Viruses in Swine, Southeast Mexico Nelson, MI; Souza, CK; Trovão, NS et al. Emerging Infect. Dis., DOI://10.3201/eid2504.180779 (2019)
Posture-dependent dose coefficients of mesh-type ICRP reference computational phantoms for photon external exposures Yeom, YS; Han, H; Choi, C et al. Phys Med Biol, DOI://10.1088/1361-6560/ab0917 (2019)
Revisiting Volumes of Lipid Components in Bilayers Nagle, JF; Venable, RM; Maroclo-Kemmerling, E; Tristram-Nagle, S; Harper, PE; Pastor, RW; J Phys Chem B, DOI://10.1021/acs.jpcb.8b12010 (2019)
Synaptic potentiation and rapid antidepressant response to ketamine in treatment-resistant major depression: A replication study Nugent, AC; Wills, KE; Gilbert, JR; Zarate, CA; Psychiatry Res Neuroimaging, DOI://10.1016/j.pscychresns.2018.09.001 (2019)

Biophysical mechanisms in the mammalian respiratory oscillator re-examined with a new data-driven computational model Phillips, RS; John, TT; Koizumi, H; Molkov, YI; Smith, JC; Elife, DOI://10.7554/eLife.41555 (2019)
A Bayesian hierarchical logistic regression model of multiple informant family health histories Lin, J; Myers, MF; Koehly, LM; Marcum, CS; BMC Med Res Methodol, DOI://10.1186/s12874-019-0700-5 (2019)
Automated Computational Detection, Quantitation, and Mapping of Mitosis in Whole-Slide Images for Clinically Actionable Surgical Pathology Decision Support Puri, M; Hoover, SB; Hewitt, SM et al. J Pathol Inform, DOI://10.4103/jpi.jpi_59_18 (2019)
Control and Regulation of Substrate Selection in Cytoplasmic and Mitochondrial Catabolic Networks. A Systems Biology Analysis Cortassa, S; Aon, MA; Sollott, SJ; Front Physiol, DOI://10.3389/fphys.2019.00201 (2019)
Contrasting roles of the RSC and ISW1/CHD1 chromatin remodelers in RNA polymerase II elongation and termination Ocampo, J; Chereji, RV; Eriksson, PR; Clark, DJ; Genome Res., DOI://10.1101/gr.242032.118 (2019)
The zinc-finger protein CLAMP promotes gypsy chromatin insulator function in Drosophila Bag, I; Dale, RK; Palmer, C; Lei, EP; J. Cell. Sci., DOI://10.1242/jcs.226092 (2019)
Brain Mechanisms of Attention Orienting Following Frustration: Associations With Irritability and Age in Youths Tseng, WL; Deveney, CM; Stoddard, J et al. Am J Psychiatry, DOI://10.1176/appi.ajp.2018.18040491 (2019)
Single-cell chromatin immunocleavage sequencing (scChIC-seq) to profile histone modification Ku, WL; Nakamura, K; Gao, W et al. Nat. Methods, DOI://10.1038/s41592-019-0361-7 (2019)
Rapid and reversible suppression of ALT by DAXX in osteosarcoma cells Yost, KE; Clatterbuck Soper, SF; Walker, RL et al. Sci Rep, DOI://10.1038/s41598-019-41058-8 (2019)
Subset testing and analysis of multiple phenotypes Derkach, A; Pfeiffer, RM; Genet. Epidemiol., DOI://10.1002/gepi.22199 (2019)
CMCdG, a Novel Nucleoside Analog with Favorable Safety Features, Exerts Potent Activity against Wild-Type and Entecavir-Resistant Hepatitis B Virus Higashi-Kuwata, N; Hayashi, S; Das, D et al. Antimicrob. Agents Chemother., DOI://10.1128/AAC.02143-18 (2019)
Semi-Automated 3D Segmentation of Human Skeletal Muscle Using Focused Ion Beam-Scanning Electron Microscopic Images Caffrey, B; Maltsev, AV; Gonzalez-Freire, M; Hartnell, LM; Ferrucci, L; Subramaniam, S; J. Struct. Biol., DOI://10.1016/j.jsb.2019.03.008 (2019)
Representation and relative abundance of cell-type selective markers in whole-kidney RNA-Seq data Clark, JZ; Chen, L; Chou, CL; Jung, HJ; Lee, JW; Knepper, MA; Kidney Int., DOI://10.1016/j.kint.2018.11.028 (2019)
Activity and structural analysis of GRL-117C: a novel small molecule CCR5 inhibitor active against R5-tropic HIV-1s Nakata, H; Maeda, K; Das, D et al. Sci Rep, DOI://10.1038/s41598-019-41080-w (2019)
Cloning and characterization of a novel aspartate/glutamate racemase from the acorn worm Saccoglossus kowalevskii Uda, K; Ishizuka, N; Edashige, Y; Kikuchi, A; Radkov, AD; Moe, LA; Comp. Biochem. Physiol. B, Biochem. Mol. Biol., DOI://10.1016/j.cbpb.2019.03.006 (2019)
Inactivating Mutation in IRF8 Promotes Osteoclast Transcriptional Programs and Increases Susceptibility to Tooth Root Resorption Thumbigere-Math, V; Foster, BL; Bachu, M et al. J. Bone Miner. Res., DOI://10.1002/jbmr.3690 (2019)
S Values for neuroimaging procedures on Korean pediatric and adult head computational phantoms Villoing, D; Lee, AK; Choi, HD; Lee, C; Radiat Prot Dosimetry, DOI://10.1093/rpd/ncy287 (2019)
Population-based opportunistic osteoporosis screening: Validation of a fully automated CT tool for assessing longitudinal BMD changes Pickhardt, PJ; Lee, SJ; Liu, J et al. Br J Radiol, DOI://10.1259/bjr.20180726 (2019)

Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine Tekola-Ayele, F; Lee, A; Workalemahu, T et al. Sci Rep, DOI://10.1038/s41598-019-40834-w (2019)
Accounting for random observation time in risk prediction with longitudinal markers: An imputation approach Han, Y; Liu, D; Stat Methods Med Res, DOI://10.1177/0962280219833089 (2019)
Genomic deletions upstream of lamin B1 lead to atypical autosomal dominant leukodystrophy Nmezi, B; Giorgio, E; Raininko, R et al. Neurol Genet, DOI://10.1212/NXG.0000000000000305 (2019)
NELFE-Dependent MYC Signature Identifies a Unique Cancer Subtype in Hepatocellular Carcinoma Dang, H; Pomyen, Y; Martin, SP et al. Sci Rep, DOI://10.1038/s41598-019-39727-9 (2019)
Synthesis and evaluation of two new candidate high-affinity full agonist PET radioligands for imaging 5-HT1B receptors Lindberg, A; Lu, S; Nag, S et al. Nucl. Med. Biol., DOI://10.1016/j.nucmedbio.2019.01.005 (2019)
An insight into the sialotranscriptome and virome of Amazonian anophelines Scarpassa, VM; Debat, HJ; Alencar, RB et al. BMC Genomics, DOI://10.1186/s12864-019-5545-0 (2019)
Phosphorylation Changes in Response to Kinase Inhibitor H89 in PKA-Null Cells Limbutara, K; Kelleher, A; Yang, CR; Raghuram, V; Knepper, MA; Sci Rep, DOI://10.1038/s41598-019-39116-2 (2019)
Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase Anderson, CJ; Baird, MR; Hsu, A et al. Cell Rep, DOI://10.1016/j.celrep.2019.01.058 (2019)
DiscoverSL: an R package for multi-omic data driven prediction of synthetic lethality in cancers Das, S; Deng, X; Camphausen, K; Shankavaram, U; Bioinformatics, DOI://10.1093/bioinformatics/bty673 (2019)
Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting Chauhan, G; Adams, HHH; Satizabal, CL et al. Neurology, DOI://10.1212/WNL.0000000000006851 (2019)
Isothermal Titration Calorimetry of Be2+ with Phosphatidylserine Models Guides All-Atom Force-Field Development for LipidIon Interactions Leonard, AN; Klauda, JB; Sukharev, S; J Phys Chem B, DOI://10.1021/acs.jpcb.8b11884 (2019)
The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity Gautam, S; Fioravanti, J; Zhu, W et al. Nat. Immunol., DOI://10.1038/s41590-018-0311-z (2019)
Dosimetric Impact of a New Computational Voxel Phantom Series for the Japanese Atomic Bomb Survivors: Children and Adults Griffin, K; Paulbeck, C; Bolch, W et al. Radiat. Res., DOI://10.1667/RR15267.1 (2019)
Nanovesicles Versus Nanoparticle-Supported Lipid Bilayers: Massive Differences in Bilayer Structures and in Diffusivities of Lipid Molecules and Nanoconfined Water Jing, H; Wang, Y; Desai, PR; Ramamurthi, KS; Das, S; Langmuir, DOI://10.1021/acs.langmuir.8b03805 (2019)
ComPaSS-GWAS: A method to reduce type I error in genome-wide association studies when replication data are not available Sabourin, JA; Cropp, CD; Sung, H; Brody, LC; Bailey-Wilson, JE; Wilson, AF; Genet. Epidemiol., DOI://10.1002/gepi.22168 (2019)
Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses Kanekiyo, M; Joyce, MG; Gillespie, RA et al. Nat. Immunol., DOI://10.1038/s41590-018-0305-x (2019)
Spatial Attention Deficits Are Causally Linked to an Area in Macaque Temporal Cortex Bogadhi, AR; Bollimunta, A; Leopold, DA; Krauzlis, RJ; Curr. Biol., DOI://10.1016/j.cub.2019.01.028 (2019)
Memory T cells targeting oncogenic mutations detected in peripheral blood of epithelial cancer patients Cafri, G; Yossef, R; Pasetto, A et al. Nat Commun, DOI://10.1038/s41467-019-08304-z (2019)

Gustatory responses in macaque monkeys revealed with fMRI: Comments on taste, taste preference, and internal state Kaskan, PM; Dean, AM; Nicholas, MA; Mitz, AR; Murray, EA; Neuroimage, DOI://10.1016/j.neuroimage.2018.10.005 (2019)
Structural Differences between Pri-miRNA Paralogs Promote Alternative Drosha Cleavage and Expand Target Repertoires Bofill-De Ros, X; Kasprzak, WK; Bhandari, Y et al. Cell Rep, DOI://10.1016/j.celrep.2018.12.054 (2019)
Simultaneous targeting of linked loci in mouse embryos using base editing Lee, HK; Willi, M; Smith, HE et al. Sci Rep, DOI://10.1038/s41598-018-33533-5 (2019)
Molecular Dynamics Simulations of Membrane Permeability Venable, RM; Krämer, A; Pastor, RW; Chem. Rev., DOI://10.1021/acs.chemrev.8b00486 (2019)
Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration Ratnapriya, R; Sosina, OA; Starostik, MR et al. Nat. Genet., DOI://10.1038/s41588-019-0351-9 (2019)
Exome genotyping and linkage analysis identifies two novel linked regions and replicates two others for myopia in Ashkenazi Jewish families Simpson, CL; Musolf, AM; Li, Q et al. BMC Med. Genet., DOI://10.1186/s12881-019-0752-8 (2019)

Brain-wide cellular resolution imaging of Cre transgenic zebrafish lines for functional circuit-mapping Tabor, KM; Marquart, GD; Hurt, C et al. Elife, DOI://10.7554/eLife.42687 (2019)
Interpretation of spectroscopic data using molecular simulations for the secondary active transporter BetP Leone, V; Waclawska, I; Kossmann, K et al. J. Gen. Physiol., DOI://10.1085/jgp.201812111 (2019)
Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis Bandres-Ciga, S; Noyce, AJ; Hemani, G et al. Ann. Neurol., DOI://10.1002/ana.25431 (2019)
Whole Transcriptome Analysis of Renal Intercalated Cells Predicts Lipopolysaccharide Mediated Inhibition of Retinoid X Receptor alpha Function Saxena, V; Fitch, J; Ketz, J et al. Sci Rep, DOI://10.1038/s41598-018-36921-z (2019)
High Quality ATAC-Seq Data Recovered from Cryopreserved Breast Cell Lines and Tissue Fujiwara, S; Baek, S; Varticovski, L; Kim, S; Hager, GL; Sci Rep, DOI://10.1038/s41598-018-36927-7 (2019)
Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ewing Sarcoma: Role in Tumor Growth and Immune Evasion Heitzeneder, S; Sotillo, E; Shern, JF et al. J. Natl. Cancer Inst., DOI://10.1093/jnci/djy209 (2019)
The FLT3 inhibitor midostaurin selectively resensitizes ABCB1-overexpressing multidrug-resistant cancer cells to conventional chemotherapeutic agents Hsiao, SH; Lusvarghi, S; Huang, YH; Ambudkar, SV; Hsu, SC; Wu, CP; Cancer Lett., DOI://10.1016/j.canlet.2019.01.001 (2019)
Antimicrobial Chrysophaentin Analogs Identified from Laboratory Cultures of the Marine Microalga Chrysophaeum taylorii Davison, JR; Bewley, CA; J. Nat. Prod., DOI://10.1021/acs.jnatprod.8b00858 (2019)
Distinct Clinical and Pathological Features of Melorheostosis Associated With Somatic MAP2K1 Mutations Jha, S; Fratzl-Zelman, N; Roschger, P et al. J. Bone Miner. Res., DOI://10.1002/jbmr.3577 (2019)
The prevalence of germline DICER1 pathogenic variation in cancer populations Kim, J; Schultz, KAP; Hill, DA; Stewart, DR; Mol Genet Genomic Med, DOI://10.1002/mgg3.555 (2019)
Sequence Variation Associated with SLC12A5 Gene Expression Is Linked to Brain Structure and Function in Healthy Adults Gregory, MD; Kippenhan, JS; Callicott, JH et al. Cereb. Cortex, DOI://10.1093/cercor/bhy344 (2019)
Interleukin-12 receptor β2 from grass carp: Molecular characterization and its involvement in Aeromonas hydrophila-induced intestinal inflammation Song, XH; Tang, J; Gao, TT et al. Fish Shellfish Immunol., DOI://10.1016/j.fsi.2019.01.016 (2019)

Structure and function of an ectopic Polycomb chromatin domain De, S; Cheng, Y; Sun, MA; Gehred, ND; Kassis, JA; Sci Adv, DOI://10.1126/sciadv.aau9739 (2019)
A conserved dimer interface connects ERH and YTH family proteins to promote gene silencing Xie, G; Vo, TV; Thillainadesan, G et al. Nat Commun, DOI://10.1038/s41467-018-08273-9 (2019)
Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Epigenomic Program to Reduce Allergic Pathology Schwartz, DM; Farley, TK; Richoz, N et al. Immunity, DOI://10.1016/j.immuni.2018.12.014 (2019)
The Emergence and Functional Fitness of Memory CD4+ T Cells Require the Transcription Factor Thpok Ciucci, T; Vacchio, MS; Gao, Y et al. Immunity, DOI://10.1016/j.immuni.2018.12.019 (2019)
Next-Generation Sequencing to Diagnose Suspected Genetic Disorders Adams, DR; Eng, CM; N. Engl. J. Med., DOI://10.1056/NEJMc1814955 (2019)
Effect of amino acids on transcription and translation of key genes in E. coli K and B grown at a steady state in minimal medium Baez, A; Kumar, A; Sharma, AK; Anderson, ED; Shiloach, J; N Biotechnol, DOI://10.1016/j.nbt.2018.10.004 (2019)

The mitochondrial type IB topoisomerase drives mitochondrial translation and carcinogenesis Baechler, SA; Factor, VM; Dalla Rosa, I et al. Nat Commun, DOI://10.1038/s41467-018-07922-3 (2019)
Secondary Metabolites from the Fungus Dictyosporium sp. and Their MALT1 Inhibitory Activities Tran, TD; Wilson, BAP; Henrich, CJ et al. J. Nat. Prod., DOI://10.1021/acs.jnatprod.8b00871 (2019)
The phenotypic landscape of a Tbc1d24 mutant mouse includes convulsive seizures resembling human early infantile epileptic encephalopathy Tona, R; Chen, W; Nakano, Y et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddy445 (2019)
Hydrogen-bond dependent conformational switching: a computational challenge from experimental thermochemistry Luccarelli, J; Paton, RS; J. Org. Chem., DOI://10.1021/acs.joc.8b02436 (2019)
Early infantile-onset epileptic encephalopathy 28 due to a homozygous microdeletion involving the WWOX gene in a region of uniparental disomy Davids, M; Markello, T; Wolfe, LA et al. Hum. Mutat., DOI://10.1002/humu.23675 (2019)
A versatile mouse model of epitope-tagged histone H3.3 to study epigenome dynamics Bachu, M; Tamura, T; Chen, C et al. J. Biol. Chem., DOI://10.1074/jbc.RA118.005550 (2019)

Genetic analysis of neurodegenerative diseases in a pathology cohort Blauwendraat C, Pletnikova O, Geiger, JT et al Neurobiology of Aging, 10.1016/j.neurobiolaging.2018.11.007 (2019)
Conformational stability and dynamics of the cancer-associated isoform δ133p53β are modulated by p53 peptides and p53-specific DNA Lei, J; Qi, R; Tang, Y et al. FASEB J., DOI://10.1096/fj.201801973R (2019)
hnRNP L-dependent protection of normal mRNAs from NMD subverts quality control in B cell lymphoma Kishor, A; Ge, Z; Hogg, JR; EMBO J., DOI://10.15252/embj.201899128 (2019)
Linear mixed models for association analysis of quantitative traits with next-generation sequencing data Chiu, CY; Yuan, F; Zhang, BS et al. Genet. Epidemiol., DOI://10.1002/gepi.22177 (2019)
Structural Characterization of Biomolecules through Atomistic Simulations Guided by DEER Measurements Marinelli, F; Fiorin, G; Structure, DOI://10.1016/j.str.2018.10.013 (2019)
Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury Harrison, OJ; Linehan, JL; Shih, HY et al. Science, DOI://10.1126/science.aat6280 (2019)
Mosaic Y loss is moderately associated with solid tumor risk Loftfield, E; Zhou, W; Yeager, M; Chanock, SJ; Freedman, ND; Machiela, MJ; Cancer Res., DOI://10.1158/0008-5472.CAN-18-2566 (2019)
Targeted deletion of an NRL- and CRX-regulated alternative promoter specifically silences FERM and PDZ domain containing 1 (Frmpd1) in rod photoreceptors Campla, CK; Mast, H; Dong, L et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddy388 (2019)
Practical issues in using generalized estimating equations for inference on transitions in longitudinal data: What is being estimated Bible, J; Albert, PS; Simons-Morton, BG; Liu, D; Stat Med, DOI://10.1002/sim.8014 (2019)
Integrated Epigenetic Mapping of Human and Mouse Salivary Gene Regulation Michael, DG; Pranzatelli, TJF; Warner, BM; Yin, H; Chiorini, JA; J. Dent. Res., DOI://10.1177/0022034518806518 (2019)
Organ Dose Estimation accounting for uncertainty for pediatric and young adult CT scans in the United Kingdom Lee, C; Journy, N; Moroz, BE et al. Radiat Prot Dosimetry, DOI://10.1093/rpd/ncy184 (2019)
Optimizing and evaluating biomarker combinations as trial-level general surrogates Gabriel, EE; Sachs, MC; Daniels, MJ; Halloran, ME; Stat Med, DOI://10.1002/sim.7996 (2019)

Interface-Based Structural Prediction of Novel Host-Pathogen Interactions Guven-Maiorov, E; Tsai, CJ; Ma, B; Nussinov, R; Methods Mol. Biol., DOI://10.1007/978-1-4939-8736-8_18 (2019)
QuagmiR: A Cloud-based Application for IsomiR Big Data Analytics Bofill-De Ros, X; Chen, K; Chen, S et al. Bioinformatics, DOI://10.1093/bioinformatics/bty843 (2019)
Early life disadvantage and adult adiposity: tests of sensitive periods during childhood and behavioural mediation in adulthood Gilman, SE; Huang, YT; Jimenez, MP et al. Int J Epidemiol, DOI://10.1093/ije/dyy199 (2019)
A Bayesian multi-dimensional couple-based latent risk model with an application to infertility Hwang, BS; Chen, Z; Louis, GMB; Albert, PS; Biometrics, DOI://10.1111/biom.12972 (2019)
Half blind superiority tests for clinical trials of anti-infective drugs Follmann, D; Brittain, E; Lumbard, K; Stat Med, DOI://10.1002/sim.7954 (2019)
Time-varying whole-brain functional network connectivity coupled to task engagement Xie H, Gonzalez-Castillo J, Handwerker D, Bandettini P Network Neuro Science, doi://10.1162/netn_a_00051 (2019)

Neurophysiological Changes Associated with Antidepressant Response to Ketamine Not Observed in a Negative Trial of Scopolamine in Major Depressive Disorder Park, L; Furey, M; Nugent, AC et al. Int. J. Neuropsychopharmacol., DOI://10.1093/ijnp/pyy051 (2019)
Targeted RNA-sequencing for the quantification of measurable residual disease in acute myeloid leukemia Dillon, LW; Hayati, S; Roloff, GW et al. Haematologica, DOI://10.3324/haematol.2018.203133 (2019)
Whole Blood Gene Expression Associated with Clinical Biological Age Lin, H; Lunetta, KL; Zhao, Q et al. J. Gerontol. A Biol. Sci. Med. Sci., DOI://10.1093/gerona/gly164 (2019)
Deep-learning-assisted Volume Visualization Cheng, HC; Cardone, A; Jain, S et al. IEEE Trans Vis Comput Graph, DOI://10.1109/TVCG.2018.2796085 (2019)
A feasibility study to reduce misclassification error in occupational dose estimates for epidemiological studies using body size-dependent computational phantoms Sarah Kim, Lienard Chang, Elizabeth Mosher, Choonik Lee, and Choonsik IEEE Transactions on Radiation and Plasma Medical Sciences, 0.1109/TRPMS.2018.2847227 (2019)
Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium Merino, J; Dashti, HS; Li, SX et al. Mol. Psychiatry, DOI://10.1038/s41380-018-0079-4 (2019)

Tightly Integrated Genomic and Epigenomic Data Mining Using Tensor Decomposition Fang, J Bioinformatics, DOI://10.1093/bioinformatics/bty513 (2019)
Mapping the neuroanatomic substrates of cognition in familial attention deficit hyperactivity disorder Muster, R; Choudhury, S; Sharp, W; Kasparek, S; Sudre, G; Shaw, P; Psychol Med, DOI://10.1017/S0033291718001241 (2019)
A joint spatial factor analysis model to accommodate data from misaligned areal units with application to Louisiana social vulnerability Nethery, RC; Sandler, DP; Zhao, S; Engel, LS; Kwok, RK; Biostatistics, DOI://10.1093/biostatistics/kxy016 (2019)
Ketamine has distinct electrophysiological and behavioral effects in depressed and healthy subjects Nugent, AC; Ballard, ED; Gould, TD et al. Mol. Psychiatry, DOI://10.1038/s41380-018-0028-2 (2019)

2018 (494 papers)

An approximate joint model for multiple paired longitudinal outcomes and time-to-event data Elmi, AF; Grantz, KL; Albert, PS; , Biometrics, DOI://10.1111/biom.12862 (2018)
Methylomic profiling and replication implicates deregulation of PCSK9 in alcohol use disorder Lohoff, FW; Sorcher, JL; Rosen, AD et al. Mol. Psychiatry, DOI://10.1038/mp.2017.168 (2018)

Molecular Recognition between Aβ-Specific Single-Domain Antibody and Aβ Misfolded Aggregates Zhang, M; Zheng, J; Nussinov, R; Ma, B; Antibodies (Basel), DOI://10.3390/antib7030025 (2018)
Comment on "Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water" Best, RB; Zheng, W; Borgia, A et al. Science, DOI://10.1126/science.aar7101 (2018)
Discovery of Kaposi's sarcoma herpesvirus-encoded circular RNAs and a human antiviral circular RNA Tagawa, T; Gao, S; Koparde, VN et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1816183115 (2018)
Biallelic mutations in mitochondrial tryptophanyl-tRNA synthetase cause Levodopa-responsive infantile-onset Parkinsonism Burke, EA; Frucht, SJ; Thompson, K et al. Clin. Genet., DOI://10.1111/cge.13172 (2018)
Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures Lee, JS; Adler, L; Karathia, H et al. Cell, DOI://10.1016/j.cell.2018.07.019 (2018)
Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells Bodogai, M; O'Connell, J; Kim, K et al. Sci Transl Med, DOI://10.1126/scitranslmed.aat4271 (2018)

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits Evangelou, E; Warren, HR; Mosen-Ansorena, D et al. Nat. Genet., DOI://10.1038/s41588-018-0205-x (2018)
Fully automated segmentation and quantification of visceral and subcutaneous fat at abdominal CT: application to a longitudinal adult screening cohort Lee, SJ; Liu, J; Yao, J; Kanarek, A; Summers, RM; Pickhardt, PJ; Br J Radiol, DOI://10.1259/bjr.20170968 (2018)
Analysis of type 2 diabetes and obesity genetic variants in Mexican Pima Indians: Marked allelic differentiation among Amerindians at HLA Hsueh, WC; Bennett, PH; Esparza-Romero, J et al. Ann. Hum. Genet., DOI://10.1111/ahg.12252 (2018)
A Recurrent De Novo Heterozygous COG4 Substitution Leads to Saul-Wilson Syndrome, Disrupted Vesicular Trafficking, and Altered Proteoglycan Glycosylation Ferreira, CR; Xia, ZJ; Clément, A et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2018.09.003 (2018)
Reservoir pH replica exchange Damjanovic, A; Miller, BT; Okur, A; Brooks, BR; J Chem Phys, DOI://10.1063/1.5027413 (2018)
Conformational analysis of replica exchange MD: Temperature-dependent Markov networks for FF amyloid peptides Narayan, B; Herbert, C; Yuan, Y; Rodriguez, BJ; Brooks, BR; Buchete, NV; J Chem Phys, DOI://10.1063/1.5027580 (2018)
EXP2 is a nutrient-permeable channel in the vacuolar membrane of Plasmodium and is essential for protein export via PTEX Garten, M; Nasamu, AS; Niles, JC; Zimmerberg, J; Goldberg, DE; Beck, JR; Nat Microbiol, DOI://10.1038/s41564-018-0222-7 (2018)
Non-classical monocytes as mediators of tissue destruction in arthritis Puchner, A; Saferding, V; Bonelli, M et al. Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2018-213250 (2018)
Abruptio placentae risk and genetic variations in mitochondrial biogenesis and oxidative phosphorylation: replication of a candidate gene association study Workalemahu, T; Enquobahrie, DA; Gelaye, B et al. Am. J. Obstet. Gynecol., DOI://10.1016/j.ajog.2018.08.042 (2018)
Activation of Th1 Immunity within the Tumor Microenvironment Is Associated with Clinical Response to Lenalidomide in Chronic Lymphocytic Leukemia Aue, G; Sun, C; Liu, D et al. J. Immunol., DOI://10.4049/jimmunol.1800570 (2018)
Comparison of normal tissue dose calculation methods for epidemiological studies of radiotherapy patients Mille, MM; Jung, JW; Lee, C; Kuzmin, GA; Lee, C; J Radiol Prot, DOI://10.1088/1361-6498/aabd4f (2018)
Novel variants in SPTAN1 without epilepsy: An expansion of the phenotype Gartner, V; Markello, TC; Macnamara, E et al. Am. J. Med. Genet. A, DOI://10.1002/ajmg.a.40628 (2018)

Novel truncating mutation in TENM3 in siblings with motor developmental delay, ocular coloboma, oval cornea, without microphthalmia Stephen, J; Nampoothiri, S; Kuppa, S et al. Am. J. Med. Genet. A, DOI://10.1002/ajmg.a.40658 (2018)
Exogenous ghrelin administration increases alcohol self-administration and modulates brain functional activity in heavy-drinking alcohol-dependent individuals Farokhnia, M; Grodin, EN; Lee, MR et al. Mol. Psychiatry, DOI://10.1038/mp.2017.226 (2018)
Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase Hickman, AB; Voth, AR; Ewis, H; Li, X; Craig, NL; Dyda, F; Nucleic Acids Res., DOI://10.1093/nar/gky838 (2018)
Reprogramming of regulatory network using expression uncovers sex-specific gene regulation in Drosophila Wang, Y; Cho, DY; Lee, H; Fear, J; Oliver, B; Przytycka, TM; Nat Commun, DOI://10.1038/s41467-018-06382-z (2018)
High density lipoprotein proteome is associated with cardiovascular risk factors and atherosclerosis burden as evaluated by coronary CT angiography Gordon, SM; Chung, JH; Playford, MP et al. Atherosclerosis, DOI://10.1016/j.atherosclerosis.2018.09.032 (2018)
Agreement in Histological Assessment of Mitotic Activity Between Microscopy and Digital Whole Slide Images Informs Conversion for Clinical Diagnosis Wei, BR; Halsey, CH; Hoover, SB et al. Acad Pathol, DOI://10.1177/2374289519859841 (2018)
Dynamics of Chromatin Fibers: Comparison of Monte Carlo Simulations with Force Spectroscopy Norouzi, D; Zhurkin, VB; Biophys. J., DOI://10.1016/j.bpj.2018.06.032 (2018)
GCN5L1 interacts with αTAT1 and RanBP2 to regulate hepatic α-tubulin acetylation and lysosome trafficking Wu, K; Wang, L; Chen, Y et al. J. Cell. Sci., DOI://10.1242/jcs.221036 (2018)
Sequential loss of tumor surface antigens following chimeric antigen receptor T-cell therapies in diffuse large B-cell lymphoma Shalabi, H; Kraft, IL; Wang, HW et al. Haematologica, DOI://10.3324/haematol.2017.183459 (2018)
GATA2 deficiency and human hematopoietic development modeled using induced pluripotent stem cells Jung, M; Cordes, S; Zou, J et al. Blood Adv, DOI://10.1182/bloodadvances.2018017137 (2018)
Interdomain Stabilization Impairs CD4 Binding and Improves Immunogenicity of the HIV-1 Envelope Trimer Zhang, P; Gorman, J; Geng, H et al. Cell Host Microbe, DOI://10.1016/j.chom.2018.05.002 (2018)
Genetic variations and risk of placental abruption: A genome-wide association study and meta-analysis of genome-wide association studies Workalemahu, T; Enquobahrie, DA; Gelaye, B et al. Placenta, DOI://10.1016/j.placenta.2018.04.008 (2018)

Role of humoral immunity against hepatitis B virus core antigen in the pathogenesis of acute liver failure Chen, Z; Diaz, G; Pollicino, T et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1809028115 (2018)
Bi-allelic TMEM94 Truncating Variants Are Associated with Neurodevelopmental Delay, Congenital Heart Defects, and Distinct Facial Dysmorphism Stephen, J; Maddirevula, S; Nampoothiri, S et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2018.11.001 (2018)
Using Devices to Assess Physical Activity and Sedentary Behavior in a Large Cohort Study, the Women's Health Study Lee, IM; Shiroma, EJ; Evenson, KR; Kamada, M; LaCroix, AZ; Buring, JE; J Meas Phys Behav, DOI://10.1123/jmpb.2018-0005 (2018)
Co-activation patterns in resting-state fMRI signals Liu, X; Zhang, N; Chang, C; Duyn, JH; Neuroimage, DOI://10.1016/j.neuroimage.2018.01.041 (2018)
Using mobile location data in biomedical research while preserving privacy Goldenholz, DM; Goldenholz, SR; Krishnamurthy, KB et al. J Am Med Inform Assoc, DOI://10.1093/jamia/ocy071 (2018)
Effect of Genetic Diagnosis on Patients with Previously Undiagnosed Disease Splinter, K; Adams, DR; Bacino, CA et al. N. Engl. J. Med., DOI://10.1056/NEJMoa1714458 (2018)

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes Franceschini, N; Giambartolomei, C; de Vries, PS et al. Nat Commun, DOI://10.1038/s41467-018-07340-5 (2018)
Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells Mudd, JC; Busman-Sahay, K; DiNapoli, SR et al. Nat Commun, DOI://10.1038/s41467-018-05528-3 (2018)
The transcription factors TFE3 and TFEB amplify p53 dependent transcriptional programs in response to DNA damage Brady, OA; Jeong, E; Martina, JA; Pirooznia, M; Tunc, I; Puertollano, R; Elife, DOI://10.7554/eLife.40856 (2018)
Tenectin recruits integrin to stabilize bouton architecture and regulate vesicle release at the Drosophila neuromuscular junction Wang, Q; Han, TH; Nguyen, P; Jarnik, M; Serpe, M; Elife, DOI://10.7554/eLife.35518 (2018)
CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy Fry, TJ; Shah, NN; Orentas, RJ et al. Nat. Med., DOI://10.1038/nm.4441 (2018)
Mutant IL-7Rα and mutant NRas are sufficient to induce murine T cell acute lymphoblastic leukemia Cramer, SD; Hixon, JA; Andrews, C et al. Leukemia, DOI://10.1038/s41375-017-0001-0 (2018)
Bi-allelic CCDC47 Variants Cause a Disorder Characterized by Woolly Hair, Liver Dysfunction, Dysmorphic Features, and Global Developmental Delay Morimoto, M; Waller-Evans, H; Ammous, Z et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2018.09.014 (2018)
De Novo Missense Variants in TRAF7 Cause Developmental Delay, Congenital Anomalies, and Dysmorphic Features Tokita, MJ; Chen, CA; Chitayat, D et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2018.06.005 (2018)
Evaluation of Recipients of Positive and Negative Secondary Findings Evaluations in a Hybrid CLIA-Research Sequencing Pilot Sapp, JC; Johnston, JJ; Driscoll, K et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2018.07.018 (2018)
Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression Guo, W; Machado-Vieira, R; Mathew, S et al. Transl Psychiatry, DOI://10.1038/s41398-018-0311-7 (2018)
IFIT1 Exerts Opposing Regulatory Effects on the Inflammatory and Interferon Gene Programs in LPS-Activated Human Macrophages John, SP; Sun, J; Carlson, RJ et al. Cell Rep, DOI://10.1016/j.celrep.2018.09.002 (2018)
GWAS of epigenetic aging rates in blood reveals a critical role for TERT Lu, AT; Xue, L; Salfati, EL et al. Nat Commun, DOI://10.1038/s41467-017-02697-5 (2018)

Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study Teslovich, TM; Kim, DS; Yin, X et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddy067 (2018)
Altered DNA Methylation Patterns Associated With Clinically Relevant Increases in PTSD Symptoms and PTSD Symptom Profiles in Military Personnel Martin, C; Cho, YE; Kim, H et al. Biol Res Nurs, DOI://10.1177/1099800418758951 (2018)
Human retinoic acid-regulated CD161+ regulatory T cells support wound repair in intestinal mucosa Povoleri, GAM; Nova-Lamperti, E; Scottà, C et al. Nat. Immunol., DOI://10.1038/s41590-018-0230-z (2018)
Anthropoid primate-specific retroviral element THE1B controls expression of CRH in placenta and alters gestation length Dunn-Fletcher, CE; Muglia, LM; Pavlicev, M et al. PLoS Biol., DOI://10.1371/journal.pbio.2006337 (2018)
Interactions between genetic variation and cellular environment in skeletal muscle gene expression Taylor, DL; Knowles, DA; Scott, LJ et al. PLoS ONE, DOI://10.1371/journal.pone.0195788 (2018)
Analysis of Meiotic Double-Strand Break Initiation in Mammals Brick, K; Pratto, F; Sun, CY; Camerini-Otero, RD; Petukhova, G; Meth. Enzymol., DOI://10.1016/bs.mie.2017.11.037 (2018)

Genome-wide Identification of Structure-Forming Repeats as Principal Sites of Fork Collapse upon ATR Inhibition Shastri, N; Tsai, YC; Hile, S et al. Mol. Cell, DOI://10.1016/j.molcel.2018.08.047 (2018)
Automated Cervical Screening and Triage, Based on HPV Testing and Computer-Interpreted Cytology Yu, K; Hyun, N; Fetterman, B et al. J. Natl. Cancer Inst., DOI://10.1093/jnci/djy044 (2018)
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation Teumer, A; Chaker, L; Groeneweg, S et al. Nat Commun, DOI://10.1038/s41467-018-06356-1 (2018)
Molecular basis of Mitomycin C enhanced corneal sensory nerve repair after debridement wounding Stepp, MA; Pal-Ghosh, S; Tadvalkar, G; Li, L; Brooks, SR; Morasso, MI; Sci Rep, DOI://10.1038/s41598-018-35090-3 (2018)
MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype Plantamura, E; Dzutsev, A; Chamaillard, M et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1722372115 (2018)
Subcutaneous adipose tissue imaging of human obesity reveals two types of adipocyte membranes: Insulin-responsive and -nonresponsive McCormick, CD; Waters, HN; Bezrukov, L et al. J. Biol. Chem., DOI://10.1074/jbc.RA118.003751 (2018)

SPT6 interacts with NSD2 and facilitates interferon-induced transcription Ouda, R; Sarai, N; Nehru, V et al. FEBS Lett., DOI://10.1002/1873-3468.13069 (2018)
Isolation of Adult Spinal Cord Nuclei for Massively Parallel Single-nucleus RNA Sequencing Matson, KJE; Sathyamurthy, A; Johnson, KR; Kelly, MC; Kelley, MW; Levine, AJ; J Vis Exp, DOI://10.3791/58413 (2018)
Generation of Tumor Antigen-Specific iPSC-Derived Thymic Emigrants Using a 3D Thymic Culture System Vizcardo, R; Klemen, ND; Islam, SMR et al. Cell Rep, DOI://10.1016/j.celrep.2018.02.087 (2018)
Transcriptional profiling reveals gland-specific differential expression in the three major salivary glands of the adult mouse Gao, X; Oei, MS; Ovitt, CE; Sincan, M; Melvin, JE; Physiol. Genomics, DOI://10.1152/physiolgenomics.00124.2017 (2018)
Replacing C189 in the bZIP domain of Zta with S, T, V, or A changes DNA binding specificity to four types of double-stranded DNA Ray, S; Tillo, D; Assad, N et al. Biochem. Biophys. Res. Commun., DOI://10.1016/j.bbrc.2018.05.080 (2018)
Interferon stimulation creates chromatin marks and establishes transcriptional memory Kamada, R; Yang, W; Zhang, Y et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1720930115 (2018)
Lipid-dependence of target membrane stability during influenza viral fusion Haldar, S; Mekhedov, E; McCormick, CD; Blank, PS; Zimmerberg, J; J. Cell. Sci., DOI://10.1242/jcs.218321 (2018)
Human bone marrow assessment by single-cell RNA sequencing, mass cytometry, and flow cytometry Oetjen, KA; Lindblad, KE; Goswami, M et al. JCI Insight, DOI://10.1172/jci.insight.124928 (2018)
Structural disorder in four-repeat Tau fibrils reveals a new mechanism for barriers to cross-seeding of Tau isoforms Weismiller, HA; Murphy, R; Wei, G; Ma, B; Nussinov, R; Margittai, M; J. Biol. Chem., DOI://10.1074/jbc.RA118.005316 (2018)
Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy Yossef, R; Tran, E; Deniger, DC et al. JCI Insight, DOI://10.1172/jci.insight.122467 (2018)
Dynamic analysis of human tyrosinase intra-melanosomal domain and mutant variants to further understand oculocutaneous albinism type 1 Farney, SK; Dolinska, MB; Sergeev, YV; J Anal Pharm Res, DOI://10.15406/japlr.2018.07.00293 (2018)
Structural Constraints at the Trimer Apex Stabilize the HIV-1 Envelope in a Closed, Antibody-Protected Conformation Guzzo, C; Zhang, P; Liu, Q et al. MBio, DOI://10.1128/mBio.00955-18 (2018)
Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism Arbore, G; West, EE; Rahman, J et al. Nat Commun, DOI://10.1038/s41467-018-06706-z (2018)
Conserved mRNA-granule component Scd6 targets Dhh1 to repress translation initiation and activates Dcp2-mediated mRNA decay in vivo Zeidan, Q; He, F; Zhang, F; Zhang, H; Jacobson, A; Hinnebusch, AG; PLoS Genet., DOI://10.1371/journal.pgen.1007806 (2018)
Intraclass correlation: Improved modeling approaches and applications for neuroimaging Chen, G; Taylor, PA; Haller, SP et al. Hum Brain Mapp, DOI://10.1002/hbm.23909 (2018)
Exome sequencing of a large family identifies potential candidate genes contributing risk to bipolar disorder Zhang, T; Hou, L; Chen, DT; McMahon, FJ; Wang, JC; Rice, JP; Gene, DOI://10.1016/j.gene.2017.12.025 (2018)
Human defects in STAT3 promote oral mucosal fungal and bacterial dysbiosis Abusleme, L; Diaz, PI; Freeman, AF et al. JCI Insight, DOI://10.1172/jci.insight.122061 (2018)
Integrative analysis of the epigenetic basis of muscle-invasive urothelial carcinoma Sanford, T; Meng, MV; Railkar, R; Agarwal, PK; Porten, SP; Clin Epigenetics, DOI://10.1186/s13148-018-0451-x (2018)
Pain control through selective chemo-axotomy of centrally projecting TRPV1+ sensory neurons Sapio, MR; Neubert, JK; LaPaglia, DM et al. J. Clin. Invest., DOI://10.1172/JCI94331 (2018)
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity Turcot, V; Lu, Y; Highland, HM et al. Nat. Genet., DOI://10.1038/s41588-017-0011-x (2018)
Whole genome screen reveals a novel relationship between Wolbachia levels and Drosophila host translation Grobler, Y; Yun, CY; Kahler, DJ et al. PLoS Pathog., DOI://10.1371/journal.ppat.1007445 (2018)
Topoisomerase 3β interacts with RNAi machinery to promote heterochromatin formation and transcriptional silencing in Drosophila Lee, SK; Xue, Y; Shen, W et al. Nat Commun, DOI://10.1038/s41467-018-07101-4 (2018)
Frequency-dependent tACS modulation of BOLD signal during rhythmic visual stimulation Chai, Y; Sheng, J; Bandettini, PA; Gao, JH; Hum Brain Mapp, DOI://10.1002/hbm.23990 (2018)
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes Mahajan, A; Wessel, J; Willems, SM et al. Nat. Genet., DOI://10.1038/s41588-018-0084-1 (2018)
Neurological soft signs and cognitive performance in early childhood Alamiri, B; Nelson, C; Fitzmaurice, GM; Murphy, JM; Gilman, SE; Dev Psychol, DOI://10.1037/dev0000566 (2018)
Identifying HIPK1 as Target of miR-22-3p Enhancing Recombinant Protein Production From HEK 293 Cell by Using Microarray and HTP siRNA Screen Inwood, S; Buehler, E; Betenbaugh, M; Lal, M; Shiloach, J; Biotechnol J, DOI://10.1002/biot.201700342 (2018)
Learning recurrent dynamics in spiking networks Kim, CM; Chow, CC; Elife, DOI://10.7554/eLife.37124 (2018)
Decrypting the Heat Activation Mechanism of TRPV1 Channel by Molecular Dynamics Simulation Wen, H; Zheng, W; Biophys. J., DOI://10.1016/j.bpj.2017.10.034 (2018)
Two RNase H2 Mutants with Differential rNMP Processing Activity Reveal a Threshold of Ribonucleotide Tolerance for Embryonic Development Uehara, R; Cerritelli, SM; Hasin, N et al. Cell Rep, DOI://10.1016/j.celrep.2018.10.019 (2018)
Patterns of Physical Activity and Sedentary Behavior for Older Adults with Alzheimer's Disease, Mild Cognitive Impairment, and Cognitively Normal in Hong Kong Lu, Z; Harris, TB; Shiroma, EJ; Leung, J; Kwok, T; J. Alzheimers Dis., DOI://10.3233/JAD-180805 (2018)

Re-annotation of eight Drosophila genomes Yang, H; Jaime, M; Polihronakis, M et al. Life Sci Alliance, DOI://10.26508/lsa.201800156 (2018)
Breakthrough in GPCR Crystallography and Its Impact on Computer-Aided Drug Design Ciancetta, A; Jacobson, KA; Methods Mol. Biol., DOI://10.1007/978-1-4939-7465-8_3 (2018)
A small single-domain protein folds through the same pathway on and off the ribosome Guinn, EJ; Tian, P; Shin, M; Best, RB; Marqusee, S; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1810517115 (2018)
Development and differentiation of early innate lymphoid progenitors Harly, C; Cam, M; Kaye, J; Bhandoola, A; J. Exp. Med., DOI://10.1084/jem.20170832 (2018)
Metabolic remodelling of glucose, fatty acid and redox pathways in the heart of type 2 diabetic mice Cortassa, S; Caceres, V; Tocchetti, CG et al. J. Physiol. (Lond.), DOI://10.1113/JP276824 (2018)
The shape of the bacterial ribosome exit tunnel affects cotranslational protein folding Kudva, R; Tian, P; Pardo-Avila, F et al. Elife, DOI://10.7554/eLife.36326 (2018)

Dose coefficients of mesh-type ICRP reference computational phantoms for idealized external exposures of photons and electrons Yeom YS; Choi C; et al Nuclear Engineering and Technology, doi://10.1016/j.net.2018.12.006 (2018)
A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression Kycia, I; Wolford, BN; Huyghe, JR et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2018.02.020 (2018)
On the convergence of multi-scale free energy simulations König, G; Brooks, BR; Thiel, W; York, DM; Mol Simul, DOI://10.1080/08927022.2018.1475741 (2018)
Accelerated and Improved Differentiation of Retinal Organoids from Pluripotent Stem Cells in Rotating-Wall Vessel Bioreactors DiStefano, T; Chen, HY; Panebianco, C et al. Stem Cell Reports, DOI://10.1016/j.stemcr.2017.11.001 (2018)
Investigation of a Cluster of Sphingomonas koreensis Infections Johnson, RC; Deming, C; Conlan, S et al. N. Engl. J. Med., DOI://10.1056/NEJMoa1803238 (2018)
Intrinsic Dynamics of a Human Gene Reveal the Basis of Expression Heterogeneity Rodriguez, J; Ren, G; Day, CR; Zhao, K; Chow, CC; Larson, DR; Cell, DOI://10.1016/j.cell.2018.11.026 (2018)
Prevalence of pathogenic/likely pathogenic variants in the 24 cancer genes of the ACMG Secondary Findings v2.0 list in a large cancer cohort and ethnicity-matched controls Kim, J; Luo, W; Wang, M et al. Genome Med, DOI://10.1186/s13073-018-0607-5 (2018)
A dysbiotic microbiome triggers TH17 cells to mediate oral mucosal immunopathology in mice and humans Nicolas Dutzan, Tetsuhiro Kajikawa, Loreto Abusleme et al. Mucosal Immunity, 10.1126/scitranslmed.aat0797 (2018)
Amyloid Fibril Design: Limiting Structural Polymorphism in Alzheimer's Aβ Protofilaments Bartomiej Tywoniuk, Ye Yuan, Sarah McCartan, Beata Maria Szyd&#;owska, Florentina Tofoleanu, Bernard R. Brooks, and Nicolae-Viorel Buchete J. Phys. Chem B, 10.1021/acs.jpcb.8b07423 (2018)
Probing the hras-1Y i-motif with small molecules Sara N. Journey, Stephanie L. Alden, Will M. Hewitt, Megan L. Peach, Marc C. Nicklaus and John S. Schneekloth Jr Med. Chem. Commun.,, 10.1039/C8MD00311D (2018)
Structure activity relationship of 2-arylalkynyl-adenine derivatives as human A3 adenosine receptor antagonist Yu, J; Mannes, P; Jung, YH et al. Medchemcomm, DOI://10.1039/c8md00317c (2018)
Renal compartment-specific genetic variation analyses identify new pathways in chronic kidney disease Qiu, C; Huang, S; Park, J et al. Nat. Med., DOI://10.1038/s41591-018-0194-4 (2018)

Finding the baby in the bath water - evidence for task-specific changes in resting state functional connectivity evoked by training Steel, A; Thomas, C; Trefler, A; Chen, G; Baker, CI; Neuroimage, DOI://10.1016/j.neuroimage.2018.12.038 (2018)
Dynamic transcriptome profiling dataset of vaccinia virus obtained from long-read sequencing techniques Tombácz, D; Prazsák, I; Szucs, A; Dénes, B; Snyder, M; Boldogkoi, Z; Gigascience, DOI://10.1093/gigascience/giy139 (2018)
From Molecules to Mechanisms: Functional Proteomics and Its Application to Renal Tubule Physiology Rinschen, MM; Limbutara, K; Knepper, MA; Payne, DM; Pisitkun, T; Physiol. Rev., DOI://10.1152/physrev.00057.2017 (2018)
RNA-Protein Interactions Prevent Long RNA Duplex Formation: Implications for the Design of RNA-Based Therapeutics Bindewald, E; Dai, L; Kasprzak, WK; Kim, T; Gu, S; Shapiro, BA; Molecules, DOI://10.3390/molecules23123329 (2018)
CRISPR/Cas9-mediated gene knockin in the hydroid Hydractinia symbiolongicarpus Sanders, SM; Ma, Z; Hughes, JM et al. BMC Genomics, DOI://10.1186/s12864-018-5032-z (2018)
In Silico Mutagenesis: Decreasing the Immunogenicity of Botulinum Toxin Type A Evander Emeltan Tjoa, S; Maria Vianney, Y; Emantoko Dwi Putra, S; J. Biomol. Struct. Dyn., DOI://10.1080/07391102.2018.1559100 (2018)

BoostMe accurately predicts DNA methylation values in whole-genome bisulfite sequencing of multiple human tissues Zou, LS; Erdos, MR; Taylor, DL et al. BMC Genomics, DOI://10.1186/s12864-018-4766-y (2018)
Barcoding of Macaque Hematopoietic Stem and Progenitor Cells: A Robust Platform to Assess Vector Genotoxicity Yabe, IM; Truitt, LL; Espinoza, DA et al. Mol Ther Methods Clin Dev, DOI://10.1016/j.omtm.2018.10.009 (2018)
The Inner Ear Heat Shock Transcriptional Signature Identifies Compounds That Protect Against Aminoglycoside Ototoxicity Ryals, M; Morell, RJ; Martin, D et al. Front Cell Neurosci, DOI://10.3389/fncel.2018.00445 (2018)
A Divergent Strain of Culex pipiens-Associated Tunisia Virus in the Malaria Vector Anopheles epiroticus Debat, HJ; Ribeiro, JMC; Microbiol Resour Announc, DOI://10.1128/MRA.01026-18 (2018)
The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin Jang, SM; Zhang, Y; Utani, K et al. Nat Commun, DOI://10.1038/s41467-018-05177-6 (2018)
Metagenomic Discovery of 83 New Human Papillomavirus Types in Patients with Immunodeficiency Pastrana, DV; Peretti, A; Welch, NL et al. mSphere, DOI://10.1128/mSphereDirect.00645-18 (2018)
Functional and association analysis of an Amerindian-derived population-specific p.(Thr280Met) variant in RBPJL, a component of the PTF1 complex Nair, AK; Sutherland, JR; Traurig, M et al. Eur. J. Hum. Genet., DOI://10.1038/s41431-017-0062-6 (2018)
Persistent upregulation of the β-tubulin tubb6, linked to muscle regeneration, is a source of microtubule disorganization in dystrophic muscle Randazzo, D; Khalique, U; Belanto, JJ et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddy418 (2018)
Peptidylarginine deiminases 2 and 4 modulate innate and adaptive immune responses in TLR-7-dependent lupus Liu, Y; Lightfoot, YL; Seto, N et al. JCI Insight, DOI://10.1172/jci.insight.124729 (2018)
A temporal deconvolution algorithm for multiecho functional MRI Cesar Caballero Gaudes ; Peter A. Bandettini ; Javier Gonzalez-Castillo 2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018), 10.1109/ISBI.2018.8363649 (2018)
Folding pathway of an Ig domain is conserved on and off the ribosome Tian, P; Steward, A; Kudva, R et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1810523115 (2018)
Reply to Edemir: Physiological regulation and single-cell RNA sequencing Chen, L; Lee, JW; Chou, CL et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1720333115 (2018)

