Biowulf High Performance Computing at the NIH

The NIH HPC group plans, manages and supports high-performance computing systems specifically for the intramural NIH community. These systems include Biowulf, a 90,000+ processor Linux cluster; Helix, an interactive system for file transfer and management, Sciware, a set of applications for desktops, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.

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Biowulf Utilization
Saturday, December 15th, 2018
utilization graph
Last 24 hrs
90,773 jobs submitted
66,268 jobs completed
3,522,415 CPU hrs used
23 NIH Institutes
197 Principal Investigators
336 users

Announcements
Recent Papers that used Biowulf & HPC Resources

thumbnail image from paper Genetic analysis of neurodegenerative diseases in a pathology cohort
Blauwendraat C, Pletnikova O, Geiger, JT et al
Neurobiology of Aging , 10.1016/j.neurobiolaging.2018.11.007 (2018)

A temporal deconvolution algorithm for multiecho functional MRI
Cesar Caballero Gaudes ; Peter A. Bandettini ; Javier Gonzalez-Castillo
2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018) , 10.1109/ISBI.2018.8363649 (2018)

thumbnail image from paper Folding pathway of an Ig domain is conserved on and off the ribosome
Tian, P; Steward, A; Kudva, R et al.
Proc. Natl. Acad. Sci. U.S.A. , DOI://10.1073/pnas.1810523115 (2018)

Mosaic Y loss is moderately associated with solid tumor risk
Loftfield, E; Zhou, W; Yeager, M; Chanock, SJ; Freedman, ND; Machiela, MJ;
Cancer Res. , DOI://10.1158/0008-5472.CAN-18-2566 (2018)

thumbnail image from paper AbDesigner3D: a structure-guided tool for peptide-based antibody production
Saethang, T; Hodge, K; Kimkong, I; Payne, DM; Knepper, MA; Pisitkun, T;
Bioinformatics , DOI://10.1093/bioinformatics/bty055 (2018)

thumbnail image from paper Helios is a key transcriptional regulator of outer hair cell maturation
Chessum, L; Matern, MS; Kelly, MC et al.
Nature , DOI://10.1038/s41586-018-0728-4 (2018)

thumbnail image from paper Comparing the performance of selected variant callers using synthetic data and genome segmentation
Bian, X; Zhu, B; Wang, M et al.
BMC Bioinformatics , DOI://10.1186/s12859-018-2440-7 (2018)

thumbnail image from paper Proximity-CLIP provides a snapshot of protein-occupied RNA elements in subcellular compartments
Benhalevy, D; Anastasakis, DG; Hafner, M;
Nat. Methods , DOI://10.1038/s41592-018-0220-y (2018)