The NIH HPC group plans, manages and supports
high-performance computing systems specifically for the
intramural NIH community. These systems include
Biowulf,
a 90,000+ processor
Linux cluster;
Helix, an interactive system for
file transfer and management,
Sciware, a set of applications
for desktops, and
Helixweb, which provides a number of web-based
scientific tools. We provide access to a wide range of computational
applications for genomics, molecular and structural biology, mathematical and
graphical analysis, image analysis, and other scientific fields.
Quick Links
Biowulf Utilization
Saturday, April 20th, 2019
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Last 24 hrs
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28,411 jobs submitted
17,588 jobs completed
2,654,278 CPU hrs used
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20 NIH Institutes
154 Principal Investigators
243 users
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Announcements
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Recent Papers that used Biowulf & HPC Resources
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Automated segmentation and quantification of aortic calcification at abdominal CT: application of a deep learning-based algorithm to a longitudinal screening cohort
Graffy, PM; Liu, J; O'Connor, S; Summers, RM; Pickhardt, PJ;
Abdom Radiol (NY)
, DOI://10.1007/s00261-019-02014-2 (2019)
A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex
Marabelli, C; Marrocco, B; Pilotto, S et al.
Cell Rep
, DOI://10.1016/j.celrep.2019.03.061 (2019)
Halogen bond interactions of novel HIV-1 protease inhibitors (PI)(GRL-001-15 and GRL-003-15) with the flap of protease are critical for their potent activity against wild-type and multi-PI-resistant HIV-1 variants
Hattori, SI; Hayashi, H; Bulut, H et al.
Antimicrob. Agents Chemother.
, DOI://10.1128/AAC.02635-18 (2019)
Parkinson's disease age at onset genome-wide association study: Defining heritability, genetic loci, and α-synuclein mechanisms
Blauwendraat, C; Heilbron, K; Vallerga, CL et al.
Mov. Disord.
, DOI://10.1002/mds.27659 (2019)
Human Influenza A Virus Hemagglutinin Glycan Evolution Follows a Temporal Pattern to a Glycan Limit
Altman, MO; Angel, M; Košík, I et al.
MBio
, DOI://10.1128/mBio.00204-19 (2019)
Shared genetic underpinnings of childhood obesity and adult cardiometabolic diseases
Tekola-Ayele, F; Lee, A; Workalemahu, T; Sánchez-Pozos, K;
Hum. Genomics
, DOI://10.1186/s40246-019-0202-x (2019)
Human-Origin Influenza A(H3N2) Reassortant Viruses in Swine, Southeast Mexico
Nelson, MI; Souza, CK; Trovão, NS et al.
Emerging Infect. Dis.
, DOI://10.3201/eid2504.180779 (2019)
Single-cell chromatin immunocleavage sequencing (scChIC-seq) to profile histone modification
Ku, WL; Nakamura, K; Gao, W et al.
Nat. Methods
, DOI://10.1038/s41592-019-0361-7 (2019)
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