Application updates in the last 3 months
To see all versions available for any application, use module avail application_nameAll centrally-installed applications are listed on the Applications page
Updated | Application
5 Jul 2022 | jemalloc updated to version 5.3.0 | jemalloc is a general purpose malloc(3) implementation that emphasizes fragmentation avoidance and scalable concurrency support. 5 Jul 2022 | autoconf updated to version 2.71 | Autoconf is an extensible package of M4 macros that produce shell scripts to automatically configure software source code packages. 1 Jul 2022 | sambamba updated to version 0.8.2 | Sambamba is a high performance modern robust and fast tool (and library), written in the D programming language, for working with SAM and BAM files. Current parallelised functionality is an important subset of samtools functionality, including view, index, sort, markdup, and depth. 29 Jun 2022 | DNAnexus updated to version 0.326.0 | DNAnexus is a cloud-based commercial solution for next-generation sequence analysis and visualization. It has a command-line interface (CLI) which can be used to log in to the DNAnexus platform, upload and navigate data, and launch analyses. 29 Jun 2022 | TElocal updated to version 1.1.2 | TElocal: a tool that utilizes both uniquely and ambiguously mapped reads to quantify transposable element expression at the locus level. 28 Jun 2022 | scChromHMM updated to version 20220610 | scChromHMM provides a suite of tools for rapid processing of single-cell histone modification data to perform chromatin states analysis of the genome within each single-cell. It is an extention of bulk ChromHMM framework, which consumes the HMM model learned from ChromHMM and perform chromatin state analysis by running forward-backward algorithm for each single-cell. 27 Jun 2022 | Neuron updated to version 7.7 | NEURON is a simulation environment for modeling individual neurons and networks of neurons. It provides tools for conveniently building, managing, and using models in a way that is numerically sound and computationally efficient. It is particularly well-suited to problems that are closely linked to experimental data, especially those that involve cells with complex anatomical and biophysical properties. 27 Jun 2022 | XHMM updated to version 2016-01-04 | XHMM uses principal component analysis (PCA) normalization and a hidden Markov model (HMM) to detect and genotype copy number variation (CNV) from normalized read-depth data from targeted sequencing experiments. 27 Jun 2022 | samblaster updated to version 0.1.26 | samblaster is a program for marking duplicates and finding discordant/split read pairs in read-id grouped paired-end SAM files. When marking duplicates, samblaster will use about 20MB per 1M read pairs. In a read-id grouped SAM file all alignments for a read-id (QNAME) are continuous. Aligners naturally produce such files. They can also be created by sorting a SAM file by read-id. 27 Jun 2022 | nanopolish updated to version 0.14.0 | nanopolish is a software package for signal-level analysis of Oxford Nanopore sequencing data. Nanopolish can calculate an improved consensus sequence for a draft genome assembly, detect base modifications, call SNPs and indels with respect to a reference genome and more (see Nanopolish modules, below). 24 Jun 2022 | MIPAV updated to version 11.0.3 | The MIPAV (Medical Image Processing, Analysis, and Visualization) application enables quantitative analysis and visualization of medical images of numerous modalities such as PET, MRI, CT, or microscopy. 24 Jun 2022 | fragpipe updated to version 18.0 | FragPipe is a Java Graphical User Interface (GUI) and CLI workflow tool for a suite of computational tools enabling comprehensive analysis of mass spectrometry-based proteomics data. It is powered by MSFragger. 24 Jun 2022 | ea-utils updated to version 1.04.807 | Command-line tools for processing biological sequencing data. Barcode demultiplexing, adapter trimming, etc. 24 Jun 2022 | MUSCLE updated to version 5.1 | Fast Multiple Sequence Alignment program. 23 Jun 2022 | STAR updated to version 2.7.9a | Spliced Transcripts Alignment to a Reference 23 Jun 2022 | ionquant updated to version 1.8.0 | IonQuant is a fast and comprehensive tool for MS1 precursor intensity-based quantification for timsTOF PASEF DDA and non-timsTOF (e.g., Orbitrap) data. It enables label-free quantification with false discovery (FDR) controlled match-between-runs (MBR). It can also be used for quantification in labelling-based experiments such as those involving SILAC, dimethyl, or similar labelling strategies. IonQuant is available as part of FragPipe (recommended option), but can also be run as a command-line tool. 23 Jun 2022 | tmux updated to version 3.3a | tmux is a terminal multiplexer. Type 'module load tmux' to load the module, then 'tmux --help' 23 Jun 2022 | trimmomatic updated to version 0.39 | Trimmomatic performs a variety of useful trimming tasks for illumina paired-end and single ended data. 23 Jun 2022 | philosopher updated to version 4.2.2 | Philosopher is fast, easy-to-use, scalable, and versatile data analysis software for mass spectrometry-based proteomics. Philosopher is dependency-free and can analyze both traditional database searches and open searches for post-translational modification (PTM) discovery. 