The NIH HPC group plans, manages and supports high-performance computing systems specifically for use by the intramural NIH community. These systems include Biowulf, a 105,000+ processor Linux cluster; Helix, an interactive system for file transfer and management, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.

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Biowulf Utilization
Tuesday, May 28th, 2024
utilization graph
Last 24 hrs
47,349 jobs submitted
39,206 jobs completed
2,407,549 CPU hrs used
22 NIH Institutes
178 Principal Investigators
304 users

Recent Papers that used Biowulf & HPC Resources

thumbnail image from paper Genome-wide analyses reveals an association between invasive urothelial carcinoma in the Shetland sheepdog and NIPAL1
Parker, HG; Harris, AC; Plassais, J et al.
NPJ Precis Oncol , DOI://10.1038/s41698-024-00591-0 (2024)

thumbnail image from paper Correlation of protein binding pocket properties with hits' chemistries used in generation of ultra-large virtual libraries
Song, RX; Nicklaus, MC; Tarasova, NI; ,
J Comput Aided Mol Des , DOI://10.1007/s10822-024-00562-4 (2024)

thumbnail image from paper Impacts of human mobility on the citywide transmission dynamics of 18 respiratory viruses in pre- and post-COVID-19 pandemic years
Perofsky, AC; Hansen, CL; Burstein, R et al.
Nat Commun , DOI://10.1038/s41467-024-48528-2 (2024)

thumbnail image from paper Fecal transplant from vaginally seeded infants decreases intraabdominal adiposity in mice
Namasivayam, S; Tilves, C; Ding, H et al.
Gut Microbes , DOI://10.1080/19490976.2024.2353394 (2024)

thumbnail image from paper Contrasting neurofunctional correlates of face- and visuospatial-processing in children and adolescents with Williams syndrome: convergent results from four fMRI paradigms
Garvey, MH; Nash, T; Kippenhan, JS et al.
Sci Rep , DOI://10.1038/s41598-024-60460-5 (2024)

thumbnail image from paper A Toxoplasma gondii O-glycosyltransferase that modulates bradyzoite cyst wall rigidity is distinct from host homologues
Kumar, P; Tomita, T; Gerken, TA et al.
Nat Commun , DOI://10.1038/s41467-024-48253-w (2024)

thumbnail image from paper Lessons learned from an fMRI-guided rTMS study on performance in a numerical Stroop task
Beynel, L; Gura, H; Rezaee, Z et al.
PLoS One , DOI://10.1371/journal.pone.0302660 (2024)

thumbnail image from paper Protocol for the genomic analysis of salt-fractionated chromatin from frozen murine liver
Yang, N; Sikder, S; Dalal, Y; Sen, P; ,
STAR Protoc , DOI://10.1016/j.xpro.2024.103043 (2024)