High-Performance Computing at the NIH
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The NIH HPC group plans, manages and supports high-performance computing systems specifically for the intramural NIH community. These systems include Biowulf, a 90,000+ processor Linux cluster; Helix, an interactive system for short jobs, Sciware, a set of applications for desktops, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.

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Biowulf Utilization
Saturday, March 24th, 2018
utilization graph
Last 24 hrs
94,501 jobs submitted
58,656 jobs completed
3,109,458 CPU hrs used
21 NIH Institutes
177 Principal Investigators
312 users

Recent Papers that used Biowulf & HPC Resources

thumbnail image from paper Shep regulates Drosophila neuronal remodeling by controlling transcription of its chromatin targets
Chen, D; Dale, RK; Lei, EP;
Development , DOI://10.1242/dev.154047 (2018)

thumbnail image from paper Balancing Force Field Protein-Lipid Interactions To Capture Transmembrane Helix-Helix Association
Domanski, J; Sansom, MSP; Stansfeld, PJ; Best, RB;
J Chem Theory Comput , DOI://10.1021/acs.jctc.7b00983 (2018)

thumbnail image from paper Progressive and Multi-path Holistically Nested Neural Networks for Pathological Lung Segmentation from CT Images
Harrison A.P., Xu Z., George K., Lu L., Summers R.M., Mollura D.J.
In: Descoteaux M., Maier-Hein L., Franz A., Jannin P., Colli , 10.1007/978-3-319-66179-7_71 (2017)

thumbnail image from paper LMTK3 confers chemo-resistance in breast cancer
Stebbing, J; Shah, K; Lit, LC et al.
Oncogene , DOI://10.1038/s41388-018-0197-0 (2018)

thumbnail image from paper A deep insight into the male and female sialotranscriptome of adult Culex tarsalis mosquitoes
Ribeiro, JMC; Martin-Martin, I; Moreira, FR; Bernard, KA; Calvo, E;
Insect Biochem. Mol. Biol. , DOI://10.1016/j.ibmb.2018.03.001 (2018)

thumbnail image from paper Argonaute2 and LaminB modulate gene expression by controlling chromatin topology
Nazer, E; Dale, RK; Chinen, M; Radmanesh, B; Lei, EP;
PLoS Genet. , DOI://10.1371/journal.pgen.1007276 (2018)

thumbnail image from paper Mechanism of Darunavir (DRV)'s High Genetic Barrier to HIV-1 Resistance: A Key V32I Substitution in Protease Rarely Occurs, but Once It Occurs, It Predisposes HIV-1 To Develop DRV Resistance
Aoki, M; Das, D; Hayashi, H et al.
MBio , DOI://10.1128/mBio.02425-17 (2018)

thumbnail image from paper Co-evolutionary fitness landscapes for sequence design
Tian, P; Louis, JM; Baber, JL; Aniana, A; Best, R;
Angew. Chem. Int. Ed. Engl. , DOI://10.1002/anie.201713220 (2018)