Biowulf High Performance Computing at the NIH

The NIH HPC group plans, manages and supports high-performance computing systems specifically for the intramural NIH community. These systems include Biowulf, a 90,000+ processor Linux cluster; Helix, an interactive system for file transfer and management, Sciware, a set of applications for desktops, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.

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Biowulf Utilization
Monday, November 19th, 2018
utilization graph
Last 24 hrs
50,305 jobs submitted
30,312 jobs completed
2,538,346 CPU hrs used
20 NIH Institutes
125 Principal Investigators
188 users

Recent Papers that used Biowulf & HPC Resources

thumbnail image from paper Mechanism of FACT removal from transcribed genes by anticancer drugs curaxins
Chang, HW; Valieva, ME; Safina, A et al.
Sci Adv , DOI://10.1126/sciadv.aav2131 (2018)

thumbnail image from paper Practical issues in using generalized estimating equations for inference on transitions in longitudinal data: What is being estimated
Bible, J; Albert, PS; Simons-Morton, BG; Liu, D;
Stat Med , DOI://10.1002/sim.8014 (2018)

thumbnail image from paper Whole-exome sequencing of nevoid basal cell carcinoma syndrome families and review of Human Gene Mutation Database PTCH1 mutation data
Gianferante, DM; Rotunno, M; Dean, M et al.
Mol Genet Genomic Med , DOI://10.1002/mgg3.498 (2018)

thumbnail image from paper A fast adaptive algorithm for computing whole-genome homology maps
Chirag Jain, Sergey Koren, Alexander Dilthey, Adam M Phillippy, and Srinivas Aluru
Bioinformatics , doi://10.1093/bioinformatics/bty597 (2018)

thumbnail image from paper Integrated Epigenetic Mapping of Human and Mouse Salivary Gene Regulation
Michael, DG; Pranzatelli, TJF; Warner, BM; Yin, H; Chiorini, JA;
J. Dent. Res. , DOI://10.1177/0022034518806518 (2018)

thumbnail image from paper Clonal expansion and compartmentalized maintenance of rhesus macaque NK cell subsets
Wu, C; Espinoza, DA; Koelle, SJ et al.
Sci Immunol , DOI://10.1126/sciimmunol.aat9781 (2018)

thumbnail image from paper RefSeq database growth influences the accuracy of k-mer-based lowest common ancestor species identification
Nasko, DJ; Koren, S; Phillippy, AM; Treangen, TJ;
Genome Biol. , DOI://10.1186/s13059-018-1554-6 (2018)

thumbnail image from paper Non-canonical Drosophila X chromosome dosage compensation and repressive topologically associated domains
Lee, H; Oliver, B;
Epigenetics Chromatin , DOI://10.1186/s13072-018-0232-y (2018)