High-Performance Computing at the NIH
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The NIH HPC group plans, manages and supports high-performance computing systems specifically for the intramural NIH community. These systems include Biowulf, a 25,000+ processor Linux cluster; Helix, an interactive system for short jobs, Sciware, a set of applications for desktops, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.

Recent Papers that used Biowulf & HPC Resources

thumbnail image from paper Deriving frequency-dependent spatial patterns in MEG-derived resting state sensorimotor network: A novel multiband ICA technique
Nugent, A. C., Luber, B., Carver, F. W., Robinson, S. E., Coppola, R. and Zarate, C. A.
Hum. Brain Mapp. , doi:10.1002/hbm.23417 (2016)

thumbnail image from paper Additional Rare Variant Analysis in Parkinson's Disease Cases with and Without Known Pathogenic Mutations: Evidence for Oligogenic Inheritance
Steven J. Lubbe, Valentina Escott-Price et al.
Human Molecular Genetics , doi://10.1093/hmg/ddw348 (2016)

thumbnail image from paper Longitudinal imaging in C9orf72 mutation carriers: Relationship to phenotype
Mary Kay Floeter, Devin Bageac, Laura E. Danielian, Laura E. Braun, Bryan J. Traynor, , Justin Kwan
NeuroImage: Clinical , doi://10.1016/j.nicl.2016.10.014 (2016)

thumbnail image from paper Structural Characterization of Arginine Fingers: Identification of an Arginine Finger for the Pyrophosphatase dUTPases
Gergely N Nagy, Reynier Suardiaz, Anna Lopata, Oliver Ozohanics, Karoly Vekey, Bernard R. Brooks, Ibolya Leveles, Judit Toth, Beata G Vertessy, and Edina Rost
JACS , doi://10.1021/jacs.6b09012 (2016)

thumbnail image from paper Molecular lock regulates binding of glycine to a primitive NMDA receptor
Alvin Yu, Robert Alberstein, Alecia Thomas, Austin Zimmet, Richard Grey, Mark L. Mayer, and Albert Y. Lau
PNAS , doi: 10.1073/pnas.1607010113 (2016)

thumbnail image from paper Sources and implications of whole-brain fMRI signals in humans
Jonathan D Power, Mark Plitt, Timothy O Laumann, Alex Martin
Neuroimage , doi://10.1016/j.neuroimage.2016.09.038 (2016)

thumbnail image from paper Diagnosis of Parkinson's disease on the basis of clinical-genetic classification: a population-based modelling study
Mike A. Nalls, Cory Y. McLean et al.
Lancet Neurol. , doi: 10.1016/S1474-4422(15)00178-7 (2016)