The NIH HPC group plans, manages and supports high-performance computing systems specifically for use by the intramural NIH community. These systems include Biowulf, a 105,000+ processor Linux cluster; Helix, an interactive system for file transfer and management, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.

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Biowulf Utilization
Saturday, July 27th, 2024
utilization graph
Last 24 hrs
100,992 jobs submitted
78,741 jobs completed
2,940,295 CPU hrs used
23 NIH Institutes
282 Principal Investigators
627 users

Announcements
Recent Papers that used Biowulf & HPC Resources

thumbnail image from paper Genetic distance and ancestry proportion modify the association between maternal genetic risk score of type 2 diabetes and fetal growth
Habtewold, TD; Wijesiriwardhana, P; Biedrzycki, RJ; Tekola-Ayele, F; ,
Hum Genomics , DOI://10.1186/s40246-024-00645-1 (2024)


thumbnail image from paper Weakly-Supervised Detection of Bone Lesions in CT
Sheng, T; Mathai, TS; Shieh, A; Summers, RM; ,
Proc SPIE Int Soc Opt Eng , DOI://10.1117/12.3008823 (2024)


thumbnail image from paper The landscape of rare genetic variants in familial Waldenström macroglobulinemia
Pemov, A; Kim, J; Luo, W et al.
Blood Neoplasia , DOI://10.1016/j.bneo.2024.100013 (2024)


Whole-genome sequence of Mucor velutinosus NIH1002, a strain associated with disseminated disease
Conlan, S; Subramanian, P; Plata Barril, B et al.
Microbiol Resour Announc , DOI://10.1128/mra.00062-24 (2024)


thumbnail image from paper Mriyaviruses: small relatives of giant viruses
Yutin, N; Mutz, P; Krupovic, M; Koonin, EV; ,
mBio , DOI://10.1128/mbio.01035-24 (2024)


thumbnail image from paper Papillary tumor of the pineal region: analysis of DNA methylation profiles and clinical outcomes in 76 cases
Wu, Z; Dazelle, K; Abdullaev, Z et al.
Acta Neuropathol Commun , DOI://10.1186/s40478-024-01781-4 (2024)


thumbnail image from paper K128 ubiquitination constrains RAS activity by expanding its binding interface with GAP proteins
Magits, W; Steklov, M; Jang, H et al.
EMBO J , DOI://10.1038/s44318-024-00146-w (2024)


thumbnail image from paper Evaluation of the Therapeutic Potential of Sulfonyl Urea Derivatives as Soluble Epoxide Hydrolase (sEH) Inhibitors
Kundu, B; Dvorácskó, S; Basu, A et al.
Molecules , DOI://10.3390/molecules29133036 (2024)