Coronavirus-related work being performed on Biowulf by NIH intramural researchers includes:

• Metagenomics of Covid-19 family [Xiaofang Jiang group, NLM]
• Modeling, global surveillance, real-time genomic sequencing and phylodynamics of SARS-CoV-2 [Cecile Viboud group, FIC]
• SARS-CoV-2 RNA structural analyses [Markus Hafner group, NIAMS]
• Genome-wide association study of COVID-19 genetic variants vs. phenotypes in the UK BioBank [Andrew Johnson group, NHLBI]
• Genetic Determinants of Susceptibility to Severe COVID-19 Infection [NIAID Consortium. Director: Helen Su group, NIAID]
• Structure of complexes of the SARS-CoV-2 ectodomain with a variety of ligands [Mario Borgnia & William Copeland group, NIEHS]
• In silico screening of drug candidates [Nadya Tarasova & Giorgio Trinchieri group, NCI]
• Image processing and text mining of clinical data for the NIAID COVID Data Management Working Group [Robert Hohman group, NIAID]
• Atomic-level structure of the SARS-CoV-2 spike using cryo-electron microscopy [Peter Kwong group, NIAID_VRC]
• Covid-19 transmission modeling [Dean Follman group, NIAID]
• Text mining of COVID-related scientific literature in LitCovid and CORD-19 [Zhiyong Lu group, NLM/NCBI]
• Simulations of infection spread in populations [Vipul Periwal group, NIDDK]
• Identification of drugs that can be repurposed for COVID-19 [Eytan Ruppin group, NCI]
• Investigation of pathogenic characteristics of COVID-19 by analysis of RNA-seq data from human patients [Lothar Hennighausen group, NIDDK]
• Transcriptomics and network analysis of SARS-CoV-2 infection [Mehdi Pirooznia group, NHLBI]
• Cryo-electron microscopy of virus proteins and complexes [Natalia de Val & Eric Freed group, NCI_CCR]
• MD simulation of SARS-CoV-2 spike protein [Peter Kwong group, NIAID_VRC]

Preprints are complete and public drafts of scientific documents, not yet peer reviewed. (More about preprints)

Statistical Physics of Epidemic on Network Predictions for SARS-CoV-2 Parameters
Han, J; Cresswell-Clay, EC; Periwal, V
ArXiv (2020)

Critical Sequence Hot-spots for Binding of nCOV-2019 to ACE2 as Evaluated by Molecular Simulations
Ghorbani, M; Brooks, BR; Klauda JB
bioRxiv (2020)

Systematic Cell Line-Based Identification of Drugs Modifying ACE2 Expression
Sinha, S; Cheng, K; Aldape, K; Schiff, E; Ruppin, E
preprints.org (2020)

COVID-19-CT-CXR: a freely accessible and weakly labeled chest X-ray and CT image collection on COVID-19 from biomedical literature
Peng, Y; Tang, YX; Lee, S; Zhu, Y; Summers, RM; Lu, Z;
ArXiv (2020)

Global prediction of unreported SARS-CoV2 infection from observed COVID-19 cases
Chow, CC; Chang, JC; Gerkin, RC; Vattikuti, S;
medRxiv (2020)

Activation of the SARS-CoV-2 receptor Ace2 by cytokines through pan JAK-STAT enhancers
Hennighausen, L; Lee, HK;
bioRxiv (2020)

Network Analysis and Transcriptome Profiling Identify Autophagic and Mitochondrial Dysfunctions in SARS-CoV-2 Infection
Singh, K; Chen, YC; Judy, JT; Seifuddin, F; Tunc, I; Pirooznia, M;
bioRxiv (2020)