Biowulf High Performance Computing at the NIH

The NIH HPC group plans, manages and supports high-performance computing systems specifically for the intramural NIH community. These systems include Biowulf, a 90,000+ processor Linux cluster; Helix, an interactive system for file transfer and management, Sciware, a set of applications for desktops, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.

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Biowulf Utilization
Thursday, February 21st, 2019
utilization graph
Last 24 hrs
82,414 jobs submitted
51,432 jobs completed
3,106,477 CPU hrs used
23 NIH Institutes
200 Principal Investigators
388 users

Recent Papers that used Biowulf & HPC Resources

thumbnail image from paper Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses
Kanekiyo, M; Joyce, MG; Gillespie, RA et al.
Nat. Immunol. , DOI://10.1038/s41590-018-0305-x (2019)

thumbnail image from paper Spatial Attention Deficits Are Causally Linked to an Area in Macaque Temporal Cortex
Bogadhi, AR; Bollimunta, A; Leopold, DA; Krauzlis, RJ;
Curr. Biol. , DOI://10.1016/j.cub.2019.01.028 (2019)

thumbnail image from paper Simultaneous targeting of linked loci in mouse embryos using base editing
Lee, HK; Willi, M; Smith, HE et al.
Sci Rep , DOI://10.1038/s41598-018-33533-5 (2019)

thumbnail image from paper Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration
Ratnapriya, R; Sosina, OA; Starostik, MR et al.
Nat. Genet. , DOI://10.1038/s41588-019-0351-9 (2019)

thumbnail image from paper Exome genotyping and linkage analysis identifies two novel linked regions and replicates two others for myopia in Ashkenazi Jewish families
Simpson, CL; Musolf, AM; Li, Q et al.
BMC Med. Genet. , DOI://10.1186/s12881-019-0752-8 (2019)

thumbnail image from paper Interpretation of spectroscopic data using molecular simulations for the secondary active transporter BetP
Leone, V; Waclawska, I; Kossmann, K et al.
J. Gen. Physiol. , DOI://10.1085/jgp.201812111 (2019)

thumbnail image from paper Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis
Bandres-Ciga, S; Noyce, AJ; Hemani, G et al.
Ann. Neurol. , DOI://10.1002/ana.25431 (2019)

The prevalence of germline DICER1 pathogenic variation in cancer populations
Kim, J; Schultz, KAP; Hill, DA; Stewart, DR;
Mol Genet Genomic Med , DOI://10.1002/mgg3.555 (2019)