AbDesigner3D: a structure-guided tool for peptide-based antibody production Saethang, T; Hodge, K; Kimkong, I; Payne, DM; Knepper, MA; Pisitkun, T; Bioinformatics, DOI://10.1093/bioinformatics/bty055 (2018)
Whole-genome sequencing of 175 Mongolians uncovers population-specific genetic architecture and gene flow throughout North and East Asia Bai, H; Guo, X; Narisu, N et al. Nat. Genet., DOI://10.1038/s41588-018-0250-5 (2018)
Helios is a key transcriptional regulator of outer hair cell maturation Chessum, L; Matern, MS; Kelly, MC et al. Nature, DOI://10.1038/s41586-018-0728-4 (2018)
Comparing the performance of selected variant callers using synthetic data and genome segmentation Bian, X; Zhu, B; Wang, M et al. BMC Bioinformatics, DOI://10.1186/s12859-018-2440-7 (2018)
Direct observation of topoisomerase IA gate dynamics Mills, M; Tse-Dinh, YC; Neuman, KC; Nat. Struct. Mol. Biol., DOI://10.1038/s41594-018-0158-x (2018)
Proximity-CLIP provides a snapshot of protein-occupied RNA elements in subcellular compartments Benhalevy, D; Anastasakis, DG; Hafner, M; Nat. Methods, DOI://10.1038/s41592-018-0220-y (2018)
An integrative systems biology approach for precision medicine in diabetic kidney disease Mulder, S; Hamidi, H; Kretzler, M; Ju, W; Diabetes Obes Metab, DOI://10.1111/dom.13416 (2018)
Identification and functional analysis of a novel G310D variant in the insulin-like growth factor 1 receptor (IGF1R) gene associated with type 2 diabetes in American Indians Muller, YL; Skelton, G; Piaggi, P et al. Diabetes Metab. Res. Rev., DOI://10.1002/dmrr.2994 (2018)
How to fold and protect mitochondrial ribosomal RNA with fewer guanines Hosseini, M; Roy, P; Sissler, M; Zirbel, CL; Westhof, E; Leontis, N; Nucleic Acids Res., DOI://10.1093/nar/gky762 (2018)
TRPV1 pore turret dictates distinct DkTx and capsaicin gating Geron, M; Kumar, R; Zhou, W; Faraldo-Gómez, JD; Vásquez, V; Priel, A; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1809662115 (2018)
Acetylation of Cytidine in mRNA Promotes Translation Efficiency Arango, D; Sturgill, D; Alhusaini, N et al. Cell, DOI://10.1016/j.cell.2018.10.030 (2018)
Mutational and Phenotypic Spectra of KCNE1 deficiency in Jervell and Lange-Nielsen Syndrome and Romano-Ward Syndrome Faridi, R; Tona, R; Brofferio, A et al. Hum. Mutat., DOI://10.1002/humu.23689 (2018)

Self-adaptive multiscaling algorithm for efficient simulations of many-protein systems in crowded conditions Hassan, SA Phys Chem Chem Phys, DOI://10.1039/c8cp05517c (2018)
Influence of Fetal and Maternal Genetic Susceptibility to Obesity on Birthweight in African Ancestry Populations Shrestha, D; Rahman, ML; Workalemahu, T; Zhu, C; Tekola-Ayele, F; Front Genet, DOI://10.3389/fgene.2018.00511 (2018)
hsegHMM: hidden Markov model-based allele-specific copy number alteration analysis accounting for hypersegmentation Choo-Wosoba, H; Albert, PS; Zhu, B; BMC Bioinformatics, DOI://10.1186/s12859-018-2412-y (2018)
Single-cell RNA sequencing of the mammalian pineal gland identifies two pinealocyte subtypes and cell type-specific daily patterns of gene expression Mays, JC; Kelly, MC; Coon, SL et al. PLoS ONE, DOI://10.1371/journal.pone.0205883 (2018)
HJURP antagonizes CENP-A mislocalization driven by the H3.3 chaperones HIRA and DAXX Nye, J; Sturgill, D; Athwal, R; Dalal, Y; PLoS ONE, DOI://10.1371/journal.pone.0205948 (2018)
Characterization of spatial and temporal development of Type I and Type II hair cells in the mouse utricle using new cell-type-specific markers McInturff, S; Burns, JC; Kelley, MW; Biol Open, DOI://10.1242/bio.038083 (2018)
Current progress and future opportunities in applications of bioinformatics for biodefense and pathogen detection: report from the Winter Mid-Atlantic Microbiome Meet-up, College Park, MD, January 10, 2018 Meisel, JS; Nasko, DJ; Brubach, B et al. Microbiome, DOI://10.1186/s40168-018-0582-5 (2018)
Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination Steklov, M; Pandolfi, S; Baietti, MF et al. Science, DOI://10.1126/science.aap7607 (2018)
The effect of repeated stimulated granulocyte donations on hematopoietic indexes in donors: a 24-year donor center experience Szymanski, J; Troendle, J; Leitman, S; Hong, H; Yau, YY; Cantilena, C; Transfusion, DOI://10.1111/trf.15000 (2018)
Mechanism of FACT removal from transcribed genes by anticancer drugs curaxins Chang, HW; Valieva, ME; Safina, A et al. Sci Adv, DOI://10.1126/sciadv.aav2131 (2018)
Quantifying differences between passive and task-evoked intrinsic functional connectivity in a large-scale brain simulation Ulloa, A; Horwitz, B; Brain Connect, DOI://10.1089/brain.2018.0620 (2018)
Genome Sequences of 15 Klebsiella sp. Isolates from Sugarcane Fields in Colombia's Cauca Valley Medina-Cordoba, LK; Chande, AT; Rishishwar, L et al. Genome Announc, DOI://10.1128/genomeA.00104-18 (2018)

Amycomicin is a potent and specific antibiotic discovered with a targeted interaction screen Pishchany, G; Mevers, E; Ndousse-Fetter, S et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1807613115 (2018)
ONC201 kills breast cancer cells in vitro by targeting mitochondria Greer, YE; Porat-Shliom, N; Nagashima, K et al. Oncotarget, DOI://10.18632/oncotarget.24862 (2018)
RNA sequencing of kidney distal tubule cells reveals multiple mediators of chronic aldosterone action Poulsen, SB; Limbutara, K; Fenton, RA; Pisitkun, T; Christensen, BM; Physiol. Genomics, DOI://10.1152/physiolgenomics.00084.2017 (2018)
Transcriptome signature for dietary fructose-specific changes in rat renal cortex: A quantitative approach to physiological relevance Gonzalez-Vicente, A; Garvin, JL; Hopfer, U; PLoS ONE, DOI://10.1371/journal.pone.0201293 (2018)
Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists Tosh, DK; Ciancetta, A; Mannes, P et al. ACS Omega, DOI://10.1021/acsomega.8b01237 (2018)
High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping Czerniecki, SM; Cruz, NM; Harder, JL et al. Cell Stem Cell, DOI://10.1016/j.stem.2018.04.022 (2018)
Effect of over expressing protective antigen on global gene transcription in Bacillus anthracis BH500 Sharma, AK; Leppla, SH; Pomerantsev, AP; Shiloach, J; Sci Rep, DOI://10.1038/s41598-018-34196-y (2018)
Genetic Ancestry of Hadza and Sandawe Peoples Reveals Ancient Population Structure in Africa Shriner, D; Tekola-Ayele, F; Adeyemo, A; Rotimi, CN; Genome Biol Evol, DOI://10.1093/gbe/evy051 (2018)
Correction: A Novel, Noncanonical BMP Pathway Modulates Synapse Maturation at the Drosophila Neuromuscular Junction Sulkowski, MJ; Han, TH; Ott, C et al. PLoS Genet., DOI://10.1371/journal.pgen.1007343 (2018)
--Mitochondrial ATP synthase dimers spontaneously associate due to a long-range membrane-induced force Anselmi, C; Davies, KM; Faraldo-Gómez, JD; J. Gen. Physiol., DOI://10.1085/jgp.201812033 (2018)
Phenotypic expansion in DDX3X - a common cause of intellectual disability in females Wang, X; Posey, JE; Rosenfeld, JA et al. Ann Clin Transl Neurol, DOI://10.1002/acn3.622 (2018)
A Comparison of QM/MM Simulations with and without the Drude Oscillator Model Based on Hydration Free Energies of Simple Solutes König, G; Pickard, FC; Huang, J et al. Molecules, DOI://10.3390/molecules23102695 (2018)
BRG1 governs glucocorticoid receptor interactions with chromatin and pioneer factors across the genome Hoffman, JA; Trotter, KW; Ward, JM; Archer, TK; Elife, DOI://10.7554/eLife.35073 (2018)
Mitochondrial chaotic dynamics: Redox-energetic behavior at the edge of stability Kembro, JM; Cortassa, S; Lloyd, D; Sollott, SJ; Aon, MA; Sci Rep, DOI://10.1038/s41598-018-33582-w (2018)
Towards Personalized Medicine: An Improved De Novo Assembly Procedure for Early Detection of Drug Resistant HIV Minor Quasispecies in Patient Samples Huang, C; Sam, V; Du, S et al. Bioinformation, DOI://10.6026/97320630014449 (2018)
JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies Sanchez, GAM; Reinhardt, A; Ramsey, S et al. J. Clin. Invest., DOI://10.1172/JCI98814 (2018)
Collecting duct principal, but not intercalated, cell prorenin receptor regulates renal sodium and water excretion Ramkumar, N; Stuart, D; Mironova, E et al. Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00122.2018 (2018)
Detection and Distinction of Mild Brain Injury Effects in a Ferret Model Using Diffusion Tensor MRI (DTI) and DTI-Driven Tensor-Based Morphometry (D-TBM) Hutchinson, EB; Schwerin, SC; Radomski, KL et al. Front Neurosci, DOI://10.3389/fnins.2018.00573 (2018)
Approaches to the discovery of non-invasive urinary biomarkers of prostate cancer Jedinak, A; Loughlin, KR; Moses, MA; Oncotarget, DOI://10.18632/oncotarget.25946 (2018)
Sequence-based searching of custom proteome and transcriptome databases Medvar, B; Sarkar, A; Knepper, M; Pisitkun, T; Physiol Rep, DOI://10.14814/phy2.13846 (2018)
STAT5B: A Differential Regulator of the Life and Death of CD4+ Effector Memory T Cells Majri, SS; Fritz, JM; Villarino, AV et al. J. Immunol., DOI://10.4049/jimmunol.1701133 (2018)
Tilted, Uninterrupted, Monomeric HIV-1 gp41 Transmembrane Helix from Residual Dipolar Couplings Chiliveri, SC; Louis, JM; Ghirlando, R; Baber, JL; Bax, A; J. Am. Chem. Soc., DOI://10.1021/jacs.7b10245 (2018)
A function-blocking CD47 antibody modulates extracellular vesicle-mediated intercellular signaling between breast carcinoma cells and endothelial cells Kaur, S; Elkahloun, AG; Singh, SP; Arakelyan, A; Roberts, DD; J Cell Commun Signal, DOI://10.1007/s12079-017-0428-0 (2018)
Identification and functional analysis of SOX10 phosphorylation sites in melanoma Cronin, JC; Loftus, SK; Baxter, LL; Swatkoski, S; Gucek, M; Pavan, WJ; PLoS ONE, DOI://10.1371/journal.pone.0190834 (2018)

Whole-exome sequencing of nevoid basal cell carcinoma syndrome families and review of Human Gene Mutation Database PTCH1 mutation data Gianferante, DM; Rotunno, M; Dean, M et al. Mol Genet Genomic Med, DOI://10.1002/mgg3.498 (2018)
Renal release of Ac-SDKP is part of an antifibrotic peptidergic system in the kidney Romero, CA; Kumar, N; Nakagawa, P et al. Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00270.2018 (2018)
Expanded skin virome in DOCK8-deficient patients Tirosh, O; Conlan, S; Deming, C et al. Nat. Med., DOI://10.1038/s41591-018-0211-7 (2018)
Nuclear Transcriptomes of the Seven Neuronal Cell Types That Constitute the Drosophila Mushroom Bodies Shih, MM; Davis, FP; Henry, GL; Dubnau, J; G3 (Bethesda), DOI://10.1534/g3.118.200726 (2018)
A fast adaptive algorithm for computing whole-genome homology maps Chirag Jain, Sergey Koren, Alexander Dilthey, Adam M Phillippy, and Srinivas Aluru Bioinformatics, doi://10.1093/bioinformatics/bty597 (2018)
Clonal expansion and compartmentalized maintenance of rhesus macaque NK cell subsets Wu, C; Espinoza, DA; Koelle, SJ et al. Sci Immunol, DOI://10.1126/sciimmunol.aat9781 (2018)

Expanding the phenotype of COPA syndrome: a kindred with typical and atypical features Taveira-DaSilva, AM; Markello, TC; Kleiner, DE et al. J. Med. Genet., DOI://10.1136/jmedgenet-2018-105560 (2018)
RefSeq database growth influences the accuracy of k-mer-based lowest common ancestor species identification Nasko, DJ; Koren, S; Phillippy, AM; Treangen, TJ; Genome Biol., DOI://10.1186/s13059-018-1554-6 (2018)
Non-canonical Drosophila X chromosome dosage compensation and repressive topologically associated domains Lee, H; Oliver, B; Epigenetics Chromatin, DOI://10.1186/s13072-018-0232-y (2018)
Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke Cole, JW; Xu, H; Ryan, K et al. PLoS ONE, DOI://10.1371/journal.pone.0206554 (2018)
Genomic and Transcriptomic Characterization Links Cell Lines with Aggressive Head and Neck Cancers Cheng, H; Yang, X; Si, H et al. Cell Rep, DOI://10.1016/j.celrep.2018.10.007 (2018)
Modulation of Cl- signaling and ion transport by recruitment of kinases and phosphatases mediated by the regulatory protein IRBIT Vachel, L; Shcheynikov, N; Yamazaki, O et al. Sci Signal, DOI://10.1126/scisignal.aat5018 (2018)

Body-weight dependent dose coefficients for adults exposed to idealised external photon fields Lienard A Chang David Borrego and Choonsik Lee J. Radiological Protection, vol 38, no 4 (2018)
Molecular Determinants of Aβ42 Adsorption to Amyloid Fibril Surfaces Bellaiche, MMJ; Best, RB; J Phys Chem Lett, DOI://10.1021/acs.jpclett.8b02375 (2018)
Argonaute2 attenuates active transcription by limiting RNA Polymerase II elongation in Drosophila melanogaster Nazer, E; Dale, RK; Palmer, C; Lei, EP; Sci Rep, DOI://10.1038/s41598-018-34115-1 (2018)
Enhanced expression and distinctive characterization of a long-acting FGF21 and its potential to alleviate nonalcoholic steatohepatitis Yin, J; Bao, L; Chen, R; Gao, W; Gao, X; Yao, W; Biochimie, DOI://10.1016/j.biochi.2018.05.020 (2018)
Brain regions modulated during covert visual attention in the macaque Bogadhi, AR; Bollimunta, A; Leopold, DA; Krauzlis, RJ; Sci Rep, DOI://10.1038/s41598-018-33567-9 (2018)
Variable population prevalence estimates of germline TP53 variants: A gnomAD-based analysis de Andrade, KC; Frone, MN; Wegman-Ostrosky, T et al. Hum. Mutat., DOI://10.1002/humu.23673 (2018)

De novo assembly of haplotype-resolved genomes with trio binning Koren, S; Rhie, A; Walenz, BP et al. Nat. Biotechnol., DOI://10.1038/nbt.4277 (2018)
Structural interpretation of DNA-protein hydroxyl-radical footprinting experiments with high resolution using HYDROID Shaytan, AK; Xiao, H; Armeev, GA et al. Nat Protoc, DOI://10.1038/s41596-018-0048-z (2018)
Cell-type-specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes Zhang, T; Choi, J; Kovacs, MA et al. Genome Res., DOI://10.1101/gr.233304.117 (2018)
Peptide-MHC (pMHC) binding to a human antiviral T cell receptor induces long-range allosteric communication between pMHC- and CD3-binding sites Rangarajan, S; He, Y; Chen, Y et al. J. Biol. Chem., DOI://10.1074/jbc.RA118.003832 (2018)
Comparison of the umbrella sampling and the double decoupling method in binding free energy predictions for SAMPL6 octa-acid host-guest challenges Nishikawa, N; Han, K; Wu, X; Tofoleanu, F; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-018-0166-2 (2018)
Molecular Recognition between Aβ-Specific Single-Domain Antibody and Aβ Misfolded Aggregates Mingzhen Zhang, Jie Zheng, Ruth Nussinov and Buyong Ma Antibodies, doi:10.3390/antib7030025 (2018)

Single-Molecule Analysis Reveals Linked Cycles of RSC Chromatin Remodeling and Ace1p Transcription Factor Binding in Yeast Mehta, GD; Ball, DA; Eriksson, PR et al. Mol. Cell, DOI://10.1016/j.molcel.2018.09.009 (2018)
Global genetic insight contributed by consanguineous Pakistani families segregating hearing loss Richard, EM; Santos-Cortez, RL; Faridi, R et al. Hum. Mutat., DOI://10.1002/humu.23666 (2018)
Accelerating QM/MM Free Energy Computations via Intramolecular Force Matching Hudson, PS; Boresch, S; Rogers, DM; Woodcock, HL; J Chem Theory Comput, DOI://10.1021/acs.jctc.8b00517 (2018)
Loss of functional connectivity is an early imaging marker in primary lateral sclerosis Clark, MG; Smallwood Shoukry, R; Huang, CJ; Danielian, LE; Bageac, D; Floeter, MK; Amyotroph Lateral Scler Frontotemporal Degener, DOI://10.1080/21678421.2018.1517180 (2018)
Estimating onset time from longitudinal data in the presence of measurement error with application to estimating gestational age from maternal anthropometry during pregnancy Ortega-Villa, AM; Albert, PS; Stat Med, DOI://10.1002/sim.7955 (2018)
CRISPro: An Automated Pipeline for Protein Conformation Stabilization by Proline Rawi, R; Shen, CH; Kwong, PD; Chuang, GY; J Chem Inf Model, DOI://10.1021/acs.jcim.8b00592 (2018)
Impact of induced anxiety on neural responses to monetary incentives Gorka, AX; Fuchs, B; Grillon, C; Ernst, M; Soc Cogn Affect Neurosci, DOI://10.1093/scan/nsy082 (2018)
Antigen binding allosterically promotes Fc receptor recognition Zhao, J; Nussinov, R; Ma, B; MAbs, DOI://10.1080/19420862.2018.1522178 (2018)
Progressing super-enhancer landscape during mammary differentiation controls tissue-specific gene regulation Lee, HK; Willi, M; Shin, HY; Liu, C; Hennighausen, L; Nucleic Acids Res., DOI://10.1093/nar/gky891 (2018)
Origin of Internal Friction in Disordered Proteins Depends on Solvent Quality Zheng, W; Hofmann, H; Schuler, B; Best, RB; J Phys Chem B, DOI://10.1021/acs.jpcb.8b07425 (2018)
Mutation frequency is not increased in CRISPR-Cas9-edited mice Willi, M; Smith, HE; Wang, C; Liu, C; Hennighausen, L; Nat. Methods, DOI://10.1038/s41592-018-0148-2 (2018)
Force matching as a stepping stone to QM/MM CB[8] host/guest binding free energies: a SAMPL6 cautionary tale Hudson, PS; Han, K; Woodcock, HL; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-018-0165-3 (2018)

An explicit-solvent hybrid QM and MM approach for predicting pKa of small molecules in SAMPL6 challenge Prasad, S; Huang, J; Zeng, Q; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-018-0167-1 (2018)
Nutrient-Driven O-GlcNAcylation at Promoters Impacts Genome-Wide RNA Pol II Distribution Krause, MW; Love, DC; Ghosh, SK et al. Front Endocrinol (Lausanne), DOI://10.3389/fendo.2018.00521 (2018)
Evidence for the critical role of transmembrane helices 1 and 7 in substrate transport by human P-glycoprotein (ABCB1) Sajid, A; Lusvarghi, S; Chufan, EE; Ambudkar, SV; PLoS ONE, DOI://10.1371/journal.pone.0204693 (2018)
Principles of nucleosome organization revealed by single-cell micrococcal nuclease sequencing Lai, B; Gao, W; Cui, K et al. Nature, DOI://10.1038/s41586-018-0567-3 (2018)
Genetic history of Chad Shriner, D; Rotimi, CN; Am. J. Phys. Anthropol., DOI://10.1002/ajpa.23711 (2018)
Visualization and Interpretation of Convolutional Neural Network Predictions in Detecting Pneumonia in Pediatric Chest Radiographs S. Rajaraman, S. Candemir, I. Kim, G. Thoma, S. Antani Appl. Sci. , doi://10.3390/app8101715 (2018)

Identifying core biological processes distinguishing human eye tissues with precise systems-level gene expression analyses and weighted correlation networks Bryan, JM; Fufa, TD; Bharti, K; Brooks, BP; Hufnagel, RB; McGaughey, DM; Hum. Mol. Genet., DOI://10.1093/hmg/ddy239 (2018)
Structural elements required for coupling ion and substrate transport in the neurotransmitter transporter homolog LeuT Zhang, YW; Tavoulari, S; Sinning, S; Aleksandrova, AA; Forrest, LR; Rudnick, G; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1716870115 (2018)
Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia Kim, MY; Yu, KR; Kenderian, SS et al. Cell, DOI://10.1016/j.cell.2018.05.013 (2018)
Extensive sex differences at the initiation of genetic recombination Brick, K; Thibault-Sennett, S; Smagulova, F et al. Nature, DOI://10.1038/s41586-018-0492-5 (2018)
Transcriptional outcomes and kinetic patterning of gene expression in response to NF-κB activation Zhao, M; Joy, J; Zhou, W et al. PLoS Biol., DOI://10.1371/journal.pbio.2006347 (2018)
Proteomic approaches in kidney disease biomarker discovery Wu, Q; Fenton, RA; Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00421.2018 (2018)

Whole genome sequencing data for two individuals of Pakistani descent Khan, SY; Kabir, F; M'Hamdi, O et al. Sci Data, DOI://10.1038/sdata.2018.174 (2018)
Peptide and Protein Structure Prediction with a Simplified Continuum Solvent Model Steinbach, PJ J Phys Chem B, DOI://10.1021/acs.jpcb.8b07264 (2018)
Relation between single-molecule properties and phase behavior of intrinsically disordered proteins Dignon, GL; Zheng, W; Best, RB; Kim, YC; Mittal, J; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1804177115 (2018)
Robust Hund rule without Coulomb repulsion and exclusion principle in quantum antiferromagnetic chains of composite half spins Duki, SF; Yu, YK; J Phys Condens Matter, DOI://10.1088/1361-648X/aae169 (2018)
Random forest based classification of alcohol dependence patients and healthy controls using resting state MRI Zhu, X; Du, X; Kerich, M; Lohoff, FW; Momenan, R; Neurosci. Lett., DOI://10.1016/j.neulet.2018.04.007 (2018)
A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A Ciftci-Yilmaz, S; Au, WC; Mishra, PK et al. Genetics, DOI://10.1534/genetics.118.301305 (2018)

DNA methylation age is accelerated in alcohol dependence Rosen, AD; Robertson, KD; Hlady, RA et al. Transl Psychiatry, DOI://10.1038/s41398-018-0233-4 (2018)
Dynamics of Genome Alterations in Crohn's Disease-Associated Colorectal Carcinogenesis Hirsch, D; Wangsa, D; Zhu, YJ et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-0630 (2018)
EWS-FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine-glycine biosynthesis Sen, N; Cross, AM; Lorenzi, PL et al. Mol. Carcinog., DOI://10.1002/mc.22849 (2018)
Aneuploidy, TP53 mutation, and amplification of MYC correlate with increased intratumor heterogeneity and poor prognosis of breast cancer patients Oltmann, J; Heselmeyer-Haddad, K; Hernandez, LS et al. Genes Chromosomes Cancer, DOI://10.1002/gcc.22515 (2018)
Multiple claudin-claudin cis interfaces are required for tight junction strand formation and inherent flexibility Zhao, J; Krystofiak, ES; Ballesteros A et al. Comm. Biol. , doi://10.1038/s42003-018-0051-5 (2018)
Calmodulin (CaM) Activates PI3Kα by Targeting the "Soft" CaM-Binding Motifs in Both the nSH2 and cSH2 Domains of p85α Zhang M, Li Z, Wang G et al. J. Phys. Chem B, doi://10.1021/acs.jpcb.8b05982 (2018)

Functional and physical interaction between yeast Hsp90 and Hsp70 Kravats, AN; Hoskins, JR; Reidy, M et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1719969115 (2018)
The High Genetic Barrier of EFdA/MK-8591 Stems from Strong Interactions with the Active Site of Drug-Resistant HIV-1 Reverse Transcriptase Takamatsu, Y; Das, D; Kohgo, S et al. Cell Chem Biol, DOI://10.1016/j.chembiol.2018.07.014 (2018)
Mapping discontinuous epitopes for MRK-16, UIC2 and 4E3 antibodies to extracellular loops 1 and 4 of human P-glycoprotein Vahedi, S; Lusvarghi, S; Pluchino, K et al. Sci Rep, DOI://10.1038/s41598-018-30984-8 (2018)
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure Sung, YJ; Winkler, TW; de Las Fuentes, L et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2018.01.015 (2018)
Heterogeneity of calcium clock functions in dormant, dysrhythmically and rhythmically firing single pacemaker cells isolated from SA node Kim, MS; Maltsev, AV; Monfredi, O et al. Cell Calcium, DOI://10.1016/j.ceca.2018.07.002 (2018)
Trac-looping measures genome structure and chromatin accessibility Lai, B; Tang, Q; Jin, W et al. Nat. Methods, DOI://10.1038/s41592-018-0107-y (2018)

Experience-dependent structural plasticity targets dynamic filopodia in regulating dendrite maturation and synaptogenesis Sheng, C; Javed, U; Gibbs, M et al. Nat Commun, DOI://10.1038/s41467-018-05871-5 (2018)
Proteomic determination of the lysine acetylome and phosphoproteome in the rat native inner medullary collecting duct Hyndman, KA; Yang, CR; Jung, HJ; Umejiego, EN; Chou, CL; Knepper, MA; Physiol. Genomics, DOI://10.1152/physiolgenomics.00029.2018 (2018)
Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours Ma, X; Liu, Y; Liu, Y et al. Nature, DOI://10.1038/nature25795 (2018)
Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa Li, L; Jiao, X; D'Atri, I et al. PLoS Genet., DOI://10.1371/journal.pgen.1007504 (2018)
Argonaute-miRNA Complexes Silence Target mRNAs in the Nucleus of Mammalian Stem Cells Sarshad, AA; Juan, AH; Muler, AIC et al. Mol. Cell, DOI://10.1016/j.molcel.2018.07.020 (2018)
Identification of Retinal Ganglion Cell Firing Patterns Using Clustering Analysis Supplied with Failure Diagnosis Ghahari, A; Kumar, SR; Badea, TC; Int J Neural Syst, DOI://10.1142/S0129065718500089 (2018)

A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity Béziat, V; Li, J; Lin, JX et al. Sci Immunol, DOI://10.1126/sciimmunol.aat4956 (2018)
TM6SF2 Promotes Lipidation and Secretion of Hepatitis C Virus in Infected Hepatocytes Boyer, A; Park, SB; de Boer, Y; Li, Q; Liang, TJ; Gastroenterology, DOI://10.1053/j.gastro.2018.08.027 (2018)
Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease Yao, C; Chen, G; Song, C et al. Nat Commun, DOI://10.1038/s41467-018-05512-x (2018)
Distributed cortical structural properties contribute to motor cortical excitability and inhibition Dayan, E; López-Alonso, V; Liew, SL; Cohen, LG; Brain Struct Funct, DOI://10.1007/s00429-018-1722-1 (2018)
Dysregulated neutrophil responses and neutrophil extracellular trap formation and degradation in PAPA syndrome Mistry, P; Carmona-Rivera, C; Ombrello, AK et al. Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2018-213746 (2018)
Absolute and relative pKa predictions via a DFT approach applied to the SAMPL6 blind challenge Zeng, Q; Jones, MR; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-018-0150-x (2018)

Conformational ensemble of disordered proteins probed by solvent Paramagnetic Relaxation Enhancement (sPRE) Kooshapur, H; Schwieters, C; Tjandra, N; Angew. Chem. Int. Ed. Engl., DOI://10.1002/anie.201807365 (2018)
On testing for spatial correspondence between maps of human brain structure and function Alexander-Bloch, AF; Shou, H; Liu, S et al. Neuroimage, DOI://10.1016/j.neuroimage.2018.05.070 (2018)
Predictors of mosaic chromosome Y loss and associations with mortality in the UK Biobank Loftfield, E; Zhou, W; Graubard, BI et al. Sci Rep, DOI://10.1038/s41598-018-30759-1 (2018)
Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs Matthies, D; Bae, C; Toombes, GE et al. Elife, DOI://10.7554/eLife.37558 (2018)
A DNA methylation biomarker of alcohol consumption Liu, C; Marioni, RE; Hedman, ÅK et al. Mol. Psychiatry, DOI://10.1038/mp.2016.192 (2018)
Targeting the HTLV-I-Regulated BATF3/IRF4 Transcriptional Network in Adult T Cell Leukemia/Lymphoma Nakagawa, M; Shaffer, AL; Ceribelli, M et al. Cancer Cell, DOI://10.1016/j.ccell.2018.06.014 (2018)

Feasibility and accuracy of UF/NCI phantoms and Monte Carlo retrospective dosimetry in children treated on National Wilms Tumor Study protocols Kalapurakal, JA; Gopalakrishnan, M; Mille, M et al. Pediatr Blood Cancer, DOI://10.1002/pbc.27395 (2018)
Structure and energetic basis of overrepresented λ light chain in systemic light chain amyloidosis patients Zhao, J; Zhang, B; Zhu, J; Nussinov, R; Ma, B; Biochim. Biophys. Acta, DOI://10.1016/j.bbadis.2017.12.009 (2018)
Allosteric KRas4B Can Modulate SOS1 Fast and Slow Ras Activation Cycles Liao, TJ; Jang, H; Fushman, D; Nussinov, R; Biophys. J., DOI://10.1016/j.bpj.2018.07.016 (2018)
A coevolution-guided model for the rotor of the bacterial flagellar motor Khan, S; Guo, TW; Misra, S; Sci Rep, DOI://10.1038/s41598-018-30293-0 (2018)
A Muscle-Specific Enhancer RNA Mediates Cohesin Recruitment and Regulates Transcription In trans Tsai, PF; Dell'Orso, S; Rodriguez, J et al. Mol. Cell, DOI://10.1016/j.molcel.2018.06.008 (2018)
Effects of Human Sex Chromosome Dosage on Spatial Chromosome Organization Jowhar, Z; Shachar, S; Gudla, PR et al. Mol. Biol. Cell, DOI://10.1091/mbc.E18-06-0359 (2018)
Reliably picking the best endpoint Follmann, D Stat Med, DOI://10.1002/sim.7927 (2018)
A multiprotein supercomplex controlling oncogenic signalling in lymphoma Phelan, JD; Young, RM; Webster, DE et al. Nature, DOI://10.1038/s41586-018-0290-0 (2018)
Glutamatergic Signaling Drives Ketamine-Mediated Response in Depression: Evidence from Dynamic Causal Modeling Gilbert, JR; Yarrington, JS; Wills, KE; Nugent, AC; Zarate, CA; Int. J. Neuropsychopharmacol., DOI://10.1093/ijnp/pyy041 (2018)
Re-analysis of Whole Genome Sequence Data From 279 Ancient Eurasians Reveals Substantial Ancestral Heterogeneity Shriner, D Front Genet, DOI://10.3389/fgene.2018.00268 (2018)
Association of Coffee Drinking With Mortality by Genetic Variation in Caffeine Metabolism: Findings From the UK Biobank Loftfield, E; Cornelis, MC; Caporaso, N; Yu, K; Sinha, R; Freedman, N; JAMA Intern Med, DOI://10.1001/jamainternmed.2018.2425 (2018)
Cone-rod homeobox CRX controls presynaptic active zone formation in photoreceptors of mammalian retina Assawachananont, J; Kim, SY; Kaya, KD; Fariss, R; Roger, JE; Swaroop, A; Hum. Mol. Genet., DOI://10.1093/hmg/ddy272 (2018)

Prediction of CB[8] host-guest binding free energies in SAMPL6 using the double-decoupling method Han, K; Hudson, PS; Jones, MR; Nishikawa, N; Tofoleanu, F; Brooks, BR; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-018-0144-8 (2018)
ATAC2GRN: optimized ATAC-seq and DNase1-seq pipelines for rapid and accurate genome regulatory network inference Pranzatelli, TJF; Michael, DG; Chiorini, JA; BMC Genomics, DOI://10.1186/s12864-018-4943-z (2018)
Modelling the structure of a ceRNA-theoretical, bipartite microRNA-mRNA interaction network regulating intestinal epithelial cellular pathways using R programming Robinson, JM; Henderson, WA; BMC Res Notes, DOI://10.1186/s13104-018-3126-y (2018)
Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse Tubbs, A; Sridharan, S; van Wietmarschen, N et al. Cell, DOI://10.1016/j.cell.2018.07.011 (2018)
Presynaptic Inhibition Selectively Gates Auditory Transmission to the Brainstem Startle Circuit Tabor, KM; Smith, TS; Brown, M; Bergeron, SA; Briggman, KL; Burgess, HA; Curr. Biol., DOI://10.1016/j.cub.2018.06.020 (2018)
Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points Heuston, EF; Keller, CA; Lichtenberg, J et al. Epigenetics Chromatin, DOI://10.1186/s13072-018-0195-z (2018)

Decoding microglia responses to psychosocial stress reveals blood-brain barrier breakdown that may drive stress susceptibility Lehmann, ML; Weigel, TK; Cooper, HA; Elkahloun, AG; Kigar, SL; Herkenham, M; Sci Rep, DOI://10.1038/s41598-018-28737-8 (2018)
A Fast Approximate Algorithm for Mapping Long Reads to Large Reference Databases Jain, C; Dilthey, A; Koren, S; Aluru, S; Phillippy, AM; J. Comput. Biol., DOI://10.1089/cmb.2018.0036 (2018)
Cryo-EM of the dynamin polymer assembled on lipid membrane Kong, L; Sochacki, KA; Wang, H et al. Nature, DOI://10.1038/s41586-018-0378-6 (2018)
Dual Roles for Ikaros in Regulation of Macrophage Chromatin State and Inflammatory Gene Expression Oh, KS; Gottschalk, RA; Lounsbury, NW et al. J. Immunol., DOI://10.4049/jimmunol.1800158 (2018)
Genetic selection of athletic success in sport-hunting dogs Kim, J; Williams, FJ; Dreger, DL et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1800455115 (2018)
NLM at ImageCLEF 2018 Visual Question Answering in the Medical Domain Asma Ben Abacha, Soumya Gayen, Jason J Lau, Sivaramakrishnan Rajaraman, and Dina Demner-Fushman ImageCLEF 2018 (2018)
Scalable Biomedical Image Synthesis with GAN Canas, K; Ubiera, B; Liu, X; Liu Y Proceedings of the Practice and Experience on Advanced Research Computing Article No. 95 , doi://10.1145/3219104.3229261 (2018)
The Energetics and Physiological Impact of Cohesin Extrusion Vian, L; Pekowska, A; Rao, SSP et al. Cell, DOI://10.1016/j.cell.2018.03.072 (2018)
Transcriptional signature primes human oral mucosa for rapid wound healing Iglesias-Bartolome, R; Uchiyama, A; Molinolo, AA et al. Sci Transl Med, DOI://10.1126/scitranslmed.aap8798 (2018)
Efficient experimental designs for isotropic generalized diffusion tensor MRI (IGDTI) Avram, AV; Sarlls, JE; Hutchinson, E; Basser, PJ; Magn Reson Med, DOI://10.1002/mrm.26656 (2018)
Circulating cell-free DNA as a biomarker of tissue injury: Assessment in a cardiac xenotransplantation model Agbor-Enoh, S; Chan, JL; Singh, A et al. J. Heart Lung Transplant., DOI://10.1016/j.healun.2018.04.009 (2018)
PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity van Setten, J; Brody, JA; Jamshidi, Y et al. Nat Commun, DOI://10.1038/s41467-018-04766-9 (2018)

Patient iPSC-derived neural stem cells exhibit phenotypes in concordance with the clinical severity of Mucopolysaccharidosis I Swaroop, M; Brooks, MJ; Gieser, L; Swaroop, A; Zheng, W; Hum. Mol. Genet., DOI://10.1093/hmg/ddy259 (2018)
Genetic diversity of noroviruses circulating in a pediatric cohort in Bangladesh Nelson, MI; Mahfuz, M; Chhabra, P et al. J. Infect. Dis., DOI://10.1093/infdis/jiy454 (2018)
Role of gamma-amino-butyric acid in the dorsal anterior cingulate in age-associated changes in cognition Marenco, S; Meyer, C; van der Veen, JW et al. Neuropsychopharmacology, DOI://10.1038/s41386-018-0134-5 (2018)
Reliability of neural activation and connectivity during implicit face emotion processing in youth Haller, SP; Kircanski, K; Stoddard, J et al. Dev Cogn Neurosci, DOI://10.1016/j.dcn.2018.03.010 (2018)
Frequency of Loss of Function Variants in LRRK2 in Parkinson Disease Blauwendraat, C; Reed, X; Kia, DA et al. JAMA Neurol, DOI://10.1001/jamaneurol.2018.1885 (2018)
ADAM17-Deficient Mice Model the Transcriptional Signature of Human Atopic Dermatitis Woodring, T; Kobayashi, T; Kim, D; Nagao, K; J. Invest. Dermatol., DOI://10.1016/j.jid.2018.04.021 (2018)
Anionic Phospholipids Bind to and Modulate the Activity of Human TRESK Background K+ Channel Giblin, JP; Etayo, I; Castellanos, A; Andres-Bilbe, A; Gasull, X; Mol. Neurobiol., DOI://10.1007/s12035-018-1244-0 (2018)
7 T MRI reveals hippocampal structural abnormalities associated with memory intrusions in childhood-onset schizophrenia Zhou, D; Liu, S; Zhou, X et al. Schizophr. Res., DOI://10.1016/j.schres.2018.07.023 (2018)
BMX-mediated regulation of multiple tyrosine kinases contributes to castration resistance in prostate cancer Chen, S; Cai, C; Sowalsky, AG et al. Cancer Res., DOI://10.1158/0008-5472.CAN-17-3615 (2018)
Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits Haljas, K; Amare, AT; Alizadeh, BZ et al. Psychosom Med, DOI://10.1097/PSY.0000000000000555 (2018)
Hepatitis B virus deregulates cell cycle to promote viral replication and a premalignant phenotype Xia, Y; Cheng, X; Li, Y; Valdez, K; Chen, W; Liang, TJ; J. Virol., DOI://10.1128/JVI.00722-18 (2018)
PfCDPK1 is critical for malaria parasite gametogenesis and mosquito infection Bansal, A; Molina-Cruz, A; Brzostowski, J et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1715443115 (2018)

The major depressive disorder GWAS-supported variant rs10514299 in TMEM161B-MEF2C predicts putamen activation during reward processing in alcohol dependence Muench, C; Schwandt, M; Jung, J; Cortes, CR; Momenan, R; Lohoff, FW; Transl Psychiatry, DOI://10.1038/s41398-018-0184-9 (2018)
Ultra-high resolution blood volume fMRI and BOLD fMRI in humans at 9.4 T: Capabilities and challenges Huber, L; Tse, DHY; Wiggins, CJ et al. Neuroimage, DOI://10.1016/j.neuroimage.2018.06.025 (2018)
Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent Smith, CE; Follis, JL; Dashti, HS et al. Mol Nutr Food Res, DOI://10.1002/mnfr.201700347 (2018)
Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas Campbell, JD; Yau, C; Bowlby, R et al. Cell Rep, DOI://10.1016/j.celrep.2018.03.063 (2018)
Structural analysis of influenza vaccine virus-like particles reveals a multicomponent organization McCraw, DM; Gallagher, JR; Torian, U et al. Sci Rep, DOI://10.1038/s41598-018-28700-7 (2018)
Postnatal developmental dynamics of cell type specification genes in Brn3a/Pou4f1 Retinal Ganglion Cells Muzyka, VV; Brooks, M; Badea, TC; Neural Dev, DOI://10.1186/s13064-018-0110-0 (2018)

The Sleep Inbred Panel, a Collection of Inbred Drosophila melanogaster with Extreme Long and Short Sleep Duration Serrano Negron, YL; Hansen, NF; Harbison, ST; G3 (Bethesda), DOI://10.1534/g3.118.200503 (2018)
Investigation of the seasonal microbiome of Anopheles coluzzii mosquitoes in Mali Krajacich, BJ; Huestis, DL; Dao, A et al. PLoS ONE, DOI://10.1371/journal.pone.0194899 (2018)
Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair Linehan, JL; Harrison, OJ; Han, SJ et al. Cell, DOI://10.1016/j.cell.2017.12.033 (2018)
Influence of gut microbiome on mucosal immune activation and SHIV viral transmission in naive macaques Sui, Y; Dzutsev, A; Venzon, D et al. Mucosal Immunol, DOI://10.1038/s41385-018-0029-0 (2018)
Building Blocks of the Outer Membrane: Calculating a general elastic energy model for β-barrel membrane proteins Lessen, HJ; Fleming, PJ; Fleming, KG; Sodt, AJ; J Chem Theory Comput, DOI://10.1021/acs.jctc.8b00377 (2018)
Strand-specific Dual RNA-seq of Bronchial Epithelial cells Infected with Influenza A/H3N2 Viruses Reveals Splicing of Gene Segment 6 and Novel Host-Virus Interactions Fabozzi, G; Oler, AJ; Liu, P et al. J. Virol., DOI://10.1128/JVI.00518-18 (2018)

Visualizing Deep Learning Activations for Improved Malaria Cell Classification Rajaraman S, Antani SK, Jaeger S Proceedings of Machine Learning Research (PMLR), v69, p40-47 (2018)
Comparing deep learning models for population screening using chest radiography Rajaraman S, Antani SK, Candemir S, Xue Z, Abuya J, Kohli M, Alderson P, Thoma GR Proc. SPIE 10575, Medical Imaging 2018: Computer-Aided Diagn (2018)
The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma Ricketts, CJ; De Cubas, AA; Fan, H et al. Cell Rep, DOI://10.1016/j.celrep.2018.06.032 (2018)
NCR+ ILC3 maintain larger STAT4 reservoir via T-BET to regulate type 1 features upon IL-23 stimulation in mice Mikami, Y; Scarno, G; Zitti, B et al. Eur. J. Immunol., DOI://10.1002/eji.201847480 (2018)
Parameterization of the CHARMM All-Atom Force Field for Ether Lipids and Model Linear Ethers Leonard, AN; Pastor, RW; Klauda, JB; J Phys Chem B, DOI://10.1021/acs.jpcb.8b02743 (2018)
MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma Yohe, ME; Gryder, BE; Shern, JF et al. Sci Transl Med, DOI://10.1126/scitranslmed.aan4470 (2018)
Integrative Bayesian Analysis Identifies Rhabdomyosarcoma Disease Genes Xu, L; Zheng, Y; Liu, J et al. Cell Rep, DOI://10.1016/j.celrep.2018.06.006 (2018)
Geographic clonal tracking in macaques provides insights into HSPC migration and differentiation Wu, C; Espinoza, DA; Koelle, SJ et al. J. Exp. Med., DOI://10.1084/jem.20171341 (2018)
An epigenetic mechanism for cavefish eye degeneration Gore, AV; Tomins, KA; Iben, J et al. Nat Ecol Evol, DOI://10.1038/s41559-018-0569-4 (2018)
N-Myc Downstream-Regulated Gene 1 Restricts Hepatitis C Virus Propagation by Regulating Lipid Droplet Biogenesis and Viral Assembly Schweitzer, CJ; Zhang, F; Boyer, A; Valdez, K; Cam, M; Liang, TJ; J. Virol., DOI://10.1128/JVI.01166-17 (2018)
Arl2-Mediated Allosteric Release of Farnesylated KRas4B from Shuttling Factor PDEδ Ozdemir, ES; Jang, H; Gursoy, A; Keskin, O; Nussinov, R; J Phys Chem B, DOI://10.1021/acs.jpcb.8b04347 (2018)
Defects in the Alternative Splicing-Dependent Regulation of REST Cause Deafness Nakano, Y; Kelly, MC; Rehman, AU et al. Cell, DOI://10.1016/j.cell.2018.06.004 (2018)

Targeting Notch1 and IKKa enhanced NF-κB activation in CD133+ Skin Cancer Stem Cells Quan, XX; Voong Hawk, N; Chen, W et al. Mol. Cancer Ther., DOI://10.1158/1535-7163.MCT-17-0421 (2018)
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein Kang, Y; Kuybeda, O; de Waal, PW et al. Nature, DOI://10.1038/s41586-018-0215-y (2018)
An Autonomic Network: Synchrony Between Slow Rhythms of Pulse and Brain Resting State Is Associated with Personality and Emotions Shokri-Kojori, E; Tomasi, D; Volkow, ND; Cereb. Cortex, DOI://10.1093/cercor/bhy144 (2018)
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries Feitosa, MF; Kraja, AT; Chasman, DI et al. PLoS ONE, DOI://10.1371/journal.pone.0198166 (2018)
Morphometric analysis and neuroanatomical mapping of the zebrafish brain Gupta, T; Marquart, GD; Horstick, EJ; Tabor, KM; Pajevic, S; Burgess, HA; Methods, DOI://10.1016/j.ymeth.2018.06.008 (2018)
Guide RNA selection for CRISPR-Cas9 transfections in Plasmodium falciparum Ribeiro, JM; Garriga, M; Potchen, N et al. Int. J. Parasitol., DOI://10.1016/j.ijpara.2018.03.009 (2018)

Neoadjuvant-intensive androgen deprivation therapy selects for prostate tumor foci with diverse subclonal oncogenic alterations Sowalsky, AG; Ye, H; Bhasin, M et al. Cancer Res., DOI://10.1158/0008-5472.CAN-18-0610 (2018)
Late manifestation of alloantibody-associated injury and clinical pulmonary antibody-mediated rejection: Evidence from cell-free DNA analysis Agbor-Enoh, S; Jackson, AM; Tunc, I et al. J. Heart Lung Transplant., DOI://10.1016/j.healun.2018.01.1305 (2018)
A subregion-based burden test for simultaneous identification of susceptibility loci and subregions within Zhu, B; Mirabello, L; Chatterjee, N; Genet. Epidemiol., DOI://10.1002/gepi.22134 (2018)
HPV integration hijacks and multimerizes a cellular enhancer to generate a viral-cellular super-enhancer that drives high viral oncogene expression Warburton, A; Redmond, CJ; Dooley, KE et al. PLoS Genet., DOI://10.1371/journal.pgen.1007179 (2018)
Publisher Correction: Cryo-EM structure of human rhodopsin bound to an inhibitory G protein Kang, Y; Kuybeda, O; de Waal, PW et al. Nature, DOI://10.1038/s41586-018-0302-0 (2018)
Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma Schmitz, R; Wright, GW; Huang, DW et al. N. Engl. J. Med., DOI://10.1056/NEJMoa1801445 (2018)

ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming Mishra, P; Tang, W; Putluri, V et al. J. Clin. Invest., DOI://10.1172/JCI93815 (2018)
Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay Duverger, O; Carlson, JC; Karacz, CM et al. PLoS Genet., DOI://10.1371/journal.pgen.1007168 (2018)
Innate and adaptive lymphocytes sequentially shape the gut microbiota and lipid metabolism Mao, K; Baptista, AP; Tamoutounour, S et al. Nature, DOI://10.1038/nature25437 (2018)
Normative brain size variation and brain shape diversity in humans Reardon, PK; Seidlitz, J; Vandekar, S et al. Science, DOI://10.1126/science.aar2578 (2018)
Microbiology catches the cryo-EM bug Earl, LA; Falconieri, V; Subramaniam, S; Curr. Opin. Microbiol., DOI://10.1016/j.mib.2018.02.012 (2018)
RiboSketch: Versatile Visualization of Multi-stranded RNA and DNA Secondary Structure Lu, JS; Bindewald, E; Kasprzak, W; Shapiro, BA; Bioinformatics, DOI://10.1093/bioinformatics/bty468 (2018)

Sialome diversity of ticks revealed by RNAseq of single tick salivary glands Perner, J; Kropáčková, S; Kopáček, P; Ribeiro, JMC; PLoS Negl Trop Dis, DOI://10.1371/journal.pntd.0006410 (2018)
Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density Alonso, N; Estrada, K; Albagha, OME et al. Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2017-212469 (2018)
Structure-Guided Modification of Heterocyclic Antagonists of the P2Y14 Receptor Yu, J; Ciancetta, A; Dudas, S; Duca, S; Lottermoser, J; Jacobson, KA; J. Med. Chem., DOI://10.1021/acs.jmedchem.8b00168 (2018)
A coupled-clock system drives the automaticity of human sinoatrial nodal pacemaker cells Tsutsui, K; Monfredi, OJ; Sirenko-Tagirova, SG et al. Sci Signal, DOI://10.1126/scisignal.aap7608 (2018)
The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma McBride, MJ; Pulice, JL; Beird, HC et al. Cancer Cell, DOI://10.1016/j.ccell.2018.05.002 (2018)
AptaSUITE: A Full-Featured Bioinformatics Framework for the Comprehensive Analysis of Aptamers from HT-SELEX Experiments Hoinka, J; Backofen, R; Przytycka, TM; Mol Ther Nucleic Acids, DOI://10.1016/j.omtn.2018.04.006 (2018)

