Biowulf High Performance Computing at the NIH
Scientific Databases

VCF

Variant Call Format for genomic data
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Database Location on HPC systemsLast Updated
1000 Genomes
20100804 release containing analysis results sets (vcfs) and README files.
/fdb/1000genomes/ 16 Nov 2017
(Updated occasionally)
Source: ftp.ncbi.nlm.nih.gov
COSMIC
Catalogue Of Somatic Mutations In Cancer, is the world's largest and most comprehensive resource for exploring the impact of somatic mutations in human cancer.
/fdb/COSMIC 07 Nov 2017
(Updated occasionally)
Source: cancer.sanger.ac.uk
dbSNP
dbSNP data from NCBI: human_9606_b144_GRCh37p13
/fdb/dbSNP/organisms/human_9606_b144_GRCh37p13/VCF 12 Aug 2015
(Updated one-time)
Source: ftp.ncbi.nlm.nih.gov
Exac release 03
Exac pulls together variant data from a variety of large-scale sequencing projects. More info at http://exac.broadinstitute.org/about
/fdb/exac/ 07 Apr 2015
(Updated after new release)
Source: ftp.broadinstitute.org
gnomAD
The genome Aggregation Database (gnomAD)
/fdb/gnomad =
(Updated one-time)
Source: gnomad.broadinstitute.org
Simons Genome Diversity Project (SGDP)
Deep genome sequencing for diverse human populations from around the world
/fdb/SGDP 17 May 2018
(Updated as needed)
Source: reichdata.hms.harvard.edu

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