The NIH HPC group plans, manages and supports
high-performance computing systems specifically for use by the
intramural NIH community. These systems include
Biowulf,
a 105,000+ processor
Linux cluster;
Helix, an interactive system for
file transfer and management, and
Helixweb, which provides a number of web-based
scientific tools. We provide access to a wide range of computational
applications for genomics, molecular and structural biology, mathematical and
graphical analysis, image analysis, and other scientific fields.
Quick Links
Biowulf Utilization
Tuesday, March 19th, 2024
Last 24 hrs
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134,490 jobs submitted
102,699 jobs completed
2,860,570 CPU hrs used
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25 NIH Institutes
289 Principal Investigators
633 users
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Announcements
COVID-19 Research Support
The enhanced priority for Covid-related projects on Biowulf was retired in June 2023. Since 2020, this priority has resulted in
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Recent Papers that used Biowulf & HPC Resources
An unusual dual sugar-binding lectin domain controls the substrate specificity of a mucin-type O-glycosyltransferase Collette, AM; Hassan, SA; Schmidt, SI et al.
Sci Adv
, DOI://10.1126/sciadv.adj8829 (2024)
The cysteine-rich domain in CENP-A chaperone Scm3HJURP ensures centromere targeting and kinetochore integrity Folco, HD; Xiao, H; Wheeler, D et al.
Nucleic Acids Res
, DOI://10.1093/nar/gkad1182 (2024)
ATOH1, TFAP2B, and CEACAM6 as Immunohistochemical Markers to Distinguish Merkel Cell Carcinoma and Small Cell Lung Cancer Vilasi, SM; Nguyen, J; Wang, CJ et al.
Cancers (Basel)
, DOI://10.3390/cancers16040788 (2024)
Lithium response in bipolar disorder is associated with focal adhesion and PI3K-Akt networks: a multi-omics replication study Ou, AH; Rosenthal, SB; Adli, M et al.
Transl Psychiatry
, DOI://10.1038/s41398-024-02811-4 (2024)
Comparative evolution of influenza A virus H1 and H3 head and stalk domains across host species Trovão, NS; Khan, SM; Lemey, P et al.
mBio
, DOI://10.1128/mbio.02649-23 (2024)
Genetic analysis of the X chromosome in people with Lewy body dementia nominates new risk loci Bayram, E; Reho, P; Litvan, I et al.
NPJ Parkinsons Dis
, DOI://10.1038/s41531-024-00649-7 (2024)
Multifaceted roles for STAT3 in gammaherpesvirus latency revealed through in vivo B cell knockout models Hogan, CH; Owens, SM; Reynoso, GV et al.
mBio
, DOI://10.1128/mbio.02998-23 (2024)
Association of cardiovascular disease management drugs with Lewy body dementia: a case-control study Scholz, SW; Moroz, BE; Saez-Atienzar, S et al.
Brain Commun
, DOI://10.1093/braincomms/fcad346 (2024)
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