23 Jun 2022 | arcashla updated to version 0.5.0 | high resolution HLA typing from RNA seq 23 Jun 2022 | Genome Browser updated to version 432 | The Genome Browser Mirror Fragments is a mirror of the UCSC Genome Browser. The URL is https://hpcnihapps.cit.nih.gov/genome. Users can also access the MySQL databases, supporting files directly, and a huge number of associated executables. 23 Jun 2022 | Gromacs updated to version 2021.3 | Gromacs is a versatile package to perform molecular dynamics, i.e. simulate the Newtonian equations of motion for systems with hundreds to millions of particles. It is primarily designed for biochemical molecules like proteins and lipids that have a lot of complicated bonded interactions, but since GROMACS is extremely fast at calculating the nonbonded interactions (that usually dominate simulations) many groups are also using it for research on non-biological systems, e.g. polymers. 23 Jun 2022 | MuSE updated to version 2.0 | MuSE is an approach to somatic variant calling based on the F81 Markov substitution model for molecular evolution, which models the evolution of the reference allele to the allelic composition of the matched tumor and normal tissue at each genomic locus. 22 Jun 2022 | xcp_d updated to version 0.0.9 | xcp_d is a postprocessing and noise regression pipeline for fMRI datasets (can use output from fmriprep and nibabies). 22 Jun 2022 | pb-cpg-tools updated to version 1.1.0 | Tools for analyzing CpG/5mC data from PacBio HiFi reads aligned to a reference genome 22 Jun 2022 | shasta updated to version 0.10.0 | De novo assembly from Oxford Nanopore reads 22 Jun 2022 | Java updated to version 17.0.3.1 | Java is a high-level language and software-only platform. The two main components of the Java platform are the Java Application Programming Interface (API), which is a library of Java command lines and the Java Virtual Machine (JVM) that interprets Java code into machine language. 22 Jun 2022 | parallel updated to version 20220622 | GNU parallel is a shell tool for executing jobs in parallel using one or more computers. 22 Jun 2022 | snpEff updated to version 5.1d | snpEff is a variant annotation and effect prediction tool. It annotates and predicts the effects of variants on genes (such as amino acid changes). 21 Jun 2022 | hisat updated to version 2.2.2.1-ngs3.0.0 | HISAT is a fast and sensitive spliced alignment program which uses Hierarchical Indexing for Spliced Alignment of Transcripts. 21 Jun 2022 | Beagle updated to version 5.4_18Mar22 | Beagle is a package for imputing genotypes, inferring haplotype phase, and performing genetic association analysis. BEAGLE is designed to analyze large-scale data sets with hundreds of thousands of markers genotyped on thousands of samples. 17 Jun 2022 | Julia updated to version 1.7.3 | high level, dynamic language for technical computing 17 Jun 2022 | cpdf updated to version 2.5.1 | Coherent PDF tools 17 Jun 2022 | minimac updated to version 4 (1.0.1) | minimac is a low memory, computationally efficient implementation of the MaCH algorithm for genotype imputation. It is designed to work on phased genotypes and can handle very large reference panels with hundreds or thousands of haplotypes. 'mini' refers to the low amount of computational resources it needs. 16 Jun 2022 | samtools updated to version 1.15.1 | The samtools package now provides samtools, bcftools, tabix, and the underlying htslib library. 16 Jun 2022 | Emacs updated to version 28.1 | Emacs is a text and source code editor for text terminals and X. It has a vast set of features and is well suited for doing everything from reading mail and simple text editing to managing and editing large programming projects. It has its own help and tutorial which can be accessed by typing Ctrl-h i and Ctrl-h t respectively. Type emacs [filename] to edit a file. For more info, see here. 16 Jun 2022 | globus-cli updated to version 3.6.0 | Globus command line interface 16 Jun 2022 | NAMD updated to version 2.14 | NAMD is a parallel molecular dynamics program for UNIX platforms designed for high-performance simulations in structural biology. VMD, the associated molecular visualization program, is also available. 16 Jun 2022 | git updated to version 2.36.1 | Git is a free and open source distributed version control system designed to handle everything from small to very large projects with speed and efficiency. 16 Jun 2022 | pandoc updated to version 2.18 | Pandoc is a Haskell library for converting from one markup format to another, and a command-line tool that uses this library. 