Biowulf High Performance Computing at the NIH

The NIH HPC group plans, manages and supports high-performance computing systems specifically for the intramural NIH community. These systems include Biowulf, a 90,000+ processor Linux cluster; Helix, an interactive system for file transfer and management, Sciware, a set of applications for desktops, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.

Current Status    All Services Operational

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Biowulf Utilization
Friday, December 6th, 2019
utilization graph
Last 24 hrs
125,673 jobs submitted
92,875 jobs completed
3,086,442 CPU hrs used
25 NIH Institutes
215 Principal Investigators
430 users

Recent Papers that used Biowulf & HPC Resources

thumbnail image from paper Katanin Grips the β-Tubulin Tail through an Electropositive Double Spiral to Sever Microtubules
Zehr, EA; Szyk, A; Szczesna, E; Roll-Mecak, A;
Dev. Cell , DOI://10.1016/j.devcel.2019.10.010 (2019)

thumbnail image from paper Data augmentation using generative adversarial networks (CycleGAN) to improve generalizability in CT segmentation tasks
Sandfort, V; Yan, K; Pickhardt, PJ; Summers, RM;
Sci Rep , DOI://10.1038/s41598-019-52737-x (2019)

thumbnail image from paper Preventing dysbiosis of the neonatal mouse intestinal microbiome protects against late-onset sepsis
Singer, JR; Blosser, EG; Zindl, CL et al.
Nat. Med. , DOI://10.1038/s41591-019-0640-y (2019)

thumbnail image from paper Splicing factor DHX15 affects tp53 and mdm2 expression via alternate splicing and promoter usage
McElderry, J; Carrington, B; Bishop, K et al.
Hum. Mol. Genet. , DOI://10.1093/hmg/ddz261 (2019)

thumbnail image from paper Tango1 coordinates the formation of ER/Golgi docking sites to mediate secretory granule formation
Reynolds, HM; Zhang, L; Tran, DT; Ten Hagen, KG;
J. Biol. Chem. , DOI://10.1074/jbc.RA119.011063 (2019)

thumbnail image from paper Reducing motion sensitivity in 3D high-resolution T2*-weighted MRI by navigator-based motion and nonlinear magnetic field correction
Liu, J; van Gelderen, P; de Zwart, JA; Duyn, JH;
Neuroimage , DOI://10.1016/j.neuroimage.2019.116332 (2019)

thumbnail image from paper Williams syndrome hemideletion and LIMK1 variation both affect dorsal stream functional connectivity
Gregory, MD; Mervis, CB; Elliott, ML et al.
Brain , DOI://10.1093/brain/awz323 (2019)

thumbnail image from paper Characteristics of respiratory measures in young adults scanned at rest, including systematic changes and "missed" deep breaths
Power, JD; Lynch, CJ; Dubin, MJ; Silver, BM; Martin, A; Jones, RM;
Neuroimage , DOI://10.1016/j.neuroimage.2019.116234 (2019)