High-Performance Computing at the NIH
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The NIH HPC group plans, manages and supports high-performance computing systems specifically for the intramural NIH community. These systems include Biowulf, a 60,000+ processor Linux cluster; Helix, an interactive system for short jobs, Sciware, a set of applications for desktops, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.



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Cluster Utilization
Tuesday, February 21st, 2017
utilization graph
Last 24 hrs
44,729 jobs submitted
24,513 jobs completed
1,448,314 CPU hrs used
19 NIH Institutes
81 Principal Investigators
135 users

Announcements
Recent Papers that used Biowulf & HPC Resources

Circulating miRNA Associated with Posttraumatic Stress Disorder in a Cohort of Military Combat Veterans
Christiana G. Martin, Hyungsuk Kim, Sijung Yun, Whitney Livingston, Joseph Fetta, Vincent Mysliwiec, Tristin Baxter, Jessica M. Gill
Psychiatry Research , doi://10.1016/j.psychres.2017.01.081 (2017)

thumbnail image from paper The dynamic mechanism of RASSF5 and MST kinase activation by Ras
Liao, TJ; Jang, H; Tsai, CJ; Fushman, D; Nussinov, R;
Phys Chem Chem Phys , DOI://10.1039/c6cp08596b (2017)

thumbnail image from paper MNase-Sensitive Complexes in Yeast: Nucleosomes and Non-histone Barriers
Chereji, RV; Ocampo, J; Clark, DJ;
Mol. Cell , DOI://10.1016/j.molcel.2016.12.009 (2017)

thumbnail image from paper Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing
Jansen, IE; Ye, H; Heetveld, S et al.
Genome Biol. , DOI://10.1186/s13059-017-1147-9 (2017)

thumbnail image from paper Differential methylation of genes in individuals exposed to maternal diabetes in utero
Chen, P; Piaggi, P; Traurig, M et al.
Diabetologia , DOI://10.1007/s00125-016-4203-1 (2017)

thumbnail image from paper Frequent inactivating germline mutations in DNA repair genes in patients with Ewing sarcoma
Brohl, AS; Patidar, R; Turner, CE et al.
Genet. Med. , DOI://10.1038/gim.2016.206 (2017)

thumbnail image from paper SDHD promoter mutations ablate GABP transcription factor binding in melanoma
Zhang, T; Xu, M; Makowski, MM et al.
Cancer Res. , DOI://10.1158/0008-5472.CAN-16-0919 (2017)

thumbnail image from paper Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach
Mendelson, MM; Marioni, RE; Joehanes, R et al.
PLoS Med. , DOI://10.1371/journal.pmed.1002215 (2017)