Modifier locus mapping of a transgenic F2 mouse population identifies CCDC115 as a novel aggressive prostate cancer modifier gene in humans Winter, JM; Curry, NL; Gildea, DM et al. BMC Genomics, DOI://10.1186/s12864-018-4827-2 (2018)
Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers Hodges, HC; Stanton, BZ; Cermakova, K et al. Nat. Struct. Mol. Biol., DOI://10.1038/s41594-017-0007-3 (2018)
Exploring Substrate Binding in the Extracellular Vestibule of MhsT by Atomistic Simulations and Markov Models Abramyan, AM; Quick, M; Xue, C; Javitch, JA; Shi, L; J Chem Inf Model, DOI://10.1021/acs.jcim.8b00175 (2018)
HiCTMap: Detection and analysis of chromosome territory structure and position by high-throughput imaging Jowhar, Z; Gudla, PR; Shachar, S et al. Methods, DOI://10.1016/j.ymeth.2018.01.013 (2018)
Chromatic: WebAssembly-Based Cancer Genome Viewer Finney, R; Meerzaman, D; Cancer Inform, DOI://10.1177/1176935118771972 (2018)
DNA Methylation and Regulatory Elements during Chicken Germline Stem Cell Differentiation He, Y; Zuo, Q; Edwards, J et al. Stem Cell Reports, DOI://10.1016/j.stemcr.2018.03.018 (2018)

Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer Zacharakis, N; Chinnasamy, H; Black, M et al. Nat. Med., DOI://10.1038/s41591-018-0040-8 (2018)
Cracking the DNA Code for V(D)J Recombination Kim, MS; Chuenchor, W; Chen, X et al. Mol. Cell, DOI://10.1016/j.molcel.2018.03.008 (2018)
Evaluation and comparison of predictive individual-level general surrogates Gabriel, EE; Sachs, MC; Halloran, ME; Biostatistics, DOI://10.1093/biostatistics/kxx037 (2018)
DLX3-Dependent STAT3 Signaling in Keratinocytes Regulates Skin Immune Homeostasis Bhattacharya, S; Kim, JC; Ogawa, Y et al. J. Invest. Dermatol., DOI://10.1016/j.jid.2017.11.033 (2018)
Rapid Classification and Identification of Multiple Microorganisms with Accurate Statistical Significance via High-Resolution Tandem Mass Spectrometry Alves, G; Wang, G; Ogurtsov, AY et al. J. Am. Soc. Mass Spectrom., DOI://10.1007/s13361-018-1986-y (2018)
Emergence and Evolution of Novel Reassortant Influenza A Viruses in Canines in Southern China Chen, Y; Trovão, NS; Wang, G et al. MBio, DOI://10.1128/mBio.00909-18 (2018)
Multivalent Display Using Hybrid Virus Nanoparticles Brown, SD Methods Mol. Biol., DOI://10.1007/978-1-4939-7893-9_10 (2018)
In-depth investigations of adolescents and adults with holoprosencephaly identify unique characteristics Weiss, K; Kruszka, P; Guillen Sacoto, MJ et al. Genet. Med., DOI://10.1038/gim.2017.68 (2018)
Correction: Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations Liang, J; Le, TH; Velez Edwards, DR et al. PLoS Genet., DOI://10.1371/journal.pgen.1007345 (2018)
Genome-Wide Mapping of DNA Accessibility and Binding Sites for CREB and C/EBPβ in Vasopressin-Sensitive Collecting Duct Cells Jung, HJ; Raghuram, V; Lee, JW; Knepper, MA; J. Am. Soc. Nephrol., DOI://10.1681/ASN.2017050545 (2018)
Discovering a binary CTCF code with a little help from BORIS Lobanenkov, VV; Zentner, GE; Nucleus, DOI://10.1080/19491034.2017.1394536 (2018)
T-cell responses to TP53 "hotspot" mutations and unique neoantigens expressed by human ovarian cancers Deniger, DC; Pasetto, A; Robbins, PF et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-0573 (2018)

Computational Modeling of Mitochondrial Function from a Systems Biology Perspective Cortassa, S; Sollott, SJ; Aon, MA; Methods Mol. Biol., DOI://10.1007/978-1-4939-7831-1_14 (2018)
Trait paranoia shapes inter-subject synchrony in brain activity during an ambiguous social narrative Finn, ES; Corlett, PR; Chen, G; Bandettini, PA; Constable, RT; Nat Commun, DOI://10.1038/s41467-018-04387-2 (2018)
High burden of birthweight-lowering genetic variants in Africans and Asians Tekola-Ayele, F; Workalemahu, T; Amare, AT; BMC Med, DOI://10.1186/s12916-018-1061-3 (2018)
SWI/SNF and RSC cooperate to reposition and evict promoter nucleosomes at highly expressed genes in yeast Rawal, Y; Chereji, RV; Qiu, H et al. Genes Dev., DOI://10.1101/gad.312850.118 (2018)
Comparative Population Genomics Analysis of the Mammalian Fungal Pathogen Pneumocystis Cissé, OH; Ma, L; Wei Huang, D et al. MBio, DOI://10.1128/mBio.00381-18 (2018)
Characterization of Hemagglutinin Antigens on Influenza Virus and within Vaccines Using Electron Microscopy Gallagher, JR; McCraw, DM; Torian, U et al. Vaccines (Basel), DOI://10.3390/vaccines6020031 (2018)

Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence Vera-Ramirez, L; Vodnala, SK; Nini, R; Hunter, KW; Green, JE; Nat Commun, DOI://10.1038/s41467-018-04070-6 (2018)
Variation in human chromosome 21 ribosomal RNA genes characterized by TAR cloning and long-read sequencing Kim, JH; Dilthey, AT; Nagaraja, R et al. Nucleic Acids Res., DOI://10.1093/nar/gky442 (2018)
Clinically Relevant Cytotoxic Immune Cell Signatures and Clonal Expansion of T-Cell Receptors in High-risk MYCN-not-amplified Human Neuroblastoma Wei, JS; Kuznetsov, IB; Zhang, S et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-18-0599 (2018)
Functional screening of FGFR4-driven tumorigenesis identifies PI3K/mTOR inhibition as a therapeutic strategy in rhabdomyosarcoma McKinnon, T; Venier, R; Yohe, M et al. Oncogene, DOI://10.1038/s41388-017-0122-y (2018)
Graph-Theoretic Analysis of Monomethyl Phosphate Clustering in Ionic Solutions Han, K; Venable, RM; Bryant, AM et al. J Phys Chem B, DOI://10.1021/acs.jpcb.7b10730 (2018)
Atomic Resolution Cryo-EM Structure of β-Galactosidase Bartesaghi, A; Aguerrebere, C; Falconieri, V et al. Structure, DOI://10.1016/j.str.2018.04.004 (2018)
Identification of Novel Targets for Lung Cancer Therapy Using an Induced Pluripotent Stem Cell Model Shukla, V; Rao, M; Zhang, H et al. Ann Am Thorac Soc, DOI://10.1513/AnnalsATS.201707-610MG (2018)
The distinct structural preferences of tau protein repeat domains Li, X; Dong, X; Wei, G; Margittai, M; Nussinov, R; Ma, B; Chem. Commun. (Camb.), DOI://10.1039/c8cc01263f (2018)
Neutrophil subsets and their gene signature associate with vascular inflammation and coronary atherosclerosis in lupus Carlucci, PM; Purmalek, MM; Dey, AK et al. JCI Insight, DOI://10.1172/jci.insight.99276 (2018)
Molecular dynamics simulations of lipid nanodiscs Pourmousa, M; Pastor, RW; Biochim. Biophys. Acta, DOI://10.1016/j.bbamem.2018.04.015 (2018)
Epigenome-Wide Association Study of Soluble Tumor Necrosis Factor Receptor 2 Levels in the Framingham Heart Study Mendelson, MM; Johannes, R; Liu, C et al. Front Pharmacol, DOI://10.3389/fphar.2018.00207 (2018)
Experimental and Computational Protocols for Studies of Cross-Seeding Amyloid Assemblies Ren, B; Hu, R; Zhang, M et al. Methods Mol. Biol., DOI://10.1007/978-1-4939-7811-3_27 (2018)

Replica Exchange Molecular Dynamics: A Practical Application Protocol with Solutions to Common Problems and a Peptide Aggregation and Self-Assembly Example Qi, R; Wei, G; Ma, B; Nussinov, R; Methods Mol. Biol., DOI://10.1007/978-1-4939-7811-3_5 (2018)
Dynamic Behavior of RNA Nanoparticles Analyzed by AFM on a Mica/Air Interface Sajja, S; Chandler, M; Fedorov, D et al. Langmuir, DOI://10.1021/acs.langmuir.8b00105 (2018)
iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications Ou, J; Ball, JM; Luan, Y et al. Cell, DOI://10.1016/j.cell.2018.03.010 (2018)
Germline gain-of-function myeloid differentiation primary response gene-88 (MYD88) mutation in a child with severe arthritis Sikora, KA; Bennett, JR; Vyncke, L et al. J. Allergy Clin. Immunol., DOI://10.1016/j.jaci.2018.01.027 (2018)
Iron homeostasis regulates facultative heterochromatin assembly in adaptive genome control Gallagher, PS; Larkin, M; Thillainadesan, G et al. Nat. Struct. Mol. Biol., DOI://10.1038/s41594-018-0056-2 (2018)
Whole-Exome Sequencing to Identify Rare Variants and Gene Networks That Increase Susceptibility to Scleroderma in African Americans Gourh, P; Remmers, EF; Boyden, SE et al. , DOI://10.1002/art.40541 (2018)

Irritability Trajectories, Cortical Thickness, and Clinical Outcomes in a Sample Enriched for Preschool Depression Pagliaccio, D; Pine, DS; Barch, DM; Luby, JL; Leibenluft, E; J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2018.02.010 (2018)
Temporal Variability of Oral Microbiota over 10 Months and the Implications for Future Epidemiologic Studies Vogtmann, E; Hua, X; Zhou, L et al. Cancer Epidemiol. Biomarkers Prev., DOI://10.1158/1055-9965.EPI-17-1004 (2018)
Position-specific intron retention is mediated by the histone methyltransferase SDG725 Wei, G; Liu, K; Shen, T et al. BMC Biol., DOI://10.1186/s12915-018-0513-8 (2018)
Day length is associated with physical activity and sedentary behavior among older women Schepps, MA; Shiroma, EJ; Kamada, M; Harris, TB; Lee, IM; Sci Rep, DOI://10.1038/s41598-018-25145-w (2018)
Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group Hibar, DP; Westlye, LT; Doan, NT et al. Mol. Psychiatry, DOI://10.1038/mp.2017.73 (2018)
A draft genome sequence for the Ixodes scapularis cell line, ISE6 Miller, JR; Koren, S; Dilley, KA et al. F1000Res, DOI://10.12688/f1000research.13635.1 (2018)

Insulin promoter in human pancreatic β cells contacts diabetes susceptibility loci and regulates genes affecting insulin metabolism Jian, X; Felsenfeld, G; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1803146115 (2018)
Organization of the core respiratory network: Insights from optogenetic and modeling studies Ausborn, J; Koizumi, H; Barnett, WH et al. PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1006148 (2018)
Dealing with competing risks in clinical trials: How to choose the primary efficacy analysis Troendle, JF; Leifer, ES; Kunz, L; Stat Med, DOI://10.1002/sim.7800 (2018)
A cleavage product of Polycystin-1 is a mitochondrial matrix protein that affects mitochondria morphology and function when heterologously expressed Lin, CC; Kurashige, M; Liu, Y et al. Sci Rep, DOI://10.1038/s41598-018-20856-6 (2018)
SIRT1 is a transcriptional enhancer of the glucocorticoid receptor acting independently to its deacetylase activity Suzuki, S; Iben, JR; Coon, SL; Kino, T; Mol. Cell. Endocrinol., DOI://10.1016/j.mce.2017.09.012 (2018)
Massively Parallel Single Nucleus Transcriptional Profiling Defines Spinal Cord Neurons and Their Activity during Behavior Sathyamurthy, A; Johnson, KR; Matson, KJE et al. Cell Rep, DOI://10.1016/j.celrep.2018.02.003 (2018)
A mutational comparison of adult and adolescent and young adult (AYA) colon cancer Tricoli, JV; Boardman, LA; Patidar, R et al. Cancer, DOI://10.1002/cncr.31136 (2018)
Insufficient evidence for pathogenicity of SNCA His50Gln (H50Q) in Parkinson's disease Blauwendraat, C; Kia, DA; Pihlstrøm, L et al. Neurobiol. Aging, DOI://10.1016/j.neurobiolaging.2017.12.012 (2018)
Comprehensive Synthesis of Amino Acid-Derived Thiazole Peptidomimetic Analogues to Understand the Enigmatic Drug/Substrate-Binding Site of P-Glycoprotein Patel, BA; Abel, B; Barbuti, AM et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.7b01340 (2018)
Homeobox transcription factor DLX4 is not necessary for skin development and homeostasis Bhattacharya, S; Duverger, O; Brooks, SR; Morasso, MI; Exp. Dermatol., DOI://10.1111/exd.13503 (2018)
Outcomes of Children and Adolescents with Advanced Hereditary Medullary Thyroid Carcinoma Treated with Vandetanib Kraft, IL; Akshintala, S; Zhu, Y et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-17-2101 (2018)
Feedforward Inhibition Allows Input Summation to Vary in Recurrent Cortical Networks Histed, MH eNeuro, DOI://10.1523/ENEURO.0356-17.2018 (2018)

Effects on gene expression and behavior of untagged short tandem repeats: the case of arginine vasopressin receptor 1a (AVPR1a) and externalizing behaviors Landefeld, CC; Hodgkinson, CA; Spagnolo, PA et al. Transl Psychiatry, DOI://10.1038/s41398-018-0120-z (2018)
Morphometric Similarity Networks Detect Microscale Cortical Organization and Predict Inter-Individual Cognitive Variation Seidlitz, J; Váša, F; Shinn, M et al. Neuron, DOI://10.1016/j.neuron.2017.11.039 (2018)
A multicohort, longitudinal study of cerebellar development in attention deficit hyperactivity disorder Shaw, P; Ishii-Takahashi, A; Park, MT et al. J Child Psychol Psychiatry, DOI://10.1111/jcpp.12920 (2018)
Single-tubule RNA-Seq uncovers signaling mechanisms that defend against hyponatremia in SIADH Lee, JW; Alsady, M; Chou, CL et al. Kidney Int., DOI://10.1016/j.kint.2017.06.008 (2018)
Interrogating the Functions of PRDM9 Domains in Meiosis Thibault-Sennett, S; Yu, Q; Smagulova, F et al. Genetics, DOI://10.1534/genetics.118.300565 (2018)
Using standard microbiome reference groups to simplify beta-diversity analyses and facilitate independent validation Maziarz, M; Pfeiffer, RM; Wan, Y; Gail, MH; Bioinformatics, DOI://10.1093/bioinformatics/bty297 (2018)

Electrophysiological heterogeneity of pacemaker cells in the rabbit intercaval region, including the SA node: insights from recording multiple ion currents in each cell Monfredi, O; Tsutsui, K; Ziman, B; Stern, MD; Lakatta, EG; Maltsev, VA; Am. J. Physiol. Heart Circ. Physiol., DOI://10.1152/ajpheart.00253.2016 (2018)
Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors Giannelou, A; Wang, H; Zhou, Q et al. Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2017-212401 (2018)
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay Baird, TD; Cheng, KC; Chen, YC et al. Elife, DOI://10.7554/eLife.33178 (2018)
Somatic activating mutations in MAP2K1 cause melorheostosis Kang, H; Jha, S; Deng, Z et al. Nat Commun, DOI://10.1038/s41467-018-03720-z (2018)
Analysis of the 9p21.3 sequence associated with coronary artery disease reveals a tendency for duplication in a CAD patient Kouprina, N; Liskovykh, M; Lee, NCO et al. Oncotarget, DOI://10.18632/oncotarget.24567 (2018)
Characterization of clinically used oral antiseptics as quadruplex-binding ligands Calabrese, DR; Zlotkowski, K; Alden, S et al. Nucleic Acids Res., DOI://10.1093/nar/gky084 (2018)

A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope Zhou, T; Zheng, A; Baxa, U et al. Immunity, DOI://10.1016/j.immuni.2018.02.013 (2018)
Statistical power comparisons at 3T and 7T with a GO / NOGO task Torrisi, S; Chen, G; Glen, D et al. Neuroimage, DOI://10.1016/j.neuroimage.2018.03.071 (2018)
Gcn4 Binding in Coding Regions Can Activate Internal and Canonical 5' Promoters in Yeast Rawal, Y; Chereji, RV; Valabhoju, V et al. Mol. Cell, DOI://10.1016/j.molcel.2018.03.007 (2018)
Deep sequencing of the mitochondrial genome reveals common heteroplasmic sites in NADH dehydrogenase genes Liu, C; Fetterman, JL; Liu, P et al. Hum. Genet., DOI://10.1007/s00439-018-1873-4 (2018)
A Latent Variable Approach to Differentiating Neural Mechanisms of Irritability and Anxiety in Youth Kircanski, K; White, LK; Tseng, WL et al. JAMA Psychiatry, DOI://10.1001/jamapsychiatry.2018.0468 (2018)
The impact of aging on primate hematopoiesis as interrogated by clonal tracking Yu, KR; Espinoza, DA; Wu, C et al. Blood, DOI://10.1182/blood-2017-08-802033 (2018)

Inferring properties of disordered chains from FRET transfer efficiencies Zheng, W; Zerze, GH; Borgia, A; Mittal, J; Schuler, B; Best, RB; J Chem Phys, DOI://10.1063/1.5006954 (2018)
A Novel Method to Extend a Partial-Body CT for the Reconstruction of Dose to Organs beyond the Scan Range Kuzmin, GA; Mille, MM; Jung, JW et al. Radiat. Res., DOI://10.1667/RR14999.1 (2018)
Association of Methylation Signals With Incident Coronary Heart Disease in an Epigenome-Wide Assessment of Circulating Tumor Necrosis Factor α Aslibekyan, S; Agha, G; Colicino, E et al. JAMA Cardiol, DOI://10.1001/jamacardio.2018.0510 (2018)
A method for determining haploid and triploid genotypes and their association with vascular phenotypes in Williams syndrome and 7q11.23 duplication syndrome Gregory, MD; Kolachana, B; Yao, Y et al. BMC Med. Genet., DOI://10.1186/s12881-018-0563-3 (2018)
IL1RN Variation Influences both Disease Susceptibility and Response to Human Recombinant IL-1RA Therapy in Systemic Juvenile Idiopathic Arthritis Arthur, VL; Shuldiner, E; Remmers, EF et al. , DOI://10.1002/art.40498 (2018)
Genome-wide Analyses Identify KIF5A as a Novel ALS Gene Nicolas, A; Kenna, KP; Renton, AE et al. Neuron, DOI://10.1016/j.neuron.2018.02.027 (2018)

Emollient use alters skin barrier and microbes in infants at risk for developing atopic dermatitis Glatz, M; Jo, JH; Kennedy, EA et al. PLoS ONE, DOI://10.1371/journal.pone.0192443 (2018)
Quantification of Human Microbiome Stability Over Six Months: Implications for Epidemiologic Studies Sinha, R; Goedert, JJ; Vogtmann, E et al. Am. J. Epidemiol., DOI://10.1093/aje/kwy064 (2018)
A trapped human PPM1A-phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity Debnath, S; Kosek, D; Tagad, HD et al. J. Biol. Chem., DOI://10.1074/jbc.RA117.001213 (2018)
Default Mode Connectivity in Major Depressive Disorder Measured Up to 10 Days After Ketamine Administration Evans, JW; Szczepanik, J; Brutsché, N; Park, LT; Nugent, AC; Zarate, CA; Biol. Psychiatry, DOI://10.1016/j.biopsych.2018.01.027 (2018)
An Extended Guinier Analysis for Intrinsically Disordered Proteins Zheng, W; Best, RB; J. Mol. Biol., DOI://10.1016/j.jmb.2018.03.007 (2018)
ZFR coordinates crosstalk between RNA decay and transcription in innate immunity Haque, N; Ouda, R; Chen, C; Ozato, K; Hogg, JR; Nat Commun, DOI://10.1038/s41467-018-03326-5 (2018)
Lifestyle, metabolite, and genetic determinants of formate concentrations in a cross-sectional study in young, healthy adults Brosnan, JT; Mills, JL; Ueland, PM et al. Am. J. Clin. Nutr., DOI://10.1093/ajcn/nqx065 (2018)
Shep regulates Drosophila neuronal remodeling by controlling transcription of its chromatin targets Chen, D; Dale, RK; Lei, EP; Development, DOI://10.1242/dev.154047 (2018)
Balancing Force Field Protein-Lipid Interactions To Capture Transmembrane Helix-Helix Association Domanski, J; Sansom, MSP; Stansfeld, PJ; Best, RB; J Chem Theory Comput, DOI://10.1021/acs.jctc.7b00983 (2018)
Metabolic profiles of triple-negative and luminal A breast cancer subtypes in African-American identify key metabolic differences Tayyari, F; Gowda, GAN; Olopade, OF et al. Oncotarget, DOI://10.18632/oncotarget.24433 (2018)
Targeting loss of the Hippo signaling pathway in NF2-deficient papillary kidney cancers Sourbier, C; Liao, PJ; Ricketts, CJ et al. Oncotarget, DOI://10.18632/oncotarget.24112 (2018)
Gestational cytokine concentrations and neurocognitive development at 7 years Ghassabian, A; Albert, PS; Hornig, M et al. Transl Psychiatry, DOI://10.1038/s41398-018-0112-z (2018)

LMTK3 confers chemo-resistance in breast cancer Stebbing, J; Shah, K; Lit, LC et al. Oncogene, DOI://10.1038/s41388-018-0197-0 (2018)
Argonaute2 and LaminB modulate gene expression by controlling chromatin topology Nazer, E; Dale, RK; Chinen, M; Radmanesh, B; Lei, EP; PLoS Genet., DOI://10.1371/journal.pgen.1007276 (2018)
A deep insight into the male and female sialotranscriptome of adult Culex tarsalis mosquitoes Ribeiro, JMC; Martin-Martin, I; Moreira, FR; Bernard, KA; Calvo, E; Insect Biochem. Mol. Biol., DOI://10.1016/j.ibmb.2018.03.001 (2018)
In Vitro Modeling of Human Germ Cell Development Using Pluripotent Stem Cells Zhao, Y; Ye, S; Liang, D et al. Stem Cell Reports, DOI://10.1016/j.stemcr.2018.01.001 (2018)
Evidence of subgroups in smokers as revealed in clinical measures and evaluated by neuroimaging data: a preliminary study Ding, X; Salmeron, BJ; Wang, J; Yang, Y; Stein, EA; Ross, TJ; Addict Biol, DOI://10.1111/adb.12620 (2018)
Co-evolutionary fitness landscapes for sequence design Tian, P; Louis, JM; Baber, JL; Aniana, A; Best, R; Angew. Chem. Int. Ed. Engl., DOI://10.1002/anie.201713220 (2018)

An Efficient Single-Cell RNA-Seq Approach to Identify Neoantigen-Specific T Cell Receptors Lu, YC; Zheng, Z; Robbins, PF et al. Mol. Ther., DOI://10.1016/j.ymthe.2017.10.018 (2018)
Mechanism of Darunavir (DRV)'s High Genetic Barrier to HIV-1 Resistance: A Key V32I Substitution in Protease Rarely Occurs, but Once It Occurs, It Predisposes HIV-1 To Develop DRV Resistance Aoki, M; Das, D; Hayashi, H et al. MBio, DOI://10.1128/mBio.02425-17 (2018)
Nanopore sequencing and assembly of a human genome with ultra-long reads Jain, M; Koren, S; Miga, KH et al. Nat. Biotechnol., DOI://10.1038/nbt.4060 (2018)
Impact of time-of-day on diffusivity measures of brain tissue derived from diffusion tensor imaging Thomas, C; Sadeghi, N; Nayak, A et al. Neuroimage, DOI://10.1016/j.neuroimage.2018.02.026 (2018)
Verdazyl-ribose: A new radical for solid-state dynamic nuclear polarization at high magnetic field Thurber, KR; Le, TN; Changcoco, V; Brook, DJR; J. Magn. Reson., DOI://10.1016/j.jmr.2018.02.016 (2018)
Minoxidil improves vascular compliance, restores cerebral blood flow and alters extracellular matrix gene expression in a model of chronic vascular stiffness Knutsen, R; Beeman, SC; Broekelmann, TJ et al. Am. J. Physiol. Heart Circ. Physiol., DOI://10.1152/ajpheart.00683.2017 (2018)

An insight into the salivary gland and fat body transcriptome of Panstrongylus lignarius (Hemiptera: Heteroptera), the main vector of Chagas disease in Peru Nevoa, JC; Mendes, MT; da Silva, MV; Soares, SC; Oliveira, CJF; Ribeiro, JMC; PLoS Negl Trop Dis, DOI://10.1371/journal.pntd.0006243 (2018)
Highly Disordered Amyloid-β Monomer Probed by Single-Molecule FRET and MD Simulation Meng, F; Bellaiche, MMJ; Kim, JY; Zerze, GH; Best, RB; Chung, HS; Biophys. J., DOI://10.1016/j.bpj.2017.12.025 (2018)
Identification of Casz1 as a Regulatory Protein Controlling T Helper Cell Differentiation, Inflammation, and Immunity Bhaskaran, N; Liu, Z; Saravanamuthu, SS et al. Front Immunol, DOI://10.3389/fimmu.2018.00184 (2018)
GRL-079, a Novel HIV-1 Protease Inhibitor, Is Extremely Potent against Multidrug-Resistant HIV-1 Variants and Has a High Genetic Barrier against the Emergence of Resistant Variants Delino NS, Aoki M, Hayashi H, Hattori SI, Chang SB, Takamatsu Y, Martyr CD, Das D, Ghosh AK, Mitsuya H Antimicrob Agents Chemother. , doi: 10.1128/AAC.02060-17 (2018)
Design and statistical considerations for studies evaluating the efficacy of a single dose of the human papillomavirus (HPV) vaccine Sampson, JN; Hildesheim, A; Herrero, R; Gonzalez, P; Kreimer, A; Gail, MH; Contemp Clin Trials, DOI://10.1016/j.cct.2018.02.010 (2018)
Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas Cobo, I; Martinelli, P; Flández, M et al. Nature, DOI://10.1038/nature25751 (2018)

Estimating recurrence and incidence of preterm birth subject to measurement error in gestational age: A hidden Markov modeling approach Albert, PS Stat Med, DOI://10.1002/sim.7624 (2018)
Extreme disorder in an ultrahigh-affinity protein complex Borgia, A; Borgia, MB; Bugge, K et al. Nature, DOI://10.1038/nature25762 (2018)
Epigenome comparisons reveal linkage between gene expression and postnatal remodeling of chromatin domain topology Howard, BH; Hirai, TH; Russanova, VR; PLoS ONE, DOI://10.1371/journal.pone.0191033 (2018)
Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells Hu, G; Cui, K; Fang, D et al. Immunity, DOI://10.1016/j.immuni.2018.01.013 (2018)
Structural Modulation of Human Amylin Protofilaments by Naturally Occurring Mutations Tofoleanu, F; Yuan, Y; Pickard, FC; Tywoniuk, B; Brooks, BR; Buchete, NV; J Phys Chem B, DOI://10.1021/acs.jpcb.7b12083 (2018)
Assessment of PCXMC for patients with different body size in chest and abdominal x ray examinations: a Monte Carlo simulation study Borrego, D; Lowe, EM; Kitahara, CM; Lee, C; Phys Med Biol, DOI://10.1088/1361-6560/aab13e (2018)

Dose coefficients for children and young adolescents exposed to external neutron fields Griffin, KT; Mille, M; Lee, C; J Radiol Prot, DOI://10.1088/1361-6498/aab126 (2018)
CD63, MHC class 1, and CD47 identify subsets of extracellular vesicles containing distinct populations of noncoding RNAs Kaur, S; Elkahloun, AG; Arakelyan, A et al. Sci Rep, DOI://10.1038/s41598-018-20936-7 (2018)
Transient Receptor Potential Channels TRPM4 and TRPC3 Critically Contribute to Respiratory Motor Pattern Formation but not Rhythmogenesis in Rodent Brainstem Circuits Koizumi, H; John, TT; Chia, JX et al. eNeuro, DOI://10.1523/ENEURO.0332-17.2018 (2018)
Ridding fMRI data of motion-related influences: Removal of signals with distinct spatial and physical bases in multiecho data Power, JD; Plitt, M; Gotts, SJ et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1720985115 (2018)
The Antimicrobial Peptide CRAMP Is Essential for Colon Homeostasis by Maintaining Microbiota Balance Yoshimura, T; McLean, MH; Dzutsev, AK et al. J. Immunol., DOI://10.4049/jimmunol.1602073 (2018)
Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of Bacterial Plasmids Conferring Carbapenem Resistance Weingarten, RA; Johnson, RC; Conlan, S et al. MBio, DOI://10.1128/mBio.02011-17 (2018)

5-Azacytidine prevents relapse and produces long-term complete remissions in leukemia xenografts treated with Moxetumomab pasudotox Müller, F; Cunningham, T; Stookey, S et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1714512115 (2018)
Raf-1 Cysteine-Rich Domain Increases the Affinity of K-Ras/Raf at the Membrane, Promoting MAPK Signaling Li, S; Jang, H; Zhang, J; Nussinov, R; Structure, DOI://10.1016/j.str.2018.01.011 (2018)
Global changes of H3K27me3 domains and Polycomb group protein distribution in the absence of recruiters Spps or Pho Brown, JL; Sun, MA; Kassis, JA; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1716299115 (2018)
Precise genome-wide mapping of single nucleosomes and linkers in vivo Chereji, RV; Ramachandran, S; Bryson, TD; Henikoff, S; Genome Biol., DOI://10.1186/s13059-018-1398-0 (2018)
Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer Klein, AP; Wolpin, BM; Risch, HA et al. Nat Commun, DOI://10.1038/s41467-018-02942-5 (2018)
The klotho-related protein KLPH (lctl) has preferred expression in lens and is essential for expression of clic5 and normal lens suture formation Fan, J; Lerner, J; Wyatt, MK et al. Exp. Eye Res., DOI://10.1016/j.exer.2018.02.001 (2018)
Self-reported executive function and hoarding in adults with obsessive-compulsive disorder Samuels, J; Bienvenu, OJ; Krasnow, J et al. Compr Psychiatry, DOI://10.1016/j.comppsych.2017.11.009 (2018)
Sequence determinants of protein phase behavior from a coarse-grained model Dignon, GL; Zheng, W; Kim, YC; Best, RB; Mittal, J; PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1005941 (2018)
Genomic Heterogeneity Within Individual Prostate Cancer Foci Impacts Predictive Biomarkers of Targeted Therapy VanderWeele, DJ; Finney, R; Katayama, K et al. Eur Urol Focus, DOI://10.1016/j.euf.2018.01.006 (2018)
Extended amygdala connectivity changes during sustained shock anticipation Torrisi, S; Gorka, AX; Gonzalez-Castillo, J et al. Transl Psychiatry, DOI://10.1038/s41398-017-0074-6 (2018)
Unraveling the molecular mechanism of interactions of the Rho GTPases Cdc42 and Rac1 with the scaffolding protein IQGAP2 Ozdemir, ES; Jang, H; Gursoy, A et al. J. Biol. Chem., DOI://10.1074/jbc.RA117.001596 (2018)
Binding kinetics of ultrasmall gold nanoparticles with proteins André Lira, Rodrigo Ferreira, Ricardo Torquato, Huaying Zhao, Maria Luiza Oliva, Sergio A. Hassan, Peter Schuck and Alioscka A Sousa Nanoscale, DOI: 10.1039/C7NR06810G (2018)

Cleavage of TL1A Differentially Regulates Its Effects on Innate and Adaptive Immune Cells Ferdinand, JR; Richard, AC; Meylan, F; Al-Shamkhani, A; Siegel, RM; J. Immunol., DOI://10.4049/jimmunol.1700891 (2018)
De novo assembly of the complex genome of Nippostrongylus brasiliensis using MinION long reads Eccles, D; Chandler, J; Camberis, M et al. BMC Biol., DOI://10.1186/s12915-017-0473-4 (2018)
Accelerometer-Measured Physical Activity and Sedentary Behavior in Relation to All-Cause Mortality: The Women's Health Study Lee, IM; Shiroma, EJ; Evenson, KR; Kamada, M; LaCroix, AZ; Buring, JE; Circulation, DOI://10.1161/CIRCULATIONAHA.117.031300 (2018)
Altered avalanche dynamics in a developmental NMDAR hypofunction model of cognitive impairment Seshadri, S; Klaus, A; Winkowski, DE; Kanold, PO; Plenz, D; Transl Psychiatry, DOI://10.1038/s41398-017-0060-z (2018)
Single-cell analysis reveals cancer stem cell heterogeneity in hepatocellular carcinoma Zheng, H; Pomyen, Y; Hernandez, MO et al. Hepatology, DOI://10.1002/hep.29778 (2018)
Effects of HLA-B27 on Gut Microbiota in Experimental Spondyloarthritis Implicate an Ecological Model of Dysbiosis Gill, T; Asquith, M; Brooks, SR; Rosenbaum, JT; Colbert, RA; Arthritis Rheumatol., DOI://10.1002/art.40405 (2018)

2017 (409 papers)

Flexible risk prediction models for left or interval-censored data from electronic health records Hyun, N; Cheung, LC; Pan, Q; Schiffman, M; Katki, HA; , Ann Appl Stat, DOI://10.1214/17-AOAS1036 (2017)
Phantoms models to characterize influenza hemagglutinin-based vaccines McCraw, DM; Harris, AK; , Microsc. Microanal., DOI://10.1017/S1431927617007279 (2017)
Inhibitors of the Histone Methyltransferases EZH2/1 Induce a Potent Antiviral State and Suppress Infection by Diverse Viral Pathogens Arbuckle, JH; Gardina, PJ; Gordon, DN et al. mBio, DOI://10.1128/mBio.01141-17 (2017)
Social influence on 5-year survival in a longitudinal chemotherapy ward co-presence network Lienert, J; Marcum, CS; Finney, J; Reed-Tsochas, F; Koehly, L; , Netw Sci (Camb Univ Press), DOI://10.1017/nws.2017.16 (2017)
SpotLearn: Convolutional Neural Network for Detection of Fluorescence In Situ Hybridization (FISH) Signals in High-Throughput Imaging Approaches Gudla, PR; Nakayama, K; Pegoraro, G; Misteli, T; Cold Spring Harb. Symp. Quant. Biol., DOI://10.1101/sqb.2017.82.033761 (2017)
Structural variants in genes associated with human Williams-Beuren syndrome underlie stereotypical hypersociability in domestic dogs vonHoldt, BM; Shuldiner, E; Koch, IJ et al. Sci Adv, DOI://10.1126/sciadv.1700398 (2017)
Structural deficits in salience network regions are associated with increased impulsivity and compulsivity in alcohol dependence Grodin, EN; Cortes, CR; Spagnolo, PA; Momenan, R; , Drug Alcohol Depend, DOI://10.1016/j.drugalcdep.2017.06.014 (2017)
Regulation of chromatin folding by conformational variations of nucleosome linker DNA Buckwalter, JM; Norouzi, D; Harutyunyan, A; Zhurkin, VB; Grigoryev, SA; , Nucleic Acids Res., DOI://10.1093/nar/gkx562 (2017)
La Deletion from Mouse Brain Alters Pre-tRNA Metabolism and Accumulation of Pre-5.8S rRNA, with Neuron Death and Reactive Astrocytosis Blewett, NH; Iben, JR; Gaidamakov, S; Maraia, RJ; , Mol. Cell. Biol., DOI://10.1128/MCB.00588-16 (2017)
Effects of spatial fMRI resolution on the classification of naturalistic movies Mandelkow, H; de Zwart, JA; Duyn, JH; Neuroimage, DOI://10.1016/j.neuroimage.2017.08.053 (2017)
Extracellular vesicles, exosomes and shedding vesicles in regenerative medicine - a new paradigm for tissue repair Bjørge, IM; Kim, SY; Mano, JF; Kalionis, B; Chrzanowski, W; Biomater Sci, DOI://10.1039/c7bm00479f (2017)
Automatic magnetic resonance prostate segmentation by deep learning with holistically nested networks Cheng, R; Roth, HR; Lay, N et al. J Med Imaging (Bellingham), DOI://10.1117/1.JMI.4.4.041302 (2017)
The emerging importance and challenges of the human mycobiome Kong, HH; Morris, A; Virulence, DOI://10.1080/21505594.2017.1279780 (2017)
Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells Lin, JX; Du, N; Li, P et al. Nat Commun, DOI://10.1038/s41467-017-01477-5 (2017)
BRD4 facilitates DNA damage response and represses CBX5/Heterochromatin protein 1 (HP1) Pongas, G; Kim, MK; Min, DJ et al. Oncotarget, DOI://10.18632/oncotarget.17572 (2017)
Bitopic fluorescent antagonists of the A2A adenosine receptor based on pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine functionalized congeners Duroux, R; Ciancetta, A; Mannes, P et al. Medchemcomm, DOI://10.1039/C7MD00247E (2017)
Haploinsufficiency of ZNF462 is associated with craniofacial anomalies, corpus callosum dysgenesis, ptosis, and developmental delay Weiss, K; Wigby, K; Fannemel, M et al. Eur. J. Hum. Genet., DOI://10.1038/ejhg.2017.86 (2017)
Longitudinal Structural and Functional Differences Between Proportional and Poor Motor Recovery After Stroke Guggisberg, AG; Nicolo, P; Cohen, LG; Schnider, A; Buch, ER; Neurorehabil Neural Repair, DOI://10.1177/1545968317740634 (2017)

STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes: Functional dissection of the Il2ra gene locus Li, P; Mitra, S; Spolski, R et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1714019114 (2017)
Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis van Rooij, FJA; Qayyum, R; Smith, AV et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2016.11.016 (2017)
Comparative Transcriptome Profiling Reveals Coding and Noncoding RNA Differences in NSCLC from African Americans and European Americans Mitchell, KA; Zingone, A; Toulabi, L; Boeckelman, J; Ryan, BM; , Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-17-0527 (2017)
Testis-specific transcriptional regulators selectively occupy BORIS-bound CTCF target regions in mouse male germ cells Rivero-Hinojosa, S; Kang, S; Lobanenkov, VV; Zentner, GE; Sci Rep, DOI://10.1038/srep41279 (2017)
Preparation of a Conditional RNA Switch Zakrevsky, P; Parlea, L; Viard, M; Bindewald, E; Afonin, KA; Shapiro, BA; , Methods Mol. Biol., DOI://10.1007/978-1-4939-7138-1_20 (2017)
Computational Generation of RNA Nanorings Sharan, R; Bindewald, E; Kasprzak, WK; Shapiro, BA; , Methods Mol. Biol., DOI://10.1007/978-1-4939-7138-1_2 (2017)
Protocols for Molecular Dynamics Simulations of RNA Nanostructures Kim, T; Kasprzak, WK; Shapiro, BA; , Methods Mol. Biol., DOI://10.1007/978-1-4939-7138-1_3 (2017)
Common Molecular Subtypes Among Asian Hepatocellular Carcinoma and Cholangiocarcinoma Chaisaingmongkol, J; Budhu, A; Dang, H et al. Cancer Cell, DOI://10.1016/j.ccell.2017.05.009 (2017)
Visualizing abnormalities in chest radiographs through salient network activations in Deep Learning Rajaraman S, Antani SK, Xue Z, Candemir S, Jaeger S, Thoma GR Proc. IEEE Life Sciences Conference (LSC), Sydney, Australia, 10.1109/LSC.2017.826814 (2017)
PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability Gryder, BE; Yohe, ME; Chou, HC et al. Cancer Discov, DOI://10.1158/2159-8290.CD-16-1297 (2017)
Parental bonding and hoarding in obsessive-compulsive disorder Chen, D; Bienvenu, OJ; Krasnow, J et al. Compr Psychiatry, DOI://10.1016/j.comppsych.2016.11.004 (2017)
Characterization of an Immunogenic Mutation in a Patient with Metastatic Triple-Negative Breast Cancer Assadipour, Y; Zacharakis, N; Crystal, JS et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-16-1423 (2017)
Systems-level identification of PKA-dependent signaling in epithelial cells Isobe, K; Jung, HJ; Yang, CR et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1709123114 (2017)
Association of red cell distribution width with all-cause and cardiovascular-specific mortality in African American and white adults: a prospective cohort study Tajuddin, SM; Nalls, MA; Zonderman, AB; Evans, MK; J Transl Med, DOI://10.1186/s12967-017-1313-6 (2017)
Sieve analysis using the number of infecting pathogens Follmann, D; Huang, CY; Biometrics, DOI://10.1111/biom.12833 (2017)
Meat Consumption During Pregnancy and Substance Misuse Among Adolescent Offspring: Stratification of TCN2 Genetic Variants Hibbeln, JR; SanGiovanni, JP; Golding, J et al. Alcohol. Clin. Exp. Res., DOI://10.1111/acer.13494 (2017)
A Systems Biology Approach to Investigating Sex Differences in Cardiac Hypertrophy Harrington, J; Fillmore, N; Gao, S et al. J Am Heart Assoc, DOI://10.1161/JAHA.117.005838 (2017)
Applying rigor and reproducibility standards to assay donor-derived cell-free DNA as a non-invasive method for detection of acute rejection and graft injury after heart transplantation Agbor-Enoh, S; Tunc, I; De Vlaminck, I et al. J. Heart Lung Transplant., DOI://10.1016/j.healun.2017.05.026 (2017)

Broadly protective murine monoclonal antibodies against influenza B virus target highly conserved neuraminidase epitopes Wohlbold, TJ; Podolsky, KA; Chromikova, V et al. Nat Microbiol, DOI://10.1038/s41564-017-0011-8 (2017)
Genome-wide association meta-analysis of fish and EPA+DHA consumption in 17 US and European cohorts Mozaffarian, D; Dashti, HS; Wojczynski, MK et al. PLoS ONE, DOI://10.1371/journal.pone.0186456 (2017)
Amygdala Contributions to Stimulus-Reward Encoding in the Macaque Medial and Orbital Frontal Cortex during Learning Rudebeck, PH; Ripple, JA; Mitz, AR; Averbeck, BB; Murray, EA; J. Neurosci., DOI://10.1523/JNEUROSCI.0933-16.2017 (2017)
Genome-wide identification of histone H2A and histone variant H2A.Z-interacting proteins by bPPI-seq Zhang, Y; Ku, WL; Liu, S et al. Cell Res., DOI://10.1038/cr.2017.112 (2017)
Deciphering the olfactory repertoire of the tiger mosquito Aedes albopictus Lombardo, F; Salvemini, M; Fiorillo, C et al. BMC Genomics, DOI://10.1186/s12864-017-4144-1 (2017)
Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS Taskesen, E; Mishra, A; van der Sluis, S et al. Sci Rep, DOI://10.1038/s41598-017-09320-z (2017)

Shelterin components mediate genome reorganization in response to replication stress Mizuguchi, T; Taneja, N; Matsuda, E et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1705527114 (2017)
The Interplay between Long- and Short-Range Temporal Correlations Shapes Cortex Dynamics across Vigilance States Meisel, C; Klaus, A; Vyazovskiy, VV; Plenz, D; J. Neurosci., DOI://10.1523/JNEUROSCI.0448-17.2017 (2017)
Insights Into Onchocerca volvulus Population Biology Through Multilocus Immunophenotyping Norice-Tra, CT; Ribeiro, J; Bennuru, S et al. J. Infect. Dis., DOI://10.1093/infdis/jix394 (2017)
Dynamic landscape of alternative polyadenylation during retinal development Hu, W; Li, S; Park, JY et al. Cell. Mol. Life Sci., DOI://10.1007/s00018-016-2429-1 (2017)
An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype Direk, N; Williams, S; Smith, JA et al. Biol. Psychiatry, DOI://10.1016/j.biopsych.2016.11.013 (2017)
The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins Wang, AH; Juan, AH; Ko, KD et al. Mol. Cell, DOI://10.1016/j.molcel.2017.09.016 (2017)

Untimely expression of gametogenic genes in vegetative cells causes uniparental disomy Folco, HD; Chalamcharla, VR; Sugiyama, T et al. Nature, DOI://10.1038/nature21372 (2017)
Pyrimidine Nucleotides Containing a (S)-Methanocarba Ring as P2Y6 Receptor Agonists Toti, KS; Jain, S; Ciancetta, A et al. Medchemcomm, DOI://10.1039/C7MD00397H (2017)
NFκB Promotes Ovarian Tumorigenesis via Classical Pathways That Support Proliferative Cancer Cells and Alternative Pathways That Support ALDH+ Cancer Stem-like Cells House, CD; Jordan, E; Hernandez, L et al. Cancer Res., DOI://10.1158/0008-5472.CAN-17-0366 (2017)
ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer Shukla, V; Rao, M; Zhang, H et al. Cancer Res., DOI://10.1158/0008-5472.CAN-17-0570 (2017)
SNF2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance and Proper Replication Taneja, N; Zofall, M; Balachandran, V et al. Mol. Cell, DOI://10.1016/j.molcel.2017.02.006 (2017)
High-Resolution CBV-fMRI Allows Mapping of Laminar Activity and Connectivity of Cortical Input and Output in Human M1 Huber, L; Handwerker, DA; Jangraw, DC et al. Neuron, DOI://10.1016/j.neuron.2017.11.005 (2017)

KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis Murgai, M; Ju, W; Eason, M et al. Nat. Med., DOI://10.1038/nm.4400 (2017)
CTCF-Mediated Enhancer-Promoter Interaction Is a Critical Regulator of Cell-to-Cell Variation of Gene Expression Ren, G; Jin, W; Cui, K et al. Mol. Cell, DOI://10.1016/j.molcel.2017.08.026 (2017)
Bromodomain and Extraterminal Protein Inhibitor JQ1 Suppresses Thyroid Tumor Growth in a Mouse Model Zhu, X; Enomoto, K; Zhao, L et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-16-0914 (2017)
Molecular-based diagnosis of multiple sclerosis and its progressive stage Barbour, C; Kosa, P; Komori, M et al. Ann. Neurol., DOI://10.1002/ana.25083 (2017)
Serum starvation of ARPE-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration Rajapakse, D; Peterson, K; Mishra, S; Wistow, G; Exp. Cell Res., DOI://10.1016/j.yexcr.2017.10.036 (2017)
Crystal Structures of Diaryliodonium Fluorides and Their Implications for Fluorination Mechanisms Lee, YS; Chun, JH; Hodošček, M; Pike, VW; Chemistry, DOI://10.1002/chem.201604803 (2017)

Loci associated with skin pigmentation identified in African populations Crawford, NG; Kelly, DE; Hansen, MEB et al. Science, DOI://10.1126/science.aan8433 (2017)
eIF1A residues implicated in cancer stabilize translation preinitiation complexes and favor suboptimal initiation sites in yeast Martin-Marcos, P; Zhou, F; Karunasiri, C et al. Elife, DOI://10.7554/eLife.31250 (2017)
Polygenic risk score and heritability estimates reveals a genetic relationship between ASD and OCD Guo, W; Samuels, JF; Wang, Y et al. Eur Neuropsychopharmacol, DOI://10.1016/j.euroneuro.2017.03.011 (2017)
Molecular basis of CENP-C association with the CENP-A nucleosome at yeast centromeres Xiao, H; Wang, F; Wisniewski, J et al. Genes Dev., DOI://10.1101/gad.304782.117 (2017)
T-Cell Transfer Therapy Targeting Mutant KRAS Rosenberg, SA; Tran, E; Robbins, PF; N. Engl. J. Med., DOI://10.1056/NEJMc1616637 (2017)
Correction: The complex genetics of gait speed: genome-wide meta-analysis approach Ben-Avraham, D; Karasik, D; Verghese, J et al. Aging (Albany NY), DOI://10.18632/aging.101260 (2017)

Effect of Threat on Right dlPFC Activity during Behavioral Pattern Separation Balderston, NL; Hsiung, A; Ernst, M; Grillon, C; J. Neurosci., DOI://10.1523/JNEUROSCI.0717-17.2017 (2017)
GATE: an efficient procedure in study of pleiotropic genetic associations Zhang, W; Yang, L; Tang, LL et al. BMC Genomics, DOI://10.1186/s12864-017-3928-7 (2017)
Progressive and Multi-path Holistically Nested Neural Networks for Pathological Lung Segmentation from CT Images Harrison A.P., Xu Z., George K., Lu L., Summers R.M., Mollura D.J. In: Descoteaux M., Maier-Hein L., Franz A., Jannin P., Colli, 10.1007/978-3-319-66179-7-71 (2017)
Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease Warren, CR; O'Sullivan, JF; Friesen, M et al. Cell Stem Cell, DOI://10.1016/j.stem.2017.01.010 (2017)
An Adult Mouse Thyroid Side Population Cell Line that Exhibits Enriched Epithelial-Mesenchymal Transition Murata, T; Iwadate, M; Takizawa, Y et al. Thyroid, DOI://10.1089/thy.2016.0130 (2017)
NRF1 coordinates with DNA methylation to regulate spermatogenesis Wang, J; Tang, C; Wang, Q et al. FASEB J., DOI://10.1096/fj.201700093R (2017)

Two Distinct Actin Networks Mediate Traction Oscillations to Confer Focal Adhesion Mechanosensing Wu, Z; Plotnikov, SV; Moalim, AY; Waterman, CM; Liu, J; Biophys. J., DOI://10.1016/j.bpj.2016.12.035 (2017)
'Final common pathway' of human cancer immunotherapy: targeting random somatic mutations Tran, E; Robbins, PF; Rosenberg, SA; Nat. Immunol., DOI://10.1038/ni.3682 (2017)
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 Expression Parkhurst, M; Gros, A; Pasetto, A et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-16-2680 (2017)
The Distinct Transcriptional Response of the Midgut of Amblyomma sculptum and Amblyomma aureolatum Ticks to Rickettsia rickettsii Correlates to Their Differences in Susceptibility to Infection Martins, LA; Galletti, MFBM; Ribeiro, JM et al. Front Cell Infect Microbiol, DOI://10.3389/fcimb.2017.00129 (2017)
Defining Disease, Diagnosis, and Translational Medicine within a Homeostatic Perturbation Paradigm: The National Institutes of Health Undiagnosed Diseases Program Experience Gall, T; Valkanas, E; Bello, C et al. Front Med (Lausanne), DOI://10.3389/fmed.2017.00062 (2017)
Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations Hu, Y; Tanaka, T; Zhu, J et al. J. Lipid Res., DOI://10.1194/jlr.P071860 (2017)
Binding of protofibrillar Aβ trimers to lipid bilayer surface enhances Aβ structural stability and causes membrane thinning Dong, X; Sun, Y; Wei, G; Nussinov, R; Ma, B; Phys Chem Chem Phys, DOI://10.1039/c7cp05959k (2017)
Temporal similarity perfusion mapping: A standardized and model-free method for detecting perfusion deficits in stroke Song, S; Bokkers, RPH; Luby, M et al. PLoS ONE, DOI://10.1371/journal.pone.0185552 (2017)
Genome Wide Association Study (GWAS) between Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD) Ritter, ML; Guo, W; Samuels, JF et al. Front Mol Neurosci, DOI://10.3389/fnmol.2017.00083 (2017)
Extending electrostatics of dielectric spheres to arbitrary charge distributions with applications to biosystems T. P. Doerr, O. I. Obolensky, and Yi-Kuo Yu Phys. Rev. E , doi://10.1103/PhysRevE.96.062414 (2017)
The full transcription map of mouse papillomavirus type 1 (MmuPV1) in mouse wart tissues Xue, XY; Majerciak, V; Uberoi, A et al. PLoS Pathog., DOI://10.1371/journal.ppat.1006715 (2017)
Reduced Local and Increased Long-Range Functional Connectivity of the Thalamus in Autism Spectrum Disorder Tomasi, D; Volkow, ND; Cereb. Cortex, DOI://10.1093/cercor/bhx340 (2017)

