High-Performance Computing at the NIH
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The NIH HPC group plans, manages and supports high-performance computing systems specifically for the intramural NIH community. These systems include Biowulf, a 90,000+ processor Linux cluster; Helix, an interactive system for short jobs, Sciware, a set of applications for desktops, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.



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Cluster Utilization
Tuesday, August 22nd, 2017
utilization graph
Last 24 hrs
38,541 jobs submitted
21,346 jobs completed
2,519,917 CPU hrs used
21 NIH Institutes
128 Principal Investigators
222 users

Announcements
Recent Papers that used Biowulf & HPC Resources

thumbnail image from paper MLL4 prepares the enhancer landscape for Foxp3 induction via chromatin looping
Placek, K; Hu, G; Cui, K et al.
Nat. Immunol. , DOI://10.1038/ni.3812 (2017)

Therapeutic Antibodies to Ganglioside GD2 Evolved from Highly Selective Germline Antibodies
Sterner, E; Peach, ML; Nicklaus, MC; Gildersleeve, JC;
Cell Rep , DOI://10.1016/j.celrep.2017.07.050 (2017)

thumbnail image from paper Hydroxyl-radical footprinting combined with molecular modeling identifies unique features of DNA conformation and nucleosome positioning
Alexey K. Shaytan, Hua Xiao, Grigoriy A. Armeev, Carl Wu, David Landsman, Anna R. Panchenko
Nucleic Acids Res. , doi://10.1093/nar/gkx616 (2017)

thumbnail image from paper Functional Subpopulations of Neurons in a Macaque Face Patch Revealed by Single-Unit fMRI Mapping
Soo Hyun Park, Brian E. Russ, David B.T. McMahon, Kenji W. Koyano, Rebecca A. Berman, David A. Leopold
Neuron , doi://10.1016/j.neuron.2017.07.014 (2017)

Palmitoylation contributes to membrane curvature in Influenza A virus assembly and hemagglutinin-mediated membrane fusion
Chlanda, P; Mekhedov, E; Waters, H et al.
J. Virol. , DOI://10.1128/JVI.00947-17 (2017)

thumbnail image from paper Survival in adults and children with systemic lupus erythematosus: a systematic review and Bayesian meta-analysis of studies from 1950 to 2016
Tektonidou, MG; Lewandowski, LB; Hu, J; Dasgupta, A; Ward, MM;
Ann. Rheum. Dis. , DOI://10.1136/annrheumdis-2017-211663 (2017)

thumbnail image from paper A Novel Method To Estimate Lymphocyte Dose And Application To Pediatric And Young Adult Ct Patients In The United Kingdom
Choonsik Lee, Lindsay M. Morton, Amy Berrington de Gonzalez
Radiation Dosimetry , doi://10.1093/rpd/ncx084 (2017)

thumbnail image from paper Does accounting for seizure frequency variability increase clinical trial power
Goldenholz, DM; Goldenholz, SR; Moss, R et al.
Epilepsy Res. , DOI://10.1016/j.eplepsyres.2017.07.013 (2017)