COVID-19 Research Support
77.2+ Million CPU hours used
1.7+ Million jobs run
Sample projects (All projects):
- (1) Identification of drugs that can be repurposed for COVID-19
(2) Using genetic interactions like synthetic lethality and genome scale metabolic modeling to identify new drug targets and combination therapy for COVID-19 [NCI]
- Covid-19 transmission modeling and crossover trials. Developing models for flow cytometry data that will be used to gain insights into cellular immune responses to COVID-19
[NIAID]
- Metagenomics of Covid-19 family [NLM]
- Assessing newly generated and previously known compounds for activity against SARS-Cov-2 [NCI]
- Simulations of infection spread in populations [NIDDK]
- Modeling unreported SARS-Cov2 infection from observed cases, computational modeling of Covid-19 biological systems. [NIDDK]
- Genome-wide association study of COVID-19 genetic variants vs. phenotypes in the UK BioBank [NHLBI]
Biowulf users with COVID-related projects should contact the HPC staff to get increased priority for their jobs.
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Biowulf Utilization
Friday, September 17th, 2021
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Last 24 hrs
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112,894 jobs submitted
82,757 jobs completed
3,912,569 CPU hrs used
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24 NIH Institutes
241 Principal Investigators
483 users
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Announcements
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Recent Papers that used Biowulf & HPC Resources
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Immune cell deconvolution of bulk DNA methylation data reveals an association with methylation class, key somatic alterations, and cell state in glial/glioneuronal tumors
Singh, O; Pratt, D; Aldape, K; ,
Acta Neuropathol Commun
, DOI://10.1186/s40478-021-01249-9 (2021)
Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing
Xiao, W; Ren, L; Chen, Z et al.
Nat Biotechnol
, DOI://10.1038/s41587-021-00994-5 (2021)
Skin Metagenomic Sequence Analysis of Early Candida auris Outbreaks in U.S. Nursing Homes
Huang, X; Welsh, RM; Deming, C et al.
mSphere
, DOI://10.1128/mSphere.00287-21 (2021)
Toward Reducing hERG Affinities for DAT Inhibitors with a Combined Machine Learning and Molecular Modeling Approach
Lee, KH; Fant, AD; Guo, J et al.
J Chem Inf Model
, DOI://10.1021/acs.jcim.1c00856 (2021)
Identification of human long noncoding RNAs associated with nonalcoholic fatty liver disease and metabolic homeostasis
Ruan, X; Li, P; Ma, Y et al.
J Clin Invest
, DOI://10.1172/JCI136336 (2021)
Magnetization transfer weighted EPI facilitates cortical depth determination in native fMRI space
Chai, Y; Li, L; Wang, Y et al.
Neuroimage
, DOI://10.1016/j.neuroimage.2021.118455 (2021)
A Novel ARL3 Gene Mutation Associated With Autosomal Dominant Retinal Degeneration
Ratnapriya, R; Jacobson, SG; Cideciyan, AV et al.
Front Cell Dev Biol
, DOI://10.3389/fcell.2021.720782 (2021)
Determinants of conductance of a bacterial voltage-gated sodium channel
Chen, AY; Brooks, BR; Damjanovic, A; ,
Biophys J
, DOI://10.1016/j.bpj.2021.06.013 (2021)
Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations
Chen, MH; Raffield, LM; Mousas, A et al.
Cell
, DOI://10.1016/j.cell.2020.06.045 (2020)
Genetic risk scores for cardiometabolic traits in sub-Saharan African populations
Ekoru, K; Adeyemo, AA; Chen, G et al.
Int J Epidemiol
, DOI://10.1093/ije/dyab046 (2021)
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