Highly Efficient Cpf1-Mediated Gene Targeting in Mice Following High Concentration Pronuclear Injection Watkins-Chow, DE; Varshney, GK; Garrett, LJ et al. G3 (Bethesda), DOI://10.1534/g3.116.038091 (2017)
CDC14A Phosphatase is Essential for Hearing and Male Fertility in Mouse and Human Imtiaz, A; Belyantseva, IA; Beirl, AJ et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddx440 (2017)
Identifying subgroups of enhanced predictive accuracy from longitudinal biomarker data using tree-based approaches: applications to fetal growth Foster, JC; Liu, D; Albert, PS; Liu, A; J R Stat Soc Ser A Stat Soc, DOI://10.1111/rssa.12182 (2017)
Generation and characterization of Kctd15 mutations in zebrafish Heffer, A; Marquart, GD; Aquilina-Beck, A; Saleem, N; Burgess, HA; Dawid, IB; PLoS ONE, DOI://10.1371/journal.pone.0189162 (2017)
Prediction of nearest neighbor effects on backbone torsion angles and NMR scalar coupling constants in disordered proteins Shen, Y; Roche, J; Grishaev, A; Bax, A; Protein Sci., DOI://10.1002/pro.3292 (2017)
Selection for long and short sleep duration in Drosophila melanogaster reveals the complex genetic network underlying natural variation in sleep Harbison, ST; Serrano Negron, YL; Hansen, NF; Lobell, AS; PLoS Genet., DOI://10.1371/journal.pgen.1007098 (2017)

Structural mechanisms of centromeric nucleosome recognition by the kinetochore protein CENP-N Chittori, S; Hong, J; Saunders, H et al. Science, DOI://10.1126/science.aar2781 (2017)
Identity-by-Descent Mapping Identifies Major Locus for Serum Triglycerides in Amerindians Largely Explained by an APOC3 Founder Mutation Hsueh, WC; Nair, AK; Kobes, S et al. Circ Cardiovasc Genet, DOI://10.1161/CIRCGENETICS.117.001809 (2017)
Detecting treatment differences in group sequential longitudinal studies with covariate adjustment Jeffries, NO; Troendle, JF; Geller, NL; Biometrics, DOI://10.1111/biom.12837 (2017)
Comparison of Additive and Polarizable Models with Explicit Treatment of Long-Range Lennard-Jones Interactions using Alkane Simulations Leonard, AN; Simmonett, AC; Pickard, FC et al. J Chem Theory Comput, DOI://10.1021/acs.jctc.7b00948 (2017)
Structural basis for nucleotide-modulated p97 association with the ER membrane Tang, WK; Zhang, T; Ye, Y; Xia, D; Cell Discov, DOI://10.1038/celldisc.2017.45 (2017)
Structural host-microbiota interaction networks Guven-Maiorov, E; Tsai, CJ; Nussinov, R; PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1005579 (2017)
Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq Chen, L; Lee, JW; Chou, CL et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1710964114 (2017)
Exploring Effects of Sex and Diet on Drosophila melanogaster Head Gene Expression Jaime, MDLA; Hurtado, J; Loustalot-Laclette, MR; Oliver, B; Markow, T; J Genomics, DOI://10.7150/jgen.22393 (2017)
The emergence and evolution of influenza A (H1α) viruses in swine in Canada and the United States Nelson, MI; Culhane, MR; Trovão, NS et al. J. Gen. Virol., DOI://10.1099/jgv.0.000924 (2017)
New Multiple Sclerosis Disease Severity Scale Predicts Future Accumulation of Disability Weideman, AM; Barbour, C; Tapia-Maltos, MA et al. Front Neurol, DOI://10.3389/fneur.2017.00598 (2017)
CRISPR/Cas9-mediated gene knockout is insensitive to target copy number but is dependent on guide RNA potency and Cas9/sgRNA threshold expression level Yuen, G; Khan, FJ; Gao, S et al. Nucleic Acids Res., DOI://10.1093/nar/gkx843 (2017)
Graph theory reveals amygdala modules consistent with its anatomical subdivisions Caparelli, EC; Ross, TJ; Gu, H; Liang, X; Stein, EA; Yang, Y; Sci Rep, DOI://10.1038/s41598-017-14613-4 (2017)
Molecular Anatomy of the Developing Human Retina Hoshino, A; Ratnapriya, R; Brooks, MJ et al. Dev. Cell, DOI://10.1016/j.devcel.2017.10.029 (2017)
Arginine Kinases from the Precious Corals Corallium rubrum and Paracorallium japonicum: Presence of Two Distinct Arginine Kinase Gene Lineages in Cnidarians Matsuo, T; Yano, D; Uda, K; Iwasaki, N; Suzuki, T; Protein J., DOI://10.1007/s10930-017-9745-7 (2017)
Lasting deficit in inhibitory control with mild traumatic brain injury Xu, B; Sandrini, M; Levy, S et al. Sci Rep, DOI://10.1038/s41598-017-14867-y (2017)
Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions Kim, J; Sturgill, D; Sebastian, R et al. Mol. Cell, DOI://10.1016/j.molcel.2017.11.021 (2017)
Dosage-Dependent Expression Variation Suppressed on the Drosophila Male X Chromosome Lee, H; Cho, DY; Wojtowicz, D et al. G3 (Bethesda), DOI://10.1534/g3.117.300400 (2017)
Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance Rosshart, SP; Vassallo, BG; Angeletti, D et al. Cell, DOI://10.1016/j.cell.2017.09.016 (2017)
Dynamic regulation of lysine acetylation: the balance between acetyltransferase and deacetylase activities Hyndman, KA; Knepper, MA; Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00313.2017 (2017)
Integrative Genomic Analysis of Coincident Cancer Foci Implicates CTNNB1 and PTEN Alterations in Ductal Prostate Cancer Gillard, M; Lack, J; Pontier, A et al. Eur Urol Focus, DOI://10.1016/j.euf.2017.12.003 (2017)
Holistic segmentation of the lung in cine MRI Kovacs, W; Hsieh, N; Roth, H et al. J Med Imaging (Bellingham), DOI://10.1117/1.JMI.4.4.041310 (2017)
Identification of essential genes for cancer immunotherapy Patel, SJ; Sanjana, NE; Kishton, RJ et al. Nature, DOI://10.1038/nature23477 (2017)
Transcriptomic profiling of the human brain reveals that altered synaptic gene expression is associated with chronological aging Dillman, AA; Majounie, E; Ding, J et al. Sci Rep, DOI://10.1038/s41598-017-17322-0 (2017)
In vivo tropism of Salmonella Typhi toxin to cells expressing a multiantennal glycan receptor Yang, YA; Lee, S; Zhao, J et al. Nat Microbiol, DOI://10.1038/s41564-017-0076-4 (2017)

Local and global anatomy of antibody-protein antigen recognition Wang, M; Zhu, D; Zhu, J; Nussinov, R; Ma, B; J. Mol. Recognit., DOI://10.1002/jmr.2693 (2017)
A digital 3D atlas of the marmoset brain based on multi-modal MRI Liu, C; Ye, FQ; Chern-Chyi Yen, C et al. Neuroimage, DOI://10.1016/j.neuroimage.2017.12.004 (2017)
Automated quality assessment of structural magnetic resonance images in children: Comparison with visual inspection and surface-based reconstruction White, T; Jansen, PR; Muetzel, RL et al. Hum Brain Mapp, DOI://10.1002/hbm.23911 (2017)
Power Analysis for Genetic Association Test (PAGEANT) provides insights to challenges for rare variant association studies Derkach, A; Zhang, H; Chatterjee, N; Bioinformatics, DOI://10.1093/bioinformatics/btx770 (2017)
OCT4 supports extended LIF-independent self-renewal and maintenance of transcriptional and epigenetic networks in embryonic stem cells He, R; Xhabija, B; Al-Qanber, B; Kidder, BL; Sci Rep, DOI://10.1038/s41598-017-16611-y (2017)
Demystifying P2Y1 Receptor Ligand Recognition through Docking and Molecular Dynamics Analyses Ciancetta, A; O'Connor, RD; Paoletta, S; Jacobson, KA; J Chem Inf Model, DOI://10.1021/acs.jcim.7b00528 (2017)
Landscape of immunogenic tumor antigens in successful immunotherapy of virally induced epithelial cancer Stevanović, S; Pasetto, A; Helman, SR et al. Science, DOI://10.1126/science.aak9510 (2017)
HiHiMap: single-cell quantitation of histones and histone posttranslational modifications across the cell cycle by high-throughput imaging Zane, L; Chapus, F; Pegoraro, G; Misteli, T; Mol. Biol. Cell, DOI://10.1091/mbc.E16-12-0870 (2017)
A STAT3-dependent transcriptional circuitry inhibits cytotoxic gene expression in T cells Ciucci, T; Vacchio, MS; Bosselut, R; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1711160114 (2017)
Natural Language Processing for Large-Scale Medical Image Analysis Using Deep Learning Hoo-Chang Shin, Le Lu, Ronald M. Summers in Deep Learning for Medical Image Analysis, Elsevier , (p405-421) (2017)
Allometric Analysis Detects Brain Size-Independent Effects of Sex and Sex Chromosome Complement on Human Cerebellar Organization Mankiw, C; Park, MTM; Reardon, PK et al. J. Neurosci., DOI://10.1523/JNEUROSCI.2158-16.2017 (2017)
Excessive burden of lysosomal storage disorder gene variants in Parkinson's disease Robak, LA; Jansen, IE; van Rooij, J et al. Brain, DOI://10.1093/brain/awx285 (2017)

Insights into functions of the H channel of cytochrome c oxidase from atomistic molecular dynamics simulations Sharma, V; Jambrina, PG; Kaukonen, M; Rosta, E; Rich, PR; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1708628114 (2017)
Conventional and pioneer modes of glucocorticoid receptor interaction with enhancer chromatin in vivo Johnson, TA; Chereji, RV; Stavreva, DA; Morris, SA; Hager, GL; Clark, DJ; Nucleic Acids Res., DOI://10.1093/nar/gkx1044 (2017)
A joint model for multivariate hierarchical semicontinuous data with replications Kassahun-Yimer, W; Albert, PS; Lipsky, LM; Nansel, TR; Liu, A; Stat Methods Med Res, DOI://10.1177/0962280217738141 (2017)
Phosphorylated Calmodulin Promotes PI3K Activation by Binding to the SH2 Domains Zhang, M; Jang, H; Gaponenko, V; Nussinov, R; Biophys. J., DOI://10.1016/j.bpj.2017.09.008 (2017)
Physiological and pathophysiological implications of PGE2 and the PGE2 synthases in the kidney Wang, J; Liu, M; Zhang, X; Yang, G; Chen, L; Prostaglandins Other Lipid Mediat., DOI://10.1016/j.prostaglandins.2017.10.006 (2017)
Prediction of Host-Pathogen Interactions for Helicobacter pylori by Interface Mimicry and Implications to Gastric Cancer Guven-Maiorov, E; Tsai, CJ; Ma, B; Nussinov, R; J. Mol. Biol., DOI://10.1016/j.jmb.2017.10.023 (2017)

Independence between pre-mRNA splicing and DNA methylation in an isogenic minigene resource Kyster K. Nanan, Cody Ocheltree, David Sturgill, Mariana D. Mandler, Maria Prigge, Garima Varma, Shalini Oberdoerffer Nucleic Acids Res., doi://10.1093/nar/gkx900 (2017)
Analysis of Gap Times Based on Panel Count Data With Informative Observation Times and Unknown Start Time Ling Ma and Rajeshwari Sundaram J. Am. Stat. Assoc, doi://10.1080/01621459.2016.1246369 (2017)
Multimodal mapping of the brain's functional connectivity and the adult outcome of attention deficit hyperactivity disorder Sudre, G; Szekely, E; Sharp, W; Kasparek, S; Shaw, P; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1705229114 (2017)
The Kölliker-Fuse nucleus orchestrates the timing of expiratory abdominal nerve bursting Barnett, WH; Jenkin, SEM; Milsom, WK et al. J. Neurophysiol., DOI://10.1152/jn.00499.2017 (2017)
PaRSnIP: Sequence-Based Protein Solubility Prediction using Gradient Boosting Machine Rawi, R; Mall, R; Kunji, K; Shen, CH; Kwong, PD; Chuang, GY; Bioinformatics, DOI://10.1093/bioinformatics/btx662 (2017)
Subset- and tissue-defined STAT5 thresholds control homeostasis and function of innate lymphoid cells Villarino, AV; Sciumè, G; Davis, FP et al. J. Exp. Med., DOI://10.1084/jem.20150907 (2017)

Unpicking the determinants of amide NHO[double bond, length as m-dash]C hydrogen bond strength with diphenylacetylene molecular balances Luccarelli, J; Jones, IM; Thompson, S; Hamilton, AD; Org. Biomol. Chem., DOI://10.1039/c7ob02026k (2017)
Peptide dimerization-dissociation rates from replica exchange molecular dynamics Leahy, CT; Kells, A; Hummer, G; Buchete, NV; Rosta, E; J Chem Phys, DOI://10.1063/1.5004774 (2017)
Identification of UT-A1-and AQP2 interacting proteins in rat inner medullary collecting duct Chou, CL; Hwang, G; Hageman, DJ et al. Am. J. Physiol., Cell Physiol., DOI://10.1152/ajpcell.00082.2017 (2017)
Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex Guo, TW; Bartesaghi, A; Yang, H et al. Cell, DOI://10.1016/j.cell.2017.09.006 (2017)
How Many Protein Sequences Fold to a Given Structure? A Coevolutionary Analysis Tian, P; Best, RB; Biophys. J., DOI://10.1016/j.bpj.2017.08.039 (2017)
A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency Aoki, M; Hayashi, H; Rao, KV et al. Elife, DOI://10.7554/eLife.28020 (2017)
The FUT2 secretor variant p.Trp154Ter influences serum vitamin B12 concentration via holo-haptocorrin, but not holo-transcobalamin, and is associated with haptocorrin glycosylation Velkova, A; Diaz, JEL; Pangilinan, F et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddx369 (2017)
A functional connectivity-based neuromarker of sustained attention generalizes to predict recall in a reading task Jangraw, DC; Gonzalez-Castillo, J; Handwerker, DA et al. Neuroimage, DOI://10.1016/j.neuroimage.2017.10.019 (2017)
MELD: Mixed effects for large datasets Nielson, DM; Sederberg, PB; PLoS ONE, DOI://10.1371/journal.pone.0182797 (2017)
MicroRNA Signature of Cigarette Smoking and Evidence for a Putative Causal Role of MicroRNAs in Smoking-Related Inflammation and Target Organ Damage Willinger, CM; Rong, J; Tanriverdi, K et al. Circ Cardiovasc Genet, DOI://10.1161/CIRCGENETICS.116.001678 (2017)
De novo Assembly of a New Solanum pennellii Accession Using Nanopore Sequencing Schmidt, MH; Vogel, A; Denton, AK et al. Plant Cell, DOI://10.1105/tpc.17.00521 (2017)
Rapid Nanopore Sequencing of Plasmids and Resistance Gene Detection in Clinical Isolates Lemon, JK; Khil, PP; Frank, KM; Dekker, JP; J. Clin. Microbiol., DOI://10.1128/JCM.01069-17 (2017)

TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF Seberg, HE; Van Otterloo, E; Loftus, SK et al. PLoS Genet., DOI://10.1371/journal.pgen.1006636 (2017)
Molecular Dynamics Simulations of Ceramide and Ceramide-Phosphatidylcholine Bilayers Wang, E; Klauda, JB; J Phys Chem B, DOI://10.1021/acs.jpcb.7b08967 (2017)
CHD7 deficiency delays leukemogenesis in mice induced by CBFB-MYH11 Zhen, T; Kwon, E; Zhao, L et al. Blood, DOI://10.1182/blood-2017-04-780106 (2017)
Molecular architecture underlying fluid absorption by the developing inner ear Honda, K; Kim, SH; Kelly, MC et al. Elife, DOI://10.7554/eLife.26851 (2017)
Moderate blast exposure alters gene expression and levels of amyloid precursor protein Gill, J; Cashion, A; Osier, N et al. Neurol Genet, DOI://10.1212/NXG.0000000000000186 (2017)
Preclinical testing of the glycogen synthase kinase-3β inhibitor tideglusib for rhabdomyosarcoma Bharathy, N; Svalina, MN; Settelmeyer, TP et al. Oncotarget, DOI://10.18632/oncotarget.18520 (2017)

Novel near-diploid ovarian cancer cell line derived from a highly aneuploid metastatic ovarian tumor Rozenblum, E; Sotelo-Silveira, JR; Kim, GY et al. PLoS ONE, DOI://10.1371/journal.pone.0182610 (2017)
SMYD5 controls heterochromatin and chromosome integrity during embryonic stem cell differentiation Kidder, BL; He, R; Wangsa, D et al. Cancer Res., DOI://10.1158/0008-5472.CAN-17-0828 (2017)
GRL-09510, a Unique P2-Crown-Tetrahydrofuranylurethane -Containing HIV-1 Protease Inhibitor, Maintains Its Favorable Antiviral Activity against Highly-Drug-Resistant HIV-1 Variants in vitro Amano, M; Miguel Salcedo-Gómez, P; Yedidi, RS et al. Sci Rep, DOI://10.1038/s41598-017-12052-9 (2017)
Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains Murray, DT; Kato, M; Lin, Y et al. Cell, DOI://10.1016/j.cell.2017.08.048 (2017)
Piecewise Polynomial Approximations To The Icrp 116 Effective Dose Coefficients: Photons And Neutrons M. M. Mille N. E. Hertel P. M. Bergstrom C. Lee Radiation Protection Dosimetry, doi://10.1093/rpd/ncx112 (2017)
Estimating onset time from longitudinal and cross-sectional data with an application to estimating gestational age from longitudinal maternal anthropometry during pregnancy and neonatal anthropometry at birth Ana Maria Ortega-Villa, Katherine L. Grantz, Paul S. Albert J. Roy. Stat. Soc., DOI: 10.1111/rssa.12312 (2017)

Decline of long-range temporal correlations in the human brain during sustained wakefulness Meisel, C; Bailey, K; Achermann, P; Plenz, D; Sci Rep, DOI://10.1038/s41598-017-12140-w (2017)
Mechanisms of recognition of amyloid-β (Aβ) monomer, oligomer, and fibril by homologous antibodies Zhao, J; Nussinov, R; Ma, B; J. Biol. Chem., DOI://10.1074/jbc.M117.801514 (2017)
Topological structure determination of RNA using small angle X-ray scattering Bhandari, YR; Fan, L; Fang, X et al. J. Mol. Biol., DOI://10.1016/j.jmb.2017.09.006 (2017)
Nuclease activity gives an edge to host-defense peptide piscidin 3 over piscidin 1, rendering it more effective against persisters and biofilms Libardo, MDJ; Bahar, AA; Ma, B et al. FEBS J., DOI://10.1111/febs.14263 (2017)
Atropos: specific, sensitive, and speedy trimming of sequencing reads Didion, JP; Martin, M; Collins, FS; PeerJ, DOI://10.7717/peerj.3720 (2017)
Direct comparison of performance of single nucleotide variant calling in human genome with alignment-based and assembly-based approaches Wu, L; Yavas, G; Hong, H; Tong, W; Xiao, W; Sci Rep, DOI://10.1038/s41598-017-10826-9 (2017)

Paired Expression Analysis of Tumor Cell Surface Antigens Orentas, RJ; Sindiri, S; Duris, C et al. Front Oncol, DOI://10.3389/fonc.2017.00173 (2017)
Temporal interpolation alters motion in fMRI scans: Magnitudes and consequences for artifact detection Power, JD; Plitt, M; Kundu, P; Bandettini, PA; Martin, A; PLoS ONE, DOI://10.1371/journal.pone.0182939 (2017)
High-precision registration between zebrafish brain atlases using symmetric diffeomorphic normalization Marquart, GD; Tabor, KM; Horstick, EJ et al. Gigascience, DOI://10.1093/gigascience/gix056 (2017)
Global Inhibition with Specific Activation: How p53 and MYC Redistribute the Transcriptome in the DNA Double-Strand Break Response Porter, JR; Fisher, BE; Baranello, L et al. Mol. Cell, DOI://10.1016/j.molcel.2017.07.028 (2017)
Regulation of Noncoding Transcriptome in Developing Photoreceptors by Rod Differentiation Factor NRL Zelinger, L; Karakülah, G; Chaitankar, V et al. Invest. Ophthalmol. Vis. Sci., DOI://10.1167/iovs.17-21805 (2017)
Novel signal transducer and activator of transcription 1 mutation disrupts small ubiquitin-related modifier conjugation causing gain of function Sampaio, EP; Ding, L; Rose, SR et al. J. Allergy Clin. Immunol., DOI://10.1016/j.jaci.2017.07.027 (2017)

Higher-than-expected population prevalence of potentially pathogenic germline TP53 variants in individuals unselected for cancer history de Andrade, KC; Mirabello, L; Stewart, DR et al. Hum. Mutat., DOI://10.1002/humu.23320 (2017)
Statistical Methods for Standard Membrane-Feeding Assays to Measure Transmission Blocking or Reducing Activity in Malaria Bruce J. Swihart, Michael P. Fay & Kazutoyo Miura Journal of the American Statistical Association, doi://10.1080/01621459.2017.1356313 (2017)
The LDB1 Complex Co-opts CTCF for Erythroid Lineage-Specific Long-Range Enhancer Interactions Lee, J; Krivega, I; Dale, RK; Dean, A; Cell Rep, DOI://10.1016/j.celrep.2017.05.072 (2017)
MLL4 prepares the enhancer landscape for Foxp3 induction via chromatin looping Placek, K; Hu, G; Cui, K et al. Nat. Immunol., DOI://10.1038/ni.3812 (2017)
Therapeutic Antibodies to Ganglioside GD2 Evolved from Highly Selective Germline Antibodies Sterner, E; Peach, ML; Nicklaus, MC; Gildersleeve, JC; Cell Rep, DOI://10.1016/j.celrep.2017.07.050 (2017)
High-SETD8 inactivates p53 in neuroblastoma Veschi, V; Thiele, CJ; Oncoscience, DOI://10.18632/oncoscience.344 (2017)

Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation Kieffer-Kwon, KR; Nimura, K; Rao, SSP et al. Mol. Cell, DOI://10.1016/j.molcel.2017.07.013 (2017)
Anti-Inflammatory Chromatinscape Suggests Alternative Mechanisms of Glucocorticoid Receptor Action Oh, KS; Patel, H; Gottschalk, RA et al. Immunity, DOI://10.1016/j.immuni.2017.07.012 (2017)
Survival in adults and children with systemic lupus erythematosus: a systematic review and Bayesian meta-analysis of studies from 1950 to 2016 Tektonidou, MG; Lewandowski, LB; Hu, J; Dasgupta, A; Ward, MM; Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2017-211663 (2017)
Palmitoylation contributes to membrane curvature in Influenza A virus assembly and hemagglutinin-mediated membrane fusion Chlanda, P; Mekhedov, E; Waters, H et al. J. Virol., DOI://10.1128/JVI.00947-17 (2017)
Hydroxyl-radical footprinting combined with molecular modeling identifies unique features of DNA conformation and nucleosome positioning Alexey K. Shaytan, Hua Xiao, Grigoriy A. Armeev, Carl Wu, David Landsman, Anna R. Panchenko Nucleic Acids Res. , doi://10.1093/nar/gkx616 (2017)
Functional Subpopulations of Neurons in a Macaque Face Patch Revealed by Single-Unit fMRI Mapping Soo Hyun Park, Brian E. Russ, David B.T. McMahon, Kenji W. Koyano, Rebecca A. Berman, David A. Leopold Neuron, doi://10.1016/j.neuron.2017.07.014 (2017)

Stabilization of diastolic calcium signal via calcium pump regulation of complex local calcium releases and transient decay in a computational model of cardiac pacemaker cell with individual release channels Maltsev, AV; Maltsev, VA; Stern, MD; PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1005675 (2017)
Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity Monahan, Z; Ryan, VH; Janke, AM et al. EMBO J., DOI://10.15252/embj.201696394 (2017)
A very simple, re-executable neuroimaging publication Ghosh, SS; Poline, JB; Keator, DB et al. F1000Res, DOI://10.12688/f1000research.10783.2 (2017)
Katanin spiral and ring structures shed light on power stroke for microtubule severing Zehr, E; Szyk, A; Piszczek, G; Szczesna, E; Zuo, X; Roll-Mecak, A; Nat. Struct. Mol. Biol., DOI://10.1038/nsmb.3448 (2017)
Does accounting for seizure frequency variability increase clinical trial power Goldenholz, DM; Goldenholz, SR; Moss, R et al. Epilepsy Res., DOI://10.1016/j.eplepsyres.2017.07.013 (2017)
A Novel Method To Estimate Lymphocyte Dose And Application To Pediatric And Young Adult Ct Patients In The United Kingdom Choonsik Lee, Lindsay M. Morton, Amy Berrington de Gonzalez Radiation Dosimetry, doi://10.1093/rpd/ncx084 (2017)
Task-based dynamic functional connectivity: Recent findings and open questions Gonzalez-Castillo, J; Bandettini, PA; Neuroimage, DOI://10.1016/j.neuroimage.2017.08.006 (2017)
A common SLC26A4-linked haplotype underlying non-syndromic hearing loss with enlargement of the vestibular aqueduct Chattaraj, P; Munjal, T; Honda, K et al. J. Med. Genet., DOI://10.1136/jmedgenet-2017-104721 (2017)
Genetic background-dependent role of Egr1 for eyelid development Oh, J; Wang, Y; Chen, S et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1705848114 (2017)
A Two-Step Approach for Analysis of Nonignorable Missing Outcomes in Longitudinal Regression: an Application to Upstate KIDS Study Liu, D; Yeung, EH; McLain, AC; Xie, Y; Buck Louis, GM; Sundaram, R; Paediatr Perinat Epidemiol, DOI://10.1111/ppe.12382 (2017)
The prevalence of DICER1 pathogenic variation in population databases Kim, J; Field, A; Schultz, KAP; Hill, DA; Stewart, DR; Int. J. Cancer, DOI://10.1002/ijc.30907 (2017)
Systematic Investigation of Multi-TLR Sensing Identifies Regulators of Sustained Gene Activation in Macrophages Lin, B; Dutta, B; Fraser, IDC; Cell Syst, DOI://10.1016/j.cels.2017.06.014 (2017)

Combining Multiple Resting-State fMRI Features during Classification: Optimized Frameworks and Their Application to Nicotine Addiction Ding, X; Yang, Y; Stein, EA; Ross, TJ; Front Hum Neurosci, DOI://10.3389/fnhum.2017.00362 (2017)
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney Wain, LV; Vaez, A; Jansen, R et al. Hypertension, DOI://10.1161/HYPERTENSIONAHA.117.09438 (2017)
Neanderthal-Derived Genetic Variation Shapes Modern Human Cranium and Brain Gregory, MD; Kippenhan, JS; Eisenberg, DP et al. Sci Rep, DOI://10.1038/s41598-017-06587-0 (2017)
Genomic and metabolic characterization of a chromophobe renal cell carcinoma cell line model (UOK276) Yang, Y; Vocke, CD; Ricketts, CJ et al. Genes Chromosomes Cancer, DOI://10.1002/gcc.22476 (2017)
Genome Organization Drives Chromosome Fragility Canela, A; Maman, Y; Jung, S et al. Cell, DOI://10.1016/j.cell.2017.06.034 (2017)
A population-specific reference panel empowers genetic studies of Anabaptist populations Hou, L; Kember, RL; Roach, JC et al. Sci Rep, DOI://10.1038/s41598-017-05445-3 (2017)

Global alteration of the drug-binding pocket of human P-glycoprotein (ABCB1) by substitution of fifteen conserved residues reveals a negative correlation between substrate size and transport efficiency Vahedi, S; Chufan, EE; Ambudkar, SV; Biochem. Pharmacol., DOI://10.1016/j.bcp.2017.07.014 (2017)
Histone demethylases UTX and JMJD3 are required for NKT cell development in mice Northrup, D; Yagi, R; Cui, K et al. Cell Biosci, DOI://10.1186/s13578-017-0152-8 (2017)
Facultative CTCF sites moderate mammary super-enhancer activity and regulate juxtaposed gene in non-mammary cells Willi, M; Yoo, KH; Reinisch, F et al. Nat Commun, DOI://10.1038/ncomms16069 (2017)
How to control for unmeasured confounding in an observational time-to-event study with exposure incidence information: the treatment choice Cox model Troendle, J; Leifer, E; Zhang, Z; Yong, S; Tewes, H Stat. Med. , DOI: 10.1002/sim.7377 (2017)
Chromosome 3q22-29 amplification is linked to increased expression of multiple genes in key pathways deregulated in head and neck cancer tumors and cell lines Cheng H, Yang X, Si H et al. Cancer Research, DOI: 10.1158/1538-7445.AM2017-4374 (2017)
Deep Learning and Convolutional Neural Networks for Medical Image Computing: Precision Medicine, High Performance and Large-Scale Datasets edited by Le Lu, Yefeng Zheng, Gustavo Carneiro, Lin Yang Advances in Computer Vision and Pattern Recognition (2017)

Scaffolding of long read assemblies using long range contact information Ghurye, J; Pop, M; Koren, S; Bickhart, D; Chin, CS; BMC Genomics, DOI://10.1186/s12864-017-3879-z (2017)
Proper joint analysis of summary association statistics requires the adjustment of heterogeneity in SNP coverage pattern Han Zhang, William Wheeler, Lei Song, Kai Yu Briefings in Bioinformatics, doi://10.1093/bib/bbx072 (2017)
Oncogenic Activation of the RNA Binding Protein NELFE and MYC Signaling in Hepatocellular Carcinoma Dang, H; Takai, A; Forgues, M et al. Cancer Cell, DOI://10.1016/j.ccell.2017.06.002 (2017)
Longitudinal profiling reveals a persistent intestinal dysbiosis triggered by conventional anti-tuberculosis therapy Namasivayam, S; Maiga, M; Yuan, W et al. Microbiome, DOI://10.1186/s40168-017-0286-2 (2017)
Computer algorithms for automated detection and analysis of local Ca2+ releases in spontaneously beating cardiac pacemaker cells Maltsev, AV; Parsons, SP; Kim, MS et al. PLoS ONE, DOI://10.1371/journal.pone.0179419 (2017)
Staphylococcus aureus and Staphylococcus epidermidis strain diversity underlying pediatric atopic dermatitis Byrd, AL; Deming, C; Cassidy, SKB et al. Sci Transl Med, DOI://10.1126/scitranslmed.aal4651 (2017)

Genomic Analyses Reveal the Influence of Geographic Origin, Migration, and Hybridization on Modern Dog Breed Development Parker, HG; Dreger, DL; Rimbault, M et al. Cell Rep, DOI://10.1016/j.celrep.2017.03.079 (2017)
Clusters of calcium release channels harness the Ising phase transition to confine their elementary intracellular signals Maltsev, AV; Maltsev, VA; Stern, MD; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1701409114 (2017)
Pattern-mixture models with incomplete informative cluster size: application to a repeated pregnancy study Ashok Chaurasia, Danping Liu, Paul S. Albert Royal Statistical Society: Applied Statistics, DOI: 10.1111/rssc.12226 (2017)
Biopsy-guided learning with deep convolutional neural networks for Prostate Cancer detection on multiparametric MRI Tsehay Y, Lay N et al Biomedical Imaging, doi://10.1109/ISBI.2017.7950602 (2017)
Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers Steve TR, Li W-Q, Shi J, et al. Hum. Mol. Genet. , DOI: https://doi.org/10.1093/hmg/ddx188 (2017)
Type 2 diabetes, glucose, insulin, BMI, and ischemic stroke subtypes: Mendelian randomization study Larsson, SC; Scott, RA; Traylor, M et al. Neurology, DOI://10.1212/WNL.0000000000004173 (2017)

Whole-Genome Sequencing Overrules a Suspected Case of Carbapenem-Resistant Enterobacter cloacae Transmission Chen, M; Conlan, S; Lau, AF et al. J. Clin. Microbiol., DOI://10.1128/JCM.00915-17 (2017)
Defining the Neural Substrate of the Adult Outcome of Childhood ADHD: A Multimodal Neuroimaging Study of Response Inhibition Szekely, E; Sudre, GP; Sharp, W; Leibenluft, E; Shaw, P; Am J Psychiatry, DOI://10.1176/appi.ajp.2017.16111313 (2017)
Growth Inhibition of Colon Cancer and Melanoma Cells by Versiol Derivatives from a Paraconiothyrium Species Cho, N; Ransom, TT; Sigmund, J et al. J. Nat. Prod., DOI://10.1021/acs.jnatprod.7b00170 (2017)
De novo transcriptome assembly of loggerhead sea turtle nesting of the Colombian Caribbean Hernández-Fernández, J; Pinzón, A; Mariño-Ramírez, L; Genom Data, DOI://10.1016/j.gdata.2017.06.005 (2017)
Conserved and species-specific molecular denominators in mammalian skeletal muscle aging Mercken, EM; Capri, M; Carboneau, BA et al. NPJ Aging Mech Dis, DOI://10.1038/s41514-017-0009-8 (2017)
Pandemic (H1N1) 2009 influenza A virus infection associated with respiratory signs in sloth bears (Melursus ursinus) Boedeker, NC; Nelson, MI; Killian, ML; Torchetti, MK; Barthel, T; Murray, S; Zoonoses Public Health, DOI://10.1111/zph.12370 (2017)

Characterizing cis-regulatory variation in the transcriptome of histologically normal and tumor-derived pancreatic tissues Zhang, M; Lykke-Andersen, S; Zhu, B et al. Gut, DOI://10.1136/gutjnl-2016-313146 (2017)
Actin Filament Strain Promotes Severing and Cofilin Dissociation Schramm, AC; Hocky, GM; Voth, GA; Blanchoin, L; Martiel, JL; De La Cruz, EM; Biophys. J., DOI://10.1016/j.bpj.2017.05.016 (2017)
Insights into the binding mode of MEK type-III inhibitors. A step towards discovering and designing allosteric kinase inhibitors across the human kinome Zhao, Z; Xie, L; Bourne, PE; PLoS ONE, DOI://10.1371/journal.pone.0179936 (2017)
Genome-Wide Association Study to Identify Susceptibility Loci That Modify Radiation-Related Risk for Breast Cancer After Childhood Cancer Lindsay M. Morton Joshua N. Sampson Gregory T. Armstrong et al. J. Natl. Cancer. Inst., DOI: https://doi.org/10.1093/jnci/djx058 (2017)
The Transcription Factor T-bet Limits Amplification of Type I IFN Transcriptome and Circuitry in T Helper 1 Cells Iwata, S; Mikami, Y; Sun, HW et al. Immunity, DOI://10.1016/j.immuni.2017.05.005 (2017)
Flexible-Body Motions of Calmodulin and the Farnesylated Hypervariable Region Yield a High-Affinity Interaction Enabling K-Ras4B Membrane Extraction Jang, H; Banerjee, A; Chavan, T; Gaponenko, V; Nussinov, R; J. Biol. Chem., DOI://10.1074/jbc.M117.785063 (2017)
The Transcriptome of the Didelphis virginiana Opossum Kidney OK Proximal Tubule Cell Line Eshbach, ML; Sethi, R; Avula, R et al. Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00228.2017 (2017)
Graphite-Templated Amyloid Nanostructures Formed by A Potential Pentapeptide Inhibitor for Alzheimer's disease: A Combined Study of Real-Time Atomic Force Microscopy and Molecular Dynamics Simulations Li, N; Jang, H; Yuan, M et al. Langmuir, DOI://10.1021/acs.langmuir.7b00414 (2017)
Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study Noyce, AJ; Kia, DA; Hemani, G et al. PLoS Med., DOI://10.1371/journal.pmed.1002314 (2017)
Socioeconomic disadvantage, gestational immune activity, and neurodevelopment in early childhood Gilman, SE; Hornig, M; Ghassabian, A et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1617698114 (2017)
Workflow and web application for annotating NCBI BioProject transcriptome data Vera Alvarez, R; Medeiros Vidal, N; Garzón-Martínez, GA; Barrero, LS; Landsman, D; Mariño-Ramírez, L; Database (Oxford), DOI://10.1093/database/bax008 (2017)
NeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases Blauwendraat, C; Faghri, F; Pihlstrom, L et al. Neurobiol. Aging, DOI://10.1016/j.neurobiolaging.2017.05.009 (2017)

Overexpression of ATP-Binding Cassette Subfamily G Member 2 Confers Resistance to Phosphatidylinositol 3-Kinase Inhibitor PF-4989216 in Cancer Cells Wu, CP; Murakami, M; Hsiao, SH et al. Mol. Pharm., DOI://10.1021/acs.molpharmaceut.7b00277 (2017)
Intrinsic protein disorder in oncogenic KRAS signaling Nussinov, R; Jang, H; Tsai, CJ et al. Cell. Mol. Life Sci., DOI://10.1007/s00018-017-2564-3 (2017)
Mitochondrial respiration and ROS emission during β-oxidation in the heart: An experimental-computational study Cortassa, S; Sollott, SJ; Aon, MA; PLoS Comput. Biol., DOI://10.1371/journal.pcbi.1005588 (2017)
Heightened amygdala responsiveness in s-carriers of 5-HTTLPR genetic polymorphism reflects enhanced cortical rather than subcortical inputs: An MEG study Luo, Q; Holroyd, T; Mitchell, D et al. Hum Brain Mapp, DOI://10.1002/hbm.23616 (2017)
Monte Carlo simulations of randomized clinical trials in epilepsy DM Goldenholz, J Tharayil, R Moss, E Myers, WH Theodore Annals of Clinical and Translational Neurology, DOI: 10.1002/acn3.426 (2017)
Prostate Cancer: A Correlative Study of Multiparametric MR Imaging and Digital Histopathology Kwak, JT; Sankineni, S; Xu, S et al. Radiology, DOI://10.1148/radiol.2017160906 (2017)

Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31 Freeman, LA; Demosky, SJ; Konaklieva, M et al. J. Pharmacol. Exp. Ther., DOI://10.1124/jpet.117.240457 (2017)
High-fidelity PCR enzyme with DNA-binding domain facilitates de novo gene synthesis Dolgova, AS; Stukolova, OA; 3 Biotech, DOI://10.1007/s13205-017-0745-2 (2017)
Mediator binds to boundaries of chromosomal interaction domains and to proteins involved in DNA looping, RNA metabolism, chromatin remodeling, and actin assembly Chereji, RV; Bharatula, V; Elfving, N et al. Nucleic Acids Res., DOI://10.1093/nar/gkx491 (2017)
Release of Cytochrome C from Bax Pores at the Mitochondrial Membrane Zhang, M; Zheng, J; Nussinov, R; Ma, B; Sci Rep, DOI://10.1038/s41598-017-02825-7 (2017)
Threat of shock increases excitability and connectivity of the intraparietal sulcus Balderston, NL; Hale, E; Hsiung, A et al. Elife, DOI://10.7554/eLife.23608 (2017)
Identification and Analysis of Protein Phosphorylation by Mass Spectrometry DE McNulty, TW Sikorski, RS Annan in 'Analysis of Protein Post-Translational Modifications by , ed John R. Griffiths, Richard D. Unwin. Wiley (2017)

Whole-brain connectivity dynamics reflect both task-specific and individual-specific modulation: A multitask study Xie, H; Calhoun, VD; Gonzalez-Castillo, J et al. Neuroimage, DOI://10.1016/j.neuroimage.2017.05.050 (2017)
Phosphorylated SIRT1 associates with replication origins to prevent excess replication initiation and preserve genomic stability Utani, K; Fu, H; Jang, SM et al. Nucleic Acids Res., DOI://10.1093/nar/gkx468 (2017)
Combined single molecule experimental and computational approaches for understanding the unfolding pathway of a viral translation enhancer that participates in a conformational switch Le, MT; Kasprzak, WK; Shapiro, BA; Simon, AE; RNA Biol, DOI://10.1080/15476286.2017.1325069 (2017)
Tumor-Infiltrating Lymphocyte Therapy and Neoantigens Robbins, PF Cancer J, DOI://10.1097/PPO.0000000000000267 (2017)
Deficiency of Complement 1r Subcomponent in Early-Onset Systemic Lupus Erythematosus: The Role of Disease-Modifying Alleles in a Monogenic Disease Demirkaya, E; Zhou, Q; Smith, CK et al. , DOI://10.1002/art.40158 (2017)
Dynamic enhancer function in the chromatin context Goldstein, I; Hager, GL; Wiley Interdiscip Rev Syst Biol Med, DOI://10.1002/wsbm.1390 (2017)

PDEδ Binding to Ras Isoforms Provides a Route to Proper Membrane Localization Muratcioglu, S; Jang, H; Gursoy, A; Keskin, O; Nussinov, R; J Phys Chem B, DOI://10.1021/acs.jpcb.7b03035 (2017)
Bivariate Genomic Footprinting Detects Changes in Transcription Factor Activity Baek, S; Goldstein, I; Hager, GL; Cell Rep, DOI://10.1016/j.celrep.2017.05.003 (2017)
Mechanics of post-fusion exocytotic vesicle Stephens, T; Wu, Z; Liu, J; Phys Biol, DOI://10.1088/1478-3975/aa6ad6 (2017)
BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency Afzali, B; Grönholm, J; Vandrovcova, J et al. Nat. Immunol., DOI://10.1038/ni.3753 (2017)
Brownian ratchet mechanisms of ParA-mediated partitioning Hu, L; Vecchiarelli, AG; Mizuuchi, K; Neuman, KC; Liu, J; Plasmid, DOI://10.1016/j.plasmid.2017.05.002 (2017)
Pathology of callosal damage in ALS: An ex-vivo, 7 T diffusion tensor MRI study Agustin M. Cardenas, Joelle E. Sarlls, Justin Y. Kwan, Devin Bageac, Zachary S. Gala, Laura E. Danielian, Abhik Ray-Chaudhury, Hao-Wei Wang, Karla L. Miller, Sean Foxley, Saad Jbabdid, Robert C. Welsh, Mary Kay Floeter NeuroImage: Clinical, doi://10.1016/j.nicl.2017.04.024 (2017)
Unsupervised Joint Mining of Deep Features and Image Labels for Large-Scale Radiology Image Categorization and Scene Recognition Xiaosong Wang, Le Lu, Hoo-chang Shin, Lauren Kim, Mohammadhadi Bagheri, Isabella Nogues, Jianhua Yao, Ronald M. Summers IEEE Winter Conference on Applications of Computer Vision, DOI 10.1109/WACV.2017.116 (2017)
Simulating clinical trials with and without intracranial EEG data Goldenholz D, Tharayil J, Kuzniecky R, et al. Epilepsia Open, DOI: 10.1002/epi4.12038 (2017)
Drosophila melanogaster positive transcriptional elongation factors regulate metabolic and sex-biased expression in adults Yang, H; Basquin, D; Pauli, D; Oliver, B; BMC Genomics, DOI://10.1186/s12864-017-3755-x (2017)
Pias3 is necessary for dorso-ventral patterning and visual response of retinal cones but is not required for rod photoreceptor differentiation Campla, CK; Breit, H; Dong, L; Gumerson, JD; Roger, JE; Swaroop, A; Biol Open, DOI://10.1242/bio.024679 (2017)
Human ancestry correlates with language and reveals that race is not an objective genomic classifier Baker, JL; Rotimi, CN; Shriner, D; Sci Rep, DOI://10.1038/s41598-017-01837-7 (2017)
Conformational Changes in Active and Inactive States of Human PP2Cα Characterized by Hydrogen/Deuterium Exchange-Mass Spectrometry Mazur, SJ; Gallagher, ES; Debnath, S et al. Biochemistry, DOI://10.1021/acs.biochem.6b01220 (2017)
A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated with Reduced Energy Expenditure in American Indians Piaggi, P; Masindova, I; Muller, YL et al. Diabetes, DOI://10.2337/db16-1565 (2017)
Molecular codes for cell type specification in Brn3 retinal ganglion cells Sajgo, S; Ghinia, MG; Brooks, M et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1618551114 (2017)
A population MRI brain template and analysis tools for the macaque Seidlitz, J; Sponheim, C; Glen, D et al. Neuroimage, DOI://10.1016/j.neuroimage.2017.04.063 (2017)
Calmodulin and PI3K Signaling in KRAS Cancers Nussinov, R; Wang, G; Tsai, CJ et al. Trends Cancer, DOI://10.1016/j.trecan.2017.01.007 (2017)
fastMitoCalc: an ultra-fast program to estimate mitochondrial DNA copy number from whole-genome sequences Qian, Y; Butler, TJ; Opsahl-Ong, K et al. Bioinformatics, DOI://10.1093/bioinformatics/btw835 (2017)
Median Analysis of Repeated Measures Associated with Recurrent Events in Presence of Terminal Event Sundaram, R; Ma, L; Ghoshal, S; Int J Biostat, DOI://10.1515/ijb-2016-0057 (2017)

The isomeric preference of an atypical dopamine transporter inhibitor contributes to its selection of the transporter conformation Abramyan, AM; Stolzenberg, S; Li, Z; Loland, CJ; Noé, F; Shi, L; ACS Chem Neurosci, DOI://10.1021/acschemneuro.7b00094 (2017)
Behavioral and Neural Sustained Attention Deficits in Disruptive Mood Dysregulation Disorder and Attention-Deficit/Hyperactivity Disorder Pagliaccio, D; Wiggins, JL; Adleman, NE et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2017.02.008 (2017)
Synthesis of Dopamine in E.coli Using Plasmid Based Expression System and Its Marked Effect on Host Growth Profiles Das, A; Verma, A; Mukherjee, KJ; Prep. Biochem. Biotechnol., DOI://10.1080/10826068.2017.1320291 (2017)
Immunocompetent mouse allograft models for development of therapies to target breast cancer metastasis Yang, Y; Yang, HH; Hu, Y et al. Oncotarget, DOI://10.18632/oncotarget.15695 (2017)
Transposable elements in the Anopheles funestus transcriptome Fernández-Medina, RD; Carareto, CMA; Struchiner, CJ; Ribeiro, JMC; Genetica, DOI://10.1007/s10709-017-9964-z (2017)
fMRI clustering and false-positive rates Cox, RW; Chen, G; Glen, DR; Reynolds, RC; Taylor, PA; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1614961114 (2017)

Sequence and Structural Analyses Reveal Distinct and Highly Diverse Human CD8(+) TCR Repertoires to Immunodominant Viral Antigens Chen, G; Yang, X; Ko, A et al. Cell Rep, DOI://10.1016/j.celrep.2017.03.072 (2017)
Power Grid Protection of the Muscle Mitochondrial Reticulum Glancy, B; Hartnell, LM; Combs, CA et al. Cell Rep, DOI://10.1016/j.celrep.2017.03.063 (2017)
Brain-derived neurotrophic factor Val(66)Met genotype and ovarian steroids interactively modulate working memory-related hippocampal function in women: a multimodal neuroimaging study Wei, SM; Baller, EB; Kohn, PD et al. Mol. Psychiatry, DOI://10.1038/mp.2017.72 (2017)
The Molecular Revolution in Cutaneous Biology: Investigating the Skin Microbiome Kong, HH; Segre, JA; J. Invest. Dermatol., DOI://10.1016/j.jid.2016.07.045 (2017)
Brownian Ratchet Mechanism for Faithful Segregation of Low-Copy-Number Plasmids Hu, L; Vecchiarelli, AG; Mizuuchi, K; Neuman, KC; Liu, J; Biophys. J., DOI://10.1016/j.bpj.2017.02.039 (2017)
H3K4 demethylase KDM5B regulates global dynamics of transcription elongation and alternative splicing in embryonic stem cells He, R; Kidder, BL; Nucleic Acids Res., DOI://10.1093/nar/gkx251 (2017)
FMRI Clustering in AFNI: False-Positive Rates Redux Cox, RW; Chen, G; Glen, DR; Reynolds, RC; Taylor, PA; Brain Connect, DOI://10.1089/brain.2016.0475 (2017)
A novel perivascular cell population in the zebrafish brain Venero Galanternik, M; Castranova, D; Gore, AV et al. Elife, DOI://10.7554/eLife.24369 (2017)
Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly Schneider, VA; Graves-Lindsay, T; Howe, K et al. Genome Res., DOI://10.1101/gr.213611.116 (2017)
Intrinsic Functional Connectivity of the Central Nucleus of the Amygdala and Bed Nucleus of the Stria Terminalis Gorka, AX; Torrisi, S; Shackman, AJ; Grillon, C; Ernst, M; Neuroimage, DOI://10.1016/j.neuroimage.2017.03.007 (2017)
Hydrophobic-Hydrophilic Forces in Protein Folding Durell, SR; Ben-Naim, A; Biopolymers, DOI://10.1002/bip.23020 (2017)
Molecular convergence in ex vivo models of Diamond-Blackfan anemia O'Brien, KA; Farrar, JE; Vlachos, A et al. Blood, DOI://10.1182/blood-2017-01-760462 (2017)
Detection of genetic loci associated with plasma fetuin-A: A meta-analysis of genome-wide association studies from the CHARGE Consortium Jensen, MK; Jensen, RA; Mukamal, KJ et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddx091 (2017)
A New Natural Product Analog of Blasticidin S Reveals Cellular Uptake Facilitated by the NorA Multidrug Transporter Davison, JR; Lohith, KM; Wang, X et al. Antimicrob. Agents Chemother., DOI://10.1128/AAC.02635-16 (2017)
Retrospective correction of frequency drift in spectral editing: The GABA editing example van der Veen, JW; Marenco, S; Berman, KF; Shen, J; NMR Biomed, DOI://10.1002/nbm.3725 (2017)
A big data approach to the development of mixed-effects models for seizure count data Tharayil, JJ; Chiang, S; Moss, R; Stern, JM; Theodore, WH; Goldenholz, DM; Epilepsia, DOI://10.1111/epi.13727 (2017)
Engineering efficient production of itaconic acid from diverse substrates in Escherichia coli Chang, P; Chen, GS; Chu, HY; Lu, KW; Shen, CR; J. Biotechnol., DOI://10.1016/j.jbiotec.2017.03.026 (2017)
REEP6 mediates trafficking of a subset of Clathrin-coated vesicles and is critical for rod photoreceptor function and survival Veleri, S; Nellissery, J; Mishra, B et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddx111 (2017)

