NIH HPC Systems

The NIH HPC group plans, manages and supports high-performance computing systems specifically for the intramural NIH community. These systems include Biowulf, a 90,000+ processor Linux cluster; Helix, an interactive system for file transfer and management, Sciware, a set of applications for desktops, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.

Current Status

All Services Operational

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Biowulf Utilization

Saturday, December 14th, 2019

Last 24 hrs
123,397 jobs submitted 94,374 jobs completed 3,421,827 CPU hrs used	26 NIH Institutes 230 Principal Investigators 453 users

Announcements

(All)

REMINDER: Walk-In Consult with HPC staff Wed 11 Dec (Dec 10th 2019)
A Python 3 module will become the default module on biowulf in April 2020 (Dec 9th 2019)
Walk-In Consult with HPC staff Wed 11 Dec (Dec 4th 2019)
Reminder: Final Biowulf 20th anniversary seminar: Dr Alexander Sodt (NICHD) on 3 Dec (Dec 2nd 2019)
Final Biowulf 20th anniversary seminar: Dr Alexander Sodt (NICHD) (Nov 25th 2019)
Upcoming NIH HPC class "Deep Learning by Example on Biowulf - Class #3" (Nov 15th 2019)
Upcoming NIH HPC classes in Dec 2019 - CORRECTED DATES (Nov 12th 2019)

Recent Papers that used Biowulf & HPC Resources

(All publications)

Katanin Grips the β-Tubulin Tail through an Electropositive Double Spiral to Sever Microtubules
Zehr, EA; Szyk, A; Szczesna, E; Roll-Mecak, A;
Dev. Cell , DOI://10.1016/j.devcel.2019.10.010 (2019)

Data augmentation using generative adversarial networks (CycleGAN) to improve generalizability in CT segmentation tasks
Sandfort, V; Yan, K; Pickhardt, PJ; Summers, RM;
Sci Rep , DOI://10.1038/s41598-019-52737-x (2019)

Preventing dysbiosis of the neonatal mouse intestinal microbiome protects against late-onset sepsis
Singer, JR; Blosser, EG; Zindl, CL et al.
Nat. Med. , DOI://10.1038/s41591-019-0640-y (2019)

Splicing factor DHX15 affects tp53 and mdm2 expression via alternate splicing and promoter usage
McElderry, J; Carrington, B; Bishop, K et al.
Hum. Mol. Genet. , DOI://10.1093/hmg/ddz261 (2019)

Tango1 coordinates the formation of ER/Golgi docking sites to mediate secretory granule formation
Reynolds, HM; Zhang, L; Tran, DT; Ten Hagen, KG;
J. Biol. Chem. , DOI://10.1074/jbc.RA119.011063 (2019)

Reducing motion sensitivity in 3D high-resolution T2*-weighted MRI by navigator-based motion and nonlinear magnetic field correction
Liu, J; van Gelderen, P; de Zwart, JA; Duyn, JH;
Neuroimage , DOI://10.1016/j.neuroimage.2019.116332 (2019)

Williams syndrome hemideletion and LIMK1 variation both affect dorsal stream functional connectivity
Gregory, MD; Mervis, CB; Elliott, ML et al.
Brain , DOI://10.1093/brain/awz323 (2019)

Characteristics of respiratory measures in young adults scanned at rest, including systematic changes and "missed" deep breaths
Power, JD; Lynch, CJ; Dubin, MJ; Silver, BM; Martin, A; Jones, RM;
Neuroimage , DOI://10.1016/j.neuroimage.2019.116234 (2019)