15 Jun 2022 | netcdf updated to version 4.9.0 | NetCDF (network Common Data Form) is a set of software libraries and machine-independent data formats that support the creation, access, and sharing of array-oriented scientific data. 15 Jun 2022 | Grace updated to version 5.1.25 | Grace is a WYSIWYG 2D plotting tool for the X-Window system. It is a successor to Xmgr. Type 'module load grace', then 'xmgrace' or 'gracebat' to run. 15 Jun 2022 | FFmpeg updated to version 5.0.1 | A complete, cross-platform solution to record, convert and stream audio and video. 14 Jun 2022 | sodium updated to version 1.0.18 | Sodium is a modern, easy-to-use software library for encryption, decryption, signatures, password hashing, and more. 14 Jun 2022 | Rstudio updated to version 2022.02.3-492 | RStudio is a set of integrated tools designed to help you be more productive with R. It includes a console, syntax-highlighting editor that supports direct code execution, as well as tools for plotting, history, debugging and workspace management. 14 Jun 2022 | jags updated to version 4.3.1 | Just another Gibbs sampler 14 Jun 2022 | AutodockVina updated to version 1_1_2 | AutoDock Vina is a program for drug discovery, molecular docking and virtual screening, offering multi-core capability, high performance and enhanced accuracy and ease of use. It is closely tied to Autodock. 14 Jun 2022 | Autodock updated to version 4.2.6 | Autodock is a suite of automated docking tools. It is designed to predict how small molecules, such as substrates or drug candidates, bind to a receptor of known 3D structure. 14 Jun 2022 | metal updated to version 2020-05-05 | The METAL software is designed to facilitate meta-analysis of large datasets (such as several whole genome scans) in a convenient, rapid and memory efficient manner. 14 Jun 2022 | udunits updated to version 2.2.28 | The UDUNITS-2 package provides support for units of physical quantities. Its three main components are: 1) (udunits2lib)a C library for units of physical quantities; 2) (udunits2prog)a utility; for obtaining the definition of a unit and for converting numeric values between compatible units; and 3) an extensive database of units. 14 Jun 2022 | treetime updated to version 0.9.0 | TreeTime provides routines for ancestral sequence reconstruction and inference of molecular-clock phylogenies. 13 Jun 2022 | Autodock-GPU updated to version 1.5.3 | Autodock-GPU performs docking calculations, and processes ligand-receptor poses in parallel over multiple compute units on GPUs. 13 Jun 2022 | asciinema updated to version 2.2.0 | asciinema [as-kee-nuh-muh] is a free and open source solution for recording terminal sessions and sharing them. Type 'module load asciinema' then 'asciinema' to run. 10 Jun 2022 | picard updated to version 2.27.3 | Picard comprises Java-based command-line utilities that manipulate SAM files, and a Java API (SAM-JDK) for creating new programs that read and write SAM files. Both SAM text format and SAM binary (BAM) format are supported. 10 Jun 2022 | mixcr updated to version 4.0.0 | MiXCR is a universal software for fast and accurate analysis of T- and B- cell receptor repertoire sequencing data. 10 Jun 2022 | gdal updated to version 3.5.0 | GDAL is a translator library for raster and vector geospatial data formats 10 Jun 2022 | SAIGE updated to version 1.0.9 | R package for large-scale genetic association studies. 10 Jun 2022 | proj updated to version 6.3.2 | PROJ is a generic coordinate transformation software that transforms geospatial coordinates from one coordinate reference system (CRS) to another 9 Jun 2022 | SQLite updated to version 3.38.5 | SQLite is a software library that implements a self-contained, serverless, zero-configuration, transactional SQL database engine. 9 Jun 2022 | inkscape updated to version 1.2 | Inkscape is a Free and open source vector graphics editor 9 Jun 2022 | caper updated to version 2.1.3 | A Python-based wrapper for the Cromwell pipeline system used by ENCODE pipelines. Includes the croo and qc2tsv commands for parsing Cromwell and quality control output. 8 Jun 2022 | geos updated to version 3.10.3 | GEOS is a C/C++ library for computational geometry with a focus on algorithms used in geographic information systems (GIS) software. 8 Jun 2022 | nibabies updated to version 22.0.2 | Preprocessing pipeline for neonate and infant MRI. 8 Jun 2022 | R updated to version 4.2.0 | R (the R Project) is a language and environment for statistical computing and graphics. R is similar to S, and provides a wide variety of statistical and graphical techniques (linear and nonlinear modelling, statistical tests, time series analysis, classification, clustering, ...). 