Multi-echo fMRI: A review of applications in fMRI denoising and analysis of BOLD signals Kundu, P; Voon, V; Balchandani, P; Lombardo, MV; Poser, BA; Bandettini, PA; Neuroimage, DOI://10.1016/j.neuroimage.2017.03.033 (2017)
Stable functional networks exhibit consistent timing in the human brain Chapeton, JI; Inati, SK; Zaghloul, KA; Brain, DOI://10.1093/brain/aww337 (2017)
Characterization of four arginine kinases in the ciliate Paramecium tetraurelia: Investigation on the substrate inhibition mechanism Yano, D; Suzuki, T; Hirokawa, S; Fuke, K; Suzuki, T; Int. J. Biol. Macromol., DOI://10.1016/j.ijbiomac.2017.03.133 (2017)
An investigation of doubt in obsessive-compulsive disorder Samuels, J; Bienvenu, OJ; Krasnow, J et al. Compr Psychiatry, DOI://10.1016/j.comppsych.2017.03.004 (2017)
Gramicidin A Channel Formation Induces Local Lipid Redistribution II: A 3D Continuum Elastic Model Sodt, AJ; Beaven, AH; Andersen, OS; Im, W; Pastor, RW; Biophys. J., DOI://10.1016/j.bpj.2017.01.035 (2017)
APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast Saini, N; Roberts, SA; Sterling, JF; Malc, EP; Mieczkowski, PA; Gordenin, DA; DNA Repair (Amst.), DOI://10.1016/j.dnarep.2017.03.003 (2017)
Automatic MR prostate segmentation by deep learning with holistically-nested networks Ruida Cheng ; Holger R. Roth ; Nathan Lay ; Le Lu ; Baris Turkbey ; William Gandler ; Evan S. McCreedy ; Peter Choyke ; Ronald M. Summers ; Matthew J. McAuliffe Proc. SPIE 10133, Medical Imaging 2017, doi:10.1117/12.2254558 (2017)
Macrophilone A: Structure Elucidation, Total Synthesis, and Functional Evaluation of a Biologically Active Iminoquinone from the Marine Hydroid Macrorhynchia philippina Zlotkowski, K; Hewitt, WM; Yan, P et al. Org. Lett., DOI://10.1021/acs.orglett.7b00496 (2017)
Common and rare exonic MUC5B variants associated with type 2 diabetes in Han Chinese Chen, G; Zhang, Z; Adebamowo, SN et al. PLoS ONE, DOI://10.1371/journal.pone.0173784 (2017)
Korean Pediatric and Adult Head Computational Phantoms and Application to Photon Specific Absorbed Fractions Calculations Villoing, D; McMillan, D; Kim, KP et al. Radiat Prot Dosimetry, DOI://10.1093/rpd/ncx009 (2017)
Expressed Structurally-stable Inverted Duplicates in Mammalian Genomes as Functional Noncoding Elements Chen, ZX; Oliver, B; Zhang, YE; Gao, G; Long, M; Genome Biol Evol, DOI://10.1093/gbe/evx054 (2017)
Flexible CRISPR library construction using parallel oligonucleotide retrieval Read, A; Gao, S; Batchelor, E; Luo, J; Nucleic Acids Res., DOI://10.1093/nar/gkx181 (2017)

Functional assessment of CTCF sites at cytokine-sensing mammary enhancers using CRISPR/Cas9 gene editing in mice Lee, HK; Willi, M; Wang, C et al. Nucleic Acids Res., DOI://10.1093/nar/gkx185 (2017)
DNase-active TREX1 frame-shift mutants induce serologic autoimmunity in mice Sakai, T; Miyazaki, T; Shin, DM et al. J. Autoimmun., DOI://10.1016/j.jaut.2017.03.001 (2017)
Determining Cysteines Available for Covalent Inhibition Across the Human Kinome Zhao, Z; Liu, Q; Bliven, S; Xie, L; Bourne, PE; J. Med. Chem., DOI://10.1021/acs.jmedchem.6b01815 (2017)
Whole-Exome Sequencing for Diagnosis of Turner Syndrome: Toward Next-Generation Sequencing and Newborn Screening Murdock, DR; Donovan, FX; Chandrasekharappa, SC et al. J. Clin. Endocrinol. Metab., DOI://10.1210/jc.2016-3414 (2017)
The Role of TM5 in Na2 Release and the Conformational Transition of Neurotransmitter:Sodium Symporters toward the Inward-Open State Stolzenberg, S; Li, Z; Quick, M et al. J. Biol. Chem., DOI://10.1074/jbc.M116.757153 (2017)
Neuroanatomic, epigenetic and genetic differences in monozygotic twins discordant for attention deficit hyperactivity disorder Chen, YC; Sudre, G; Sharp, W et al. Mol. Psychiatry, DOI://10.1038/mp.2017.45 (2017)
Predicting drug-drug interactions through drug structural similarities and interaction networks incorporating pharmacokinetics and pharmacodynamics knowledge Takeda, T; Hao, M; Cheng, T; Bryant, SH; Wang, Y; J Cheminform, DOI://10.1186/s13321-017-0200-8 (2017)
Modulation of opioid receptor affinity and efficacy via N-substitution of 9β-hydroxy-5-(3-hydroxyphenyl)morphan: Synthesis and computer simulation study Truong, PM; Hassan, SA; Lee, YS et al. Bioorg. Med. Chem., DOI://10.1016/j.bmc.2017.02.064 (2017)
Computational Study of the Forces Driving Aggregation of Ultrasmall Nanoparticles in Biological Fluids Hassan, SA ACS Nano, DOI://10.1021/acsnano.7b00981 (2017)
Identification of β-Catenin-Interacting Proteins in Nuclear Fractions of Native Rat Collecting Duct Cells Hwang, JR; Chou, CL; Medvar, B; Knepper, MA; Jung, HJ; Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00054.2017 (2017)
Canu: scalable and accurate long-read assembly via adaptive k-mer weighting and repeat separation Koren, S; Walenz, BP; Berlin, K; Miller, JR; Bergman, NH; Phillippy, AM; Genome Res., DOI://10.1101/gr.215087.116 (2017)
Whole exome sequencing in the Framingham Heart Study identifies rare variation in HYAL2 that influences platelet aggregation Eicher, JD; Chen, MH; Pitsillides, AN et al. Thromb. Haemost., DOI://10.1160/TH16-09-0677 (2017)
BTBD18 Regulates a Subset of piRNA-Generating Loci through Transcription Elongation in Mice Zhou, L; Canagarajah, B; Zhao, Y et al. Dev. Cell, DOI://10.1016/j.devcel.2017.02.007 (2017)
A large outbreak of acute gastroenteritis in Shippensburg, Pennsylvania, 1972 revisited: evidence for common source exposure to a recombinant GII.Pg/GII.3 norovirus Johnson, JA; Parra, GI; Levenson, EA; Green, KY; Epidemiol. Infect., DOI://10.1017/S0950268817000498 (2017)
Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits Yao, C; Joehanes, R; Johnson, AD et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2017.02.003 (2017)
Effect of Detergent Micelle Environment on P-glycoprotein (ABCB1)-Ligand Interactions Shukla, S; Abel, B; Chufan, EE; Ambudkar, SV; J. Biol. Chem., DOI://10.1074/jbc.M116.771634 (2017)
Single-molecule sequencing and chromatin conformation capture enable de novo reference assembly of the domestic goat genome Bickhart, DM; Rosen, BD; Koren, S et al. Nat. Genet., DOI://10.1038/ng.3802 (2017)
Analysis of large versus small dogs reveals three genes on the canine X chromosome associated with body weight, muscling and back fat thickness Plassais, J; Rimbault, M; Williams, FJ; Davis, BW; Schoenebeck, JJ; Ostrander, EA; PLoS Genet., DOI://10.1371/journal.pgen.1006661 (2017)

SMYD5 regulates H4K20me3-marked heterochromatin to safeguard ES cell self-renewal and prevent spurious differentiation Kidder, BL; Hu, G; Cui, K; Zhao, K; Epigenetics Chromatin, DOI://10.1186/s13072-017-0115-7 (2017)
Genome-wide siRNA screen of genes regulating the LPS-induced TNF-α response in human macrophages Sun, J; Katz, S; Dutta, B; Wang, Z; Fraser, ID; Sci Data, DOI://10.1038/sdata.2017.7 (2017)
Genome-wide siRNA screen of genes regulating the LPS-induced NF-κB and TNF-α responses in mouse macrophages Li, N; Katz, S; Dutta, B; Benet, ZL; Sun, J; Fraser, ID; Sci Data, DOI://10.1038/sdata.2017.8 (2017)
Permanganate/S1 Nuclease Footprinting Reveals Non-B DNA Structures with Regulatory Potential across a Mammalian Genome Kouzine, F; Wojtowicz, D; Baranello, L et al. Cell Syst, DOI://10.1016/j.cels.2017.01.013 (2017)
Circulating tumor cells capture disease evolution in advanced prostate cancer Lack, J; Gillard, M; Cam, M; Paner, GP; VanderWeele, DJ; J Transl Med, DOI://10.1186/s12967-017-1138-3 (2017)
Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer Liu, Q; Acharya, P; Dolan, MA et al. Nat. Struct. Mol. Biol., DOI://10.1038/nsmb.3382 (2017)

The effects of shared information on semantic calculations in the gene ontology Bible, PW; Sun, HW; Morasso, MI; Loganantharaj, R; Wei, L; Comput Struct Biotechnol J, DOI://10.1016/j.csbj.2017.01.009 (2017)
Ultra-High-Field fMRI Reveals a Role for the Subiculum in Scene Perceptual Discrimination Hodgetts, CJ; Voets, NL; Thomas, AG; Clare, S; Lawrence, AD; Graham, KS; J. Neurosci., DOI://10.1523/JNEUROSCI.3225-16.2017 (2017)
Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies Hedman, ÅK; Mendelson, MM; Marioni, RE et al. Circ Cardiovasc Genet, DOI://10.1161/CIRCGENETICS.116.001487 (2017)
Circulating miRNA Associated with Posttraumatic Stress Disorder in a Cohort of Military Combat Veterans Christiana G. Martin, Hyungsuk Kim, Sijung Yun, Whitney Livingston, Joseph Fetta, Vincent Mysliwiec, Tristin Baxter, Jessica M. Gill Psychiatry Research, doi://10.1016/j.psychres.2017.01.081 (2017)
The dynamic mechanism of RASSF5 and MST kinase activation by Ras Liao, TJ; Jang, H; Tsai, CJ; Fushman, D; Nussinov, R; Phys Chem Chem Phys, DOI://10.1039/c6cp08596b (2017)
Genome-Wide Identification of Basic Helix-Loop-Helix and NF-1 Motifs Underlying GR Binding Sites in Male Rat Hippocampus Pooley, JR; Flynn, BP; Grøntved, L et al. Endocrinology, DOI://10.1210/en.2016-1929 (2017)

Somatic mutations in murine models of leukemia and lymphoma: Disease specificity and clinical relevance Goldberg, L; Gough, SM; Lee, F et al. Genes Chromosomes Cancer, DOI://10.1002/gcc.22451 (2017)
Multivariate meta-analysis with an increasing number of parameters Boca, SM; Pfeiffer, RM; Sampson, JN; Biom J, DOI://10.1002/bimj.201600013 (2017)
Anopheline salivary protein genes and gene families: an evolutionary overview after the whole genome sequence of sixteen Anopheles species Arcà, B; Lombardo, F; Struchiner, CJ; Ribeiro, JM; BMC Genomics, DOI://10.1186/s12864-017-3579-8 (2017)
Genetic regulatory signatures underlying islet gene expression and type 2 diabetes Varshney, A; Scott, LJ; Welch, RP et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1621192114 (2017)
A novel DLX3-PKC integrated signaling network drives keratinocyte differentiation Palazzo, E; Kellett, MD; Cataisson, C et al. Cell Death Differ., DOI://10.1038/cdd.2017.5 (2017)
Folding behavior of a T-shaped, ribosome-binding translation enhancer implicated in a wide-spread conformational switch Le, MT; Kasprzak, WK; Kim, T et al. Elife, DOI://10.7554/eLife.22883 (2017)

Thiazole-valine peptidomimetic (TTT-28) antagonizes multidrug resistance in vitro and in vivo by selectively inhibiting the efflux activity of ABCB1 Wang, YJ; Patel, BA; Anreddy, N et al. Sci Rep, DOI://10.1038/srep42106 (2017)
Messenger RNA and MicroRNA transcriptomic signatures of cardiometabolic risk factors McManus, DD; Rong, J; Huan, T et al. BMC Genomics, DOI://10.1186/s12864-017-3533-9 (2017)
iPSCs and fibroblast subclones from the same fibroblast population contain comparable levels of sequence variations Kwon, EM; Connelly, JP; Hansen, NF et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1616035114 (2017)
Dense genotyping of immune-related loci implicates host responses to microbial exposure in Behçet's disease susceptibility Takeuchi, M; Mizuki, N; Meguro, A et al. Nat. Genet., DOI://10.1038/ng.3786 (2017)
Insights from NMR Spectroscopy into the Conformational Properties of Man-9 and Its Recognition by Two HIV Binding Proteins Shahzad-Ul-Hussan, S; Sastry, M; Lemmin, T et al. Chembiochem, DOI://10.1002/cbic.201600665 (2017)
MNase-Sensitive Complexes in Yeast: Nucleosomes and Non-histone Barriers Chereji, RV; Ocampo, J; Clark, DJ; Mol. Cell, DOI://10.1016/j.molcel.2016.12.009 (2017)

Amyloid β Ion Channels in a Membrane Comprising Brain Total Lipid Extracts Lee, J; Kim, YH; T Arce, F et al. ACS Chem Neurosci, DOI://10.1021/acschemneuro.7b00006 (2017)
Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing Jansen, IE; Ye, H; Heetveld, S et al. Genome Biol., DOI://10.1186/s13059-017-1147-9 (2017)
Secretory Expression and Characterization of Chinese Narcissus GNA-Like Lectin in Pichia pastoris Li, X; Zhang, P; Zhang, N et al. Appl. Biochem. Biotechnol., DOI://10.1007/s12010-017-2408-5 (2017)
Hybrid assembly of the large and highly repetitive genome of Aegilops tauschii, a progenitor of bread wheat, with the MaSuRCA mega-reads algorithm Zimin, AV; Puiu, D; Luo, MC et al. Genome Res., DOI://10.1101/gr.213405.116 (2017)
Hedgehog Signaling Inhibitors Fail to Reduce Merkel Cell Carcinoma Viability Carroll, TM; Williams, JS; Daily, K et al. J. Invest. Dermatol., DOI://10.1016/j.jid.2017.01.008 (2017)
Differential methylation of genes in individuals exposed to maternal diabetes in utero Chen, P; Piaggi, P; Traurig, M et al. Diabetologia, DOI://10.1007/s00125-016-4203-1 (2017)

ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans Lyons, JJ; Liu, Y; Ma, CA et al. J. Exp. Med., DOI://10.1084/jem.20161435 (2017)
Frequent inactivating germline mutations in DNA repair genes in patients with Ewing sarcoma Brohl, AS; Patidar, R; Turner, CE et al. Genet. Med., DOI://10.1038/gim.2016.206 (2017)
Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies Joehanes, R; Zhang, X; Huan, T et al. Genome Biol., DOI://10.1186/s13059-016-1142-6 (2017)
Gleason Score 7 Prostate Cancers Emerge through Branched Evolution of Clonal Gleason Pattern 3 and 4 Sowalsky, AG; Kissick, HT; Gerrin, SJ et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-16-2414 (2017)
Dose coefficients for ICRP reference pediatric phantoms exposed to idealised external gamma fields Chang, LA; Simon, SL; Jorgensen, TJ; Schauer, DA; Lee, C; J Radiol Prot, DOI://10.1088/1361-6498/aa559e (2017)
Actin dynamics and competition for myosin monomer govern the sequential amplification of myosin filaments Beach, JR; Bruun, KS; Shao, L et al. Nat. Cell Biol., DOI://10.1038/ncb3463 (2017)

Functionally-interdependent shape-switching nanoparticles with controllable properties Halman, JR; Satterwhite, E; Roark, B et al. Nucleic Acids Res., DOI://10.1093/nar/gkx008 (2017)
SDHD promoter mutations ablate GABP transcription factor binding in melanoma Zhang, T; Xu, M; Makowski, MM et al. Cancer Res., DOI://10.1158/0008-5472.CAN-16-0919 (2017)
Static and Evolving Norovirus Genotypes: Implications for Epidemiology and Immunity Parra, GI; Squires, RB; Karangwa, CK et al. PLoS Pathog., DOI://10.1371/journal.ppat.1006136 (2017)
Novel genetic loci associated with hippocampal volume Hibar, DP; Adams, HH; Jahanshad, N et al. Nat Commun, DOI://10.1038/ncomms13624 (2017)
Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach Mendelson, MM; Marioni, RE; Joehanes, R et al. PLoS Med., DOI://10.1371/journal.pmed.1002215 (2017)
Quantitative stability of hematopoietic stem and progenitor cell clonal output in rhesus macaques receiving transplants Koelle, SJ; Espinoza, DA; Wu, C et al. Blood, DOI://10.1182/blood-2016-07-728691 (2017)

Designer Drugs 2.0 Huestis, MA; Tyndale, RF; Clin. Pharmacol. Ther., DOI://10.1002/cpt.575 (2017)
Sequence of Reston Virus Isolate AZ-1435, an Ebolavirus Isolate Obtained during the 1989-1990 Reston Virus Epizootic in the United States Cornish, JP; Diaz, L; Ricklefs, SM et al. Genome Announc, DOI://10.1128/genomeA.01448-16 (2017)
An Estimation of Hybrid Quantum Mechanical Molecular Mechanical Polarization Energies for Small Molecules Using Polarizable Force-Field Approaches Huang, J; Mei, Y; König, G et al. J Chem Theory Comput, DOI://10.1021/acs.jctc.6b01125 (2017)
Familial Mutations May Switch Conformational Preferences in α-Synuclein Fibrils Xu, L; Ma, B; Nussinov, R; Thompson, D; ACS Chem Neurosci, DOI://10.1021/acschemneuro.6b00406 (2017)
Identifying Host Genetic Variants Associated with Microbiome Composition by Testing Multiple Beta Diversity Matrices Hua, X; Goedert, JJ; Landi, MT; Shi, J; Hum. Hered., DOI://10.1159/000448733 (2017)
High fat diet-induced changes of mouse hepatic transcription and enhancer activity can be reversed by subsequent weight loss Siersbæk, M; Varticovski, L; Yang, S et al. Sci Rep, DOI://10.1038/srep40220 (2017)

The primacy of NF1 loss as the driver of tumorigenesis in neurofibromatosis type 1-associated plexiform neurofibromas Pemov, A; Li, H; Patidar, R et al. Oncogene, DOI://10.1038/onc.2016.464 (2017)
Performing Skin Microbiome Research: A Method to the Madness Kong, HH; Andersson, B; Clavel, T et al. J. Invest. Dermatol., DOI://10.1016/j.jid.2016.10.033 (2017)
Characterization of the disassembly and reassembly of the HBV glycoprotein surface antigen, a pliable nanoparticle vaccine platform Gallagher, JR; Torian, U; McCraw, DM; Harris, AK; Virology, DOI://10.1016/j.virol.2016.12.025 (2017)
The Papillomavirus Episteme: a major update to the papillomavirus sequence database Van Doorslaer, K; Li, Z; Xirasagar, S et al. Nucleic Acids Res., DOI://10.1093/nar/gkw879 (2017)
Genetic stability of genome-scale deoptimized RNA virus vaccine candidates under selective pressure Le Nouën, C; McCarty, T; Brown, M et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1619242114 (2017)
Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting Doria-Rose, NA; Altae-Tran, HR; Roark, RS et al. PLoS Pathog., DOI://10.1371/journal.ppat.1006148 (2017)
An insight into the sialome of Hyalomma excavatum Ribeiro, JM; Slovák, M; Francischetti, IM; Ticks Tick Borne Dis, DOI://10.1016/j.ttbdis.2016.08.011 (2017)
Data integration in physiology using Bayes' rule and minimum Bayes' factors: deubiquitylating enzymes in the renal collecting duct Xue, Z; Chen, JX; Zhao, Y; Medvar, B; Knepper, MA; Physiol. Genomics, DOI://10.1152/physiolgenomics.00120.2016 (2017)
Human Neuronal Calcium Sensor-1 Protein Avoids Histidine Residues To Decrease pH Sensitivity Gong, Y; Zhu, Y; Zou, Y; Ma, B; Nussinov, R; Zhang, Q; J Phys Chem B, DOI://10.1021/acs.jpcb.6b11094 (2017)
Computational models of the neural control of breathing Molkov, YI; Rubin, JE; Rybak, IA; Smith, JC; Wiley Interdiscip Rev Syst Biol Med, DOI://10.1002/wsbm.1371 (2017)
Structural studies of influenza virus RNPs by electron microscopy indicate molecular contortions within NP supra-structures Gallagher, JR; Torian, U; McCraw, DM; Harris, AK; J. Struct. Biol., DOI://10.1016/j.jsb.2016.12.007 (2017)
EBI2 overexpression in mice leads to B1 B-cell expansion and chronic lymphocytic leukemia-like B-cell malignancies Niss Arfelt, K; Barington, L; Benned-Jensen, T et al. Blood, DOI://10.1182/blood-2016-02-697185 (2017)

The cell cycle restricts activation-induced cytidine deaminase activity to early G1 Wang, Q; Kieffer-Kwon, KR; Oliveira, TY et al. J. Exp. Med., DOI://10.1084/jem.20161649 (2017)
Neural Markers in Pediatric Bipolar Disorder and Familial Risk for Bipolar Disorder Wiggins, JL; Brotman, MA; Adleman, NE et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2016.10.009 (2017)
The bald and the beautiful: hairlessness in domestic dog breeds Parker, HG; Harris, A; Dreger, DL; Davis, BW; Ostrander, EA; Philos. Trans. R. Soc. Lond., B, Biol. Sci., DOI://10.1098/rstb.2015.0488 (2017)
ADORA1 mutations are not a common cause of Parkinson's disease and dementia with Lewy bodies Blauwendraat, C; Nalls, MA; Federoff, M et al. Mov. Disord., DOI://10.1002/mds.26886 (2017)
Temporal association of ORCA/LRWD1 to late-firing origins during G1 dictates heterochromatin replication and organization Wang, Y; Khan, A; Marks, AB et al. Nucleic Acids Res., DOI://10.1093/nar/gkw1211 (2017)
Acquired somatic mutations in PNH reveal long-term maintenance of adaptive NK cells independent of HSPCs Corat, MA; Schlums, H; Wu, C et al. Blood, DOI://10.1182/blood-2016-08-734285 (2017)

Whole exome sequencing in 75 high-risk families with validation and replication in independent case-control studies identifies TANGO2, OR5H14, and CHAD as new prostate cancer susceptibility genes Karyadi, DM; Geybels, MS; Karlins, E et al. Oncotarget, DOI://10.18632/oncotarget.13646 (2017)
Long-term monitoring of cardiorespiratory patterns in drug-resistant epilepsy Goldenholz, DM; Kuhn, A; Austermuehle, A et al. Epilepsia, DOI://10.1111/epi.13606 (2017)
Assessing variation across 8 established East Asian loci for type 2 diabetes mellitus in American Indians: Suggestive evidence for new sex-specific diabetes signals in GLIS3 and ZFAND3 Muller, YL; Piaggi, P; Chen, P et al. Diabetes Metab. Res. Rev., DOI://10.1002/dmrr.2869 (2017)
Estimating the Heritability of Structural and Functional Brain Connectivity in Families Affected by Attention-Deficit/Hyperactivity Disorder Sudre, G; Choudhuri, S; Szekely, E et al. JAMA Psychiatry, DOI://10.1001/jamapsychiatry.2016.3072 (2017)
Oculocutaneous albinism type 1: link between mutations, tyrosinase conformational stability, and enzymatic activity Dolinska, MB; Kus, NJ; Farney, SK; Wingfield, PT; Brooks, BP; Sergeev, YV; Pigment Cell Melanoma Res, DOI://10.1111/pcmr.12546 (2017)
DLX3-Dependent Regulation of Ion Transporters and Carbonic Anhydrases is Crucial for Enamel Mineralization Duverger, O; Ohara, T; Bible, PW; Zah, A; Morasso, MI; J. Bone Miner. Res., DOI://10.1002/jbmr.3022 (2017)

Untangling the relatedness among correlations, Part II: Inter-subject correlation group analysis through linear mixed-effects modeling Chen, G; Taylor, PA; Shin, YW; Reynolds, RC; Cox, RW; Neuroimage, DOI://10.1016/j.neuroimage.2016.08.029 (2017)
Topographical and physiological differences of the skin mycobiome in health and disease Jo, JH; Kennedy, EA; Kong, HH; Virulence, DOI://10.1080/21505594.2016.1249093 (2017)
Empirically derived patterns of psychiatric symptoms in youth: A latent profile analysis Kircanski, K; Zhang, S; Stringaris, A et al. J Affect Disord, DOI://10.1016/j.jad.2016.09.016 (2017)
Absolute binding free energy calculations of CBClip host-guest systems in the SAMPL5 blind challenge Lee, J; Tofoleanu, F; Pickard, FC et al. J. Comput. Aided Mol. Des., DOI://10.1007/s10822-016-9968-2 (2017)
Immobilized MutS-Mediated Error Removal of Microchip-Synthesized DNA Wan, W; Wang, D; Gao, X; Hong, J; Methods Mol. Biol., DOI://10.1007/978-1-4939-6343-0_17 (2017)
Perfluoroalkyl Chemicals, Menstrual Cycle Length, and Fecundity: Findings from a Prospective Pregnancy Study Lum, KJ; Sundaram, R; Barr, DB; Louis, TA; Buck Louis, GM; Epidemiology, DOI://10.1097/EDE.0000000000000552 (2017)

Anxiety Patients Show Reduced Working Memory Related dlPFC Activation During Safety and Threat Balderston, NL; Vytal, KE; O'Connell, K et al. Depress Anxiety, DOI://10.1002/da.22518 (2017)

2016 (408 papers)

Can dielectric spheres accurately model atomic-scale interactions Obolensky, OI; Doerr, TP; Ogurtsov, AY; Yu, YK; Europhys Lett, DOI://10.1209/0295-5075/116/24003 (2016)
Direct Regulation of Alternative Splicing by SMAD3 through PCBP1 Is Essential to the Tumor-Promoting Role of TGF-β Tripathi, V; Sixt, KM; Gao, S et al. Mol. Cell, DOI://10.1016/j.molcel.2016.09.013 (2016)
Functional connectivity during masked and unmasked face emotion processing in bipolar disorder Tseng, WL; Thomas, LA; Harkins, E et al. Psychiatry Res Neuroimaging, DOI://10.1016/j.pscychresns.2016.10.006 (2016)
Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase Puppala, AK; French, RL; Matthies, D; Baxa, U; Subramaniam, S; Simonović, M; Sci Rep, DOI://10.1038/srep32563 (2016)
Ionic immune suppression within the tumour microenvironment limits T cell effector function Eil, R; Vodnala, SK; Clever, D et al. Nature, DOI://10.1038/nature19364 (2016)

Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche Clever, D; Roychoudhuri, R; Constantinides, MG et al. Cell, DOI://10.1016/j.cell.2016.07.032 (2016)
The transcription factor BACH2 promotes tumor immunosuppression Roychoudhuri, R; Eil, RL; Clever, D et al. J. Clin. Invest., DOI://10.1172/JCI82884 (2016)
BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers Roychoudhuri, R; Clever, D; Li, P et al. Nat. Immunol., DOI://10.1038/ni.3441 (2016)
Memory T cell-driven differentiation of naive cells impairs adoptive immunotherapy Klebanoff, CA; Scott, CD; Leonardi, AJ et al. J. Clin. Invest., DOI://10.1172/JCI81217 (2016)
Human-Mouse Chimeras with Normal Expression and Function Reveal That Major Domain Swapping Is Tolerated by P-Glycoprotein (ABCB1) Pluchino, KM; Hall, MD; Moen, JK et al. Biochemistry, DOI://10.1021/acs.biochem.5b01064 (2016)
Drugging Ras GTPase: a comprehensive mechanistic and signaling structural view Lu, S; Jang, H; Gu, S; Zhang, J; Nussinov, R; Chem Soc Rev, DOI://10.1039/c5cs00911a (2016)
Pioneer factors and ATP-dependent chromatin remodeling factors interact dynamically: A new perspective: Multiple transcription factors can effect chromatin pioneer functions through dynamic interactions with ATP-dependent chromatin remodeling factors Swinstead, EE; Paakinaho, V; Presman, DM; Hager, GL; Bioessays, DOI://10.1002/bies.201600137 (2016)
Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant Li, J; Woods, SL; Healey, S et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2016.03.001 (2016)
Deep genome sequencing and variation analysis of 13 inbred mouse strains defines candidate phenotypic alleles, private variation and homozygous truncating mutations Doran, AG; Wong, K; Flint, J; Adams, DJ; Hunter, KW; Keane, TM; Genome Biol., DOI://10.1186/s13059-016-1024-y (2016)
A Small Number of Residues Can Determine if Linker Histones Are Bound On or Off Dyad in the Chromatosome Zhou, BR; Feng, H; Ghirlando, R; Li, S; Schwieters, CD; Bai, Y; J. Mol. Biol., DOI://10.1016/j.jmb.2016.08.016 (2016)
Comparing Brain Morphometry Across Multiple Childhood Psychiatric Disorders Gold, AL; Brotman, MA; Adleman, NE et al. J Am Acad Child Adolesc Psychiatry, DOI://10.1016/j.jaac.2016.08.008 (2016)
Toward elucidating the heat activation mechanism of the TRPV1 channel gating by molecular dynamics simulation Wen, H; Qin, F; Zheng, W; Proteins, DOI://10.1002/prot.25177 (2016)
Blind prediction of distribution in the SAMPL5 challenge with QM based protomer and pK a corrections Pickard, FC; König, G; Tofoleanu, F et al. J. Comput. Aided Mol. Des., DOI://10.1007/s10822-016-9955-7 (2016)
Identification of therapeutic targets applicable to clinical strategies in ovarian cancer Kim, MK; Caplen, N; Chakka, S et al. BMC Cancer, DOI://10.1186/s12885-016-2675-5 (2016)
Childhood peer network characteristics: genetic influences and links with early mental health trajectories Szekely, E; Pappa, I; Wilson, JD et al. J Child Psychol Psychiatry, DOI://10.1111/jcpp.12493 (2016)
Outcome of the First wwPDB/CCDC/D3R Ligand Validation Workshop Adams, PD; Aertgeerts, K; Bauer, C et al. Structure, DOI://10.1016/j.str.2016.02.017 (2016)
Partition coefficients for the SAMPL5 challenge using transfer free energies Jones, MR; Brooks, BR; Wilson, AK; J. Comput. Aided Mol. Des., DOI://10.1007/s10822-016-9964-6 (2016)
Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III Esser, L; Zhou, F; Zhou, Y et al. J. Biol. Chem., DOI://10.1074/jbc.M116.744391 (2016)

An Open Pilot Study of Training Hostile Interpretation Bias to Treat Disruptive Mood Dysregulation Disorder Stoddard, J; Sharif-Askary, B; Harkins, EA et al. J Child Adolesc Psychopharmacol, DOI://10.1089/cap.2015.0100 (2016)
Estimation of FST and the Impact of de novo Mutation Shriner, D; Chen, G; Adeyemo, A; Rotimi, CN; Hum. Hered., DOI://10.1159/000477782 (2016)
Neuroendocrine Tumor of the Pancreas as a Manifestation of Cowden Syndrome: A Case Report Neychev, V; Sadowski, SM; Zhu, J et al. J. Clin. Endocrinol. Metab., DOI://10.1210/jc.2015-3684 (2016)
Light induced structural changes of the photoprotein mnemiopsin: Characterization and contribution in photoinactivation Pashandi, Z; Molakarimi, M; Sajedi, RH; Taghdir, M; Naderi-Manesh, H; J. Photochem. Photobiol. B, Biol., DOI://10.1016/j.jphotobiol.2016.10.018 (2016)
Robust spike sorting of retinal ganglion cells tuned to spot stimuli Ghahari, A; Badea, TC; Conf Proc IEEE Eng Med Biol Soc, DOI://10.1109/EMBC.2016.7591054 (2016)
Assessing the reproducibility of exome copy number variations predictions Hong, CS; Singh, LN; Mullikin, JC; Biesecker, LG; Genome Med, DOI://10.1186/s13073-016-0336-6 (2016)

Computation of Hydration Free Energies Using the Multiple Environment Single System Quantum Mechanical/Molecular Mechanical Method König, G; Mei, Y; Pickard, FC et al. J Chem Theory Comput, DOI://10.1021/acs.jctc.5b00874 (2016)
Whole Genome Sequencing of Newly Established Pancreatic Cancer Lines Identifies Novel Somatic Mutation (c.2587G>A) in Axon Guidance Receptor Plexin A1 as Enhancer of Proliferation and Invasion Sorber, R; Teper, Y; Abisoye-Ogunniyan, A et al. PLoS ONE, DOI://10.1371/journal.pone.0149833 (2016)
Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data Shi, J; Park, JH; Duan, J et al. PLoS Genet., DOI://10.1371/journal.pgen.1006493 (2016)
Block network mapping approach to quantitative trait locus analysis Shreif, ZZ; Gatti, DM; Periwal, V; BMC Bioinformatics, DOI://10.1186/s12859-016-1351-8 (2016)
Lineage-Specific and Non-specific Cytokine-Sensing Genes Respond Differentially to the Master Regulator STAT5 Zeng, X; Willi, M; Shin, HY; Hennighausen, L; Wang, C; Cell Rep, DOI://10.1016/j.celrep.2016.11.079 (2016)
Meta-analysis of quantitative pleiotropic traits for next-generation sequencing with multivariate functional linear models Chiu, CY; Jung, J; Chen, W et al. Eur. J. Hum. Genet., DOI://10.1038/ejhg.2016.170 (2016)

Towards understanding the structural basis of partial agonism at the dopamine D3 receptor Michino, M; Boateng, CA; Donthamsetti, P et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.6b01148 (2016)
Comparison of parametric and machine methods for variable selection in simulated Genetic Analysis Workshop 19 data Holzinger, ER; Szymczak, S; Malley, J et al. BMC Proc, DOI://10.1186/s12919-016-0021-1 (2016)
From 20th Century Metabolic Wall Charts to 21st Century Systems Biology: Database of Mammalian Metabolic Enzymes Corcoran, CC; Grady, CR; Pisitkun, T; Parulekar, J; Knepper, MA; Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00601.2016 (2016)
Lipid and Peptide Diffusion in Bilayers: The Saffman-Delbrück Model and Periodic Boundary Conditions Venable, RM; Ingólfsson, HI; Lerner, MG et al. J Phys Chem B, DOI://10.1021/acs.jpcb.6b09111 (2016)
DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases Ligthart, S; Marzi, C; Aslibekyan, S et al. Genome Biol., DOI://10.1186/s13059-016-1119-5 (2016)
Structure-Based Scaffold Repurposing for G Protein-Coupled Receptors: Transformation of Adenosine Derivatives into 5HT2B/5HT2C Serotonin Receptor Antagonists Tosh, DK; Ciancetta, A; Warnick, E; Crane, S; Gao, ZG; Jacobson, KA; J. Med. Chem., DOI://10.1021/acs.jmedchem.6b01183 (2016)

Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications Ombrello, MJ; Arthur, VL; Remmers, EF et al. Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2016-210324 (2016)
Mechanisms of Evolution in High-Consequence Drug Resistance Plasmids He, S; Chandler, M; Varani, AM; Hickman, AB; Dekker, JP; Dyda, F; MBio, DOI://10.1128/mBio.01987-16 (2016)
Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study Shi, J; Hua, X; Zhu, B et al. PLoS Med., DOI://10.1371/journal.pmed.1002162 (2016)
Mapping Complex Traits in a Diversity Outbred F1 Mouse Population Identifies Germline Modifiers of Metastasis in Human Prostate Cancer Winter, JM; Gildea, DE; Andreas, JP et al. Cell Syst, DOI://10.1016/j.cels.2016.10.018 (2016)
A comparison study of multivariate fixed models and Gene Association with Multiple Traits (GAMuT) for next-generation sequencing Chiu, CY; Jung, J; Wang, Y et al. Genet. Epidemiol., DOI://10.1002/gepi.22014 (2016)
Sparse multidimensional iterative lineshape-enhanced (SMILE) reconstruction of both non-uniformly sampled and conventional NMR data Ying, J; Delaglio, F; Torchia, DA; Bax, A; J. Biomol. NMR, DOI://10.1007/s10858-016-0072-7 (2016)

Robust skull stripping using multiple MR image contrasts insensitive to pathology Roy, S; Butman, JA; Pham, DL; Neuroimage, DOI://10.1016/j.neuroimage.2016.11.017 (2016)
Association of Irritability and Anxiety With the Neural Mechanisms of Implicit Face Emotion Processing in Youths With Psychopathology Stoddard, J; Tseng, WL; Kim, P et al. JAMA Psychiatry, DOI://10.1001/jamapsychiatry.2016.3282 (2016)
Early generated B1 B cells with restricted BCRs become chronic lymphocytic leukemia with continued c-Myc and low Bmf expression Hayakawa, K; Formica, AM; Brill-Dashoff, J et al. J. Exp. Med., DOI://10.1084/jem.20160712 (2016)
Allosteric control of antibody-prion recognition through oxidation of a disulfide bond between the CH and CL chains Zhao, J; Nussinov, R; Ma, B; Protein Eng. Des. Sel., DOI://10.1093/protein/gzw065 (2016)
High-level expression of improved thermo-stable alkaline xylanase variant in Pichia Pastoris through codon optimization, multiple gene insertion and high-density fermentation Lu, Y; Fang, C; Wang, Q; Zhou, Y; Zhang, G; Ma, Y; Sci Rep, DOI://10.1038/srep37869 (2016)
Molecular Diagnosis of Inherited Retinal Diseases in Indigenous African Populations by Whole-Exome Sequencing Roberts, L; Ratnapriya, R; du Plessis, M; Chaitankar, V; Ramesar, RS; Swaroop, A; Invest. Ophthalmol. Vis. Sci., DOI://10.1167/iovs.16-19785 (2016)
Stage-Specific Transcriptome and Proteome Analyses of the Filarial Parasite Onchocerca volvulus and Its Wolbachia Endosymbiont Bennuru, S; Cotton, JA; Ribeiro, JM et al. MBio, DOI://10.1128/mBio.02028-16 (2016)
NRL-Regulated Transcriptome Dynamics of Developing Rod Photoreceptors Kim, JW; Yang, HJ; Brooks, MJ et al. Cell Rep, DOI://10.1016/j.celrep.2016.10.074 (2016)
Whole-genome sequence, SNP chips and pedigree structure: building demographic profiles in domestic dog breeds to optimize genetic-trait mapping Dreger, DL; Rimbault, M; Davis, BW; Bhatnagar, A; Parker, HG; Ostrander, EA; Dis Model Mech, DOI://10.1242/dmm.027037 (2016)
Integrative network analysis reveals molecular mechanisms of blood pressure regulation Tianxiao Huan, Qingying Meng et al. Mol Syst Biol., doi: 10.15252/msb.20145399 (2016)
C. elegans DAF-2 as a Model for Human Insulin Receptoropathies David A. Bulger, Tetsunari Fukushige, Sijung Yun, Robert K. Semple, John A. Hanover, and Michael W. Krause Genes|Genomes|Genetics, doi:10.1534/g3.116.03718 (2016)
Generation and differentiation of induced pluripotent stem cells reveal ankylosing spondylitis risk gene expression in bone progenitors Gerlinde Layh-Schmitt, Shajia Lum Fatemehm Navid, Stephen R. Brooks, Emily Lazowick, Kathryn M. Davis, Cristina Montagna, Massimo Gadina, Robert A. Colbert Clinical Rheumatology, doi:10.1007/s10067-016-3469-5 (2016)
The genome of Onchocerca volvulus, agent of river blindness Cotton, JA; Bennuru, S; Grote, A et al. Nat Microbiol, DOI://10.1038/nmicrobiol.2016.216 (2016)
Two Na+ Sites Control Conformational Change in a Neurotransmitter Transporter Homolog Sotiria Tavoulari, Eleonora Margheritis, Anu Nagarajan, David C. DeWitt, Yuan -Wei Zhang, Edwin Rosado, Silvia Ravera, Elizabeth Rhoades, Lucy R. Forrest and Gary Rudnick J Biol Chem. , doi: 10.1074/jbc.M115.692012. (2016)
Techniques for blood volume fMRI with VASO: From low-resolution mapping towards sub-millimeter layer-dependent applications Huber, L; Ivanov, D; Handwerker, DA et al. Neuroimage, DOI://10.1016/j.neuroimage.2016.11.039 (2016)
Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity Esser, L; Zhou, F; Pluchino, KM et al. J. Biol. Chem., DOI://10.1074/jbc.M116.755884 (2016)
Physiological basis of vascular autocalibration (VasA): Comparison to hypercapnia calibration methods Kazan, SM; Huber, L; Flandin, G; Ivanov, D; Bandettini, P; Weiskopf, N; Magn Reson Med, DOI://10.1002/mrm.26494 (2016)
Serine/Threonine Phosphatases and Aquaporin-2 Regulation in Renal Collecting Duct Sophia LeMaire, Viswanathan Raghuram, Cameron R. Grady, Christina M. Pickering, Chung-Lin Chou, Ezigbobiara N Umejiego, Mark A. Knepper Am. J. Physiol. - Renal Physiol. , DOI: 10.1152/ajprenal.00455.2016 (2016)

Identification of a novel lipid binding motif in apolipoprotein B by the analysis of hydrophobic cluster domains Scott M. Gordon, Mohsen Pourmousa, Maureen Sampson, Denis Sviridov, Rafique Islam, B. Scott Perrin Jr., Georgina Kemeh, Richard W. Pastor, Alan T. Remaley Biochimica et Biophysica Acta - Membranes, doi://10.1016/j.bbamem.2016.10.019 (2016)
Convergence and Sampling in Determining Free Energy Landscapes for Membrane Protein Association Jan Domanski, George Hedger, Robert B. Best, Phillip James Stansfeld, and Mark S. P. Sansom J. Phys. Chem. B, doi://10.1021/acs.jpcb.6b08445 (2016)
Transcriptome Profiling of NIH3T3 Cell Lines Expressing Opsin and the P23H Opsin Mutant Identifies Candidate Drugs for the Treatment of Retinitis Pigmentosa Yuanyuan Chen, Matthew J. Brooks, Linn Gieser, Anand Swaroop, Krzysztof Palczewski Pharmacological Research, doi://10.1016/j.phrs.2016.10.031 (2016)
RNA-seq analyses of the midgut from blood- and serum-fed Ixodes ricinus ticks Perner, J; Provazník, J; Schrenková, J; Urbanová, V; Ribeiro, JM; Kopáček, P; Sci Rep, DOI://10.1038/srep36695 (2016)
Transgenic mouse model of IgM(+) lymphoproliferative disease mimicking Waldenström macroglobulinemia Tompkins, VS; Sompallae, R; Rosean, TR et al. Blood Cancer J, DOI://10.1038/bcj.2016.95 (2016)
Mechanism of O2 diffusion and reduction in FeFe hydrogenases Adam Kubas, Christophe Orain et al. Nature Chemistry, doi:10.1038/nchem.2592 (2016)

Variance Decomposition for Single-Subject task-based fMRI activity estimates across many sessions Javier Gonzalez-Castillo, Gang Chen, Thomas E. Nichols, Peter A. Bandettini NeuroImage, doi://10.1016/j.neuroimage.2016.10.024 (2016)
Explicit Incorporation of Hard and Soft Protein-Protein Interactions Into Models for Crowding Effects in Binary and Ternary Protein Mixtures I. Comparison of Approximate Analytical Solutions With Numerical Simulation Travis Hoppe, and Allen P. Minton J. Phys. Chem. B, DOI: 10.1021/acs.jpcb.6b07736 (2016)
Resting State Connectivity of the Human Habenula at Ultra-High Field Salvatore Torrisi, Camilla L. Nord, Nicholas L. Balderston, Jonathan P. Roiser, Christian Grillon, Monique Ernst NeuroImage, 10.1016/j.neuroimage.2016.10.034 (2016)
The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts Saini, N; Roberts, SA; Klimczak, LJ et al. PLoS Genet., DOI://10.1371/journal.pgen.1006385 (2016)
Roles of H3K27me2 and H3K27me3 Examined during Fate Specification of Embryonic Stem Cells Juan, AH; Wang, S; Ko, KD et al. Cell Rep, DOI://10.1016/j.celrep.2016.09.087 (2016)
Deriving frequency-dependent spatial patterns in MEG-derived resting state sensorimotor network: A novel multiband ICA technique Nugent, A. C., Luber, B., Carver, F. W., Robinson, S. E., Coppola, R. and Zarate, C. A. Hum. Brain Mapp., doi:10.1002/hbm.23417 (2016)

Additional Rare Variant Analysis in Parkinson's Disease Cases with and Without Known Pathogenic Mutations: Evidence for Oligogenic Inheritance Steven J. Lubbe, Valentina Escott-Price et al. Human Molecular Genetics, doi://10.1093/hmg/ddw348 (2016)
Longitudinal imaging in C9orf72 mutation carriers: Relationship to phenotype Mary Kay Floeter, Devin Bageac, Laura E. Danielian, Laura E. Braun, Bryan J. Traynor, , Justin Kwan NeuroImage: Clinical, doi://10.1016/j.nicl.2016.10.014 (2016)
Racial differences in microRNA and gene expression in hypertensive women Dluzen, DF; Noren Hooten, N; Zhang, Y et al. Sci Rep, DOI://10.1038/srep35815 (2016)
Structural Characterization of Arginine Fingers: Identification of an Arginine Finger for the Pyrophosphatase dUTPases Gergely N Nagy, Reynier Suardiaz, Anna Lopata, Oliver Ozohanics, Karoly Vekey, Bernard R. Brooks, Ibolya Leveles, Judit Toth, Beata G Vertessy, and Edina Rost JACS, doi://10.1021/jacs.6b09012 (2016)
Molecular lock regulates binding of glycine to a primitive NMDA receptor Alvin Yu, Robert Alberstein, Alecia Thomas, Austin Zimmet, Richard Grey, Mark L. Mayer, and Albert Y. Lau PNAS, doi: 10.1073/pnas.1607010113 (2016)
Sources and implications of whole-brain fMRI signals in humans Jonathan D Power, Mark Plitt, Timothy O Laumann, Alex Martin Neuroimage, doi://10.1016/j.neuroimage.2016.09.038 (2016)

Diagnosis of Parkinson's disease on the basis of clinical-genetic classification: a population-based modelling study Mike A. Nalls, Cory Y. McLean et al. Lancet Neurol., doi: 10.1016/S1474-4422(15)00178-7 (2016)
Microenvironmental Gene Expression Plasticity Among Individual Drosophila melanogaster Lin, Y; Chen, ZX; Oliver, B; Harbison, ST; G3 (Bethesda), DOI://10.1534/g3.116.035444 (2016)
A RUNX2-Mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells Shin, MH; He, Y; Marrogi, E et al. PLoS Genet., DOI://10.1371/journal.pgen.1005884 (2016)
Sp5 and Sp8 recruit β-catenin and Tcf1-Lef1 to select enhancers to activate Wnt target gene transcription Kennedy, MW; Chalamalasetty, RB; Thomas, S; Garriock, RJ; Jailwala, P; Yamaguchi, TP; Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1519994113 (2016)
Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number Lyons, JJ; Yu, X; Hughes, JD et al. Nat. Genet., DOI://10.1038/ng.3696 (2016)
SARAH Domain-Mediated MST2-RASSF Dimeric Interactions Goar Sànchez-Sanz , Bartomiej Tywoniuk , David Matallanas, David Romano, Lan K. Nguyen, Boris N. Kholodenko, Edina Rosta , Walter Kolch , Nicolae-Viorel Buchete PLoS Computational Biology, doi://10.1371/journal.pcbi.1005051 (2016)

Systems-level analysis reveals selective regulation of Aqp2 gene expression by vasopressin Sandoval, PC; Claxton, JS; Lee, JW; Saeed, F; Hoffert, JD; Knepper, MA; Sci Rep, DOI://10.1038/srep34863 (2016)
Evaluation of KIR3DL1/KIR3DS1 polymorphism in Behçet's disease Erer, B; Takeuchi, M; Ustek, D et al. Genes Immun., DOI://10.1038/gene.2016.36 (2016)
Rapid development of a DNA vaccine for Zika virus Dowd, KA; Ko, SY; Morabito, KM et al. Science, DOI://10.1126/science.aai9137 (2016)
A Modified P1 Moiety Enhances in vitro Antiviral Activity against Various Multi-Drug-Resistant HIV-1 Variants and in vitro CNS Penetration Properties of a Novel Nonpeptidic Protease Inhibitor, GRL-10413 Masayuki Amano, Pedro Miguel Salcedo-Gomez, Rui Zhao, Ravikiran S. Yedidi, Debananda Das, Haydar Bulut, Nicole S. Delino, Sheri Venkata Reddy, Arun K. Ghosh and Hiroaki Mitsuya Antimicrobial Agents and Chemotherapy, doi: 10.1128/AAC.01428-16 (2016)
Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations BH Chen, M-F Hivert et al. Diabetes, doi://10.2337/db16-0470 (2016)
On the Selective Packaging of Genomic RNA by HIV-1 Mauricio Comas-Garcia, Sean R. Davis and Alan Rein Viruses, doi://10.3390/v8090246 (2016)

Behavioral and Neural Sustained Attention Deficits in Bipolar Disorder and Familial Risk for Bipolar Disorder David Pagliaccio, Jillian Lee Wiggins, et al. Biological Psychiatry, doi://10.1016/j.biopsych.2016.09.006 (2016)
Mutations of SGO2 and CLDN14 collectively cause coincidental Perrault syndrome R Faridi, AR Rehman et al. Clinical Genetics, DOI: 10.1111/cge.12867 (2016)
CYP2A6 genetic variation alters striatal-cingulate circuits, network hubs, and executive processing in smokers Sufang Li, Yihong Yang, Ewa Hoffmann, Rachel F. Tyndale, Elliot A. Stein Biological Psychiatry, doi://10.1016/j.biopsych.2016.09.013 (2016)
Absolute binding free energies for octa-acids and guests in SAMPL5 Florentina Tofoleanu, Juyong Lee, Frank C. Pickard IV, Gerhard Kzönig, Jing Huang, Minkyung Baek, Chaok Seok, Bernard R. Brooks J. Computer-Aided Molecular Design, DOI: 10.1007/s10822-016-9965-5 (2016)
Introduction, evolution, and dissemination of influenza A viruses in exhibition swine, USA, 2009-2013 Martha I. Nelson, Karla M. Stucker, et al. J. Virology, doi: 10.1128/JVI.01457-16 (2016)
Novel genetic loci underlying human intracranial volume identified through genome-wide association Adams, HH; Hibar, DP; Chouraki, V et al. Nat. Neurosci., DOI://10.1038/nn.4398 (2016)
Differential cytokine sensitivities of STAT5-dependent enhancers rely on Stat5 autoregulation Willi, M; Yoo, KH; Wang, C; Trajanoski, Z; Hennighausen, L; Nucleic Acids Res., DOI://10.1093/nar/gkw844 (2016)
DNA methylation-based measures of biological age: meta-analysis predicting time to death Chen, BH; Marioni, RE; Colicino, E et al. Aging (Albany NY), DOI://10.18632/aging.101020 (2016)
Characterization and phosphoproteomic analysis of a human immortalized podocyte model of Fabry disease generated using CRISPR/Cas9 technology Pereira, EM; Labilloy, A; Eshbach, ML et al. Am. J. Physiol. Renal Physiol., DOI://10.1152/ajprenal.00283.2016 (2016)
Alternative Isoform Analysis of Ttc8 Expression in the Rat Pineal Gland Using a Multi-Platform Sequencing Approach Reveals Neural Regulation Hartley, SW; Mullikin, JC; Klein, DC; Park, M; , ; Coon, SL; PLoS ONE, DOI://10.1371/journal.pone.0163590 (2016)
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals Ehret, GB; Ferreira, T; Chasman, DI et al. Nat. Genet., DOI://10.1038/ng.3667 (2016)
Integrative Transcriptome Analyses of Metabolic Responses in Mice Define Pivotal LncRNA Metabolic Regulators Yang, L; Li, P; Yang, W et al. Cell Metab., DOI://10.1016/j.cmet.2016.08.019 (2016)
REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants Ioannidis, NM; Rothstein, JH; Pejaver, V et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2016.08.016 (2016)
Oncogenic Mutations Differentially Affect Bax Monomer, Dimer, and Oligomeric Pore Formation in the Membrane Mingzhen Zhang, Jie Zheng, Ruth Nussinov, Buyong Ma Scientific Reports, 10.1038/srep33340 (2016)
Association of Superoxide Dismutase 2 (SOD2) Genotype with Gray Matter Volume Shrinkage in Chronic Alcohol Users: Replication and Further Evaluation of an Addiction Gene Panel Gitik M, Srivastava V, Hodgkinson CA, Shen PH, Goldman D, Meyerhoff DJ Int. J. Neuropsychopharmacol., DOI://10.1093/ijnp/pyw033 (2016)
Daily physical activity patterns from hip- and wrist-worn accelerometers Shiroma, EJ; Schepps, MA; Harezlak, J et al. Physiol Meas, DOI://10.1088/0967-3334/37/10/1852 (2016)
DNA Transposition at Work Hickman, AB; Dyda, F; Chem. Rev., DOI://10.1021/acs.chemrev.6b00003 (2016)
Expression, purification and identification of a thermolysin-like protease, neutral protease I, from Aspergillus oryzae with the Pichia pastoris expression system Ma, X; Liu, Y; Li, Q et al. Protein Expr. Purif., DOI://10.1016/j.pep.2016.08.008 (2016)

