The NIH HPC group plans, manages and supports high-performance computing systems specifically for use by the intramural NIH community. These systems include Biowulf, a 105,000+ processor Linux cluster; Helix, an interactive system for file transfer and management, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.

Current Status     Batch system - Scheduled maintenance
Biowulf cluster - Scheduled maintenance
Biowulf login node - Scheduled maintenance
Filesystems - Scheduled maintenance
Globus - Scheduled maintenance
HPCDrive - Scheduled maintenance
Helix - Scheduled maintenance
Mascot - Scheduled maintenance
NX/NoMachine - Scheduled maintenance
Object Store - Scheduled maintenance
Partek Flow - Scheduled maintenance
User Dashboard - Scheduled maintenance

Quick Links

Biowulf Utilization
Wednesday, September 18th, 2024
utilization graph
Last 24 hrs
61,731 jobs submitted
35,818 jobs completed
1,682,074 CPU hrs used
24 NIH Institutes
296 Principal Investigators
657 users

Announcements
Recent Papers that used Biowulf & HPC Resources

Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization
Willems, SM; Ng, NHJ; Fernandez, J et al.
Wellcome Open Res , DOI://10.12688/wellcomeopenres.18754.1 (2023)


thumbnail image from paper Sexually dimorphic renal expression of mouse Klotho is directed by a kidney-specific distal enhancer responsive to HNF1b
Jankowski, J; Lee, HK; Liu, C et al.
Commun Biol , DOI://10.1038/s42003-024-06855-6 (2024)


thumbnail image from paper A sex-stratified analysis of the genetic architecture of human brain anatomy
Shafee, R; Moraczewski, D; Liu, S et al.
Nat Commun , DOI://10.1038/s41467-024-52244-2 (2024)


thumbnail image from paper AlphaFold predictions of fold-switched conformations are driven by structure memorization
Chakravarty, D; Schafer, JW; Chen, EA et al.
Nat Commun , DOI://10.1038/s41467-024-51801-z (2024)


Retracing the evolution of Pneumocystis species, with a focus on the human pathogen Pneumocystis jirovecii
Cissé, OH; Ma, L; Kovacs, JA; ,
Microbiol Mol Biol Rev , DOI://10.1128/mmbr.00202-22 (2024)


thumbnail image from paper The recovery of parabolic avalanches in spatially subsampled neuronal networks at criticality
Srinivasan, K; Ribeiro, TL; Kells, P; Plenz, D; ,
Sci Rep , DOI://10.1038/s41598-024-70014-4 (2024)


Maternal age is related to offspring DNA methylation: A meta-analysis of results from the PACE consortium
Yeung, E; Biedrzycki, RJ; Gómez Herrera, LC et al.
Aging Cell , DOI://10.1111/acel.14194 (2024)


thumbnail image from paper ModDotPlot-rapid and interactive visualization of tandem repeats
Sweeten, AP; Schatz, MC; Phillippy, AM; ,
Bioinformatics , DOI://10.1093/bioinformatics/btae493 (2024)