NIH HPC Systems

The NIH HPC group plans, manages and supports high-performance computing systems specifically for the intramural NIH community. These systems include Biowulf, a 90,000+ processor Linux cluster; Helix, an interactive system for file transfer and management, Sciware, a set of applications for desktops, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.

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Biowulf Utilization

Friday, January 18th, 2019

Last 24 hrs
199,153 jobs submitted 167,405 jobs completed 2,997,060 CPU hrs used	23 NIH Institutes 211 Principal Investigators 379 users

Announcements

(All)

New HPC classes in 2019 (Jan 15th 2019)
Walk-In Consult with HPC staff Wed 16 Jan (Jan 9th 2019)
Reminder: Potential new classes offered by the NIH HPC staff (Dec 12th 2018)
Upcoming NIH HPC classes in Jan 2019 (Dec 12th 2018)
REMINDER: Walk-In Consult with HPC staff Wed 12 Dec (Dec 11th 2018)
Potential new classes offered by the NIH HPC staff (Dec 10th 2018)
Walk-In Consult with HPC staff Wed 12 Dec (Dec 5th 2018)

Recent Papers that used Biowulf & HPC Resources

(All publications)

The mitochondrial type IB topoisomerase drives mitochondrial translation and carcinogenesis
Baechler, SA; Factor, VM; Dalla Rosa, I et al.
Nat Commun , DOI://10.1038/s41467-018-07922-3 (2019)

Decrypting the Heat Activation Mechanism of TRPV1 Channel by Molecular Dynamics Simulation
Wen, H; Zheng, W;
Biophys. J. , DOI://10.1016/j.bpj.2017.10.034 (2018)

Re-annotation of eight Drosophila genomes
Yang, H; Jaime, M; Polihronakis, M et al.
Life Sci Alliance , DOI://10.26508/lsa.201800156 (2018)

The phenotypic landscape of a Tbc1d24 mutant mouse includes convulsive seizures resembling human early infantile epileptic encephalopathy
Tona, R; Chen, W; Nakano, Y et al.
Hum. Mol. Genet. , DOI://10.1093/hmg/ddy445 (2019)

Secondary Metabolites from the Fungus Dictyosporium sp. and Their MALT1 Inhibitory Activities
Tran, TD; Wilson, BAP; Henrich, CJ et al.
J. Nat. Prod. , DOI://10.1021/acs.jnatprod.8b00871 (2019)

Dose coefficients of mesh-type ICRP reference computational phantoms for idealized external exposures of photons and electrons
Yeom YS; Choi C; et al
Nuclear Engineering and Technology , doi://10.1016/j.net.2018.12.006 (2018)

The shape of the bacterial ribosome exit tunnel affects cotranslational protein folding
Kudva, R; Tian, P; Pardo-Avila, F et al.
Elife , DOI://10.7554/eLife.36326 (2018)

Investigation of a Cluster of Sphingomonas koreensis Infections
Johnson, RC; Deming, C; Conlan, S et al.
N. Engl. J. Med. , DOI://10.1056/NEJMoa1803238 (2018)