The African diaspora: history, adaptation and health Rotimi CN, Tekola-Ayele F, Baker JL, Shriner D Curr. Opin. Genet. Dev., DOI://10.1016/j.gde.2016.08.005 (2016)
3D-printed head models for navigated non-invasive brain stimulation Dayan, E; Thompson, RM; Buch, ER; Cohen, LG; Clin Neurophysiol, DOI://10.1016/j.clinph.2016.08.011 (2016)
Distinct fMRI Responses to Self-Induced versus Stimulus Motion during Free Viewing in the Macaque Russ, BE; Kaneko, T; Saleem, KS; Berman, RA; Leopold, DA; J. Neurosci., DOI://10.1523/JNEUROSCI.1152-16.2016 (2016)
Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder Hou, L; Bergen, SE; Akula, N et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddw181 (2016)
A genome-wide association study in multiple system atrophy Sailer, A; Scholz, SW; Nalls, MA et al. Neurology, DOI://10.1212/WNL.0000000000003221 (2016)
Diverse Human Skin Fungal Communities in Children Converge in Adulthood Jo, JH; Deming, C; Kennedy, EA et al. J. Invest. Dermatol., DOI://10.1016/j.jid.2016.05.130 (2016)

An efficient protocol for obtaining accurate hydration free energies using quantum chemistry and reweighting from molecular dynamics simulations Frank C. Pickard, Gerhard Koenig, Andrew C. Simmonett, Yihan Shao, Bernard R. Brooks Bioorganic & Medicinal Chemistry, doi://10.1016/j.bmc.2016.08.031 (2016)
Skin microbiome before development of atopic dermatitis: Early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year s: Kennedy EA, Connolly J, O'B Hourihane J, Fallon PG, McLean WI, Murray D, Jo J-H, Segre JA, Kong HH, Irvine AD J. Allergy and Clinical Immunology , doi: 10.1016/j.jaci.2016.07.029 (2016)
Effects of Gene Dose, Chromatin, and Network Topology on Expression in Drosophila melanogaster Hangnoh Lee, Dong-Yeon Cho, Cale Whitworth, Robert Eisman, Melissa Phelps, John Roote, Thomas Kaufman, Kevin Cook, Steven Russell, Teresa Przytycka, Brian Oliver PLoS Genetics, doi://10.1371/journal.pgen.1006295 (2016)
A Model for Transposition of the Colistin Resistance Gene mcr-1 by ISApl1 Snesrud, E; He, S; Chandler, M et al. Antimicrob. Agents Chemother., DOI://10.1128/AAC.01457-16 (2016)
Transferability of genome-wide associated loci for asthma in African Americans Faruque, MU; Chen, G; Doumatey, AP et al. J Asthma, DOI://10.1080/02770903.2016.1188941 (2016)
Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease Zhou, Q; Yu, X; Demirkaya, E et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1612594113 (2016)

GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium Matteini, AM; Tanaka, T; Karasik, D et al. Aging Cell, DOI://10.1111/acel.12468 (2016)
Quantifying antiepileptic drug effects using intrinsic excitability measures Christian Meisel, Dietmar Plenz, Andreas Schulze-Bonhage, Heinz Reichmann Epilepsia, DOI: 10.1111/epi.13517 (2016)
Genetic causes of moderate to severe hearing loss point to modifiers S. Naz, A. Imtiaz et al. Clinical Genetics, DOI: 10.1111/cge.12856 (2016)
Bi-allelic Truncating Mutations in CEP78, Encoding Centrosomal Protein 78, Cause Cone-Rod Degeneration with Sensorineural Hearing Loss Prasanthi Namburi, Rinki Ratnapriya et al. Am. J. Hum. Genet., doi://10.1016/j.ajhg.2016.07.010 (2016)
Structural basis of kainate subtype glutamate receptor desensitization Joel R. Meyerson, Sagar Chittori, Alan Merk, Prashant Rao, Tae Hee Han, Mihaela Serpe, Mark L. Mayer & Sriram Subramaniam Nature, doi:10.1038/nature19352 (2016)
Probing the Action of Chemical Denaturant on an Intrinsically Disordered Protein by Simulation and Experiment Wenwei Zheng, Alessandro Borgia, Karin Buholzer, Alexander Grishaev, Benjamin Schuler, and Robert B. Best JACS, DOI: 10.1021/jacs.6b05443 (2016)

Consistent View of Polypeptide Chain Expansion in Chemical Denaturants from Multiple Experimental Methods A Borgia, W Zheng, et al. JACS, DOI: 10.1021/jacs.6b05917 (2016)
HMGN proteins modulate chromatin regulatory sites and gene expression during activation of naïve B cells Zhang, S; Zhu, I; Deng, T et al. Nucleic Acids Res., DOI://10.1093/nar/gkw323 (2016)
Analysis of Ly49 gene transcripts in mature NK cells supports a role for the Pro1 element in gene activation, not gene expression McCullen MV, Li H, Cam M, Sen SK, McVicar DW, Anderson SK Genes Immun., DOI://10.1038/gene.2016.31 (2016)
Calculating distribution coefficients based on multi-scale free energy simulations: an evaluation of MM and QM/MM explicit solvent simulations of water-cyclohexane transfer in the SAMPL5 challenge König, G; Pickard, FC; Huang, J et al. J. Comput. Aided Mol. Des., DOI://10.1007/s10822-016-9936-x (2016)
Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans Evans, DS; Avery, CL; Nalls, MA et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddw284 (2016)
Altered Human Memory Modification in the Presence of Normal Consolidation Censor N, Buch ER, Nader K, Cohen LG Cereb. Cortex, DOI://10.1093/cercor/bhv180 (2016)
Three-Dimensional Digital Template Atlas of the Macaque Brain Reveley, C; Gruslys, A; Ye, FQ et al. Cereb. Cortex, DOI://10.1093/cercor/bhw248 (2016)
Pleiotropic Analysis of Lung Cancer and Blood Triglycerides Zuber, V; Marconett, CN; Shi, J et al. J. Natl. Cancer Inst., DOI://10.1093/jnci/djw167 (2016)
Early-Childhood Social Reticence Predicts Brain Function in Preadolescent Youths During Distinct Forms of Peer Evaluation Jarcho JM, Davis MM, Shechner T, Degnan KA, Henderson HA, Stoddard J, Fox NA, Leibenluft E, Pine DS, Nelson EE Psychol Sci., doi: 10.1177/0956797616638319 (2016)
Global diversity in the TAS2R38 bitter taste receptor: revisiting a classic evolutionary PROPosal Risso DS, Mezzavilla M et al. Sci Rep., doi: 10.1038/srep25506 (2016)
A Deep Insight into the Sialome of Male and Female Aedes aegypti Mosquitoes Ribeiro JM, Martin-Martin I, Arcà B, Calvo E PLoS One., doi: 10.1371/journal.pone.0151400 (2016)
Noise Estimation and Reduction in Multispectral Magnetic Resonance Images Bouhrara M, Bonny JM, Ashinsky B, Maring M, Spencer R IEEE Trans Med Imaging, DOI://10.1109/TMI.2016.2601243 (2016)
Amygdala response to explicit sad face stimuli at baseline predicts antidepressant treatment response to scopolamine in major depressive disorder Szczepanik, J; Nugent, AC; Drevets, WC; Khanna, A; Zarate, CA; Furey, ML; Psychiatry Res, DOI://10.1016/j.pscychresns.2016.06.005 (2016)
Structure-Based Screening of Uncharted Chemical Space for Atypical Adenosine Receptor Agonists Rodríguez, D; Chakraborty, S; Warnick, E et al. ACS Chem. Biol., DOI://10.1021/acschembio.6b00357 (2016)
Internal Proteins of the Procapsid and Mature Capsids of Herpes Simplex Virus 1 Mapped by Bubblegram Imaging Wu W, Newcomb WW, Cheng N, Aksyuk A, Winkler DC, Steven AC J Virol. , doi: 10.1128/JVI.03224-15 (2016)
A Deep Insight into the Sialome of Rhodnius neglectus, a Vector of Chagas Disease Santiago PB, Assumpcao TC et al. PLoS Negl Trop Dis., doi: 10.1371/journal.pntd.0004581 (2016)
A Class of Diacylglycerol Acyltransferase 1 Inhibitors Identified by a Combination of Phenotypic High-throughput Screening, Genomics, and Genetics Tschapalda K, Zhang YQ et al. EBioMedicine., doi: 10.1016/j.ebiom.2016.04.014 (2016)
Age-related differences in the neural correlates of trial-to-trial variations of reaction time Adleman NE, Chen G, Reynolds RC, Frackman A, Razdan V, Weissman DH, Pine DS, Leibenluft E Dev Cogn Neurosci., doi: 10.1016/j.dcn.2016.05.001. (2016)

Copy Number Variation in TAS2R Bitter Taste Receptor Genes: Structure, Origin, and Population Genetics Roudnitzky N, Risso D, Drayna D, Behrens M, Meyerhof W, Wooding SP Chem Senses., DOI: 10.1093/chemse/bjw067 (2016)
Linking Genes and Brain Development of Honeybee Workers: A Whole-Transcriptome Approach Vleurinck C, Raub S, Sturgill D, Oliver B, Beye M PLoS One, doi: 10.1371/journal.pone.0157980 (2016)
Preliminary differences in resting state MEG functional connectivity pre- and post-ketamine in major depressive disorder Nugent AC, Robinson SE, Coppola R, Zarate CA Psychiatry Res, DOI://10.1016/j.pscychresns.2016.06.006 (2016)
Global intron retention mediated gene regulation during CD4+ T cell activation Ni, T; Yang, W; Han, M et al. Nucleic Acids Res., DOI://10.1093/nar/gkw591 (2016)
Estimating relative risk of a log-transformed exposure measured in pools Mitchell EM, Plowden TC, Schisterman EF Stat Med, DOI://10.1002/sim.7075 (2016)
An interactive web-based application for Comprehensive Analysis of RNAi-screen Data Dutta B, Azhir A et al. Nature Communications, doi: 10.1038/ncomms10578. (2016)

Neural Correlates of Irritability in Disruptive Mood Dysregulation and Bipolar Disorders Wiggins JL, Brotman MA, Adleman NE, Kim P, Oakes AH, Reynolds RC, Chen G, Pine DS, Leibenluft E Am J Psychiatry., doi: 10.1176/appi.ajp.2015.15060833 (2016)
Genomic insights into the Ixodes scapularis tick vector of Lyme disease Gulia-Nuss M, Nuss AB et al. Nat Commun. , doi: 10.1038/ncomms10507 (2016)
Prefrontal GABA Levels Measured With Magnetic Resonance Spectroscopy in Patients With Psychosis and Unaffected Siblings Marenco S, Meyer C, Kuo S, van der Veen JW, Shen J, DeJong K, Barnett AS, Apud JA, Dickinson D, Weinberger DR, Berman KF Am J Psychiatry, doi: 10.1176/appi.ajp.2015 (2016)
Rare copy number variants implicated in posterior urethral valves Boghossian NS, Sicko RJ et al Am J Med Genet A., doi: 10.1002/ajmg.a.37493 (2016)
Computational evaluation of exome sequence data using human and model organism phenotypes improves diagnostic efficiency Bone WP, Washington NL et al. Genet Med, doi: 10.1038/gim.2015.137 (2016)
TCRβ repertoire of CD4+ and CD8+ T cells is distinct in richness, distribution, and CDR3 amino acid composition Li HM, Hiroi T, Zhang Y, Shi A, Chen G, De S, Metter EJ, Wood WH rd, Sharov A, Milner JD, Becker KG, Zhan M, Weng NP J Leukoc Biol., doi: 10.1189/jlb.6A0215-071RR (2016)

Neural correlates of masked and unmasked face emotion processing in youth with severe mood dysregulation Tseng WL, Thomas LA, Harkins E, Pine DS, Leibenluft E, Brotman MA Soc Cogn Affect Neurosci, doi: 10.1093/scan/nsv087 (2016)
Evolving specificity of tRNA 3-methyl-cytidine-32 (m3C32) modification: a subset of tRNAsSer requires N6-isopentenylation of A37 Arimbasseri, AG; Iben, J; Wei, FY et al. RNA, DOI://10.1261/rna.056259.116 (2016)
Phosphorylation of residues inside the SNARE complex suppresses secretory vesicle fusion Malmersjo, S; Di Palma, S; Diao, J et al. EMBO J., DOI://10.15252/embj.201694071 (2016)
Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration Yu Chen, Grazyna Palczewska, et al. Sci Signal. , doi: 10.1126/scisignal.aag0245 (2016)
A simple but useful way to assess fMRI scan qualities Jonathan D. Power NeuroImage, doi:10.1016/j.neuroimage.2016.08.009 (2016)
Conformational dynamics of cancer-associated MyD88-TIR domain mutant L252P (L265P) allosterically tilts the landscape toward homo-dimerization Chendi Zhan, Ruxi Qi, Guanghong Wei, Emine Guven-Maiorov, Ruth Nussinov and Buyong Ma Protein Engineering, Design and Selection, doi: 10.1093/protein/gzw033 (2016)

Altered striatal intrinsic functional connectivity in pediatric anxiety Dorfman J, Benson B, Farber M, Pine D, Ernst M Neuropsychologia, doi: 10.1016/j.neuropsychologia.2016.03.019 (2016)
Next-generation sequencing reveals substantial genetic contribution to dementia with Lewy bodies Geiger, JT; Ding, J; Crain, B et al. Neurobiol. Dis., DOI://10.1016/j.nbd.2016.06.004 (2016)
Commonalities in Development of Pure Breeds and Population Isolates Revealed in the Genome of the Sardinian Fonni's Dog Dreger, DL; Davis, BW; Cocco, R et al. Genetics, DOI://10.1534/genetics.116.192427 (2016)
An Enantiomer of an Oral Small-Molecule TSH Receptor Agonist Exhibits Improved Pharmacologic Properties Neumann, S; Padia, U; Cullen, MJ et al. Front Endocrinol (Lausanne), DOI://10.3389/fendo.2016.00105 (2016)
PreSMA stimulation changes task-free functional connectivity in the fronto-basal-ganglia that correlates with response inhibition efficiency Xu, B; Sandrini, M; Wang, WT et al. Hum Brain Mapp, DOI://10.1002/hbm.23236 (2016)
Coffee Drinking Is Widespread in the United States but Usual Intake Varies by Key Demographic and Lifestyle Factors Erikka Loftfield, Neal D Freedman, Kevin W Dodd, Emily Vogtmann, Qian Xiao, Rashmi Sinha, and Barry I Graubard J. Nutrition, doi: 10.3945/jn.116.233940 (2016)

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals John D. Eicher, Nathalie Chami, et al. Am. J. Hum. Genet. , doi://10.1016/j.ajhg.2016.05.005 . (2016)
AptaTRACE Elucidates RNA Sequence-Structure Motifs from Selection Trends in HT-SELEX Experiments Phuong Dao, Jan Hoinka, Mayumi Takahashi, Jiehua Zhou, Michelle Ho, Yijie Wang, Fabrizio Costa, John J. Rossi, Rolf Backofen, John Burnett, Teresa M. Przytycka Cell Systems, doi:10.1016/j.cels.2016.07.003 (2016)
C-5-Modified Tetrahydropyrano-Tetrahydofuran-Derived Protease Inhibitors (PIs) Exert Potent Inhibition of the Replication of HIV-1 Variants Highly Resistant to Various PIs, including Darunavir Manabu Aoki, Hironori Hayashi, Ravikiran S. Yedidi, Cuthbert D. Martyr, Yuki Takamatsu, Hiromi Aoki-Ogat, Teruya Nakamura, Hirotomo Nakata, Debananda Das, Yuriko Yamagata, Arun K. Ghosh and Hiroaki Mitsuya J. Virology, doi: 10.1128/JVI.01829-15 (2016)
SMAC mimetic birinapant plus radiation eradicates human head and neck cancers with genomic amplifications of cell death genes FADD and BIRC2 Danielle F Eytan, Grace E Snow, Sophie Carlson, Adeeb Derakhshan, Anthony Saleh, Stephen Schiltz, Hui Cheng, Suresh Mohan, Shaleeka Cornelius, Jamie F Coupar, Anastasia L. Sowers, Lidia Hernandez, James B. Mitchell, Christina M. Annunziata, Zhong Chen, Carter Van Waes Cancer Research, DOI: 10.1158/0008-5472.CAN-15-3317 (2016)
Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies. Demirkan A, Lahti J et al Psychol Med, doi: 10.1017/S0033291715002081 (2016)
Modeling RNA topological structures using small angle X-ray scattering Yuba R. Bhandari, Wei Jiang, Eric A. Stahlberg, Jason R. Stagno, Yun-Xing Wang Methods, doi:10.1016/j.ymeth.2016.04.015 (2016)

Comparing biomarkers as trial level general surrogates Erin E Gabriel, Michael J. Daniels, M. Elizabeth Halloran Biometrics, DOI: 10.1111/biom.12513 (2016)
Diffusive Dynamics of Contact Formation in Disordered Polypeptides Gül H. Zerze, Jeetain Mittal, and Robert B. Best Phys. Rev. Lett., doi://10.1103/PhysRevLett.116.068102 (2016)
Genome-wide cooperation by HAT Gcn5, remodeler SWI/SNF, and chaperone Ydj1 in promoter nucleosome eviction and transcriptional activation Hongfang Qiu, Razvan V. Chereji, Cuihua Hu, Hope A. Cole, Yashpal Rawal, David J. Clark, and Alan G. Hinnebusch Genome Research, doi: 10.1101/gr.196337.115 (2016)
The evolutionary turnover of recombination hot spots contributes to speciation in mice Fatima Smagulova, Kevin Brick, Yongmei Pu, R. Daniel Camerini-Otero, and Galina V. Petukhova Genes. Dev. , doi: 10.1101/gad.270009.115 (2016)
Origins of the 2009 H1N1 influenza pandemic in swine in Mexico Ignacio Mena, Martha I Nelson, et al. eLife, doi://10.7554/eLife.16777 (2016)
A Powerful Procedure for Pathway-Based Meta-analysis Using Summary Statistics Identifies 43 Pathways Associated with Type II Diabetes in European Populations Han Zhang, William Wheeler, Paula L. Hyland, Yifan Yang, Jianxin Shi, Nilanjan Chatterjee, and Kai Yu PLoS Genetics, doi: 10.1371/journal.pgen.1006122 (2016)

Evaluation of multi-echo ICA denoising for task based fMRI studies: Block designs, rapid event-related designs, and cardiac-gated fMRI Javier Gonzalez-Castillo, Puja Panwar, Laura C. Buchanan, Cesar Caballero-Gaudes, Daniel A. Handwerker, David C. Jangraw, Valentinos Zachariou, Souheil Inati, Vinai Roopchansingh, John A. Derbyshire, Peter A. Bandettini NeuroImage, doi:10.1016/j.neuroimage.2016.07.049 (2016)
Rare Variants Analysis of Cutaneous Malignant Melanoma Genes in Parkinson's Disease S.J. Lubbe, V. Escott-Price et al, the Melanoma Meta-Analysis Consortium, the International Parkinson's Disease Genomics Consortium Neurobiology of Aging, doi:10.1016/j.neurobiolaging.2016.07.013 (2016)
Crystal structure of the antigen-binding fragment of a monoclonal antibody specific for the multidrug-resistance-linked ABC transporter human P-glycoprotein Lothar Esser, Suneet Shukla, Fei Zhou, Suresh V. Ambudkar and Di Xia Acta Cryst. F, doi:10.1107/S2053230X16009778 (2016)
Certified DNA Reference Materials to Compare HER2 Gene Amplification Measurements Using Next-Generation Sequencing Methods Chih-Jian Lih, Han Si et al. J. Mol. Diag. , doi:10.1016/j.jmoldx.2016.05.008 (2016)
Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses Joyce, MG; Wheatley, AK; Thomas, PV et al. Cell, DOI://10.1016/j.cell.2016.06.043 (2016)
Characterizing human lung tissue microbiota and its relationship to epidemiological and clinical features Yu, G; Gail, MH; Consonni, D et al. Genome Biol., DOI://10.1186/s13059-016-1021-1 (2016)

Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies Joshi, AD; Andersson, C; Buch, S et al. Gastroenterology, DOI://10.1053/j.gastro.2016.04.007 (2016)
Polybrominated Diphenyl Ethers: Structure Determination and Trends in Antibacterial Activity Liu, H; Lohith, K; Rosario, M et al. J. Nat. Prod., DOI://10.1021/acs.jnatprod.6b00229 (2016)
Association of Maternal Prepregnancy Dyslipidemia With Adult Offspring Dyslipidemia in Excess of Anthropometric, Lifestyle, and Genetic Factors in the Framingham Heart Study Mendelson MM, Lyass A, O'Donnell CJ, D'Agostino RB, Levy D JAMA Cardiol, DOI://10.1001/jamacardio.2015.0304 (2016)
Comparison of Sedentary Estimates between activPAL and Hip- and Wrist-Worn ActiGraph Koster, A; Shiroma, EJ; Caserotti, P et al. Med Sci Sports Exerc, DOI://10.1249/MSS.0000000000000924 (2016)
Design strategies to address the effect of hydrophobic epitope on stability and in vitro assembly of modular virus-like particle Tekewe, A; Connors, NK; Middelberg, AP; Lua, LH; Protein Sci., DOI://10.1002/pro.2953 (2016)
South (S)- and North (N)-Methanocarba-7-Deazaadenosine Analogues as Inhibitors of Human Adenosine Kinase Kiran S. Toti, Danielle Osborne, Antonella Ciancetta, Detlev Boison, and Kenneth A. Jacobson J. Med. Chem. , DOI: 10.1021/acs.jmedchem.6b00689 (2016)

Change in Epigenome-Wide DNA Methylation Over 9 Years and Subsequent Mortality: Results From the InCHIANTI Study Moore, AZ; Hernandez, DG; Tanaka, T et al. J. Gerontol. A Biol. Sci. Med. Sci., DOI://10.1093/gerona/glv118 (2016)
A Cascade of Wnt, Eda, and Shh Signaling Is Essential for Touch Dome Merkel Cell Development Xiao, Y; Thoresen, DT; Miao, L et al. PLoS Genet., DOI://10.1371/journal.pgen.1006150 (2016)
Complete Genome Sequence of a Klebsiella pneumoniae Strain Carrying blaNDM-1 on a Multidrug Resistance Plasmid Conlan S, Lau AF, , Palmore TN, Frank KM, Segre JA Genome Announc, DOI://10.1128/genomeA.00664-16 (2016)
Computational study of the inhibitory mechanism of the kinase CDK5 hyperactivity by peptide p5 and derivation of a pharmacophore A. Cardone, M. Brady, R. Sriram, H. C. Pant, S. A. Hassan J. Computer-Aided Molecular Design, DOI: 10.1007/s10822-016-9922-3 (2016)
A Comparison Study of Fixed and Mixed Effect Models for Gene Level Association Studies of Complex Traits Ruzong Fan, Chi-yang Chiu, Jeesun Jung, Daniel E. Weeks, Alexander F. Wilson, Joan E. Bailey-Wilson, Christopher I. Amos, Zhen Chen, James L. Mills and Momiao Xiong Genetic Epidemiology, DOI: 10.1002/gepi.21984 (2016)
Mutational Spectrum of MYO15A and the Molecular Mechanisms of DFNB3 Human Deafness Atteeq U. Rehman, Jonathan E. Bird, Rabia Faridi, Mohsin Shahzad, Sujay Shah, Kwanghyuk Lee, Shaheen N. Khan, Ayesha Imtiaz, Zubair M. Ahmed, Saima Riazuddin, Regie Lyn P. Santos- Cortez, Wasim Ahmad, Suzanne M. Leal, Sheikh Riazuddin, Thomas B. Friedman Human Mutation, DOI: 10.1002/humu.23042 (2016)

Transmission-blocking activity is determined by transmission-reducing activity and number of control oocysts in Plasmodium falciparum standard membrane-feeding assay Kazutoyo Miura, Bruce J. Swihart, Bingbing Deng, Luwen Zhou, Thao P. Pham, Ababacar Diouf, Timothy Burton, Michael P. Fay, Carole A. Long Vaccine, doi:10.1016/j.vaccine.2016.06.066 (2016)
Tyrosine-sulfated V2 peptides inhibit HIV-1 infection via coreceptor mimicry Raffaello Cimbro, Francis C. Peterson, Qingbo Liu, Christina Guzzo, Peng Zhang, Huiyi Miao, Donald Van Ryk, Xavier Ambroggio, Darrell E. Hurt, Luca De Gioia, Brian F. Volkman, Michael A. Dolan, Paolo Lusso EBioMedicine, doi:10.1016/j.ebiom.2016.06.037 (2016)
Defining the neuroanatomic basis of motor coordination in children and its relationship with symptoms of attention-deficit/hyperactivity disorder Shaw, P; Weingart, D; Bonner, T et al. Psychol Med, DOI://10.1017/S0033291716000660 (2016)
Common Variation in the DOPA Decarboxylase (DDC) Gene and Human Striatal DDC Activity In Vivo Eisenberg, DP; Kohn, PD; Hegarty, CE et al. Neuropsychopharmacology, DOI://10.1038/npp.2016.31 (2016)
Improving Motor Corticothalamic Communication After Stroke Using Real-Time fMRI Connectivity-Based Neurofeedback Liew, SL; Rana, M; Cornelsen, S et al. Neurorehabil Neural Repair, DOI://10.1177/1545968315619699 (2016)
Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits Chami, N; Chen, MH; Slater, AJ et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2016.05.007 (2016)

Pathogenic role of B-cell receptor signaling and canonical NF-κB activation in mantle cell lymphoma Saba, NS; Liu, D; Herman, SE et al. Blood, DOI://10.1182/blood-2015-11-681460 (2016)
Chromatin Landscape of the IRF Genes and Role of the Epigenetic Reader BRD4 Bachu, M; Dey, A; Ozato, K; J. Interferon Cytokine Res., DOI://10.1089/jir.2015.0179 (2016)
Fine-tuning of CD8(+) T-cell effector functions by targeting the 2B4-CD48 interaction Lissina, A; Ambrozak, DR; Boswell, KL et al. Immunol. Cell Biol., DOI://10.1038/icb.2016.17 (2016)
Dataset of Arabidopsis plants that overexpress FT driven by a meristem-specific KNAT1 promoter Duplat-Bermúdez, L; Ruiz-Medrano, R; Landsman, D; Mariño-Ramírez, L; Xoconostle-Cázares, B; Data Brief, DOI://10.1016/j.dib.2016.06.002 (2016)
The genetic regulatory signature of type 2 diabetes in human skeletal muscle Scott, LJ; Erdos, MR; Huyghe, JR et al. Nat Commun, DOI://10.1038/ncomms11764 (2016)
Plasmid Dynamics in KPC-Positive Klebsiella pneumoniae during Long-Term Patient Colonization Conlan, S; Park, M; Deming, C et al. MBio, DOI://10.1128/mBio.00742-16 (2016)

Structure-Based Design of 3-(4-Aryl-1H-1,2,3-triazol-1-yl)-Biphenyl Derivatives as P2Y14 Receptor Antagonists Anna Junker, Ramachandran Balasubramanian, Antonella Ciancetta, Elisa Uliassi, Evgeny Kiselev, Chiara Martiriggiano, Kevin Trujillo, Giorgi Mtchedlidze, Leah Birdwell, Kyle A. Brown, T. Kendall Harden, and Kenneth A. Jacobson J. Med. Chem. , DOI: 10.1021/acs.jmedchem.6b00044 (2016)
Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases Salman M. Tajuddin, Ursula M. Schick et al. Am. J. Hum. Genet., doi:10.1016/j.ajhg.2016.05.003 (2016)
Coarse Master Equations for Binding Kinetics of Amyloid Peptide Dimers Cathal T. Leahy, Ronan D. Murphy, Gerhard Hummer, Edina Rosta, and Nicolae-Viorel Buchete J. Phys. Chem. Lett., DOI: 10.1021/acs.jpclett.6b00518 (2016)
Recruitment of Rod Photoreceptors from Short-Wavelength-Sensitive Cones during the Evolution of Nocturnal Vision in Mammals Jung-Woong Kim, Hyun-Jin Yang, Adam Phillip Oel, Matthew John Brooks, Li Jia, David Charles Plachetzki, Wei Li, William Ted Allison, Anand Swaroop Developmental Cell, doi:10.1016/j.devcel.2016.05.023 (2016)
Enhanced exo-inulinase activity and stability by fusion of an inulin-binding module Shun-Hua Zhou, Yuan Liu, Yu-Juan Zhao, Zhe Chi, Zhen-Ming Chi, Guang-Lei Liu Applied Microbiology and Biotechnology, doi:10.1007/s00253-016-7587-4 (2016)
Ring Catalog: A resource for designing self-assembling RNA nanostructures Parlea, L; Bindewald, E; Sharan, R et al. Methods, DOI://10.1016/j.ymeth.2016.04.016 (2016)

Decreased subcortical volumes in alcohol dependent individuals: effect of polysubstance use disorder Grodin EN, Momenan R Addict Biol, DOI://10.1111/adb.12421 (2016)
Compressed Sensing Electron Tomography for Determining Biological Structure Matthew D. Guay, Wojciech Czaja, Maria A. Aronova & Richard D. Leapman Nature, doi:10.1038/srep27614 (2016)
Next generation sequencing technology and genomewide data analysis: Perspectives for retinal research Vijender Chaitankar, Gokhan Karakulah, Rinki Ratnapriya, Felipe O. Giuste, Matthew J. Brooks, Anand Swaroop Progress in Retinal and Eye Research, doi:10.1016/j.preteyeres.2016.06.001 (2016)
Taz1-Shelterin Promotes Facultative Heterochromatin Assembly at Chromosome-Internal Sites Containing Late Replication Origins Zofall M, Smith DR, Mizuguchi T, Dhakshnamoorthy J, Grewal SI Mol. Cell, DOI://10.1016/j.molcel.2016.04.034 (2016)
The homeoprotein DLX3 and tumor suppressor p53 co-regulate cell cycle progression and squamous tumor growth Palazzo, E; Kellett, M; Cataisson, C et al. Oncogene, DOI://10.1038/onc.2015.380 (2016)
Impact of Type 2 Diabetes on Impaired Kidney Function in Sub-Saharan African Populations Adebamowo, SN; Adeyemo, AA; Tekola-Ayele, F et al. Front Endocrinol (Lausanne), DOI://10.3389/fendo.2016.00050 (2016)

Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8 Soto, C; Ofek, G; Joyce, MG et al. PLoS ONE, DOI://10.1371/journal.pone.0157409 (2016)
Mapping of Ebolavirus Neutralization by Monoclonal Antibodies in the ZMapp Cocktail Using Cryo-Electron Tomography and Studies of Cellular Entry Erin E. H. Tran, Elizabeth A. Nelson, Pranay Bonagiri, James A. Simmons, Charles J. Shoemaker, Connie S . Schmaljohn, Gary P. Kobinger, Larry Zeitlin, Sriram Subramaniam, and Judith M. White J. Virol., doi:10.1128/JVI.00406-16 (2016)
Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response M L Nickerson, N Witte, K M Im, S Turan, C Owens, K Misner, S X Tsang, Z Cai, S Wu, M Dean, J C Costello and D Theodorescu Oncogene, doi: 10.1038/onc.2016.172 (2016)
Regulation of normal B-cell differentiation and malignant B-cell survival by OCT2 Hodson, DJ; Shaffer, AL; Xiao, W et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1600557113 (2016)
A replicator-specific binding protein essential for site-specific initiation of DNA replication in mammalian cells Zhang, Y; Huang, L; Fu, H et al. Nat Commun, DOI://10.1038/ncomms11748 (2016)
Decreased Expression of Retinoid X Receptors During Human and Azoxymethane-induced Colorectal Carcinogenesis in the Rat Hao, X; Xiao, H; Ju, J; Hewitt, SM; Morse, HC; Anticancer Res., 1791-7530 (2016)

H19ICR mediated transcriptional silencing does not require target promoter methylation Gebert C, Rong Q, Jeong S, Iben J, Pfeifer K Biochem. Biophys. Res. Commun., DOI://10.1016/j.bbrc.2016.05.042 (2016)
Chemoreception and neuroplasticity in respiratory circuits William H. Barnett, Ana P. Abdala, Julian F.R. Paton, Ilya A. Rybak, Daniel B. Zoccal, Yaroslav I. Molkov Experimental Neurology, doi:10.1016/j.expneurol.2016.05.036 (2016)
A novel complete-case analysis to determine statistical significance between treatments in an intention-to-treat population of randomized clinical trials involving missing data Wei Liu, Jinhui Ding Stat. Methods in Med. Res. , doi: 10.1177/0962280216651307 (2016)
Urinary Metabolite Risk Biomarkers of Lung Cancer: A Prospective Cohort Study Haznadar, M; Cai, Q; Krausz, KW et al. Cancer Epidemiol. Biomarkers Prev., DOI://10.1158/1055-9965.EPI-15-1191 (2016)
Prenatal immune programming of the sex-dependent risk for major depression Gilman, SE; Cherkerzian, S; Buka, SL; Hahn, J; Hornig, M; Goldstein, JM; Transl Psychiatry, DOI://10.1038/tp.2016.91 (2016)
Polycomb Ezh2 controls the fate of GABAergic neurons in the embryonic cerebellum Feng, X; Juan, AH; Wang, HA; Ko, KD; Zare, H; Sartorelli, V; Development, DOI://10.1242/dev.132902 (2016)
Transcriptomic analysis of Arabidopsis overexpressing flowering locus T driven by a meristem-specific promoter that induces early flowering Duplat-Bermúdez, L; Ruiz-Medrano, R; Landsman, D; Mariño-Ramírez, L; Xoconostle-Cázares, B; Gene, DOI://10.1016/j.gene.2016.04.060 (2016)
Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery Alan Merk , Alberto Bartesaghi , Soojay Banerjee , Veronica Falconieri , Prashant Rao , Mindy I. Davis , Rajan Pragani , Matthew B. Boxer , Lesley A. Earl , Jacqueline L.S. Milne , Sriram Subramaniam Cell, doi://10.1016/j.cell.2016.05.040 show (2016)
Robertsonian translocations modify genomic distribution of γH2AFX and H3.3 in mouse germ cells Fayer S, Yu Q, Kim J, Moussette S, Camerini-Otero RD, Naumova AK Mamm. Genome, DOI://10.1007/s00335-016-9630-2 (2016)
Structural Basis for the Failure of the C1 Domain of Ras Guanine Nucleotide Releasing Protein 2 (RasGRP2) to Bind Phorbol Ester with High Affinity Czikora, A; Lundberg, DJ; Abramovitz, A et al. J. Biol. Chem., DOI://10.1074/jbc.M116.725333 (2016)
Genome-wide association study identifies 74 loci associated with educational attainment Okbay, A; Beauchamp, JP; Fontana, MA et al. Nature, DOI://10.1038/nature17671 (2016)
Proinflammatory and lipid biomarkers mediate metabolically healthy obesity: A proteomics study Doumatey AP, Zhou J, Zhou M, Prieto D, Rotimi CN, Adeyemo A Obesity (Silver Spring), DOI://10.1002/oby.21482 (2016)
Encoding of Touch Intensity But Not Pleasantness in Human Primary Somatosensory Cortex Case, LK; Laubacher, CM; Olausson, H; Wang, B; Spagnolo, PA; Bushnell, MC; J. Neurosci., DOI://10.1523/JNEUROSCI.1130-15.2016 (2016)
Trajectories of microsecond molecular dynamics simulations of nucleosomes and nucleosome core particles Alexey K. Shaytan, Grigoriy A. Armeev, Alexander Goncearenco, Victor B. Zhurkin, David Landsman, Anna R. Panchenko Data in Brief, doi:10.1016/j.dib.2016.04.073 (2016)
A Transcriptionally Inactive ATF2 Variant Drives Melanomagenesis Giuseppina Claps, Yann Cheli, Tongwu Zhang, Marzia Scortegagna, Eric Lau, Hyungsoo Kim, Jianfei Qi, Jian-Liang Li, Brian James, Andreas Dzung, Mitchell P. Levesque, Reinhard Dummer, Nicholas K. Hayward, Marcus Bosenberg, Kevin M. Brown, Ze'ev A. Ronai Cell Reports, doi:10.1016/j.celrep.2016.04.072 (2016)
Untangling the relatedness among correlations, part I: Nonparametric approaches to inter-subject correlation analysis at the group level Gang Chen, Yong-Wook Shin, Paul A. Taylor, Daniel Glen, Richard C. Reynolds, Robert B. Israel, Robert W. Cox NeuroImage, doi:10.1016/j.neuroimage.2016.05.023 (2016)
Confidence assignment for mass spectrometry based peptide identifications via the extreme value distribution Gelio Alves and Yi-Kuo Yu Bioinformatics, doi: 10.1093/bioinformatics/btw22 (2016)
A single endoplasmic reticulum aminopeptidase-1 protein allotype is a strong risk factor for Behçet's disease in HLA-B*51 carriers. Takeuchi, M; Ombrello, MJ; Kirino, Y et al. Ann. Rheum. Dis., DOI://10.1136/annrheumdis-2015-209059 (2016)

Ancient Human Migration after Out-of-Africa Shriner D, Tekola-Ayele F, Adeyemo A, Rotimi CN Sci Rep, DOI://10.1038/srep26565 (2016)
Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes Stoehr, A; Yang, Y; Patel, S et al. Cardiovasc. Res., DOI://10.1093/cvr/cvw081 (2016)
Comprehensive Database of Human E3 Ubiquitin Ligases: Application to Aquaporin-2 Regulation Barbara Medvar, Viswanathan Raghuram, Trairak Pisitkun, Abhijit Sarkar, Mark A. Knepper Physiological Genomics, DOI: 10.1152/physiolgenomics.00031.2016 (2016)
Identification of modes of interactions between 9-aminoacridine hydrochloride hydrate and serum proteins by low and high resolution spectroscopy and molecular modeling Piyali Mitra, Uttam Pal, Nakul Chandra Maiti, Anirban Ghosh, Anirban Bhunia and Samita Basu Roy. Soc. Chem. , DOI: 10.1039/C6RA04140J (2016)
OptSSeq: High-throughput sequencing readout of growth enrichment defines optimal gene expression elements for homoethanologenesis Indro Neil Ghosh, and Robert Landick ACS Synthetic Biology, DOI: 10.1021/acssynbio.6b00121 (2016)
Predicting motor improvement after stroke with clinical assessment and diffusion tensor imaging Buch, ER; Rizk, S; Nicolo, P; Cohen, LG; Schnider, A; Guggisberg, AG; Neurology, DOI://10.1212/WNL.0000000000002675 (2016)

Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions Villarino A, Laurence A, Robinson GW, Bonelli M, Dema B, Afzali B, Shih HY, Sun HW, Brooks SR, Hennighausen L, Kanno Y, O'Shea JJ Elife, doi: 10.7554/eLife.08384 (2016)
Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality Han-Yu Shih, Giuseppe Sciumè, Yohei Mikami, Liying Guo, Hong-Wei Sun, Stephen R. Brooks, Joseph F. Urban Jr., Fred P. Davis, Yuka Kanno, John J. O'Shea Cell, doi:10.1016/j.cell.2016.04.029 (2016)
BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin Ballachanda N Devaiah, Chanelle Case-Borden, Anne Gegonne, Chih Hao Hsu, Qingrong Chen, Daoud Meerzaman, Anup Dey, Keiko Ozato & Dinah S Singer Nature Structural & Molecular Biology, doi:10.1038/nsmb.3228 (2016)
Temporal Stability of the Human Skin Microbiome Julia Oh, Allyson L. Byrd , Morgan Park , NISC Comparative Sequencing Program, Heidi H. Kong, Julia A. Segre Cell, doi://10.1016/j.cell.2016.04.008 (2016)
Colorectal Cancer and the Human Gut Microbiome: Reproducibility with Whole-Genome Shotgun Sequencing Emily Vogtmann, Xing Hua, Georg Zeller, Shinichi Sunagawa, Anita Y. Voigt, Rajna Hercog, James J. Goedert, Jianxin Shi, Peer Bork, Rashmi Sinha PLoS One, doi://10.1371/journal.pone.0155362 (2016)
Cryo-EM analysis of the conformational landscape of human P-glycoprotein (ABCB1) during its catalytic cycle Gabriel Frank, Suneet Shukla, Prashant Rao, Mario J Borgnia, Alberto Bartesaghi, Alan Merk, Aerfa Mobin, Lothar Esser, Lesley A. Earl, Michael M Gottesman, Di Xia, Suresh V. Ambudkar, and Sriram Subramaniam Molecular Pharmacology, doi: 10.1124/mol.116.104190 (2016)

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody Kong, R; Xu, K; Zhou, T et al. Science, DOI://10.1126/science.aae0474 (2016)
Analysis of mcDESPOT- and CPMG-derived parameter estimates for two-component nonexchanging systems Bouhrara M, Reiter DA, Celik H, Fishbein KW, Kijowski R, Spencer RG Magn Reson Med, DOI://10.1002/mrm.25801 (2016)
Interferon Regulator Factor 8 (IRF8) Limits Ocular Pathology during HSV-1 Infection by Restraining the Activation and Expansion of CD8+ T Cells Sun, L; St Leger, AJ; Yu, CR et al. PLoS ONE, DOI://10.1371/journal.pone.0155420 (2016)
Delineation of Polypharmacology across the Human Structural Kinome Using a Functional Site Interaction Fingerprint Approach Zhao Z, Xie L, Xie L, Bourne PE J. Med. Chem., DOI://10.1021/acs.jmedchem.5b02041 (2016)
Distinct epigenetic features of differentiation-regulated replication origins Smith, OK; Kim, R; Fu, H et al. Epigenetics Chromatin, DOI://10.1186/s13072-016-0067-3 (2016)
Structural Determinants of Misfolding in Multidomain Proteins Pengfei Tian and Robert B. Best PLoS Computational Biology, 10.1371/journal.pcbi.1004933 (2016)
Learned Value Shapes Responses to Objects in Frontal and Ventral Stream Networks in Macaque Monkeys Kaskan, PM; Costa, VD; Eaton, HP et al. Cereb. Cortex, DOI://10.1093/cercor/bhw113 (2016)
CLIP-seq to Identify KSHV ORF57-Binding RNA in Host B Cells Ma Y, Liu P, Majerciak V, Zhu J, Zheng ZM Curr Protoc Microbiol, DOI://10.1002/cpmc.3 (2016)
Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G Stewart-Jones, GB; Soto, C; Lemmin, T et al. Cell, DOI://10.1016/j.cell.2016.04.010 (2016)
PA-seq for Global Identification of RNA Polyadenylation Sites of Kaposi's Sarcoma-Associated Herpesvirus Transcripts Ni T, Majerciak V, Zheng ZM, Zhu J Curr Protoc Microbiol, DOI://10.1002/cpmc.1 (2016)
Genome Sequence of the Banana Plant Growth-Promoting Rhizobacterium Pseudomonas fluorescens PS006 Gamez, RM; Rodríguez, F; Ramírez, S et al. Genome Announc, DOI://10.1128/genomeA.00329-16 (2016)
Sparse signal representation in digital and biological system Matthew Guay PhD Thesis, University of Maryland (2016)
Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways Psaila, B; Barkas, N; Iskander, D et al. Genome Biol., DOI://10.1186/s13059-016-0939-7 (2016)
Identification of an Immunogenic Subset of Metastatic Uveal Melanoma Rothermel, LD; Sabesan, AC; Stephens, DJ et al. Clin. Cancer Res., DOI://10.1158/1078-0432.CCR-15-2294 (2016)
Regional Variations in Brain Gyrification Are Associated with General Cognitive Ability in Humans Michael D. Gregory, J. Shane Kippenhan, Dwight Dickinson, Jessica Carrasco, Venkata S. Mattay, Daniel R. Weinberger, Karen F. Berman Current Biology, doi:10.1016/j.cub.2016.03.021 (2016)
A Common Polymorphism in HIBCH Influences Methylmalonic Acid Concentrations in Blood Independently of Cobalamin Anne M. Molloy, Faith Pangilinan , et al. Am. J. Hum. Genet., DOI:10.1016/j.ajhg.2016.03.005 show (2016)
Arginine kinase from Myzostoma cirriferum, a basal member of annelids Daichi Yano, Sayo Mimura, Kouji Uda, Tomohiko Suzuki Comparative Biochemistry and Physiology Part B: Biochemistry, doi:10.1016/j.cbpb.2016.04.004 (2016)
TNF-α modulates genome-wide redistribution of ΔNp63α/TAp73 and NF-κB cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer Si, H; Lu, H; Yang, X et al. Oncogene, DOI://10.1038/onc.2016.112 (2016)
DR-TAMAS: Diffeomorphic Registration for Tensor Accurate Alignment of Anatomical Structures Irfanoglu, MO; Nayak, A; Jenkins, J et al. Neuroimage, DOI://10.1016/j.neuroimage.2016.02.066 (2016)
Challenges in studying the structures of metal- amyloid oligomers related to type 2 diabetes, parkinson's disease, and alzheimer's disease Vered Wineman-Fisher, Daniel Nir Bloch, Yifat Miller Coordination Chemistry Reviews, doi:10.1016/j.ccr.2016.04.010 (2016)
Using cryo-EM to map small ligands on dynamic metabolic enzymes: Studies with glutamate dehydrogenase Mario J. Borgnia, Soojay Banerjee, Alan Merk, Doreen Matthies, Alberto Bartesaghi, Prashant Rao, Jason Pierson, Lesley A. Earl, Veronica Falconieri, Sriram Subramaniam, and Jacqueline L. S. Milne Molecular Pharmacology, doi: 10.1124/mol.116.103382 (2016)
Membrane-associated Ras dimers are isoform-specific: K-Ras dimers differ from H-Ras dimers Hyunbum Jang, Serena Muratcioglu, Attila Gursoy, Ozlem Keskin, Ruth Nussinov Biochemical J., DOI: 10.1042/BCJ20160031 (2016)
Plasmid-Based Materials as Multiplex Quality Controls and Calibrators for Clinical Next-Generation Sequencing Assays David J. Sims, Robin D. Harrington, Eric C. Polley, Thomas D. Forbes, Michele G. Mehaffey, Paul M. McGregor III, Corinne E. Camalier, Kneshay N. Harper, Courtney H. Bouk, Biswajit Das, Barbara A. Conley, James H. Doroshow, P. Mickey Williams, Chih-Jian Lih J. Molecular Diagnostics, doi:10.1016/j.jmoldx.2015.11.008 (2016)
High-level expression of Proteinase K from Tritirachium album Limber in Pichia pastoris using multi-copy expression strains Yang, H; Zhai, C; Yu, X et al. Protein Expr. Purif., DOI://10.1016/j.pep.2016.02.006 (2016)

Laminopathies disrupt epigenomic developmental programs and cell fate Perovanovic, J; Dell'Orso, S; Gnochi, VF et al. Sci Transl Med, DOI://10.1126/scitranslmed.aad4991 (2016)
Tracking brain arousal fluctuations with fMRI Chang, C; Leopold, DA; Schölvinck, ML et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1520613113 (2016)
Structure-based designing of sordarin derivative as potential fungicide with pan-fungal activity Biprashekhar Chakrabortya, Nikunjkumar Vinodray Sejpalb, Pavan V. Payghana, Nanda Ghoshala, Jayati Sengupta J. Mol. Graph. Model. , doi:10.1016/j.jmgm.2016.03.013 (2016)
The Ancient Evolutionary History of Polyomaviruses Buck, CB; Van Doorslaer, K; Peretti, A et al. PLoS Pathog., DOI://10.1371/journal.ppat.1005574 (2016)
BIG: A large-scale data integration tool for renal physiology Yue Zhao, Chin-Rang Yang, Viswanathan Raghuram, Jaya Parulekar, Mark A. Knepper Am. J. Physiol. Renal Physiol. , DOI: 10.1152/ajprenal.00249.2016 (2016)
An Integrated Genome-Wide Systems Genetics Screen for Breast Cancer Metastasis Susceptibility Genes Ling Bai, Howard H. Yang, Ying Hu, Anjali Shukla, Ngoc-Han Ha, Anthony Doran, Farhoud Faraji, Natalie Goldberger, Maxwell P. Lee, Thomas Keane, Kent W. Hunter PLoS Genetics, doi://10.1371/journal.pgen.1005989 (2016)

Biallelic BRCA2 Mutations Shape the Somatic Mutational Landscape of Aggressive Prostate Tumors Brennan Decker, Danielle M. Karyadi, Brian W. Davis, Eric Karlins, Lori S. Tillmans, Janet L. Stanford, Stephen N. Thibodeau, Elaine A. Ostrander Am. J. Hum. Genet. , doi:10.1016/j.ajhg.2016.03.003 (2016)
Characterization of influenza vaccine hemagglutinin complexes by cryo-electron microscopy and image analyses reveals structural polymorphisms Dustin M. McCraw, John R. Gallagher and Audray K. Harris Clin. Vaccine Immunol. , doi:10.1128/CVI.00085-16 (2016)
Adaptation of pancreatic islet cyto-architecture during development Deborah A Striegel, Manami Hara and Vipul Periwal Physical Biology, doi://10.1088/1478-3975/13/2/025004 (2016)
Low-frequency and common genetic variation in ischemic stroke R Malik, M Traylor et al. Neurology, doi://10.1212/WNL.0000000000002528 (2016)
Purine (N)-Methanocarba Nucleoside Derivatives Lacking an Exocyclic Amine as Selective A3 Adenosine Receptor Agonists Tosh, DK; Ciancetta, A; Warnick, E et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.5b01998 (2016)
Comparison of normalization and differential expression analyses using RNA-Seq data from 726 individual Drosophila melanogaster Lin Y, Golovnina K, Chen ZX, Lee HN, Negron YL, Sultana H, Oliver B, Harbison ST BMC Genomics, doi: 10.1186/s12864-015-2353-z (2016)

