High-Performance Computing at the NIH
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The NIH HPC group plans, manages and supports high-performance computing systems specifically for the intramural NIH community. These systems include Biowulf, a 60,000+ processor Linux cluster; Helix, an interactive system for short jobs, Sciware, a set of applications for desktops, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.

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Cluster Utilization
Sunday, April 30th, 2017
utilization graph
Last 24 hrs
44,718 jobs submitted
31,318 jobs completed
1,411,704 CPU hrs used
20 NIH Institutes
86 Principal Investigators
130 users

Recent Papers that used Biowulf & HPC Resources

thumbnail image from paper Intrinsic Functional Connectivity of the Central Nucleus of the Amygdala and Bed Nucleus of the Stria Terminalis
Gorka, AX; Torrisi, S; Shackman, AJ; Grillon, C; Ernst, M;
Neuroimage , DOI://10.1016/j.neuroimage.2017.03.007 (2017)

thumbnail image from paper Hydrophobic-Hydrophilic Forces in Protein Folding
Durell, SR; Ben-Naim, A;
Biopolymers , DOI://10.1002/bip.23020 (2017)

A big data approach to the development of mixed-effects models for seizure count data
Tharayil, JJ; Chiang, S; Moss, R; Stern, JM; Theodore, WH; Goldenholz, DM;
Epilepsia , DOI://10.1111/epi.13727 (2017)

thumbnail image from paper Gramicidin A Channel Formation Induces Local Lipid Redistribution II: A 3D Continuum Elastic Model
Sodt, AJ; Beaven, AH; Andersen, OS; Im, W; Pastor, RW;
Biophys. J. , DOI://10.1016/j.bpj.2017.01.035 (2017)

Automatic MR prostate segmentation by deep learning with holistically-nested networks
Ruida Cheng ; Holger R. Roth ; Nathan Lay ; Le Lu ; Baris Turkbey ; William Gandler ; Evan S. McCreedy ; Peter Choyke ; Ronald M. Summers ; Matthew J. McAuliffe
Proc. SPIE 10133, Medical Imaging 2017 , doi:10.1117/12.2254558 (2017)

thumbnail image from paper The Role of TM5 in Na2 Release and the Conformational Transition of Neurotransmitter:Sodium Symporters toward the Inward-Open State
Stolzenberg, S; Li, Z; Quick, M et al.
J. Biol. Chem. , DOI://10.1074/jbc.M116.757153 (2017)

Predicting drug-drug interactions through drug structural similarities and interaction networks incorporating pharmacokinetics and pharmacodynamics knowledge
Takeda, T; Hao, M; Cheng, T; Bryant, SH; Wang, Y;
J Cheminform , DOI://10.1186/s13321-017-0200-8 (2017)

thumbnail image from paper Modulation of opioid receptor affinity and efficacy via N-substitution of 9╬▓-hydroxy-5-(3-hydroxyphenyl)morphan: Synthesis and computer simulation study
Truong, PM; Hassan, SA; Lee, YS et al.
Bioorg. Med. Chem. , DOI://10.1016/j.bmc.2017.02.064 (2017)