Biowulf High Performance Computing at the NIH

The NIH HPC group plans, manages and supports high-performance computing systems specifically for the intramural NIH community. These systems include Biowulf, a 90,000+ processor Linux cluster; Helix, an interactive system for file transfer and management, Sciware, a set of applications for desktops, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.

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Biowulf Utilization
Friday, January 18th, 2019
utilization graph
Last 24 hrs
199,153 jobs submitted
167,405 jobs completed
2,997,060 CPU hrs used
23 NIH Institutes
211 Principal Investigators
379 users

Announcements
Recent Papers that used Biowulf & HPC Resources

thumbnail image from paper The mitochondrial type IB topoisomerase drives mitochondrial translation and carcinogenesis
Baechler, SA; Factor, VM; Dalla Rosa, I et al.
Nat Commun , DOI://10.1038/s41467-018-07922-3 (2019)

thumbnail image from paper Decrypting the Heat Activation Mechanism of TRPV1 Channel by Molecular Dynamics Simulation
Wen, H; Zheng, W;
Biophys. J. , DOI://10.1016/j.bpj.2017.10.034 (2018)

thumbnail image from paper Re-annotation of eight Drosophila genomes
Yang, H; Jaime, M; Polihronakis, M et al.
Life Sci Alliance , DOI://10.26508/lsa.201800156 (2018)

thumbnail image from paper The phenotypic landscape of a Tbc1d24 mutant mouse includes convulsive seizures resembling human early infantile epileptic encephalopathy
Tona, R; Chen, W; Nakano, Y et al.
Hum. Mol. Genet. , DOI://10.1093/hmg/ddy445 (2019)

thumbnail image from paper Secondary Metabolites from the Fungus Dictyosporium sp. and Their MALT1 Inhibitory Activities
Tran, TD; Wilson, BAP; Henrich, CJ et al.
J. Nat. Prod. , DOI://10.1021/acs.jnatprod.8b00871 (2019)

thumbnail image from paper Dose coefficients of mesh-type ICRP reference computational phantoms for idealized external exposures of photons and electrons
Yeom YS; Choi C; et al
Nuclear Engineering and Technology , doi://10.1016/j.net.2018.12.006 (2018)

thumbnail image from paper The shape of the bacterial ribosome exit tunnel affects cotranslational protein folding
Kudva, R; Tian, P; Pardo-Avila, F et al.
Elife , DOI://10.7554/eLife.36326 (2018)

thumbnail image from paper Investigation of a Cluster of Sphingomonas koreensis Infections
Johnson, RC; Deming, C; Conlan, S et al.
N. Engl. J. Med. , DOI://10.1056/NEJMoa1803238 (2018)