Novel Analogues of (R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity Zou, MF; Keck, TM; Kumar, V et al. J. Med. Chem., DOI://10.1021/acs.jmedchem.5b01612 (2016)
Fatty Acid Oxidation is Impaired in An Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease Menezes LF, Lin CC, Zhou F, Germino GG EBioMedicine, 2352-3964 (2016)
Temperature-Dependent Conformational Properties of Human Neuronal Calcium Sensor-1 Protein Revealed by All-Atom Simulations Zhu Y, Ma B, Qi R, Nussinov R, Zhang Q J Phys Chem B, DOI://10.1021/acs.jpcb.5b12299 (2016)
Linear Discriminant Analysis Achieves High Classification Accuracy for the BOLD fMRI Response to Naturalistic Movie Stimuli Mandelkow, H; de Zwart, JA; Duyn, JH; Front Hum Neurosci, DOI://10.3389/fnhum.2016.00128 (2016)
Evidence for N-Terminal Myristoylation of Tetrahymena Arginine Kinase Using Peptide Mass Fingerprinting Analysis Shou Motomura, Tomohiko Suzuki Protein J. , doi://10.1007/s10930-016-9663-0 (2016)
Axial superresolution via multiangle TIRF microscopy with sequential imaging and photobleaching Yan Fu, Peter W. Winter, Raul Rojas, Victor Wang, Matthew McAuliffe, and George H. Patterson PNAS, doi: 10.1073/pnas.1516715113 (2016)

Repertoires of Spike Avalanches Are Modulated by Behavior and Novelty Tiago L. Ribeiro, Sidarta Ribeiro and Mauro Copelli Frontiers in Neural Circuits, doi:///10.3389/fncir.2016.00016 (2016)
Characterization of the platelet transcriptome by RNA sequencing in patients with acute myocardial infarction Eicher, JD; Wakabayashi, Y; Vitseva, O et al. Platelets, DOI://10.3109/09537104.2015.1083543 (2016)
The Human Physiome: how standards, software and innovative service infrastructures are providing the building blocks to make it achievable Nickerson, D; Atalag, K; de Bono, B et al. Interface Focus, DOI://10.1098/rsfs.2015.0103 (2016)
Distinguishing highly similar gene isoforms with a clustering-based bioinformatics analysis of PacBio single-molecule long reads Liang, M; Raley, C; Zheng, X et al. BioData Min, DOI://10.1186/s13040-016-0090-8 (2016)
Structure and function of the AAA+ ATPase p97/Cdc48p Xia D, Tang WK, Ye Y Gene, DOI://10.1016/j.gene.2016.02.042 (2016)
Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome Falcone, EL; Abusleme, L; Swamydas, M et al. Microbiome, DOI://10.1186/s40168-016-0159-0 (2016)

MultiDimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A Report from the Center for Cancer Research Wendy Chang, Andrew Brohl, Rajesh Patidar, Sivasish Sindiri, Jack F. Shern, Jun S. Wei, Young K. Song, Marielle E Yohe, Berkley E. Gryder, Shile Zhang, Kathleen A Calzone, Nityashree Shivaprasad, Xinyu Wen, Thomas Badgett, Markku Miettinen, Kip R Hartman, James C League-Pascual, Toby Trahair, Brigitte C. Widemann, Melinda S. Merchant, Rosandra N Kaplan, Jimmy C Lin, and Javed Khan Clinical Cancer Research, doi: 10.1158/1078-0432.CCR-15-2717 (2016)
Aberrant intrinsic functional connectivity within and between corticostriatal and temporal-parietal networks in adults and youth with bipolar disorder Stoddard, J; Gotts, SJ; Brotman, MA et al. Psychol Med, DOI://10.1017/S0033291716000143 (2016)
Cajal bodies are linked to genome conformation Qiuyan Wang, Iain A. Sawyer, Myong-Hee Sung, David Sturgill, Sergey P. Shevtsov, Gianluca Pegoraro, Ofir Hakim, Songjoon Baek, Gordon L. Hager & Miroslav Dundr Nature Communications, doi:10.1038/ncomms10966 (2016)
Cryo-electron Microscopy Structures of Chimeric Hemagglutinin Displayed on a Universal Influenza Vaccine Candidate Erin E. H. Tran, Kira A. Podolsky, Alberto Bartesaghi, Oleg Kuybeda, Giovanna Grandinetti, Teddy John Wohlbold, Gene S. Tan, Raffael Nachbagauer, Peter Palese, Florian Krammer, Sriram Subramaniam mBio, doi: 10.1128/mBio.00257-16 (2016)
Subtle in-scanner motion biases automated measurement of brain anatomy from in vivo MRI Aaron Alexander-Bloch, Liv Clasen, Michael Stockman, Lisa Ronan, Francois Lalonde, Jay Giedd and Armin Raznahan Human Brain Mapping, DOI: 10.1002/hbm.23180 (2016)
Detection of benign prostatic hyperplasia nodules in T2W MR images using fuzzy decision forest Nathan Lay ; Sabrina Freeman ; Baris Turkbey ; Ronald Summers SPIE Proceedings, doi:10.1117/12.2217906 (2016)

2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition Soojay Banerjee, Alberto Bartesaghi, Alan Merk, Prashant Rao, Stacie L. Bulfer, Yongzhao Yan, Neal Green, Barbara Mroczkowski, R. Jeffrey Neitz, Peter Wipf, Veronica Falconieri, Raymond J. Deshaies, Jacqueline L. S. Milne, Donna Huryn, Michelle Arkin, Sriram Subramaniam Science, DOI: 10.1126/science.aad7974 (2016)
Design and synthesis of small molecule-sulfotyrosine mimetics that inhibit HIV-1 entry Dogo-Isonagie, C; Lee, SL; Lohith, K et al. Bioorg. Med. Chem., DOI://10.1016/j.bmc.2016.02.044 (2016)
Detection and Whole-Genome Sequencing of Carbapenemase-Producing Aeromonas hydrophila Isolates from Routine Perirectal Surveillance Culture Hughes, HY; Conlan, SP; Lau, AF et al. J. Clin. Microbiol., DOI://10.1128/JCM.03229-15 (2016)
Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers Robles, AI; Traverso, G; Zhang, M et al. Gastroenterology, DOI://10.1053/j.gastro.2015.12.036 (2016)
Emerging Functions of Natural IgM and Its Fc Receptor FCMR in Immune Homeostasis Wang, H; Coligan, JE; Morse, HC; Front Immunol, DOI://10.3389/fimmu.2016.00099 (2016)
A molecular threshold for effector CD8(+) T cell differentiation controlled by transcription factors Blimp-1 and T-bet Xin, A; Masson, F; Liao, Y et al. Nat. Immunol., DOI://10.1038/ni.3410 (2016)

caOmicsV: an R package for visualizing multidimensional cancer genomic data Zhang H, Meltzer PS, Davis SR BMC Bioinformatics, DOI://10.1186/s12859-016-0989-6 (2016)
Brain-Derived Neurotrophic Factor Val66Met Polymorphism Affects the Relationship Between an Anxiety-Related Personality Trait and Resting Regional Cerebral Blood Flow Wei, SM; Eisenberg, DP; Nabel, KG et al. Cereb. Cortex, DOI://10.1093/cercor/bhw072 (2016)
Redox-induced activation of the proton pump in the respiratory complex I Vivek Sharma, Galina Belevich, Ana P. Gamiz-Hernandez, Tomasz Ròg, Ilpo Vattulainen, Marina L. Verkhovskaya Mårten Wikström, Gerhard Hummer, and Ville R. I. Kaila PNAS, doi://10.1073/pnas.1503761112 (2016)
High-level expression and characterization of a novel serine protease in Pichia pastoris by multi-copy integration Min Shu, Wei Shen, Shihui Yang , Xiaojuan Wang , Fei Wang , Yaping Wang , Lixin Ma Enzyme and Microbioal Technology, doi:10.1016/j.enzmictec.2016.06.007 (2016)
NMDA Receptors Multiplicatively Scale Visual Signals and Enhance Directional Motion Discrimination in Retinal Ganglion Cells Poleg-Polsky A, Diamond JS Neuron, DOI://10.1016/j.neuron.2016.02.013 (2016)
MEGSA: A Powerful and Flexible Framework for Analyzing Mutual Exclusivity of Tumor Mutations Xing Hua, Paula L. Hyland, Jing Huang, Lei Song, Bin Zhu, Neil E. Caporaso, Maria Teresa Landi, Nilanjan Chatterjee, and Jianxin Shi Am J. Hum. Genet. , doi://10.1016/j.ajhg.2015.12.021 (2016)

Characterizing the Covalent Targets of a Small Molecule Inhibitor of the Lysine Acetyltransferase P300 Shrimp JH, Sorum AW, Garlick JM, Guasch L, Nicklaus MC, Meier JL ACS Med Chem Lett, DOI://10.1021/acsmedchemlett.5b00385 (2016)
Plasticity of Sensorimotor Networks: Multiple Overlapping Mechanisms Buch, ER; Liew, SL; Cohen, LG; Neuroscientist, DOI://10.1177/1073858416638641 (2016)
Critical Nucleus Structure and Aggregation Mechanism of the C-terminal Fragment of Copper-Zinc Superoxide Dismutase Protein Zou Y, Sun Y, Zhu Y, Ma B, Nussinov R, Zhang Q ACS Chem Neurosci, DOI://10.1021/acschemneuro.5b00242 (2016)
Seeking Optimal Region-Of-Interest (ROI) Single-Value Summary Measures for fMRI Studies in Imaging Genetics Tong, Y; Chen, Q; Nichols, TE et al. PLoS ONE, DOI://10.1371/journal.pone.0151391 (2016)
Microscopic interpretation of folding φ-values using the transition path ensemble Robert B. Best and Gerhard Hummer PNAS, doi: 10.1073/pnas.1520864113 (2016)
Structural insights of a PI3K/mTOR dual inhibitor with the morpholino-triazine scaffold Takako Takeda, Yanli Wang , Stephen H. Bryant J. Computer-Aided Molecular Design, doi://10.1007/s10822-016-9905-4 (2016)

Modulation of Folding Internal Friction by Local and Global Barrier Heights Wenwei Zheng, David de Sancho, and Robert B. Best J. Phys. Chem. Letters, DOI: 10.1021/acs.jpclett.6b00329 (2016)
The ISW1 and CHD1 ATP-dependent chromatin remodelers compete to set nucleosome spacing in vivo Josefina Ocampo, Razvan V. Chereji, Peter R. Eriksson and David J. Clark Nucleic Acids Research, doi://10.1093/nar/gkw068 (2016)
Biointeractions of ultrasmall glutathione-coated gold nanoparticles: effect of small size variations Alioscka A. Sousa, Sergio A. Hassan, Luiza L. Knittel, Andrea Balbo, Maria A. Aronova, Patrick H. Brown, Peter Schuck and Richard D. Leapman Nanoscale, DOI: 10.1039/C5NR07642K (2016)
The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes Rinschen, MM; Bharill, P; Wu, X et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddw016 (2016)
Mucolipidosis types II and III and non-syndromic stuttering are associated with different variants in the same genes Raza, MH; Domingues, CE; Webster, R et al. Eur. J. Hum. Genet., DOI://10.1038/ejhg.2015.154 (2016)
The Use of Minimal RNA Toeholds to Trigger the Activation of Multiple Functionalities Afonin, KA; Viard, M; Tedbury, P et al. Nano Lett., DOI://10.1021/acs.nanolett.5b04676 (2016)

Deep Convolutional Neural Networks for Computer-Aided Detection: CNN Architectures, Dataset Characteristics and Transfer Learning Hoo-Chang Shin Holger R. Roth ; Mingchen Gao ; Le Lu ; Ziyue Xu ; Isabella Nogues ; Jianhua Yao ; Daniel Mollura ; Ronald M. Summers IEEE Transactions on Medical Imaging, DOI://10.1109/TMI.2016.2528162 (2016)
Preterm birth and air pollution: Critical windows of exposure for women with asthma Pauline Mendola, Maeve Wallace, Beom Seuk Hwang, Danping Liu, Candace Robledo, Tuija Mӓnnistö, Rajeshwari Sundaram, Seth Sherman, Qi Ying, Katherine L. Grantz J. Allergy Clin. Immunology, doi:10.1016/j.jaci.2015.12.1309 (2016)
Necdin is a breast cancer metastasis suppressor that regulates the transcription of c-Myc Minnkyong Lee, Sarah M. Beggs, Derek Gildea, Sujata Bupp, Jens Lichtenberg, Niraj S. Trivedi, NISC Comparative Sequencing Program, Ying Hu, David M. Bodine, and Nigel P.S. Crawford1 Oncotarget, doi: 10.18632/oncotarget.5230 (2016)
Genome-wide footprinting: ready for prime time? Myong-Hee Sung, Songjoon Baek & Gordon L Hager Nature Methods, doi:10.1038/nmeth.3766 (2016)
A Comparison of Methods to Reweight from Classical Molecular Simulations to QM/MM Potentials Eric Christopher Dybeck, Gerhard König, Bernard R. Brooks, and Michael R. Shirts J. Chem. Theory. Comput, DOI: 10.1021/acs.jctc.5b01188 (2016)
Multistrand Structure Prediction of Nucleic Acid Assemblies and Design of RNA Switches Eckart Bindewald, Kirill A. Afonin, Mathias Viard, Paul Zakrevsky, Taejin Kim, and Bruce A. Shapiro Nano Letters, DOI: 10.1021/acs.nanolett.5b04651 (2016)

Understanding the Mechanism of the Hydrogen Abstraction from Arachidonic Acid Catalyzed by the Human Enzyme 15-Lipoxygenase-2. A Quantum Mechanics/Molecular Mechanics Free Energy Simulation Reynier Suardiaz, Pablo Garcia Jambrina, Laura Masgrau, Ángels Gonzàlez-Lafont, Edina Rosta, and Josè M. Lluch J. Chem. Theory. Comput, DOI: 10.1021/acs.jctc.5b01236 (2016)
Impact of time-of-day on brain morphometric measures derived from T₁-weighted magnetic resonance imaging Aaron Trefler, Neda Sadeghi, Adam G. Thomas, Carlo Pierpaoli, Chris I. Baker, Cibu Thomas Neuroimage, doi:10.1016/j.neuroimage.2016.02.034 (2016)
Enhancer of Rudimentary Cooperates with Conserved RNA-Processing Factors to Promote Meiotic mRNA Decay and Facultative Heterochromatin Assembly Sugiyama, T; Thillainadesan, G; Chalamcharla, VR et al. Mol. Cell, DOI://10.1016/j.molcel.2016.01.029 (2016)
Production of small cysteine-rich effector proteins in Escherichia coli for structural and functional studies Xiaoxiao Zhang, Neal Nguyen, Susan Breen, Megan A. Outram, Peter N. Dodds, Bostjan Kobe, Peter S. Solomon and Simon J. Williams Molecular Plant Pathology, DOI: 10.1111/mpp.12385 (2016)
Deubiquitylation of protein cargo is not an essential step in exosome formation Alyssa R. Huebner, Lei Cheng, Poorichaya Somparn, Mark A. Knepper, Robert A. Fenton and Trairak Pisitkun Molecular and Cellular Proteomics, doi: 10.1074/mcp.M115.054965 (2016)
A Helitron transposon reconstructed from bats reveals a novel mechanism of genome shuffling in eukaryotes Grabundzija, I; Messing, SA; Thomas, J et al. Nat Commun, DOI://10.1038/ncomms10716 (2016)
Mechanism of Protein Molecule Isolation by IR Laser Ablation of Droplet Beam Kensuke Komatsu, Takuya Nirasawa, Mariko Hoshino-Nagasaka, and Jun-ya Kohno J. Phys. Chem. A, DOI: 10.1021/acs.jpca.5b10873 (2016)
A genome landscape of SRSF3-regulated splicing events and gene expression in human osteosarcoma U2OS cells Ajiro M, Jia R, Yang Y, Zhu J, Zheng ZM Nucleic Acids Res., DOI://10.1093/nar/gkv1500 (2016)
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients Alena Gros, Maria R Parkhurst, Eric Tran, Anna Pasetto, Paul F Robbins, Sadia Ilyas, Todd D Prickett, Jared J Gartner, Jessica S Crystal, Ilana M Roberts, Kasia Trebska-McGowan, John R Wunderlich, James C Yang & Steven A Rosenberg Nature Medicine, doi:10.1038/nm.4051 (2016)
Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts Liang Ma, Zehua Chen, Da Wei Huang et. al. Nature Communications, doi:10.1038/ncomms10740 (2016)
Gene-Based Association Analysis for Censored Traits Via Fixed Effect Functional Regressions. Fan R, Wang Y, Yan Q, Ding Y, Weeks DE, Lu Z, Ren H, Cook RJ, Xiong M, Swaroop A, Chew EY, Chen W Genet Epidemiol. , doi: 10.1002/gepi.21947 (2016)
Finite sample pointwise confidence intervals for a survival distribution with right-censored data Michael P. Fay and Erica H. Brittain Statistics in Medicine, DOI: 10.1002/sim.6905 (2016)

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept Franke, B; Stein, JL; Ripke, S et al. Nat. Neurosci., DOI://10.1038/nn.4228 (2016)
High-throughput single-molecule screen for small-molecule perturbation of splicing and transcription kinetics Day CR, Chen H, Coulon A, Meier JL, Larson DR, Methods, DOI://10.1016/j.ymeth.2015.11.025 (2016)
Resolving the Complexity of Human Skin Metagenomes Using Single-Molecule Sequencing Yu-Chih Tsai, Sean Conlan, Clayton Deming, NISC Comparative Sequencing Program, Julia A. Segre, Heidi H. Kong Jonas Korlach, and Julia Oh mBio, doi: 10.1128/mBio.01948-15 (2016)
Recessive mutations of TMC1 associated with moderate to severe hearing loss Ayesha Imtiaz , Azra Maqsood , Atteeq U. Rehman, Robert J. Morell, Jeffrey R. Holt, Thomas B. Friedman, Sadaf Naz Neurogenetics, DOI 10.1007/s10048-016-0477-1 (2016)
Light-regulated Molecular Trafficking in a Synthetic Water-soluble Host Jesús del Barrio, Sean T. J. Ryan, Pablo G. Jambrina, Edina Rosta, and Oren A Scherman JACS, DOI: 10.1021/jacs.5b11642 (2016)
Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating Doreen Matthies, Olivier Dalmas, Mario J. Borgnia, Pawel K. Dominik, Alan Merk, Prashant Rao, Bharat G. Reddy, Shahidul Islam, Alberto Bartesaghi, Eduardo Perozo, Sriram Subramaniam Cell, doi:10.1016/j.cell.2015.12.055 (2016)

Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin Chanhyung Bae, Claudio Anselmi, Jeet Kalia, Andres Jara-Oseguera, Charles D Schwieters, Dmitriy Krepkiy ,Chul Won Lee, Eun-Hee Kim, Jae Il Kim, Josè D Faraldo-Gòmez and Kenton J Swartz eLife, DOI: http://dx.doi.org/10.7554/eLife.11273 (2016)
Self-aggregation and coaggregation of the p53 core fragment with its aggregation gatekeeper variant Jiangtao Lei , Ruxi Qi , Guanghong Wei , Ruth Nussinov and Buyong Ma Phys. Chem. Chem. Phys., DOI: 10.1039/C5CP06538K (2016)
Cutting Edge: Expression of IRF8 in Gastric Epithelial Cells Confers Protective Innate Immunity against Helicobacter pylori Infection Yan, M; Wang, H; Sun, J et al. J. Immunol., DOI://10.4049/jimmunol.1500766 (2016)
Genome-Wide Chromatin Landscape Transitions Identify Novel Pathways in Early Commitment to Osteoblast Differentiation Thompson B, Varticovski L, Baek S, Hager GL PLoS ONE, DOI://10.1371/journal.pone.0148619 (2016)
Drug repurposing to target Ebola virus replication and virulence using structural systems pharmacology Zhao Z, Martin C, Fan R, Bourne PE, Xie L BMC Bioinformatics, DOI://10.1186/s12859-016-0941-9 (2016)
Vibratory Urticaria Associated with a Missense Variant in ADGRE2 Boyden, SE; Desai, A; Cruse, G et al. N. Engl. J. Med., DOI://10.1056/NEJMoa1500611 (2016)

Identifying subgroups of enhanced predictive accuracy from longitudinal biomarker data by using tree-based approaches: applications to fetal growth Jared C. Foster, Danping Liu, Paul S. Albert and Aiyi Liu Journal of the Royal Statistical Society: Series A (Statisti, 10.1111/rssa.12182 (2016)
How Does Hyperphopsphorylation Promote Tau Aggregation and Modulate Filament Structure and Stability? Liang Xu, Jie Zheng, Martin Margittai, Ruth Nussinov, and Buyong Ma ACS Chemical Neuroscience, 10.1021/acschemneuro.5b00294 (2016)
In vivo tissue has non-linear rheological behavior distinct from 3D biomimetic hydrogels, as determined by AMOTIV microscopy Blehm BH, Devine A, Staunton JR, Tanner K Biomaterials, DOI://10.1016/j.biomaterials.2015.12.019 (2016)
Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium van den Berg, SM; de Moor, MH; Verweij, KJ et al. Behav. Genet., DOI://10.1007/s10519-015-9735-5 (2016)
Draft Genome Sequence of a Klebsiella pneumoniae Carbapenemase-Positive Sequence Type 111 Pseudomonas aeruginosa Strain Dotson GA, , Dekker JP, Palmore TN, Segre JA, Conlan S Genome Announc, DOI://10.1128/genomeA.01663-15 (2016)
The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1 Dell'Orso, S; Wang, AH; Shih, HY et al. Cell Rep, 2211-1247 (2016)

Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice Davies, B; Hatton, E; Altemose, N et al. Nature, DOI://10.1038/nature16931 (2016)
r2VIM: A new variable selection method for random forests in genome-wide association studies Silke Szymczak, Emily Holzinger, Abhijit Dasgupta, James D. Malley, Anne M. Molloy, James L. Mills, Lawrence C. Brody, Dwight Stambolian and Joan E. Bailey-Wilson BioData Mining, 10.1186/s13040-016-0087-3 (2016)
Identification of Microorganisms by High Resolution Tandem Mass Spectrometry with Accurate Statistical Significance Gelio Alves, Guanghui Wang, Aleksey Y. Ogurtsov, Steven K. Drake, Marjan Gucek, Anthony F. Suffredini, David B. Sacks, Yi-Kuo Yu J Am Soc Mass Spectrom 27:194-210, 10.1007/s13361-015-1271-2 (2016)
CircInteractome: A web tool for exploring circular RNAs and their interacting proteins and microRNAs Dudekula, DB; Panda, AC; Grammatikakis, I; De, S; Abdelmohsen, K; Gorospe, M; RNA Biol, DOI://10.1080/15476286.2015.1128065 (2016)
Somatic mutational landscape of AML with inv(16) or t(8;21) identifies patterns of clonal evolution in relapse leukemia Sood, R; Hansen, NF; Donovan, FX et al. Leukemia, DOI://10.1038/leu.2015.141 (2016)
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function Pattaro, C; Teumer, A; Gorski, M et al. Nat Commun, DOI://10.1038/ncomms10023 (2016)

Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium Ma, Y; Follis, JL; Smith, CE et al. Am. J. Clin. Nutr., DOI://10.3945/ajcn.115.112987 (2016)
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk Lu, Y; Day, FR; Gustafsson, S et al. Nat Commun, DOI://10.1038/ncomms10495 (2016)
Is the MC1R variant p. R160W associated with Parkinson's? Lubbe, SJ; Escott-Price, V; Brice, A et al. Ann. Neurol., DOI://10.1002/ana.24527 (2016)
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels Kilpeläinen, TO; Carli, JF; Skowronski, AA et al. Nat Commun, DOI://10.1038/ncomms10494 (2016)
Comparison of the Conformations of KRAS Isoforms, K-Ras4A and K-Ras4B, Points to Similarities and Significant Differences Mayukh Chakrabarti, Hyunbum Jang, and Ruth Nussinov J. Phys. Chem. B, DOI: 10.1021/acs.jpcb.5b11110 (2016)
Risk of End-stage Renal Disease in Patients with Lupus Nephritis, 1970 to 2015 A systematic review and Bayesian meta-analysis Maria G. Tektonidou, Abhijit Dasgupta and Michael M. Ward Arthritis and Rheumatology, DOI: 10.1002/art.39594 (2016)

Coupling of the Non-Amyloid-Component (NAC) Domain and the KTK(E/Q)GV Repeats Stabilize the α-Synuclein Fibrils Liang Xu, Ruth Nussinov, Buyong Ma Eur. J. Med. Chem. , doi:10.1016/j.ejmech.2016.01.044 (2016)
Novel nucleosomal particles containing core histones and linker DNA but no histone H1 Cole, HA; Cui, F; Ocampo, J et al. Nucleic Acids Res., DOI://10.1093/nar/gkv943 (2016)
Role of the D1-D2 Linker of Human VCP/p97 in the Asymmetry and ATPase Activity of the D1-domain Tang WK, Xia D Sci Rep, DOI://10.1038/srep20037 (2016)
Epigenetic regulation of hematopoiesis by DNA methylation Gore, AV; Athans, B; Iben, JR et al. Elife, DOI://10.7554/eLife.11813 (2016)
The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl Dine, JL; O'Sullivan, CC; Voeller, D et al. Breast Cancer Res. Treat., DOI://10.1007/s10549-015-3673-z (2016)
Post-transcriptional Control of Tumor Cell Autonomous Metastatic Potential by CCR4-NOT Deadenylase CNOT7 Faraji, F; Hu, Y; Yang, HH et al. PLoS Genet., DOI://10.1371/journal.pgen.1005820 (2016)

Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study Liping Hou, Urs Heilbronner et al. Lancet, doi:10.1016/S0140-6736(16)00143-4 (2016)
Autosomal-Recessive Hearing Impairment due to Rare Missense Variants within S1PR2 Regie Lyn P. Santos-Cortez, Rabia Faridi, Atteeq U. Rehman et al. American Journal of Human Genetics, doi://10.1016/j.ajhg.2015.12.004 (2016)
Nanopore Sequencing as a Rapidly Deployable Ebola Outbreak Tool Thomas Hoenen, Allison Groseth, Kyle Rosenke et al. Emerging Infectious Diseases, doi: 10.3201/eid2202.151796. (2016)
Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment Zhong, C; Cui, K; Wilhelm, C et al. Nat. Immunol., DOI://10.1038/ni.3318 (2016)
Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for Cellular Therapy Sukumar, M; Liu, J; Mehta, GU et al. Cell Metab., DOI://10.1016/j.cmet.2015.11.002 (2016)
Reliability of 7T (1) H-MRS measured human prefrontal cortex glutamate, glutamine, and glutathione signals using an adapted echo time optimized PRESS sequence: A between- and within-sessions investigation Lally, N; An, L; Banerjee, D et al. J Magn Reson Imaging, DOI://10.1002/jmri.24970 (2016)

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration de Vries, PS; Chasman, DI; Sabater-Lleal, M et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddv454 (2016)
PubChem Substance and Compound databases Kim, S; Thiessen, PA; Bolton, EE et al. Nucleic Acids Res., DOI://10.1093/nar/gkv951 (2016)
Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes Lorenzi, H; Khan, A; Behnke, MS et al. Nat Commun, DOI://10.1038/ncomms10147 (2016)
SBR-Blood: systems biology repository for hematopoietic cells Lichtenberg, J; Heuston, EF; Mishra, T; Keller, CA; Hardison, RC; Bodine, DM; Nucleic Acids Res., DOI://10.1093/nar/gkv1263 (2016)
GABBR1 and SLC6A1, Two Genes Involved in Modulation of GABA Synaptic Transmission, Influence Risk for Alcoholism: Results from Three Ethnically Diverse Populations Enoch, MA; Hodgkinson, CA; Shen, PH et al. Alcohol. Clin. Exp. Res., DOI://10.1111/acer.12929 (2016)
SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery Saxena, N; Maio, N; Crooks, DR et al. J. Natl. Cancer Inst., DOI://10.1093/jnci/djv287 (2016)

Evolutionary Dynamics of Influenza A Viruses in US Exhibition Swine Nelson, MI; Wentworth, DE; Das, SR et al. J. Infect. Dis., DOI://10.1093/infdis/jiv399 (2016)

2015 (340 papers)

miR-501-3p mediates the activity-dependent regulation of the expression of AMPA receptor subunit GluA1 Hu, Z; Zhao, J; Hu, T; Luo, Y; Zhu, J; Li, Z; J. Cell Biol., DOI://10.1083/jcb.201404092 (2015)
Bayesian dose-response analysis for epidemiological studies with complex uncertainty in dose estimation Deukwoo Kwon, F. Owen Hoffman, Brian E. Moroz, Steven L. Simon Statistics in Medicine, DOI: 10.1002/sim.6635 (2015)
Augmented trial designs for evaluation of principal surrogates Erin E. Gabriel and Dean Follmann Biostatistics, 10.1093/biostatistics/kxv055 (2015)
Dimerization of the SP1 Region of HIV-1 Gag Induces a Helical Conformation and Association into Helical Bundles: Implications for Particle Assembly Datta, SA; Clark, PK; Fan, L et al. J. Virol., DOI://10.1128/JVI.02061-15 (2015)
Multivariate classification of smokers and nonsmokers using SVM-RFE on structural MRI images Ding X, Yang Y, Stein EA, Ross TJ Hum Brain Mapp, DOI://10.1002/hbm.22956 (2015)

The higher level of complexity of K-Ras4B activation at the membrane Hyunbum Jang, Avik Banerjee, Tanmay S. Chavan, Shaoyong Lu, Jian Zhang, Vadim Gaponenko and Ruth Nussinov FASEB J. , doi: 10.1096/fj.15-279091 (2015)
Mixed group of Rhizobiales microbes in lung and blood of a patient with fatal pulmonary illness Shyh-Ching Lo, Guo-Chiuan Hung, Bing jie Li, Haiyan Lei, Tianwei Li, Kenjiro Nagamine, Shien Tsai, Mark J Zucker, Ludmilla Olesnicky Int J Clin Exp Patho, 8(11), 13834-13852. (2015)
Meta-analysis of Complex Diseases at Gene Level by Generalized Functional Linear Models Ruzong Fan, Yifan Wang, Chi-yang Chiu, Wei Chen, Haobo Ren, Yun Li, Michael Boehnke, Christopher I. Amos, Jason H. Moore, Momiao Xiong Genetics, DOI: 10.1534/genetics.115.180869 (2015)
TET-catalyzed oxidation of intragenic 5-methylcytosine regulates CTCF-dependent alternative splicing Ryan J Marina, David Sturgill, Marc A Bailly, Morgan Thenoz, Garima Varma, Maria F Prigge, Kyster K Nanan, Sanjeev Shukla, Nazmul Haque, Shalini Oberdoerffer EMBO J., DOI 10.15252/embj.201593235 (2015)
RNA Polymerase III Output Is Functionally Linked to tRNA Dimethyl-G26 Modification Arimbasseri, AG; Blewett, NH; Iben, JR et al. PLoS Genet., DOI://10.1371/journal.pgen.1005671 (2015)
Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design Jason Gorman, Cinque Soto, Max M Yang, et al. Nature Structural and Molecular Biology, doi:10.1038/nsmb.3144 (2015)

ADAR2 affects mRNA coding sequence edits with only modest effects on gene expression or splicing in vivo Allissa A. Dillman, Mark R. Cookson & Dagmar Galter RNA Biology, DOI://10.1080/15476286.2015.1110675 (2015)
Controlled DNA double-strand break induction in mice reveals post-damage transcriptome stability Jeongkyu Kim, David Sturgill, Andy D. Tran, David A. Sinclair and Philipp Oberdoerffer Nucleic Acids Research, doi: 10.1093/nar/gkv1482 (2015)
Distributed acoustic cues for caller identity in macaque vocalization Makoto Fukushima, Alex M. Doyle, Matthew P. Mullarkey, Mortimer Mishkin, Bruno B. Averbeck Royal Society Open Science, DOI: 10.1098/rsos.150432 (2015)
Socioeconomic disadvantage and neural development from infancy through early childhood Chin-Lun Hung, G; Hahn, J; Alamiri, B et al. Int J Epidemiol, DOI://10.1093/ije/dyv303 (2015)
Directed and persistent movement arises from mechanochemistry of the ParA/ParB system Hu L, Vecchiarelli AG, Mizuuchi K, Neuman KC, Liu J Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1505147112 (2015)
Assessment of established HDL-C loci for association with HDL-C levels and type 2 diabetes in Pima Indians Anup K. Nair, Paolo Piaggi, Nellie A. McLean, Manmeet Kaur, Sayuko Kobes, William C. Knowler, Clifton Bogardus, Robert L. Hanson, Leslie J. Baier Diabetologia, doi://10.1007/s00125-015-3835-x (2015)

Genome-wide association study identifies African-ancestry specific variants for metabolic syndrome Tekola-Ayele, F; Doumatey, AP; Shriner, D et al. Mol. Genet. Metab., DOI://10.1016/j.ymgme.2015.10.008 (2015)
Evolutionary context for the association of γ-globin, serum uric acid, and hypertension in African Americans Shriner, D; Kumkhaek, C; Doumatey, AP et al. BMC Med. Genet., DOI://10.1186/s12881-015-0249-z (2015)
High-Affinity Interaction of the K-Ras4B Hypervariable Region with the Ras Active Site Tanmay S. Chavan, Hyunbum Jang, Lyuba Khavrutskii, Sherwin J. Abraham, Avik Banerjee, Benjamin C. Freed, Liv Johannessen, Sergey G. Tarasov, Vadim Gaponenko, Ruth Nussinov4, Nadya I. Tarasova Biophys. J. , doi:10.1016/j.bpj.2015.09.034 (2015)
Coupling between histone conformations and DNA geometry in nucleosomes on a microsecond timescale: atomistic insights into nucleosome functions Alexey K. Shaytan, Grigoriy A. Armeev, Alexander Goncearenco, Victor B. Zhurkin, David Landsman, Anna R. Panchenko J. Mol. Biol., doi:10.1016/j.jmb.2015.12.004 (2015)
Drug-Protein Hydrogen Bonds Govern the Inhibition of the ATP Hydrolysis of the Multidrug Transporter P-glycoprotein Eduardo E. Chufan, Khyati Kapoor, Suresh V. Ambudkar Biochemical Pharmacology, doi:10.1016/j.bcp.2015.12.007 (2015)
MYCN controls an alternative RNA splicing program in high-risk metastatic neuroblastoma Shile Zhang, Jun S. Wei1 , Samuel Q. Li , Tom C. Badgett , Young K. Song , Saurabh Agarwal , Cristian Coarfa , Catherine Tolman , Laura Hurd , Hongling Liao , Jianbin He , Xinyu Wen , Zhihui Liu , Carol J. Thiele , Frank Westermann , Shahab Asgharzadeh , Robert C. Seeger , John M. Maris , Jamie M. Guidry Auvil , Malcolm A. Smith , Eric D. Kolaczyk , Jason Shohet , Javed Khan Cancer Letters, doi://10.1016/j.canlet.2015.11.045 (2015)

Multi-modal characterization of rapid anterior hippocampal volume increase associated with aerobic exercise Adam G. Thomas, Andrea Dennis, Nancy B. Rawlings, Charlotte J. Stagg, Lucy Matthews, Martyn Morris, Shannon H. Kolind, Sean Foxley, Mark Jenkinson, Thomas E. Nichols, Helen Dawes, Peter A. Bandettini, Heidi Johansen-Berg NeuroImage, doi:10.1016/j.neuroimage.2015.10.090 (2015)
Allosteric stabilization of the amyloid-β peptide hairpin by the fluctuating N-terminal Liang Xu , Ruth Nussinov and Buyong Ma Chem. Commun., DOI: 10.1039/C5CC08107F (2015)
Intrinsic excitability measures track antiepileptic drug action and uncover increasing/decreasing excitability over the wake/sleep cycle Christian Meisel, Andreas Schulze-Bonhage, Dean Freestone, Mark James Cook, Peter Achermann, Dietmar Plenz PNAS, doi: 10.1073/pnas.1513716112 (2015)
Transcriptional and Chromatin Regulation during Fasting - The Genomic Era Goldstein I, Hager GL Trends Endocrinol. Metab., DOI://10.1016/j.tem.2015.09.005 (2015)
Evaluation of Genome Wide Association Study Associated Type 2 Diabetes Susceptibility Loci in Sub Saharan Africans Adeyemo, AA; Tekola-Ayele, F; Doumatey, AP et al. Front Genet, DOI://10.3389/fgene.2015.00335 (2015)
Genome Sequence of the Banana Plant Growth-Promoting Rhizobacterium Bacillus amyloliquefaciens BS006 Rocío M. Gamez, Fernando Rodríguez, Johan F. Bernal, Richa Agarwala, David Landsman, Leonardo Mariño-Ramírez Genome Announc., doi: 10.1128/genomeA.01391-15 (2015)
HIV Therapeutics and Methods of Making and Using Same Paolo Lusso and Raffaelo Cimbro Patent, United States Patent Application 20150313990 (2015)
NCICT: a computational solution to estimate organ doses for pediatric and adult patients undergoing CT scans Choonsik Lee, Kwang Pyo Kim, Wesley E Bolch, Brian E Moroz and Les Folio J. Radiological Protection, doi:10.1088/0952-4746/35/4/891 (2015)
Reduction of All-Atom Protein Folding Dynamics to One-Dimensional Diffusion Wenwei Zheng and Robert B. Best J. Phys. Chem. , DOI: 10.1021/acs.jpcb.5b09741 (2015)
Transient misfolding dominates multidomain protein folding Alessandro Borgia, Katherine R. Kemplen, Madeleine B. Borgia, Andrea Soranno, Sarah Shammas, Bengt Wunderlich, Daniel Nettels, Robert B. Best, Jane Clarke & Benjamin Schuler Nature Communications, doi:10.1038/ncomms9861 (2015)
Replicate exome-sequencing in a multiple-generation family: improved interpretation of next-generation sequencing data Praveen F. Cherukuri, Valerie Maduro, Karin V. Fuentes-Fajardo, Kevin Lam, David R. Adams, Cynthia J. Tifft, James C. Mullikin, William A. Gahl, Cornelius F. Boerkoel and NISC Comparative Sequencing Program BMC Genomics, doi:10.1186/s12864-015-2107-y (2015)
HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis Michael J. Ombrello, Elaine F. Remmers, Ioanna Tachmazidou et al and the International Childhood Arthritis Genetics (INCHARGE) Consortium PNAS, doi: 10.1073/pnas.1520779112 (2015)

Estimation of interaction effects using pooled biospecimens in a case-control study Michelle R. Danaher, Paul S. Albert, Aninyda Roy and Enrique F. Schisterman Statistics in Medicine, DOI: 10.1002/sim.6798 (2015)
Epstein-Barr virus from Burkitt Lymphoma biopsies from Africa and South America share novel LMP-1 promoter and gene variations Lei H, Li T, Li B, Tsai S, Biggar RJ, Nkrumah F, Neequaye J, Gutierrez M, Epelman S, Mbulaiteye SM, Bhatia K, Lo SC Sci Rep., doi: 10.1038/srep16706 (2015)
A 3D Searchable Database of Transgenic Zebrafish Gal4 and Cre Lines for Functional Neuroanatomy Studies Gregory D. Marquart, Kathryn M. Tabor, Mary Brown, Jennifer L. Strykowski, Gaurav K. Varshney, Matthew C. LaFave, Thomas Mueller, Shawn M. Burgess, Shin-ichi Higashijima and Harold A. Burgess Frontiers in Neural Circuits, doi://10.3389/fncir.2015.00078 (2015)
GTP Binding and Oncogenic Mutations May Attenuate Hypervariable Region (HVR)-Catalytic Domain Interactions in Small GTPase K-Ras4B, Exposing the Effector Binding Site Lu S, Banerjee A, Jang H, Zhang J, Gaponenko V, Nussinov R J. Biol. Chem., DOI://10.1074/jbc.M115.664755 (2015)
A Novel MHC-I Surface Targeted for Binding by the MCMV m06 Immunoevasin Revealed by Solution NMR Sgourakis NG, May NA, Boyd LF, Ying J, Bax A, Margulies DH J. Biol. Chem., DOI://10.1074/jbc.M115.689661 (2015)
Epidermal devices for noninvasive, precise, and continuous mapping of macrovascular and microvascular blood flow Webb, RC; Ma, Y; Krishnan, S et al. Sci Adv, DOI://10.1126/sciadv.1500701 (2015)

Clinical feasibility of using mean apparent propagator (MAP) MRI to characterize brain tissue microstructure Alexandru V. Avram, Joelle E. Sarlls, Alan S. Barnett, Evren Özarslan, Cibu Thomas, M. Okan Irfanoglu, Elizabeth Hutchinson, Carlo Pierpaoli, Peter J. Basser NeuroImage, doi:10.1016/j.neuroimage.2015.11.027 (2015)
Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma Bogen, D; Wei, JS; Azorsa, DO et al. Oncotarget, DOI://10.18632/oncotarget.6208 (2015)
Phenotypic variance explained by local ancestry in admixed African Americans Shriner, D; Bentley, AR; Doumatey, AP et al. Front Genet, DOI://10.3389/fgene.2015.00324 (2015)
Distribution and evolution of the serine/aspartate racemase family in invertebrates Kouji Uda, Keita Abe, Yoko Dehara, Kiriko Mizobata, Natsumi Sogawa, Yuki Akagi, Mai Saigan, Atanas D. Radkov, Luke A. Moe Amino Acids, doi://10.1007/s00726-015-2092-0 (2015)
Selectivity in the Use of Gi/o Proteins Is Determined by the DRF Motif in CXCR6 and Is Cell-Type Specific Satya P. Singh, John F. Foley, Hongwei H. Zhang, Darrell E. Hurt, Jennifer L. Richards, Craig S. Smith, Fang Liao, and Joshua M. Farber Molecular Pharmacology, doi: 10.1124/mol.115.099960 (2015)
The Structural Basis of Actin Organization by Vinculin and Metavinculin Laura Y. Kim, Peter M. Thompson, Hyunna T. Lee, Mihir Pershad, Sharon L. Campbell, Gregory M. Alushin J. Mol. Biol. , doi:10.1016/j.jmb.2015.09.031 (2015)

Analysis of SLC16A11 variants in 12,811 American Indians: genotype-obesity interaction for type 2 diabetes and an association with RNASEK expression Michael Traurig, Robert L. Hanson, Alejandra Marinelarena, Sayuko Kobes, Paolo Piaggi, Shelley Cole, Joanne E. Curran, John Blangero, Harald Göring, Satish Kumar, Robert G. Nelson, Barbara V. Howard, William C. Knowler, Leslie J. Baier and Clifton Bogardus Diabetes, doi: 10.2337/db15-0571 (2015)
In Search of a Cure for Proteostasis-Addicted Cancer: A AAA Target Revealed Xia D, Ye Y Cancer Cell, DOI://10.1016/j.ccell.2015.10.006 (2015)
Genome-wide estimate of the heritability of Multiple System Atrophy M. Federoff, T.R. Price, A. Sailer, S. Scholz, D. Hernandez, A. Nicolas, A.B. Singleton, M. Nalls, H. Houlden Parkinsonism and Related Disorders, doi:10.1016/j.parkreldis.2015.11.005 (2015)
Reprogramming of Polycomb-Mediated Gene Silencing in Embryonic Stem Cells by the miR-290 Family and the Methyltransferase Ash1l Chryssa Kanellopoulou, Timothy Gilpatrick, Gokhul Kilaru, Patrick Burr, Cuong K. Nguyen, Aaron Morawski, Michael J. Lenardo, Stefan A. Muljo Stem Cell Reports, doi:10.1016/j.stemcr.2015.10.001 (2015)
Resting-state functional connectivity and presynaptic monoamine signaling in Alcohol Dependence Zhu X, Dutta N, Helton SG, Schwandt M, Yan J, Hodgkinson CA, Cortes CR, Kerich M, Hall S, Sun H, Phillips M, Momenan R, Lohoff FW Hum Brain Mapp., doi: 10.1002/hbm.22951 (2015)
Effects of the C-Terminal Tail on the Conformational Dynamics of Human Neuronal Calcium Sensor-1 Protein Zhu, Y; Yang, S; Qi, R et al. J Phys Chem B, DOI://10.1021/acs.jpcb.5b07962 (2015)

ColoWeb: a resource for analysis of colocalization of genomic features Kim R, Smith OK, Wong WC, Ryan AM, Ryan MC, Aladjem MI BMC genomics, doi: 10.1186/s12864-015-1345-3. (2015)
Methylated cytosines mutate to transcription factor binding sites that drive tetrapod evolution Ximiao He, Desiree Tillo, Jeff Vierstra, Khund-Sayeed Syed, Callie Deng, Jordan G. Ray, John Stamatoyannopoulos, Peter C. Fitzgerald and Charles Vinson Genome Biol. and Evol. , doi: 10.1093/gbe/evv205 (2015)
Sequence-and Temperature-Dependent Properties of Unfolded and Disordered Proteins from Atomistic Simulations Gül H. Zerze, Robert B Best, and Jeetain Mittal J. Phys. Chem. B, DOI: 10.1021/acs.jpcb.5b08619 (2015)
Proteomic Profiling of Nuclear Fractions from Native Renal Inner Medullary Collecting Duct Cells Christina M. Pickering, Cameron R. Grady, Barbara Medvar, Milad Emamian, Pablo Concha Sandoval, Yue Zhao, Chin-Rang Yang, Hyun Jun Jung, Chung-Lin Chou, Mark A. Knepper Physiol Genomics., DOI: 10.1152/physiolgenomics.00090.2015 (2015)
Structure dependent hydrophobic and hydrophilic interactions between nickel(II) Schiff base complexes and serum albumins: Spectroscopic and docking studies Banabithi Koley Seth, Aurkie Ray, Mousumi Banerjee, Teerna Bhattacharyya, Dhananjay Bhattacharyya, Samita Basu J. Luminescence, doi:10.1016/j.jlumin.2015.11.009 (2015)
A Transcriptional Map of the Renal Tubule: Linking Structure to Function Kretzler, M; Ju, W; J. Am. Soc. Nephrol., DOI://10.1681/ASN.2015030242 (2015)
Integrated genome-wide analysis of genomic changes and gene regulation in human adrenocortical tissue samples Gara, SK; Wang, Y; Patel, D et al. Nucleic Acids Res., DOI://10.1093/nar/gkv908 (2015)
Cell Migration and Invadopodia Formation Require a Membrane-binding Domain of CARMIL2 M. Hunter Lanier, Patrick McConnell and John A. Cooper J. Biol. Chem. , doi: 10.1074/jbc.M115.676882 (2015)
An insight into the sialome of the horse fly, Tabanus bromius Ribeiro JM, Kazimirova M, Takac P, Andersen JF, Francischetti IM Insect Biochem. Mol. Biol., DOI://10.1016/j.ibmb.2015.09.002 (2015)
TCF21 hypermethylation in genetically quiescent clear cell sarcoma of the kidney Saskia L. Gooskens, Samantha Gadd, Jaime M. Guidry Auvil, Daniela S. Gerhard, Javed Khan, Rajesh Patidar, Daoud Meerzaman, Qing-Rong Chen, Chih Hao Hsu, Chunhua Yan, Cu Nguyen, Ying Hu, Charles G. Mullighan, Jing Ma, Lawrence J. Jennings, Ronald R. de Krijger, Marry M. van den Heuvel-Eibrink, Malcolm A. Smith, Nicole Ross, Julie M. Gastier-Foster, Elizabeth J. Perlman Oncotarget 6(18):15828-15841 (2015)
Molecular mechanisms in genetically defined autoinflammatory diseases: disorders of amplified danger signaling de Jesus AA, Canna SW, Liu Y, Goldbach-Mansky R. Annu Rev Immunol., doi: 10.1146/annurev-immunol-032414-112227 (2015)
Functional connectivity classification of autism identifies highly predictive brain features but falls short of biomarker standards Plitt M, Barnes KA, Martin A Neuroimage Clin., doi: 10.1016/j.nicl.2014.12.013. (2015)

Effects of the Mu opioid receptor polymorphism (OPRM1 A118G) on pain regulation, placebo effects and associated personality trait measures Peciña M, Love T, Stohler CS, Goldman D, Zubieta JK Neuropsychopharmacology, doi: 10.1038/npp.2014.272 (2015)
Calculation of Organ Doses for a Large Number of Patients Undergoing CT Examinations Amir Bahadori, Diana Miglioretti, Randell Kruger, Michael Flynn, Sheila Weinmann, Rebecca Smith-Bindman and Choonsik Lee Medical Physics and Informatics, DOI:10.2214/AJR.14.14135 (2015)
Survival of human lymphoma cells requires B-cell receptor engagement by self-antigens Ryan M. Young, Tianyi Wu, Roland Schmitz, Moez Dawood, Wenming Xiao, James D. Phelan, Weihong Xu, Laurence Menard, Eric Meffre, Wing-Chung C. Chan, Elaine S. Jaffe, Randy D. Gascoyne, Elìas Campo, Andreas Rosenwald, German Ott, Jan Delabie, Lisa M. Rimsza, and Louis M. Staudt PNAS, doi: 10.1073/pnas.1514944112 (2015)
Shifts in connectivity during procedural learning after motor cortex stimulation; a combined transcranial magnetic stimulation /functional magnetic resonance imaging study Adam Steel, Sunbin Song, Devin Bageac, Kristine M. Knutson, Ziad S. Saad, Stephen J. Gotts, Eric M. Wassermann, Leonora Wilkinson Cortex, doi:10.1016/j.cortex.2015.10.004 (2015)
Genome Sequences of Multidrug-Resistant Salmonella enterica Serovar Paratyphi B (dT+) and Heidelberg Strains from the Colombian Poultry Chain Pilar Donado-Godoy, Johan F. Bernal, Fernando Rodrìguez, Yolanda Gomez, Richa Agarwala, David Landsman, Leonardo Mariño-Ramìrez Genome Announc., doi: 10.1128/genomeA.01265-15 (2015)
The transcriptional landscape of age in human peripheral blood Peters, MJ; Joehanes, R; Pilling, LC et al. Nat Commun, DOI://10.1038/ncomms9570 (2015)