7 Jun 2022 | Gemini updated to version 0.30.2 | GEMINI (GEnome MINIng) is designed to be a flexible framework for exploring genetic variation in the context of the wealth of genome annotations available for the human genome. By placing genetic variants, sample genotypes, and useful genome annotations into an integrated database framework, GEMINI provides a simple, flexible, yet very powerful system for exploring genetic variation for for disease and population genetics. 7 Jun 2022 | phaser updated to version 1.1.1 | phasing and Allele Specific Expression from RNA-seq. Performs haplotype phasing using read alignments in BAM format from both DNA and RNA based assays, and provides measures of haplotypic expression for RNA based assays. 7 Jun 2022 | biom-format updated to version 2.1.12 | tool (and library) to manipulate Biological Observation Matrix (BIOM) Format files 6 Jun 2022 | chipseq_pipeline updated to version 2.1.6 | AQUAS Transcription Factor and Histone ChIP-Seq processing pipeline. The AQUAS pipeline is based off the ENCODE (phase-3) transcription factor and histone ChIP-seq pipeline specifications (by Anshul Kundaje) 6 Jun 2022 | deepvariant updated to version 1.4.0 | DeepVariant is an analysis pipeline that uses a deep neural network to call genetic variants from next-generation DNA sequencing data. 6 Jun 2022 | clustalo updated to version 1.2.4 | Clustal-Omega is a general purpose multiple sequence alignment (MSA) program for proteins and DNA/RNA. It produces high quality MSAs and is capable of handling data-sets of hundreds of thousands of sequences in reasonable time. 6 Jun 2022 | AnnotSV updated to version 3.1.1 | AnnotSV is a program designed for annotating Structural Variations (SV). This tool compiles functionally, regulatory and clinically relevant information and aims at providing annotations useful to i) interpret SV potential pathogenicity and ii) filter out SV potential false positives. 6 Jun 2022 | CD-HIT updated to version 4.6.8 | CD-HIT is a very widely used program for clustering and comparing protein or nucleotide sequences. 4 Jun 2022 | foldseek updated to version 1-2dd3b2f | Fast structural similarity search 3 Jun 2022 | seqkit updated to version 2.2.0 | A cross-platform toolkit for FASTA/Q file manipulation 3 Jun 2022 | csvkit updated to version 1.0.7 | csvkit is a suite of command-line tools for converting to and working with CSV, the king of tabular file formats. 3 Jun 2022 | FastTree updated to version 2.1.11 | FastTree infers approximately-maximum-likelihood phylogenetic trees from alignments of nucleotide or protein sequences. FastTree can handle alignments with up to a million of sequences in a reasonable amount of time and memory. For large alignments, FastTree is 100-1,000 times faster than PhyML 3.0 or RAxML 7. 3 Jun 2022 | AfterQC updated to version 0.9.7 | Automatic Filtering, Trimming, Error Removing and Quality Control for fastq data. 3 Jun 2022 | admixture updated to version 1.3.0 | ADMIXTURE is a software tool for maximum likelihood estimation of individual ancestries from multilocus SNP genotype datasets. It uses the same statistical model as STRUCTURE but calculates estimates much more rapidly using a fast numerical optimization algorithm. 3 Jun 2022 | ANTs updated to version 2.3.5 | Advanced Normalization Tools (ANTs) extracts information from complex datasets that include imaging. Paired with ANTsR (answer), ANTs is useful for managing, interpreting and visualizing multidimensional data. 1 Jun 2022 | htseq updated to version 2.0.1 | HTSeq is a Python package that provides infrastructure to process data from high-throughput sequencing assays. 1 Jun 2022 | HMMER updated to version 3.3.2 | HMMER is used for searching sequence databases for homologs of protein sequences, and for making protein sequence alignments. It implements methods using probabilistic models called "profile hidden Markov models" (profile HMMs). Compared to BLAST, FASTA, and other sequence alignment and database search tools based on older scoring methodology, HMMER aims to be significantly more accurate and more able to detect remote homologs because of the strength of its underlying mathematical models. 1 Jun 2022 | MONAILabel updated to version 0.3.2; 0.4.0rc4 | MONAI Label is a free and open-source platform that facilitates the development of AI-based applications that aim at reducing the time required to annotate 3D medical image datasets. It allows researchers to readily deploy their apps as services, which can be made available to clinicians via their preferred user-interface. Currently, MONAI Label readily supports locally installed (3DSlicer) and web-based (OHIF) frontends, and offers two Active learning strategies to facilitate and speed up the training of segmentation algorithms. MONAI Label allows researchers to make incremental improvements to their labeling apps by making them available to other researchers and clinicians alike. 31 May 2022 | sratoolkit updated to version 3.0.0 | The NCBI SRA Toolkit enables reading ("dumping") of sequencing files from the SRA database and writing ("loading") files into the .sra format. |