Biowulf High Performance Computing at the NIH

The NIH HPC group plans, manages and supports high-performance computing systems specifically for the intramural NIH community. These systems include Biowulf, a 90,000+ processor Linux cluster; Helix, an interactive system for file transfer and management, Sciware, a set of applications for desktops, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.

Current Status    All Services Operational

Quick Links

Biowulf Utilization
Saturday, October 19th, 2019
utilization graph
Last 24 hrs
109,704 jobs submitted
80,446 jobs completed
3,363,605 CPU hrs used
24 NIH Institutes
199 Principal Investigators
374 users

Announcements
Recent Papers that used Biowulf & HPC Resources

Differences in Genome-wide DNA Methylation Profiles in Breast Milk by Race and Lactation Duration
Davis Lynn, BC; Bodelon, C; Pfeiffer, RM et al.
Cancer Prev Res (Phila) , DOI://10.1158/1940-6207.CAPR-19-0169 (2019)

thumbnail image from paper Cell Type- and Sex-Dependent Transcriptome Profiles of Rat Anterior Pituitary Cells
Fletcher, PA; Smiljanic, K; Maso Prévide, R et al.
Front Endocrinol (Lausanne) , DOI://10.3389/fendo.2019.00623 (2019)

thumbnail image from paper Strong dependence of the nano-bio interactions on core morphology and layer composition of ultrasmall nanostructures
Hassan, SA
J Chem Phys , DOI://10.1063/1.5115192 (2019)

thumbnail image from paper Discovery and Development of Anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication
Maeda, K; Das, D; Kobayakawa, T; Tamamura, H; Takeuchi, H;
Curr Top Med Chem , DOI://10.2174/1568026619666190712204603 (2019)

thumbnail image from paper Molecular Classification of Epithelial Ovarian Cancer Based on Methylation Profiling: Evidence for Survival Heterogeneity
Bodelon, C; Killian, JK; Sampson, JN et al.
Clin. Cancer Res. , DOI://10.1158/1078-0432.CCR-18-3720 (2019)

thumbnail image from paper Layer-dependent activity in human prefrontal cortex during working memory
Finn, ES; Huber, L; Jangraw, DC; Molfese, PJ; Bandettini, PA;
Nat. Neurosci. , DOI://10.1038/s41593-019-0487-z (2019)

thumbnail image from paper Dynamic Emergence of Mismatch Repair Deficiency Facilitates Rapid Evolution of Ceftazidime-Avibactam Resistance in Pseudomonas aeruginosa Acute Infection
Khil, PP; Dulanto Chiang, A; Ho, J et al.
MBio , DOI://10.1128/mBio.01822-19 (2019)

thumbnail image from paper Drosophila Heterochromatin Stabilization Requires the Zinc-Finger Protein Small Ovary
Benner, L; Castro, EA; Whitworth, C et al.
Genetics , DOI://10.1534/genetics.119.302590 (2019)