Empirical Optimization of Interactions between Proteins and Chemical Denaturants in Molecular Simulations Wenwei Zheng, Alessandro Borgia, Madeleine B. Borgia, Benjamin Schuler, and Robert B. Best J. Chem. Theory and Computation, DOI: 10.1021/acs.jctc.5b00778 (2015)
Characterization of the metastatic phenotype of a panel of established osteosarcoma cells Ren, L; Mendoza, A; Zhu, J et al. Oncotarget, DOI://10.18632/oncotarget.5177 (2015)
Computational Methods for Structural and Functional Studies of Alzheimer's Amyloid Ion Channels Hyunbum Jang, Fernando Teran Arce, Joon Lee, Alan L. Gillman, Srinivasan Ramachandran, Bruce L. Kagan, Ratnesh Lal, Ruth Nussinov Protein Amyloid Aggregation, doi://10.1007/978-1-4939-2978-8-16 (2015)
Single-cell RNA-Seq resolves cellular complexity in sensory organs from the neonatal inner ear Burns JC, Kelly MC, Hoa M, Morell RJ, Kelley MW Nature Communications, doi: 10.1038/ncomms9557. (2015)
Interleaved Text/Image Deep Mining on a Large-Scale Radiology Database for Automated Image Interpretation Hoo-Chang Shin, Le Lu, Lauren Kim, Ari Seff, Jianhua Yao, Ronald M. Summers IEEE CVPR , p. 1090-1099 (2015)
Longitudinal clinical trials with adaptive choice of follow-up time Jeffries N, Geller NL Biometrics, doi: 10.1111/biom.12287. E (2015)
Preparation and Crystallization of Riboswitches Alla Peselis, Ang Gao, Alexander Serganov Nucleic Acids Crystallography, doi://10.1007/978-1-4939-2763-0_3 (2015)
Effects of Neural Morphology and Input Distribution on Synaptic Processing by Global and Focal NMDA-Spikes Poleg-Polsky, A PLoS ONE, DOI://10.1371/journal.pone.0140254 (2015)
Dependence of negative-mode electrospray ionization response factors on mobile phase composition and molecular structure for newly-authenticated neutral acylsucrose metabolites Banibrata Ghosh and A. Daniel Jones Analyst, DOI: 10.1039/c4an02124j (2015)
Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumors Peter M. Moyle, Wei Dai, Tzu-Yu Liu, Waleed M. Hussein, Pirashanthini Maruthayanar, James W. Wells, Nigel A.J. McMillan, Mariusz Skwarczynski, Istvan Toth Bioorg. Med. Chem. Lett., doi:10.1016/j.bmcl.2015.10.049 (2015)
Establishment of Par-Polarized Cortical Domains via Phosphoregulated Membrane Motifs Matthew J. Bailey, Kenneth E. Prehoda Developmental Cell, doi://10.1016/j.devcel.2015.09.016 (2015)
Uncovering effects of antibiotics on the host and microbiota using transkingdom gene networks Morgun, A; Dzutsev, A; Dong, X et al. Gut, DOI://10.1136/gutjnl-2014-308820 (2015)

MST2-RASSF protein-protein interactions through SARAH domains Goar Sànchez-Sanz, David Matallanas, Lan K. Nguyen, Boris N. Kholodenko, Edina Rosta, Walter Kolch and Nicolae-Viorel Buchete Briefings in Bioinformatics, doi://10.1093/bib/bbv070 (2015)
Subassemblies and asymmetry in assembly of herpes simplex virus procapsid Aksyuk, AA; Newcomb, WW; Cheng, N et al. MBio, DOI://10.1128/mBio.01525-15 (2015)
GNL3 and SKA3 are novel prostate cancer metastasis susceptibility genes Minnkyong Lee, Kendra A. Williams, Ying Hu, Jonathan Andreas, Shashank J. Patel, Suiyuan Zhang, Nigel P. S. Crawford Clin Exp Metastasis, DOI 10.1007/s10585-015-9745-y (2015)
Putative Prostate Cancer Risk SNP in an Androgen Receptor-Binding Site of the Melanophilin Gene Illustrates Enrichment of Risk SNPs in Androgen Receptor Target Sites Huajie Bu, Narisu Narisu, Bettina Schlick, Johannes Rainer, Thomas Manke, Georg Schäfer, Lorenza Pasqualini, Peter Chines, Michal R. Schweiger, Christian Fuchsberger and Helmut Klocker Human Mutation, DOI: 10.1002/humu.22909 (2015)
Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity Hirahara K, Onodera A, Villarino AV, Bonelli M, Sciumè G, Laurence A3 Sun HW, Brooks SR, Vahedi, Shih HY, Gutierrez-Cruz, Iwata S, Suzuki, Mikami Y, Okamoto Y, Nakayama T, Holland SM, Hunter CA, Kanno Y, O'Shea JJ Immunity, doi: 10.1016/j.immuni.2015.04.014. (2015)
Efficient test for nonlinear dependence of two continuous variables Wang Y, Li Y, Cao H, Xiong M, Shugart YY, Jin L BMC Bioinformatics, doi: 10.1186/s12859-015-0697-7 (2015)

Whole-genome association analysis of treatment response in obsessive-compulsive disorder Qin H, Samuels JF, Wang Y et al. Mol. Psychiatr., doi: 10.1038/mp.2015.32 (2015)
The CENP-A N-tail confers epigenetic stability to centromeres via the CENP-T branch of the CCAN in fission yeast Folco HD, Campbell CS, May KM, Espinoza C, Oegema K, Hardwick KG, Grewal SI, Desai A Curr. Biology, doi: 10.1016/j.cub.2014.11.060 (2015)
RNA sequencing of the nephron transcriptome: A technical note Jae Wook Lee Kidney Research & Clinical Practice, doi:10.1016/j.krcp.2015.08.008 (2015)
Targeted Proteomics-Driven Computational Modeling of Macrophage S1P Chemosensing Manes, NP; Angermann, BR; Koppenol-Raab, M et al. Mol. Cell Proteomics, DOI://10.1074/mcp.M115.048918 (2015)
Genome-wide profiling of nucleosome sensitivity and chromatin accessibility in Drosophila melanogaster Razvan V. Chereji, Tsung-Wai Kan, Magda K. Grudniewska, Alexander V. Romashchenko, Eugene Berezikov, Igor F. Zhimulev, Victor Guryev, Alexandre V. Morozov and Yuri M. Moshkin Nucleic Acids Research, doi: 10.1093/nar/gkv978 (2015)
Identification of Scedosporium boydii catalase A1 gene, a reactive oxygen species detoxification factor highly expressed in response to oxidative stress and phagocytic cells Mina, Staerck et al Fungal Biology, doi:10.1016/j.funbio.2015.09.007 (2015)

Deep Proteomic Profiling of Vasopressin-Sensitive Collecting Duct Cells. II. Bioinformatic Analysis of Vasopressin Signaling Chin-Rang Yang, Viswanathan Raghuram, Milad Emamian, Pablo Concha Sandoval, Mark A. Knepper Am. J. Physiol. - Cell Physiol. , DOI: 10.1152/ajpcell.00214.2015 (2015)
Exposure of chick embryos to cadmium changes the extra-embryonic vascular branching pattern and alters expression of VEGF-A and VEGF-R2 Anna Kaskova Gheorghescu, Bartlomiej Tywoniuk, Johannes Duess, Nicolae-Viorel Buchete, Jennifer Thompson Toxicology & Applied Pharmacology, doi://10.1016/j.taap.2015.09.004 (2015)
Quantitative evaluation of positive φ angle propensity in flexible regions of proteins from three-bond J couplings Jung Ho Lee, Jinfa Ying and Ad Bax Phys. Chem. Chem. Phys., DOI: 10.1039/C5CP04542H (2015)
Turning Cucurbit[8]uril into a Supramolecular Nanoreactor for Asymmetric Catalysis Lifei Zheng, Silvia Sonzini, Masyitha Ambarwati, Edina Rosta, Oren A. Scherman and Andreas Herrmann Angewandte Chemie , DOI: 10.1002/anie.201505628 (2015)
Comparison against 186 canid whole-genome sequences reveals survival strategies of an ancient clonally transmissible canine tumor Brennan Decker, Brian W Davis, Maud Rimbault, Adrienne H Long, Eric Karlins, Heidi G Parker, Vidhya Jagannathan, Rebecca Reiman, Cord Drögemüller, Jason J Corneveaux, Erica S Chapman, Jeffery M Trent, Tosso Leeb, Matthew J Huentelman, Robert K Wayne, Danielle M Karyadi and Elaine A Ostrander Genome Research, doi: 10.1101/gr.190314.115 (2015)
Distinct profiles for mitochondrial t-RNAs and small nucleolar RNAs in locally invasive and metastatic colorectal cancer Lai Xu, Joseph Ziegelbauer, Rong Wang, Wells W Wu, Rong-Fong Shen, Hartmut H Juhl, Yaqin Zhang, and Amy S Rosenberg Clinical Cancer Research, doi: 10.1158/1078-0432.CCR-15-0737 (2015)

Plasma Levels of Soluble IL-2 Receptor α Associations With Clinical Cardiovascular Events and Genome-Wide Association Scan Peter Durda, Jeremy Sabourin, Ethan M. Lange, Mike A. Nalls, Josyf C. Mychaleckyj, Nancy Swords Jenny, Jin Li, Jeremy Walston, Tamara B. Harris, Bruce M. Psaty, William Valdar, Yongmei Liu, Mary Cushman, Alex P. Reiner, Russell P. Tracy, Leslie A. Lange Arteriosclerosis, Thrombosis and Vascular Biology, doi: 10.1161/ATVBAHA.115.305289 (2015)
Single Nucleotide Specific Targeting of the Tf1 Retrotransposon Promoted by the DNA-Binding Protein Sap1 of Schizosaccharomyces pombe Anthony Hickey, Caroline Esnault, Anasuya Majumdar, Atreyi Ghatak Chatterjee, James R. Iben, Philip G. McQueen, Andrew X. Yang, Takeshi Mizuguchi, Shiv I. S. Grewal and Henry L. Levin Genetics, doi: 10.1534/genetics.115.181602 (2015)
Pressure-induced structural transition of mature HIV-1 Protease from a combined NMR/MD simulation approach Julien Roche, John M. Louis, Ad Bax and Robert B. Best Proteins, DOI: 10.1002/prot.24931 (2015)
Histone H3 Lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiation Sugata Manna, Jong Kyong Kim, Catherine Baugé, Margaret Cam, Yongmei Zhao, Jyoti Shetty, Melanie S. Vacchio, Ehydel Castro, Bao Tran, Lino Tessarollo & Rémy Bosselut Nature Communications, doi:10.1038/ncomms9152 (2015)
Tautomerism of Warfarin: Combined Chemoinformatics, Quantum Chemical, and NMR Investigation Laura Guasch, Megan L. Peach, and Marc C Nicklaus J. Org. Chem. , DOI: 10.1021/acs.joc.5b01370 (2015)
Comparative analyses of CTCF and BORIS occupancies uncover two distinct classes of CTCF binding genomic regions Elena M. Pugacheva, Samuel Rivero-Hinojosa, Celso A. Espinoza, et al. Genome Biol. , doi: 10.1186/s13059-015-0736-8 (2015)

Triangulating the sexually dimorphic brain through high-resolution neuroimaging of murine sex chromosome aneuploidies Raznahan, A; Lue, Y; Probst, F et al. Brain Struct Funct, DOI://10.1007/s00429-014-0875-9 (2015)
TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow Yang, Q; Li, F; Harly, C et al. Nat. Immunol., DOI://10.1038/ni.3248 (2015)
Assessing FOXO1A as a potential susceptibility locus for type 2 diabetes and obesity in American Indians Yunhua L. Muller, Robert L. Hanson, Gregory Wiessner, Lori Nieboer, Sayuko Kobes, Paolo Piaggi, Mahdi Abdussamad, Chidinma Okani, William C. Knowler, Clifton Bogardus andLeslie J. Baier Obesity, DOI: 10.1002/oby.21236 (2015)
Correlation of magnetic resonance imaging with digital histopathology in prostate Jin Tae Kwak, Sandeep Sankineni, Sheng Xu, Baris Turkbey, Peter L. Choyke, Peter A. Pinto, Maria Merino, Bradford J. Wood Int. J. CARS, DOI 10.1007/s11548-015-1287-x (2015)
Novel Human-like Influenza A Viruses Circulate in Swine in Mexico and Chile Martha Nelson, Marie R. Culhane, Albert Rovira, Montserrat Torremorell, Pedro Guerrero, and Julio Norambuena PLoS Currents, doi: 10.1371/currents.outbreaks.c8b3207c9bad98474eca3013fa933ca6 (2015)
Defining the Domain Arrangement of the Mammalian Target of Rapamycin Complex Component Rictor Protein Zhou P, Zhang N, Nussinov R, Ma B J. Comput. Biol., DOI://10.1089/cmb.2015.0103 (2015)

Three dysconnectivity patterns in treatment-resistant schizophrenia patients and their unaffected siblings Wang J, Cao H, Liao Y et al. Neuroimage Clin. , doi: 10.1016/j.nicl.2015.03.017 (2015)
The jigsaw puzzle of sequence phenotype inference: Piecing together Shannon entropy, importance sampling, and Empirical Bayes Shreif Z, Striegel DA, Periwal V J. Theoretical Biology, doi: 10.1016/j.jtbi.2015.06.010. (2015)
A Deep Insight Into the Sialotranscriptome of the Chagas Disease Vector, Panstrongylus megistus (Hemiptera: Heteroptera) Ribeiro JM, Schwarz A, Francischetti IM J. Med. Entomol., DOI://10.1093/jme/tjv023 (2015)
Deep Proteomic Profiling of Vasopressin-Sensitive Collecting Duct Cells. I. Virtual Western Blots and Molecular Weight Distributions Chin-Rang Yang, Pumipat Tongyoo, Milad Emamian, Pablo Concha Sandoval, Viswanathan Raghuram, Mark A. Knepper Am. J. Physiol. - Cell Physiol. , DOI: 10.1152/ajpcell.00213.2015 (2015)
Impact of conscious intent on chunking during motor learning Sunbin Song and Leonardo Cohen Learning & Memory, doi: 10.1101/lm.035824.114 (2015)
Small Retinoprotective Peptides Reveal a Receptor-binding Region on Pigment Epithelium-derived Factor Jason Kenealey, Preeti Subramanian, Antonella Comitato, Jeanee Bullock, Laura Keehan, Federica Polato, David Hoover, Valeria Marigo and S. Patricia Becerra J. Biol. Chem. , doi: 10.1074/jbc.M115.645846 (2015)

Amylin-Aβ oligomers at atomic resolution using molecular dynamics simulations: a link between Type 2 diabetes and Alzheimer's disease Michal Baram , Yoav Atsmon-Raz , Buyong Ma , Ruth Nussinov and Yifat Miller Phys. Chem. Chem. Phys., DOI: 10.1039/C5CP03338A (2015)
A Bayesian joint model of menstrual cycle length and fecundity Kirsten J. Lum, Rajeshwari Sundaram, Germaine M. Buck Louis andThomas A. Louis Biometrics, DOI: 10.1111/biom.12379 (2015)
Revealing the fate of cell surface human P-glycoprotein (ABCB1): The lysosomal degradation pathway Katayama, K; Kapoor, K; Ohnuma, S et al. Biochim. Biophys. Acta, DOI://10.1016/j.bbamcr.2015.06.001 (2015)
An Improved F(st) Estimator Chen, G; Yuan, A; Shriner, D et al. PLoS ONE, DOI://10.1371/journal.pone.0135368 (2015)
Genome-wide association study of neocortical Lewy-related pathology Terhi Peuralinna, Liisa Myllykangas, Minna Oinas,, Mike A. Nalls, Hannah A. D. Keage, Veli-Matti Isoviita, Miko Valori, Tuomo Polvikoski, Anders Paetau, Raimo Sulkava, Paul G. Ince, Julia Zaccai, Carol Brayne, Bryan J. Traynor, John Hardy, Andrew B. Singleton and Pentti J. Tienari Annalls of Clinical and Translational Neurology, DOI: 10.1002/acn3.231 (2015)
Confusing placebo effect with natural history in epilepsy: A big data approach Goldenholz DM, Moss R, Scott J, Auh S, Theodore WH Ann. Neurol., DOI://10.1002/ana.24470 (2015)

Possible Human Papillomavirus 38 Contamination of Endometrial Cancer RNA Sequencing Samples in The Cancer Genome Atlas Database Majid Kazemian, Min Ren, Jian-Xin Lin, Wei Liao, Rosanne Spolski and Warren J. Leonard J. Virology, doi: 10.1128/JVI.00822-15 (2015)
The Beta Cell in Its Cluster: Stochastic Graphs of Beta Cell Connectivity in the Islets of Langerhans Deborah A. Striegel, Manami Hara, Vipul Periwal PLoS Computational Biology, DOI: 10.1371/journal.pcbi.1004423 (2015)
Baseline genetic associations in the Parkinson's Progression Markers Initiative (PPMI) Mike A. Nalls, Margaux F. Keller, Dena G. Hernandez, Lan Chen, David J. Stone , Andrew B. Singleton, andon behalf of the Parkinson's Progression Marker Initiative (PPMI) investigators Movement Disorders, DOI: 10.1002/mds.26374 (2015)
Presenilin 1 Maintains Lysosomal Ca2+ Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification Ju-Hyun Lee, Mary Kate McBrayer, Devin M. Wolfe, Luke J. Haslett, Asok Kumar, Yutaka Sato, Pearl P.Y. Lie, Panaiyur Mohan, Erin E. Coffey, Uday Kompella, Claire H. Mitchell, Emyr Lloyd-Evans, Ralph A. Nixon Cell Reports , doi:10.1016/j.celrep.2015.07.050 (2015)
Modeling ligand recognition at the P2Y12 receptor in light of X-ray structural information Paoletta, S; Sabbadin, D; von Kügelgen, I et al. J. Comput. Aided Mol. Des., DOI://10.1007/s10822-015-9858-z (2015)
Gα13 Stimulates the Tyrosine Phosphorylation of Ric-8A Mingda Yan, Ji Ha, Danny Dhanasekaran J. Molecular Signaling, doi://10.5334/1750-2187-10-3 (2015)

Molecular structure of monomorphic peptide fibrils within a kinetically trapped hydrogel network Katelyn Nagy-Smith, Eric Moore, Joel Schneider, and Robert Tycko PNAS, doi: 10.1073/pnas.1509313112 (2015)
Divergence from the classical hydroboration reactivity; boron containing materials through a hydroboration cascade of small cyclic dienes Anna Andreou, Michal Leskes, Pablo G. Jambrina, Gary J. Tustin, Clare P. Grey, Edina Rosta, and Oren A. Scherman Chemical Science, DOI: 10.1039/b000000x (2015)
ABCC8 R1420H loss-of-function variant in a Southwest American Indian community: association with increased birth weight and doubled risk of type 2 diabetes Leslie J. Baier, Yunhua Li Muller, Maria Sara Remedi, Michael Traurig, Paolo Piaggi, Gregory Wiessner, Ke Huang, Alyssa Stacy, Sayuko Kobes, Jonathan Krakoff, Peter H. Bennett, Robert G. Nelson, William C. Knowler, Robert L. Hanson, Colin G. Nichols and Clifton Bogardus Diabetes, doi: 10.2337/db15-0459 (2015)
Comprehensive assembly of novel transcripts from unmapped human RNA-Seq data and their association with cancer Majid Kazemian, Min Ren, Jian‐Xin Lin, Wei Liao, Rosanne Spolski, Warren J Leonard Molecular Systems Biology, DOI 10.15252/msb.156172 (2015)
A β Stretching-and-Packing Cross-Seeding Mechanism Can Trigger Tau Protein Aggregation Ruxi Qi, Yin Luo, Guanghong Wei, Ruth Nussinov, and Buyong Ma J. Phys. Chem Letters, DOI: 10.1021/acs.jpclett.5b01447 (2015)
Membrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory Zoe Cournia, Toby W. Allen et al. J. Membrane Biology, DOI: 10.1007/s00232-015-9802-0 (2015)

Mechanical properties of lipid bilayers from molecular dynamics simulation Richard M. Venable, Frank L.H. Brown, Richard W. Pastor Chemistry and Physics of Lipids, doi:10.1016/j.chemphyslip.2015.07.014 (2015)
Runx1 is required for hematopoietic defects and leukemogenesis in Cbfb-MYH11 knock-in mice Hyde RK, Zhao L, Alemu L, Liu PP Leukemia, DOI://10.1038/leu.2015.58 (2015)
PTH and Vitamin D Repress DMP1 in Cementoblasts Wang L, Tran AB, Nociti FH Jr, Thumbigere-Math V, Foster BL, Krieger CC, Kantovitz KR, Novince CM, Koh AJ, McCauley LK, Somerman MJ J Dent Res. , doi: 10.1177/0022034515599726 (2015)
4'-modified nucleoside analogs: Potent inhibitors active against entecavir-resistant hepatitis B virus Takamatsu Y, Tanaka Y, Kohgo S,, Murakami S, Singh K, Das D, Venzon DJ, Amano M, Higashi-Kuwata N, Aoki M, Delino NS, Hayashi S, Takahashi S, Sukenaga Y, Haraguchi K, Sarafianos SG, Maeda K, Mitsuya H Hepatology, doi: 10.1002/hep.27962 (2015)
Super-enhancers: Asset management in immune cell genomes Steven Witte, John J. O'Shea, Golnaz Vahedi Trends in Immunology, doi: 10.1016/j.it.2015.07.005. (2015)
Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection Hadi M Yassine, Jeffrey C Boyington, Patrick M McTamney, Chih-Jen Wei, Masaru Kanekiyo, Wing-Pui Kong, John R Gallagher, Lingshu Wang, Yi Zhang, M Gordon Joyce, Daniel Lingwood, Syed M Moin, Hanne Andersen, Yoshinobu Okuno, Srinivas S Rao, Audray K Harris, Peter D Kwong, John R Mascola, Gary J Nabel & Barney S Graham Nature Medicine, doi:10.1038/nm.3927 (2015)

Mapsnp: an R package to plot a genomic map for single nucleotide polymorphisms Zhang F, Xu Y, Cao H, Jin C, Cheng Z, Wang G, Shugart YY PLoS One, doi: 10.1371/journal.pone.0123609 (2015)
Distinct transcriptome profiles differentiate nonsteroidal anti-inflammatory drug-dependent from nonsteroidal anti-inflammatory drug-independent food-induced anaphylaxis Muñoz-Cano R, Pascal M, Bartra J, Picado C, Valero A, Kim DK, Brooks S, Ombrello M, Metcalfe DD, Rivera J, Olivera A J Allergy Clin Immunol. , doi: 10.1016/j.jaci.2015.05.042. (2015)
Resting state connectivity of the bed nucleus of the stria terminalis at ultra-high field Salvatore Torrisi, Katherine O'Connell, Andrew Davis, Richard Reynolds, Nicholas Balderston, Julie Fudge, Christian Grillon and Monique Ernst Human Brain Mapping, DOI: 10.1002/hbm.22899 (2015)
Metabolic mapping of A3 adenosine receptor agonist MRS5980 Fang ZZ, Tosh DK, Tanaka N, Wang H, Krausz KW, O'Connor R, Jacobson KA, Gonzalez FJ Biochem Pharmacol., doi: 10.1016/j.bcp.2015.07.007. (2015)
RAG Represents a Widespread Threat to the Lymphocyte Genome Grace Teng, Yaakov Maman, Wolfgang Resch, Min Kim, Arito Yamane, Jason Qian, Kyong-Rim Kieffer-Kwon, Malay Mandal, Yanhong Ji, Eric Meffre, Marcus R. Clark, Lindsay G. Cowell, Rafael Casellas, David G. Schatz Cell, doi:10.1016/j.cell.2015.07.009 (2015)
Variation in the Williams syndrome GTF2I gene and anxiety proneness interactively affect prefrontal cortical response to aversive stimuli Jabbi M, Chen Q, Turner N, Kohn P, White M, Kippenhan JS, Dickinson D, Kolachana B, Mattay V, Weinberger DR, Berman KF Transl Psychiatry., doi: 10.1038/tp.2015.98. (2015)
Improved Expression and Characterization of a Multidomain Xylanase from Thermoanaerobacterium aotearoense SCUT27 in Bacillus subtilis Xiongliang Huang, Zhe Li, Chenyu Du, Jufang Wang, and Shuang Li J. Agric. Food Chem., DOI: 10.1021/acs.jafc.5b01259 (2015)
Areas of Brain Damage Underlying Increased Reports of Behavioral Disinhibition Knutson, KM; Dal Monte, O; Schintu, S et al. J Neuropsychiatry Clin Neurosci, DOI://10.1176/appi.neuropsych.14060126 (2015)
Opposing roles of STAT1 and STAT3 in IL-21 function in CD4+ T cells Wan, CK; Andraski, AB; Spolski, R et al. Proc. Natl. Acad. Sci. U.S.A., DOI://10.1073/pnas.1511711112 (2015)
Gene-Gene Interaction Among WNT Genes for Oral Cleft in Trios Li Q, Kim Y, Suktitipat B, Hetmanski JB, Marazita ML, Duggal P, Beaty TH, Bailey-Wilson JE Genet Epidemiol., doi: 10.1002/gepi.21888. (2015)
Convergent BOLD and Beta-Band Activity in Superior Temporal Sulcus and Frontolimbic Circuitry Underpins Human Emotion Cognition Jabbi M, Kohn PD, Nash T, Ianni A, Coutlee C, Holroyd T, Carver FW, Chen Q, Cropp B, Kippenhan JS, Robinson SE, Coppola R, Berman KF Cerebral Cortex, doi: 10.1093/cercor/bht427. (2015)
An Integrative Genomic Study Implicates the Post-Synaptic Density in the Pathogenesis of Bipolar Disorder Akula N, Wendland JR, Choi KH, McMahon FJ Neuropsychopharmacology, doi: 10.1038/npp.2015.218 (2015)

A mutation of MET, encoding hepatocyte growth factor receptor, is associated with human DFNB97 hearing loss Mujtaba G, Schultz JM, Imtiaz A, Morell RJ, Friedman TB, Naz S J. Med. Genet., DOI://10.1136/jmedgenet-2015-103023 (2015)
Directional dominance on stature and cognition in diverse human populations Joshi, PK; Esko, T; Mattsson, H et al. Nature, DOI://10.1038/nature14618 (2015)
A two-state mixed hidden Markov model for risky teenage driving behavior John C. Jackson, Paul S. Albert, and Zhiwei Zhang Ann. Appl. Stat., doi:10.1214/14-AOAS765 (2015)
Women Workers and Women at Home Are Equally Inactive: NHANES 2003-2006 Steeves JA, Murphy RA, Zipunnikov V, Strath SJ, Harris TB Med Sci Sports Exerc, DOI://10.1249/MSS.0000000000000582 (2015)
Novel genomic signals of recent selection in an Ethiopian population Tekola-Ayele, F; Adeyemo, A; Chen, G et al. Eur. J. Hum. Genet., DOI://10.1038/ejhg.2014.233 (2015)
Genome Analysis of Latin American Cervical Cancer: Frequent Activation of the PIK3CA Pathway Hong Lou, Guillermo Villagran, Joseph F. Boland, Kate M Im, Sarita Polo, Weiyin Zhou, Ushie Odey, Eligia Juàrez-Torres, Ingrid Medina-Martìnez, Edgar Roman-Basaure, Jason Mitchell, David Roberson, Julie Sawitzke, Lisa Garland, Maria Rodrìguez-Herrera, David Wells, Jennifer Troyer, Francisco Castillo, Sara Bass, Xijun Zhang, Miriam Castillo, Bert Gold, Hesler Morales, Meredith Yeager, Jaime Berumen, Enrique Alvirez, Eduardo Gharzouzi, and Michael Dean Clinical Cancer Research, doi:10.1158/1078-0432.CCR-14-1837 (2015)

Classification of occupational activity categories using accelerometry: NHANES 2003-2004 Steeves JA, Tudor-Locke C, Murphy RA, King GA, Fitzhugh EC, Harris TB Int J Behav Nutr Phys Act, DOI://10.1186/s12966-015-0235-z (2015)
Bolaamphiphiles as Carriers for siRNA Delivery: From Chemical Syntheses to Practical Applications Kshitij Gupta, Kirill A. Afonin, Mathias Viarda, Virginia Herrero, Wojciech Kasprzak, Ioannis Kagiampakis, Taejin Kim, Alexey Y. Koyfman, Anu Puri, Marissa Stepler, Alison Sappe, Vineet N. KewalRamani, Sarina Grinberg, Charles Linder, Eliahu Heldman, Robert Blumenthal, Bruce A. Shapiro J. Controlled Release, doi:10.1016/j.jconrel.2015.06.041 (2015)
MitoRCA-seq reveals unbalanced cytocine to thymine transition in Polg mutant mice Ni T, Wei G, Shen T, Han M, Lian Y, Fu H, Luo Y, Yang Y, Liu J, Wakabayashi Y, Li Z, Finkel T, Xu H, Zhu J Scientific Reports, doi: 10.1038/srep12049. (2015)
Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci Demerath, EW; Guan, W; Grove, ML et al. Hum. Mol. Genet., DOI://10.1093/hmg/ddv161 (2015)
A Systems Level Analysis of Vasopressin-mediated Signaling Networks in Kidney Distal Convoluted Tubule Cells Lei Cheng, Qi Wu, Marleen L. A. Kortenoeven, Trairak Pisitkun, Robert A. Fenton Sci. Rep. , doi: 10.1038/srep12829 (2015)
Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations Sonia Shah, Marc J. Bonder, Riccardo E. Marioni et al. Am. J. Hum. Genet. , doi:/10.1016/j.ajhg.2015.05.014 (2015)

2.2 Å resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor Alberto Bartesaghi, Alan Merk, Soojay Banerjee, Doreen Matthies, Xiongwu Wu, Jacqueline L. S. Milne, Sriram Subramaniam Science, DOI: 10.1126/science.aab1576 (2015)
miR-23a impairs bone differentiation in osteosarcoma via down-regulation of GJA1 Gindin Y, Jiang Y, Francis P, Walker RL, Abaan OD, Zhu YJ, Meltzer PS Front Genet. , doi: 10.3389/fgene.2015.00233 (2015)
Motif signatures in stretch enhancers are enriched for disease-associated genetic variants Daniel X Quang, Michael R Erdos, Stephen C J Parker,and Francis S Collins Epigenetics Chromatin, doi: 10.1186/s13072-015-0015-7. (2015)
Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools Ding J, Sidore C, Butler TJ, Wing MK, Qian Y, Meirelles O, Busonero F, Tsoi LC, Maschio A, Angius A, Kang HM, Nagaraja R, Cucca F, Abecasis GR, Schlessinger D PLoS Genetics, doi: 10.1371/journal.pgen.1005306 (2015)
EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion Yang XP, Jiang K, Hirahara K, Vahedi G, Afzali B, Sciume G, Bonelli M, Sun HW, Jankovic D, Kanno Y, Sartorelli V, O'Shea JJ, Laurence A Scientific Reports, doi: 10.1038/srep10643 (2015)
Recurrent Mutations in the Basic Domain of TWIST2 Cause Ablepharon Macrostomia and Barber-Say Syndromes Marchegiani, S; Davis, T; Tessadori, F et al. Am. J. Hum. Genet., DOI://10.1016/j.ajhg.2015.05.017 (2015)

An Insight into the Sialome of the Lone Star Tick, Amblyomma americanum, with a Glimpse on Its Time Dependent Gene Expression Karim S, Ribeiro JM PLoS ONE, DOI://10.1371/journal.pone.0131292 (2015)
Positing, fitting, and selecting regression models for pooled biomarker data Mitchell EM, Lyles RH, Schisterman EF Stat Med, DOI://10.1002/sim.6496 (2015)
Metabolic Regulation of Histone Acetyltransferases by Endogenous Acyl-CoA Cofactors Montgomery DC, Sorum AW, Guasch L, Nicklaus MC, Meier JL Chem Biol., doi: 10.1016/j.chembiol.2015.06.015. (2015)
Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder , ; de Moor, MH; van den Berg, SM et al. JAMA Psychiatry, DOI://10.1001/jamapsychiatry.2015.0554 (2015)
RNA-Seq analysis of high NaCl-induced gene expression Izumi Y, Yang W, Zhu J, Burg MB, Ferraris JD Physiol Genomics., doi: 10.1152/physiolgenomics.00057.2015 (2015)
Transcriptome dynamics of developing photoreceptors in three-dimensional retina cultures recapitulates temporal sequence of human cone and rod differentiation revealing cell surface markers and gene networks Kaewkhaw R, Kaya KD, Brooks M, Homma K, Zou J, Chaitankar V, Rao M, Swaroop A Stem Cells, doi: 10.1002/stem.2122. (2015)

Dietary fatty acids modulate associations between genetic variants and circulating fatty acids in plasma and erythrocyte membranes: Meta-analysis of nine studies in the CHARGE consortium Smith, CE; Follis, JL; Nettleton, JA et al. Mol Nutr Food Res, DOI://10.1002/mnfr.201400734 (2015)
GTP-Dependent K-Ras Dimerization Muratcioglu S, Chavan TS, Freed BC, Jang H, Khavrutskii L, Freed RN, Dyba MA, Stefanisko K, Tarasov SG, Gursoy A, Keskin O, Tarasova NI, Gaponenko V, Nussinov R Structure, doi: 10.1016/j.str.2015.04.019 (2015)
New monogenic autoinflammatory diseases--a clinical overview Canna SW, Goldbach-Mansky R Semin Immunopathol. , doi: 10.1007/s00281-015-0493-5 (2015)
Tracking ongoing cognition in individuals using brief, whole-brain functional connectivity patterns Javier Gonzalez-Castillo, Colin W. Hoy, Daniel A. Handwerker, Meghan E. Robinson, Laura C. Buchanan, Ziad S. Saad, and Peter A. Bandettini PNAS, doi: 10.1073/pnas.1501242112 (2015)
Forgetting the best when predicting the worst: Preliminary observations on neural circuit function in adolescent social anxiety Jarcho JM, Romer AL, Shechner T, Galvan A, Guyer AE, Leibenluft E, Pine DS, Nelson EE Dev Cogn Neurosci. , doi: 10.1016/j.dcn.2015.03.002 (2015)
Influenza A Viruses of Human Origin in Swine, Brazil Martha I. Nelson , Rejane Schaefer, Danielle Gava, Maurìcio Egĩdio Cantão, and Janice Reis Ciacci-Zanella Emerg Infect Dis. , doi://10.3201/eid2108.141891 (2015)

Acute and recent air pollution exposure and cardiovascular events at labour and delivery Tuija Männistö, Pauline Mendola, Katherine Laughon Grantz, Kira Leishear, Rajeshwari Sundaram, Seth Sherman, Qi Ying, Danping Liu Heart, doi:10.1136/heartjnl-2014-307366 (2015)
Proteomic analysis of the kidney filtration barrier�Problems and perspectives Markus M. Rinschen Thomas Benzing, Kavee Limbutara and Trairak Pisitkun Proteomics Clinical Applications, DOI: 10.1002/prca.201400201 (2015)
Homologous Mutation to Human BRAF V600E Is Common in Naturally Occurring Canine Bladder Cancer--Evidence for a Relevant Model System and Urine-Based Diagnostic Test Decker B, Parker HG, Dhawan D, Kwon EM, Karlins E, Davis BW, Ramos-Vara JA, Bonney PL, McNiel EA, Knapp DW, Ostrander EA Mol Cancer Res, doi: 10.1158/1541-7786.MCR-14-0689 (2015)
Nucleosome adaptability conferred by sequence and structural variations in histone H2A-H2B dimers Shaytan AK, Landsman D, Panchenko AR Curr Opin Struct Biol., doi: 10.1016/j.sbi.2015.02.004 (2015)
Possible HPV38 contamination of endometrial cancer RNA-Seq samples in The Cancer Genome Atlas database Majid Kazemian, Min Ren, Jian-Xin Lin, Wei Liao, Rosanne Spolski and Warren J. Leonard J. Virology, doi: 10.1128/JVI.00822-15 (2015)
Coupling of Zinc-Binding and Secondary Structure in Nonfibrillar Aβ40 Peptide Oligomerization Xu L, Shan S, Chen Y, Wang X, Nussinov R, Ma B J Chem Inf Model, DOI://10.1021/acs.jcim.5b00063 (2015)

Assessment of Cancer Cell Line Representativeness Using Microarrays for Merkel Cell Carcinoma Kenneth Daily, Amy Coxon, Jonathan S Williams, Chyi-Chia R Lee, Daniel G Coit, Klaus J Busam and Isaac Brownell J. Investigative Dermatology, doi:10.1038/jid.2014.518 (2015)
Shared genetic basis for migraine and ischemic stroke Rainer Malik, Tobias Freilinger et al. Neurology, doi: 10.1212/WNL.0000000000001606 (2015)
Quantitative Interpretation of FRET Experiments via Molecular Simulation: Force Field and Validation Robert B. Best, Hagen Hofmann, Daniel Nettell, Benjamin Schuler Biochemistry, doi:10.1016/j.bpj.2015.04.038 (2015)
DNA methylome and transcriptome sequencing in human ovarian granulosa cells links age-related changes in gene expression to gene body methylation and 3'-end GC density Yu B, Russanova VR, Gravina S, Hartley S, Mullikin JC, Ignezweski A6 Graham J, Segars JH, DeCherney AH, Howard BH Oncotarget, 6(6): 3627-3643. (2015)
Gene Level Meta-Analysis of Quantitative Traits by Functional Linear Models Ruzong Fan, Yifan Wang, Michael Boehnke, Wei Chen, Yun Li, Haobo Ren, Iryna Lobach and Momiao Xiong Genetics, doi: 10.1534/genetics.115.178343 (2015)
Homology modeling of larger proteins guided by chemical shifts Yang Shen & Ad Bax Nature Methods, doi:10.1038/nmeth.3437 (2015)

Conformational processing of oncogenic v-Src kinase by the molecular chaperone Hsp90 Edgar E. Boczek , Lasse G. Reefschläger, Marco Dehling, Tobias J. Struller , Elisabeth Häusler , Andreas Seidl , Ville R. I. Kaila , and Johannes Buchner PNAS, doi: 10.1073/pnas.1424342112 (2015)
Insertion Sequence IS26 Reorganizes Plasmids in Clinically Isolated Multidrug-Resistant Bacteria by Replicative Transposition He, S; Hickman, AB; Varani, AM et al. MBio, DOI://10.1128/mBio.00762-15 (2015)
Etiologic Ischemic Stroke Phenotypes in the NINDS Stroke Genetics Network Hakan Ay, Ethem Murat Arsava, Gunnar Andsberg et al. Stroke, doi: 10.1161/STROKEAHA.114.007362 (2015)
Identification of microRNAs specific for epithelial cell adhesion molecule�positive tumor cells in hepatocellular carcinoma Junfang Ji, Xin Zheng, Marshonna Forgues, Taro Yamashita, Eliane L. Wauthier, Lola M. Reid, Xinyu Wen, Young Song, Jun S. Wei, Javed Khan, Snorri S. Thorgeirsson andXin Wei Wang Hepatology, doi: 10.1002/hep.27886. (2015)
High-level expression of human arginase I in Pichia pastoris and its immobilization on chitosan to produce L-ornithine Xue Zhang, Jin Liu, Xianhong Yu, Fei Wang, Li Yi, Zhezhe Li, Yunyun Liu, and Lixin Macorresponding author BMC Biotechnol. , doi: 10.1186/s12896-015-0184-2 (2015)
Expression and Characterization of the RKOD DNA Polymerase in Pichia pastoris Fei Wang, Shuntang Li, Hui Zhao, Lu Bian, Liang Chen, Zhen Zhang, Xing Zhong, Lixin Ma, Xiaolan Yu PLoS One, doi: 10.1371/journal.pone.0131757 (2015)

Model-free functional connectivity and impulsivity correlates of alcohol dependence: a resting-state study Zhu X, Cortes CR, Mathur K, Tomasi D, Momenan R Addict Biol. , doi: 10.1111/adb.12272 (2015)
Pretreatment Differences in BOLD Response to Emotional Faces Correlate with Antidepressant Response to Scopolamine Furey ML, Drevets WC, Szczepanik J, Khanna A, Nugent A, Zarate CA Int. J. Neuropsychopharmacol., DOI://10.1093/ijnp/pyv028 (2015)
Sliding Motility, Biofilm Formation, and Glycopeptidolipid Production in Mycobacterium colombiense Strains Maya-Hoyos M, Leguizam�n J, Mari�o-Ram�rez L, Soto CY Biomed Res Int. , doi: 10.1155/2015/419549 (2015)
Gene expression markers of age-related inflammation in two human cohorts Pilling LC, Joehanes R, Melzer D, Harries LW, Henley W, Dupuis J, Lin H, Mitchell M, Hernandez D, Ying SX, Lunetta KL, Benjamin EJ, Singleton A, Levy D, Munson P, Murabito JM, Ferrucci L Exp Gerontol. , doi: 10.1016/j.exger.2015.05.012 (2015)
The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence P Suchankova, J Yan, M L Schwandt, B L Stangl, E C Caparelli, R Momenan, E Jerlhag, J A Engel, C A Hodgkinson, M Egli, M F Lopez, H C Becker, D Goldman, M Heilig, V A Ramchandani, and L Leggio Transl Psychiatry. , doi: 10.1038/tp.2015.68 (2015)
Topological polymorphism of the two-start chromatin fiber Norouzi D, Zhurkin VB Biophys. J., doi: 10.1016/j.bpj.2015.04.015 (2015)

A genome-wide association study of suicidal behavior Galfalvy H, Haghighi F, Hodgkinson C, Goldman D, Oquendo MA, Burke A, Huang YY, Giegling I, Rujescu D, Bureau A, Turecki G, Mann JJ Am J Med Genet B Neuropsychiatr Genet. , doi: 10.1002/ajmg.b.32330 (2015)
Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors Zhou T, Lynch RM, Chen L et al. Cell, doi: 10.1016/j.cell.2015.05.007 (2015)
Group Differences in MEG-ICA Derived Resting State Networks: Application to Major Depressive Disorder Allison C. Nugent, Stephen E. Robinson, Richard Coppola, Maura L. Furey, Carlos A. Zarate Jr NeuroImage, doi:10.1016/j.neuroimage.2015.05.051 (2015)
APOL1 G1 genotype modifies the association between HDLC and kidney function in African Americans Bentley, AR; Divers, J; Shriner, D et al. BMC Genomics, DOI://10.1186/s12864-015-1645-7 (2015)
A liver-enriched long non-coding RNA, lncLSTR, regulates systemic lipid metabolism in mice Li P, Ruan X, Yang L, Kiesewetter K, Zhao Y, Luo H, Chen Y, Gucek M, Zhu J, Cao H Cell Metabolism, doi: 10.1016/j.cmet.2015.02.004 (2015)
24, 25-Dihydroxyvitamin D 3 and Vitamin D Status of Community-Dwelling Black and White Americans Anders H. Berg, Camille E. Powe, Michele K. Evans, Julia Wenger, Guillermo Ortiz, Alan B. Zonderman, Pirianthini Suntharalingam, Kathryn Lucchesi, Neil R. Powe, S. Ananth Karumanchi, and Ravi I. Thadhani Clinical Chemistry, doi:10.1373/clinchem.2015.240051 (2015)

A cis-eQTL in PFKFB2 is associated with diabetic nephropathy, adiposity and insulin secretion in American Indians Muller YL, Piaggi P, Hanson RL, Kobes S, Bhutta S, Abdussamad M, Leak-Johnson T, Kretzler M, Huang , Weil EJ, Nelson RG, Knowler WC, Bogardus C, Baier LJ Hum Mol Genet. , doi: 10.1093/hmg/ddv040 (2015)
Endoplasmic reticulum-associated amino-peptidase 1 and rheumatic disease: genetics Ombrello MJ, Kastner DL, Remmers EF Curr Opin Rheumatol, DOI://10.1097/BOR.0000000000000189 (2015)
Converging evidence implicates the abnormal microRNA system in schizophrenia. Zhang F, Xu Y, Shugart YY, Yue W, Qi G, Yuan G, Cheng Z, Yao J, Wang J, Wang G, Cao H, Guo W, Zhou Z, Wang Z, Tian L, Jin C, Yuan J, Liu C, Zhang D Schizophrenia Bulletin, doi: 10.1093/schbul/sbu (2015)
Confirmation of genetic variants associated with lethal prostate cancer in a cohort of men from hereditary prostate cancer families Karyadi DM, Zhao S, He Q, McIntosh L, Wright JL, Ostrander EA, Feng Z, Stanford JL. Int. J. Cancer, doi: 10.1002/ijc.29241 (2015)
Baseline working memory activation deficits in dimensional anxious depression as detected by magnetoencephalography Ionescu, DF; Nugent, AC; Luckenbaugh, DA et al. Acta Neuropsychiatr, DOI://10.1017/neu.2014.46 (2015)
Mutation-targeted therapy with sunitinib or everolimus in patients with advanced low-grade or intermediate-grade neuroendocrine tumours of the gastrointestinal tract and pancreas with or without cytoreductive surgery: protocol for a phase II clinical trial Neychev, V; Steinberg, SM; Cottle-Delisle, C et al. BMJ Open, DOI://10.1136/bmjopen-2015-008248 (2015)

Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project Paul L. Auer, Mike Nalls, James F. Meschia, et al. JAMA Neurology, doi:10.1001/jamaneurol.2015.0582 (2015)
Aβ(1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease Yiling Xiao, Buyong Ma, Dan McElheny, Sudhakar Parthasarathy, Fei Long, Minako Hoshi, Ruth Nussinov & Yoshitaka Ishii Nat Struct Mol Biol, doi:10.1038/nsmb.2991 (2015)
Infrared, Raman, and Ultraviolet Absorption Spectra and Theoretical Calculations and Structure of 2,3,5,6-Tetrafluoropyridine in its Ground and Excited Electronic States Hong-Li Sheu, Praveenkumar Boopalachandran, Sunghwan Kim, Jaan Laane Chemical Physics, doi:10.1016/j.chemphys.2015.04.011 (2015)
PAPST, a User Friendly and Powerful Java Platform for ChIP-Seq Peak Co-Localization Analysis and Beyond Paul W. Bible , Yuka Kanno, Lai Wei, Stephen R. Brooks, John J. O'Shea, Maria I. Morasso, Rasiah Loganantharaj, Hong-Wei Sun PLoS One, DOI: 10.1371/journal.pone.0127285 (2015)
Deep Sequencing Analysis of the Ixodes ricinus Haemocytome Kotsyfakis M, Kopáček P, Franta Z, Pedra JH, Ribeiro JM PLoS Negl Trop Dis, DOI://10.1371/journal.pntd.0003754 (2015)
Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus Tinoush Moulaei, Kabamba B Alexandre, Shilpa R Shenoy, Joel R Meyerson, Lauren RH Krumpe, Brian Constantine, Jennifer Wilson, Robert W Buckheit, Jr., James B McMahon, Sriram Subramaniam, Alexander Wlodawer, Barry R O'Keefe Retrovirology, doi: 10.1186/s12977-014-0127-3 (2015)
High-level expression and characterization of a thermophilic β-mannanase from Aspergillus niger in Pichia pastoris Shi Yu, Zhezhe Li, Yaping Wang, Wanping Chen, Lin Fu, Wei Tang, Chen Chen, Yunyun Liu, Xue Zhang, Lixin Ma Biotechnology Letters, doi://10.1007/s10529-015-1848-7 (2015)
Vasopressin-regulated miRNAs and AQP2-targeting miRNAs in kidney collecting duct cells Jae-Eun Kim, Hyun Jun Jung, Yu-Jung Lee, Tae-Hwan Kwon Am. J. Physiol. - Renal Physiol., DOI: 10.1152/ajprenal.00334.2014 (2015)
Cooperativity and evolution of Tetrahymena two-domain arginine kinase Noriko Okazaki, Shou Motomura, Nanaka Okazoe, Daichi Yano, Tomohiko Suzuki Int. J. Biological Macromolecules, doi:10.1016/j.ijbiomac.2015.05.034 (2015)
New findings support the association of DISC1 genetic variants with susceptibility to schizophrenia in the Han Chinese population Luo X, Jin C, Zhou Z, Shugart YY, Liu X, Zhang F, Zhang F, Zhu J, Wang Y, Cheng Z Psychiatry Res., doi: 10.1016/j.psychres.2015.05.115 (2015)
Combined influence of linker DNA and histone tails on nucleosome dynamics as revealed by microsecond molecular dynamics simulations Alexey K. Shaytana, Grigoriy A. Armeev, Alexander Goncearenco, Victor B. Zhurkin, David Landsman & Anna R. Panchenkoa J Biomol Struct Dyn., doi: 10.1080/07391102.2015.1032630. (2015)
Transcriptional activation by the thyroid hormone receptor through ligand-dependent receptor recruitment and chromatin remodelling Lars Grøntved, Joshua J. Waterfall, Dong Wook Kim, Songjoon Baek, Myong-Hee Sung, Li Zhao, Jeong Won Park, Ronni Nielsen, Robert L. Walker, Yuelin J. Zhu, Paul S. Meltzer, Gordon L. Hager & Sheue-yann Cheng Nature Communications, doi:10.1038/ncomms8048 (2015)

Elucidation of RNA binding regions of gonadotropin-regulated testicular RNA helicase (GRTH/DDX25) to transcripts of a chromatin remodeling protein essential for spermatogenesis Ruifeng Yang, Chon-Hwa Tsai-Morris, Jung Hoon Kang, Maria L. Dufau Hormone Molecular Biology and Clinical Investigation, DOI: 10.1515/hmbci-2015-0004 (2015)
A combined coarse-grained and all-atom simulation of TRPV1 channel gating and heat activation Wenjun Zheng and Feng Qin J. Gen. Physiol. , doi: 10.1085/jgp.201411335 (2015)
Mixed model and estimating equation approaches for zero inflation in clustered binary response data with application to a dating violence study Kara A. Fulton, Danping Liu, Denise L. Haynie, and Paul S. Albert The Annals of Applied Statistics, doi:10.1214/14-AOAS791 (2015)
Cortisol Stress Response in Men and Women Modulated Differentially by the Mu-Opioid Receptor Gene Polymorphism OPRM1 A118G Lovallo WR, Enoch MA, Acheson A, Cohoon AJ, Sorocco KH, Hodgkinson CA, Vincent AS, Glahn DC, Goldman D Neuropsychopharmacology., doi: 10.1038/npp.2015.101 (2015)
The DNA repair endonuclease Mus81 facilitates fast DNA replication in the absence of exogenous damage Fu H, Martin MM, Regairaz M, Huang L, You Y, Lin CM, Ryan M, Kim R, Shimura T, Pommier Y, Aladjem M Nature Communications, doi: 10.1038/ncomms7746. (2015)
miR-26a and miR-384-5p are required for LTP maintenance and spine enlargement Gu QH, Yu D, Hu Z, Liu X, Yang Y, Luo Y, Zhu J, Li Z Nature Communications, doi: 10.1038/ncomms7789 (2015)

High incidence of unrecognized visceral/neurological late-onset Niemann-Pick disease, type C1, predicted by analysis of massively parallel sequencing data sets Wassif CA, Cross JL, Iben J, Sanchez-Pulido L, Cougnoux A, Platt FM, Ory DS, Ponting CP, Bailey-Wilson JE, Biesecker LG, Porter FD Genet Med. , doi: 10.1038/gim.2015.25. (2015)
Molecular profiling and targeted therapy for advanced thoracic malignancies: a biomarker-derived, multiarm, multihistology