Biowulf High Performance Computing at the NIH

The NIH HPC group plans, manages and supports high-performance computing systems specifically for the intramural NIH community. These systems include Biowulf, a 90,000+ processor Linux cluster; Helix, an interactive system for file transfer and management, Sciware, a set of applications for desktops, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.

Current Status    All Services Operational

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Biowulf Utilization
Wednesday, April 1st, 2020
utilization graph
Last 24 hrs
141,684 jobs submitted
109,364 jobs completed
2,876,043 CPU hrs used
26 NIH Institutes
213 Principal Investigators
408 users

Recent Papers that used Biowulf & HPC Resources

thumbnail image from paper YAP1/TAZ-TEAD transcriptional networks maintain skin homeostasis by regulating cell proliferation and limiting KLF4 activity
Yuan, Y; Park, J; Feng, A et al.
Nat Commun , DOI://10.1038/s41467-020-15301-0 (2020)

thumbnail image from paper De novo assembly of the cattle reference genome with single-molecule sequencing
Rosen, BD; Bickhart, DM; Schnabel, RD et al.
Gigascience , DOI://10.1093/gigascience/giaa021 (2020)

thumbnail image from paper Prediction of stress and drug craving ninety minutes in the future with passively collected GPS data
Epstein, DH; Tyburski, M; Kowalczyk, WJ et al.
NPJ Digit Med , DOI://10.1038/s41746-020-0234-6 (2020)

thumbnail image from paper Interplay between DNA damage repair and apoptosis shapes cancer evolution through aneuploidy and microsatellite instability
Auslander, N; Wolf, YI; Koonin, EV;
Nat Commun , DOI://10.1038/s41467-020-15094-2 (2020)

thumbnail image from paper Multiple lipid binding sites determine the affinity of PH domains for phosphoinositide-containing membranes
Yamamoto, E; Domanski, J; Naughton, FB et al.
Sci Adv , DOI://10.1126/sciadv.aay5736 (2020)

thumbnail image from paper Tick-Borne Encephalitis Virus Infection Alters the Sialome of Ixodes ricinus Ticks During the Earliest Stages of Feeding
Hart, CE; Ribeiro, JM; Kazimirova, M; Thangamani, S;
Front Cell Infect Microbiol , DOI://10.3389/fcimb.2020.00041 (2020)

thumbnail image from paper Low-frequency parietal repetitive transcranial magnetic stimulation reduces fear and anxiety
Balderston, NL; Beydler, EM; Goodwin, M et al.
Transl Psychiatry , DOI://10.1038/s41398-020-0751-8 (2020)

thumbnail image from paper Molecular and cellular determinants of motor asymmetry in zebrafish
Horstick, EJ; Bayleyen, Y; Burgess, HA;
Nat Commun , DOI://10.1038/s41467-020-14965-y (2020)