High-Performance Computing at the NIH
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The NIH HPC group plans, manages and supports high-performance computing systems specifically for the intramural NIH community. These systems include Biowulf, an 20,000+ processor Linux cluster; Helix, an interactive system for short jobs, Sciware, a set of applications for desktops, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.



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Cluster Utilization
Friday, September 30th, 2016
utilization graph
Last 24 hrs
43,342 jobs submitted
27,440 jobs completed
785,360 CPU hrs used
22 NIH Institutes
114 Principal Investigators
199 users

Announcements
Recent Papers that used Biowulf & HPC Resources

thumbnail image from paper Oncogenic Mutations Differentially Affect Bax Monomer, Dimer, and Oligomeric Pore Formation in the Membrane
Mingzhen Zhang, Jie Zheng, Ruth Nussinov, Buyong Ma
Scientific Reports 6 , 10.1038/srep33340 (2016)

thumbnail image from paper An efficient protocol for obtaining accurate hydration free energies using quantum chemistry and reweighting from molecular dynamics simulations
Frank C. Pickard, Gerhard Koenig, Andrew C. Simmonett, Yihan Shao, Bernard R. Brooks
Bioorganic & Medicinal Chemistry , doi://10.1016/j.bmc.2016.08.031 (2016)

thumbnail image from paper Skin microbiome prior to development of atopic dermatitis: early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year
s: Kennedy EA, Connolly J, O'B Hourihane J, Fallon PG, McLean WI, Murray D, Jo J-H, Segre JA, Kong HH, Irvine AD
J. Allergy and Clinical Immunology , doi: 10.1016/j.jaci.2016.07.029 (2016)

thumbnail image from paper Effects of Gene Dose, Chromatin, and Network Topology on Expression in Drosophila melanogaster
Hangnoh Lee, Dong-Yeon Cho, Cale Whitworth, Robert Eisman, Melissa Phelps, John Roote, Thomas Kaufman, Kevin Cook, Steven Russell, Teresa Przytycka, Brian Oliver
PLoS Genetics , doi://10.1371/journal.pgen.1006295 (2016)

thumbnail image from paper Mechanism of O2 diffusion and reduction in FeFe hydrogenases
A. Kubas, C. Orain et al.
Nature Chemistry , doi:10.1038/nchem.2592 (2016)

thumbnail image from paper Quantifying antiepileptic drug effects using intrinsic excitability measures
Christian Meisel, Dietmar Plenz, Andreas Schulze-Bonhage, Heinz Reichmann
Epilepsia , DOI: 10.1111/epi.13517 (2016)

thumbnail image from paper Genetic causes of moderate to severe hearing loss point to modifiers
S. Naz, A. Imtiaz et al.
Clinical Genetics , DOI: 10.1111/cge.12856 (2016)